MS Experiments: 779
Cancer-related Differentially Expressed Proteins: 11,669
Cancer-related Amino Acid Variations: 213,0668
Post Translational Modifications: 110,343
Drugs: 4,908
dbDEPC 2.0: updated database of differentially expressed proteins in human cancers. Nucleic Acids Research 2011 [Full Text].
dbDEPC: a database of differentially expressed proteins in human cancers. Nucleic Acids Research 2009 [Full Text].
| Through mining published researches with detailed experiment information, dbDEPC was the first database aimed to provide a systematic resource for the storage and query of the DEPs generated by mass spectrometry in human cancers. It was updated in 2012. Here, we give another updated version of dbDEPC, with improvement of database contents and enhanced web interface. |
| In the current version, dbDEPC contains 11669 unique DEPs in 26 different cancer types (). Multi-level annotations of DEPs have been firstly introduced this time, including cancer-related amino acid variations, PTMs, and drug information. Moreover, these multi-level annotations will be displayed in the biological networks, which can benefit integrative analysis. Finally, an online enrichment analysis tool has been developed, to support a KEGG enrichment analysis and to browse the relations between interested protein list and known DEPs in KEGG pathways. |
| In summary, dbDEPC 3.0 provides a comprehensive resource for accessing integrated and highly annotated DEPs in human cancer. |
@2017 Qingmin Yang, Yuqi Zhang, Menghuan Zhang, Lu Xie
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