Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:APJ_HUMAN
Description:apelin receptor [Source:HGNC Symbol;Acc:339]
Location:chr11 q12.1
Node attribute:receptor; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y264LCWMPyHLVKT7tm_1; TMPhosphoSitePlus
S248RRRLLsIIVVL7tm_1; TMPhosphoSitePlus

Dephosphorylation site
APJ_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000257254E367KCOSMICLung Cancer20668451
ENSP00000257254Y11NCOSMICLung Cancer20668451
ENSP00000257254T52NCOSMICLung Cancer20668451
ENSP00000257254R127HCOSMICLung Cancer20668451
ENSP00000257254R233LCOSMICLung Cancer20668451
ENSP00000257254C281YCOSMICOvarian Cancer20668451

Differential expressed protein
APJ_HUMAN is not differential expressed protein.

Hyperphosphorylation site
APJ_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
APEL_HUMANAPJ_HUMANligand -> receptorHPMR
IP3KA_HUMANAPJ_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0016021integral to membraneIEAcellular_component
GO:0050909sensory perception of tasteIEAbiological_process
GO:0016020membraneIEAcellular_component
GO:0004872receptor activityTASmolecular_function
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0005886plasma membraneTAScellular_component
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0050878regulation of body fluid levelsIEAbiological_process
GO:0005887integral to plasma membraneTAScellular_component


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