Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CAF1B_HUMAN
Description:chromatin assembly factor 1, subunit B (p60) [Source:HGNC Symbol;Acc:1911]
Location:chr21 q22.12
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S538GDAQGsPPELKPhosphoSitePlus; HPRD; phosphoELM
T432PSSPGtTPPQAPhosphoSitePlus; HPRD; phosphoELM
S428RTQDPsSPGTTPhosphoSitePlus; HPRD
S458TPAVKsPLPGPPhosphoSitePlus; HPRD; phosphoELM
S464PLPGPsEEKTLPhosphoSitePlus
T419RPVEGtPASRTPhosphoSitePlus; HPRD; phosphoELM
T524ISTPStEEIQSPhosphoSitePlus; HPRD; phosphoELM
S520PTSVIsTPSTEphosphoELM
T433SSPGTtPPQARPhosphoSitePlus; HPRD; phosphoELM
T509PLKTDtPPSSVphosphoELM
T503RRINLtPLKTDPhosphoSitePlus; HPRD; phosphoELM
S556KGGTEsLDP__PhosphoSitePlus
S422EGTPAsRTQDPPhosphoSitePlus; HPRD
T39SAGVDtNVRIWWD40PhosphoSitePlus
S410THRGSsPGPRPPhosphoSitePlus; HPRD; phosphoELM
T485PSRRVtLNTLQPhosphoSitePlus; HPRD
S409QTHRGsSPGPRPhosphoSitePlus; HPRD; phosphoELM
S512TDTPPsSVPTSHPRD; phosphoELM
S34IHRLAsAGVDTWD40PhosphoSitePlus
S473TLQPSsQNTKAHPRD
S529TEEIQsETPGDPhosphoSitePlus; HPRD
T424TPASRtQDPSSPhosphoSitePlus
T531EIQSEtPGDAQPhosphoSitePlus
T496AWSKTtPRRINPhosphoSitePlus
S429TQDPSsPGTTPPhosphoSitePlus; HPRD; phosphoELM

Dephosphorylation site
CAF1B_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000315700T419PBIOMARTBreast Cancer21930507, 21930502
ENSP00000315700D38YTCGAOvarian Cancer21720365, 18772890
ENSP00000315700D38YCOSMICOvarian Cancer21720365
ENSP00000315700R292CCOSMICMelanoma21499247

Differential expressed protein
CAF1B_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CAF1B_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ST17A_HUMANCAF1B_HUMANkinase -> substrateRobert H Newman (2013)
KPCA_HUMANCAF1B_HUMANkinase -> substrateRobert H Newman (2013)
STK16_HUMANCAF1B_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
CAF1B_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIEAmolecular_function
GO:0042393histone bindingNASmolecular_function
GO:0006461protein complex assemblyTASbiological_process
GO:0006260DNA replicationIEAbiological_process
GO:0005654nucleoplasmIDAcellular_component
GO:0005829cytosolIDAcellular_component
GO:0033186CAF-1 complexIDAcellular_component
GO:0005737cytoplasmNAScellular_component
GO:0031497chromatin assemblyIDAbiological_process
GO:0003682chromatin bindingTASmolecular_function
GO:0005634nucleusIDAcellular_component
GO:0006335DNA replication-dependent nucleosome assemblyTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0005678chromatin assembly complexTAScellular_component
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0006281DNA repairIEAbiological_process
GO:0007049cell cycleIEAbiological_process
GO:0051082unfolded protein bindingTASmolecular_function


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