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Powered by Manman Lu, Linfeng Xu, Lu Xie

dbPepNeo 2.0 is a collected neoantigen database, including human leukocyte antigen class I (HLA-Ⅰ) and Ⅱ (HLA-Ⅱ). In dbPepNeo 2.0, all neoantigen peptides have been validated by mass spectrometry (MS) or immunoassay. In particular, the peptides only identified by MS and bound by HLA-I/HLA-Ⅱ molecules were defined as low-confidence (LC) peptidomes; the peptides containing somatic mutations based on WES/WGS and confirmed by MS were treated as medium confidence (MC) neoantigens; the immunogenic peptides validated by specific TCRs recognition were considered as high confidence (HC) neoantigens. Moreover, several meaningful tools are integrated in dbPepNeo 2.0, such as ProGeo-neo, INeo-EPP, DeepCNN-Ineo, BLASTdb.

Welcome to the dbPepNeo（V2.0）

1.Please select search type：

2.Input：

E.g. melanoma/DCAKD/YPVIFKSIM/HLA-A*02:01

Note：

1. You can simultaneously query cancer, multiple peptides, genes, HLA alleles.

2. Cancer types: melanoma, non-small cell lung cancer (NSCLC), pancreatic cancer, glioblastoma (GBM), breast cancer, gastric cancer, medulloblastoma, bile duct, hepatocellular carcinoma, cervical carcinoma, colon cancer, esophageal cancer, head and neck squamous cell carcinoma (HNSCC), adenoid cystic carcinoma, neuroblastoma, alveolar rhabdomyosarcoma cells, collecting duct carcinoma, diffuse intrinsic pontine glioma, endometrial, liver cancer, mesothelioma, thymoma, bladder cancer, rectal cancer, HCT 116 cell line.