| UniProt/SwissProt ID: | BANK1_HUMAN |
| Description: | B-cell scaffold protein with ankyrin repeats 1 [Source:HGNC Symbol;Acc:18233] |
| Location: | chr4 q24 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S66 | RLENFsFRHLE | PhosphoSitePlus | |
| Y630 | EETTPyIAQVF | PhosphoSitePlus | |
| S148 | PEDYIsVIQSI | PhosphoSitePlus | |
| Y737 | EEENVyNKLTI | PhosphoSitePlus | |
| Dephosphorylation site |
| BANK1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000320509 | N25K | COSMIC | Ovarian Cancer | 21720365 | ENSP00000421443 | F764L | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000320509 | F779L | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000412748 | F646L | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000421443 | W355X | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000388817 | F749L | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000320509 | T94I | COSMIC | Ovarian Cancer | 21720365 | ENSP00000422314 | F646L | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000320509 | D646N | COSMIC | Melanoma | 21499247 |
| Differential expressed protein |
| BANK1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| BANK1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| LYN_HUMAN | BANK1_HUMAN | kinase -> substrate | NetPath |
| Function Annotation |
| KEGG Pathway |
| BANK1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0042113 | B cell activation | IEA | biological_process |