Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:BHE40_HUMAN
Description:basic helix-loop-helix family, member e40 [Source:HGNC Symbol;Acc:1046]
Location:chr3 p26.1
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y37HMYQVyKSRRGPhosphoSitePlus

Dephosphorylation site
BHE40_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000256495P324ATCGAOvarian Cancer21720365, 18772890
ENSP00000256495P384TCOSMICSkin Cancer21984974
ENSP00000256495P324ACOSMICOvarian Cancer21720365

Differential expressed protein
BHE40_HUMAN is not differential expressed protein.

Hyperphosphorylation site
BHE40_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
BHE40_HUMANBHE41_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
BHE40_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007623circadian rhythmIEAbiological_process
GO:0070888E-box bindingIDAmolecular_function
GO:0043153entrainment of circadian clock by photoperiodISSbiological_process
GO:0046982protein heterodimerization activityIPImolecular_function
GO:0042803protein homodimerization activityIDAmolecular_function
GO:0005730nucleolusIDAcellular_component
GO:0019904protein domain specific bindingIPImolecular_function
GO:0009416response to light stimulusIEAbiological_process
GO:0000981sequence-specific DNA binding RNA polymerase II trIDAmolecular_function
GO:0001102RNA polymerase II activating transcription factor ISSmolecular_function
GO:0001102RNA polymerase II activating transcription factor IEAmolecular_function
GO:0043425bHLH transcription factor bindingIPImolecular_function
GO:0001078RNA polymerase II core promoter proximal region seIEAmolecular_function
GO:0001078RNA polymerase II core promoter proximal region seIDAmolecular_function
GO:0006355regulation of transcription, DNA-dependentNASbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0005794Golgi apparatusIDAcellular_component
GO:0043426MRF bindingIEAmolecular_function
GO:0003705RNA polymerase II distal enhancer sequence-specifiISSmolecular_function
GO:0070888E-box bindingIEAmolecular_function
GO:0043153entrainment of circadian clock by photoperiodIEAbiological_process
GO:0032922circadian regulation of gene expressionIEAbiological_process
GO:0005634nucleusIDAcellular_component
GO:0045892negative regulation of transcription, DNA-dependenIEAbiological_process
GO:0001191RNA polymerase II transcription factor binding traIDAmolecular_function
GO:0003705RNA polymerase II distal enhancer sequence-specifiIEAmolecular_function
GO:0000122negative regulation of transcription from RNA polyIDAbiological_process
GO:0043433negative regulation of sequence-specific DNA bindiIDAbiological_process
GO:0046982protein heterodimerization activityIEAmolecular_function
GO:0046983protein dimerization activityIEAmolecular_function
GO:0003700sequence-specific DNA binding transcription factorNASmolecular_function
GO:0006366transcription from RNA polymerase II promoterIDAbiological_process
GO:0032922circadian regulation of gene expressionIDAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0005515protein bindingIEAmolecular_function
GO:0043426MRF bindingISSmolecular_function