eGFR decline (a decline in eGFR category (>=90 [stage 1], 60–89 [stage 2], 45–59 [stage 3a], 30–44 [stage 3b], 15–29 [stage 4], and <15 [stage 5] mL/min/1.73 m2), accompanied by a 25% or greater deterioration in eGFR from baseline . eGFR was calculated using MDRD) 