Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeat; pfam00435
Src homology 3 domain of Alpha Spectrin; cd11808
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeat; pfam00435
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Ca2+ insensitive EF hand; pfam08726
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Nucleosome assembly protein (NAP); pfam00956
(NAP-L) nucleosome assembly protein -L; Provisional; cl08298
Nucleosome assembly protein (NAP); pfam00956
(NAP-L) nucleosome assembly protein -L; Provisional; cl08298
Nucleosome assembly protein (NAP); pfam00956
(NAP-L) nucleosome assembly protein -L; Provisional; cl08298
Nucleosome assembly protein (NAP); pfam00956
(NAP-L) nucleosome assembly protein -L; Provisional; cl08298
First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N; cd11622
Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N3; cd11632
Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases; cl00087
C2 domain; cl14603
Catalytic domain of the Protein Serine/Threonine Kinase, Protein Kinase N; cd05589
Serine/Threonine protein kinases, catalytic domain; smart00220
DHHC palmitoyltransferase; pfam01529
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Rab-GTPase-TBC domain; cl02495
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; cd00091
DNA/RNA non-specific endonuclease; smart00892
Putative RNA methyltransferase; pfam02598
aminotransferase family protein; Provisional
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; cd00609
hypothetical protein; Provisional
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; cd00609
hypothetical protein; Provisional
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; cd00609
Leucine-rich repeat containing protein 8; pfam12534
Leucine-rich repeat containing protein 8; pfam12534
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeat containing protein 8; pfam12534
Leucine-rich repeat containing protein 8; pfam12534
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeat containing protein 8; pfam12534
Leucine-rich repeat containing protein 8; pfam12534
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
2OG-Fe(II) oxygenase superfamily; cl15773
Phytanoyl-CoA dioxygenase (PhyH); pfam05721
Phytanoyl-CoA dioxygenase (PhyH); pfam05721
Dolichol kinase [Lipid metabolism]; COG0170
Nucleoporin subcomplex protein binding to Pom34; pfam10487
BAR domain; smart00721
The Bin/Amphiphysin/Rvs (BAR) domain of Endophilin-B2; cd07617
Src Homology 3 domain superfamily; cl17036
Uncharacterized conserved protein (DUF2217); pfam10265
PAP2_like proteins, dolichyldiphosphatase subfamily. Dolichyldiphosphatase is a membrane-associated protein located in the endoplasmic reticulum and hydrolyzes dolichyl pyrophosphate, as well as dolichylmonophosphate at a low rate. The enzyme is...; cd03382
PAP2_like proteins, dolichyldiphosphatase subfamily. Dolichyldiphosphatase is a membrane-associated protein located in the endoplasmic reticulum and hydrolyzes dolichyl pyrophosphate, as well as dolichylmonophosphate at a low rate. The enzyme is...; cd03382
Choline/Carnitine o-acyltransferase; pfam00755
Choline/Carnitine o-acyltransferase; pfam00755
Phosphotyrosyl phosphatase activator (PTPA) is also known as protein phosphatase 2A (PP2A) phosphatase activator. PTPA is an essential, well conserved protein that stimulates the tyrosyl phosphatase activity of PP2A. It also reactivates the serine...; cd04087
Phosphotyrosyl phosphatase activator (PTPA) is also known as protein phosphatase 2A (PP2A) phosphatase activator. PTPA is an essential, well conserved protein that stimulates the tyrosyl phosphatase activity of PP2A. It also reactivates the serine...; cd04087
Phosphotyrosyl phosphatase activator (PTPA) is also known as protein phosphatase 2A (PP2A) phosphatase activator. PTPA is an essential, well conserved protein that stimulates the tyrosyl phosphatase activity of PP2A. It also reactivates the serine...; cd04087
Phosphotyrosyl phosphatase activator (PTPA) is also known as protein phosphatase 2A (PP2A) phosphatase activator. PTPA is an essential, well conserved protein that stimulates the tyrosyl phosphatase activity of PP2A. It also reactivates the serine...; cd04087
Phosphotyrosyl phosphatase activator (PTPA) is also known as protein phosphatase 2A (PP2A) phosphatase activator. PTPA is an essential, well conserved protein that stimulates the tyrosyl phosphatase activity of PP2A. It also reactivates the serine...; cd04087
Immediate early response protein (IER); pfam05760
Immediate early response protein (IER); pfam05760
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
SOCS (suppressors of cytokine signaling) box of ASB6-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ASB6 interacts with the adaptor protein APS and recruits elongin B/C to the insulin receptor...; cd03725
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
SOCS (suppressors of cytokine signaling) box of ASB6-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ASB6 interacts with the adaptor protein APS and recruits elongin B/C to the insulin receptor...; cd03725
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
OAR domain; pfam03826
MAPEG family; pfam01124
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Hepatocellular carcinoma-associated antigen 59; pfam07052
Zn-finger in ubiquitin-hydrolases and other protein; pfam02148
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02674
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Domain in ubiquitin-specific proteases; smart00695
Domain in ubiquitin-specific proteases; smart00695
Zn-finger in ubiquitin-hydrolases and other protein; pfam02148
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02674
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Domain in ubiquitin-specific proteases; smart00695
Domain in ubiquitin-specific proteases; smart00695
Zn-finger in ubiquitin-hydrolases and other protein; pfam02148
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02674
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Domain in ubiquitin-specific proteases; smart00695
Domain in ubiquitin-specific proteases; smart00695
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Formin Binding Protein 17; cd07676
Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Formin Binding Protein 17; cd11629
Src Homology 3 domain of Formin Binding Protein 17; cd12071
Lung seven transmembrane receptor; pfam06814
Lung seven transmembrane receptor; pfam06814
Lung seven transmembrane receptor; pfam06814
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Argininosuccinate synthase [Amino acid transport and metabolism]; COG0137
Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; cd01999
Argininosuccinate synthase [Amino acid transport and metabolism]; COG0137
Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; cd01999
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
SET domain; pfam00856
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain) [Translation, ribosomal structure and biogenesis]; COG1097
Exosome complex exonuclease RRP4 N-terminal region; pfam14382
S1_Rrp4: Rrp4 S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. Rrp4 protein is a subunit of the exosome complex. The exosome plays a central role in 3' to 5' RNA processing and degradation in...; cd05789
Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase; cd11850
Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins; cd09935
Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase; cd05052
Protein tyrosine kinase; pfam07714
F-actin binding; pfam08919
Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase; cd11850
Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins; cd09935
Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase; cd05052
Protein tyrosine kinase; pfam07714
F-actin binding; pfam08919
Orexigenic neuropeptide Qrfp/P518; pfam11109
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
Laminin N-terminal domain (domain VI); smart00136
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin B (Domain IV); cl02548
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cl08302
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to eukaryota, lacks functional characterization and may act as a...; cd03391
Membrane-associated phospholipid phosphatase [Lipid metabolism]; COG0671
BAT2 N-terminus; pfam07001
Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]; COG1928
Dolichyl-phosphate-mannose-protein mannosyltransferase; pfam02366
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]; COG1928
Dolichyl-phosphate-mannose-protein mannosyltransferase; pfam02366
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]; COG1928
Dolichyl-phosphate-mannose-protein mannosyltransferase; pfam02366
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Dolichyl-phosphate-mannose-protein mannosyltransferase; pfam02366
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
MIR domain; pfam02815
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Dolichyl-phosphate-mannose-protein mannosyltransferase; pfam02366
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
MIR domain; pfam02815
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Uridine kinase [Nucleotide transport and metabolism]; COG0572
Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; cd02023
Uridine kinase [Nucleotide transport and metabolism]; COG0572
Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; cd02023
Uridine kinase [Nucleotide transport and metabolism]; COG0572
Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; cd02023
Uridine kinase [Nucleotide transport and metabolism]; COG0572
Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; cd02023
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
Mediator complex subunit 27; pfam11571
Mediator complex subunit 27; pfam11571
Laminin N-terminal (Domain VI); cl02806
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
AAA domain; pfam13086
UvrD/REP helicase N-terminal domain; pfam00580
AAA domain; pfam13087
Myb-like DNA-binding domain; pfam13921
Myb-like DNA-binding domain; pfam13921
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
ATP-dependent RNA helicase RhlB; Provisional
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Domain of unknown function (DUF4217); pfam13959
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
DEAD-like helicases superfamily; smart00487
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Transcription factor IIIC subunit delta N-term; pfam12657
Putative zinc-finger of transcription factor IIIC complex; pfam12660
adenylate kinases; TIGR01351
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; cd01428
adenylate kinases; TIGR01351
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; cd01428
Hamartin protein; pfam04388
TPR/MLP1/MLP2-like protein; pfam07926
Snf7; cl02305
N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; cl00357
Hamartin protein; pfam04388
TPR/MLP1/MLP2-like protein; pfam07926
Snf7; cl02305
N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; cl00357
Hamartin protein; pfam04388
TPR/MLP1/MLP2-like protein; pfam07926
Snf7; cl02305
N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; cl00357
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
RNA polymerase III transcription factor (TF)IIIC subunit; pfam09734
RNA polymerase III transcription factor (TF)IIIC subunit; pfam09734
Carboxylesterase family; pfam00135
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cd00312
Uracil-DNA glycosylases (UDG) and related enzymes; cl00483
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
Ubiquitin domain of  RalGDS-like factor (RLF) and related proteins; cd00153
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
Ubiquitin domain of  RalGDS-like factor (RLF) and related proteins; cd00153
Glycosyltransferase family 6 comprises enzymes responsible for the production of the human ABO blood group antigens; cd02515
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Glycosyltransferase family 6 comprises enzymes responsible for the production of the human ABO blood group antigens; cd02515
Surfeit locus protein 6; pfam04935
Surfeit locus protein 5 subunit 22 of Mediator complex; pfam06179
Surfeit locus protein 5 subunit 22 of Mediator complex; pfam06179
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; cl00600
SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV). Cytochrome c oxidase (complex IV), the terminal electron-transferring...; cd06662
Surfeit locus protein 2 (SURF2); pfam05477
SURF4 family; pfam02077
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; COG0847
DEDDh 3'-5' exonuclease domain of RNA exonuclease 4, XPMC2, Interferon Stimulated Gene product of 20 kDa, and similar proteins; cd06144
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that...; cd04273
Thrombospondin type 1 repeats; smart00209
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that...; cd04273
Thrombospondin type 1 repeats; smart00209
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that...; cd04273
Thrombospondin type 1 repeats; smart00209
Uncharacterized conserved protein CG6151-P; smart01077
Uncharacterized conserved protein CG6151-P; cl10918
Uncharacterized conserved protein CG6151-P; smart01077
Uncharacterized conserved protein CG6151-P; cl10918
Sugar (and other) transporter; pfam00083
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Sugar (and other) transporter; pfam00083
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Protein of unknown function (DUF3522); pfam12036
Thrombospondin type 1 repeats; smart00209
ADAM-TS Spacer 1; pfam05986
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 domain; cl15278
Thrombospondin type 1 repeats; smart00209
PLAC (protease and lacunin) domain; pfam08686
Thrombospondin type 1 repeats; smart00209
ADAM-TS Spacer 1; pfam05986
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 domain; cl15278
Thrombospondin type 1 repeats; smart00209
PLAC (protease and lacunin) domain; pfam08686
DOMON-like domain of copper-dependent monooxygenases and related proteins; cd09631
DOMON domain; pfam03351
Copper type II ascorbate-dependent monooxygenase, N-terminal domain; pfam01082
Copper type II ascorbate-dependent monooxygenase, C-terminal domain; pfam03712
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
FAD dependent oxidoreductase; pfam01266
Glycine cleavage system T protein (aminomethyltransferase) [Amino acid transport and metabolism]; COG0404
Glycine cleavage T-protein C-terminal barrel domain; pfam08669
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
FAD dependent oxidoreductase; pfam01266
Glycine cleavage system T protein (aminomethyltransferase) [Amino acid transport and metabolism]; COG0404
Glycine cleavage T-protein C-terminal barrel domain; pfam08669
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
First Src homology 3 domain of VAV2 protein; cd11980
Src homology 2 (SH2) domain found in the Vav2 proteins; cd10406
C-terminal (or second) Src homology 3 domain of VAV2 protein; cd11977
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
First Src homology 3 domain of VAV2 protein; cd11980
Src homology 2 (SH2) domain found in the Vav2 proteins; cd10406
C-terminal (or second) Src homology 3 domain of VAV2 protein; cd11977
Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino...; cd05497
Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino...; cd05498
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Nuclear/hormone receptor activator site AF-1; pfam11825
DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers; cd06956
The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily; cd06943
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Collagen triple helix repeat (20 copies); pfam01391
Fibrillar collagens C-terminal domain; smart00038
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
Collagen triple helix repeat (20 copies); pfam01391
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
Neurogenesis glycoprotein; pfam12308
Olfactomedin-like domains; smart00284
Neurogenesis glycoprotein; pfam12308
Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; cd01425
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; cl11394
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Ion channel; pfam07885
Calcium-activated BK potassium channel alpha subunit; pfam03493
CAMSAP CH domain; pfam11971
Microtubule-binding calmodulin-regulated spectrin-associated; smart01051
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
XPC-binding domain; cl15287
BTB/POZ domain; pfam00651
The BEN domain is found in diverse animal proteins; smart01025
The first LIM domain of Lhx3b; cd09467
The second LIM domain of Lhx3-Lhx4 family; cd09376
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
The first LIM domain of Lhx3b; cd09467
The second LIM domain of Lhx3-Lhx4 family; cd09376
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
PDIa family, Quiescin-sulfhydryl oxidase (QSOX) subfamily; QSOX is a eukaryotic protein containing an N-terminal redox active TRX domain, similar to that of PDI, and a small C-terminal flavin adenine dinucleotide (FAD)-binding domain homologous to the...; cd02992
Erv1 / Alr family; pfam04777
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
GoLoco motif; pfam02188
GoLoco motif; pfam02188
LGN motif, putative GEFs specific for G-alpha GTPases; smart00390
GoLoco motif; pfam02188
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
GoLoco motif; pfam02188
LGN motif, putative GEFs specific for G-alpha GTPases; smart00390
GoLoco motif; pfam02188
GoLoco motif; pfam02188
LGN motif, putative GEFs specific for G-alpha GTPases; smart00390
GoLoco motif; pfam02188
DNL zinc finger; pfam05180
Caspase activation and recruitment domain of CARD9-like proteins; cd08809
Caspase activation and recruitment domain of CARD9-like proteins; cd08809
Myb-like DNA-binding domain; pfam13921
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
chromosome segregation protein SMC, common bacterial type; TIGR02168
chromosome segregation protein SMC, common bacterial type; TIGR02168
chromosome segregation protein SMC, common bacterial type; TIGR02168
Predicted Zn-dependent peptidases [General function prediction only]; COG0612
Insulinase (Peptidase family M16); pfam00675
Peptidase M16 inactive domain; pfam05193
Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Inositol polyphosphate-5-phosphatase E and related proteins; cd09095
Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16; cd09233
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Domain found in Notch and Lin-12; smart00004
LNR domain; pfam00066
LNR domain; pfam00066
NOTCH protein; pfam06816
NOTCH protein; pfam07684
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Domain of unknown function (DUF3454); pfam11936
EMI domain; pfam07546
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
EMI domain; pfam07546
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; COG0204
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; cd07989
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; cd07989
Pancreatitis induced protein 49 C terminal; pfam12260
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Uncharacterized protein conserved in bacteria with an aminopeptidase-like domain [General function prediction only]
GTPase SAR1 and related small G proteins [General function prediction only]
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
GTPase SAR1 and related small G proteins [General function prediction only]
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
GTPase SAR1 and related small G proteins [General function prediction only]
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
MYND finger; pfam01753
Janus/Ocnus family (Ocnus); pfam05005
Janus/Ocnus family (Ocnus); pfam05005
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
MAM domain; pfam00629
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cl02479
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Multiprotein bridging factor 1; pfam08523
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; cd00093
Multiprotein bridging factor 1; pfam08523
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; cd00093
Zinc finger, C3HC4 type (RING finger); pfam00097
TRAF-type zinc finger; pfam02176
Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the...; cd03778
F-box-like; pfam12937
FOG: WD40 repeat [General function prediction only]
WD domain, G-beta repeat; pfam00400
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
GST_N family, Chloride Intracellular Channel (CLIC) subfamily; composed of CLIC1-5, p64, parchorin and similar proteins. They are auto-inserting, self-assembling intracellular anion channels involved in a wide variety of functions including regulated...; cd03061
intracellular chloride channel protein; TIGR00862
C-terminal, alpha helical domain of Chloride Intracellular Channel 3; cd10299
ABC-2 family transporter protein; pfam12698
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
daunorubicin resistance ABC transporter ATP-binding subunit; TIGR01188
ABC-2 family transporter protein; pfam12698
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; COG1131
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
ABC-2 family transporter protein; pfam12698
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
daunorubicin resistance ABC transporter ATP-binding subunit; TIGR01188
ABC-2 family transporter protein; pfam12698
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; COG1131
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
Glycosyltransferase family 10 (fucosyltransferase); pfam00852
Neural proliferation differentiation control-1 protein (NPDC1); pfam06809
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Adenomatous polyposis coli tumour suppressor protein; pfam11414
UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc; cd04193
Glycosyl hydrolase family 47; pfam01532
Serine carboxypeptidase S28; cl15279
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor; cd06379
Receptor family ligand binding region; pfam01094
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Ligand-gated ion channel; pfam00060
Eukaryotic homologues of bacterial periplasmic substrate binding proteins; smart00079
Calmodulin-binding domain C0 of NMDA receptor NR1 subunit; pfam10562
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor; cd06379
Receptor family ligand binding region; pfam01094
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Ligand-gated ion channel; pfam00060
Eukaryotic homologues of bacterial periplasmic substrate binding proteins; smart00079
Calmodulin-binding domain C0 of NMDA receptor NR1 subunit; pfam10562
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor; cd06379
Receptor family ligand binding region; pfam01094
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Ligand-gated ion channel; pfam00060
Eukaryotic homologues of bacterial periplasmic substrate binding proteins; smart00079
Calmodulin-binding domain C0 of NMDA receptor NR1 subunit; pfam10562
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor; cd06379
Receptor family ligand binding region; pfam01094
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Ligand-gated ion channel; pfam00060
Eukaryotic homologues of bacterial periplasmic substrate binding proteins; smart00079
Calmodulin-binding domain C0 of NMDA receptor NR1 subunit; pfam10562
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR1, an essential channel-forming subunit of the NMDA receptor; cd06379
Receptor family ligand binding region; pfam01094
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Ligand-gated ion channel; pfam00060
Eukaryotic homologues of bacterial periplasmic substrate binding proteins; smart00079
Calmodulin-binding domain C0 of NMDA receptor NR1 subunit; pfam10562
Leucine rich repeat; pfam13855
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Cullin family; pfam00888
Cullin; smart00182
Anaphase promoting complex (APC) subunit 2; smart01013
Autophagy protein Apg6; pfam04111
PP1-regulatory protein, Phostensin N-terminal; pfam13916
Phostensin PP1-binding and SH3-binding region; pfam13914
Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; COG0369
Flavodoxin; pfam00258
NADPH cytochrome p450 reductase (CYPOR) serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via...; cd06207
Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; COG0369
Flavodoxin; pfam00258
NADPH cytochrome p450 reductase (CYPOR) serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via...; cd06207
Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; COG0369
Flavodoxin; pfam00258
NADPH cytochrome p450 reductase (CYPOR) serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via...; cd06207
Flavodoxin; pfam00258
FAD binding domain; pfam00667
Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; cl06868
Protein of unknown function (DUF2477); pfam10631
Ring finger domain; pfam13639
Phosphate:Na+ Symporter (PNaS) Family; TIGR01013
Na+/Pi-cotransporter; pfam02690
Na+/Pi-cotransporter; pfam02690
Phosphate:Na+ Symporter (PNaS) Family; TIGR01013
Na+/Pi-cotransporter; pfam02690
Na+/Pi-cotransporter; pfam02690
Phosphate:Na+ Symporter (PNaS) Family; TIGR01013
Na+/Pi-cotransporter; pfam02690
Na+/Pi-cotransporter; pfam02690
tubulin beta chain; Provisional
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02187
Protein of unknown function (DUF2475); pfam10629
Cofactor of BRCA1 (COBRA1); pfam06209
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
DEDDy 3'-5' exonuclease domain of Caenorhabditis elegans mut-7 and similar proteins; cd06146
Uncharacterized conserved protein [Function unknown]
Protein of unknown function DUF82; pfam01927
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
The PB1 domain is present in the p51 protein, a homolog of the p67 protein.  p51 plays an  important role in NADPH oxidase activation during phagosytosis. The PB1 domain is a modular domain mediating specific protein-protein interaction in many critical...; cd06411
Src Homology 3 domain superfamily; cl17036
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
The PB1 domain is present in the p51 protein, a homolog of the p67 protein.  p51 plays an  important role in NADPH oxidase activation during phagosytosis. The PB1 domain is a modular domain mediating specific protein-protein interaction in many critical...; cd06411
C-terminal Src Homology 3 domain of NADPH oxidase activator 1; cd12047
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
The PB1 domain is present in the p51 protein, a homolog of the p67 protein.  p51 plays an  important role in NADPH oxidase activation during phagosytosis. The PB1 domain is a modular domain mediating specific protein-protein interaction in many critical...; cd06411
Src Homology 3 domain superfamily; cl17036
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cl17037
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
Patatin-like phospholipase domain containing protein 6 and protein 7; cd07225
Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; COG1752
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
Patatin-like phospholipase domain containing protein 6 and protein 7; cd07225
Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; COG1752
Mitochondrial ribosomal protein L27; pfam09809
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
MYND finger; pfam01753
Arrestin (or S-antigen), N-terminal domain; pfam00339
Arrestin (or S-antigen), C-terminal domain; pfam02752
Ankyrin repeat; pfam00023
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13857
Ankyrin repeat; pfam00023
Pre-SET motif; pfam05033
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
tubulin beta chain; Provisional
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02187
PHD zinc finger; smart00249
Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene...; cd05492
The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions.  BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND...; cd05841
MYND finger; pfam01753
Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene...; cd05492
The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions.  BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND...; cd05841
MYND finger; pfam01753
Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene...; cd05492
The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions.  BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND...; cd05841
MYND finger; pfam01753
Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine; cl02556
The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions.  BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND...; cd05841
MYND finger; pfam01753
PHD zinc finger; smart00249
Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene...; cd05492
The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions.  BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND...; cd05841
PHD zinc finger; smart00249
Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene...; cd05492
The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions.  BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND...; cd05841
Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene...; cd05492
The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions.  BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND...; cd05841
DMAP1-binding Domain; pfam06464
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; COG0318
AMP-binding enzyme; pfam00501
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; COG0318
AMP-binding enzyme; pfam00501
La RNA-binding domain of La-related protein 5; cd08036
Predicted GTPase [General function prediction only]
Nucleolar GTP-binding protein (NOG); cd01897
NOGCT (NUC087) domain; pfam08155
Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; cl00447
isopentenyl-diphosphate delta-isomerase, type 1; TIGR02150
Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; cd02885
isopentenyl-diphosphate delta-isomerase, type 1; TIGR02150
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cl00054
tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase); smart00552
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent...; cd00764
6-phosphofructokinase, eukaryotic type; TIGR02478
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent...; cd00764
6-phosphofructokinase, eukaryotic type; TIGR02478
Predicted Zn-dependent peptidases, insulinase-like [General function prediction only]
Insulinase (Peptidase family M16); pfam00675
Peptidase M16 inactive domain; pfam05193
Peptidase M16C associated; pfam08367
Peptidase M16C associated; pfam08367
Peptidase M16 inactive domain; pfam05193
Predicted Zn-dependent peptidases, insulinase-like [General function prediction only]
Insulinase (Peptidase family M16); pfam00675
Peptidase M16 inactive domain; pfam05193
Peptidase M16C associated; pfam08367
Peptidase M16 inactive domain; pfam05193
Predicted Zn-dependent peptidases, insulinase-like [General function prediction only]
Insulinase (Peptidase family M16); pfam00675
Peptidase M16 inactive domain; pfam05193
Peptidase M16C associated; pfam08367
Peptidase M16 inactive domain; pfam05193
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Aldo/keto reductase family; pfam00248
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Aldo/keto reductase family; pfam00248
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cl00470
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cl00470
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Aldo/keto reductase family; pfam00248
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Aldo/keto reductase family; pfam00248
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Aldo/keto reductase family; pfam00248
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Aldo/keto reductase family; pfam00248
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Aldo/keto reductase family; pfam00248
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cl00470
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Aldo/keto reductase family; pfam00248
Agonist of corticotropin releasing factor R2, Urocortin-2; pfam11613
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02186
epsilon tubulin; Provisional
tubulin alpha chain; Provisional
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02186
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology (PH) domain; cd00821
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology (PH) domain; cd00821
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13857
Ankyrin repeats (many copies); pfam13857
Ankyrin repeat; pfam00023
SOCS (suppressors of cytokine signaling) box of ASB13-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system; cd03729
Protein of unknown function (DUF3699); pfam12480
Protein of unknown function (DUF3715); pfam12509
Protein of unknown function (DUF3715); pfam12509
Protein of unknown function (DUF3699); pfam12480
GDP dissociation inhibitor; pfam00996
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
GDP dissociation inhibitor; pfam00996
rab-GDP dissociation inhibitor; Provisional
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
F-box-like; pfam12937
Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; COG0210
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Family description; pfam13538
F-box-like; pfam12937
Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; COG0210
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Family description; pfam13538
F-box-like; pfam12937
Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; COG0210
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Family description; pfam13538
F-box-like; pfam12937
Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; COG0210
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Family description; pfam13538
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cl00043
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
glycine rich nucleic binding domain; smart00443
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
glycine rich nucleic binding domain; smart00443
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
6-phosphofructo-2-kinase; pfam01591
Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; cd07067
6-phosphofructo-2-kinase; pfam01591
Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; cd07067
C2 domain; cl14603
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
C2 domain; cl14603
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, Novel Protein Kinase C theta; cd05619
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Protein of unknown function (DUF3588); pfam12140
SAM domain of Scm-like-4MBT1,2 proteins of Polycomb group; cd09581
Sterile alpha motif; smart00454
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Protein of unknown function (DUF3588); pfam12140
SAM domain of Scm-like-4MBT1,2 proteins of Polycomb group; cd09581
Sterile alpha motif; smart00454
Vault protein inter-alpha-trypsin domain; pfam08487
vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to...; cd01461
Inter-alpha-trypsin inhibitor heavy chain C-terminus; pfam06668
vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to...; cd01461
Inter-alpha-trypsin inhibitor heavy chain C-terminus; pfam06668
Vault protein inter-alpha-trypsin domain; cl02699
vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to...; cd01461
Vault protein Inter-alpha-Trypsin domain; smart00609
vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to...; cd01461
Inter-alpha-trypsin inhibitor heavy chain C-terminus; pfam06668
Zinc-finger of C2H2 type; pfam12874
Domain of Kin17 curved DNA-binding protein; pfam10357
F0F1 ATP synthase subunit gamma; Provisional
ATP synthase, F1 gamma subunit; TIGR01146
F0F1 ATP synthase subunit gamma; Provisional
ATP synthase, F1 gamma subunit; TIGR01146
Bromodomain transcription factors and PHD domain containing proteins; smart00576
PHD zinc finger; smart00249
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C; cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C; cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C; cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C; cd00202
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
enoyl-CoA hydratase; Validated
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; cd06558
Middle domain of eukaryotic initiation factor 4G (eIF4G); smart00543
hypothetical protein; Provisional
Middle domain of eukaryotic initiation factor 4G (eIF4G); smart00543
Middle domain of eukaryotic initiation factor 4G (eIF4G); smart00543
Up-frameshift suppressor 2; pfam04050
Middle domain of eukaryotic initiation factor 4G (eIF4G); smart00543
hypothetical protein; Provisional
Middle domain of eukaryotic initiation factor 4G (eIF4G); smart00543
Middle domain of eukaryotic initiation factor 4G (eIF4G); smart00543
Up-frameshift suppressor 2; pfam04050
2-oxoglutarate dehydrogenase E1 component; Reviewed; PRK09404
Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; cd02016
Transketolase, pyrimidine binding domain; pfam02779
Sec61 alpha  subunit; Provisional
Plug domain of Sec61p; pfam10559
SecY translocase; pfam00344
Sec61 alpha  subunit; Provisional
Plug domain of Sec61p; pfam10559
SecY translocase; pfam00344
Sec61 alpha  subunit; Provisional
Plug domain of Sec61p; pfam10559
SecY translocase; pfam00344
ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; cd03424
D123; pfam07065
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Septum formation initiator; cl11433
NF-kappa-B essential modulator NEMO; pfam11577
polyubiquitin binding domain of NEMO and related proteins; cd09803
NF-kappa-B essential modulator NEMO; pfam11577
polyubiquitin binding domain of NEMO and related proteins; cd09803
NF-kappa-B essential modulator NEMO; pfam11577
polyubiquitin binding domain of NEMO and related proteins; cd09803
NF-kappa-B essential modulator NEMO; pfam11577
polyubiquitin binding domain of NEMO and related proteins; cd09803
Primase zinc finger; pfam09329
Mcm10 replication factor; pfam09332
Primase zinc finger; pfam09329
Mcm10 replication factor; pfam09332
Phytanoyl-CoA dioxygenase (PhyH); pfam05721
Phytanoyl-CoA dioxygenase (PhyH); pfam05721
Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; cd02195
selenium donor protein; TIGR00476
Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; cd02195
Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; cd02195
The BEN domain is found in diverse animal proteins; smart01025
The BEN domain is found in diverse animal proteins; smart01025
Splicing Factor Motif, present in Prp18 and Pr04; smart00500
Prp18 domain; pfam02840
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
Domain of unknown function (DUF3338); pfam11819
Protein of unknown function (DUF1151); pfam06625
Degradation arginine-rich protein for mis-folding; pfam10208
Nucleotide-binding domain of human HSPA14 and similar proteins; cd10238
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Pre-SET motif; pfam05033
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Pre-SET motif; pfam05033
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Pre-SET motif; pfam05033
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Beta-lactamase superfamily domain; pfam12706
DNA repair metallo-beta-lactamase; pfam07522
DNA repair metallo-beta-lactamase; pfam07522
DNA repair metallo-beta-lactamase; pfam07522
DNA repair metallo-beta-lactamase; pfam07522
Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; COG3208
Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; COG3208
Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a...; cd00435
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; pfam01248
Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain; pfam01233
Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain; pfam02799
Uncharacterized protein family UPF0560; pfam10577
Integrin alpha (beta-propellor repeats); smart00191
Integrin alpha (beta-propellor repeats); smart00191
Family description; pfam13517
Integrin alpha (beta-propellor repeats); smart00191
Family description; pfam13517
Integrin alpha (beta-propellor repeats); smart00191
Integrin alpha; pfam08441
Integrin alpha cytoplasmic region; pfam00357
Domain of unknown function (DUF4205); pfam13898
Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; cd00530
Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; cd00530
Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; cd00530
Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; cd00530
Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; cd00530
C1q domain; pfam00386
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
EGF domain; pfam12947
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; cd00315
DNA-methyltransferase (dcm); TIGR00675
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
Intermediate filament head (DNA binding) region; pfam04732
Intermediate filament protein; pfam00038
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Protein tyrosine phosphatase-like protein, PTPLA; pfam04387
VHS domain family, STAM subfamily; members include STAM (Signal Transducing Adaptor Molecule), EAST (EGFR-associated protein with SH3 and TAM domains) and Hbp (Hrs-binding protein). Collectively, they are referred to as STAM. All STAMs have at their...; cd03568
Src homology 3 domain of Signal Transducing Adaptor Molecules; cd11820
Ricin-type beta-trefoil; smart00458
Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; cd00161
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and...; cd00062
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
C-type lectin (CTL) or carbohydrate-recognition domain (CRD); smart00034
ZIP Zinc transporter; pfam02535
Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]
ZIP Zinc transporter; pfam02535
Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]
Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2; cd12040
Guanylate kinase; pfam00625
Guanylate kinase homologues; smart00072
Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2; cd12040
Guanylate kinase; pfam00625
Guanylate kinase homologues; smart00072
Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2; cd12040
Guanylate kinase; pfam00625
Guanylate kinase homologues; smart00072
Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2; cd12040
Guanylate kinase; pfam00625
Guanylate kinase homologues; smart00072
Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2; cd12040
Guanylate kinase; pfam00625
Guanylate kinase homologues; smart00072
Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2; cd12040
Guanylate kinase; pfam00625
Guanylate kinase homologues; smart00072
Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2; cd12040
Guanylate kinase; pfam00625
Guanylate kinase homologues; smart00072
Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2; cd12040
Guanylate kinase; pfam00625
Guanylate kinase homologues; smart00072
Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2; cd12040
Guanylate kinase; pfam00625
Guanylate kinase homologues; smart00072
Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; smart00359
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Arf-like 5 (Arl5) and 8 (Arl8) GTPases; cd04153
GTPase SAR1 and related small G proteins [General function prediction only]
Nidogen-like; cl02648
Plexin repeat; pfam01437
The LIM domain of LIM and SH3 Protein (LASP); cd09447
The Nebulin repeat is present also in Las1; smart00227
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; cl11595
C-terminal Src Homology 3 domain of Nebulette and LIM-nebulette (or Lasp2); cd11935
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; cl11595
Nebulin repeat; pfam00880
The Nebulin repeat is present also in Las1; smart00227
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; pfam00880
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; cl11595
Nebulin repeat; cl11595
Nebulin repeat; cl11595
Nebulin repeat; pfam00880
Nebulin repeat; pfam00880
C-terminal Src Homology 3 domain of Nebulette and LIM-nebulette (or Lasp2); cd11935
The LIM domain of LIM and SH3 Protein (LASP); cd09447
The Nebulin repeat is present also in Las1; smart00227
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; cl11595
SKI/SNO/DAC family; pfam02437
PHD-finger; pfam13831
PHD-zinc-finger like domain; pfam13832
PHD zinc finger; smart00249
PHD-finger; pfam13831
PHD-zinc-finger like domain; pfam13832
PHD zinc finger; smart00249
PHD-finger; pfam13831
PHD-finger; pfam13831
PHD-finger; pfam13831
Putative binding domain; pfam13900
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
Borna disease virus P40 protein; pfam06407
HCaRG protein; pfam07258
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
COMM_Domain containing protein 3. The COMM Domain is found at the C-terminus of a variety of proteins; presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in protein-protein interactions. Several...; cd04751
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
HEAT-like repeat; pfam13513
HEAT-like repeat; pfam13513
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
HEAT-like repeat; pfam13513
HEAT-like repeat; pfam13513
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
HEAT-like repeat; pfam13513
HEAT-like repeat; pfam13513
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
HEAT-like repeat; pfam13513
HEAT-like repeat; pfam13513
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Phosphatidylinositol phosphate kinases; smart00330
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
HEAT repeats; pfam13646
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
HEAT repeats; pfam13646
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Transglutaminase-like superfamily; cl10469
methionine sulfoxide reductase B; Provisional
SelR domain; pfam01641
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
OTU-like cysteine protease; pfam02338
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Pleckstrin homology (PH) domain; cd00821
RhoGAP_ARHGAP21: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the...; cd04395
GTPase-activator protein for Rho-like GTPases; smart00324
Phosphoribosyl transferase (PRT)-type I domain; cd06223
Calmodulin-binding; pfam13864
Calmodulin-binding; pfam13864
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; cd00464
Shikimate kinase; pfam01202
Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants, cyanobacteria; cd01560
Pyridoxal-phosphate dependent enzyme; pfam00291
7 transmembrane sweet-taste receptor of 3 GCPR; pfam00003
Catalytic domain of the Protein Serine/Threonine Kinase, Class IIIA myosin; cd06638
Serine/Threonine protein kinases, catalytic domain; smart00220
Myosin. Large ATPases; smart00242
Myosin motor domain, type III myosins. Myosin III has been shown to play a role in  the vision process in insects and in hearing in mammals. Myosin III, an unconventional myosin, does not form dimers. This catalytic (head) domain has ATPase activity and...; cd01379
Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; cl00286
IQ calmodulin-binding motif; cl15479
Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]; COG0076
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; cd06450
Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]; COG0076
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; cd06450
RA (RAS-associated like) domain of Grb7; cd01787
Pleckstrin homology-like domain; cl00273
geranyl diphosphate synthase
Trans-Isoprenyl Diphosphate Synthases, head-to-tail; cd00685
Src homology 3 domain of Abl Interactor 1; cd11971
Abl-interactor HHR; pfam07815
Src homology 3 domain of Abl Interactor 1; cd11971
Abl-interactor HHR; pfam07815
Src homology 3 domain of Abl Interactor 1; cd11971
Abl-interactor HHR; pfam07815
Src homology 3 domain of Abl Interactor 1; cd11971
Abl-interactor HHR; pfam07815
Src homology 3 domain of Abl Interactor 1; cd11971
Abl-interactor HHR; pfam07815
Src homology 3 domain of Abl Interactor 1; cd11971
Abl-interactor HHR; pfam07815
Src homology 3 domain of Abl Interactor 1; cd11971
Abl-interactor HHR; pfam07815
Src homology 3 domain of Abl Interactor 1; cd11971
Abl-interactor HHR; pfam07815
Src homology 3 domain of Abl Interactor 1; cd11971
Abl-interactor HHR; pfam07815
Src homology 3 domain of Abl Interactor 1; cd11971
Abl-interactor HHR; pfam07815
Src homology 3 domain of Abl Interactor 1; cd11971
Abl-interactor HHR; pfam07815
Src homology 3 domain of Abl Interactor 1; cd11971
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ATPase involved in DNA repair [DNA replication, recombination, and repair]; COG0419
Domain of unknown function (DUF3496); pfam12001
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ATPase involved in DNA repair [DNA replication, recombination, and repair]; COG0419
Domain of unknown function (DUF3496); pfam12001
ATP-dependent metalloprotease FtsH; TIGR01241
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Peptidase family M41; pfam01434
ATP-dependent metalloprotease FtsH; TIGR01241
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Peptidase family M41; pfam01434
ATP-dependent metalloprotease FtsH; TIGR01241
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Peptidase family M41; pfam01434
Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine-like kinase; cd05610
Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; COG0515
Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine-like kinase; cd05610
Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; COG0515
Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine-like kinase; cd05610
Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; COG0515
Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a...; cd00435
Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a...; cd00435
Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a...; cd00435
Patched family; pfam02460
Sterol-sensing domain of SREBP cleavage-activation; pfam12349
Rab GTPase family 18 (Rab18); cd01863
Rab GTPase family 18 (Rab18); cd01863
Rab GTPase family 18 (Rab18); cd01863
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Rab GTPase family 18 (Rab18); cd01863
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
HEAT repeats; pfam13646
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
HEAT repeats; pfam13646
domain in receptor targeting proteins Lin-2 and Lin-7; smart00569
domain in receptor targeting proteins Lin-2 and Lin-7; smart00569
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain of Membrane Protein, Palmitoylated 7 (or MAGUK p55 subfamily member 7); cd12033
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain; pfam06211
C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have...; cd00119
identified by homology and localization studies
identified by homology and localization studies
dominant nuclear localization signal identifien by homology and localization studies
Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins; cd11289
Tandemly repeated domains found in gelsolin, severin, villin, and related proteins; cd11280
Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins; cd11293
Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins; cd11288
Actin depolymerization factor/cofilin- and gelsolin-like domains; cl15697
Villin headpiece domain; pfam02209
identified by homology
identified by homology
identified by homology and localization studies
identified by homology and localization studies
dominant nuclear localization signal identified by homology and localization studies
Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins; cd11289
Tandemly repeated domains found in gelsolin, severin, villin, and related proteins; cd11280
Gelsolin sub-domain 4-like domain found in gelsolin, severin, villin, and related proteins; cd11293
Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins; cd11288
Actin depolymerization factor/cofilin- and gelsolin-like domains; cl15697
Villin headpiece domain; pfam02209
Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases; cd05402
Cid1 family poly A polymerase; pfam03828
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have...; cd00119
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
zinc finger; smart00355
Zinc-finger double domain; pfam13465
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
zinc finger; smart00355
Zinc-finger double domain; pfam13465
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
zinc finger; smart00355
Zinc-finger double domain; pfam13465
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
zinc finger; smart00355
Zinc-finger double domain; pfam13465
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
zinc finger; smart00355
Zinc-finger double domain; pfam13465
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
zinc finger; smart00355
Zinc-finger double domain; pfam13465
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Src Homology 3 domain of Rho GTPase-activating protein 12; cd12070
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Pleckstrin homology (PH) domain; cd00821
RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains; cd04403
GTPase-activator protein for Rho-like GTPases; smart00324
Src Homology 3 domain of Rho GTPase-activating protein 12; cd12070
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Pleckstrin homology (PH) domain; cd00821
RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains; cd04403
GTPase-activator protein for Rho-like GTPases; smart00324
Src Homology 3 domain of Rho GTPase-activating protein 12; cd12070
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Pleckstrin homology (PH) domain; cd00821
RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains; cd04403
GTPase-activator protein for Rho-like GTPases; smart00324
Src Homology 3 domain of Rho GTPase-activating protein 12; cd12070
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Pleckstrin homology (PH) domain; cd00821
RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains; cd04403
GTPase-activator protein for Rho-like GTPases; smart00324
Src Homology 3 domain of Rho GTPase-activating protein 12; cd12070
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Pleckstrin homology (PH) domain; cd00821
RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains; cd04403
GTPase-activator protein for Rho-like GTPases; smart00324
Src Homology 3 domain of Rho GTPase-activating protein 12; cd12070
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Pleckstrin homology (PH) domain; cd00821
RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains; cd04403
GTPase-activator protein for Rho-like GTPases; smart00324
Kinesin motor domain, kinesin heavy chain (KHC) or KIF5-like subgroup. Members of this group have been associated with organelle transport. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Kinesins are...; cd01369
Kinesin motor, catalytic domain. ATPase; smart00129
Enhancer of polycomb-like; pfam10513
Enhancer of Polycomb C-terminus; pfam06752
Integrin, beta chain; pfam00362
Integrin beta tail domain; pfam07965
Integrin beta cytoplasmic domain; pfam08725
Integrin, beta chain; pfam00362
Integrin beta tail domain; pfam07965
Integrin beta cytoplasmic domain; pfam08725
Integrin, beta chain; pfam00362
Integrin beta tail domain; pfam07965
Integrin beta cytoplasmic domain; pfam08725
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Domain of unknown function (DUF3481); pfam11980
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Domain of unknown function (DUF3481); pfam11980
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Domain of unknown function (DUF3481); pfam11980
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Domain of unknown function (DUF3534); pfam12053
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Domain of unknown function (DUF3534); pfam12053
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Domain of unknown function (DUF3534); pfam12053
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Domain of unknown function (DUF3534); pfam12053
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Domain of unknown function (DUF3534); pfam12053
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Domain of unknown function (DUF3534); pfam12053
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Domain of unknown function (DUF3534); pfam12053
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Domain of unknown function (DUF3534); pfam12053
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Domain of unknown function (DUF3534); pfam12053
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Domain of unknown function (DUF3534); pfam12053
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Domain of unknown function (DUF3534); pfam12053
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Cullin family; pfam00888
Cullin; smart00182
Cullin protein neddylation domain; pfam10557
Cullin family; pfam00888
Cullin; smart00182
Cullin protein neddylation domain; pfam10557
Cullin family; pfam00888
Cullin; smart00182
Cullin protein neddylation domain; pfam10557
Cullin family; pfam00888
Cullin; smart00182
Cullin protein neddylation domain; pfam10557
pKID domain; pfam02173
bZIP transcription factor; pfam00170
pKID domain; pfam02173
bZIP transcription factor; pfam00170
pKID domain; pfam02173
bZIP transcription factor; pfam00170
pKID domain; pfam02173
bZIP transcription factor; pfam00170
pKID domain; pfam02173
bZIP transcription factor; pfam00170
pKID domain; pfam02173
pKID domain; pfam02173
bZIP transcription factor; pfam00170
pKID domain; pfam02173
bZIP transcription factor; pfam00170
pKID domain; pfam02173
bZIP transcription factor; pfam00170
Putative binding domain; pfam13900
pKID domain; pfam02173
pKID domain; pfam02173
bZIP transcription factor; pfam00170
pKID domain; pfam02173
bZIP transcription factor; pfam00170
pKID domain; pfam02173
bZIP transcription factor; pfam00170
bZIP transcription factor; pfam00170
bZIP transcription factor; pfam00170
bZIP transcription factor; pfam00170
bZIP transcription factor; pfam00170
bZIP transcription factor; pfam00170
bZIP transcription factor; pfam00170
bZIP transcription factor; pfam00170
bZIP transcription factor; pfam00170
bZIP transcription factor; pfam00170
bZIP transcription factor; pfam00170
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cl00050
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cl00050
Connexin; cl02435
Gap junction channel protein cysteine-rich domain; pfam10582
Cysteine-rich Wnt-binding domain (CRD) of the frizzled 8 (Fz8) receptor; cd07461
Frizzled/Smoothened family membrane region; pfam01534
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Bms1, an essential GTPase, promotes assembly of preribosomal RNA processing complexes; cd01882
AARP2CN (NUC121) domain; smart00785
Protein of unknown function (DUF663); pfam04950
Cadherin tandem repeat domain; cd11304
Catalytic domain of the Protein Tyrosine Kinase, REarranged during Transfection protein; cd05045
Protein tyrosine kinase; pfam07714
Cadherin tandem repeat domain; cd11304
Catalytic domain of the Protein Tyrosine Kinase, REarranged during Transfection protein; cd05045
Protein tyrosine kinase; pfam07714
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; cl11394
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNPHF zinc finger; pfam08080
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNPHF zinc finger; pfam08080
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNPHF zinc finger; pfam08080
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNPHF zinc finger; pfam08080
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNPHF zinc finger; pfam08080
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNPHF zinc finger; pfam08080
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Chemokine_CXC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members...; cd00273
Chemokine_CXC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members...; cd00273
Chemokine_CXC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members...; cd00273
Chemokine_CXC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members...; cd00273
Ubiquitin-like proteins; cl00155
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and...; cd01753
Lipoxygenase; pfam00305
PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and...; cd01753
Lipoxygenase; pfam00305
PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and...; cd01753
Lipoxygenase; pfam00305
The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins; smart00744
Tripartite ATP-independent periplasmic transporters, DctQ component; pfam04290
The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins; smart00744
Tripartite ATP-independent periplasmic transporters, DctQ component; pfam04290
The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins; smart00744
Tripartite ATP-independent periplasmic transporters, DctQ component; pfam04290
ubiquitin-like domain of AN1; cd01802
Ubiquitin homologues; smart00213
AN1-like Zinc finger; smart00154
ubiquitin-like domain of AN1; cd01802
Ubiquitin homologues; smart00213
AN1-like Zinc finger; smart00154
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
Putative GTPase activating protein for Arf; pfam01412
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein-tyrosine phosphatase; pfam00102
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatase, catalytic domain; smart00194
C2A domain first repeat present in Synaptotagmins 15 and 17; cd08390
C2 domain; cl14603
C2A domain first repeat present in Synaptotagmins 15 and 17; cd08390
C2 domain second repeat present in Synaptotagmin 15; cd08409
7 transmembrane receptor (rhodopsin family); pfam00001
Annexin; pfam00191
Annexin; pfam00191
Annexin repeats; smart00335
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Annexin repeats; smart00335
Annexin; pfam00191
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
Putative GTPase activating protein for Arf; pfam01412
Ankyrin repeats (3 copies); pfam12796
Annexin; pfam00191
Annexin; pfam00191
Annexin repeats; smart00335
Annexin; pfam00191
Zinc finger, C2H2 type; cl15478
Interphotoreceptor retinoid-binding protein; serine protease family S41; cd07563
Interphotoreceptor retinoid-binding protein; serine protease family S41; cd07563
Interphotoreceptor retinoid-binding protein; serine protease family S41; cd07563
Interphotoreceptor retinoid-binding protein; serine protease family S41; cd07563
TGF-beta propeptide; pfam00688
Transforming growth factor-beta (TGF-beta) family; smart00204
TGF-beta propeptide; pfam00688
Transforming growth factor-beta (TGF-beta) family; smart00204
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein-tyrosine phosphatase; pfam00102
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatase, catalytic domain; smart00194
kinase non-catalytic C-lobe domain; smart00750
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM C-terminal PH-like domain; pfam09380
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase; cd07850
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase; cd07850
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase; cd07850
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Serine/Threonine Kinase, c-Jun N-terminal Kinase; cd07850
Serine/Threonine protein kinases, catalytic domain; smart00220
Pleckstrin homology (PH) domain; cd00821
RhoGAP_ARHGAP22_24_25:  GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been...; cd04390
GTPase-activator protein for Rho-like GTPases; smart00324
TATA Binding Protein (TBP) Associated Factor 4 (TAF4) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex; cl05005
Domain of unknown function (DUF4200); pfam13863
Pleckstrin homology (PH) domain; cd00821
RhoGAP_ARHGAP22_24_25:  GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been...; cd04390
GTPase-activator protein for Rho-like GTPases; smart00324
TATA Binding Protein (TBP) Associated Factor 4 (TAF4) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex; cl05005
Domain of unknown function (DUF4200); pfam13863
Pleckstrin homology (PH) domain; cd00821
RhoGAP_ARHGAP22_24_25:  GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been...; cd04390
GTPase-activator protein for Rho-like GTPases; smart00324
TATA Binding Protein (TBP) Associated Factor 4 (TAF4) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex; cl05005
Domain of unknown function (DUF4200); pfam13863
RhoGAP_ARHGAP22_24_25:  GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been...; cd04390
GTPase-activator protein for Rho-like GTPases; smart00324
TATA Binding Protein (TBP) Associated Factor 4 (TAF4) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex; cl05005
Domain of unknown function (DUF4200); pfam13863
BEACH (Beige and Chediak-Higashi) domains, implicated in membrane trafficking,  are present in a family of proteins conserved throughout eukaryotes. This group contains human lysosomal trafficking regulator (LYST), LPS-responsive and beige-like anchor; cd06071
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Leucine rich repeat; pfam13855
Immunoglobulin V-set domain; pfam07686
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
OAR domain; pfam03826
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Transposase IS4; pfam13843
DDE_Tnp_1-like zinc-ribbon; pfam13842
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Major Facilitator Superfamily; pfam07690
Choline/Carnitine o-acyltransferase; pfam00755
Choline/Carnitine o-acyltransferase; pfam00755
Choline/Carnitine o-acyltransferase; pfam00755
Choline/Carnitine o-acyltransferase; pfam00755
Choline/Carnitine o-acyltransferase; pfam00755
Choline/Carnitine o-acyltransferase; pfam00755
Choline/Carnitine o-acyltransferase; pfam00755
Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; cl00281
2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes [Energy production and conversion]; COG0567
Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; cd02016
Transketolase, pyrimidine binding domain; pfam02779
2-oxoglutarate dehydrogenase E1 component; Reviewed; PRK09404
Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; cd02016
Transketolase, pyrimidine binding domain; pfam02779
2-oxoglutarate dehydrogenase E1 component; Reviewed; PRK09404
Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; cd02016
Transketolase, pyrimidine binding domain; pfam02779
Poly (ADP-ribose) glycohydrolase (PARG); pfam05028
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
Putative GTPase activating protein for Arf; pfam01412
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
Putative GTPase activating protein for Arf; pfam01412
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Beta-microseminoprotein (PSP-94); pfam05825
Nuclear coactivator; pfam12489
Nuclear coactivator; pfam12489
Nuclear coactivator; pfam12489
Nuclear coactivator; pfam12489
Nuclear coactivator; pfam12489
Nuclear coactivator; pfam12489
Nuclear coactivator; pfam12489
Nuclear coactivator; pfam12489
Nuclear coactivator; pfam12489
Nuclear coactivator; pfam12489
mitochondrial import inner membrane translocase subunit tim23; TIGR00983
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
Putative GTPase activating protein for Arf; pfam01412
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Neutral/alkaline non-lysosomal ceramidase; pfam04734
Neutral/alkaline non-lysosomal ceramidase; pfam04734
SAM domain of sphingomyelin synthase; cd09514
Sterile alpha motif; smart00454
PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; cd01610
Neutral/alkaline non-lysosomal ceramidase; cl04712
heterogeneous nuclear ribonucleoprotein R, Q family; TIGR01648
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
heterogeneous nuclear ribonucleoprotein R, Q family; TIGR01648
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
heterogeneous nuclear ribonucleoprotein R, Q family; TIGR01648
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
heterogeneous nuclear ribonucleoprotein R, Q family; TIGR01648
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
heterogeneous nuclear ribonucleoprotein R, Q family; TIGR01648
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
heterogeneous nuclear ribonucleoprotein R, Q family; TIGR01648
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, cGMP-dependent protein kinase; cd05572
Extension to Ser/Thr-type protein kinases; smart00133
Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I beta; cd12086
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, cGMP-dependent protein kinase; cd05572
Extension to Ser/Thr-type protein kinases; smart00133
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Hinge domain of cleavage stimulation factor subunit 2; pfam14327
Transcription termination and cleavage factor C-terminal; pfam14304
Dickkopf N-terminal cysteine-rich region; pfam04706
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
cell division protein MukB; Provisional; PRK04863
cell division protein MukB; Provisional; PRK04863
Inositol polyphosphate kinase; pfam03770
Inositol polyphosphate kinase; cl12283
CDGSH-type zinc finger. Function unknown; smart00704
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]; COG5648
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
K homology RNA-binding domain_vigilin_like.  The vigilin family is a large and extended family of multiple KH-domain proteins, including vigilin, also called high density lipoprotein binding protien (HBP), fungal Scp160 and bicaudal-C. Yeast Scp160p has...; cd02394
K homology RNA-binding domain_vigilin_like.  The vigilin family is a large and extended family of multiple KH-domain proteins, including vigilin, also called high density lipoprotein binding protien (HBP), fungal Scp160 and bicaudal-C. Yeast Scp160p has...; cd02394
K homology RNA-binding domain_vigilin_like.  The vigilin family is a large and extended family of multiple KH-domain proteins, including vigilin, also called high density lipoprotein binding protien (HBP), fungal Scp160 and bicaudal-C. Yeast Scp160p has...; cd02394
SAM domain of BICC1 (bicaudal) subfamily; cd09520
Sterile alpha motif; smart00454
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Uncharacterized conserved protein H4 (DUF2046); pfam09755
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13857
Domain present in ZO-1 and Unc5-like netrin receptors; smart00218
Death domain of Ankyrin-3; cd08803
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13857
Domain present in ZO-1 and Unc5-like netrin receptors; smart00218
Death domain of Ankyrin-3; cd08803
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13857
Domain present in ZO-1 and Unc5-like netrin receptors; smart00218
Death domain of Ankyrin-3; cd08803
Domain present in ZO-1 and Unc5-like netrin receptors; smart00218
Death domain of Ankyrin-3; cd08803
cyclin-dependent kinase A; Provisional
Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 1 from higher eukaryotes-like; cd07861
cyclin-dependent kinase A; Provisional
Protein Kinases, catalytic domain; cl09925
Protein Kinases, catalytic domain; cl09925
Protein Kinases, catalytic domain; cl09925
GTPase SAR1 and related small G proteins [General function prediction only]
RhoBTB protein is an atypical member of the Rho family of small GTPases; cd01873
BTB/POZ domain; cl02518
Broad-Complex, Tramtrack and Bric a brac; smart00225
Broad-Complex, Tramtrack and Bric a brac; smart00225
GTPase SAR1 and related small G proteins [General function prediction only]
RhoBTB protein is an atypical member of the Rho family of small GTPases; cd01873
BTB/POZ domain; cl02518
Broad-Complex, Tramtrack and Bric a brac; smart00225
Broad-Complex, Tramtrack and Bric a brac; smart00225
Transmembrane protein 26; pfam09772
BRIGHT, ARID (A/T-rich interaction domain) domain; smart00501
BRIGHT, ARID (A/T-rich interaction domain) domain; smart00501
Rho effector or protein kinase C-related kinase homology region 1 homologues; smart00742
Cell division protein anillin; pfam08174
Pleckstrin homology (PH) domain; cd00821
AAA domain; pfam13654
AAA domain; pfam13654
AAA domain; pfam13654
Protein of unknown function (DUF1637); pfam07847
Domain of unknown function (DUF3446); pfam11928
contains 3 tandem zinc fingers of the C2H2-type
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Domain of unknown function (DUF3446); pfam11928
contains 3 tandem zinc fingers of the C2H2-type
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Domain of unknown function (DUF3446); pfam11928
contains 3 tandem zinc fingers of the C2H2-type
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Domain of unknown function (DUF3446); pfam11928
contains 3 tandem zinc fingers of the C2H2-type
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
MIT (microtubule interacting and transport) domain; pfam04212
Domain of unknown function (DUF1875); pfam08961
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; cl15814
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; cl15814
TB2/DP1, HVA22 family; pfam03134
Vinculin family; pfam01044
Vinculin family; pfam01044
Leucine rich repeat N-terminal domain; smart00013
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]; COG0484
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
NAD-dependent deacetylase; Provisional
SIRT1: Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2...; cd01408
SIRT1: Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2...; cd01408
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Phenazine biosynthesis-like protein; pfam02567
Phenazine biosynthesis-like protein; pfam02567
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RUN domain; pfam02759
Protein of unknown function (DUF972); pfam06156
PspA/IM30 family; pfam04012
FYVE zinc finger; pfam01363
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
RUN domain; cl02689
Protein of unknown function (DUF972); pfam06156
DNA replication factor Dna2; pfam08696
CRISPR/Cas system-associated protein Cas4; cl00641
AAA domain; pfam13086
AAA domain; pfam13087
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
CXXC zinc finger domain; pfam02008
Oxygenase domain of the 2OGFeDO superfamily; pfam12851
Oxygenase domain of the 2OGFeDO superfamily; pfam12851
S1-like; pfam14444
DBC1; pfam14443
SAP domain; pfam02037
Winged helix Storkhead-box1 domain; pfam10264
Winged helix Storkhead-box1 domain; pfam10264
Winged helix Storkhead-box1 domain; pfam10264
Winged helix Storkhead-box1 domain; pfam10264
Winged helix Storkhead-box1 domain; pfam10264
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
DEAD-like helicases superfamily; smart00487
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
GUCT (NUC152) domain; pfam08152
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
DEAD-like helicases superfamily; smart00487
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
GUCT (NUC152) domain; pfam08152
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
DEAD-like helicases superfamily; smart00487
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
GUCT (NUC152) domain; pfam08152
KIF-1 binding protein C terminal; pfam12309
Serglycin; pfam04360
Vacuolar protein sorting-associated protein 26; pfam03643
Vacuolar protein sorting-associated protein 26; pfam03643
Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; COG0513
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Mitochondrial degradasome RNA helicase subunit C terminal; pfam12513
hexokinase
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Hexokinase; pfam03727
hexokinase; Provisional
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Hexokinase; pfam03727
hexokinase; Provisional
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Hexokinase; pfam03727
hexokinase; Provisional
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Hexokinase; pfam03727
hexokinase; Provisional
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Hexokinase; pfam03727
hexokinase; Provisional
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Hexokinase; pfam03727
hexokinase; Provisional
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Hexokinase; pfam03727
hexokinase; Provisional
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Hexokinase; pfam03727
hexokinase; Provisional
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Hexokinase; pfam03727
hexokinase; Provisional
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Hexokinase; pfam03727
hexokinase; Provisional
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Hexokinase; pfam03727
hexokinase; Provisional
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Hexokinase; pfam03727
7 transmembrane receptor (rhodopsin family); pfam00001
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), penumbra_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment...; cd03158
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cd00074
Macro domain, Macro_H2A_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose...; cd02904
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; COG1252
Pyridine nucleotide-disulphide oxidoreductase; pfam00070
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; COG1252
Pyridine nucleotide-disulphide oxidoreductase; pfam00070
Trypsin-like peptidase domain; pfam13365
Sar1 is an essential component of COPII vesicle coats; cd00879
GTPase SAR1 and related small G proteins [General function prediction only]
Sar1 is an essential component of COPII vesicle coats; cd00879
GTPase SAR1 and related small G proteins [General function prediction only]
Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; cd00412
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Eukaryotic translation initiation factor 4E binding protein (EIF4EBP); pfam05456
TGF-beta propeptide; pfam00688
Transforming growth factor-beta (TGF-beta) family; smart00204
Protein tyrosine phosphatase, catalytic domain motif; smart00404
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cl00053
membrane-attack complex / perforin; smart00457
C2 domain of Perforin; cd04032
membrane-attack complex / perforin; smart00457
C2 domain of Perforin; cd04032
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that...; cd04273
ADAM-TS Spacer 1; pfam05986
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that...; cd04273
ADAM-TS Spacer 1; pfam05986
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
tyrosine decarboxylase MnfA; TIGR03812
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; cd06450
PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH  (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme.  DCoH stimulates gene expression by...; cd00914
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
ZU5 domain; pfam00791
Death domain found in Uncoordinated-5B; cd08802
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
ZU5 domain; pfam00791
Death domain found in Uncoordinated-5B; cd08802
Nucleoside transporter; cl15430
Nucleoside transporter; cl15430
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin repeat-like domain; cl15786
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Saposin/surfactant protein-B A-type DOMAIN; smart00162
Saposin-like type B, region 1; pfam05184
Saposin (B) Domains; smart00741
Saposin-like type B, region 2; pfam03489
Saposin (B) Domains; smart00741
Saposin-like type B, region 2; pfam03489
Saposin-like type B, region 1; pfam05184
Saposin (B) Domains; smart00741
Saposin-like type B, region 1; pfam05184
Saposin (B) Domains; smart00741
Saposin-like type B, region 2; pfam03489
Saposin A-type domain; pfam02199
Saposin/surfactant protein-B A-type DOMAIN; smart00162
Saposin-like type B, region 1; pfam05184
Saposin (B) Domains; smart00741
Saposin-like type B, region 2; pfam03489
Saposin (B) Domains; smart00741
Saposin-like type B, region 2; pfam03489
Saposin-like type B, region 1; pfam05184
Saposin (B) Domains; smart00741
Saposin-like type B, region 1; pfam05184
Saposin (B) Domains; smart00741
Saposin-like type B, region 2; pfam03489
Saposin A-type domain; pfam02199
Saposin/surfactant protein-B A-type DOMAIN; smart00162
Saposin-like type B, region 1; pfam05184
Saposin (B) Domains; smart00741
Saposin-like type B, region 2; pfam03489
Saposin (B) Domains; smart00741
Saposin-like type B, region 2; pfam03489
Saposin-like type B, region 1; pfam05184
Saposin (B) Domains; smart00741
Saposin-like type B, region 1; pfam05184
Saposin (B) Domains; smart00741
Saposin-like type B, region 2; pfam03489
Saposin A-type domain; pfam02199
Sulfotransferase domain; pfam00685
Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cd00104
SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate...; cd00252
Secreted protein acidic and rich in cysteine Ca binding region; pfam10591
Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases; cd00191
Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cd00104
SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate...; cd00252
Secreted protein acidic and rich in cysteine Ca binding region; pfam10591
Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases; cd00191
K homology RNA-binding domain_vigilin_like.  The vigilin family is a large and extended family of multiple KH-domain proteins, including vigilin, also called high density lipoprotein binding protien (HBP), fungal Scp160 and bicaudal-C. Yeast Scp160p has...; cd02394
unknown protein; Provisional
AKAP7 2'5' RNA ligase-like domain; pfam10469
K homology RNA-binding domain_vigilin_like.  The vigilin family is a large and extended family of multiple KH-domain proteins, including vigilin, also called high density lipoprotein binding protien (HBP), fungal Scp160 and bicaudal-C. Yeast Scp160p has...; cd02394
unknown protein; Provisional
AKAP7 2'5' RNA ligase-like domain; pfam10469
K homology RNA-binding domain_vigilin_like.  The vigilin family is a large and extended family of multiple KH-domain proteins, including vigilin, also called high density lipoprotein binding protien (HBP), fungal Scp160 and bicaudal-C. Yeast Scp160p has...; cd02394
unknown protein; Provisional
AKAP7 2'5' RNA ligase-like domain; pfam10469
RTP801 C-terminal region; pfam07809
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
Domain of unknown function (DUF1977); pfam09320
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
Domain of unknown function (DUF1977); pfam09320
EF hand; pfam13202
EF-hand domain pair; pfam13833
EF hand; pfam13202
EF-hand domain pair; pfam13833
EF hand; pfam13202
EF-hand domain pair; pfam13833
Protein of unknown function, DUF607; pfam04678
Protein of unknown function, DUF607; pfam04678
Protein of unknown function, DUF607; pfam04678
Calcium-binding EGF-like domain; smart00179
Zona pellucida-like domain; pfam00100
Group XII secretory phospholipase A2 precursor (PLA2G12); pfam06951
Prolyl 4-Hydroxylase alpha-subunit, N-terminal region; pfam08336
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam03171
Prolyl 4-Hydroxylase alpha-subunit, N-terminal region; pfam08336
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam03171
Prolyl 4-Hydroxylase alpha-subunit, N-terminal region; pfam08336
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam03171
Prolyl 4-Hydroxylase alpha-subunit, N-terminal region; pfam08336
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam03171
NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding [DNA replication, recombination, and repair]; COG2816
NADH pyrophosphatase-like rudimentary NUDIX domain; pfam09296
NADH pyrophosphatase zinc ribbon domain; pfam09297
NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; cd03429
SGT1 protein; pfam07093
SGT1 protein; pfam07093
SGT1 protein; pfam07093
Putative binding domain; pfam13900
Protein of unknown function (DUF3719); pfam12516
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]; COG0484
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
ribosomal protein S16; TIGR00002
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Zinc-finger of mitochondrial splicing suppressor 51; pfam13824
MYND finger; pfam01753
PP2B, metallophosphatase domain; cd07416
Protein phosphatase 2A homologues, catalytic domain; smart00156
PP2B, metallophosphatase domain; cd07416
Protein phosphatase 2A homologues, catalytic domain; smart00156
PP2B, metallophosphatase domain; cd07416
Protein phosphatase 2A homologues, catalytic domain; smart00156
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cd02257
Calcineurin-binding protein (Calsarcin); pfam05556
Calcineurin-binding protein (Calsarcin); pfam05556
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
Putative GTPase activating protein for Arf; pfam01412
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]
Sec23/Sec24 zinc finger; pfam04810
Sec24-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the budding and fusion of intracellular transport vesicles that selectively carry cargo proteins and lipids from donor to acceptor organelles. The two main classes...; cd01479
Sec23/Sec24 beta-sandwich domain; pfam08033
Sec23/Sec24 helical domain; pfam04815
Gelsolin repeat; pfam00626
Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]
Sec23/Sec24 zinc finger; pfam04810
Sec24-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the budding and fusion of intracellular transport vesicles that selectively carry cargo proteins and lipids from donor to acceptor organelles. The two main classes...; cd01479
Sec23/Sec24 beta-sandwich domain; pfam08033
Sec23/Sec24 helical domain; pfam04815
Gelsolin repeat; pfam00626
Glycosyltransferase family 10 (fucosyltransferase); pfam00852
CHCH domain; pfam06747
heparan sulfate-N-deacetylase; pfam12062
Sulfotransferase domain; pfam00685
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Calcium/calmodulin dependent protein kinase II Association; pfam08332
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Calcium/calmodulin dependent protein kinase II Association; pfam08332
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Calcium/calmodulin dependent protein kinase II Association; pfam08332
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Calcium/calmodulin dependent protein kinase II Association; pfam08332
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Calcium/calmodulin dependent protein kinase II Association; pfam08332
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Calcium/calmodulin dependent protein kinase II Association; pfam08332
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and...; cd00108
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and...; cd00108
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Vinculin family; pfam01044
Vinculin family; pfam01044
Vinculin family; pfam01044
Vinculin family; pfam01044
Clathrin adaptor complex small chain; cl02092
C-terminal domain of medium Mu3A subunit in ubiquitously expressed adaptor protein (AP) complex AP-3; cd09260
Adaptor complexes medium subunit family; pfam00928
Clathrin adaptor complex small chain; cl02092
C-terminal domain of medium Mu3A subunit in ubiquitously expressed adaptor protein (AP) complex AP-3; cd09260
Adaptor complexes medium subunit family; pfam00928
Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside analogues at the 5'-hydroxyl using ATP or GTP as the phosphate donor.The physiological function of AK is associated with the regulation of extracellular adenosine...; cd01168
adenosine kinase; Provisional
Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside analogues at the 5'-hydroxyl using ATP or GTP as the phosphate donor.The physiological function of AK is associated with the regulation of extracellular adenosine...; cd01168
adenosine kinase; Provisional
Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside analogues at the 5'-hydroxyl using ATP or GTP as the phosphate donor.The physiological function of AK is associated with the regulation of extracellular adenosine...; cd01168
adenosine kinase; Provisional
Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside analogues at the 5'-hydroxyl using ATP or GTP as the phosphate donor.The physiological function of AK is associated with the regulation of extracellular adenosine...; cd01168
adenosine kinase; Provisional
Domain in histone families 1 and 5; smart00526
PHD-finger; pfam00628
PHD-finger; pfam00628
BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in...; cl02608
probable histone acetyltransferase MYST; Provisional
MOZ/SAS family; pfam01853
Domain in histone families 1 and 5; smart00526
PHD-finger; pfam00628
PHD-finger; pfam00628
BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in...; cl02608
probable histone acetyltransferase MYST; Provisional
MOZ/SAS family; pfam01853
Domain in histone families 1 and 5; smart00526
PHD-finger; pfam00628
PHD-finger; pfam00628
BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in...; cl02608
probable histone acetyltransferase MYST; Provisional
MOZ/SAS family; pfam01853
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
SAM domain of sphingomyelin synthase related subfamily; cd09515
Sterile alpha motif; smart00454
PAP2 superfamily C-terminal; pfam14360
SAM domain of sphingomyelin synthase related subfamily; cd09515
Sterile alpha motif; smart00454
PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; cl00474
Voltage-dependent anion channel of the outer mitochondrial membrane; cd07306
Voltage-dependent anion channel of the outer mitochondrial membrane; cd07306
Voltage-dependent anion channel of the outer mitochondrial membrane; cd07306
O-methyltransferase; pfam01596
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
NocA-like zinc-finger protein 1; pfam12402
Leucine Rich repeats (2 copies); pfam12799
Ion transport protein; pfam00520
Ion channel; pfam07885
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Calcium-activated BK potassium channel alpha subunit; pfam03493
Ion transport protein; pfam00520
Ion channel; pfam07885
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Calcium-activated BK potassium channel alpha subunit; pfam03493
Ion transport protein; pfam00520
Ion channel; pfam07885
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Calcium-activated BK potassium channel alpha subunit; pfam03493
Ion transport protein; pfam00520
Ion channel; pfam07885
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Calcium-activated BK potassium channel alpha subunit; pfam03493
Ion transport protein; pfam00520
Ion channel; pfam07885
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Calcium-activated BK potassium channel alpha subunit; pfam03493
Ion transport protein; pfam00520
Ion channel; pfam07885
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Calcium-activated BK potassium channel alpha subunit; pfam03493
CcmE; cl00994
Takusan; pfam04822
Plant protein of unknown function (DUF827); pfam05701
flagellar biosynthesis chaperone; Validated; cl09161
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src homology 3 domain of Disks Large homolog 5; cd11860
Guanylate kinase homologues; smart00072
Guanylate kinase; pfam00625
DNA-directed RNA polymerase subunit A'; Validated
RNA polymerase Rpb1, domain 1; pfam04997
RNA polymerase I subunit A N-terminus; smart00663
RNA polymerase Rpb1, domain 3; pfam04983
RNA polymerase Rpb1, domain 4; pfam05000
RNA polymerase Rpb1, domain 5; pfam04998
Largest subunit (Rpc1) of Eukaryotic RNA polymerase III (RNAP III), C-terminal domain; cd02736
40S ribosomal protein S24; Provisional
40S ribosomal protein S24; Provisional
40S ribosomal protein S24; Provisional
40S ribosomal protein S24; Provisional
40S ribosomal protein S24; Provisional
40S ribosomal protein S24; Provisional
MIZ/SP-RING zinc finger; pfam02891
cyclophilin_ABH_like: Cyclophilin  A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which...; cd01926
Zinc knuckle; pfam13696
Zinc-binding domain; pfam13695
eukaryotic translation initiation factor 5A; Provisional
S1_eIF5A: Eukaryotic translation Initiation Factor 5A (eIF5A), S1-like RNA-binding domain. eIF5A is an evolutionarily conserved protein found in eukaryotes. eIF5A is the only protein known to have the unusual amino acid hypusine. Hypusine is essential...; cd04468
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
Collagen triple helix repeat (20 copies); pfam01391
Lung surfactant protein D coiled-coil trimerisation; pfam09006
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
S-adenosylmethionine synthetase, N-terminal domain; pfam00438
S-adenosylmethionine synthetase; TIGR01034
S-adenosylmethionine synthetase, central domain; pfam02772
S-adenosylmethionine synthetase, C-terminal domain; pfam02773
Dpy-30 motif; pfam05186
Dpy-30 motif; pfam05186
Dpy-30 motif; pfam05186
Dpy-30 motif; pfam05186
Dpy-30 motif; pfam05186
Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these...; cd02970
AhpC/TSA antioxidant enzyme; pfam13911
Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these...; cd02970
AhpC/TSA antioxidant enzyme; pfam13911
Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these...; cd02970
AhpC/TSA antioxidant enzyme; pfam13911
Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these...; cd02970
AhpC/TSA antioxidant enzyme; pfam13911
Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these...; cd02970
AhpC/TSA antioxidant enzyme; pfam13911
Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these...; cd02970
AhpC/TSA antioxidant enzyme; pfam13911
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), TM4SF9_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment...; cd03159
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), TM4SF9_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment...; cd03159
Neuregulin family; pfam02158
Neuregulin family; pfam02158
EGF-like protein; Provisional
Bax inhibitor 1 like; pfam12811
Growth-hormone inducible transmembrane protein; cd10431
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Immunoglobulin like; smart00410
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the delta1 receptor of an orphan glutamate receptor family; cd06392
Receptor family ligand binding region; pfam01094
Bacterial extracellular solute-binding proteins, family 3; pfam00497
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Ligand-gated ion channel; pfam00060
Eukaryotic homologues of bacterial periplasmic substrate binding proteins; smart00079
Wings apart-like protein regulation of heterochromatin; pfam07814
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
ZASP-like motif; smart00735
ZASP-like motif; smart00735
The first LIM domain of ZASP/Cypher family; cd09454
The second LIM domain of Enigma-like family; cd09362
The third LIM domain of ZASP/Cypher family; cd09460
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
ZASP-like motif; smart00735
The first LIM domain of ZASP/Cypher family; cd09454
The second LIM domain of Enigma-like family; cd09362
The third LIM domain of ZASP/Cypher family; cd09460
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
ZASP-like motif; smart00735
The first LIM domain of ZASP/Cypher family; cd09454
The second LIM domain of Enigma-like family; cd09362
The third LIM domain of ZASP/Cypher family; cd09460
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
ZASP-like motif; smart00735
ZASP-like motif; smart00735
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
ZASP-like motif; smart00735
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
ZASP-like motif; smart00735
Activin types I and II receptor domain; pfam01064
Transforming growth factor beta type I GS-motif; cl02621
Protein kinase domain; pfam00069
Catalytic domain of Protein Kinases; cd00180
EMI domain; pfam07546
C1q domain; pfam00386
Synuclein; pfam01387
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
Putative GTPase activating protein for Arf; pfam01412
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; COG0334
Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; pfam02812
NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; cd01076
NUT protein N terminus; pfam12881
NUT protein C terminal; pfam12882
NUT protein C terminal; pfam12882
NUT protein N terminus; pfam12881
NUT protein C terminal; pfam12882
Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; cd07061
Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; cd07061
Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; cd07061
Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; cd07061
Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically 'activated' sulfate form important for the assimilation of...; cd02027
ATP sulphurylase; TIGR00339
ATP-sulfurylase; cd00517
Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically 'activated' sulfate form important for the assimilation of...; cd02027
ATP sulphurylase; TIGR00339
ATP-sulfurylase; cd00517
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cl00053
C2 domain of PTEN tumour-suppressor protein; pfam10409
Predicted NAD/FAD-dependent oxidoreductase [General function prediction only]
NAD(P)-binding Rossmann-like domain; pfam13450
Predicted NAD/FAD-dependent oxidoreductase [General function prediction only]
NAD(P)-binding Rossmann-like domain; pfam13450
Partial alpha/beta-hydrolase lipase region; pfam04083
alpha/beta hydrolase fold; pfam00561
triacylglycerol lipase
Partial alpha/beta-hydrolase lipase region; pfam04083
triacylglycerol lipase
Partial alpha/beta-hydrolase lipase region; pfam04083
triacylglycerol lipase
Partial alpha/beta-hydrolase lipase region; pfam04083
triacylglycerol lipase
Partial alpha/beta-hydrolase lipase region; pfam04083
Partial alpha/beta-hydrolase lipase region; pfam04083
alpha/beta hydrolase fold; pfam00561
Partial alpha/beta-hydrolase lipase region; pfam04083
alpha/beta hydrolase fold; pfam00561
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Partial alpha/beta-hydrolase lipase region; pfam04083
alpha/beta hydrolase fold; pfam00561
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Mov34/MPN/PAD-1 family; cd08066
Actin; pfam00022
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Actin; pfam00022
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Death domain of FAS or TNF receptor superfamily member 6; cd08316
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Death domain of FAS or TNF receptor superfamily member 6; cd08316
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Sterol desaturase [Lipid metabolism]; COG3000
Fatty acid hydroxylase superfamily; pfam04116
Partial alpha/beta-hydrolase lipase region; pfam04083
alpha/beta hydrolase fold; pfam00561
Partial alpha/beta-hydrolase lipase region; pfam04083
alpha/beta hydrolase fold; pfam00561
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
TPR repeat; pfam13414
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13432
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13432
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
TPR repeat; pfam13414
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam00515
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam00515
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam00515
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam00515
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam00515
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
monocarboxylate transporter 1; TIGR00892
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Fumble; pfam03630
pantothenate kinase, eukaryotic/staphyloccocal type; TIGR00555
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cl17037
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cl17037
Fumble; pfam03630
pantothenate kinase, eukaryotic/staphyloccocal type; TIGR00555
Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; cl00286
Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; cl00286
Kinesin motor domain, KIF23-like subgroup. Members of this group may play a role in mitosis. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Kinesins are microtubule-dependent molecular motors that play...; cd01368
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
RNase P subunit p30; pfam01876
Putative binding domain; pfam13900
RNase P subunit p30; pfam01876
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
Putative phosphatase regulatory subunit; pfam03370
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
SAM domain of tankyrase1,2 subfamily; cd09524
SAM domain (Sterile alpha motif); pfam07647
Tankyrases interact with the telomere reverse transcriptase complex (TERT). Tankyrase 1 poly-ADP-ribosylates Telomere Repeat Binding Factor 1 (TRF1) while Tankyrase 2 can poly-ADP-ribosylate itself or TRF1. The tankyrases also contain multiple ankyrin...; cd01438
FGF binding protein 1 (FGF-BP1); pfam06473
Domain of unknown function (DUF3535); pfam12054
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins; smart00744
Secreted/periplasmic Zn-dependent peptidases, insulinase-like [Posttranslational modification, protein turnover, chaperones]; COG1025
Insulinase (Peptidase family M16); pfam00675
Peptidase M16 inactive domain; pfam05193
Peptidase M16 inactive domain; pfam05193
Peptidase M16 inactive domain; pfam05193
Kinesin motor domain, BimC/Eg5 spindle pole proteins, participate in spindle assembly and chromosome segregation during cell division. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Kinesins are...; cd01364
Kinesin motor, catalytic domain. ATPase; smart00129
Kinesin-associated microtubule-binding; pfam13931
Homeobox domain; pfam00046
Exocyst complex subunit Sec15-like; pfam04091
Exocyst complex subunit Sec15-like; pfam04091
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
3-epi-6-deoxocathasterone 23-monooxygenase; Provisional
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
C2 domain first repeat in Ferlin; cd08373
C2 domain second repeat in Ferlin; cd04011
FerI (NUC094) domain; pfam08151
C2 domain third repeat in Ferlin; cd04018
FerA (NUC095) domain; pfam08165
FerB (NUC096) domain; pfam08150
Dysferlin domain, N-terminal region; smart00693
Dysferlin domain, N-terminal region; smart00693
C2 domain fourth repeat in Ferlin; cd04017
C2 domain; cl14603
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
C2 domain first repeat in Ferlin; cd08373
C2 domain second repeat in Ferlin; cd04011
FerI (NUC094) domain; pfam08151
C2 domain third repeat in Ferlin; cd04018
FerA (NUC095) domain; pfam08165
FerB (NUC096) domain; pfam08150
Dysferlin domain, N-terminal region; smart00693
Dysferlin domain, N-terminal region; smart00693
C2 domain fourth repeat in Ferlin; cd04017
C2 domain; cl14603
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
TSG101 and ALIX binding domain of CEP55; pfam12180
TSG101 and ALIX binding domain of CEP55; pfam12180
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Domain present in phytochromes and cGMP-specific phosphodiesterases; smart00065
FOG: GAF domain [Signal transduction mechanisms]; COG2203
Domain present in phytochromes and cGMP-specific phosphodiesterases; smart00065
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Folate-sensitive fragile site protein Fra10Ac1; pfam09725
Leucine rich repeat; pfam13855
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine rich repeat C-terminal domain; smart00082
EPTP domain; pfam03736
EPTP domain; pfam03736
EPTP domain; pfam03736
EPTP domain; pfam03736
EPTP domain; pfam03736
EPTP domain; pfam03736
EPTP domain; pfam03736
Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; COG0697
EamA-like transporter family; pfam00892
Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; COG0697
EamA-like transporter family; pfam00892
RasGEF domain; pfam00617
Phosphoinositide-specific phospholipase C, efhand-like; pfam09279
Catalytic domain of metazoan phosphoinositide-specific phospholipase C-epsilon; cd08596
Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; cl14615
Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; cl14615
C2 domain present in Phosphoinositide-specific phospholipases C (PLC); cd00275
Ubiquitin-like domain of Phosphatidylinositide-specific phospholipase; cd01780
RasGEF domain; pfam00617
Phosphoinositide-specific phospholipase C, efhand-like; pfam09279
Catalytic domain of metazoan phosphoinositide-specific phospholipase C-epsilon; cd08596
Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; cl14615
Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; cl14615
C2 domain present in Phosphoinositide-specific phospholipases C (PLC); cd00275
Ubiquitin-like domain of Phosphatidylinositide-specific phospholipase; cd01780
Protein involved in the nuclear export of pre-ribosomes [Translation, ribosomal structure and biogenesis / Intracellular trafficking and secretion]; COG5117
Nucleolar complex-associated protein; pfam07540
CBF/Mak21 family; pfam03914
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; COG0365
AMP-binding enzyme; pfam00501
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
ZASP-like motif; smart00735
This family represents the LIM domain of CLP36; cd09448
Sorbin homologous domain; pfam02208
First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11919
Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11922
Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11916
Sorbin homologous domain; pfam02208
First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11919
Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11922
Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11916
Sorbin homologous domain; pfam02208
First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11919
Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11922
Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11916
Sorbin homologous domain; pfam02208
First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11919
Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11922
Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11916
Sorbin homologous domain; pfam02208
First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11919
Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11922
Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11916
Sorbin homologous domain; pfam02208
First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11919
Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11922
Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11916
Sorbin homologous domain; pfam02208
First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11919
Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11922
Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin; cd11916
AAK_P5CS_ProBA: Glutamate-5-kinase (G5K) domain of the bifunctional delta 1-pyrroline-5-carboxylate synthetase (P5CS), composed of an N-terminal G5K (ProB) and a C-terminal glutamyl 5- phosphate reductase (G5PR, ProA), the first and second enzyme...; cd04256
delta l-pyrroline-5-carboxylate synthetase; TIGR01092
Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; cd07079
AAK_P5CS_ProBA: Glutamate-5-kinase (G5K) domain of the bifunctional delta 1-pyrroline-5-carboxylate synthetase (P5CS), composed of an N-terminal G5K (ProB) and a C-terminal glutamyl 5- phosphate reductase (G5PR, ProA), the first and second enzyme...; cd04256
delta l-pyrroline-5-carboxylate synthetase; TIGR01092
Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; cd07079
Protein of unknown function (DUF1619); pfam07773
Protein of unknown function (DUF1619); pfam07773
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
GDA1/CD39 (nucleoside phosphatase) family; pfam01150
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cl17037
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cl17037
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cl00050
Cyclin, C-terminal domain; pfam02984
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cl00050
Cyclin, C-terminal domain; pfam02984
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cl00050
Cyclin, C-terminal domain; pfam02984
hypothetical protein
Src homology 2 (SH2) domain; cl15255
Src homology 2 (SH2) domain; cl15255
Src homology 2 (SH2) domain found in B-cell linker (BLNK) protein and SH2 domain-containing leukocyte protein of 76 kDa (SLP-76); cd09929
Src homology 2 (SH2) domain; cl15255
Src homology 2 (SH2) domain found in B-cell linker (BLNK) protein and SH2 domain-containing leukocyte protein of 76 kDa (SLP-76); cd09929
Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; cd00027
DNA polymerase X family; smart00483
Nucleotidyltransferase (NT) domain of family X DNA Polymerases; cd00141
Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; cd00027
DNA polymerase X family; smart00483
Nucleotidyltransferase (NT) domain of family X DNA Polymerases; cd00141
Zinc-dependent metalloprotease; BMP1/TLD-like subfamily. BMP1 (Bone morphogenetic protein 1) and TLD (tolloid)-like metalloproteases play vital roles in extracellular matrix formation, by cleaving precursor proteins such as enzymes, structural proteins; cd04281
Astacin (Peptidase family M12A); pfam01400
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Calcium-binding EGF-like domain; smart00179
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Endomembrane protein 70; pfam02990
helix-turn-helix, Psq domain; pfam05225
helix-turn-helix, Psq domain; pfam05225
helix-turn-helix, Psq domain; pfam05225
transcriptional regulator ICP4; Provisional
Leucine rich repeat N-terminal domain; smart00013
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat N-terminal domain; smart00013
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat N-terminal domain; smart00013
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat N-terminal domain; smart00013
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
RhoGAP_ARHGAP19: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP19-like proteins. The function of ArhGAP19 is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their...; cd04392
GTPase-activator protein for Rho-like GTPases; smart00324
RhoGAP_ARHGAP19: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP19-like proteins. The function of ArhGAP19 is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their...; cd04392
GTPase-activator protein for Rho-like GTPases; smart00324
RhoGAP_ARHGAP19: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP19-like proteins. The function of ArhGAP19 is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their...; cd04392
GTPase-activator protein for Rho-like GTPases; smart00324
Glycogen synthase kinase-3 binding; pfam05350
Glycogen synthase kinase-3 binding; pfam05350
NUC173 domain; pfam08161
NUC173 domain; pfam08161
Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; cd07067
Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; cd07067
Exosome complex exonuclease RRP4 N-terminal region; pfam14382
Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain) [Translation, ribosomal structure and biogenesis]
S1_CSL4: CSL4, S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. ScCSL4 protein is a subunit of the exosome complex. The exosome plays a central role in 3' to 5' RNA processing and degradation...; cd05791
DHHC palmitoyltransferase; pfam01529
DHHC palmitoyltransferase; pfam01529
DHHC palmitoyltransferase; pfam01529
DHHC palmitoyltransferase; pfam01529
DHHC palmitoyltransferase; pfam01529
NER and RNAPII transcription protein n terminal; pfam12460
HEAT-like repeat; pfam13513
dendritic cell derived ubiquitin-like protein; cd01794
Ubiquitin family; pfam00240
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; COG0329
Dihydrodipicolinate synthase family; cd00408
TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; cl09108
Dihydrodipicolinate synthase family; cd00408
MORN repeat; cl14787
MORN repeat; cl14787
MORN repeat; cl14787
MORN repeat; cl14787
MORN repeat; cl14787
MORN repeat; cl14787
Phosphatidylinositol 3- and 4-kinase; pfam00454
Membrane-associating domain; pfam01284
Protein present in Fab1, YOTB, Vac1, and EEA1; smart00064
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Protein present in Fab1, YOTB, Vac1, and EEA1; smart00064
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Protein present in Fab1, YOTB, Vac1, and EEA1; smart00064
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Protein present in Fab1, YOTB, Vac1, and EEA1; smart00064
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Protein present in Fab1, YOTB, Vac1, and EEA1; smart00064
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Protein present in Fab1, YOTB, Vac1, and EEA1; smart00064
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Protein present in Fab1, YOTB, Vac1, and EEA1; smart00064
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Cysteine-rich domain of the secreted frizzled-related protein 5 (SFRP5), a regulator of Wnt activity; cd07444
NTR domain, Secreted frizzled-related protein (Sfrp) 1-like subfamily; composed of proteins similar to human Sfrp1, Sfrp2 and Sfrp5. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse...; cd03580
Golgin subfamily A member 7/ERF4 family; pfam10256
Family description; pfam13517
Family description; pfam13517
FG-GAP repeat; pfam01839
Family description; pfam13517
ASPIC and UnbV; pfam07593
Calcium-binding EGF domain; pfam07645
Family description; pfam13517
Family description; pfam13517
FG-GAP repeat; pfam01839
Family description; pfam13517
ASPIC and UnbV; pfam07593
Calcium-binding EGF domain; pfam07645
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Lysyl oxidase; pfam01186
Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]
NAD(P)-binding Rossmann-like domain; pfam13450
Glycosyl hydrolase family 79, N-terminal domain; pfam03662
Glycosyl hydrolase family 79, N-terminal domain; pfam03662
Glycosyl hydrolase family 79, N-terminal domain; pfam03662
Glycosyl hydrolase family 79, N-terminal domain; pfam03662
Domain of unknown function DUF21; pfam01595
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; cd04590
aromatic amino acid aminotransferase; Provisional
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; cd00609
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Mitochondrial carrier protein; pfam00153
mitochondrial carrier protein; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Cytochrome oxidase assembly protein; cl15852
Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; COG1612
Cytochrome oxidase assembly protein; cl15852
Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; COG1612
Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; COG3142
multi drug resistance-associated protein (MRP); TIGR00957
ABC transporter transmembrane region; pfam00664
Domain 1 of the ABC subfamily C.  This family is also known as MRP (mulrtidrug resisitance-associated protein).  Some of the MRP members have five additional transmembrane segments in their N-terminas, but the function of these additional...; cd03250
ABC transporter transmembrane region; pfam00664
Domain 2 of the ABC subfamily C.  This family is also known as MRP (mulrtidrug resisitance-associated protein).  Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional...; cd03244
First N-terminal Src homology 3 domain of Dynamin Binding Protein, also called Tuba; cd11794
Second N-terminal Src homology 3 domain of Dynamin Binding Protein, also called Tuba; cd11795
Third N-terminal Src homology 3 domain of Dynamin Binding Protein, also called Tuba; cd11796
Fourth N-terminal Src homology 3 domain of Dynamin Binding Protein, also called Tuba; cd11797
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
BAR domain; smart00721
The Bin/Amphiphysin/Rvs (BAR) domain of Dynamin Binding Protein; cd07589
First C-terminal Src homology 3 domain of Dynamin Binding Protein, also called Tuba; cd11798
Second C-terminal Src homology 3 domain of Dynamin Binding Protein, also called Tuba, and similar domains; cd12141
Peptidase M14 carboxypeptidase subfamily N/E-like; Carboxypeptidase N subgroup; cd03864
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; cd11308
The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; cl02525
Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; COG0330
The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; cl02525
Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; COG0330
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Protein Kinases, catalytic domain; cl09925
I-kappa-kinase-beta NEMO binding domain; pfam12179
Schizosaccharomyces pombe CWF19 and related proteins, N-terminal metallophosphatase domain; cd07380
HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; cl00228
Protein similar to CwfJ C-terminus 2; pfam04676
Biogenesis of lysosome-related organelles complex-1 subunit 2; pfam10046
Polycystin cation channel; pfam08016
Polycystin cation channel; pfam08016
The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; cd03505
Fatty acid desaturase; pfam00487
The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; cd03505
found in Wnt-1; smart00097
wnt family; pfam00110
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16; cl14807
NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8); pfam05821
Cupin-like domain; pfam13621
Paired Box domain; cd00131
Paired Box domain; smart00351
Paired-box protein 2 C terminal; pfam12403
Paired Box domain; cd00131
Paired Box domain; smart00351
Paired-box protein 2 C terminal; pfam12403
Paired Box domain; cd00131
Paired Box domain; smart00351
Paired-box protein 2 C terminal; pfam12403
Paired Box domain; cd00131
Paired Box domain; smart00351
Paired-box protein 2 C terminal; pfam12403
Paired Box domain; cd00131
Paired Box domain; smart00351
Paired-box protein 2 C terminal; pfam12403
The Sema domain, a protein interacting module, of semaphorins and plexins; cl15693
semaphorin domain; smart00630
Plexin repeat; cl02601
The Sema domain, a protein interacting module, of semaphorins and plexins; cl15693
semaphorin domain; smart00630
Plexin repeat; pfam01437
Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4B; cd05872
Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain; smart00916
Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain; smart00916
Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain; smart00916
Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain; smart00916
GP4d_helicase is a homohexameric 5'-3' helicases. Helicases couple NTP hydrolysis to the unwinding of nucleic acid duplexes into their component strands; cd01122
AAA domain; pfam13481
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
AAA domain; pfam13481
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
AAA domain; pfam13481
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
AAA domain; pfam13481
Fez1; pfam06818
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Domains similar to the N-terminal protein-binding module of harmonin; cd07358
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Tricarboxylate carrier; pfam03820
Insulin growth factor-binding protein homologues; smart00121
Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cd00104
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
D domain of beta-TrCP; smart01028
F-box-like; pfam12937
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
D domain of beta-TrCP; smart01028
F-box-like; pfam12937
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
D domain of beta-TrCP; smart01028
F-box-like; pfam12937
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
DNA polymerase X family; smart00483
Nucleotidyltransferase (NT) domain of family X DNA Polymerases; cd00141
DNA polymerase X family; smart00483
Nucleotidyltransferase (NT) domain of family X DNA Polymerases; cd00141
DNA polymerase X family; smart00483
Nucleotidyltransferase (NT) domain of family X DNA Polymerases; cd00141
F-box-like; pfam12937
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
Nucleoplasmin; pfam03066
beta-N-acetylglucosaminidase; pfam07555
beta-N-acetylglucosaminidase; pfam07555
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13833
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Domain of unknown function (DUF1741); pfam08427
LIM-domain binding protein; pfam01803
LIM-domain binding protein; pfam01803
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
SRP40, C-terminal domain; pfam05022
GNS1/SUR4 family; pfam01151
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
OAR domain; pfam03826
Guanine nucleotide exchange factor in Golgi transport N-terminal; pfam12783
Sec7 domain; pfam01369
Guanine nucleotide exchange factor in Golgi transport N-terminal; pfam12783
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor...; cd00171
Guanine nucleotide exchange factor in Golgi transport N-terminal; pfam12783
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor...; cd00171
N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor kappa B2 (NF-kappa B2); cd07934
IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to...; cd01177
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Death domain of the Nuclear Factor-KappaB2 precursor protein p100; cd08798
N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor kappa B2 (NF-kappa B2); cd07934
IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to...; cd01177
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Death domain of the Nuclear Factor-KappaB2 precursor protein p100; cd08798
N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor kappa B2 (NF-kappa B2); cd07934
IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to...; cd01177
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Death domain of the Nuclear Factor-KappaB2 precursor protein p100; cd08798
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor...; cd00171
EFA6 Pleckstrin Homology (PH) domain; cd01230
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor...; cd00171
EFA6 Pleckstrin Homology (PH) domain; cd01230
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor...; cd00171
EFA6 Pleckstrin Homology (PH) domain; cd01230
Antagonist of mitotic exit network protein 1; cl15308
CUE domain; cl02655
Actin; smart00268
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Suppressor of fused protein (SUFU); pfam05076
Suppressor of Fused Gli/Ci N terminal binding domain; pfam12470
Suppressor of fused protein (SUFU); pfam05076
Suppressor of Fused Gli/Ci N terminal binding domain; pfam12470
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
Inhibitor of growth proteins N-terminal histone-binding; pfam12998
Arf-like 3 (Arl3) GTPase; cd04155
GTPase SAR1 and related small G proteins [General function prediction only]
Tricarboxylate carrier; pfam03820
WW domain-binding protein 1; pfam11669
WW domain-binding protein 1; pfam11669
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Methyltransferase domain; pfam13847
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Domain of unknown function DUF21; pfam01595
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; cd04590
Domain of unknown function DUF21; pfam01595
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; cd04590
Domain of unknown function DUF21; pfam01595
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; cd04590
5' nucleotidase family; pfam05761
HAD superfamily (subfamily IG) hydrolase, 5'-nucleotidase; TIGR02244
5' nucleotidase family; pfam05761
HAD superfamily (subfamily IG) hydrolase, 5'-nucleotidase; TIGR02244
Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; COG0036
Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; cd00429
Intermediate filament head (DNA binding) region; pfam04732
Intermediate filament protein; pfam00038
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
TAF5_NTD2 is the second conserved N-terminal region of TATA Binding Protein (TBP) Associated Factor 5 (TAF5), involved in forming Transcription Factor IID (TFIID); cd08044
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
S1_Rrp5_repeat_hs1_sc1: Rrp5 is a trans-acting factor important for biogenesis of both the 40S and 60S eukaryotic ribosomal subunits. Rrp5 has two distinct regions, an N-terminal region containing tandemly repeated S1 RNA-binding domains (12 S1 repeats...; cd05693
S1_Rrp5_repeat_hs2_sc2: Rrp5 is a trans-acting factor important for biogenesis of both the 40S and 60S eukaryotic ribosomal subunits. Rrp5 has two distinct regions, an N-terminal region containing tandemly repeated S1 RNA-binding domains (12 S1 repeats...; cd05694
Ribosomal protein S1 [Translation, ribosomal structure and biogenesis]; COG0539
S1_Rrp5_repeat_hs3: Rrp5 is a trans-acting factor important for biogenesis of both the 40S and 60S eukaryotic ribosomal subunits. Rrp5 has two distinct regions, an N-terminal region containing tandemly repeated S1 RNA-binding domains (12 S1 repeats in...; cd05695
S1_Rrp5_repeat_hs4: Rrp5 is a trans-acting factor important for biogenesis of both the 40S and 60S eukaryotic ribosomal subunits. Rrp5 has two distinct regions, an N-terminal region containing tandemly repeated S1 RNA-binding domains (12 S1 repeats in...; cd05696
S1_Rrp5_repeat_hs5: Rrp5 is a trans-acting factor important for biogenesis of both the 40S and 60S eukaryotic ribosomal subunits. Rrp5 has two distinct regions, an N-terminal region containing tandemly repeated S1 RNA-binding domains (12 S1 repeats in...; cd05697
S1_Rrp5_repeat_hs6_sc5: Rrp5 is a trans-acting factor important for biogenesis of both the 40S and 60S eukaryotic ribosomal subunits. Rrp5 has two distinct regions, an N-terminal region containing tandemly repeated S1 RNA-binding domains (12 S1 repeats...; cd05698
Ribosomal protein S1 [Translation, ribosomal structure and biogenesis]; COG0539
S1_Rrp5_repeat_hs7: Rrp5 is a trans-acting factor important for biogenesis of both the 40S and 60S eukaryotic ribosomal subunits. Rrp5 has two distinct regions, an N-terminal region containing tandemly repeated S1 RNA-binding domains (12 S1 repeats in...; cd05699
S1_Rrp5_repeat_hs8_sc7: Rrp5 Homo sapiens S1 repeat 8 (hs8) and Saccharomyces cerevisiae S1 repeat 7 (sc7)-like domains. Rrp5 is a trans-acting factor important for biogenesis of both the 40S and 60S eukaryotic ribosomal subunits.  Rrp5 has two distinct...; cd04461
S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; cl09927
S1_Rrp5_repeat_hs10: Rrp5 is a trans-acting factor important for biogenesis of both the 40S and 60S eukaryotic ribosomal subunits. Rrp5 has two distinct regions, an N-terminal region containing tandemly repeated S1 RNA-binding domains (12 S1 repeats in...; cd05701
S1_Rrp5_repeat_hs11_sc8: Rrp5 is a trans-acting factor important for biogenesis of both the 40S and 60S eukaryotic ribosomal subunits. Rrp5 has two distinct regions, an N-terminal region containing tandemly repeated S1 RNA-binding domains (12 S1 repeats...; cd05702
S1_Rrp5_repeat_hs12_sc9: Rrp5 is a trans-acting factor important for biogenesis of both the 40S and 60S eukaryotic ribosomal subunits. Rrp5 has two distinct regions, an N-terminal region containing tandemly repeated S1 RNA-binding domains (12 S1 repeats...; cd05703
S1_Rrp5_repeat_hs13: Rrp5 is a trans-acting factor important for biogenesis of both the 40S and 60S eukaryotic ribosomal subunits.  Rrp5 has two distinct regions, an N-terminal region containing tandemly repeated S1 RNA-binding domains (12 S1 repeats in...; cd05704
S1_Rrp5_repeat_hs14: Rrp5 is a trans-acting factor important for biogenesis of both the 40S and 60S eukaryotic ribosomal subunits. Rrp5 has two distinct regions, an N-terminal region containing tandemly repeated S1 RNA-binding domains (12 S1 repeats in...; cd05705
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
domain in neuralized proteins; smart00588
domain in neuralized proteins; smart00588
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
The phosphoinositide binding Phox Homology domain of Five SH protein; cd06888
First Src homology 3 domain of Tyrosine kinase substrate (Tks) proteins; cd12015
Second Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains; cd12077
Third Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains; cd12079
Fourth Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains; cd12019
Fifth (C-terminal) Src homology 3 domain of Tyrosine kinase substrate with five SH3 domains; cd12020
hOBFC1_like: A subfamily of OB folds similar to that found in human OB fold containing protein 1 (hOBFC1). Members of this group belong to the Replication protein A subunit 2 (RPA2) family of OB folds. RPA is a nuclear ssDNA binding protein (SSB) which...; cd04483
Domain of unknown function (DUF1879); pfam09170
Catalytic domain of the Protein Serine/Threonine Kinase, Ste20-like kinase; cd06643
Serine/Threonine protein kinases, catalytic domain; smart00220
Polo kinase kinase; pfam12474
Double-strand recombination repair protein; pfam10376
Double-strand recombination repair protein; pfam10376
FOG: WD40 repeat [General function prediction only]
F0F1-type ATP synthase, subunit b [Energy production and conversion]; COG0711
GST_N family, Class Omega subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; cd03055
Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; COG0625
C-terminal, alpha helical domain of Class Omega Glutathione S-transferases; cd03184
GST_N family, Class Omega subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; cd03055
Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; COG0625
C-terminal, alpha helical domain of Class Omega Glutathione S-transferases; cd03184
Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; cl00388
Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; COG0625
C-terminal, alpha helical domain of Class Omega Glutathione S-transferases; cd03184
GST_N family, Class Omega subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; cd03055
Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; COG0625
C-terminal, alpha helical domain of Class Omega Glutathione S-transferases; cd03184
GST_N family, Class Omega subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; cd03055
Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; COG0625
C-terminal, alpha helical domain of the Glutathione S-transferase family; cl02776
Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; cl00388
Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; COG0625
C-terminal, alpha helical domain of Class Omega Glutathione S-transferases; cd03184
Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; cl00388
Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; COG0625
C-terminal, alpha helical domain of the Glutathione S-transferase family; cl02776
Mab-21 protein; pfam03281
chromosome segregation protein SMC, common bacterial type; TIGR02168
VPS10 domain; smart00602
PKD domain; pfam00801
VPS10 domain; smart00602
PKD domain; pfam00801
VPS10 domain; smart00602
PKD domain; pfam00801
VPS10 domain; smart00602
PKD domain; pfam00801
VPS10 domain; smart00602
PKD domain; pfam00801
VPS10 domain; smart00602
PKD domain; pfam00801
VPS10 domain; smart00602
PKD domain; pfam00801
Creatinase/Prolidase N-terminal domain; pfam01321
Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; COG0006
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; cd01085
Creatinase/Prolidase N-terminal domain; pfam01321
Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; COG0006
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; cd01085
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); cl00214
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); cl00214
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); cl00214
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by...; cd01446
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
Eukaryotic SMC3 proteins; SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains.  Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal...; cd03272
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; cl12013
SMC proteins Flexible Hinge Domain; smart00968
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
U1-like zinc finger; smart00451
Domain in DAP-5, eIF4G, MA-3 and other proteins; smart00544
Domain in DAP-5, eIF4G, MA-3 and other proteins; smart00544
Domain in DAP-5, eIF4G, MA-3 and other proteins; smart00544
Domain in DAP-5, eIF4G, MA-3 and other proteins; smart00544
Domain in DAP-5, eIF4G, MA-3 and other proteins; smart00544
Domain in DAP-5, eIF4G, MA-3 and other proteins; smart00544
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Glycerol-3-phosphate O-acyltransferase [Lipid metabolism]; COG2937
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; cd07993
Glycerol-3-phosphate O-acyltransferase [Lipid metabolism]; COG2937
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; cd07993
Zona pellucida (ZP) domain; smart00241
long-chain acyl-CoA synthetase
AMP-binding enzyme; pfam00501
long-chain acyl-CoA synthetase
AMP-binding enzyme; pfam00501
long-chain acyl-CoA synthetase
AMP-binding enzyme; pfam00501
DHHC palmitoyltransferase; pfam01529
Vesicle transport v-SNARE protein N-terminus; pfam05008
Snare region anchored in the vesicle membrane C-terminus; pfam12352
N-terminal CTNNB1 binding; pfam08347
N-terminal CTNNB1 binding; pfam08347
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
N-terminal CTNNB1 binding; pfam08347
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
N-terminal CTNNB1 binding; pfam08347
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
N-terminal CTNNB1 binding; pfam08347
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
N-terminal CTNNB1 binding; pfam08347
N-terminal CTNNB1 binding; pfam08347
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
N-terminal CTNNB1 binding; pfam08347
N-terminal CTNNB1 binding; pfam08347
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
N-terminal CTNNB1 binding; pfam08347
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
N-terminal CTNNB1 binding; pfam08347
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
N-terminal CTNNB1 binding; pfam08347
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
N-terminal CTNNB1 binding; pfam08347
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
N-terminal CTNNB1 binding; pfam08347
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
N-terminal CTNNB1 binding; pfam08347
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
N-terminal CTNNB1 binding; pfam08347
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and...; cd00108
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and...; cd00108
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
The LIM domain of N-RAP; cd09446
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; pfam00880
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; pfam00880
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; cl11595
The Nebulin repeat is present also in Las1; smart00227
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; cl11595
The Nebulin repeat is present also in Las1; smart00227
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; pfam00880
Nebulin repeat; cl11595
Nebulin repeat; cl11595
Nebulin repeat; cl11595
Nebulin repeat; cl11595
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; cl11595
Nebulin repeat; cl11595
The LIM domain of N-RAP; cd09446
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; pfam00880
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; pfam00880
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; cl11595
The Nebulin repeat is present also in Las1; smart00227
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; cl11595
The Nebulin repeat is present also in Las1; smart00227
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; pfam00880
Nebulin repeat; cl11595
Nebulin repeat; cl11595
Nebulin repeat; cl11595
Nebulin repeat; cl11595
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; cl11595
Nebulin repeat; cl11595
The LIM domain of N-RAP; cd09446
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; pfam00880
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; pfam00880
The Nebulin repeat is present also in Las1; smart00227
The Nebulin repeat is present also in Las1; smart00227
The Nebulin repeat is present also in Las1; smart00227
The Nebulin repeat is present also in Las1; smart00227
The Nebulin repeat is present also in Las1; smart00227
Nebulin repeat; pfam00880
Nebulin repeat; cl11595
The Nebulin repeat is present also in Las1; smart00227
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cl00042
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
Metallo-beta-lactamase superfamily; smart00849
DNA repair metallo-beta-lactamase; pfam07522
haloacid dehalogenase-like hydrolase family protein
TlpA-like family, DipZ-like subfamily; composed uncharacterized proteins containing a TlpA-like TRX domain. Some members show domain architectures similar to that of E. coli DipZ protein (also known as DsbD). The only eukaryotic members of the TlpA...; cd03012
NHL repeat; pfam01436
NHL repeat; pfam01436
NHL repeat; pfam01436
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
chromosome segregation protein SMC, common bacterial type; TIGR02168
MYND finger; pfam01753
Tudor domain; pfam00567
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
Tudor domain; pfam00567
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
Tudor domain; pfam00567
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
Tudor domain; pfam00567
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
von Willebrand factor (vWF) type A domain; equivalent to the I-domain of integrins.  This domain has a variety of functions including: intermolecular adhesion, cell migration, signalling, transcription, and DNA repair. In integrins these domains form...; cd01472
Epidermal growth factor domain, found in epidermal growth factor (EGF) presents in a large number of proteins, mostly animal; the list of proteins currently known to contain one or more copies of an EGF-like pattern is large and varied; the functional...; cd00053
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
The first LIM domain of actin binding LIM (abLIM) proteins; cd09327
The second LIM domain on actin binding LIM (abLIM) proteins; cd09328
The third LIM domain of actin binding LIM (abLIM) proteins; cd09329
The fourth LIM domain of actin binding LIM (abLIM) proteins; cd09330
Villin headpiece domain; pfam02209
The first LIM domain of actin binding LIM (abLIM) proteins; cd09327
The second LIM domain on actin binding LIM (abLIM) proteins; cd09328
The third LIM domain of actin binding LIM (abLIM) proteins; cd09329
The fourth LIM domain of actin binding LIM (abLIM) proteins; cd09330
Villin headpiece domain; pfam02209
The first LIM domain of actin binding LIM (abLIM) proteins; cd09327
The second LIM domain on actin binding LIM (abLIM) proteins; cd09328
The third LIM domain of actin binding LIM (abLIM) proteins; cd09329
The fourth LIM domain of actin binding LIM (abLIM) proteins; cd09330
Villin headpiece domain; pfam02209
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
Villin headpiece domain; pfam02209
Retinoic acid induced 16-like protein; pfam10257
Retinoic acid induced 16-like protein; pfam10257
Pseudouridine synthase homolog 4; cd02867
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Delta serrate ligand; pfam01414
Galactose oxidase, central domain; cl02701
Kelch motif; pfam13854
Galactose oxidase, central domain; pfam13415
Galactose oxidase, central domain; pfam13418
Kelch motif; pfam13854
Plexin repeat; cl02601
C-type lectin-like domain (CTLD) of the type found in human and mouse attractin (AtrN) and attractin-like protein (ALP); cd03597
Plexin repeat; pfam01437
Plexin repeat; cl02601
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
GDNF/GAS1 domain; pfam02351
GDNF/GAS1 domain; pfam02351
GDNF/GAS1 domain; pfam02351
GDNF/GAS1 domain; pfam02351
GDNF/GAS1 domain; pfam02351
GDNF/GAS1 domain; pfam02351
GDNF/GAS1 domain; pfam02351
GDNF/GAS1 domain; pfam02351
GDNF/GAS1 domain; pfam02351
chromosome segregation protein SMC, common bacterial type; TIGR02168
Lipase; pfam00151
Pancreatic lipase-like enzymes.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is 'interfacial activation,' the...; cd00707
PLAT/LH2 domain of pancreatic triglyceride lipase. Lipases hydrolyze phospholipids and triglycerides to generate fatty acids for energy production or for storage and to release inositol phosphates that act as second messengers. The central role of...; cd01759
Lipase; pfam00151
Pancreatic lipase-like enzymes.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is 'interfacial activation,' the...; cd00707
PLAT/LH2 domain of pancreatic triglyceride lipase. Lipases hydrolyze phospholipids and triglycerides to generate fatty acids for energy production or for storage and to release inositol phosphates that act as second messengers. The central role of...; cd01759
Lipase; pfam00151
Pancreatic lipase-like enzymes.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is 'interfacial activation,' the...; cd00707
PLAT/LH2 domain of pancreatic triglyceride lipase. Lipases hydrolyze phospholipids and triglycerides to generate fatty acids for energy production or for storage and to release inositol phosphates that act as second messengers. The central role of...; cd01759
Lipase; pfam00151
Pancreatic lipase-like enzymes.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is 'interfacial activation,' the...; cd00707
PLAT/LH2 domain of pancreatic triglyceride lipase. Lipases hydrolyze phospholipids and triglycerides to generate fatty acids for energy production or for storage and to release inositol phosphates that act as second messengers. The central role of...; cd01759
Nucleotide-binding domain of HSPA12A and similar proteins; cd11735
TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; cl09108
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
chromosome segregation protein SMC, common bacterial type; TIGR02168
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
chromosome segregation protein SMC, common bacterial type; TIGR02168
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain-containing transcription factor [Transcription]
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Ion channel; pfam07885
Ion channel; pfam07885
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Major Facilitator Superfamily; pfam07690
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
C2 domain found in Rab11-family interacting proteins (FIP) class I; cd08682
FIP domain; pfam09457
7 transmembrane receptor (rhodopsin family); pfam00001
Cullin family; pfam00888
Nanos RNA binding domain; pfam05741
PCI/PINT associated module; smart00753
DENN (AEX-3) domain; cl11519
Tricarboxylate carrier; cl04275
tryparedoxin peroxidase; Provisional
Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; cd03015
tryparedoxin peroxidase; Provisional
Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; cd03015
Regulator of G protein signaling domain (RGS) found in G protein-coupled receptor kinase 5 (GRK5); cd08752
Catalytic domain of G protein-coupled Receptor Kinase 4-like Protein Serine/Threonine Kinases; cd05605
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein kinase C terminal domain; cl11395
Regulator of G protein signaling (RGS) domain found in the R12 subfamily of proteins; cd08706
Regulator of G protein signaling (RGS) domain found in the R12 subfamily of proteins; cd08706
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
BAG domain; pfam02179
Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
SacI homology domain; pfam02383
Inositol phosphatase; pfam12456
SacI homology domain; pfam02383
Inositol phosphatase; pfam12456
Mini-chromosome maintenance replisome factor; pfam09739
Putative alanine racemase; pfam13615
Mini-chromosome maintenance replisome factor; pfam09739
Putative alanine racemase; pfam13615
Putative alanine racemase; pfam13615
SAM domain of sec23ip; cd09584
Sterile alpha motif; smart00454
DDHD domain; pfam02862
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both...; cd03390
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor; cd05857
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2); cd05858
Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 2; cd05101
Protein tyrosine kinase; pfam07714
Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor; cd05857
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2); cd05858
Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 2; cd05101
Protein tyrosine kinase; pfam07714
Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor; cd05857
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2); cd05858
Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 2; cd05101
Protein tyrosine kinase; pfam07714
Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor; cd05857
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2); cd05858
Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 2; cd05101
Protein tyrosine kinase; pfam07714
First immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR); cd04973
Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor; cd05857
Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 2; cd05101
Protein tyrosine kinase; pfam07714
First immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR); cd04973
Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor; cd05857
Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR); cd04974
Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 2; cd05101
Protein tyrosine kinase; pfam07714
First immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR); cd04973
Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor; cd05857
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2); cd05858
Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 2; cd05101
Protein tyrosine kinase; pfam07714
First immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR); cd04973
Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor; cd05857
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 2; cd05101
Protein tyrosine kinase; pfam07714
Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor; cd05857
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 2; cd05101
Protein tyrosine kinase; pfam07714
First immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR); cd04973
Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor; cd05857
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 2; cd05101
Protein tyrosine kinase; pfam07714
Arginine-tRNA-protein transferase, N terminus; pfam04376
Arginine-tRNA-protein transferase, C terminus; pfam04377
Arginine-tRNA-protein transferase, N terminus; pfam04376
Arginine-tRNA-protein transferase, C terminus; pfam04377
Nse4; pfam08743
Nse4; pfam08743
Transforming acidic coiled-coil-containing protein (TACC); pfam05010
ATP synthase B/B' CF(0); cl07975
Transforming acidic coiled-coil-containing protein (TACC); pfam05010
Transforming acidic coiled-coil-containing protein (TACC); pfam05010
Transforming acidic coiled-coil-containing protein (TACC); pfam05010
BTB/POZ domain; cl02518
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
Insulin growth factor-binding protein homologues; smart00121
Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cd00104
Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; COG0265
Trypsin-like peptidase domain; pfam13365
PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; cd00987
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Scavenger receptor Cys-rich; smart00202
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Zona pellucida (ZP) domain; smart00241
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Scavenger receptor Cys-rich; smart00202
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Zona pellucida (ZP) domain; smart00241
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Scavenger receptor Cys-rich; smart00202
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Zona pellucida (ZP) domain; smart00241
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Zona pellucida (ZP) domain; smart00241
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
AAA domain; pfam13671
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Acyl-CoA dehydrogenases [Lipid metabolism]; COG1960
Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; cd01158
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
7 transmembrane receptor (rhodopsin family); pfam00001
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Peptidase M14 carboxypeptidase subfamily N/E-like; Carboxypeptidase X subgroup; cd03869
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; cd11308
Sulfotransferase family; pfam13469
Sulfotransferase family; pfam13469
Sulfotransferase family; pfam13469
Sulfotransferase family; pfam13469
ornithine aminotransferase; TIGR01885
Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; cd00610
Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; cd00610
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
HAD-superfamily subfamily IIA hydrolase, TIGR01458
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
HAD-hyrolase-like; pfam13242
HAD-superfamily subfamily IIA hydrolase, TIGR01458
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
Methyltransferase domain; pfam13489
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Tropomyosin; pfam00261
Zinc finger domain; smart00547
Zinc finger domain; smart00547
Zinc finger domain; smart00547
OTU-like cysteine protease; pfam02338
D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; pfam00389
D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; pfam02826
D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; pfam00389
D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; pfam02826
D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; pfam00389
D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; pfam02826
Putative peptidoglycan binding domain; pfam01471
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate...; cd04278
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; cd06578
Uroporphyrinogen-III synthase HemD; pfam02602
p21-C-terminal region-binding protein; pfam13862
p21-C-terminal region-binding protein; pfam13862
p21-C-terminal region-binding protein; pfam13862
HrpA-like helicases [DNA replication, recombination, and repair]; COG1643
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase associated domain (HA2); pfam04408
Oligonucleotide/oligosaccharide-binding (OB)-fold; pfam07717
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Ankyrin repeats (many copies); pfam13637
Ankyrin repeat; pfam00023
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family; cd04269
Disintegrin; pfam00200
ADAM Cysteine-Rich Domain; smart00608
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family; cd04269
Disintegrin; pfam00200
ADAM Cysteine-Rich Domain; smart00608
Src Homology 3 domain of Class A Dedicator of Cytokinesis proteins 1 and 5; cd12051
C2 domains found in Dedicator Of CytoKinesis (Dock) class A proteins; cd08694
Dock Homology Region 2, a GEF domain, of Class A Dedicator of Cytokinesis 1; cd11707
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
PMP-22/EMP/MP20/Claudin family; cl15797
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
FOG: FHA domain [Signal transduction mechanisms]
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
FOG: FHA domain [Signal transduction mechanisms]
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
K167R (NUC007) repeat; pfam08065
6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; pfam02870
Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; COG0350
The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; cd06445
Colier/Olf/Early B-cell factor (EBF) DNA Binding Domain; cd11606
IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved...; cd01175
TRX domain, PICOT (for PKC-interacting cousin of TRX) subfamily; PICOT is a protein that interacts with protein kinase C (PKC) theta, a calcium independent PKC isoform selectively expressed in skeletal muscle and T lymphocytes. PICOT contains an...; cd02984
Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; cd03028
Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; cd03028
TRX domain, PICOT (for PKC-interacting cousin of TRX) subfamily; PICOT is a protein that interacts with protein kinase C (PKC) theta, a calcium independent PKC isoform selectively expressed in skeletal muscle and T lymphocytes. PICOT contains an...; cd02984
Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; cd03028
Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; cd03028
Domain with 2 conserved Trp (W) residues; smart00456
FF domain; pfam01846
FF domain; cl02610
Serine/threonine protein phosphatase 2A, regulatory subunit [Signal transduction mechanisms]; COG5170
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
BNIP3; pfam06553
SH3 domain protein; TIGR04211
D-hydantoinase; TIGR02033
D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; cd01314
Catalytic domain of the Protein Serine/Threonine Kinase, Yank1; cd05578
Serine/Threonine protein kinases, catalytic domain; smart00220
Leucine rich repeat; pfam13855
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine Rich repeats (2 copies); pfam12799
The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis.  In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in...; cd05835
Type I inositol polyphosphate 5-phosphatase I; cd09092
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
7 transmembrane receptor (Secretin family); cl12142
kinase non-catalytic C-lobe domain; smart00750
kinase non-catalytic C-lobe domain; smart00750
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
RasGEF domain; pfam00617
Myb/SANT-like DNA-binding domain; pfam13837
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family; cd04269
Disintegrin; pfam00200
ADAM Cysteine-Rich Domain; smart00608
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family; cd04269
Disintegrin; pfam00200
ADAM Cysteine-Rich Domain; smart00608
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family; cd04269
Disintegrin; pfam00200
ADAM Cysteine-Rich Domain; smart00608
Spc97 / Spc98 family; pfam04130
Spc97 / Spc98 family; pfam04130
Spc97 / Spc98 family; pfam04130
D1 dopamine receptor-interacting protein (calcyon); pfam06387
RbsD / FucU transport protein family; pfam05025
RbsD / FucU transport protein family; pfam05025
enoyl-CoA hydratase; Provisional
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; cd06558
polyamine oxidase
NAD(P)-binding Rossmann-like domain; pfam13450
polyamine oxidase
NAD(P)-binding Rossmann-like domain; pfam13450
polyamine oxidase
NAD(P)-binding Rossmann-like domain; pfam13450
GTPase YlqF; Reviewed; PRK09563
Circularly permuted YlqF GTPase; cd01856
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
chromosome segregation protein SMC, common bacterial type; TIGR02168
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
chromosome segregation protein SMC, common bacterial type; TIGR02168
Secretoglobins are relatively small, secreted, disulphide-bridged dimeric proteins with encoding genes sharing substantial sequence similarity. Their family subunits may be grouped into five subfamilies, A-E. Uteroglobin (subfamily A), which is identical...; cd00633
SNARE domain; pfam05739
Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in...; cl00152
Guanine nucleotide exchange factor synembryn; pfam10165
NAD-dependent deacetylase; Provisional
SIRT1: Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2...; cd01408
SIRT1: Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2...; cd01408
NAD-dependent deacetylase; Provisional
PCI/PINT associated module; smart00753
PCI/PINT associated module; smart00753
Pyrin Death Domain found in ASC; cd08321
NACHT domain; pfam05729
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Uncharacterized conserved protein (DUF2152); pfam10222
Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; COG1554
Glycosyl hydrolase family 65 central catalytic domain; pfam03632
Interferon-induced transmembrane protein; pfam04505
Interferon-induced transmembrane protein; pfam04505
Interferon-induced transmembrane protein; pfam04505
Interferon-induced transmembrane protein; pfam04505
PA14 domain; cl08459
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; cd00761
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Immunoglobulin I-set domain; pfam07679
TIR domain; cl15770
Immunoglobulin I-set domain; pfam07679
TIR domain; cl15770
Immunoglobulin I-set domain; pfam07679
TIR domain; cl15770
Calcium-activated chloride channel; pfam04547
Phosphatidyl serine synthase; pfam03034
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Leucine rich repeat, ribonuclease inhibitor type; smart00368
Leucine rich repeat, ribonuclease inhibitor type; smart00368
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Leucine rich repeat, ribonuclease inhibitor type; smart00368
Leucine rich repeat, ribonuclease inhibitor type; smart00368
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Leucine rich repeat, ribonuclease inhibitor type; smart00368
Leucine rich repeat, ribonuclease inhibitor type; smart00368
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Leucine rich repeat, ribonuclease inhibitor type; smart00368
Leucine rich repeat, ribonuclease inhibitor type; smart00368
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Leucine rich repeat, ribonuclease inhibitor type; smart00368
Leucine rich repeat, ribonuclease inhibitor type; smart00368
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Leucine rich repeat, ribonuclease inhibitor type; smart00368
Leucine rich repeat, ribonuclease inhibitor type; smart00368
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Leucine rich repeat, ribonuclease inhibitor type; smart00368
Leucine rich repeat, ribonuclease inhibitor type; smart00368
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Leucine rich repeat, ribonuclease inhibitor type; smart00368
Leucine rich repeat, ribonuclease inhibitor type; smart00368
GTPase SAR1 and related small G proteins [General function prediction only]
Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B; cd04138
GTPase SAR1 and related small G proteins [General function prediction only]
Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B; cd04138
GTPase SAR1 and related small G proteins [General function prediction only]
Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B; cd04138
Leucine rich repeat; pfam13855
Lamin Tail Domain; pfam00932
Ras association (RalGDS/AF-6) domain; smart00314
Ras association (RalGDS/AF-6) domain; smart00314
Ras association (RalGDS/AF-6) domain; smart00314
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
PHD-finger; pfam00628
Interferon Regulatory Factor (IRF); also known as tryptophan pentad repeat. The family of IRF transcription factors is important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. The...; cd00103
Interferon-regulatory factor 3; pfam10401
Interferon Regulatory Factor (IRF); also known as tryptophan pentad repeat. The family of IRF transcription factors is important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. The...; cd00103
Interferon-regulatory factor 3; pfam10401
Interferon Regulatory Factor (IRF); also known as tryptophan pentad repeat. The family of IRF transcription factors is important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. The...; cd00103
Interferon-regulatory factor 3; pfam10401
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Glucagon like hormones; smart00070
7 transmembrane receptor (rhodopsin family); pfam00001
SAND domain; pfam01342
MYND finger; pfam01753
Predicted membrane protein; pfam09799
Predicted membrane protein; pfam09799
Phosphotyrosine-binding domain; pfam08416
Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins; cd11764
SAM domain of EPS8-like subfamily; cd09540
transaldolase-like protein; Provisional
Transaldolases including both TalA and TalB; cd00957
Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; cd03141
Putative intracellular protease/amidase [General function prediction only]; COG0693
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Leucine rich repeat; pfam13855
Peptidase S68; pfam10461
ZU5 domain; cl02517
Death Domain of p53-induced protein with a death domain; cd08779
Leucine rich repeat; pfam13855
Peptidase S68; pfam10461
ZU5 domain; cl02517
Death Domain of p53-induced protein with a death domain; cd08779
Ribosomal protein P2. This subfamily represents the eukaryotic large ribosomal protein P2. Eukaryotic P1 and P2 are functionally equivalent to the bacterial protein L7/L12, but are not homologous to L7/L12. P2 is located in the L12 stalk, with proteins...; cd05833
Patatin-like phospholipase domain containing protein 2; cd07220
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), CD151_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model...; cd03155
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), CD151_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model...; cd03155
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), CD151_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model...; cd03155
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), CD151_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model...; cd03155
DNA-directed RNA polymerase; Provisional
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model...; cd03165
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model...; cd03165
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model...; cd03165
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model...; cd03165
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model...; cd03165
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model...; cd03165
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model...; cd03165
Stabilin-1 interacting chitinase-like protein (SI-CLP) is a eukaryotic chitinase-like protein of unknown function that interacts with the endocytic/sorting transmembrane receptor stabilin-1 and is secreted from the lysosome.  SI-CLP has a glycosyl...; cd02876
Glyco_18 domain; smart00636
Stabilin-1 interacting chitinase-like protein (SI-CLP) is a eukaryotic chitinase-like protein of unknown function that interacts with the endocytic/sorting transmembrane receptor stabilin-1 and is secreted from the lysosome.  SI-CLP has a glycosyl...; cd02876
Glyco_18 domain; smart00636
Stabilin-1 interacting chitinase-like protein (SI-CLP) is a eukaryotic chitinase-like protein of unknown function that interacts with the endocytic/sorting transmembrane receptor stabilin-1 and is secreted from the lysosome.  SI-CLP has a glycosyl...; cd02876
Glyco_18 domain; smart00636
Stabilin-1 interacting chitinase-like protein (SI-CLP) is a eukaryotic chitinase-like protein of unknown function that interacts with the endocytic/sorting transmembrane receptor stabilin-1 and is secreted from the lysosome.  SI-CLP has a glycosyl...; cd02876
Glyco_18 domain; smart00636
Stabilin-1 interacting chitinase-like protein (SI-CLP) is a eukaryotic chitinase-like protein of unknown function that interacts with the endocytic/sorting transmembrane receptor stabilin-1 and is secreted from the lysosome.  SI-CLP has a glycosyl...; cd02876
Glyco_18 domain; smart00636
Adaptin N terminal region; pfam01602
Adaptin C-terminal domain; smart00809
Alpha adaptin AP2, C-terminal domain; pfam02296
Adaptin N terminal region; pfam01602
Adaptin C-terminal domain; smart00809
Alpha adaptin AP2, C-terminal domain; pfam02296
von Willebrand factor type D domain; pfam00094
C8 domain; pfam08742
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor type C domain; cl02515
von Willebrand factor (vWF) type D domain; smart00216
C8 domain; pfam08742
Trypsin Inhibitor like cysteine rich domain; pfam01826
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor (vWF) type D domain; smart00216
C8 domain; pfam08742
C-terminal cystine knot-like domain (CTCK); smart00041
von Willebrand factor type D domain; pfam00094
C8 domain; pfam08742
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor (vWF) type D domain; smart00216
This domain contains 8 conserved cysteine residues; smart00832
von Willebrand factor (vWF) type D domain; smart00216
C8 domain; pfam08742
Mucin-2 protein WxxW repeating region; pfam13330
Mucin-2 protein WxxW repeating region; pfam13330
von Willebrand factor (vWF) type D domain; smart00216
C8 domain; pfam08742
von Willebrand factor (vWF) type C domain; smart00214
Cystine-knot domain; pfam00007
von Willebrand factor (vWF) type D domain; smart00216
C8 domain; pfam08742
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor (vWF) type D domain; smart00216
This domain contains 8 conserved cysteine residues; smart00832
Trypsin Inhibitor like cysteine rich domain; pfam01826
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor (vWF) type D domain; smart00216
C8 domain; pfam08742
Mucin-2 protein WxxW repeating region; pfam13330
Mucin-2 protein WxxW repeating region; pfam13330
Mucin-2 protein WxxW repeating region; pfam13330
Mucin-2 protein WxxW repeating region; pfam13330
Mucin-2 protein WxxW repeating region; pfam13330
Mucin-2 protein WxxW repeating region; pfam13330
Mucin-2 protein WxxW repeating region; pfam13330
von Willebrand factor (vWF) type D domain; smart00216
C8 domain; pfam08742
von Willebrand factor (vWF) type C domain; smart00214
C-terminal cystine knot-like domain (CTCK); smart00041
C2 domain present in Toll-interacting protein (Tollip); cd04016
Domain that may be involved in binding ubiquitin-conjugating enzymes (UBCs); smart00546
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Mob1/phocein family; pfam03637
Mob1/phocein family; pfam03637
N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by...; cd01446
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
Interferon-induced transmembrane protein; pfam04505
A1 Propeptide; pfam07966
Cathepsin_D2, pepsin family of proteinases; cd05490
Eukaryotic aspartyl protease; pfam00026
C2 domain; cl14603
C2 domain; cl14603
Troponin; pfam00992
Troponin; pfam00992
Troponin; pfam00992
Caldesmon; pfam02029
Caldesmon; pfam02029
Caldesmon; pfam02029
Caldesmon; pfam02029
Caldesmon; pfam02029
Caldesmon; pfam02029
Troponin; pfam00992
Troponin; pfam00992
Troponin; pfam00992
Troponin; pfam00992
Ribosomal protein L23; cl00326
nucleotidyl transferase superfamily; cl00015
IlGF, insulin_like growth factors; specific to vertebrates. Members include a number of peptides including insulin-like growth factors I and II, which play a variety of roles in controlling processes such as growth, differentiation, and reproduction. On...; cd04368
Insulin-like growth factor II E-peptide; pfam08365
IlGF, insulin_like growth factors; specific to vertebrates. Members include a number of peptides including insulin-like growth factors I and II, which play a variety of roles in controlling processes such as growth, differentiation, and reproduction. On...; cd04368
Insulin-like growth factor II E-peptide; pfam08365
IlGF, insulin_like growth factors; specific to vertebrates. Members include a number of peptides including insulin-like growth factors I and II, which play a variety of roles in controlling processes such as growth, differentiation, and reproduction. On...; cd04368
Insulin-like growth factor II E-peptide; pfam08365
IlGF_like family, insulin_like subgroup, specific to vertebrates. Members include a number of peptides including insulin and insulin-like growth factors I and II, which play a variety of roles in controlling processes such as metabolism, growth and...; cd04367
IlGF_like family, insulin_like subgroup, specific to vertebrates. Members include a number of peptides including insulin and insulin-like growth factors I and II, which play a variety of roles in controlling processes such as metabolism, growth and...; cd04367
IlGF_like family, insulin_like subgroup, specific to vertebrates. Members include a number of peptides including insulin and insulin-like growth factors I and II, which play a variety of roles in controlling processes such as metabolism, growth and...; cd04367
IlGF_like family, insulin_like subgroup, specific to vertebrates. Members include a number of peptides including insulin and insulin-like growth factors I and II, which play a variety of roles in controlling processes such as metabolism, growth and...; cd04367
Tyrosine hydroxylase N terminal; pfam12549
tyrosine 3-monooxygenase, tetrameric; TIGR01269
ACT domain of the nonheme iron-dependent aromatic amino acid hydroxylase, tyrosine hydroxylases (TH); cd04930
Eukaryotic tyrosine hydroxylase (TyrOH); a member of the biopterin-dependent aromatic amino acid hydroxylase family of non-heme, iron(II)-dependent enzymes that also includes prokaryotic and eukaryotic phenylalanine-4-hydroxylase (PheOH) and eukaryotic...; cd03345
Tyrosine hydroxylase N terminal; pfam12549
tyrosine 3-monooxygenase, tetrameric; TIGR01269
ACT domain of the nonheme iron-dependent aromatic amino acid hydroxylase, tyrosine hydroxylases (TH); cd04930
Eukaryotic tyrosine hydroxylase (TyrOH); a member of the biopterin-dependent aromatic amino acid hydroxylase family of non-heme, iron(II)-dependent enzymes that also includes prokaryotic and eukaryotic phenylalanine-4-hydroxylase (PheOH) and eukaryotic...; cd03345
Tyrosine hydroxylase N terminal; pfam12549
tyrosine 3-monooxygenase, tetrameric; TIGR01269
ACT domain of the nonheme iron-dependent aromatic amino acid hydroxylase, tyrosine hydroxylases (TH); cd04930
Eukaryotic tyrosine hydroxylase (TyrOH); a member of the biopterin-dependent aromatic amino acid hydroxylase family of non-heme, iron(II)-dependent enzymes that also includes prokaryotic and eukaryotic phenylalanine-4-hydroxylase (PheOH) and eukaryotic...; cd03345
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), PHEMX_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model...; cd03153
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), CD81_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment...; cd03151
transient-receptor-potential calcium channel protein; TIGR00870
Ion transport protein; pfam00520
Ion channel; pfam07885
KCNQ voltage-gated potassium channel; pfam03520
Cyclin-dependent kinase inhibitor; pfam02234
Cyclin-dependent kinase inhibitor; pfam02234
Cyclin-dependent kinase inhibitor; pfam02234
Major Facilitator Superfamily; pfam07690
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Major Facilitator Superfamily; pfam07690
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Pleckstrin homology (PH) domain; cd00821
(NAP-L) nucleosome assembly protein -L; Provisional; cl08298
Nucleosome assembly protein (NAP); pfam00956
catalytic core domain of cysteinyl tRNA synthetase; cd00672
nucleotidyl transferase superfamily; cl00015
cysteinyl-tRNA-synthetase; Provisional
catalytic core domain of cysteinyl tRNA synthetase; cd00672
Glutathione S-transferase C-terminal-like, alpha helical domain of Cysteinyl-tRNA synthetase from higher eukaryotes; cd10310
catalytic core domain of cysteinyl tRNA synthetase; cd00672
nucleotidyl transferase superfamily; cl00015
cysteinyl-tRNA-synthetase; Provisional
catalytic core domain of cysteinyl tRNA synthetase; cd00672
catalytic core domain of cysteinyl tRNA synthetase; cd00672
nucleotidyl transferase superfamily; cl00015
cysteinyl-tRNA-synthetase; Provisional
catalytic core domain of cysteinyl tRNA synthetase; cd00672
Glutathione S-transferase C-terminal-like, alpha helical domain of Cysteinyl-tRNA synthetase from higher eukaryotes; cd10310
catalytic core domain of cysteinyl tRNA synthetase; cd00672
nucleotidyl transferase superfamily; cl00015
cysteinyl-tRNA-synthetase; Provisional
catalytic core domain of cysteinyl tRNA synthetase; cd00672
Pleckstrin homology-like domain; cl00273
Oxysterol-binding protein; pfam01237
Pleckstrin homology-like domain; cl00273
Oxysterol-binding protein; pfam01237
Oxysterol binding protein (OSBP) Pleckstrin homology (PH) domain; cd01246
Oxysterol-binding protein; pfam01237
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
NAD:arginine ADP-ribosyltransferase; pfam01129
NAD:arginine ADP-ribosyltransferase; pfam01129
NAD:arginine ADP-ribosyltransferase; pfam01129
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Nucleoporin FG repeat region; pfam13634
Nucleoporin FG repeat region; pfam13634
Nucleoporin autopeptidase; pfam04096
Nuclear protein 96; pfam12110
Nuclear protein 96; pfam12110
Nucleoporin FG repeat region; pfam13634
Nucleoporin FG repeat region; pfam13634
Nucleoporin FG repeat region; pfam13634
Nucleoporin autopeptidase; pfam04096
Nuclear protein 96; pfam12110
Nucleoporin autopeptidase; pfam04096
Nucleoporin autopeptidase; pfam04096
Frag1/DRAM/Sfk1 family; pfam10277
Frag1/DRAM/Sfk1 family; pfam10277
Frag1/DRAM/Sfk1 family; pfam10277
Frag1/DRAM/Sfk1 family; pfam10277
Frag1/DRAM/Sfk1 family; pfam10277
Frag1/DRAM/Sfk1 family; pfam10277
Frag1/DRAM/Sfk1 family; pfam10277
Frag1/DRAM/Sfk1 family; pfam10277
Ras homolog family, member G (RhoG) of small guanosine triphosphatases (GTPases); cd01875
GTPase SAR1 and related small G proteins [General function prediction only]
SAM domain of STIM1 subfamily proteins; cd09573
SAM domain (Sterile alpha motif); pfam07647
ATP synthase B/B' CF(0); cl07975
STIM1 Orai1-activating region; cd11722
ribonucleoside--diphosphate reductase large subunit
ATP cone domain; pfam03477
Class I ribonucleotide reductase; cd01679
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
associated with SPRY domains; smart00589
Domain in SPla and the RYanodine Receptor; smart00449
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
associated with SPRY domains; smart00589
Domain in SPla and the RYanodine Receptor; smart00449
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate...; cd04278
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; cd01040
Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; cd01040
Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; cd01040
Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; cd01040
Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; cd01040
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Ubiquitin-like domain of hPLIC-1 and hPLIC2; cd01808
Ubiquitin family; pfam00240
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Ubiquitin homologues; smart00213
Ubiquitin-like proteins; cl00155
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
SPRY-associated domain; cl02686
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
SPRY-associated domain; cl02686
Domain in SPla and the RYanodine Receptor; smart00449
SPRY-associated domain; cl02686
Domain in SPla and the RYanodine Receptor; smart00449
SPRY-associated domain; cl02686
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
Domain in SPla and the RYanodine Receptor; smart00449
Olfactory receptor; cl10458
Olfactory receptor; cl10458
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Retinoic acid induced 16-like protein; pfam10257
Retinoic acid induced 16-like protein; pfam10257
Voltage-dependent potassium channel; Provisional
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
7 transmembrane receptor (rhodopsin family); pfam00001
Saposin (B) Domains; smart00741
acid sphingomyelinase and related proteins, metallophosphatase domain; cd00842
Calcineurin-like phosphoesterase; pfam00149
Saposin (B) Domains; smart00741
acid sphingomyelinase and related proteins, metallophosphatase domain; cd00842
Calcineurin-like phosphoesterase; pfam00149
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
WW domain; pfam00397
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
WW domain; pfam00397
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
WW domain; pfam00397
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Pleckstrin homology-like domain; cl00273
WW domain; pfam00397
Pleckstrin homology-like domain; cl00273
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
Plasmid replication region DNA-binding N-term; pfam11740
B-Box C-terminal domain; smart00502
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
NHL repeat; pfam01436
Uncharacterized conserved protein [Function unknown]
NHL repeat; pfam01436
NHL repeat; pfam01436
NHL repeat; pfam01436
NHL repeat; pfam01436
NHL repeat; pfam01436
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
Plasmid replication region DNA-binding N-term; pfam11740
B-Box C-terminal domain; smart00502
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
NHL repeat; pfam01436
Uncharacterized conserved protein [Function unknown]
NHL repeat; pfam01436
NHL repeat; pfam01436
NHL repeat; pfam01436
NHL repeat; pfam01436
NHL repeat; pfam01436
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
Plasmid replication region DNA-binding N-term; pfam11740
B-Box C-terminal domain; smart00502
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
NHL repeat; pfam01436
Uncharacterized conserved protein [Function unknown]
NHL repeat; pfam01436
NHL repeat; pfam01436
NHL repeat; pfam01436
NHL repeat; pfam01436
NHL repeat; pfam01436
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
Plasmid replication region DNA-binding N-term; pfam11740
B-Box C-terminal domain; smart00502
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
NHL repeat; pfam01436
Uncharacterized conserved protein [Function unknown]
NHL repeat; pfam01436
NHL repeat; pfam01436
NHL repeat; pfam01436
NHL repeat; pfam01436
NHL repeat; pfam01436
Arfaptin-like domain; pfam06456
The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin; cd07660
Arfaptin-like domain; pfam06456
The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin; cd07660
Arfaptin-like domain; pfam06456
The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin; cd07660
Arfaptin-like domain; pfam06456
The Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin; cd07660
Tim10/DDP family zinc finger; pfam02953
Dynein heavy chain, N-terminal region 2; pfam08393
Hydrolytic ATP binding site of dynein motor region D1; pfam12774
Microtubule-binding stalk of dynein motor; pfam12777
Methyltransferase domain; pfam13489
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Protein tyrosine kinase; pfam07714
Protein Kinases, catalytic domain; cl09925
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Protein tyrosine kinase; pfam07714
Protein Kinases, catalytic domain; cl09925
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Protein tyrosine kinase; pfam07714
Protein Kinases, catalytic domain; cl09925
The TATA Binding Protein (TBP) Associated Factor 10; cd07982
Activation domain of S53 peptidases; cd11377
Peptidase domain in the S53 family; cd04056
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Ribosomal protein L17; pfam01196
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
SCAN oligomerization domain; cd07936
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Pyrin death domain found in NALP proteins; cd08320
ATPases associated with a variety of cellular activities; smart00382
NACHT domain; pfam05729
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
C2 domain; cl14603
C2 domain second repeat present in Synaptotagmins 3, 5, 6, 9, and 10; cd08403
Olfactomedin-like domain; pfam02191
DNA binding domain of tn916 integrase; pfam02920
Sterile alpha motif; smart00454
SAM domain of liprin-beta1,2 proteins repeat 1; cd09563
SAM domain of liprin-beta1,2 proteins repeat 2; cd09566
Sterile alpha motif; smart00454
SAM domain of liprin-beta proteins repeat 3; cd09569
SAM domain (Sterile alpha motif); pfam07647
DNA binding domain of tn916 integrase; pfam02920
Sterile alpha motif; smart00454
SAM domain of liprin-beta1,2 proteins repeat 1; cd09563
SAM domain of liprin-beta1,2 proteins repeat 2; cd09566
Sterile alpha motif; smart00454
SAM domain of liprin-beta proteins repeat 3; cd09569
SAM domain (Sterile alpha motif); pfam07647
DNA binding domain of tn916 integrase; pfam02920
Sterile alpha motif; smart00454
SAM domain of liprin-beta1,2 proteins repeat 1; cd09563
SAM domain of liprin-beta1,2 proteins repeat 2; cd09566
Sterile alpha motif; smart00454
SAM domain of liprin-beta proteins repeat 3; cd09569
SAM domain (Sterile alpha motif); pfam07647
NADH-cytochrome B5 reductase; Provisional
Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a...; cd06183
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Pyrin Death Domain found in ASC; cd08321
ATPases associated with a variety of cellular activities; smart00382
NACHT domain; pfam05729
Mpr1p, Pad1p N-terminal (MPN) domains without catalytic isopeptidase activity, found in eIF3f; cd08064
Tub family; pfam01167
Tub family; pfam01167
The first LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3); cd09388
The second LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3); cd09389
The first LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3); cd09388
The second LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3); cd09389
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
PHD-finger; pfam00628
Bromodomain; tif1_like subfamily. Tif1 (transcription intermediary factor 1) is a member of the tripartite motif (TRIM) protein family, which is characterized by a particular domain architecture. It functions by recruiting coactivators and/or...; cd05502
60S ribosomal protein L27a; Provisional
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
DENN (AEX-3) domain; pfam02141
dDENN domain; pfam03455
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
DENN (AEX-3) domain; pfam02141
dDENN domain; pfam03455
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
DENN (AEX-3) domain; pfam02141
dDENN domain; pfam03455
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
TMEM9; pfam05434
NRIP_C; putative nuclear receptor interacting protein; cd05480
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Complement Clr-like EGF-like; pfam12662
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
GCC2 and GCC3; pfam07699
GCC2 and GCC3; pfam07699
GCC2 and GCC3; pfam07699
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Complement Clr-like EGF-like; pfam12662
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Calcium-binding EGF-like domain; smart00179
GCC2 and GCC3; pfam07699
GCC2 and GCC3; pfam07699
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
DENN (AEX-3) domain; pfam02141
dDENN domain; pfam03455
domain involved in Ras-like GTPase signaling; smart00593
PLAT/LH2 domain present in RAB6 interacting protein 1 (Rab6IP1)_like family. PLAT/LH2 domains consists of an eight stranded beta-barrel. In RabIP1 this domain may participate in lipid-mediated modulation of Rab6IP1's function via it's generally proposed...; cd01757
RUN domain; cl02689
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
DENN (AEX-3) domain; pfam02141
dDENN domain; pfam03455
domain involved in Ras-like GTPase signaling; smart00593
PLAT/LH2 domain present in RAB6 interacting protein 1 (Rab6IP1)_like family. PLAT/LH2 domains consists of an eight stranded beta-barrel. In RabIP1 this domain may participate in lipid-mediated modulation of Rab6IP1's function via it's generally proposed...; cd01757
SNARE associated Golgi protein; pfam09335
Importin, protein involved in nuclear import [Posttranslational modification, protein turnover, chaperones]; COG5656
Importin-beta N-terminal domain; pfam03810
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Protein kinase domain; pfam00069
Catalytic domain of Protein Kinases; cd00180
Protein kinase domain; pfam00069
Catalytic domain of Protein Kinases; cd00180
Pleckstrin homology (PH) domain; cd00821
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
DENN (AEX-3) domain; pfam02141
Domain always found downstream of DENN domain, found in a variety of signalling proteins; smart00801
Myotubularin protein; pfam12335
GRAM domain; cl02671
Myotubularin-related; pfam06602
Myotubularin Y_phosphatase-like; pfam13849
Set binding factor Pleckstrin Homology (PH) domain; cd01235
Calcitonin / CGRP / IAPP family; pfam00214
AMP deaminase; TIGR01429
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway; cd01319
AMP deaminase; TIGR01429
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway; cd01319
AMP deaminase; TIGR01429
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway; cd01319
AMP deaminase; TIGR01429
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway; cd01319
AMP deaminase; TIGR01429
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway; cd01319
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding...; cd03516
MRVI1 protein; pfam05781
MRVI1 protein; pfam05781
MRVI1 protein; pfam05781
MRVI1 protein; pfam05781
MRVI1 protein; pfam05781
MRVI1 protein; pfam05781
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
MIF4G domain; pfam02854
Domain in DAP-5, eIF4G, MA-3 and other proteins; smart00544
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; cd11559
MIF4G domain; pfam02854
Domain in DAP-5, eIF4G, MA-3 and other proteins; smart00544
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; cd11559
MIF4G domain; pfam02854
Domain in DAP-5, eIF4G, MA-3 and other proteins; smart00544
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; cd11559
BED zinc finger; cl02703
BED zinc finger; cl02703
pp-GalNAc-T initiates the formation of mucin-type O-linked glycans; cd02510
Ricin-type beta-trefoil lectin domain; pfam00652
Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; cd00161
Protein Kinases, catalytic domain; cl09925
Protein kinase domain; pfam00069
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02659
Dickkopf N-terminal cysteine-rich region; pfam04706
Prokineticin; pfam06607
Dickkopf N-terminal cysteine-rich region; pfam04706
Prokineticin; pfam06607
Dickkopf N-terminal cysteine-rich region; pfam04706
Prokineticin; pfam06607
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
FAD binding domain; pfam01494
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
The LIM domain of Mical (molecule interacting with CasL); cd09439
ProQ/FINO family; smart00945
Protein of unknown function (DUF3585); pfam12130
Calponin homology (CH) domain; pfam00307
Calponin homology (CH) domain; pfam00307
TEA/ATTS domain family; pfam01285
Ubiquitin-like proteins; cl00155
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Broad-Complex, Tramtrack and Bric a brac; smart00225
Parathyroid hormone family; pfam01279
fatty acyl-CoA reductase
fatty acyl CoA reductases (FARs), extended (e) SDRs; cd05236
C-terminal domain of fatty acyl CoA reductases; cd09071
Reeler, the N-terminal domain of reelin, F-spondin, and a variety of other proteins; cd08544
Spondin_N; pfam06468
Thrombospondin type 1 domain; cl15278
Thrombospondin type 1 domain; pfam00090
Thrombospondin type 1 domain; pfam00090
Thrombospondin type 1 domain; pfam00090
Thrombospondin type 1 domain; pfam00090
Thrombospondin type 1 domain; pfam00090
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
R-Ras2/TC21, M-Ras/R-Ras3; cd04145
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Adaptin N terminal region; pfam01602
Coatamer beta C-terminal region; pfam07718
Adaptin N terminal region; pfam01602
Coatamer beta C-terminal region; pfam07718
Adaptin N terminal region; pfam01602
Coatamer beta C-terminal region; pfam07718
proteasome subunit alpha; Provisional
proteasome_alpha_type_1. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on...; cd03749
proteasome subunit alpha; Provisional
proteasome_alpha_type_1. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on...; cd03749
The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; cl00467
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Calcitonin / CGRP / IAPP family; pfam00214
calcitonin; smart00113
Calcitonin / CGRP / IAPP family; pfam00214
calcitonin; smart00113
Calcitonin / CGRP / IAPP family; pfam00214
calcitonin; smart00113
Calcitonin / CGRP / IAPP family; pfam00214
calcitonin; smart00113
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Pleckstrin homology (PH) domain; cd00821
Protein of unknown function (DUF1640); pfam07798
Ribosomal S13/S15 N-terminal domain; pfam08069
40S ribosomal protein S13; Provisional
Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; cd00353
PI3-kinase family, ras-binding domain; pfam00794
C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks); cd04012
Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general,  class II PI3-kinases...; cd00869
Phosphoinositide 3-kinase (PI3K), class II, alpha isoform, catalytic domain; The PI3K catalytic domain family is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein...; cd05176
Phosphoinositide 3-kinase, catalytic domain; smart00146
The phosphoinositide binding Phox Homology Domain of the Alpha Isoform of Class II Phosphoinositide 3-Kinases; cd07289
C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks); cd08381
EF-hand domain pair; pfam13499
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Matrix protein (MA), p15; pfam01140
Inward rectifier potassium channel; pfam01007
Ion channel; cl11596
ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; COG1132
ABC transporter transmembrane region; cl00549
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
ABC transporter transmembrane region; pfam00664
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; COG4988
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
N-terminal protein-binding module of harmonin; cd07353
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
N-terminal protein-binding module of harmonin; cd07353
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Basic domain in HLH proteins of MYOD family; smart00520
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Myogenic determination factor 5; pfam12232
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam13540
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
tryptophan 5-monooxygenase, tetrameric; TIGR01270
ACT domain of the nonheme iron-dependent aromatic amino acid hydroxylase, tryptophan hydroxylases (TPH), both peripheral (TPH1) and neuronal (TPH2) enzymes; cd04929
Eukaryotic tryptophan hydroxylase (TrpOH); a member of the biopterin-dependent aromatic amino acid hydroxylase family of non-heme, iron(II)-dependent enzymes that also includes prokaryotic and eukaryotic phenylalanine-4-hydroxylase (PheOH) and eukaryotic...; cd03346
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
Serum amyloid A protein; pfam00277
Serum amyloid A proteins; smart00197
Serum amyloid A proteins; smart00197
Serum amyloid A protein; cl02506
Serum amyloid A protein; pfam00277
Serum amyloid A protein; pfam00277
Serum amyloid A protein; pfam00277
Serum amyloid A protein; pfam00277
TFIIH p62 subunit, N-terminal domain; pfam08567
BSD domain; pfam03909
BSD domain; pfam03909
TFIIH p62 subunit, N-terminal domain; pfam08567
BSD domain; pfam03909
BSD domain; pfam03909
A subgroup of L-lactate dehydrogenases; cd05293
L-lactate dehydrogenase; TIGR01771
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
A subgroup of L-lactate dehydrogenases; cd05293
L-lactate dehydrogenase; TIGR01771
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
lactate/malate dehydrogenase, alpha/beta C-terminal domain; pfam02866
A subgroup of L-lactate dehydrogenases; cd05293
A subgroup of L-lactate dehydrogenases; cd05293
L-lactate dehydrogenase; TIGR01771
A subgroup of L-lactate dehydrogenases; cd05293
L-lactate dehydrogenase; TIGR01771
A subgroup of L-lactate dehydrogenases; cd05293
L-lactate dehydrogenase; TIGR01771
A subgroup of L-lactate dehydrogenases; cd05293
L-lactate dehydrogenase; TIGR01771
UEV domain; pfam05743
Protein of unknown function (DUF1640); pfam07798
Vps23 core domain; pfam09454
UEV domain; pfam05743
lactate dehydrogenase
A subgroup of L-lactate dehydrogenases; cd05293
UEV domain; pfam05743
lactate dehydrogenase
A subgroup of L-lactate dehydrogenases; cd05293
lactate dehydrogenase
A subgroup of L-lactate dehydrogenases; cd05293
UEV domain; pfam05743
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
UEV domain; pfam05743
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
UEV domain; pfam05743
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cl00154
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
SPT2 chromatin protein; smart00784
YhhN-like protein; pfam07947
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin like; smart00410
Immunoglobulin (Ig)-like domain of titin and similar proteins; cd05748
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of titin and similar proteins; cd05748
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13857
DHHC palmitoyltransferase; pfam01529
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
DHHC palmitoyltransferase; pfam01529
The first LIM domain of Cysteine Rich Protein 3 (CRP3/MLP); cd09481
The second LIM domain of Cysteine Rich Protein 3 (CRP3/MLP); cd09482
E2F/DP family winged-helix DNA-binding domain; pfam02319
E2F/DP family winged-helix DNA-binding domain; pfam02319
E2F/DP family winged-helix DNA-binding domain; pfam02319
E2F/DP family winged-helix DNA-binding domain; pfam02319
E2F/DP family winged-helix DNA-binding domain; pfam02319
E2F/DP family winged-helix DNA-binding domain; pfam02319
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
AAA domain; pfam13401
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
AAA domain; pfam13401
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
AAA domain; pfam13401
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
AAA domain; pfam13401
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
AAA domain; pfam13401
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
CC3(TIP30)-like, atypical (a) SDRs; cd05250
NADH(P)-binding; pfam13460
CC3(TIP30)-like, atypical (a) SDRs; cd05250
NADH(P)-binding; pfam13460
CC3(TIP30)-like, atypical (a) SDRs; cd05250
NADH(P)-binding; pfam13460
CC3(TIP30)-like, atypical (a) SDRs; cd05250
NADH(P)-binding; pfam13460
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
NADH(P)-binding; pfam13460
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Na(+)- and Cl(-)-dependent glycine transporter GlyT2; solute-binding domain; cd11499
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
von Willebrand factor type C domain; pfam00093
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
EGF domain; pfam12947
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
von Willebrand factor type C domain; pfam00093
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
EGF domain; pfam12947
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
Calcium-activated chloride channel; pfam04547
Calcium-activated chloride channel; pfam04547
Na(+)-dependent inorganic phosphate cotransporter; TIGR00894
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Fanconi anemia group F protein (FANCF); pfam11107
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Growth-Arrest-Specific Protein 2 Domain; pfam02187
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Growth-Arrest-Specific Protein 2 Domain; pfam02187
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Growth-Arrest-Specific Protein 2 Domain; pfam02187
chromosome segregation protein SMC, common bacterial type; TIGR02168
chromosome segregation protein SMC, primarily archaeal type; TIGR02169
Calcium-activated chloride channel; pfam04547
Na(+)/monocarboxylate cotransporter SMCT2 and related proteins; solute-binding domain; cd11520
Protein of unknown function (DUF971); cl01414
gamma-butyrobetaine hydroxylase; TIGR02409
Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; cd00250
Domain of unknown function (DUF4207); pfam13904
Domain of unknown function (DUF4207); pfam13904
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
G protein-coupled chemokine receptor-like protein; Provisional
L27 domain; pfam02828
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Nerve growth factor family; pfam00243
Nerve growth factor family; pfam00243
Nerve growth factor family; pfam00243
Nerve growth factor family; pfam00243
Nerve growth factor family; pfam00243
Nerve growth factor family; pfam00243
Nerve growth factor family; pfam00243
Nerve growth factor family; pfam00243
Nerve growth factor family; pfam00243
Nerve growth factor family; pfam00243
Nerve growth factor family; pfam00243
Nerve growth factor family; pfam00243
Nerve growth factor family; pfam00243
Nerve growth factor family; pfam00243
Nerve growth factor family; pfam00243
Nerve growth factor family; pfam00243
Nerve growth factor family; pfam00243
Kinesin motor, catalytic domain. ATPase; smart00129
Kinesin motor domain, KIP3-like subgroup. The yeast kinesin KIP3 plays a role in positioning the mitotic spindle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Kinesins are microtubule-dependent...; cd01370
Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]
16S rRNA m(4)C1402 methyltranserfase; Provisional
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
Potassium channel Kv1.4 tandem inactivation domain; pfam07941
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
Glycoprotein hormone beta chain homologues; smart00068
Glycoprotein hormone beta chain homologues; smart00068
Calcineurin-like phosphoesterase; pfam00149
Homo sapiens 239FB and related proteins, metallophosphatase domain; cd07379
metallophosphatase superfamily, metallophosphatase domain; cl13995
Calcineurin-like phosphoesterase; pfam00149
Homo sapiens 239FB and related proteins, metallophosphatase domain; cd07379
Homo sapiens 239FB and related proteins, metallophosphatase domain; cd07379
Ubiquitin-like proteins; cl00155
Ricin-type beta-trefoil lectin domain; pfam00652
Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; cd00161
Ubiquitin-like proteins; cl00155
Ubiquitin-like proteins; cl00155
Ubiquitin-like proteins; cl00155
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]; COG0484
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
CSL zinc finger; pfam05207
The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; cd06530
signal peptidase I, bacterial type; TIGR02227
PAXNEB protein; pfam05625
Paired Box domain; smart00351
Paired Box domain; cd00131
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Paired Box domain; smart00351
Paired Box domain; cd00131
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Paired Box domain; smart00351
Paired Box domain; cd00131
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Paired Box domain; smart00351
Paired Box domain; cd00131
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Paired Box domain; smart00351
Paired Box domain; cd00131
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Paired Box domain; smart00351
Paired Box domain; cd00131
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Paired Box domain; smart00351
Paired Box domain; cd00131
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Wilm's tumour protein; pfam02165
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Wilm's tumour protein; pfam02165
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Wilm's tumour protein; pfam02165
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Wilm's tumour protein; pfam02165
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Wilm's tumour protein; pfam02165
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
PCI/PINT associated module; smart00753
chromosome segregation protein SMC, common bacterial type; TIGR02168
Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain; cl02449
hypothetical protein; Provisional
Domain of unknown function (DUF4211); pfam13926
DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in DEPDC4-like proteins. DEPDC4 is a DEP domain containing protein of unknown function; cd04446
RhoGAP_BRCC3-like: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of BRCC3-like proteins. This subgroup also contains two groups of closely related proteins, BRCC3 and DEPDC7, which both contain a C-terminal RhoGAP-like domain...; cd04405
DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in DEPDC4-like proteins. DEPDC4 is a DEP domain containing protein of unknown function; cd04446
RhoGAP_BRCC3-like: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of BRCC3-like proteins. This subgroup also contains two groups of closely related proteins, BRCC3 and DEPDC7, which both contain a C-terminal RhoGAP-like domain...; cd04405
T-complex protein 11; pfam05794
T-complex protein 11; pfam05794
Pre-mRNA 3'-end processing (cleavage and polyadenylation) factor [RNA processing and modification]; COG5107
HAT (Half-A-TPR) repeats; smart00386
Suppressor of forked protein (Suf); pfam05843
HAT (Half-A-TPR) repeats; smart00386
Protein kinase domain; pfam00069
Protein Kinases, catalytic domain; cl09925
Protein kinase domain; pfam00069
Protein Kinases, catalytic domain; cl09925
Domain of unknown function (DUF3827); pfam12877
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
F-box-like; pfam12937
SMI1 / KNR4 family (SUKH-1); pfam09346
Protein of unknown function (DUF525); cl01119
F-box-like; pfam12937
SMI1 / KNR4 family (SUKH-1); pfam09346
Protein of unknown function (DUF525); cl01119
The first LIM domain of LMO2 (LIM domain only protein 2); cd09384
The second LIM domain of LMO2 (LIM domain only protein 2); cd09385
The first LIM domain of LMO2 (LIM domain only protein 2); cd09384
The second LIM domain of LMO2 (LIM domain only protein 2); cd09385
The first LIM domain of LMO2 (LIM domain only protein 2); cd09384
The second LIM domain of LMO2 (LIM domain only protein 2); cd09385
Cytoplasmic activation/proliferation-associated protein-1 C term; pfam12287
Cytoplasmic activation/proliferation-associated protein-1 C term; pfam12287
Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]
Domain of unknown function (DUF1726); pfam08351
Helicase; pfam05127
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; cd04301
Possible tRNA binding domain; pfam13725
Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]
Domain of unknown function (DUF1726); pfam08351
Helicase; pfam05127
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; cd04301
Possible tRNA binding domain; pfam13725
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cl00074
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
BTB/POZ domain; pfam00651
Catalase [Inorganic ion transport and metabolism]; COG0753
Clade 3 of the heme-binding enzyme catalase; cd08156
erythroblast transformation specific domain; smart00413
Sterile alpha motif (SAM)/Pointed domain of ESE-2 like ETS transcriptional regulators; cd08538
erythroblast transformation specific domain; smart00413
erythroblast transformation specific domain; smart00413
SAM (Sterile alpha motif ); cl15755
erythroblast transformation specific domain; smart00413
Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators; cd08539
erythroblast transformation specific domain; smart00413
Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators; cd08539
erythroblast transformation specific domain; smart00413
Sterile alpha motif (SAM)/Pointed domain of ESE-3 like ETS transcriptional regulators; cd08539
erythroblast transformation specific domain; smart00413
methylthioribulose-1-phosphate dehydratase; TIGR03328
branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed
Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; cd06849
e3 binding domain; pfam02817
2-oxoacid dehydrogenases acyltransferase (catalytic domain); pfam00198
branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed
Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; cd06849
e3 binding domain; pfam02817
2-oxoacid dehydrogenases acyltransferase (catalytic domain); pfam00198
Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; cd06849
2-oxoacid dehydrogenases acyltransferase (catalytic domain); pfam00198
This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding...; cd03516
This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding...; cd03516
This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding...; cd03516
This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding...; cd03516
This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding...; cd03516
This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding...; cd03516
The link domain is a hyaluronan (HA)-binding domain. It functions to mediate adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It is found in the CD44 receptor and in human TSG-6. TSG-6 is the protein product of the tumor...; cl02612
This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding...; cd03516
Sodium:dicarboxylate symporter family; pfam00375
Na+/H+-dicarboxylate symporters [Energy production and conversion]; COG1301
Sodium:dicarboxylate symporter family; pfam00375
Na+/H+-dicarboxylate symporters [Energy production and conversion]; COG1301
Sodium:dicarboxylate symporter family; pfam00375
Na+/H+-dicarboxylate symporters [Energy production and conversion]; COG1301
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
C-terminal kinase domain of Drosophila Four-jointed (Fj), mouse Fjx1, and related proteins; cd10468
B-box zinc finger; pfam00643
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
COMM_Domain containing protein 9. The COMM Domain is found at the C-terminus of a variety of proteins; presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in protein-protein interactions. Several...; cd04757
COMM_Domain containing protein 9. The COMM Domain is found at the C-terminus of a variety of proteins; presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in protein-protein interactions. Several...; cd04757
HbrB-like; pfam08539
HbrB-like; pfam08539
HbrB-like; pfam08539
HbrB-like; pfam08539
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
TRAF-type zinc finger; pfam02176
TRAF-type zinc finger; pfam02176
Tumor Necrosis Factor Receptor (TNFR)-Associated Factor (TRAF) family, TRAF6 subfamily, TRAF domain, C-terminal MATH subdomain; composed of proteins with similarity to human TRAF6, including the Drosophila protein DTRAF2. TRAF molecules serve as adapter...; cd03776
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
TRAF-type zinc finger; pfam02176
TRAF-type zinc finger; pfam02176
Tumor Necrosis Factor Receptor (TNFR)-Associated Factor (TRAF) family, TRAF6 subfamily, TRAF domain, C-terminal MATH subdomain; composed of proteins with similarity to human TRAF6, including the Drosophila protein DTRAF2. TRAF molecules serve as adapter...; cd03776
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Recombination-activating protein 1 zinc-finger domain; pfam10426
Recombination-activation protein 1 (RAG1); pfam12940
Recombination activating protein 2; pfam03089
RAG2 PHD domain; pfam13341
Recombination activating protein 2; pfam03089
RAG2 PHD domain; pfam13341
Recombination activating protein 2; pfam03089
RAG2 PHD domain; pfam13341
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Apoptosis inhibitory protein 5 (API5); pfam05918
HEAT repeats; pfam13646
Apoptosis inhibitory protein 5 (API5); pfam05918
HEAT repeats; pfam13646
Apoptosis inhibitory protein 5 (API5); pfam05918
Apoptosis inhibitory protein 5 (API5); pfam05918
Apoptosis inhibitory protein 5 (API5); pfam05918
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Short-chain dehydrogenases of various substrate specificities [General function prediction only]; COG0300
17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs; cd05356
2OG-Fe(II) oxygenase superfamily; pfam13532
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; cd00609
Aminotransferase class I and II; pfam00155
Aminotransferase class I and II; pfam00155
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; cd00609
Aminotransferase class I and II; pfam00155
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; cd00609
Exostosin family; pfam03016
Glycosyl transferase family 64 domain; pfam09258
Exostosin family; pfam03016
Glycosyl transferase family 64 domain; pfam09258
Exostosin family; pfam03016
Glycosyl transferase family 64 domain; pfam09258
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
OAR domain; pfam03826
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment...; cd03160
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment...; cd03160
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), uroplakin_I_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment...; cd03156
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
C2 domain; cd08677
C2 domain second repeat present in Synaptotagmin 13; cd08407
C2 domain; cl14603
C2 domain second repeat present in Synaptotagmin 13; cd08407
Sulfotransferase domain; pfam00685
Nucleotide-sugar transporter [Carbohydrate transport and metabolism / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; COG5070
EamA-like transporter family; cl01037
Nucleotide-sugar transporter [Carbohydrate transport and metabolism / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; COG5070
EamA-like transporter family; cl01037
Nucleotide-sugar transporter [Carbohydrate transport and metabolism / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; COG5070
EamA-like transporter family; cl01037
Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; COG0415
DNA photolyase; pfam00875
FAD binding domain of DNA photolyase; pfam03441
Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; COG0415
DNA photolyase; pfam00875
FAD binding domain of DNA photolyase; pfam03441
Src homology 3 domain of JNK-interacting protein 1; cd11943
Pleckstrin homology-like domain; cl00273
Peroxisomal membrane protein (Pex16); pfam08610
Peroxisomal membrane protein (Pex16); pfam08610
LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis; cd06431
Glycosyl transferase family 8; pfam01501
Glycosyl-transferase for dystroglycan; pfam13896
Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]; COG5034
PHD-finger; pfam00628
PHD-finger; pfam00628
basic region leucin zipper; smart00338
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; COG1597
Diacylglycerol kinase catalytic domain (presumed); smart00046
Diacylglycerol kinase accessory domain (presumed); smart00045
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; COG1597
Diacylglycerol kinase catalytic domain (presumed); smart00046
Diacylglycerol kinase accessory domain (presumed); smart00045
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; COG1597
Diacylglycerol kinase catalytic domain (presumed); smart00046
Diacylglycerol kinase accessory domain (presumed); smart00045
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; COG1597
Diacylglycerol kinase catalytic domain (presumed); smart00046
Diacylglycerol kinase accessory domain (presumed); smart00045
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; COG1597
Diacylglycerol kinase catalytic domain (presumed); smart00046
Diacylglycerol kinase accessory domain (presumed); smart00045
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; COG1597
Diacylglycerol kinase catalytic domain (presumed); smart00046
Diacylglycerol kinase accessory domain (presumed); smart00045
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; COG1597
Diacylglycerol kinase catalytic domain (presumed); smart00046
Diacylglycerol kinase accessory domain (presumed); smart00045
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Pleiotrophin / midkine family; smart00193
Pleiotrophin / midkine family; smart00193
Pleiotrophin / midkine family; smart00193
Pleiotrophin / midkine family; smart00193
Pleiotrophin / midkine family; smart00193
PTN/MK heparin-binding protein family, N-terminal domain; cl02505
7 transmembrane receptor (rhodopsin family); pfam00001
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
DDE superfamily endonuclease; pfam13359
Autophagy-related protein 13; pfam10033
Autophagy-related protein 13; pfam10033
Autophagy-related protein 13; pfam10033
Autophagy-related protein 13; pfam10033
Autophagy-related protein 13; pfam10033
Autophagy-related protein 13; pfam10033
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
RhoGAP-p50rhoGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of p50RhoGAP-like proteins; p50RhoGAP, also known as RhoGAP-1, contains a C-terminal RhoGAP domain and an N-terminal Sec14 domain which binds phosphatidylinositol...; cd04404
GTPase-activator protein for Rho-like GTPases; smart00324
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Domain containing Gla (gamma-carboxyglutamate) residues; smart00069
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and...; cd00108
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and...; cd00108
Thrombin light chain; pfam09396
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
CLASP N terminal; pfam12348
CLASP N terminal; pfam12348
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cl00104
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Uncharacterized conserved protein [Function unknown]
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Putative GTPase activating protein for Arf; pfam01412
Putative GTPase activating protein for Arf; pfam01412
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 3 (PACSIN3); cd07681
Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 3 (PACSIN3); cd11997
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 3 (PACSIN3); cd07681
Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 3 (PACSIN3); cd11997
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 3 (PACSIN3); cd07681
Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 3 (PACSIN3); cd11997
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; cd07061
Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; cd07061
DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers; cd07160
The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors; cd06954
DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers; cd07160
The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors; cd06954
DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers; cd07160
The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors; cd06954
DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers; cd07160
The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators; cl11397
DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers; cd07160
The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors; cd06954
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; smart00799
Domain always found downstream of DENN domain, found in a variety of signalling proteins; smart00801
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; smart00799
Domain always found downstream of DENN domain, found in a variety of signalling proteins; smart00801
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; smart00799
Domain always found downstream of DENN domain, found in a variety of signalling proteins; smart00801
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; smart00799
Domain always found downstream of DENN domain, found in a variety of signalling proteins; smart00801
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; smart00799
Domain always found downstream of DENN domain, found in a variety of signalling proteins; smart00801
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; smart00799
Domain always found downstream of DENN domain, found in a variety of signalling proteins; smart00801
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; smart00799
Domain always found downstream of DENN domain, found in a variety of signalling proteins; smart00801
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; smart00799
Domain always found downstream of DENN domain, found in a variety of signalling proteins; smart00801
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; smart00799
Domain always found downstream of DENN domain, found in a variety of signalling proteins; smart00801
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; smart00799
Domain always found downstream of DENN domain, found in a variety of signalling proteins; smart00801
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C); cd05894
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin (Ig)-like domain of titin and similar proteins; cd05748
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Ets-domain; pfam00178
Ets-domain; pfam00178
ZIP Zinc transporter; pfam02535
Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]
ZIP Zinc transporter; pfam02535
Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones]; COG1222
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Rapsyn N-terminal myristoylation and linker region; pfam10579
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Rapsyn N-terminal myristoylation and linker region; pfam10579
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cl00053
Broad-Complex, Tramtrack and Bric a brac; smart00225
kelch-like protein; Provisional
BTB And C-terminal Kelch; smart00875
Galactose oxidase, central domain; pfam13415
Broad-Complex, Tramtrack and Bric a brac; smart00225
kelch-like protein; Provisional
BTB And C-terminal Kelch; smart00875
Galactose oxidase, central domain; pfam13415
NADH dehydrogenase subunit C; Provisional
NADH (or F420H2) dehydrogenase, subunit C; TIGR01961
C1q domain; pfam00386
C1q domain; pfam00386
Mitochondrial carrier protein; pfam00153
Putative binding domain; pfam13900
Peptidase M14-like domain of ATP/GTP binding protein AGBL-2 and AGBL-3, and related proteins; cd06907
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Nucleoporin Nup120/160; pfam11715
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; smart00060
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
Domain in SPla and the RYanodine Receptor; smart00449
Zinc peptidases M18, M20, M28, and M42; cl14876
PA_GCPII_like: Protease-associated domain containing protein, glutamate carboxypeptidase II (GCPII)-like. This group contains various PA domain-containing proteins similar to GCPII including, GCPIII (NAALADase2) and NAALADase L. These proteins belong to...; cd02121
Predicted aminopeptidases [General function prediction only]; COG2234
M28 Zn-peptidase prostate-specific membrane antigen; cd08022
Transferrin receptor-like dimerisation domain; pfam04253
Zinc peptidases M18, M20, M28, and M42; cl14876
PA_GCPII_like: Protease-associated domain containing protein, glutamate carboxypeptidase II (GCPII)-like. This group contains various PA domain-containing proteins similar to GCPII including, GCPIII (NAALADase2) and NAALADase L. These proteins belong to...; cd02121
Predicted aminopeptidases [General function prediction only]; COG2234
M28 Zn-peptidase prostate-specific membrane antigen; cd08022
Transferrin receptor-like dimerisation domain; pfam04253
Zinc peptidases M18, M20, M28, and M42; cl14876
PA_GCPII_like: Protease-associated domain containing protein, glutamate carboxypeptidase II (GCPII)-like. This group contains various PA domain-containing proteins similar to GCPII including, GCPIII (NAALADase2) and NAALADase L. These proteins belong to...; cd02121
Predicted aminopeptidases [General function prediction only]; COG2234
M28 Zn-peptidase prostate-specific membrane antigen; cd08022
Transferrin receptor-like dimerisation domain; pfam04253
Zinc peptidases M18, M20, M28, and M42; cl14876
PA_GCPII_like: Protease-associated domain containing protein, glutamate carboxypeptidase II (GCPII)-like. This group contains various PA domain-containing proteins similar to GCPII including, GCPIII (NAALADase2) and NAALADase L. These proteins belong to...; cd02121
Predicted aminopeptidases [General function prediction only]; COG2234
M28 Zn-peptidase prostate-specific membrane antigen; cd08022
Transferrin receptor-like dimerisation domain; pfam04253
M28 Zn-peptidase prostate-specific membrane antigen; cd08022
Predicted aminopeptidases [General function prediction only]; COG2234
Transferrin receptor-like dimerisation domain; pfam04253
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Domain in SPla and the RYanodine Receptor; smart00449
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Leucine rich repeat N-terminal domain; smart00013
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
7 transmembrane receptor (rhodopsin family); pfam00001
Nucleosome-binding factor SPN, POB3 subunit [Transcription / DNA replication, recombination, and repair / Chromatin structure and dynamics]; COG5165
Structure-specific recognition protein (SSRP1); pfam03531
Histone chaperone Rttp106-like; pfam08512
Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]; COG5648
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
ATP P2X receptor; pfam00864
C-type lectin-like domain (CTLD) of the type found in the human proteins, eosinophil major basic protein (EMBP) and prepro major basic protein homolog (MBPH); cd03598
C-type lectin-like domain (CTLD) of the type found in the human proteins, eosinophil major basic protein (EMBP) and prepro major basic protein homolog (MBPH); cd03598
C-type lectin-like domain (CTLD) of the type found in the human proteins, eosinophil major basic protein (EMBP) and prepro major basic protein homolog (MBPH); cd03598
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Tim10/DDP family zinc finger; pfam02953
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
C1 inhibitor (C1-Inh) is a protease inhibitor of the serpin family. It plays a pivotal role in regulating the activation of the classical complement pathway and of the contact system, via regulating bradykinin formation, inhibiting factor XII and...; cd02050
C1 inhibitor (C1-Inh) is a protease inhibitor of the serpin family. It plays a pivotal role in regulating the activation of the classical complement pathway and of the contact system, via regulating bradykinin formation, inhibiting factor XII and...; cd02050
Yippee putative zinc-binding protein; pfam03226
Predicted GTPase subunit of the pre-mRNA cleavage complex [Translation, ribosomal structure and biogenesis]; COG5623
Molybdopterin guanine dinucleotide synthesis protein B; pfam03205
Pre-mRNA cleavage complex II protein Clp1; pfam06807
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Pre-mRNA cleavage complex II protein Clp1; pfam06807
DHHC palmitoyltransferase; pfam01529
Mediator of RNA pol II transcription subunit 19; pfam10278
TMX2 family; composed of proteins similar to human TMX2, a 372-amino acid TRX-related transmembrane protein, identified and characterized through the cloning of its cDNA from a human fetal library. It contains a TRX domain but the redox active CXXC motif...; cd02962
TMX2 family; composed of proteins similar to human TMX2, a 372-amino acid TRX-related transmembrane protein, identified and characterized through the cloning of its cDNA from a human fetal library. It contains a TRX domain but the redox active CXXC motif...; cd02962
selT/selW/selH selenoprotein domain; TIGR02174
BTB/POZ domain; pfam00651
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
The first LIM domain of Leupaxin; cd09406
The second LIM domain of Leupaxin; cd09408
The third LIM domain of Leupaxin; cd09410
The fourth LIM domain of the Paxillin-like protein family; cd09339
The first LIM domain of Leupaxin; cd09406
The second LIM domain of Leupaxin; cd09408
The third LIM domain of Leupaxin; cd09410
The fourth LIM domain of the Paxillin-like protein family; cd09339
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Ciliary neurotrophic factor; pfam01110
Aralkyl acyl-CoA:amino acid N-acyltransferase; pfam06021
Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region; pfam08444
Aralkyl acyl-CoA:amino acid N-acyltransferase; pfam06021
Aralkyl acyl-CoA:amino acid N-acyltransferase; pfam06021
Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region; pfam08444
Aralkyl acyl-CoA:amino acid N-acyltransferase; pfam06021
Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region; pfam08444
Aralkyl acyl-CoA:amino acid N-acyltransferase; pfam06021
Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region; pfam08444
Aralkyl acyl-CoA:amino acid N-acyltransferase; pfam06021
Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region; pfam08444
Trypsin-like peptidase domain; pfam13365
Trypsin-like peptidase domain; pfam13365
Trypsin-like peptidase domain; pfam13365
Trypsin-like peptidase domain; pfam13365
Trypsin-like peptidase domain; pfam13365
Trypsin-like peptidase domain; pfam13365
Trypsin-like peptidase domain; pfam13365
Trypsin-like peptidase domain; pfam13365
Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis; smart00678
WWE domain; pfam02825
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Domain found at the C-terminus of deltex-like; cd09633
MAC/Perforin domain; pfam01823
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Oxysterol binding protein (OSBP) Pleckstrin homology (PH) domain; cd01246
Oxysterol-binding protein; pfam01237
Topoisomerase II-associated protein PAT1; pfam09770
Topoisomerase II-associated protein PAT1; pfam09770
Olfactory receptor; pfam13853
Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may...; cd00179
Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in...; cd00193
Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may...; cd00179
Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in...; cd00193
Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; cd01433
Eukaryotic cobalamin-binding protein; pfam01122
Eukaryotic cobalamin-binding protein; pfam01122
Zona pellucida-like domain; cl02523
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
CD20-like family; pfam04103
7 transmembrane receptor (rhodopsin family); pfam00001
P or trefoil or TFF domain; Trefoil factor family domain peptides are mucin-associated molecules, largely found in epithelia of gastrointestinal tissues. Function is not known but it was originally identified from mucosal tissues, where it may have a...; cl00103
Zona pellucida (ZP) domain; smart00241
Modified RING finger domain; smart00504
Prp19/Pso4-like; pfam08606
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cl11420
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor cysteine-rich domain; pfam00530
Modifier of rudimentary (Mod(r)) protein; pfam07200
A1 Propeptide; pfam07966
Pepsin A, aspartic protease produced in gastric mucosa of mammals; cd05478
Eukaryotic aspartyl protease; pfam00026
A1 Propeptide; pfam07966
Pepsin A, aspartic protease produced in gastric mucosa of mammals; cd05478
Eukaryotic aspartyl protease; pfam00026
A1 Propeptide; pfam07966
Pepsin A, aspartic protease produced in gastric mucosa of mammals; cd05478
Eukaryotic aspartyl protease; pfam00026
Calcium-binding EGF-like domain; smart00179
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain; smart00179
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
Mono-functional DNA-alkylating methyl methanesulfonate N-term; pfam10433
CPSF A subunit region; pfam03178
dihydroxyacetone kinase, ATP-dependent; TIGR02361
dihydroxyacetone kinase subunit DhaK; Provisional; cl10557
DAK2 domain; pfam02734
Vertebrate cytochrome b(561), CYBASC3 gene product; cd08762
Vertebrate cytochrome b(561), CYBASC3 gene product; cd08762
Vertebrate cytochrome b(561), CYBASC3 gene product; cd08762
Predicted membrane protein; pfam09799
Predicted membrane protein; pfam09799
Predicted membrane protein; pfam09799
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Flavinator of succinate dehydrogenase; pfam03937
Leucine-rich repeat (LRR) protein [Function unknown]
C2A domain first repeat present in Synaptotagmin 7; cd08386
C2 domain second repeat present in Synaptotagmin 7; cd08405
C2A domain first repeat present in Synaptotagmin 7; cd08386
C2 domain second repeat present in Synaptotagmin 7; cd08405
Lipase (class 3).  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is 'interfacial activation,' the process of...; cd00519
NDT80 / PhoG like DNA-binding family; pfam05224
Chaperone of endosialidase; pfam13884
Myelin gene regulatory factor -C-terminal domain 1; pfam13887
Myelin gene regulatory factor C-terminal domain 2; pfam13888
NDT80 / PhoG like DNA-binding family; pfam05224
Chaperone of endosialidase; pfam13884
Myelin gene regulatory factor -C-terminal domain 1; pfam13887
Myelin gene regulatory factor C-terminal domain 2; pfam13888
Uncharacterized protein family (UPF0197); pfam05251
flap endonuclease-1; Provisional
PIN domain of Flap Endonuclease-1, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs; cd09867
H3TH domain of Flap Endonuclease-1, a structure-specific, divalent-metal-ion dependent, 5' nuclease: Eukaryotic homologs; cd09907
PIN (PilT N terminus) domain: Superfamily; cl14812
delta6-acyl-lipid desaturase-like protein; Provisional
Cytochrome b5-like Heme/Steroid binding domain; pfam00173
The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; cd03506
delta6-acyl-lipid desaturase-like protein; Provisional
Cytochrome b5-like Heme/Steroid binding domain; pfam00173
The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; cd03506
delta6-acyl-lipid desaturase-like protein; Provisional
Cytochrome b5-like Heme/Steroid binding domain; pfam00173
The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; cd03506
GDP/GTP exchange factor Sec2p; pfam06428
Bestrophin, RFP-TM, chloride channel; pfam01062
Bestrophin, RFP-TM, chloride channel; pfam01062
eukaryotic ferritins; cd01056
Ferritin-like domain; pfam00210
Chromosome passenger complex (CPC) protein INCENP N terminal; pfam12178
Inner centromere protein, ARK binding region; pfam03941
Chromosome passenger complex (CPC) protein INCENP N terminal; pfam12178
Inner centromere protein, ARK binding region; pfam03941
Secretoglobins are relatively small, secreted, disulphide-bridged dimeric proteins with encoding genes sharing substantial sequence similarity. Their family subunits may be grouped into five subfamilies, A-E. Uteroglobin (subfamily A), which is identical...; cd00633
Secretoglobins are relatively small, secreted, disulphide-bridged dimeric proteins with encoding genes sharing substantial sequence similarity. Their family subunits may be grouped into five subfamilies, A-E. Uteroglobin (subfamily A), which is identical...; cd00633
Secretoglobins are relatively small, secreted, disulphide-bridged dimeric proteins with encoding genes sharing substantial sequence similarity. Their family subunits may be grouped into five subfamilies, A-E. Uteroglobin (subfamily A), which is identical...; cd00633
Secretoglobins are relatively small, secreted, disulphide-bridged dimeric proteins with encoding genes sharing substantial sequence similarity. Their family subunits may be grouped into five subfamilies, A-E. Uteroglobin (subfamily A), which is identical...; cd00633
Secretoglobins are relatively small, secreted, disulphide-bridged dimeric proteins with encoding genes sharing substantial sequence similarity. Their family subunits may be grouped into five subfamilies, A-E. Uteroglobin (subfamily A), which is identical...; cd00633
ASRGL1_like domains, a subfamily of the L-Asparaginase type 2-like enzymes. The wider family includes Glycosylasparaginase, Taspase 1 and L-Asparaginase type 2 enzymes. The proenzymes undergo autoproteolytic cleavage before a threonine to generate alpha...; cd04702
ASRGL1_like domains, a subfamily of the L-Asparaginase type 2-like enzymes. The wider family includes Glycosylasparaginase, Taspase 1 and L-Asparaginase type 2 enzymes. The proenzymes undergo autoproteolytic cleavage before a threonine to generate alpha...; cd04702
Secretoglobins are relatively small, secreted, disulphide-bridged dimeric proteins with encoding genes sharing substantial sequence similarity. Their family subunits may be grouped into five subfamilies, A-E. Uteroglobin (subfamily A), which is identical...; cd00633
PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; cd00988
Uncharacterized protein conserved in bacteria [Function unknown]
Uncharacterized protein conserved in bacteria [Function unknown]
Uncharacterized protein conserved in bacteria [Function unknown]
GST_N family, Gamma subunit of Elongation Factor 1B (EFB1gamma) subfamily; EF1Bgamma is part of the eukaryotic translation elongation factor-1 (EF1) complex which plays a central role in the elongation cycle during protein biosynthesis. EF1 consists of...; cd03044
Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; COG0625
Glutathione S-transferase C-terminal-like, alpha helical domain of the Gamma subunit of Elongation Factor 1B and similar proteins; cd03181
Elongation factor 1 gamma, conserved domain; pfam00647
Zinc-finger of C2H2 type; pfam12874
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases; cd05402
Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases; cd05402
Cid1 family poly A polymerase; pfam03828
BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH...; cd04709
ELM2 domain; pfam01448
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
Myb-Like Dna-Binding Domain of MTA3 and related proteins; cd11661
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C; cd00202
HELP motif; pfam03451
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Tetraspanin, extracellular domain or large extracellular loop (LEL), peripherin_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment...; cd03162
Tetraspanin family; pfam00335
Beta1,3-glucuronyltransferase I (GlcAT-I) is involved in the initial steps of proteoglycan synthesis; cd00218
Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]
Galactose mutarotase-like; pfam13802
This family includes the closely related glycosyl hydrolase family 31 (GH31) isozymes, neutral alpha-glucosidase C (GANC) and the alpha subunit of heterodimeric neutral alpha-glucosidase AB (GANAB). Initially distinguished on the basis of differences in...; cd06603
Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]
Galactose mutarotase-like; pfam13802
This family includes the closely related glycosyl hydrolase family 31 (GH31) isozymes, neutral alpha-glucosidase C (GANC) and the alpha subunit of heterodimeric neutral alpha-glucosidase AB (GANAB). Initially distinguished on the basis of differences in...; cd06603
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Methyltransferase domain; pfam13847
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
SAKS1-like UBX domain; cd01772
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Putative adipose-regulatory protein (Seipin); pfam06775
Putative adipose-regulatory protein (Seipin); pfam06775
Protein phosphatase inhibitor 1/DARPP-32; pfam05395
Putative adipose-regulatory protein (Seipin); pfam06775
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors; cd00068
Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation; smart00513
SPRY domain; pfam00622
AAA domain; pfam13671
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
DNA-directed RNA polymerase II subunit 7; Provisional
RNAP_II_Rpb7_N: Rpb7, N-terminal ribonucleoprotein (RNP) domain. Rpb7 is a subunit of eukaryotic RNA polymerase (RNAP) II that is homologous to Rpc25 of RNAP III, RpoE of archaeal RNAP, and Rpa43 of eukaryotic RNAP I. Rpb7 heterodimerizes with Rpb4 and...; cd04329
S1_RNAPII_Rpb7: Eukaryotic RNA polymerase II (RNAPII) Rpb7 subunit C-terminal S1 domain. RNAPII is composed of 12 subunits (Rpb1-12). Rpb4 and Rpb7 form a heterodimer that associate with the RNAPII core. Rpb7 is a homolog of the Rpc25 of RNA polymerase...; cd04462
TATA Binding Protein (TBP) Associated Factor 6 (TAF6) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex; cd08050
Tap, RNA-binding; pfam09162
Leucine Rich repeats (2 copies); pfam12799
Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many...; cd00780
TAP C-terminal domain; pfam03943
Tap, RNA-binding; pfam09162
Leucine Rich repeats (2 copies); pfam12799
Syntaxin; pfam00804
Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in...; cd00193
Syntaxin; pfam00804
Helical region found in SNAREs; smart00397
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Alpha amylase catalytic domain found in solute carrier family 3 member 2 proteins; cd11345
Glycosidases [Carbohydrate transport and metabolism]; COG0366
Alpha amylase catalytic domain found in solute carrier family 3 member 2 proteins; cd11345
Glycosidases [Carbohydrate transport and metabolism]; COG0366
Alpha amylase catalytic domain found in solute carrier family 3 member 2 proteins; cd11345
Glycosidases [Carbohydrate transport and metabolism]; COG0366
Alpha amylase catalytic domain found in solute carrier family 3 member 2 proteins; cd11345
Glycosidases [Carbohydrate transport and metabolism]; COG0366
7 transmembrane receptor (rhodopsin family); pfam00001
cation transport protein; TIGR00898
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
cation transport protein; TIGR00898
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
cation transport protein; TIGR00898
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
cation transport protein; TIGR00898
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
cation transport protein; TIGR00898
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cl11420
cation transport protein; TIGR00898
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cl11420
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Sugar (and other) transporter; pfam00083
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
cation transport protein; TIGR00898
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
cation transport protein; TIGR00898
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
cation transport protein; TIGR00898
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
cation transport protein; TIGR00898
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Lecithin retinol acyltransferase; pfam04970
Lecithin retinol acyltransferase; pfam04970
Lecithin retinol acyltransferase; pfam04970
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galactoside-binding lectin; smart00908
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galactoside-binding lectin; smart00908
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galactoside-binding lectin; smart00908
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galactoside-binding lectin; smart00908
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galactoside-binding lectin; smart00908
Lecithin retinol acyltransferase; pfam04970
Lecithin retinol acyltransferase; pfam04970
Lecithin retinol acyltransferase; pfam04970
Lecithin retinol acyltransferase; pfam04970
Guanylate-binding protein (GBP) family (N-terminal domain); cd01851
Reticulon; pfam02453
Reticulon; pfam02453
Reticulon; pfam02453
Reticulon; pfam02453
Reticulon; pfam02453
Reticulon; pfam02453
Reticulon; pfam02453
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Kinase associated domain 1; pfam02149
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Kinase associated domain 1; pfam02149
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Kinase associated domain 1; pfam02149
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Kinase associated domain 1; pfam02149
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Kinase associated domain 1; pfam02149
ELM2 domain; pfam01448
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cl15779
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
Acetyltransferase (GNAT) family; pfam00583
Cytochrome oxidase c subunit VIII.  Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; cd00930
Peptidase C65 Otubain; pfam10275
Macro domain, Appr-1'-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose...; cd02908
Leucine rich repeat N-terminal domain; smart00013
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Fibronectin type 3 domain; smart00060
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Heat shock chaperonin-binding motif; smart00727
Band 4.1 homologues; smart00295
FERM central domain; pfam00373
Pleckstrin homology-like domain; cl00273
FERM central domain; pfam00373
Band 4.1 homologues; smart00295
FERM central domain; pfam00373
Pleckstrin homology-like domain; cl00273
FERM central domain; pfam00373
RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; COG1859
RNA 2'-phosphotransferase, Tpt1 / KptA family; pfam01885
RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; COG1859
RNA 2'-phosphotransferase, Tpt1 / KptA family; pfam01885
RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; COG1859
RNA 2'-phosphotransferase, Tpt1 / KptA family; pfam01885
RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; COG1859
RNA 2'-phosphotransferase, Tpt1 / KptA family; pfam01885
RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; COG1859
RNA 2'-phosphotransferase, Tpt1 / KptA family; pfam01885
RNA 2'-phosphotransferase, Tpt1 / KptA family; pfam01885
RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; COG1859
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]; COG0484
Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family domain; PDGF is a potent activator for cells of mesenchymal origin; PDGF-A and PDGF-B form AA and BB homodimers and an AB heterodimer; VEGF is a potent mitogen in embryonic and...; cd00135
Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family domain; PDGF is a potent activator for cells of mesenchymal origin; PDGF-A and PDGF-B form AA and BB homodimers and an AB heterodimer; VEGF is a potent mitogen in embryonic and...; cd00135
FKBP-type peptidyl-prolyl cis-trans isomerase; pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; COG0545
FKBP-type peptidyl-prolyl cis-trans isomerase; pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; COG0545
FKBP-type peptidyl-prolyl cis-trans isomerase; pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; COG0545
PKC-activated protein phosphatase-1 inhibitor; pfam05361
Phospholipase C (PLC) pleckstrin homology (PH) domain; cd01248
Phosphoinositide-specific phospholipase C, efhand-like; pfam09279
Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta; cd08591
Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; cl14615
C2 domain present in Phosphoinositide-specific phospholipases C (PLC); cd00275
Protein of unknown function (DUF1154); pfam06631
PLC-beta C terminal; pfam08703
Pleckstrin homology-like domain; cl00273
Phosphoinositide-specific phospholipase C, efhand-like; pfam09279
Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta; cd08591
Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; cl14615
C2 domain present in Phosphoinositide-specific phospholipases C (PLC); cd00275
Protein of unknown function (DUF1154); pfam06631
PLC-beta C terminal; pfam08703
Pro-apoptotic Bcl-2 protein, BAD; pfam10514
Pro-apoptotic Bcl-2 protein, BAD; pfam10514
Ion channel; pfam07885
Ion channel; pfam07885
DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers; cd07170
The ligand binding domain of estrogen receptor-related nuclear receptors; cd06946
Trm112p-like protein; cl01066
cytoplasmic/peroxisomal protein
Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5...; cd03013
Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; COG0450
cytoplasmic/peroxisomal protein
Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5...; cd03013
cytoplasmic/peroxisomal protein
Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; cl00388
large tegument protein UL36; Provisional
chromosome segregation protein SMC, common bacterial type; TIGR02168
N-terminal catalytic domain of the Protein Serine/Threonine Kinase, Mitogen and stress-activated kinase 2; cd05614
Serine/Threonine protein kinases, catalytic domain; smart00220
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
N-terminal catalytic domain of the Protein Serine/Threonine Kinase, Mitogen and stress-activated kinase 2; cd05614
Serine/Threonine protein kinases, catalytic domain; smart00220
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
cation transport protein; TIGR00898
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
cation transport protein; TIGR00898
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; cl10013
This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; cd04300
glycogen/starch/alpha-glucan phosphorylases; TIGR02093
This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; cd04300
glycogen/starch/alpha-glucan phosphorylases; TIGR02093
Splicing factor (branch point binding protein) [RNA processing and modification]; COG5176
Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1...; cd02395
Splicing factor (branch point binding protein) [RNA processing and modification]; COG5176
Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1...; cd02395
Splicing factor (branch point binding protein) [RNA processing and modification]; COG5176
Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1...; cd02395
Splicing factor (branch point binding protein) [RNA processing and modification]; COG5176
Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1...; cd02395
Splicing factor (branch point binding protein) [RNA processing and modification]; COG5176
Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1...; cd02395
Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1...; cd02395
Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase-like Protein Serine/Threonine Kinases; cd06613
Serine/Threonine protein kinases, catalytic domain; smart00220
Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2; smart00036
Menin; pfam05053
Menin; pfam05053
Menin; pfam05053
Menin; pfam05053
Menin; pfam05053
Menin; pfam05053
Menin; pfam05053
Catalytic domain of Myotonic Dystrophy protein kinase-like Protein Serine/Threonine Kinases; cd05597
Serine/Threonine protein kinases, catalytic domain; smart00220
DMPK coiled coil domain like; pfam08826
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Pleckstrin homology-like domain; cl00273
CNH domain; pfam00780
Eps15 homology domain (EHD), C-terminal domain; cd09913
Dynamin family; pfam00350
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
N-terminal region of Chorein, a TM vesicle-mediated sorter; pfam12624
ATG C terminal domain; pfam09333
Protein phosphatase 2A regulatory B subunit (B56 family); pfam01603
basic region leucin zipper; smart00338
Arf-like 2 (Arl2) GTPase; cd04154
GTPase SAR1 and related small G proteins [General function prediction only]
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
GTPase SAR1 and related small G proteins [General function prediction only]
The phosphoinositide binding Phox Homology domain of Sorting Nexin 15; cd07288
Microtubule Interacting and Trafficking molecule domain; smart00745
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This MIT domain sub-family is found in sorting nexin 15 and related proteins. The molecular function of the MIT domain is unclear; cd02677
The Phox Homology domain, a phosphoinositide binding module; cl02563
Microtubule Interacting and Trafficking molecule domain; smart00745
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This MIT domain sub-family is found in sorting nexin 15 and related proteins. The molecular function of the MIT domain is unclear; cd02677
SAC3/GANP/Nin1/mts3/eIF-3 p25 family; pfam03399
Zinc peptidases M18, M20, M28, and M42; cl14876
PA_GCPII_like: Protease-associated domain containing protein, glutamate carboxypeptidase II (GCPII)-like. This group contains various PA domain-containing proteins similar to GCPII including, GCPIII (NAALADase2) and NAALADase L. These proteins belong to...; cd02121
Predicted aminopeptidases [General function prediction only]; COG2234
M28 Zn-peptidase prostate-specific membrane antigen; cd08022
Transferrin receptor-like dimerisation domain; pfam04253
Sororin protein; pfam09666
Vps51/Vps67; pfam08700
Phospholipid methyltransferase; cl00763
HIT zinc finger; pfam04438
Fubi ubiquitin-like protein; cd01793
Ubiquitin homologues; smart00213
Ribosomal protein S30; pfam04758
Mitochondrial large subunit ribosomal protein (Img2); pfam05046
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Cell cycle regulatory protein; pfam11357
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction; cd00044
Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are...; cd00214
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction; cd00044
Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are...; cd00214
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction; cd00044
Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are...; cd00214
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
DNA polymerase alpha subunit B N-terminal; pfam08418
DNA polymerase alpha/epsilon subunit B; pfam04042
P21-Rho-binding domain; pfam00786
N-terminal domain of DPF2/REQ; pfam14051
PHD-finger; pfam00628
PHD-finger; pfam00628
Helix-turn-helix domains; cl00088
Tc5 transposase DNA-binding domain; pfam03221
Integrase core domain; cl01316
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Band 4.1 homologues; smart00295
FERM central domain; pfam00373
Protein Kinases, catalytic domain; cl09925
Protein Kinases, catalytic domain; cl09925
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Calcium-binding EGF-like domain; smart00179
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Calcium-binding EGF-like domain; smart00179
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27); pfam06677
N-terminal C2 in EEIG1 and EHBP1 proteins; pfam10358
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Protein of unknown function (DUF3585); pfam12130
Ion channel; pfam07885
Ion channel; pfam07885
Ion channel; pfam07885
Ion channel; pfam07885
Src Homology 3 domain superfamily; cl17036
Protein kinase; unclassified specificity; smart00221
Catalytic domain of Protein Tyrosine Kinases; cd00192
Pecanex protein (C-terminus); pfam05041
Rap/ran-GAP; pfam02145
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Nnf1; pfam03980
Rap/ran-GAP; pfam02145
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Nnf1; pfam03980
N-terminal sub-domain of the Rel homology domain (RHD) of RelA; cd07885
IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to...; cd01177
N-terminal sub-domain of the Rel homology domain (RHD) of RelA; cd07885
IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to...; cd01177
N-terminal sub-domain of the Rel homology domain (RHD) of RelA; cd07885
IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to...; cd01177
N-terminal sub-domain of the Rel homology domain (RHD) of RelA; cd07885
IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to...; cd01177
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
probable histone acetyltransferase MYST; Provisional
MOZ/SAS family; pfam01853
Histone acetyltransferase (MYST family) [Chromatin structure and dynamics]; COG5027
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
MOZ/SAS family; pfam01853
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
probable histone acetyltransferase MYST; Provisional
MOZ/SAS family; pfam01853
Histone acetyltransferase (MYST family) [Chromatin structure and dynamics]; COG5027
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
MOZ/SAS family; pfam01853
Ribonuclease H2-C is a subunit of the eukaryotic RNase H complex which cleaves RNA-DNA hybrids; cd09271
Zinc-finger double domain; pfam13465
The phosphoinositide binding Phox Homology domain of Sorting Nexins 5 and 6; cd06892
The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexins 5 and 6; cd07621
Cofilin, Destrin, and related actin depolymerizing factors; cd11286
ERCC4-type nuclease [DNA replication, recombination, and repair]; COG1948
ERCC4 domain; smart00891
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Complement Clr-like EGF-like; pfam12662
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
cathepsin L protease; Provisional
Cathepsin propeptide inhibitor domain (I29); smart00848
Peptidase C1A subfamily (MEROPS database nomenclature); composed of cysteine peptidases (CPs) similar to papain, including the mammalian CPs (cathepsins B, C, F, H, L, K, O, S, V, X and W). Papain is an endopeptidase with specific substrate preferences; cd02248
Acidic fibroblast growth factor binding (FIBP); pfam05427
Acidic fibroblast growth factor binding (FIBP); pfam05427
Uncharacterized conserved proteins (DUF2216); pfam10226
basic region leucin zipper; smart00338
Domain of unknown function (DUF1917); pfam08939
Domain of unknown function (DUF1917); pfam08939
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cl00074
SART-1 family; pfam03343
SART-1 family; pfam03343
S1_eIF1AD_like: eukaryotic translation initiation factor 1A domain containing protein (eIF1AD)-like, S1-like RNA-binding domain. eIF1AD is also known as MGC11102 protein. Little is known about the function of eIF1AD. S1-like RNA-binding domains are found...; cd05792
S1_eIF1AD_like: eukaryotic translation initiation factor 1A domain containing protein (eIF1AD)-like, S1-like RNA-binding domain. eIF1AD is also known as MGC11102 protein. Little is known about the function of eIF1AD. S1-like RNA-binding domains are found...; cd05792
S1_eIF1AD_like: eukaryotic translation initiation factor 1A domain containing protein (eIF1AD)-like, S1-like RNA-binding domain. eIF1AD is also known as MGC11102 protein. Little is known about the function of eIF1AD. S1-like RNA-binding domains are found...; cd05792
S1_eIF1AD_like: eukaryotic translation initiation factor 1A domain containing protein (eIF1AD)-like, S1-like RNA-binding domain. eIF1AD is also known as MGC11102 protein. Little is known about the function of eIF1AD. S1-like RNA-binding domains are found...; cd05792
S1_eIF1AD_like: eukaryotic translation initiation factor 1A domain containing protein (eIF1AD)-like, S1-like RNA-binding domain. eIF1AD is also known as MGC11102 protein. Little is known about the function of eIF1AD. S1-like RNA-binding domains are found...; cd05792
S1_eIF1AD_like: eukaryotic translation initiation factor 1A domain containing protein (eIF1AD)-like, S1-like RNA-binding domain. eIF1AD is also known as MGC11102 protein. Little is known about the function of eIF1AD. S1-like RNA-binding domains are found...; cd05792
S1_eIF1AD_like: eukaryotic translation initiation factor 1A domain containing protein (eIF1AD)-like, S1-like RNA-binding domain. eIF1AD is also known as MGC11102 protein. Little is known about the function of eIF1AD. S1-like RNA-binding domains are found...; cd05792
Barrier to autointegration factor; smart01023
Barrier to autointegration factor; smart01023
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains; cd00042
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Galactose-3-O-sulfotransferase; pfam06990
SAP domain; pfam02037
Domain of unknown function (DUF382); pfam04037
proline-rich domain in spliceosome associated proteins; smart00581
PACS-1 cytosolic sorting protein; pfam10254
Rabaptin-like protein; pfam09311
Protein of unknown function (DUF2869); pfam11068
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Rabaptin-like protein; pfam09311
Protein of unknown function (DUF2869); pfam11068
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Rabaptin-like protein; pfam09311
Protein of unknown function (DUF2869); pfam11068
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Rabaptin-like protein; pfam09311
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Rab family protein; Provisional
Rab GTPase family 1 includes the yeast homolog Ypt1; cd01869
Cornichon protein; pfam03311
YIF1; pfam03878
C-type lectin-like domain (CTLD) of the type found in human thrombomodulin(TM), Endosialin, C14orf27, and C1qR; cd03600
Complement Clr-like EGF-like; pfam12662
Trypsin Inhibitor like cysteine rich domain; pfam01826
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Src homology 2 (SH2) domain found in Ras and Rab interactor 1 (RIN1)-like proteins; cd10393
Domain present in VPS9; smart00167
Ubiquitin-like proteins; cl00155
Sds3-like; pfam08598
Sds3-like; pfam08598
Glycosyl-transferase for dystroglycan; pfam13896
Equilibrative Nucleoside Transporter (ENT); TIGR00939
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Ribosomal protein L11/L12; smart00649
Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; cd00349
Ribosomal protein L11/L12; smart00649
Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; cd00349
Ribosomal protein L11/L12; smart00649
Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; cd00349
Pellino; pfam04710
Pellino; pfam04710
Pellino; pfam04710
Pellino; pfam04710
Peptidase family M49; pfam03571
Peptidase family M49; pfam03571
Peptidase family M49; pfam03571
DHHC palmitoyltransferase; pfam01529
Cathepsin propeptide inhibitor domain (I29); smart00848
Peptidase C1A subfamily (MEROPS database nomenclature); composed of cysteine peptidases (CPs) similar to papain, including the mammalian CPs (cathepsins B, C, F, H, L, K, O, S, V, X and W). Papain is an endopeptidase with specific substrate preferences; cd02248
Microtubule associated protein (MAP65/ASE1 family); pfam03999
copper, zinc superoxide dismutase
Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; cd00371
Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; cd00305
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zinc knuckle; pfam00098
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
polyadenylate binding protein, human types 1, 2, 3, 4 family; TIGR01628
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zinc knuckle; pfam00098
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zinc knuckle; pfam00098
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats; smart00150
Beta-spectrin pleckstrin homology (PH) domain; cd01253
CAAX protease self-immunity; pfam02517
CAAX protease self-immunity; pfam02517
pyruvate carboxylase; Reviewed
Carbamoyl-phosphate synthase L chain, N-terminal domain; pfam00289
ATP-grasp domain; cl03087
Biotin carboxylase C-terminal domain; smart00878
Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; cd07937
The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; cd06850
pyruvate carboxylase; Reviewed
Carbamoyl-phosphate synthase L chain, N-terminal domain; pfam00289
ATP-grasp domain; cl03087
Biotin carboxylase C-terminal domain; smart00878
Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; cd07937
The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; cd06850
pyruvate carboxylase; Reviewed
Carbamoyl-phosphate synthase L chain, N-terminal domain; pfam00289
ATP-grasp domain; cl03087
Biotin carboxylase C-terminal domain; smart00878
Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; cd07937
The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; cd06850
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Immunoglobulin I-set domain; pfam07679
Subgroup of the immunoglobulin (Ig) superfamily; cd05764
Fibronectin type III domain; pfam00041
C2 domain; cl14603
C2 domain second repeat present in Synaptotagmin 12; cd08406
C2 domain; cl14603
C2 domain second repeat present in Synaptotagmin 12; cd08406
Ras homology family 4 (Rho4) of small guanosine triphosphatases (GTPases)-like; cd04132
GTPase SAR1 and related small G proteins [General function prediction only]
JmjC domain, hydroxylase; cl15814
CXXC zinc finger domain; pfam02008
PHD zinc finger; smart00249
F-box-like; pfam12937
Antagonist of mitotic exit network protein 1; cl15308
CXXC zinc finger domain; pfam02008
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cl15348
F-box-like; pfam12937
Antagonist of mitotic exit network protein 1; cl15308
Regulator of G protein signaling domain (RGS) found in G protein-coupled receptor kinase 2 (GRK2) and  G protein-coupled receptor kinase 3 (GRK3); cd08747
Protein kinase domain; pfam00069
Catalytic domain of the Protein Serine/Threonine Kinase, beta-adrenergic receptor kinase; cd05606
Extension to Ser/Thr-type protein kinases; smart00133
Beta adrenergic receptor kinase 1(beta ARK1)(GRK2) pleckstrin homology (PH) domain; cd01240
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
GPCR-chaperone; pfam11904
N-terminal domain conserved in slingshot (SSH) phosphatases; cd11652
DEK C terminal domain; pfam08766
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
DNA polymerase delta, subunit 4; pfam04081
DNA polymerase delta, subunit 4; pfam04081
Plethodontid receptivity factor PRF; cl03103
Plethodontid receptivity factor PRF; cl03103
Proliferating Cell Nuclear Antigen (PCNA) domain found in eukaryotes and archaea.  These polymerase processivity factors play a role in DNA replication and repair.  PCNA encircles duplex DNA in its central cavity, providing a DNA-bound platform for the...; cd00577
Rad9; pfam04139
Proliferating Cell Nuclear Antigen (PCNA) domain found in eukaryotes and archaea.  These polymerase processivity factors play a role in DNA replication and repair.  PCNA encircles duplex DNA in its central cavity, providing a DNA-bound platform for the...; cl09515
Rad9; pfam04139
PP1, PPKL (PP1 and kelch-like) enzymes,  and related proteins, metallophosphatase domain; cd07414
Calcineurin-like phosphoesterase; pfam00149
serine/threonine-protein phosphatase; Provisional
PP1, PPKL (PP1 and kelch-like) enzymes,  and related proteins, metallophosphatase domain; cd07414
serine/threonine-protein phosphatase; Provisional
PP1, PPKL (PP1 and kelch-like) enzymes,  and related proteins, metallophosphatase domain; cd07414
GTPase-activating protein [General function prediction only]
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
ATP-grasp domain; pfam13535
ATP-grasp domain; pfam13535
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, 70 kDa ribosomal protein S6 kinase; cd05584
Domain of unknown function (DUF1899); pfam08953
coronin; Provisional
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Domain of unknown function (DUF1900); pfam08954
Domain of unknown function (DUF1899); pfam08953
coronin; Provisional
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Domain of unknown function (DUF1900); pfam08954
PT repeat; pfam04886
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Eukaryotic protein of unknown function (DUF872); pfam05915
Eukaryotic protein of unknown function (DUF872); pfam05915
Eukaryotic protein of unknown function (DUF872); pfam05915
FKBP-type peptidyl-prolyl cis-trans isomerase; pfam00254
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Lipid-binding SRPBCC domain of mammalian PITPNM1-2 and related proteins (Class IIA PITPs); cd08889
DDHD domain; pfam02862
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
LNS2 (Lipin/Ned1/Smp2); pfam08235
Lipid-binding SRPBCC domain of mammalian PITPNM1-2 and related proteins (Class IIA PITPs); cd08889
DDHD domain; pfam02862
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
LNS2 (Lipin/Ned1/Smp2); pfam08235
Cyclin-dependent kinase 2-associated protein; pfam09806
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
GST_N family, Class Pi subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; cd03076
glutathione s-transferase; Provisional
C-terminal, alpha helical domain of Class Pi Glutathione S-transferases; cd03210
NADH dehydrogenase I subunit F; Provisional
SLBB domain; pfam10531
NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; smart00928
NADH dehydrogenase I subunit F; Provisional
SLBB domain; pfam10531
NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; smart00928
Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; cd03426
Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; cd03426
T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA...; cd00182
Succinylglutamate desuccinylase / Aspartoacylase family; pfam04952
Peptidase M14 Aspartoacylase (ASPA) subfamily; cd06909
NAD(P)+-dependent aldehyde dehydrogenase superfamily; cl11961
NAD(P)+-dependent aldehyde dehydrogenase superfamily; cl11961
Ion channel regulatory protein UNC-93; pfam05978
aldehyde dehydrogenase family protein; Provisional
Aldehyde dehydrogenase family 3 members A1, A2, and B1 and related proteins; cd07132
aldehyde dehydrogenase family protein; Provisional
Aldehyde dehydrogenase family 3 members A1, A2, and B1 and related proteins; cd07132
aldehyde dehydrogenase family protein; Provisional
Aldehyde dehydrogenase family 3 members A1, A2, and B1 and related proteins; cd07132
NADH dehydrogenase subunit I; Provisional
4Fe-4S binding domain; pfam00037
4Fe-4S binding domain; pfam00037
V-type ATPase 116kDa subunit family; pfam01496
V-type ATPase 116kDa subunit family; pfam01496
choline kinase
Choline Kinase (ChoK) in eukaryotes. The ChoK subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK); cd05156
choline kinase
Choline Kinase (ChoK) in eukaryotes. The ChoK subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK); cd05156
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; cl10508
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; cl10508
Low-density lipoprotein-receptor YWTD domain; smart00135
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
SIT4 phosphatase-associated protein; pfam04499
SIT4 phosphatase-associated protein; pfam04499
SIT4 phosphatase-associated protein; pfam04499
SIT4 phosphatase-associated protein; pfam04499
SIT4 phosphatase-associated protein; pfam04499
SIT4 phosphatase-associated protein; pfam04499
Galanin; smart00071
Galanin; pfam01296
Galanin message associated peptide (GMAP); pfam06540
Tesmin/TSO1-like CXC domain; pfam03638
Choline/Carnitine o-acyltransferase; pfam00755
Choline/Carnitine o-acyltransferase; pfam00755
Ribosomal prokaryotic L21 protein; pfam00829
Ribosomal prokaryotic L21 protein; pfam00829
DNA helicase, putative
AAA domain; pfam13086
AAA domain; pfam13087
R3H domain of Smubp-2_like proteins.  Smubp-2_like proteins also contain a helicase_like and an AN1-like Zinc finger domain and have been shown to bind single-stranded DNA. The name of the R3H domain comes from the characteristic spacing of the most...; cd02641
AN1-like Zinc finger; smart00154
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Cyclin, C-terminal domain; pfam02984
Essential protein Yae1, N terminal; pfam09811
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
Calcium-activated chloride channel; pfam04547
Death Effector Domain found in Fas-Associated via Death Domain; cd08336
Fas-associated Death Domain protein-protein interaction domain; cd08306
SAM domain of liprin-alpha1,2,3,4 proteins repeat 1; cd09562
Sterile alpha motif; smart00454
SAM domain of liprin-alpha1,2,3,4 proteins repeat 2; cd09565
Sterile alpha motif; smart00454
SAM domain of liprin-alpha1,2,3,4 proteins repeat 3; cd09568
Sterile alpha motif; smart00454
SAM domain of liprin-alpha1,2,3,4 proteins repeat 1; cd09562
Sterile alpha motif; smart00454
SAM domain of liprin-alpha1,2,3,4 proteins repeat 2; cd09565
Sterile alpha motif; smart00454
SAM domain of liprin-alpha1,2,3,4 proteins repeat 3; cd09568
Sterile alpha motif; smart00454
Repeat in HS1/Cortactin; pfam02218
Repeat in HS1/Cortactin; pfam02218
Repeat in HS1/Cortactin; pfam02218
Repeat in HS1/Cortactin; pfam02218
Repeat in HS1/Cortactin; pfam02218
Repeat in HS1/Cortactin; pfam02218
Src homology 3 domain of Cortactin; cd11959
Repeat in HS1/Cortactin; pfam02218
Repeat in HS1/Cortactin; pfam02218
Repeat in HS1/Cortactin; pfam02218
Repeat in HS1/Cortactin; pfam02218
Repeat in HS1/Cortactin; pfam02218
Repeat in HS1/Cortactin; pfam02218
Repeat in HS1/Cortactin; pfam02218
Src homology 3 domain of Cortactin; cd11959
Repeat in HS1/Cortactin; pfam02218
Repeat in HS1/Cortactin; pfam02218
Repeat in HS1/Cortactin; pfam02218
Repeat in HS1/Cortactin; pfam02218
Repeat in HS1/Cortactin; pfam02218
Repeat in HS1/Cortactin; pfam02218
Src homology 3 domain of Cortactin; cd11959
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2; cd11983
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
SAM domain of Shank1,2,3 family proteins; cd09506
Sterile alpha motif; smart00454
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
SAM domain of Shank1,2,3 family proteins; cd09506
Sterile alpha motif; smart00454
Phospholipid methyltransferase; cl00763
Phospholipid methyltransferase; cl00763
NAD+ synthase (glutamine-hydrolysing)
Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); cd07570
NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; cd00553
Beta defensin; pfam13841
Beta defensin; pfam13841
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Orthopoxvirus interleukin 18 binding protein; cl15707
Orthopoxvirus interleukin 18 binding protein; cl15707
Orthopoxvirus interleukin 18 binding protein; cl15707
Orthopoxvirus interleukin 18 binding protein; cl15707
Orthopoxvirus interleukin 18 binding protein; cl15707
Orthopoxvirus interleukin 18 binding protein; cl15707
chromosome segregation protein SMC, common bacterial type; TIGR02168
chromosome segregation protein SMC, common bacterial type; TIGR02168
chromosome segregation protein SMC, common bacterial type; TIGR02168
transcriptional regulator ICP4; Provisional
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Folate receptor family; pfam03024
Folate receptor family; pfam03024
Folate receptor family; pfam03024
Folate receptor family; pfam03024
Folate receptor family; pfam03024
Folate receptor family; pfam03024
Folate receptor family; pfam03024
Folate receptor family; pfam03024
Folate receptor family; pfam03024
Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP); cd10343
Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol 5-phosphatase-2 and related proteins; cd09101
SAM domain of Ship2 lipid phosphatase proteins; cd09491
Sterile alpha motif; smart00454
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
C-terminal, D2-small domain, of ClpB protein; pfam10431
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
C-terminal, D2-small domain, of ClpB protein; pfam10431
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
C-terminal, D2-small domain, of ClpB protein; pfam10431
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
C-terminal, D2-small domain, of ClpB protein; smart01086
Domain present in phytochromes and cGMP-specific phosphodiesterases; smart00065
Domain present in phytochromes and cGMP-specific phosphodiesterases; smart00065
GAF domain; pfam13185
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Domain present in phytochromes and cGMP-specific phosphodiesterases; smart00065
Domain present in phytochromes and cGMP-specific phosphodiesterases; smart00065
GAF domain; pfam13185
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Domain present in phytochromes and cGMP-specific phosphodiesterases; smart00065
Domain present in phytochromes and cGMP-specific phosphodiesterases; smart00065
GAF domain; pfam13185
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Domain present in phytochromes and cGMP-specific phosphodiesterases; smart00065
Domain present in phytochromes and cGMP-specific phosphodiesterases; smart00065
GAF domain; pfam13185
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
SAM domain of Arap1,2,3 (angiotensin receptor-associated protein); cd09490
Sterile alpha motif; smart00454
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
Putative GTPase activating protein for Arf; pfam01412
Pleckstrin homology (PH) domain; cd00821
RhoGAP_ARAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their...; cd04385
GTPase-activator protein for Rho-like GTPases; smart00324
Ras association (RalGDS/AF-6) domain; pfam00788
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
Putative GTPase activating protein for Arf; pfam01412
Pleckstrin homology (PH) domain; cd00821
RhoGAP_ARAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their...; cd04385
GTPase-activator protein for Rho-like GTPases; smart00324
Ras association (RalGDS/AF-6) domain; pfam00788
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
Putative GTPase activating protein for Arf; pfam01412
Pleckstrin homology (PH) domain; cd00821
RhoGAP_ARAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in ARAPs. ARAPs (also known as centaurin deltas) contain, besides the RhoGAP domain, an Arf GAP, ankyrin repeat ras-associating, and PH domains. Since their...; cd04385
GTPase-activator protein for Rho-like GTPases; smart00324
Ras association (RalGDS/AF-6) domain; pfam00788
Pleckstrin homology (PH) domain; cd00821
Lipid-binding START domain of mammalian STARD10 and related proteins; cd08871
Autophagy protein 16 (ATG16); pfam08614
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH and double SH3 domains 2 (FCHSD2); cd07677
First Src Homology 3 domain of FCH and double SH3 domains proteins; cd11761
Second Src Homology 3 domain of FCH and double SH3 domains protein 2; cd11894
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Tumour necrosis factor receptor superfamily member 19; pfam12606
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Tumour necrosis factor receptor superfamily member 19; pfam12606
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
GTPase SAR1 and related small G proteins [General function prediction only]
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Rab family protein; Provisional
Rab GTPase family 6 (Rab6); cd01861
Rab family protein; Provisional
Rab GTPase family 6 (Rab6); cd01861
Rab GTPase family 6 (Rab6); cd01861
Ribosomal protein S10p/S20e; pfam00338
CHCH domain; pfam06747
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]; COG0484
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
C-terminal substrate binding domain of DnaJ and HSP40; cd10747
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
C2 domain found in C2 calcium-dependent domain containing 3 (C2cd3) proteins; cd08683
C2 domain; cd00030
Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; COG0596
Prolyl 4-Hydroxylase alpha-subunit, N-terminal region; pfam08336
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam03171
phosphoglucomutase-2-like protein; Provisional
This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; cd05799
Slow voltage-gated potassium channel; pfam02060
Biotin/lipoate A/B protein ligase family; cl14057
DNA polymerase subunit Cdc27; pfam09507
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; pfam00093
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Microsomal signal peptidase 25 kDa subunit (SPC25); pfam06703
Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; cd00260
BNR repeat-like domain; pfam13088
Olfactory receptor; pfam13853
Organic Anion Transporter Polypeptide (OATP) family; pfam03137
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a...; cd01330
Organic Anion Transporter Polypeptide (OATP) family; pfam03137
The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a...; cd01330
Organic Anion Transporter Polypeptide (OATP) family; pfam03137
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a...; cd01330
Leucine rich repeat; pfam13855
Arrestin (or S-antigen), N-terminal domain; pfam00339
Arrestin (or S-antigen), C-terminal domain; smart01017
Arrestin (or S-antigen), N-terminal domain; pfam00339
Arrestin (or S-antigen), C-terminal domain; smart01017
40S ribosomal protein S3; Provisional
K homology RNA-binding (KH) domain of the eukaryotic 40S small ribosomal subunit protein S3. S3  is part of the head region of the 40S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; cd02413
Ribosomal protein S3, C-terminal domain; pfam00189
40S ribosomal protein S3; Provisional
K homology RNA-binding (KH) domain of the eukaryotic 40S small ribosomal subunit protein S3. S3  is part of the head region of the 40S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; cd02413
Ribosomal protein S3, C-terminal domain; pfam00189
40S ribosomal protein S3; Provisional
K homology RNA-binding (KH) domain of the eukaryotic 40S small ribosomal subunit protein S3. S3  is part of the head region of the 40S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; cd02413
Ribosomal protein S3, C-terminal domain; pfam00189
Ribosomal protein S3, C-terminal domain; pfam00189
BTB/POZ domain; pfam00651
BTB And C-terminal Kelch; smart00875
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch motif; pfam01344
Kelch motif; pfam01344
Galactose oxidase, central domain; cl02701
Galactose oxidase, central domain; cl02701
Glycerophosphodiester phosphodiesterase domain of mammalian glycerophosphodiester phosphodiesterase GDE2 and similar proteins; cd08608
Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; COG0584
SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate...; cl00137
SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate...; cl00137
STOP protein; pfam05217
Herpesvirus latent membrane protein 1 (LMP1); pfam05297
Herpesvirus latent membrane protein 1 (LMP1); pfam05297
STOP protein; pfam05217
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; cd07987
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; cd07987
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; cd07987
C2 domain; cl14603
UV radiation resistance protein and autophagy-related subunit 14; pfam10186
wnt family; pfam00110
found in Wnt-1; smart00097
THAP domain; pfam05485
hAT family dimerisation domain; pfam05699
ENT domain; pfam03735
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Ceramidase; pfam05875
Galactosyltransferase; cl09537
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction; cd00044
Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are...; cd00214
C2 domain present in Calpain proteins; cd04046
Olfactory marker protein; pfam06554
Myosin. Large ATPases; smart00242
Myosin motor domain, type VII myosins. Myosins in this group have been associated with functions in sensory systems such as vision and hearing. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins...; cd01381
IQ calmodulin-binding motif; cl15479
MyTH4 domain; cl02480
MyTH4 domain; pfam00784
Band 4.1 homologues; smart00295
FERM central domain; pfam00373
Src Homology 3 domain superfamily; cl17036
Domain in Myosin and Kinesin Tails; smart00139
Band 4.1 homologues; smart00295
FERM central domain; pfam00373
Myosin. Large ATPases; smart00242
Myosin motor domain, type VII myosins. Myosins in this group have been associated with functions in sensory systems such as vision and hearing. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins...; cd01381
IQ calmodulin-binding motif; cl15479
MyTH4 domain; cl02480
MyTH4 domain; pfam00784
Band 4.1 homologues; smart00295
FERM central domain; pfam00373
Src Homology 3 domain superfamily; cl17036
Domain in Myosin and Kinesin Tails; smart00139
Band 4.1 homologues; smart00295
FERM central domain; pfam00373
Myosin. Large ATPases; smart00242
Myosin motor domain, type VII myosins. Myosins in this group have been associated with functions in sensory systems such as vision and hearing. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins...; cd01381
IQ calmodulin-binding motif; cl15479
MyTH4 domain; cl02480
Glycerophosphodiester phosphodiesterase domain of mammalian glycerophosphodiester phosphodiesterase GDE6 and similar proteins; cd08610
Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; COG0584
PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the...; cd01093
Catalytic domain of the Protein Serine/Threonine Kinase, Group I p21-activated kinase; cd06647
Serine/Threonine protein kinases, catalytic domain; smart00220
PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the...; cd01093
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; cl00200
Nucleotide-sensitive chloride conductance regulator (ICln); pfam03517
PHD-finger; pfam00628
Mth938 domain. Mth938 is a hypothetical protein encoded by the Methanobacterium thermoautotrophicum (Mth) genome. This protein crystallizes as a dimer, although it is monomeric in solution, with one disulfide bond in each monomer. The function of the...; cd05126
Adaptin N terminal region; pfam01602
BTB/POZ domain; cl02518
NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2); pfam06374
NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2); pfam06374
NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2); pfam06374
Thyroid hormone-inducible hepatic protein Spot 14; pfam07084
NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2); pfam06374
NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2); pfam06374
NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2); pfam06374
ALG6, ALG8 glycosyltransferase family; pfam03155
ALG6, ALG8 glycosyltransferase family; pfam03155
K+ channel tetramerisation domain; pfam02214
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Gab (Grb2-associated binder) pleckstrin homology (PH) domain; cd01266
variable surface protein Vir27; Provisional
Pleckstrin homology-like domain; cl00273
variable surface protein Vir27; Provisional
asparaginyl-tRNA synthetase; Validated; PRK03932
EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; cd04318
Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; cd00776
Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it attaches...; cl00268
Teneurin Intracellular Region; pfam06484
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
RHS Repeat; pfam05593
Rhs family protein [Cell envelope biogenesis, outer membrane]; COG3209
RHS repeat-associated core domain; TIGR03696
Serine carboxypeptidase S28; cl15279
Alpha/beta hydrolase family; pfam12697
Serine carboxypeptidase S28; cl15279
Alpha/beta hydrolase family; pfam12697
RPA1_DBD_C: A subfamily of OB folds corresponding to the C-terminal OB fold, the ssDNA-binding domain (DBD)-C, of human RPA1 (also called RPA70). RPA1 is the large subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which...; cd04476
Rab GTPase family 30 (Rab30); cd04114
Rab family protein; Provisional
CID (CTD-Interacting Domain) domain family; CID is present in several RNA-processing factors such as Pcf11 and Nrd1. Pcf11 is a conserved and essential subunit of the yeast cleavage factor IA, which is required for polyadenylation-dependent 3'-RNA...; cd03562
Invertebrate innate immunity transcript family; pfam12782
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Protein of unknown function (DUF1640); pfam07798
L27 domain; cl02672
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ-associated domain of NMDA receptors; pfam10600
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain of Disks Large homolog 2; cd12032
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ-associated domain of NMDA receptors; pfam10600
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain of Disks Large homolog 2; cd12032
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ-associated domain of NMDA receptors; pfam10600
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain of Disks Large homolog 2; cd12032
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ-associated domain of NMDA receptors; pfam10600
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain of Disks Large homolog 2; cd12032
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
Src Homology 3 domain superfamily; cl17036
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
Protein of unknown function (DUF1370); pfam07114
Protein of unknown function (DUF1370); pfam07114
Protein of unknown function (DUF1370); pfam07114
Protein of unknown function (DUF1370); pfam07114
Protein of unknown function (DUF1370); pfam07114
Protein of unknown function (DUF1370); pfam07114
Protein of unknown function (DUF1370); pfam07114
chromosome segregation protein SMC, common bacterial type; TIGR02168
C2 domain first repeat present in Synaptotagmin-like proteins 1 and 2; cd08393
C2 domain second repeat present in Synaptotagmin-like proteins 1-4; cd04020
C2 domain first repeat present in Synaptotagmin-like proteins 1 and 2; cd08393
C2 domain second repeat present in Synaptotagmin-like proteins 1-4; cd04020
C2 domain first repeat present in Synaptotagmin-like proteins 1 and 2; cd08393
C2 domain second repeat present in Synaptotagmin-like proteins 1-4; cd04020
C2 domain first repeat present in Synaptotagmin-like proteins 1 and 2; cd08393
C2 domain second repeat present in Synaptotagmin-like proteins 1-4; cd04020
C2 domain first repeat present in Synaptotagmin-like proteins 1 and 2; cd08393
C2 domain second repeat present in Synaptotagmin-like proteins 1-4; cd04020
C2 domain first repeat present in Synaptotagmin-like proteins 1 and 2; cd08393
C2 domain second repeat present in Synaptotagmin-like proteins 1-4; cd04020
C2 domain first repeat present in Synaptotagmin-like proteins 1 and 2; cd08393
C2 domain second repeat present in Synaptotagmin-like proteins 1-4; cd04020
C2 domain first repeat present in Synaptotagmin-like proteins 1 and 2; cd08393
C2 domain second repeat present in Synaptotagmin-like proteins 1-4; cd04020
C2 domain first repeat present in Synaptotagmin-like proteins 1 and 2; cd08393
C2 domain second repeat present in Synaptotagmin-like proteins 1-4; cd04020
ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet...; cd03564
ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet...; cd03564
ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet...; cd03564
ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet...; cd03564
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Protein of unknown function (DUF775); pfam05603
chromosome segregation protein SMC, common bacterial type; TIGR02168
NADP-dependent malic enzyme; Provisional
Malic enzyme, N-terminal domain; pfam00390
NAD(P) binding domain of malic enzyme (ME), subgroup 1; cd05312
NADP-dependent malic enzyme; Provisional
Malic enzyme, N-terminal domain; pfam00390
NAD(P) binding domain of malic enzyme (ME), subgroup 1; cd05312
NADP-dependent malic enzyme; Provisional
Malic enzyme, N-terminal domain; pfam00390
NAD(P) binding domain of malic enzyme (ME), subgroup 1; cd05312
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cl00149
Cysteine-rich Wnt-binding domain of the frizzled 4 (Fz4) receptor; cd07448
Frizzled/Smoothened family membrane region; pfam01534
Tim17/Tim22/Tim23/Pmp24 family; pfam02466
Tim17/Tim22/Tim23/Pmp24 family; pfam02466
Rab GTPase families 18 (Rab18) and 32 (Rab32); cd04107
rab6; Provisional
Cathepsin C exclusion domain; pfam08773
Cathepsin C; also known as Dipeptidyl Peptidase I (DPPI), an atypical papain-like cysteine peptidase with chloride dependency and dipeptidyl aminopeptidase activity, resulting from its tetrameric structure which limits substrate access. Each subunit of...; cd02621
Cathepsin C exclusion domain; pfam08773
Cathepsin C exclusion domain; pfam08773
Ligand binding domain of the group I metabotropic glutamate receptor; cd06374
Receptor family ligand binding region; pfam01094
Nine Cysteines Domain of family 3 GPCR; pfam07562
7 transmembrane sweet-taste receptor of 3 GCPR; pfam00003
Homer-binding domain of metabotropic glutamate receptor; pfam10606
Ligand binding domain of the group I metabotropic glutamate receptor; cd06374
Receptor family ligand binding region; pfam01094
Nine Cysteines Domain of family 3 GPCR; pfam07562
7 transmembrane sweet-taste receptor of 3 GCPR; pfam00003
Homer-binding domain of metabotropic glutamate receptor; pfam10606
Common central domain of tyrosinase; pfam00264
Ferric reductase like transmembrane component; pfam01794
NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX...; cd06186
Ferric reductase like transmembrane component; pfam01794
NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX...; cd06186
Ferric reductase like transmembrane component; pfam01794
NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX...; cd06186
Predicted aminopeptidases [General function prediction only]; COG2234
M28 Zn-peptidase prostate-specific membrane antigen; cd08022
Transferrin receptor-like dimerisation domain; pfam04253
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Domain in SPla and the RYanodine Receptor; smart00449
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
Zinc peptidases M18, M20, M28, and M42; cl14876
PA_GCPII_like: Protease-associated domain containing protein, glutamate carboxypeptidase II (GCPII)-like. This group contains various PA domain-containing proteins similar to GCPII including, GCPIII (NAALADase2) and NAALADase L. These proteins belong to...; cd02121
Predicted aminopeptidases [General function prediction only]; COG2234
M28 Zn-peptidase prostate-specific membrane antigen; cd08022
Transferrin receptor-like dimerisation domain; pfam04253
CHORD; pfam04968
CHORD; pfam04968
p23_like domain similar to the C-terminal (tail) domain of vertebrate Melusin and related proteins. Melusin's tail domain interacts with the cytoplasmic domain of beta1-A and beta1-D isoforms of beta1 integrin, it does not bind other integrin beta...; cd06488
CHORD; pfam04968
CHORD; pfam04968
p23_like domain similar to the C-terminal (tail) domain of vertebrate Melusin and related proteins. Melusin's tail domain interacts with the cytoplasmic domain of beta1-A and beta1-D isoforms of beta1 integrin, it does not bind other integrin beta...; cd06488
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; cl10458
Transmembrane amino acid transporter protein; pfam01490
Amino acid permeases [Amino acid transport and metabolism]; COG0814
chromosome segregation protein SMC, common bacterial type; TIGR02168
Domain of Unknown Function (DUF1907); pfam08925
Subunit 17 of Mediator complex; pfam10156
Immunoglobulin domain; cl11960
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Multicopper oxidase; pfam07731
Folate receptor family; pfam03024
7 transmembrane receptor (rhodopsin family); pfam00001
DNA repair protein (mre11); TIGR00583
Mre11 nuclease, N-terminal metallophosphatase domain; cd00840
Mre11 DNA-binding presumed domain; pfam04152
DNA repair protein (mre11); TIGR00583
Mre11 nuclease, N-terminal metallophosphatase domain; cd00840
Mre11 DNA-binding presumed domain; pfam04152
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13857
Glycosyltransferase family 10 (fucosyltransferase); pfam00852
PAZ domain,  Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the...; cd02845
Piwi_piwi-like_Euk: PIWI domain, Piwi-like subfamily found in eukaryotes. This domain is found in Piwi and closely related proteins, where it is believed to perform a crucial role in germline cells, via RNA silencing. RNA silencing refers to a group of...; cd04658
Angiomotin C terminal; pfam12240
Cwf15/Cwc15 cell cycle control protein; pfam04889
Cwf15/Cwc15 cell cycle control protein; pfam04889
jmjN domain; pfam02375
JmjC domain, hydroxylase; pfam02373
jmjN domain; pfam02375
JmjC domain, hydroxylase; pfam02373
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
DNA/RNA non-specific endonuclease; smart00892
DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; cd00091
PA26 p53-induced protein (sestrin); pfam04636
phosphodiesterase; Provisional
Centrosome localisation domain of Cep57; pfam14073
Centrosome microtubule-binding domain of Cep57; pfam06657
Centrosome localisation domain of Cep57; pfam14073
Centrosome microtubule-binding domain of Cep57; pfam06657
Centrosome localisation domain of Cep57; pfam14073
Centrosome microtubule-binding domain of Cep57; pfam06657
GRAM domain; pfam02893
Myotubularin-related; pfam06602
Myotubularin Y_phosphatase-like; pfam13849
GRAM domain; pfam02893
Myotubularin-related; pfam06602
Myotubularin Y_phosphatase-like; pfam13849
GRAM domain; pfam02893
Myotubularin-related; pfam06602
Myotubularin Y_phosphatase-like; pfam13849
GRAM domain; pfam02893
Myotubularin-related; pfam06602
Myotubularin Y_phosphatase-like; pfam13849
MamL-1 domain; pfam09596
Domain of unknown function (DUF4196); pfam13846
Domain of unknown function (DUF4211); pfam13926
Putative DNA-binding domain in centromere protein B, mouse jerky and transposases; smart00674
DDE superfamily endonuclease; pfam03184
Putative DNA-binding domain in centromere protein B, mouse jerky and transposases; smart00674
DDE superfamily endonuclease; pfam03184
First Ig domain of contactin-5; cd05848
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Fifth Ig domain of contactin; cd04969
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
First Ig domain of contactin-5; cd05848
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Fifth Ig domain of contactin; cd04969
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
First Ig domain of contactin-5; cd05848
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Fifth Ig domain of contactin; cd04969
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
First Ig domain of contactin-5; cd05848
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Fifth Ig domain of contactin; cd04969
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
The Bin/Amphiphysin/Rvs (BAR) domain of Rho GTPase activating protein 10-like; cd07634
Pleckstrin homology-like domain; cl00273
RhoGAP_Graf: GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences...; cd04374
GTPase-activator protein for Rho-like GTPases; smart00324
Src Homology 3 domain of GTPase Regulator Associated with Focal adhesion kinase 3; cd12066
Progesterone receptor; pfam02161
Progesterone receptor; pfam02161
DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers; cd07172
Ligand binding domain of the progesterone receptor, a member of the nuclear hormone receptor; cd07074
Progesterone receptor; pfam02161
Progesterone receptor; pfam02161
DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers; cd07172
The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators; cl11397
Progesterone receptor; pfam02161
Progesterone receptor; pfam02161
DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers; cd07172
Ligand binding domain of the progesterone receptor, a member of the nuclear hormone receptor; cd07074
DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers; cl02596
Ligand binding domain of the progesterone receptor, a member of the nuclear hormone receptor; cd07074
transient-receptor-potential calcium channel protein; TIGR00870
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Transient receptor ion channel II; pfam08344
Polycystin cation channel; pfam08016
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Caspase activation and recruitment domain found in Baculoviral IAP repeat-containing proteins, BIRC2 (c-IAP1) and BIRC3 (c-IAP2); cd08329
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Caspase activation and recruitment domain found in Baculoviral IAP repeat-containing proteins, BIRC2 (c-IAP1) and BIRC3 (c-IAP2); cd08329
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Caspase activation and recruitment domain found in Baculoviral IAP repeat-containing proteins, BIRC2 (c-IAP1) and BIRC3 (c-IAP2); cd08329
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Caspase activation and recruitment domain found in Baculoviral IAP repeat-containing proteins, BIRC2 (c-IAP1) and BIRC3 (c-IAP2); cd08329
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Caspase activation and recruitment domain found in Baculoviral IAP repeat-containing proteins, BIRC2 (c-IAP1) and BIRC3 (c-IAP2); cd08329
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
Putative peptidoglycan binding domain; pfam01471
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate...; cd04278
Putative peptidoglycan binding domain; pfam01471
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate...; cd04278
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
Putative peptidoglycan binding domain; pfam01471
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate...; cd04278
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
Putative peptidoglycan binding domain; pfam01471
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate...; cd04278
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
Putative peptidoglycan binding domain; pfam01471
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate...; cd04278
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
Putative peptidoglycan binding domain; pfam01471
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate...; cd04278
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
Putative peptidoglycan binding domain; pfam01471
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate...; cd04278
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
Putative peptidoglycan binding domain; pfam01471
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate...; cd04278
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
Putative peptidoglycan binding domain; pfam01471
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate...; cd04278
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
Putative peptidoglycan binding domain; pfam01471
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate...; cd04278
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
Cullin binding; pfam03556
Dynein heavy chain, N-terminal region 1; pfam08385
Dynein heavy chain, N-terminal region 2; pfam08393
Hydrolytic ATP binding site of dynein motor region D1; pfam12774
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
AAA domain (dynein-related subfamily); pfam07728
AAA domain; pfam13401
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Microtubule-binding stalk of dynein motor; pfam12777
ATP-binding dynein motor region D5; pfam12781
Dynein heavy chain and region D6 of dynein motor; pfam03028
Dynein heavy chain, N-terminal region 1; pfam08385
Dynein heavy chain, N-terminal region 2; pfam08393
Hydrolytic ATP binding site of dynein motor region D1; pfam12774
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
AAA domain (dynein-related subfamily); pfam07728
AAA domain; pfam13401
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Microtubule-binding stalk of dynein motor; pfam12777
ATP-binding dynein motor region D5; pfam12781
Dynein heavy chain and region D6 of dynein motor; pfam03028
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family domain; PDGF is a potent activator for cells of mesenchymal origin; PDGF-A and PDGF-B form AA and BB homodimers and an AB heterodimer; VEGF is a potent mitogen in embryonic and...; cd00135
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family domain; PDGF is a potent activator for cells of mesenchymal origin; PDGF-A and PDGF-B form AA and BB homodimers and an AB heterodimer; VEGF is a potent mitogen in embryonic and...; cd00135
DNA damage inducible protein 1 ubiquitin-like domain; cd01796
Ubiquitin family; pfam00240
RP_DDI; retropepsin-like domain of DNA damage inducible protein; cd05479
Caspase activation and recruitment domain found in Caspase-1 and related proteins; cd08325
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
Caspase activation and recruitment domain found in Caspase-1 and related proteins; cd08325
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
The Death Domain Superfamily of protein-protein interaction domains; cl14633
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
The Death Domain Superfamily of protein-protein interaction domains; cl14633
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
The Death Domain Superfamily of protein-protein interaction domains; cl14633
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
The Death Domain Superfamily of protein-protein interaction domains; cl14633
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cl00042
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
Caspase activation and recruitment domain found in Caspase-1 and related proteins; cd08325
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
Caspase activation and recruitment domain found in Caspase-1 and related proteins; cd08325
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
Caspase activation and recruitment domain found in Caspase-1 and related proteins; cd08325
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
Caspase activation and recruitment domain found in Caspase-1 and related proteins; cd08325
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
Caspase activation and recruitment domain found in Caspase-1 and related proteins; cd08325
Caspase activation and recruitment domain found in Caspase-1 and related proteins; cd08325
Caspase activation and recruitment domain found in Caspase-1 and related proteins; cd08325
Caspase activation and recruitment domain found in Caspase-1 and related proteins; cd08325
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the GluR4 subunit of the AMPA receptor; cd06388
Receptor family ligand binding region; pfam01094
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Ligand-gated ion channel; pfam00060
Eukaryotic homologues of bacterial periplasmic substrate binding proteins; smart00079
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the GluR4 subunit of the AMPA receptor; cd06388
Receptor family ligand binding region; pfam01094
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Ligand-gated ion channel; pfam00060
Eukaryotic homologues of bacterial periplasmic substrate binding proteins; smart00079
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the GluR4 subunit of the AMPA receptor; cd06388
Receptor family ligand binding region; pfam01094
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the GluR4 subunit of the AMPA receptor; cd06388
Receptor family ligand binding region; pfam01094
Myb/SANT-like DNA-binding domain; pfam13873
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch motif; pfam01344
Kelch motif; pfam01344
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch motif; pfam01344
Kelch motif; pfam01344
Phosphopantetheinyl transferase [Coenzyme metabolism]; COG2091
4'-phosphopantetheinyl transferase superfamily; pfam01648
Heme NO binding; cl15268
Heme NO binding associated; pfam07701
Adenylyl- / guanylyl cyclase, catalytic domain; smart00044
cyclase homology domain; cd07302
Heme NO binding; cl15268
Heme NO binding associated; pfam07701
Adenylyl- / guanylyl cyclase, catalytic domain; smart00044
cyclase homology domain; cd07302
HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; cl00228
Protein similar to CwfJ C-terminus 2; pfam04676
Domain of unknown function (DUF1891); pfam09004
2OG-Fe(II) oxygenase superfamily; cl15773
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
ELMO/CED-12 family; pfam04727
ELMO/CED-12 family; pfam04727
Sarcolipin; pfam05366
Eukaryotic protein of unknown function (DUF914); pfam06027
Rab GTPase family 39 (Rab39); cd04111
Rab family protein; Provisional
Cullin family; pfam00888
Cullin; smart00182
Cullin protein neddylation domain; pfam10557
acetyl-CoA C-acetyltransferase
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; cd00751
Telomere-length maintenance and DNA damage repair; pfam11640
FAT domain; pfam02259
Ataxia telangiectasia mutated (ATM), catalytic domain; The ATM catalytic domain subfamily is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein kinases (PKs); cd05171
Phosphoinositide 3-kinase, catalytic domain; smart00146
FATC domain; pfam02260
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; cl10013
Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; COG0513
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Domain of unknown function (DUF4217); pfam13959
Zc3h12a-like Ribonuclease NYN domain; pfam11977
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
Ezrin/radixin/moesin family; pfam00769
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
Ezrin/radixin/moesin family; pfam00769
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
Ezrin/radixin/moesin family; pfam00769
Ezrin/radixin/moesin family; pfam00769
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
Ezrin/radixin/moesin family; pfam00769
FERM central domain; pfam00373
Band 4.1 homologues; smart00295
FERM_C domain; cd00836
Ezrin/radixin/moesin family; pfam00769
2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; cd00207
Ras association (RalGDS/AF-6) domain; pfam00788
RhoGAP_ARHGAP20: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP20-like proteins. ArhGAP20, also known as KIAA1391 and RA-RhoGAP, contains a RhoGAP, a RA, and a PH domain, and ANXL repeats. ArhGAP20 is activated by...; cd04402
GTPase-activator protein for Rho-like GTPases; smart00324
Ras association (RalGDS/AF-6) domain; pfam00788
RhoGAP_ARHGAP20: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP20-like proteins. ArhGAP20, also known as KIAA1391 and RA-RhoGAP, contains a RhoGAP, a RA, and a PH domain, and ANXL repeats. ArhGAP20 is activated by...; cd04402
GTPase-activator protein for Rho-like GTPases; smart00324
Ras association (RalGDS/AF-6) domain; pfam00788
RhoGAP_ARHGAP20: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP20-like proteins. ArhGAP20, also known as KIAA1391 and RA-RhoGAP, contains a RhoGAP, a RA, and a PH domain, and ANXL repeats. ArhGAP20 is activated by...; cd04402
GTPase-activator protein for Rho-like GTPases; smart00324
Ras association (RalGDS/AF-6) domain; pfam00788
RhoGAP_ARHGAP20: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP20-like proteins. ArhGAP20, also known as KIAA1391 and RA-RhoGAP, contains a RhoGAP, a RA, and a PH domain, and ANXL repeats. ArhGAP20 is activated by...; cd04402
GTPase-activator protein for Rho-like GTPases; smart00324
Ras association (RalGDS/AF-6) domain; pfam00788
RhoGAP_ARHGAP20: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP20-like proteins. ArhGAP20, also known as KIAA1391 and RA-RhoGAP, contains a RhoGAP, a RA, and a PH domain, and ANXL repeats. ArhGAP20 is activated by...; cd04402
GTPase-activator protein for Rho-like GTPases; smart00324
POU domain, class 2, associating factor 1; pfam09310
BTG family; pfam07742
Putative binding domain; pfam13900
C-type lectin-like domain (CTLD) of the type found in the human type-1A transmembrane proteins chondrolectin (CHODL) and layilin; cd03595
C-type lectin-like domain (CTLD) of the type found in the human type-1A transmembrane proteins chondrolectin (CHODL) and layilin; cd03595
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
HEAT repeat; pfam02985
HEAT repeats; pfam13646
HEAT repeat; pfam02985
HEAT repeats; pfam13646
HEAT repeat; pfam02985
HEAT repeats; pfam13646
HEAT repeat; pfam02985
HEAT repeats; pfam13646
HEAT repeat; pfam02985
HEAT repeats; pfam13646
HEAT repeat; pfam02985
HEAT repeats; pfam13646
HEAT repeat; pfam02985
HEAT repeats; pfam13646
HEAT repeat; pfam02985
HEAT repeats; pfam13646
HEAT repeat; pfam02985
HEAT repeats; pfam13646
Alg9-like mannosyltransferase family; pfam03901
Alg9-like mannosyltransferase family; pfam03901
Dolichyl-phosphate-mannose-protein mannosyltransferase; cl15769
Dolichyl-phosphate-mannose-protein mannosyltransferase; cl15769
Domain of unknown function (DUF2431); pfam10354
Ferredoxin-fold anticodon binding domain; smart00896
Protein of unknown function (DUF1143); pfam06608
Alpha crystallin A chain, N terminal; pfam00525
Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; COG0071
Alpha-crystallin domain found in the small heat shock protein (sHsp) alphaB-crystallin (HspB5, 20kDa). sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers...; cd06498
Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; COG0071
Alpha crystallin domain (ACD) found in mammalian small heat shock protein (sHsp) HspB2/heat shock 27kDa protein 2 and similar proteins. sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally...; cd06476
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
DIX domain; pfam00778
DIX domain; pfam00778
Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; cd06849
Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; cd06849
pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; TIGR01349
e3 binding domain; pfam02817
2-oxoacid dehydrogenases acyltransferase (catalytic domain); pfam00198
pre-RNA processing PIH1/Nop17; pfam08190
This domain family includes the alpha-crystallin domain (ACD) of alpha-crystallin-type small heat shock proteins (sHsps) and a similar domain found in p23-like proteins.  sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa; cd00298
Tim10/DDP family zinc finger; pfam02953
SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Eukaryotic SQRs reduce high potential quinones such as ubiquinone. SQR is also called succinate dehydrogenase or Complex II, and is part of the citric...; cd03496
Interleukin-1 / 18; pfam00340
Interleukin-1 / 18; pfam00340
Retinal pigment epithelial membrane protein; pfam03055
Lignostilbene-alpha,beta-dioxygenase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]
Retinal pigment epithelial membrane protein; cl10080
Retinal pigment epithelial membrane protein; cl10080
Retinal pigment epithelial membrane protein; pfam03055
Lignostilbene-alpha,beta-dioxygenase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]
Retinal pigment epithelial membrane protein; pfam03055
Lignostilbene-alpha,beta-dioxygenase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]
Retinal pigment epithelial membrane protein; pfam03055
6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a...; cd00470
First immunoglobulin (Ig)-like domain of neural cell adhesion molecule NCAM-1; cd05865
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
First immunoglobulin (Ig)-like domain of neural cell adhesion molecule NCAM-1; cd05865
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Fifth immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-1 (NCAM); cd05869
Immunoglobulin domain; cd00096
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
First immunoglobulin (Ig)-like domain of neural cell adhesion molecule NCAM-1; cd05865
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Fifth immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-1 (NCAM); cd05869
Immunoglobulin domain; cd00096
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
First immunoglobulin (Ig)-like domain of neural cell adhesion molecule NCAM-1; cd05865
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Third immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-1 (NCAM); cd05730
Immunoglobulin I-set domain; pfam07679
Fifth immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-1 (NCAM); cd05869
Immunoglobulin domain; cd00096
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
First immunoglobulin (Ig)-like domain of neural cell adhesion molecule NCAM-1; cd05865
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Third immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-1 (NCAM); cd05730
Immunoglobulin I-set domain; pfam07679
Fifth immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-1 (NCAM); cd05869
Immunoglobulin domain; cd00096
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13857
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; cl10458
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Centromere/kinetochore Zw10; pfam06248
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02665
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02665
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Cation transporter family protein; TIGR00860
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Cation transporter family protein; TIGR00860
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Cation transporter family protein; TIGR00860
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Cation transporter family protein; TIGR00860
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
BTB/POZ domain; pfam00651
FOG: Zn-finger [General function prediction only]
C2H2-type zinc finger; pfam13912
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
BTB/POZ domain; pfam00651
FOG: Zn-finger [General function prediction only]
C2H2-type zinc finger; pfam13912
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; COG0847
DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; cd06135
Neurexophilin; pfam06312
Neurexophilin; pfam06312
Neurexophilin; pfam06312
First (N-terminal) immunoglobulin (Ig)-like domain of nectin-like molecule 2 (also known as cell adhesion molecule 1 (CADM1)); cd05881
Immunoglobulin V-set domain; pfam07686
Second immunoglobulin (Ig)-like domain of nectin-like molecule 2 (also known as cell adhesion molecule 1 (CADM1)); cd05883
Immunoglobulin; smart00409
First (N-terminal) immunoglobulin (Ig)-like domain of nectin-like molecule 2 (also known as cell adhesion molecule 1 (CADM1)); cd05881
Immunoglobulin V-set domain; pfam07686
Second immunoglobulin (Ig)-like domain of nectin-like molecule 2 (also known as cell adhesion molecule 1 (CADM1)); cd05883
Immunoglobulin like; smart00410
Pre-mRNA-splicing factor of RES complex; pfam09736
Pre-mRNA-splicing factor of RES complex; pfam09736
C4-type Zn-finger protein [General function prediction only]; cl00771
ZPR1 zinc-finger domain; pfam03367
ZPR1 zinc-finger domain; pfam03367
C4-type Zn-finger protein [General function prediction only]; cl00771
Apolipoprotein A1/A4/E domain; pfam01442
Apolipoprotein A1/A4/E domain; pfam01442
Apolipoprotein A1/A4/E domain; pfam01442
Gas vesicle synthesis protein GvpL/GvpF; pfam06386
Apolipoprotein CIII (Apo-CIII); pfam05778
Apolipoprotein A1/A4/E domain; pfam01442
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; cl01053
SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; cl01053
SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; cl01053
PAF_acetylhydrolase (PAF-AH)_like subfamily of SGNH-hydrolases. Platelet-activating factor (PAF) and PAF-AH are key players in inflammation and in atherosclerosis. PAF-AH is a calcium independent phospholipase A2 which exhibits strong substrate...; cd01820
dsRNA-gated channel SID-1; pfam13965
dsRNA-gated channel SID-1; pfam13965
Calponin [Cytoskeleton]; COG5199
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin family repeat; pfam00402
Calponin [Cytoskeleton]; COG5199
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin family repeat; pfam00402
Peptidase S8 family domain in Protein convertases; cd04059
Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; COG1404
Proprotein convertase P-domain; pfam01483
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Cellular and retroviral pepsin-like aspartate proteases; cl11403
Eukaryotic aspartyl protease; pfam00026
Beta-secretase, aspartic-acid protease important in the pathogenesis of Alzheimer's disease; cd05473
Eukaryotic aspartyl protease; pfam00026
Beta-secretase, aspartic-acid protease important in the pathogenesis of Alzheimer's disease; cd05473
Eukaryotic aspartyl protease; pfam00026
Beta-secretase, aspartic-acid protease important in the pathogenesis of Alzheimer's disease; cd05473
Eukaryotic aspartyl protease; pfam00026
Cellular and retroviral pepsin-like aspartate proteases; cl11403
Beta-secretase, aspartic-acid protease important in the pathogenesis of Alzheimer's disease; cd05473
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Transcriptional activator TraM; cl11943
Type III secretion protein YscO; pfam07321
Protein of unknown function (DUF2968); pfam11180
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin C-2 Type; smart00408
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Seventh immunoglobulin (Ig)-like domain of Down Syndrome Cell Adhesion molecule (DSCAM); cd05734
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin domain; cd00096
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
Scavenger receptor Cys-rich; smart00202
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Scavenger receptor Cys-rich; smart00202
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Scavenger receptor Cys-rich; smart00202
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Scavenger receptor Cys-rich; smart00202
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cl00149
Tissue factor; pfam01108
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Scavenger receptor Cys-rich; smart00202
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Scavenger receptor Cys-rich; smart00202
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Scavenger receptor Cys-rich; smart00202
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Scavenger receptor Cys-rich; smart00202
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Immunoglobulin domain; cl11960
Immunoglobulin V-Type; smart00406
Immunoglobulin domain; cl11960
Immunoglobulin (Ig)-like domain of Protein zero (P0) and similar proteins; cd05715
Immunoglobulin V-set domain; pfam07686
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain of epithelial V-like antigen 1 (EVA); cd05880
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain of epithelial V-like antigen 1 (EVA); cd05880
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain of CD3 epsilon chain; cd07692
Immunoreceptor tyrosine-based activation motif; smart00077
Immunoglobulin domain; cl11960
Immunoreceptor tyrosine-based activation motif; smart00077
Immunoglobulin (Ig)-like domain of CD3 gamma and delta chains; cd07691
Immunoreceptor tyrosine-based activation motif; smart00077
Immunoglobulin (Ig)-like domain of CD3 gamma and delta chains; cd07691
Immunoreceptor tyrosine-based activation motif; pfam02189
Ubiquitin fusion degradation protein 2 [Posttranslational modification, protein turnover, chaperones]; COG5113
Ubiquitin elongating factor core; pfam10408
U-box domain; pfam04564
Ubiquitin fusion degradation protein 2 [Posttranslational modification, protein turnover, chaperones]; COG5113
Ubiquitin elongating factor core; pfam10408
U-box domain; pfam04564
Mitochondrial ATP synthase g subunit; pfam04718
CXXC zinc finger domain; pfam02008
PHD-finger; pfam00628
PHD zinc finger; smart00249
PHD-finger; pfam00628
Bromodomain, ALL-1 like proteins. ALL-1 is a vertebrate homologue of Drosophila trithorax and is often affected in chromosomal rearrangements that are linked to acute leukemias, such as acute lymphocytic leukemia (ALL). Bromodomains are found in many...; cd05493
PHD-like zinc-binding domain; pfam13771
PHD zinc finger; smart00249
F/Y-rich N-terminus; pfam05964
FY-rich domain, C-terminal region; smart00542
Proteins containing SET domain [General function prediction only]
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Cysteine-rich motif following a subset of SET domains; smart00508
CXXC zinc finger domain; pfam02008
PHD-finger; pfam00628
PHD zinc finger; smart00249
PHD-finger; pfam00628
Bromodomain, ALL-1 like proteins. ALL-1 is a vertebrate homologue of Drosophila trithorax and is often affected in chromosomal rearrangements that are linked to acute leukemias, such as acute lymphocytic leukemia (ALL). Bromodomains are found in many...; cd05493
PHD-like zinc-binding domain; pfam13771
PHD zinc finger; smart00249
F/Y-rich N-terminus; pfam05964
FY-rich domain, C-terminal region; smart00542
Proteins containing SET domain [General function prediction only]
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Cysteine-rich motif following a subset of SET domains; smart00508
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
CD80-like C2-set immunoglobulin domain; pfam08205
CD80-like C2-set immunoglobulin domain; pfam08205
CD80-like C2-set immunoglobulin domain; pfam08205
CD80-like C2-set immunoglobulin domain; pfam08205
CD80-like C2-set immunoglobulin domain; pfam08205
Intraflagellar transport complex B protein 46 C terminal; pfam12317
Intraflagellar transport complex B protein 46 C terminal; pfam12317
Adaptor complexes medium subunit family; pfam00928
Mu homology domain (MHD) of adaptor protein (AP) coat protein I (COPI) delta subunit; cd09254
Adaptor complexes medium subunit family; pfam00928
Mu homology domain (MHD) of adaptor protein (AP) coat protein I (COPI) delta subunit; cd09254
FHA domain; pfam00498
Valyl tRNA synthetase tRNA binding arm; pfam10458
Pleckstrin homology (PH) domain; cd00821
FHA domain; pfam00498
Valyl tRNA synthetase tRNA binding arm; pfam10458
Pleckstrin homology (PH) domain; cd00821
FHA domain; pfam00498
Valyl tRNA synthetase tRNA binding arm; pfam10458
Pleckstrin homology (PH) domain; cd00821
Neutral trehalase [Carbohydrate transport and metabolism]; COG1626
Trehalase; pfam01204
helicase 45; Provisional
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
helicase 45; Provisional
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
B-cell lymphoma 9 protein; pfam11502
Uroplakin II; cd09967
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
S25 ribosomal protein; pfam03297
Sedlin, N-terminal conserved region; cl02131
Sybindin-like family; pfam04099
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
phosphoglycerate transporter family protein; TIGR00881
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
phosphoglycerate transporter family protein; TIGR00881
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
phosphoglycerate transporter family protein; TIGR00881
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
phosphoglycerate transporter family protein; TIGR00881
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cl17037
this start codon is used for the mRNA originating in exon 2
Hsp70 protein; pfam00012
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cl17037
this start codon is used for the mRNA originating in exon 2
Hsp70 protein; pfam00012
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Region in Clathrin and VPS; pfam00637
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Vacuolar protein sorting protein 11 C terminal; pfam12451
porphobilinogen deaminase; Reviewed; PRK00072
Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; cd00494
porphobilinogen deaminase; Reviewed; PRK00072
Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; cd00494
porphobilinogen deaminase; Reviewed; PRK00072
Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; cd00494
porphobilinogen deaminase; Reviewed; PRK00072
Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; cd00494
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cd00074
UDP-GlcNAc:dolichol-P GlcNAc-1-P transferase (GPT) catalyzes the transfer of GlcNAc-1-P from UDP-GlcNAc to dolichol-P to form GlcNAc-P-P-dolichol. The reaction is the first step in the assembly of dolichol-linked oligosaccharide intermediates and is...; cd06855
UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; COG0472
C2 domain; cl14603
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
The Eye Pigment Precursor Transporter (EPP) Family protein; TIGR00955
ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR).  DR is a well-described phenomenon occurring in fungi and shares several similarities with processes...; cd03213
ABC-2 type transporter; pfam01061
The Eye Pigment Precursor Transporter (EPP) Family protein; TIGR00955
ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR).  DR is a well-described phenomenon occurring in fungi and shares several similarities with processes...; cd03213
ABC-2 type transporter; pfam01061
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
CBL proto-oncogene N-terminal domain 1; pfam02262
CBL proto-oncogene N-terminus, EF hand-like domain; pfam02761
Src homology 2 (SH2) domain found in the Cbl-b TKB domain; cd09920
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
CD80-like C2-set immunoglobulin domain; pfam08205
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
C1q domain; pfam00386
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain; cd07066
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02674
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02674
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02674
Immunoglobulin domain; pfam00047
Immunoglobulin V-Type; smart00406
First immunoglobulin (Ig) domain of nectin-1 (also known as poliovirus receptor related protein 1, or as CD111) and similar proteins; cd05886
Immunoglobulin V-Type; smart00406
Second immunoglobulin (Ig) domain of nectin-1 (also known as poliovirus receptor related protein 1, or as CD111) and similar proteins; cd05890
Immunoglobulin C-2 Type; smart00408
First immunoglobulin (Ig) domain of nectin-1 (also known as poliovirus receptor related protein 1, or as CD111) and similar proteins; cd05886
Immunoglobulin V-Type; smart00406
Second immunoglobulin (Ig) domain of nectin-1 (also known as poliovirus receptor related protein 1, or as CD111) and similar proteins; cd05890
Immunoglobulin C-2 Type; smart00408
First immunoglobulin (Ig) domain of nectin-1 (also known as poliovirus receptor related protein 1, or as CD111) and similar proteins; cd05886
Immunoglobulin V-Type; smart00406
Second immunoglobulin (Ig) domain of nectin-1 (also known as poliovirus receptor related protein 1, or as CD111) and similar proteins; cd05890
Immunoglobulin C-2 Type; smart00408
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
3-oxoacyl-(acyl carrier protein) synthase III; Reviewed
Found in Pit-Oct-Unc transcription factors; smart00352
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Found in Pit-Oct-Unc transcription factors; smart00352
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
TRAM, LAG1 and CLN8 homology domains; smart00724
TLC domain; cl02759
TRAM, LAG1 and CLN8 homology domains; smart00724
TLC domain; cl02759
TRAM, LAG1 and CLN8 homology domains; smart00724
TRAM, LAG1 and CLN8 homology domains; smart00724
TRAM, LAG1 and CLN8 homology domains; smart00724
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Regulator of G protein signaling (RGS) domain found in the leukemia-associated Rho guanine nucleotide exchange factor (RhoGEF) protein (LARG); cd08754
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Regulator of G protein signaling (RGS) domain found in the leukemia-associated Rho guanine nucleotide exchange factor (RhoGEF) protein (LARG); cd08754
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the KA1 and KA2 subunits of Kainate receptor; cd06394
Receptor family ligand binding region; pfam01094
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Bacterial extracellular solute-binding proteins, family 3; pfam00497
Ligand-gated ion channel; pfam00060
Eukaryotic homologues of bacterial periplasmic substrate binding proteins; smart00079
Leucine Rich repeats (2 copies); pfam12799
Ubiquitin-like proteins; cl00155
Leucine Rich repeats (2 copies); pfam12799
Ubiquitin-like proteins; cl00155
Extracellular domain of unknown function in nidogen (entactin) and hypothetical proteins; smart00539
von Willebrand factor type D domain; pfam00094
This domain contains 8 conserved cysteine residues; smart00832
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor type C domain; cl02515
von Willebrand factor (vWF) type D domain; smart00216
C8 domain; pfam08742
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor type D domain; pfam00094
C8 domain; pfam08742
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor type C domain; cl02515
von Willebrand factor (vWF) type D domain; smart00216
C8 domain; pfam08742
Zona pellucida (ZP) domain; smart00241
Sterol desaturase [Lipid metabolism]; COG3000
Fatty acid hydroxylase superfamily; pfam04116
Sterol desaturase [Lipid metabolism]; COG3000
Fatty acid hydroxylase superfamily; pfam04116
VPS10 domain; smart00602
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; smart00060
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
2'-5' RNA ligase superfamily; pfam13563
Src homology 3 domain of Ubiquitin-associated and SH3 domain-containing protein B; cd11936
Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; cd07067
Immunoglobulin V-set domain; pfam07686
First (N-terminal) immunoglobulin (Ig)-like domain of the nectin-like molecules Necl-1 - Necl-3 (also known as cell adhesion molecules CADM3, CADM1, and CADM2 respectively); cd05717
CD80-like C2-set immunoglobulin domain; pfam08205
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Nucleotide-binding domain of HSPA1-A, -B, -L, HSPA-2, -6, -7, -8, and similar proteins; cd10233
heat shock 70 kDa protein; Provisional
Nucleotide-binding domain of HSPA1-A, -B, -L, HSPA-2, -6, -7, -8, and similar proteins; cd10233
Immunoglobulin domain; cl11960
Immunoglobulin V-Type; smart00406
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
domain in glucosyltransferases, myotubularins and other putative membrane-associated proteins; smart00568
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
SCAN oligomerization domain; cd07936
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
PMP-22/EMP/MP20/Claudin tight junction; pfam13903
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Vault protein Inter-alpha-Trypsin domain; smart00609
marine proteobacterial sortase target protein; TIGR03788
vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to...; cd01461
Vault protein Inter-alpha-Trypsin domain; smart00609
marine proteobacterial sortase target protein; TIGR03788
vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to...; cd01461
Vault protein Inter-alpha-Trypsin domain; smart00609
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
F/Y-rich N-terminus; pfam05964
F/Y rich C-terminus; pfam05965
Domain of unknown function (DUF303); pfam03629
Domain of unknown function (DUF303); pfam03629
Dimerization/Docking domain of the sperm fibrous sheath proteins, Calcium-Binding tYrosine-phosphorylation Regulated protein and Sperm Protein 17; cd12100
IQ calmodulin-binding motif; cl15479
IQ calmodulin-binding motif; cl15479
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Myb/SANT-like DNA-binding domain; pfam13837
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; cd05726
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Second immunoglobulin (Ig)-like domain in Robo (roundabout) receptors; cd05724
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Sugar phosphate permease [Carbohydrate transport and metabolism]; COG2271
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Sugar phosphate permease [Carbohydrate transport and metabolism]; COG2271
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
FEZ-like protein; pfam07763
FEZ-like protein; pfam07763
Etoposide-induced protein 2.4 (EI24); pfam07264
Etoposide-induced protein 2.4 (EI24); pfam07264
Oligosaccharyl transferase STT3 subunit; pfam02516
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
Pseudouridylate synthase [Translation, ribosomal structure and biogenesis]; COG0101
Pseudouridine synthase, Saccharomyces cerevisiae Pus3 like; cd02569
helicase 45; Provisional
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; COG1187
Pseudouridine synthase, RsuA/RluD family; cd02869
Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; COG0564
Pseudouridine synthase, RsuA/RluD family; cd02869
SIR2-like domain; pfam13289
Signal recognition particle, alpha subunit, N-terminal; pfam04086
SRP54-type protein, helical bundle domain; smart00963
SRP54-type protein, GTPase domain; smart00962
The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; cd03115
Signal recognition particle, alpha subunit, N-terminal; pfam04086
SRP54-type protein, helical bundle domain; smart00963
SRP54-type protein, GTPase domain; smart00962
The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; cd03115
Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; COG0665
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
TIR domain; pfam13676
TIR domain; pfam13676
Scavenger mRNA decapping enzyme (DcpS) N-terminal; pfam05652
Uncharacterized conserved protein [Function unknown]
Scavenger mRNA decapping enzyme C-term binding; pfam11969
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2); cd05759
Immunoglobulin domain; pfam13895
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein (also known as Neph2); cd05898
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2); cd05759
Immunoglobulin domain; pfam13895
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein (also known as Neph2); cd05898
Sterile alpha motif (SAM)/Pointed domain of ETS-1; cd08542
Ets-domain; pfam00178
Ets-domain; pfam00178
Sterile alpha motif (SAM)/Pointed domain of ETS-1; cd08542
Ets-domain; pfam00178
Sterile alpha motif (SAM)/Pointed domain of friend leukemia integration 1 transcription activator; cd08541
Ets-domain; pfam00178
Sterile alpha motif (SAM)/Pointed domain of friend leukemia integration 1 transcription activator; cd08541
Ets-domain; pfam00178
Ets-domain; pfam00178
Sterile alpha motif (SAM)/Pointed domain of friend leukemia integration 1 transcription activator; cd08541
Ets-domain; pfam00178
Inward rectifier potassium channel; pfam01007
Inward rectifier potassium channel; pfam01007
Inward rectifier potassium channel; pfam01007
Inward rectifier potassium channel; pfam01007
Inward rectifier potassium channel; pfam01007
Inward rectifier potassium channel; pfam01007
Ion transport protein; pfam00520
The phosphoinositide binding Phox Homology domain of PX-RICS; cd07298
Src homology 3 domain of Rho GTPase-activating proteins 32 and 33, and similar proteins; cd11835
RhoGAP_CdGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP...; cd04384
GTPase-activator protein for Rho-like GTPases; smart00324
RhoGAP_CdGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP...; cd04384
GTPase-activator protein for Rho-like GTPases; smart00324
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Translocation protein Sec62; cl02170
Family of unknown function (DUF716); pfam04819
NFRKB Winged Helix-like; pfam14465
NFRKB Winged Helix-like; pfam14465
SET domain; pfam00856
Zinc finger, C2H2 type; cl15478
SET domain; pfam00856
Zinc finger, C2H2 type; cl15478
SET domain; pfam00856
Zinc-finger double-stranded RNA-binding; cl09952
Zinc finger, C2H2 type; cl15478
SET domain; pfam00856
Zinc-finger double-stranded RNA-binding; cl09952
Zinc finger, C2H2 type; cl15478
amyloid A4; smart00006
Amyloid A4 N-terminal heparin-binding; pfam02177
Copper-binding of amyloid precursor, CuBD; pfam12924
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
E2 domain of amyloid precursor protein; pfam12925
beta-amyloid precursor protein C-terminus; pfam10515
amyloid A4; smart00006
Amyloid A4 N-terminal heparin-binding; pfam02177
Copper-binding of amyloid precursor, CuBD; pfam12924
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
E2 domain of amyloid precursor protein; pfam12925
beta-amyloid precursor protein C-terminus; pfam10515
amyloid A4; smart00006
Amyloid A4 N-terminal heparin-binding; pfam02177
Copper-binding of amyloid precursor, CuBD; pfam12924
E2 domain of amyloid precursor protein; pfam12925
beta-amyloid precursor protein C-terminus; pfam10515
Amyloid A4 N-terminal heparin-binding; pfam02177
E2 domain of amyloid precursor protein; pfam12925
beta-amyloid precursor protein C-terminus; pfam10515
amyloid A4; smart00006
Amyloid A4 N-terminal heparin-binding; pfam02177
Copper-binding of amyloid precursor, CuBD; pfam12924
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
E2 domain of amyloid precursor protein; pfam12925
beta-amyloid precursor protein C-terminus; pfam10515
SEA domain; pfam01390
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
BTB/POZ domain; pfam00651
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that...; cd04273
ADAM cysteine-rich; cl15456
Thrombospondin type 1 repeats; smart00209
ADAM-TS Spacer 1; pfam05986
Thrombospondin type 1 repeats; smart00209
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that...; cd04273
ADAM cysteine-rich; cl15456
Thrombospondin type 1 repeats; smart00209
ADAM-TS Spacer 1; pfam05986
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Domain associated with PX domains; smart00313
The phosphoinositide binding Phox Homology domain of Sorting Nexin 19; cd06893
Sorting nexin C terminal; pfam08628
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin C-2 Type; smart00408
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin C-2 Type; smart00408
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin C-2 Type; smart00408
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin C-2 Type; smart00408
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
non-SMC mitotic condensation complex subunit 1; pfam12717
Vacuolar protein sorting-associated protein 26; pfam03643
EVE domain; pfam01878
EVE domain; pfam01878
EVE domain; pfam01878
EVE domain; pfam01878
EVE domain; pfam01878
Acyl-CoA dehydrogenases [Lipid metabolism]; COG1960
Isobutyryl-CoA dehydrogenase; cd01162
Glycosyl hydrolases family 35; pfam01301
Glycosyl hydrolases family 2, sugar binding domain; cl08371
Glycosyl hydrolases family 35; pfam01301
Beta1,3-glucuronyltransferase I (GlcAT-I) is involved in the initial steps of proteoglycan synthesis; cd00218
Beta1,3-glucuronyltransferase I (GlcAT-I) is involved in the initial steps of proteoglycan synthesis; cd00218
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor...; cd00171
Pleckstrin homology (PH) domain; cd00821
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor...; cd00171
Pleckstrin homology (PH) domain; cd00821
Na(+)- and Cl(-)-dependent betaine/GABA transporter-1, and related proteins; solute-binding domain; cd11511
Na(+)- and Cl(-)-dependent betaine/GABA transporter-1, and related proteins; solute-binding domain; cd11511
Na(+)- and Cl(-)-dependent betaine/GABA transporter-1, and related proteins; solute-binding domain; cd11511
Na(+)- and Cl(-)-dependent betaine/GABA transporter-1, and related proteins; solute-binding domain; cd11511
Solute carrier families 5 and 6-like; solute binding domain; cl00456
Solute carrier families 5 and 6-like; solute binding domain; cl00456
Na(+)- and Cl(-)-dependent GABA transporter 2; solute-binding domain; cd11507
Solute carrier families 5 and 6-like; solute binding domain; cl00456
Small domain found in the jumonji family of transcription factors; smart00545
ARID/BRIGHT DNA binding domain; pfam01388
PHD-finger; pfam00628
JmjC domain, hydroxylase; pfam02373
C5HC2 zinc finger; pfam02928
PLU-1-like protein; pfam08429
PHD zinc finger; smart00249
PHD-finger; pfam00628
chromosome segregation protein SMC, common bacterial type; TIGR02168
chromosome segregation protein SMC, common bacterial type; TIGR02168
chromosome segregation protein SMC, common bacterial type; TIGR02168
chromosome segregation protein SMC, common bacterial type; TIGR02168
PA14 domain; pfam07691
N-terminal domain of galactosyltransferase; pfam02709
Ninjurin; pfam04923
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Oxidative-stress-responsive kinase 1 C terminal; pfam12202
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Oxidative-stress-responsive kinase 1 C terminal; pfam12202
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Oxidative-stress-responsive kinase 1 C terminal; pfam12202
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Oxidative-stress-responsive kinase 1 C terminal; pfam12202
recombination protein rad52; TIGR00607
RIM-binding protein of the cytomatrix active zone; pfam10174
FIP domain; pfam09457
RIM-binding protein of the cytomatrix active zone; pfam10174
FIP domain; pfam09457
F-box-like; pfam12937
Antagonist of mitotic exit network protein 1; cl15308
Antagonist of mitotic exit network protein 1; cl15308
wnt family; pfam00110
found in Wnt-1; smart00097
wnt family; pfam00110
found in Wnt-1; smart00097
Haemolysin-III related; pfam03006
VWA N-terminal; pfam08399
VWA Voltage gated Calcium channel like: Voltage-gated calcium channels are a complex of five proteins: alpha 1, beta 1, gamma, alpha 2 and delta. The alpha 2 and delta subunits result from proteolytic processing of a single gene product and carries at...; cd01463
Cache domain; pfam02743
Leucine rich repeat N-terminal domain; pfam01462
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat N-terminal domain; pfam01462
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat N-terminal domain; pfam01462
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
mRNA decapping enzyme 1 (Dcp1); cd09804
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
FKBP-type peptidyl-prolyl cis-trans isomerase; pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase; pfam00254
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13432
TPR repeat; pfam13414
FG-GAP repeat; pfam01839
NRIP_C; putative nuclear receptor interacting protein; cd05480
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
Tub family; pfam01167
Tub family; pfam01167
TEA/ATTS domain family; pfam01285
TEA/ATTS domain family; pfam01285
TEA/ATTS domain family; pfam01285
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model...; cd03165
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), NET-5_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model...; cd03165
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13833
Rab family protein; Provisional
Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases); cd00154
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13833
Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis; smart00678
Poly(ADP-ribose) polymerases catalyse the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a regulatory component...; cd01439
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Cyclin, C-terminal domain; pfam02984
Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; cd07067
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
Uncharacterized conserved protein (DUF2362); pfam10154
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
A-kinase anchor protein 110 kDa; smart00807
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, subunit 9, 39 kDa, (NDUFA9) -like, atypical (a) SDRs; cd05271
NAD dependent epimerase/dehydratase family; pfam01370
Predicted glycosyltransferases [General function prediction only]
pp-GalNAc-T initiates the formation of mucin-type O-linked glycans; cd02510
Ricin-type beta-trefoil lectin domain; pfam00652
Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; cd00161
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
Nerve growth factor family; pfam00243
Nerve growth factor family; pfam00243
Calcium-activated chloride channel; pfam04547
von Willebrand factor (vWF) type D domain; smart00216
This domain contains 8 conserved cysteine residues; smart00832
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor type C domain; cl02515
von Willebrand factor (vWF) type D domain; smart00216
C8 domain; pfam08742
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor (vWF) type D domain; smart00216
This domain contains 8 conserved cysteine residues; smart00832
Trypsin Inhibitor like cysteine rich domain; pfam01826
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cd01450
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cd01450
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cd01450
von Willebrand factor (vWF) type D domain; smart00216
C8 domain; pfam08742
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor type C domain; pfam00093
von Willebrand factor type C domain; pfam00093
von Willebrand factor type C domain; pfam00093
C-terminal cystine knot-like domain (CTCK); smart00041
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), CD9 family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans...; cd03152
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cd00900
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cd00900
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cd00900
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Death domain of Tumor Necrosis Factor Receptor 1; cd08313
sodium channel transporter; TIGR00859
sodium channel transporter; TIGR00859
sodium channel transporter; TIGR00859
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cl12111
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cl12111
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Immunoglobulin domain; cd00096
Tapasin-R immunoglobulin-like domain; cd05771
Synaptobrevin; pfam00957
Synaptobrevin; pfam00957
Synaptobrevin; pfam00957
Mitochondrial ribosomal subunit; pfam10244
non-SMC mitotic condensation complex subunit 1, N-term; pfam12922
non-SMC mitotic condensation complex subunit 1; pfam12717
glyceraldehyde-3-phosphate dehydrogenase; Provisional
Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; smart00846
Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; pfam02800
Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; pfam00044
Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; pfam02800
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
NOL1/NOP2/sun family; pfam01189
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
NOL1/NOP2/sun family; pfam01189
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
NOL1/NOP2/sun family; pfam01189
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Putative binding domain; pfam13900
NOL1/NOP2/sun family; pfam01189
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
NOL1/NOP2/sun family; pfam01189
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
CHDNT (NUC034) domain; pfam08073
PHD-finger; pfam00628
PHD-finger; pfam00628
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Domain of Unknown Function (DUF1087); pfam06465
Domain of Unknown Function (DUF1086); pfam06461
CHDCT2 (NUC038) domain; pfam08074
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
Proacrosin binding protein sp32; pfam07222
Inhibitor of growth proteins N-terminal histone-binding; pfam12998
PHD-finger; pfam00628
Inhibitor of growth proteins N-terminal histone-binding; pfam12998
Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]; COG5034
PHD-finger; pfam00628
Inhibitor of growth proteins N-terminal histone-binding; pfam12998
Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]; COG5034
PHD-finger; pfam00628
Inhibitor of growth proteins N-terminal histone-binding; pfam12998
Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]; COG5034
PHD-finger; pfam00628
Inhibitor of growth proteins N-terminal histone-binding; pfam12998
Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]; COG5034
PHD-finger; pfam00628
Inhibitor of growth proteins N-terminal histone-binding; pfam12998
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
PCI domain; pfam01399
PCI domain; pfam01399
PCI domain; pfam01399
PCI domain; pfam01399
Myelodysplasia-myeloid leukemia factor 1-interacting protein; pfam10248
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
First immunoglobulin (Ig) domain of CD4; cd07690
Immunoglobulin V-Type; smart00406
Second immunoglobulin (Ig) domain of CD4; cd07694
Third immunoglobulin (Ig) domain of CD4; cd07695
Immunoglobulin C2-set domain; pfam05790
T cell CD4 receptor C terminal region; pfam12104
Third immunoglobulin (Ig) domain of CD4; cd07695
Immunoglobulin C2-set domain; pfam05790
T cell CD4 receptor C terminal region; pfam12104
Immunoglobulin domain; cl11960
Immunoglobulin C2-set domain; pfam05790
T cell CD4 receptor C terminal region; pfam12104
Immunoglobulin domain; cl11960
Immunoglobulin C2-set domain; pfam05790
T cell CD4 receptor C terminal region; pfam12104
Immunoglobulin domain; cl11960
Immunoglobulin C2-set domain; pfam05790
T cell CD4 receptor C terminal region; pfam12104
7 transmembrane receptor (rhodopsin family); pfam00001
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam13640
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Isopeptidase T [Posttranslational modification, protein turnover, chaperones]; COG5207
Zn-finger in ubiquitin-hydrolases and other protein; pfam02148
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02658
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Isopeptidase T [Posttranslational modification, protein turnover, chaperones]; COG5207
Zn-finger in ubiquitin-hydrolases and other protein; pfam02148
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02658
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; cd00311
triosephosphate isomerase; Provisional
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; cd00311
triosephosphate isomerase; Provisional
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; cd00311
Domain in SPla and the RYanodine Receptor; smart00449
SOCS (suppressors of cytokine signaling) box of SSB2 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB2 has been shown to bind to MET, the receptor protein-tyrosine kinase for...; cd03719
Domain in SPla and the RYanodine Receptor; smart00449
SOCS (suppressors of cytokine signaling) box of SSB2 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB2 has been shown to bind to MET, the receptor protein-tyrosine kinase for...; cd03719
Leucine Rich repeats (2 copies); pfam12799
Leucine Rich repeats (2 copies); pfam12799
Leucine Rich repeats (2 copies); pfam12799
Leucine Rich repeats (2 copies); pfam12799
Leucine Rich repeats (2 copies); pfam12799
Leucine Rich repeats (2 copies); pfam12799
enolase
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; cd03313
Atrophin-1 family; pfam03154
19Q repeat
Atrophin-1 family; pfam03154
Atrophin-1 family; pfam03154
19Q repeat
Atrophin-1 family; pfam03154
N-terminal Src homology 2 (N-SH2) domain found in SH2 domain Phosphatases (SHP) proteins; cd10340
C-terminal Src homology 2 (C-SH2) domain found in SH2 domain Phosphatases (SHP) proteins; cd09931
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
N-terminal Src homology 2 (N-SH2) domain found in SH2 domain Phosphatases (SHP) proteins; cd10340
C-terminal Src homology 2 (C-SH2) domain found in SH2 domain Phosphatases (SHP) proteins; cd09931
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
N-terminal Src homology 2 (N-SH2) domain found in SH2 domain Phosphatases (SHP) proteins; cd10340
C-terminal Src homology 2 (C-SH2) domain found in SH2 domain Phosphatases (SHP) proteins; cd09931
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; COG0330
Band_7_prohibitin. A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup group includes proteins similar to prohibitin (a lipid raft-associated integral membrane protein).  Individual proteins of this band 7 domain family may...; cd03401
HflC protein; TIGR01932
Band_7_prohibitin. A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup group includes proteins similar to prohibitin (a lipid raft-associated integral membrane protein).  Individual proteins of this band 7 domain family may...; cd03401
EMG1/NEP1 methyltransferase; pfam03587
MBOAT, membrane-bound O-acyltransferase family; cl00738
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13432
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13432
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13432
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13432
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13432
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; COG0365
AMP-binding enzyme; pfam00501
Domain of unknown function (DUF4009); pfam13193
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
APOBEC-like N-terminal domain; pfam08210
Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; cd01283
APOBEC-like C-terminal domain; pfam05240
TGF-beta propeptide; pfam00688
Transforming growth factor-beta (TGF-beta) family; smart00204
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Sugar (and other) transporter; pfam00083
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Sugar (and other) transporter; pfam00083
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
7 transmembrane receptor (rhodopsin family); pfam00001
Protein of unknown function (DUF1681); pfam07933
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
large tegument protein UL36; Provisional
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; cd01283
APOBEC-like N-terminal domain; pfam08210
APOBEC-like C-terminal domain; pfam05240
Microfibril-associated glycoprotein (MAGP); pfam05507
alpha-L-glutamate ligases, RimK family; TIGR00768
ATP-grasp domain; cl03087
MG2 domain; pfam01835
Alpha-2-macroglobulin family N-terminal region; pfam07703
Alpha-2-macroglobulin family; pfam00207
Proteins similar to alpha2-macroglobulin (alpha (2)-M). This group also contains the pregnancy zone protein (PZP).  Alpha(2)-M and PZP are broadly specific proteinase inhibitors. Alpha (2)-M is a major carrier protein in serum. The structural thioester...; cd02897
A-macroglobulin complement component; pfam07678
A-macroglobulin receptor; pfam07677
MYM-type Zinc finger with FCS sequence motif; pfam06467
SAM domain of Ph (polyhomeotic) proteins of Polycomb group; cd09577
Sterile alpha motif; smart00454
Mannose-6-phosphate receptor; pfam02157
Mannose-6-phosphate receptor; pfam02157
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
Alpha-2-macroglobulin MG1 domain; pfam11974
MG2 domain; pfam01835
Alpha-2-macroglobulin family N-terminal region; pfam07703
Alpha-2-macroglobulin family N-terminal region; pfam07703
Alpha-2-macroglobulin family; pfam00207
Proteins similar to alpha2-macroglobulin (alpha (2)-M). This group also contains the pregnancy zone protein (PZP).  Alpha(2)-M and PZP are broadly specific proteinase inhibitors. Alpha (2)-M is a major carrier protein in serum. The structural thioester...; cd02897
A-macroglobulin complement component; pfam07678
A-macroglobulin receptor; pfam07677
Alpha-2-macroglobulin MG1 domain; pfam11974
MG2 domain; pfam01835
Alpha-2-macroglobulin family N-terminal region; pfam07703
Alpha-2-macroglobulin family; pfam00207
Seminal vesicle autoantigen (SVA); pfam05326
Proteins similar to alpha2-macroglobulin (alpha (2)-M). This group also contains the pregnancy zone protein (PZP).  Alpha(2)-M and PZP are broadly specific proteinase inhibitors. Alpha (2)-M is a major carrier protein in serum. The structural thioester...; cd02897
A-macroglobulin complement component; pfam07678
A-macroglobulin receptor; pfam07677
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like protein; Provisional
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
Ubiquitin domain of GABA-receptor-associated protein; cd01611
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like protein; Provisional
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like protein; Provisional
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; cl06868
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs); cd03593
Mago nashi proteins, integral members of the exon junction complex; cd11295
Protein tyrosine kinase; pfam07714
Catalytic domain of Protein Tyrosine Kinases; cd00192
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Mammalian taste receptor protein (TAS2R); pfam05296
Mammalian taste receptor protein (TAS2R); pfam05296
Mammalian taste receptor protein (TAS2R); pfam05296
Mammalian taste receptor protein (TAS2R); pfam05296
Mammalian taste receptor protein (TAS2R); pfam05296
Mammalian taste receptor protein (TAS2R); pfam05296
Vomeronasal organ pheromone receptor family, V1R; cl12106
Mammalian taste receptor protein (TAS2R); pfam05296
Mammalian taste receptor protein (TAS2R); pfam05296
Mammalian taste receptor protein (TAS2R); pfam05296
Mammalian taste receptor protein (TAS2R); pfam05296
Mammalian taste receptor protein (TAS2R); pfam05296
Mammalian taste receptor protein (TAS2R); pfam05296
Vomeronasal organ pheromone receptor family, V1R; cl12106
Sterile alpha motif (SAM)/Pointed domain of Tel/Yan protein; cd08535
Ets-domain; pfam00178
Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane...; cl02575
Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane...; cl02575
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; cl10508
Low-density lipoprotein receptor repeat class B; cl10508
Low-density lipoprotein-receptor YWTD domain; smart00135
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
The MANEC domain, formerly called MANSC; smart00765
Tumour suppressor protein; pfam10158
N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by...; cd01446
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
Basic region leucine zipper; pfam07716
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Cyclin-dependent kinase inhibitor; pfam02234
ATP-dependent RNA helicase SrmB; Provisional
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
ATP-dependent RNA helicase SrmB; Provisional
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
7 transmembrane sweet-taste receptor of 3 GCPR; pfam00003
7 transmembrane sweet-taste receptor of 3 GCPR; pfam00003
SOUL heme-binding protein; pfam04832
GSG1-like protein; pfam07803
GSG1-like protein; pfam07803
GSG1-like protein; pfam07803
GSG1-like protein; pfam07803
GSG1-like protein; pfam07803
GSG1-like protein; pfam07803
GSG1-like protein; pfam07803
PMP-22/EMP/MP20/Claudin family; pfam00822
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family; cd06378
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Ligand-gated ion channel; pfam00060
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
N-methyl D-aspartate receptor 2B3 C-terminus; pfam10565
AAA ATPase containing von Willebrand factor type A (vWA) domain [General function prediction only]; COG5271
Phospholipase B; pfam04916
Ligand-binding domain of the membrane guanylyl cyclase C; cd06369
Receptor family ligand binding region; pfam01094
Protein kinase; unclassified specificity; smart00221
Protein Kinases, catalytic domain; cl09925
Adenylyl- / guanylyl cyclase, catalytic domain; smart00044
cyclase homology domain; cd07302
Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into 'beads on a string' in...; cd00076
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cd00074
WW domain binding protein 11; pfam09429
VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of...; cl00173
Domain containing Gla (gamma-carboxyglutamate) residues; smart00069
Domain containing Gla (gamma-carboxyglutamate) residues; smart00069
Protein Disulfide Isomerase (PDIb) family, redox inactive TRX-like domain b; composed of eukaryotic proteins involved in oxidative protein folding in the endoplasmic reticulum (ER) by acting as catalysts and folding assistants. Members of this family...; cd02981
Thioredoxin-like domain; pfam13848
Protein Disulfide Isomerase (PDIb') family, redox inactive TRX-like domain b'; composed of eukaryotic proteins involved in oxidative protein folding in the endoplasmic reticulum (ER) by acting as catalysts and folding assistants. Members of this family...; cd02982
RHO protein GDP dissociation inhibitor; pfam02115
Retinal cGMP phosphodiesterase, gamma subunit; pfam04868
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Ras-related and Estrogen-Regulated Growth inhibitor (RERG) and Ras-like 11 (RasL11)-like families; cd04146
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Phosphotyrosine-binding domain; pfam08416
Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins; cd11764
SAM domain of EPS8-like subfamily; cd09540
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; cd00959
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cl11420
MAPEG family; pfam01124
MAPEG family; pfam01124
MAPEG family; pfam01124
MAPEG family; pfam01124
MAPEG family; pfam01124
The first LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3); cd09388
The second LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3); cd09389
The first LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3); cd09388
The second LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3); cd09389
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
The second LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3); cd09389
The first LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3); cd09388
The second LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3); cd09389
The first LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3); cd09388
The second LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3); cd09389
The first LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3); cd09388
The second LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3); cd09389
The first LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3); cd09388
The second LIM domain of LMO1 and LMO3 (LIM domain only protein 1 and 3); cd09389
Ras-related and Estrogen-Regulated Growth inhibitor (RERG) and Ras-like 11 (RasL11)-like families; cd04146
PI3-kinase family, ras-binding domain; cl02484
Phosphoinositide 3-kinase C2; pfam00792
Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general,  class II PI3-kinases...; cd00869
Phosphoinositide 3-kinase (PI3K), class II, gamma isoform, catalytic domain; The PI3K catalytic domain family is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein...; cd05177
Phosphoinositide 3-kinase, catalytic domain; smart00146
The phosphoinositide binding Phox Homology Domain of the Gamma Isoform of Class II Phosphoinositide 3-Kinases; cd06896
C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks); cd08381
phosphoinositide phospholipase C
Phosphoinositide-specific phospholipase C, efhand-like; pfam09279
Catalytic domain of metazoan phosphoinositide-specific phospholipase C-zeta; cd08595
C2 domain present in Phosphoinositide-specific phospholipases C (PLC); cd00275
F-actin capping protein alpha subunit; pfam01267
WW domain; pfam00397
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Pleckstrin homology (PH) domain; cd00821
WW domain; pfam00397
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Pleckstrin homology (PH) domain; cd00821
WW domain; pfam00397
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Pleckstrin homology (PH) domain; cd00821
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cl00157
Pleckstrin homology (PH) domain; cd00821
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; cl00454
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Organic Anion Transporter Polypeptide (OATP) family; pfam03137
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a...; cd01330
Organic Anion Transporter Polypeptide (OATP) family; pfam03137
The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a...; cd01330
Organic Anion Transporter Polypeptide (OATP) family; pfam03137
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a...; cd01330
Organic Anion Transporter Polypeptide (OATP) family; pfam03137
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a...; cd01330
Organic Anion Transporter Polypeptide (OATP) family; pfam03137
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a...; cd01330
Organic Anion Transporter Polypeptide (OATP) family; pfam03137
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a...; cd01330
Organic Anion Transporter Polypeptide (OATP) family; pfam03137
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a...; cd01330
sodium-independent organic anion transporter; TIGR00805
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a...; cd01330
sodium-independent organic anion transporter; TIGR00805
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a...; cd01330
Calcitonin / CGRP / IAPP family; pfam00214
calcitonin; smart00113
Pyridine nucleotide-disulphide oxidoreductase; pfam07992
ATP-dependent DNA helicase, RecQ family; TIGR00614
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
RQC domain; cl09632
ATP-dependent DNA helicase, RecQ family; TIGR00614
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
RQC domain; cl09632
Got1/Sft2-like family; cl02130
Glycogen synthase; pfam05693
Glycogen synthase, which is most closely related to the GT1 family of glycosyltransferases, catalyzes the transfer of a glucose molecule from UDP-glucose to a terminal branch of a glycogen molecule, a rate-limit step of glycogen biosynthesis. GSY2, the...; cd03793
A subgroup of L-lactate dehydrogenases; cd05293
L-lactate dehydrogenase; TIGR01771
A subgroup of L-lactate dehydrogenases; cd05293
L-lactate dehydrogenase; TIGR01771
Inward rectifier potassium channel; pfam01007
ABC transporter transmembrane region; cl00549
ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; COG1122
The SUR domain 1.  The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains.  Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the...; cd03290
ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; COG1132
ABC transporter transmembrane region; cl00549
The SUR domain 2.  The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family.  Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel...; cd03288
ABC transporter transmembrane region; cl00549
ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; COG1122
The SUR domain 1.  The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains.  Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the...; cd03290
ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; COG1132
ABC transporter transmembrane region; cl00549
The SUR domain 2.  The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family.  Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel...; cd03288
CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; cd02513
Haloacid Dehalogenase-like Hydrolases; cl11391
Glycosyltransferase family 29 (sialyltransferase); pfam00777
C2 domain found in the Human KIAA0528 cDNA clone; cd08688
Ethanolamine kinase (ETNK) in eukaryotes. ETNK is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and...; cd05157
Phosphotransferase enzyme family; pfam01636
Protein Kinases, catalytic domain; cl09925
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]; COG5648
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
branched-chain amino acid aminotransferase; Provisional
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; cd01557
branched-chain amino acid aminotransferase; Provisional
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; cd01557
branched-chain amino acid aminotransferase; Provisional
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; cd01557
branched-chain amino acid aminotransferase; Provisional
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; cd01557
branched-chain amino acid aminotransferase; Provisional
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; cd01557
MRVI1 protein; pfam05781
MRVI1 protein; pfam05781
MRVI1 protein; pfam05781
Cancer susceptibility candidate 1; pfam12366
Cancer susceptibility candidate 1; pfam12366
Cancer susceptibility candidate 1; pfam12366
Cancer susceptibility candidate 1; pfam12366
Cancer susceptibility candidate 1; pfam12366
Cancer susceptibility candidate 1; pfam12366
Cancer susceptibility candidate 1; pfam12366
Cancer susceptibility candidate 1; pfam12366
Cancer susceptibility candidate 1; pfam12366
Cancer susceptibility candidate 1; pfam12366
Complex1_LYR-like; pfam13232
Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B; cd04138
GTPase SAR1 and related small G proteins [General function prediction only]
Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B; cd04138
Lamin Tail Domain; pfam00932
Lamin Tail Domain; pfam00932
Lamin Tail Domain; pfam00932
Lamin Tail Domain; pfam00932
Lamin Tail Domain; pfam00932
Ras association (RalGDS/AF-6) domain; smart00314
Ras association (RalGDS/AF-6) domain; smart00314
Ras association (RalGDS/AF-6) domain; smart00314
Ras association (RalGDS/AF-6) domain; smart00314
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Hairy Orange; pfam07527
CD20-like family; pfam04103
CD20-like family; pfam04103
Inositol 1,4,5-trisphosphate/ryanodine receptor; pfam08709
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
MIR domain; pfam02815
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
RIH domain; pfam01365
RIH domain; pfam01365
RyR and IP3R Homology associated; pfam08454
Protein of unknown function (DUF3792); pfam12670
Cell cycle and development regulator; pfam10221
Protein of unknown function (DUF837); pfam05769
Protein of unknown function (DUF837); pfam05769
Protein of unknown function (DUF837); pfam05769
Domain of unknown function (DUF4203); pfam13886
Subunit 21 of Mediator complex; pfam11221
Catalytic domain of the Protein Serine/Threonine Kinase, Nuclear Dbf2-Related kinase 2; cd05627
Serine/Threonine protein kinases, catalytic domain; smart00220
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Sterile alpha motif; smart00454
SAM domain of liprin-beta1,2 proteins repeat 1; cd09563
SAM (Sterile alpha motif ); cl15755
Sterile alpha motif; smart00454
SAM domain of liprin-beta proteins repeat 3; cd09569
SAM domain (Sterile alpha motif); pfam07647
Sterile alpha motif; smart00454
SAM domain of liprin-beta1,2 proteins repeat 1; cd09563
SAM (Sterile alpha motif ); cl15755
Sterile alpha motif; smart00454
SAM domain of liprin-beta proteins repeat 3; cd09569
SAM domain (Sterile alpha motif); pfam07647
Sterile alpha motif; smart00454
SAM domain of liprin-beta1,2 proteins repeat 1; cd09563
SAM (Sterile alpha motif ); cl15755
Sterile alpha motif; smart00454
SAM domain of liprin-beta proteins repeat 3; cd09569
SAM domain (Sterile alpha motif); pfam07647
Sterile alpha motif; smart00454
SAM domain of liprin-beta1,2 proteins repeat 1; cd09563
SAM (Sterile alpha motif ); cl15755
Sterile alpha motif; smart00454
SAM domain of liprin-beta proteins repeat 3; cd09569
SAM domain (Sterile alpha motif); pfam07647
Mitochondrial ribosomal subunit protein; pfam10213
The MANEC domain, formerly called MANSC; smart00765
BTB/POZ domain; cl02518
BTB And C-terminal Kelch; smart00875
Kelch domain; smart00612
Kelch domain; smart00612
Parathyroid hormone family; pfam01279
Parathyroid hormone family; pfam01279
Parathyroid hormone family; pfam01279
Parathyroid hormone family; pfam01279
chromosome segregation protein SMC, common bacterial type; TIGR02168
fatty acyl-CoA reductase
fatty acyl CoA reductases (FARs), extended (e) SDRs; cd05236
C-terminal domain of fatty acyl CoA reductases; cd09071
Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC); pfam13850
Endoplasmic reticulum vesicle transporter; pfam07970
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cl00049
Domain of unknown function (DUF1736); pfam08409
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Domain of unknown function (DUF1736); pfam08409
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Importin, protein involved in nuclear import [Posttranslational modification, protein turnover, chaperones]; COG5656
Importin-beta N-terminal domain; pfam03810
Importin, protein involved in nuclear import [Posttranslational modification, protein turnover, chaperones]; COG5656
Cytoplasmic activation/proliferation-associated protein-1 C term; pfam12287
C1q domain; pfam00386
Cytoplasmic activation/proliferation-associated protein-1 C term; pfam12287
C1q domain; pfam00386
Cytoplasmic activation/proliferation-associated protein-1 C term; pfam12287
Cytoplasmic activation/proliferation-associated protein-1 C term; pfam12287
Tetraspanin family; pfam00335
envelope glycoprotein M; Provisional
Tetraspanin, extracellular domain or large extracellular loop (LEL), CD151_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model...; cd03155
DNA repair helicase (rad3); TIGR00604
DEAD_2; pfam06733
helicase superfamily c-terminal domain; smart00491
DNA repair helicase (rad3); TIGR00604
DEAD_2; pfam06733
helicase superfamily c-terminal domain; smart00491
DNA repair helicase (rad3); TIGR00604
DEAD_2; pfam06733
helicase superfamily c-terminal domain; smart00491
DNA repair helicase (rad3); TIGR00604
DEAD_2; pfam06733
helicase superfamily c-terminal domain; smart00491
DNA repair helicase (rad3); TIGR00604
DEAD_2; pfam06733
helicase superfamily c-terminal domain; smart00491
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
DENN (AEX-3) domain; pfam02141
dDENN domain; pfam03455
RUN domain; cl02689
PLAT/LH2 domain present in RAB6 interacting protein 1 (Rab6IP1)_like family. PLAT/LH2 domains consists of an eight stranded beta-barrel. In RabIP1 this domain may participate in lipid-mediated modulation of Rab6IP1's function via it's generally proposed...; cd01757
RUN domain; cl02689
Predicted methyltransferase [General function prediction only]
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Predicted methyltransferase [General function prediction only]
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Predicted methyltransferase [General function prediction only]
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Antagonist of mitotic exit network protein 1; cd09293
histone H3; Provisional
Microtubule-associated protein Bicaudal-D; pfam09730
Microtubule-associated protein Bicaudal-D; pfam09730
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
FYVE zinc finger; pfam01363
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Pleckstrin homology (PH) domain; cd00821
Dynamin_like protein family includes dynamins and Mx proteins; cd08771
Dynamin family; pfam00350
Predicted GTPases (dynamin-related) [General function prediction only]
Dynamin central region; pfam01031
Dynamin GTPase effector domain; pfam02212
Dynamin_like protein family includes dynamins and Mx proteins; cd08771
Dynamin family; pfam00350
Predicted GTPases (dynamin-related) [General function prediction only]
Dynamin central region; pfam01031
Dynamin GTPase effector domain; pfam02212
Dynamin_like protein family includes dynamins and Mx proteins; cd08771
Dynamin family; pfam00350
Predicted GTPases (dynamin-related) [General function prediction only]
Dynamin central region; pfam01031
Dynamin GTPase effector domain; pfam02212
tyrosyl-tRNA synthetase; Validated
catalytic core domain of tyrosinyl-tRNA synthetase; cd00805
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
C2A domain first repeat present in Synaptotagmins 1, 5, 6, 9, and 10; cd08385
C2 domain second repeat present in Synaptotagmins 3, 5, 6, 9, and 10; cd08403
DIE2/ALG10 family; pfam04922
DIE2/ALG10 family; pfam04922
C2 domain first repeat in Copine; cd04048
C2 domain second repeat in Copine; cd04047
VWA Copine: Copines are phospholipid-binding proteins originally identified in paramecium. They are found in human and orthologues have been found in C. elegans and Arabidopsis Thaliana. None have been found in D. Melanogaster or S. Cereviciae; cd01459
Kinesin motor domain, KIF4-like subfamily. Members of this group seem to perform a variety of functions, and have been implicated in neuronal organelle transport and chromosome segregation during mitosis. This catalytic (head) domain has ATPase activity...; cd01372
Kinesin motor, catalytic domain. ATPase; smart00129
Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta subunits, the two subunits...; cd00890
Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; COG2882
ATP synthase B/B' CF(0); cl07975
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
Kinesin motor domain, KIF4-like subfamily. Members of this group seem to perform a variety of functions, and have been implicated in neuronal organelle transport and chromosome segregation during mitosis. This catalytic (head) domain has ATPase activity...; cd01372
Kinesin motor, catalytic domain. ATPase; smart00129
Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta subunits, the two subunits...; cd00890
Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; COG2882
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; cl12013
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
Kinesin motor domain, KIF4-like subfamily. Members of this group seem to perform a variety of functions, and have been implicated in neuronal organelle transport and chromosome segregation during mitosis. This catalytic (head) domain has ATPase activity...; cd01372
Kinesin motor, catalytic domain. ATPase; smart00129
Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta subunits, the two subunits...; cd00890
Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; COG2882
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; cl12013
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
Kinesin motor domain, KIF4-like subfamily. Members of this group seem to perform a variety of functions, and have been implicated in neuronal organelle transport and chromosome segregation during mitosis. This catalytic (head) domain has ATPase activity...; cd01372
Kinesin motor, catalytic domain. ATPase; smart00129
Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta subunits, the two subunits...; cd00890
Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; COG2882
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protei; TIGR00954
ABC transporter transmembrane region 2; pfam06472
Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome.  The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed...; cd03223
Sugar (and other) transporter; pfam00083
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Ankyrin repeats (3 copies); pfam12796
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
GTPase SAR1 and related small G proteins [General function prediction only]
Ras of complex proteins (Roc) C-terminal of Roc (COR) domain family; cd09914
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
First Ig domain of contactin-1; cd05849
Immunoglobulin I-set domain; pfam07679
Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins; cd05727
Immunoglobulin I-set domain; pfam07679
Third Ig domain of contactin-1; cd05851
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Fifth Ig domain of contactin-1; cd05852
Immunoglobulin I-set domain; pfam07679
Sixth Ig domain of contactin; cd04970
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
First Ig domain of contactin-1; cd05849
Immunoglobulin I-set domain; pfam07679
Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins; cd05727
Immunoglobulin I-set domain; pfam07679
Third Ig domain of contactin-1; cd05851
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Fifth Ig domain of contactin-1; cd05852
Immunoglobulin I-set domain; pfam07679
Sixth Ig domain of contactin; cd04970
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
First Ig domain of contactin-1; cd05849
Immunoglobulin I-set domain; pfam07679
Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins; cd05727
Immunoglobulin I-set domain; pfam07679
Third Ig domain of contactin-1; cd05851
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Fifth Ig domain of contactin-1; cd05852
Immunoglobulin I-set domain; pfam07679
Sixth Ig domain of contactin; cd04970
First Ig domain of contactin-1; cd05849
Immunoglobulin I-set domain; pfam07679
Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins; cd05727
Immunoglobulin I-set domain; pfam07679
Third Ig domain of contactin-1; cd05851
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Fifth Ig domain of contactin-1; cd05852
Immunoglobulin I-set domain; pfam07679
Sixth Ig domain of contactin; cd04970
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Domain present in PSD-95, Dlg, and ZO-1/2; smart00228
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
GT8_like_2 represents a subfamily of GT8 with unknown function; cd06430
GT8_like_2 represents a subfamily of GT8 with unknown function; cd06430
Zinc finger domain; smart00547
Zinc finger domain; smart00547
Zinc finger domain; smart00547
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Transcriptional regulatory protein LGE1; pfam11488
Transcriptional regulatory protein LGE1; pfam11488
Transcriptional regulatory protein LGE1; pfam11488
Transcriptional regulatory protein LGE1; pfam11488
Transcriptional regulatory protein LGE1; pfam11488
Transcriptional regulatory protein LGE1; pfam11488
Transcriptional regulatory protein LGE1; pfam11488
The PET domain of Prickle; cd09827
The first LIM domain of Prickle; cd09415
The second LIM domain of Prickle; cd09418
The third LIM domain of Prickle; cd09420
The PET domain of Prickle; cd09827
The first LIM domain of Prickle; cd09415
The second LIM domain of Prickle; cd09418
The third LIM domain of Prickle; cd09420
The PET domain of Prickle; cd09827
The first LIM domain of Prickle; cd09415
The second LIM domain of Prickle; cd09418
The third LIM domain of Prickle; cd09420
The PET domain of Prickle; cd09827
The first LIM domain of Prickle; cd09415
The second LIM domain of Prickle; cd09418
The third LIM domain of Prickle; cd09420
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that...; cd04273
Thrombospondin type 1 repeats; smart00209
ADAM-TS Spacer 1; pfam05986
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 domain; cl15278
Thrombospondin type 1 domain; cl15278
GON domain; pfam08685
Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); cl00130
Pseudouridine synthase, TruD family; cd02576
Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); cl00130
Pseudouridine synthase, TruD family; cd02576
Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); cl00130
Pseudouridine synthase, TruD family; cd02576
Death domain of Interleukin-1 Receptor-Associated Kinase 4; cd08793
Protein tyrosine kinase; pfam07714
Catalytic domain of Protein Kinases; cd00180
Death domain of Interleukin-1 Receptor-Associated Kinase 4; cd08793
Protein tyrosine kinase; pfam07714
Catalytic domain of Protein Kinases; cd00180
Protein tyrosine kinase; pfam07714
Catalytic domain of Protein Kinases; cd00180
Protein tyrosine kinase; pfam07714
Catalytic domain of Protein Kinases; cd00180
Protein tyrosine kinase; pfam07714
Catalytic domain of Protein Kinases; cd00180
N-terminal ADF domain of twinfilin and related proteins; cd11285
C-terminal ADF domain of twinfilin and related proteins; cd11284
N-terminal ADF domain of twinfilin and related proteins; cd11285
C-terminal ADF domain of twinfilin and related proteins; cd11284
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
von Willebrand factor type C domain; cl02515
Calcium-binding EGF domain; pfam07645
EGF domain; pfam12947
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF domain; pfam07645
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
von Willebrand factor type C domain; cl02515
Calcium-binding EGF domain; pfam07645
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF domain; pfam07645
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
von Willebrand factor type C domain; cl02515
Calcium-binding EGF domain; pfam07645
EGF domain; pfam12947
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF domain; pfam07645
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
von Willebrand factor type C domain; cl02515
Calcium-binding EGF domain; pfam07645
EGF domain; pfam12947
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF domain; pfam07645
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
von Willebrand factor type C domain; cl02515
Calcium-binding EGF domain; pfam07645
EGF domain; pfam12947
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF domain; pfam07645
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Calcium-activated chloride channel; pfam04547
Calcium-activated chloride channel; pfam04547
Calcium-activated chloride channel; pfam04547
Calcium-activated chloride channel; pfam04547
ARID/BRIGHT DNA binding domain; smart01014
RFX DNA-binding domain; pfam02257
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Amino acid permeases [Amino acid transport and metabolism]; COG0814
Transmembrane amino acid transporter protein; cl15776
Amino acid permeases [Amino acid transport and metabolism]; COG0814
Transmembrane amino acid transporter protein; cl15776
Transmembrane amino acid transporter protein; cl15776
Transmembrane amino acid transporter protein; cl15776
Transmembrane amino acid transporter protein; cl15776
Transmembrane amino acid transporter protein; cl15776
Transmembrane amino acid transporter protein; cl15776
Transmembrane amino acid transporter protein; cl15776
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; cl01053
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13432
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Potential Monad-binding region of RPAP3; pfam13877
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13432
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Endomucin; pfam07010
Potential Monad-binding region of RPAP3; pfam13877
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13432
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Endomucin; pfam07010
Potential Monad-binding region of RPAP3; pfam13877
Somatomedin B -like domains; smart00201
Endoribonuclease XendoU; pfam09412
Somatomedin B -like domains; smart00201
Endoribonuclease XendoU; pfam09412
Somatomedin B domain; pfam01033
Somatomedin B -like domains; smart00201
Endoribonuclease XendoU; pfam09412
DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in Epac-like proteins. Epac (exchange proteins directly activated by cAMP) proteins are GEFs (guanine-nucleotide-exchange factors) for the small GTPases, Rap1 and Rap2. They are directly regulated by...; cd04437
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in Epac-like proteins. Epac (exchange proteins directly activated by cAMP) proteins are GEFs (guanine-nucleotide-exchange factors) for the small GTPases, Rap1 and Rap2. They are directly regulated by...; cd04437
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in Epac-like proteins. Epac (exchange proteins directly activated by cAMP) proteins are GEFs (guanine-nucleotide-exchange factors) for the small GTPases, Rap1 and Rap2. They are directly regulated by...; cd04437
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
Histone deacetylase 7; cd10008
Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; COG0123
Histone deacetylase 7; cd10008
Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; COG0123
DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers; cd06955
The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators; cl11397
The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily; cd06933
DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers; cd06955
The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators; cl11397
The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily; cd06933
DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers; cd06955
The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators; cl11397
The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily; cd06933
Protein of unknown function (DUF1356); pfam07092
Protein of unknown function (DUF1356); pfam07092
Protein of unknown function (DUF1356); pfam07092
Protein of unknown function (DUF1356); pfam07092
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Fibrillar collagens C-terminal domain; smart00038
von Willebrand factor type C domain; pfam00093
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Fibrillar collagens C-terminal domain; smart00038
Ulp1 protease family, C-terminal catalytic domain; pfam02902
Ulp1 protease family, C-terminal catalytic domain; pfam02902
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent...; cd00764
6-phosphofructokinase, eukaryotic type; TIGR02478
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent...; cd00764
6-phosphofructokinase, eukaryotic type; TIGR02478
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent...; cd00764
6-phosphofructokinase, eukaryotic type; TIGR02478
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent...; cd00764
6-phosphofructokinase, eukaryotic type; TIGR02478
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13857
SOCS (suppressors of cytokine signaling) box of ASB8-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. Human ASB8 is highly transcribed in skeletal muscle and in lung carcinoma cell lines. The...; cd03727
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Antagonist of mitotic exit network protein 1; cl15308
Leucine Rich repeats (2 copies); pfam12799
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have...; cd00119
Potential DNA-binding domain; pfam13891
Potential DNA-binding domain; pfam13891
Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, cyclin H subunit [Cell division and chromosome partitioning / Transcription / DNA replication, recombination, and repair]; COG5333
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Adenylyl- / guanylyl cyclase, catalytic domain; smart00044
cyclase homology domain; cd07302
Domain of Unknown Function (DUF1053); pfam06327
Adenylyl- / guanylyl cyclase, catalytic domain; smart00044
cyclase homology domain; cd07302
Adenylyl- / guanylyl cyclase, catalytic domain; smart00044
cyclase homology domain; cd07302
Domain of Unknown Function (DUF1053); pfam06327
Adenylyl- / guanylyl cyclase, catalytic domain; smart00044
cyclase homology domain; cd07302
Voltage gated calcium channel subunit beta domain 4Aa N terminal; pfam12052
Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3; cd12042
Guanylate kinase; pfam00625
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Voltage gated calcium channel subunit beta domain 4Aa N terminal; pfam12052
Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3; cd12042
Guanylate kinase; pfam00625
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Voltage gated calcium channel subunit beta domain 4Aa N terminal; pfam12052
Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta3; cd12042
Guanylate kinase; pfam00625
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta; cd11863
Guanylate kinase; pfam00625
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
DEAD-like helicases superfamily; smart00487
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Rnd1/Rho6 GTPases; cd04174
GTPase SAR1 and related small G proteins [General function prediction only]
FKBP-type peptidyl-prolyl cis-trans isomerase; pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase; pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase; pfam00254
GTPase SAR1 and related small G proteins [General function prediction only]
ADP-ribosylation factor-1 (Arf1) and ADP-ribosylation factor-5 (Arf5); cd04150
wnt family; pfam00110
found in Wnt-1; smart00097
found in Wnt-1; smart00097
wnt family; pfam00110
The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; cd04618
FOG: CBS domain [General function prediction only]
The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; cd04641
FOG: CBS domain [General function prediction only]
The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; cd04618
FOG: CBS domain [General function prediction only]
The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; cd04641
FOG: CBS domain [General function prediction only]
The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; cd04618
FOG: CBS domain [General function prediction only]
The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; cd04641
FOG: CBS domain [General function prediction only]
PHD-like zinc-binding domain; pfam13771
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
PHD-finger; pfam00628
PHD-finger; pfam00628
PHD-finger; pfam00628
PHD zinc finger; smart00249
High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I...; cd00084
PHD-like zinc-binding domain; pfam13771
PHD zinc finger; smart00249
F/Y-rich N-terminus; pfam05964
FY-rich domain, C-terminal region; smart00542
Proteins containing SET domain [General function prediction only]
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Ras Homolog Enriched in Brain (RheB) is a small GTPase; cd04137
GTPase SAR1 and related small G proteins [General function prediction only]
Hedgehog amino-terminal signalling domain; pfam01085
Hint module; pfam01079
Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; cd00081
LMBR1-like membrane protein; pfam04791
tubulin alpha chain; Provisional
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02186
tubulin alpha chain; Provisional
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02186
tubulin alpha chain; Provisional
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02186
tubulin alpha chain; Provisional
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02186
tubulin alpha chain; Provisional
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02186
Intermediate filament head (DNA binding) region; pfam04732
Intermediate filament protein; pfam00038
large tegument protein UL36; Provisional
C1q domain; pfam00386
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
Protein of unknown function (DUF1387); pfam07139
PAS domain; pfam13426
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
Ion transport protein; pfam00520
Ion channel; pfam07885
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
N-terminal region of micro-spherule protein; pfam13325
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
N-terminal region of micro-spherule protein; pfam13325
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
FF domain; pfam01846
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
FF domain; pfam01846
Contains two conserved F residues; smart00441
Diaphanous GTPase-binding Domain; pfam06371
Diaphanous FH3 Domain; pfam06367
Formin Homology 2 Domain; pfam02181
Formin Homology 2 Domain; smart00498
Diaphanous GTPase-binding Domain; pfam06371
Diaphanous FH3 Domain; pfam06367
Formin Homology 2 Domain; pfam02181
Formin Homology 2 Domain; smart00498
BAX inhibitor (BI)-1; cd10430
BAX inhibitor (BI)-1; cd10430
Bicoid-interacting protein 3 (Bin3); pfam06859
Proteins similar to and including lifeguard (LFG), a putative regulator of apoptosis; cd10428
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; cd00333
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
RhoGAP_MgcRacGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin...; cd04382
GTPase-activator protein for Rho-like GTPases; smart00324
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
RhoGAP_MgcRacGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin...; cd04382
GTPase-activator protein for Rho-like GTPases; smart00324
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
RhoGAP_MgcRacGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in MgcRacGAP proteins. MgcRacGAP plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin...; cd04382
GTPase-activator protein for Rho-like GTPases; smart00324
sodium channel transporter; TIGR00859
sodium channel transporter; TIGR00859
Amiloride-sensitive sodium channel; cl02990
sodium channel transporter; TIGR00859
Bindin; pfam02084
SWIB-domain-containing proteins implicated in chromatin remodeling [Chromatin structure and dynamics]
SWI complex, BAF60b domains; smart00151
Bindin; pfam02084
SWIB-domain-containing proteins implicated in chromatin remodeling [Chromatin structure and dynamics]
SWI complex, BAF60b domains; smart00151
glycerol-3-phosphate dehydrogenase (NAD(+)); TIGR03376
NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; pfam01210
NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; pfam07479
glycerol-3-phosphate dehydrogenase (NAD(+)); TIGR03376
NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; pfam01210
NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; pfam07479
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
TRAM, LAG1 and CLN8 homology domains; smart00724
The Lim domain of Epithelial Protein Lost in Neoplasm (Eplin); cd09485
The Lim domain of Epithelial Protein Lost in Neoplasm (Eplin); cd09485
The Lim domain of Epithelial Protein Lost in Neoplasm (Eplin); cd09485
The Lim domain of Epithelial Protein Lost in Neoplasm (Eplin); cd09485
High molecular weight glutenin subunit; pfam03157
La RNA-binding domain of La-related protein 4; cd08035
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
La RNA-binding domain of La-related protein 4; cd08035
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
La RNA-binding domain of La-related protein 4; cd08035
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
La RNA-binding domain of La-related protein 4; cd08035
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
La RNA-binding domain of La-related protein 4; cd08035
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
La RNA-binding domain of La-related protein 4; cd08035
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
DMAP1-binding Domain; pfam06464
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; COG0318
AMP-binding enzyme; pfam00501
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; COG0318
AMP-binding enzyme; pfam00501
pKID domain; pfam02173
bZIP transcription factor; pfam00170
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Methyltransferase domain; pfam13847
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Hypoxia induced protein conserved region; pfam04588
NRAMP (natural resistance-associated macrophage protein) metal ion transporters; TIGR01197
Natural resistance-associated macrophage protein; pfam01566
NRAMP (natural resistance-associated macrophage protein) metal ion transporters; TIGR01197
Natural resistance-associated macrophage protein; pfam01566
NRAMP (natural resistance-associated macrophage protein) metal ion transporters; TIGR01197
Natural resistance-associated macrophage protein; pfam01566
NRAMP (natural resistance-associated macrophage protein) metal ion transporters; TIGR01197
Natural resistance-associated macrophage protein; pfam01566
NRAMP (natural resistance-associated macrophage protein) metal ion transporters; TIGR01197
Natural resistance-associated macrophage protein; pfam01566
NRAMP (natural resistance-associated macrophage protein) metal ion transporters; TIGR01197
Natural resistance-associated macrophage protein; pfam01566
NRAMP (natural resistance-associated macrophage protein) metal ion transporters; TIGR01197
Natural resistance-associated macrophage protein; pfam01566
LETM1-like protein; pfam07766
LETM1-like protein; pfam07766
CP2 transcription factor; pfam04516
SAM domain of TFCP2 transcription factors; cd09589
CP2 transcription factor; pfam04516
SAM domain of TFCP2 transcription factors; cd09589
CP2 transcription factor; pfam04516
SAM domain of TFCP2 transcription factors; cd09589
Pou domain - N-terminal to homeobox domain; cl02582
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
DAZ associated protein 2 (DAZAP2); pfam11029
DAZ associated protein 2 (DAZAP2); pfam11029
DAZ associated protein 2 (DAZAP2); pfam11029
DAZ associated protein 2 (DAZAP2); pfam11029
DAZ associated protein 2 (DAZAP2); pfam11029
DAZ associated protein 2 (DAZAP2); pfam11029
BAR domain; smart00721
The Bin/Amphiphysin/Rvs (BAR) domain of Bridging integrator 2; cd07612
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
pp-GalNAc-T initiates the formation of mucin-type O-linked glycans; cd02510
Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; COG0463
Ricin-type beta-trefoil lectin domain; pfam00652
Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; cd00161
anion exchange protein; TIGR00834
HCO3- transporter family; pfam00955
Band 3 cytoplasmic domain; pfam07565
HCO3- transporter family; pfam00955
anion exchange protein; TIGR00834
HCO3- transporter family; pfam00955
Band 3 cytoplasmic domain; pfam07565
HCO3- transporter family; pfam00955
Putative binding domain; pfam13900
Band 3 cytoplasmic domain; pfam07565
HCO3- transporter family; pfam00955
Ion transport protein; pfam00520
Domain of unknown function (DUF3451); pfam11933
Ion transport protein; pfam00520
Sodium ion transport-associated; pfam06512
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Domain of unknown function (DUF3451); pfam11933
Ion transport protein; pfam00520
Sodium ion transport-associated; pfam06512
Ion transport protein; pfam00520
Ion transport protein; pfam00520
ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; COG0464
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Activin types I and II receptor domain; pfam01064
Transforming growth factor beta type I GS-motif; pfam08515
Protein kinase domain; pfam00069
Catalytic domain of Protein Kinases; cd00180
Protein Kinases, catalytic domain; cl09925
Activin types I and II receptor domain; pfam01064
Transforming growth factor beta type I GS-motif; pfam08515
Protein kinase domain; pfam00069
Catalytic domain of Protein Kinases; cd00180
Protein Kinases, catalytic domain; cl09925
Activin types I and II receptor domain; pfam01064
Transforming growth factor beta type I GS-motif; pfam08515
Protein kinase domain; pfam00069
Catalytic domain of Protein Kinases; cd00180
Protein Kinases, catalytic domain; cl09925
Activin types I and II receptor domain; pfam01064
Transforming growth factor beta type I GS-motif; pfam08515
Protein kinase domain; pfam00069
Catalytic domain of Protein Kinases; cd00180
Protein Kinases, catalytic domain; cl09925
Activin types I and II receptor domain; pfam01064
Transforming growth factor beta type I GS-motif; pfam08515
Protein kinase domain; pfam00069
Catalytic domain of Protein Kinases; cd00180
Protein Kinases, catalytic domain; cl09925
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
DNA-binding domain of the orphan nuclear receptor, nerve growth factor-induced-B; cd06969
The ligand binding domain of  Nurr1, a member of conserved family of nuclear receptors; cd07348
DNA-binding domain of the orphan nuclear receptor, nerve growth factor-induced-B; cd06969
The ligand binding domain of  Nurr1, a member of conserved family of nuclear receptors; cd07348
DNA-binding domain of the orphan nuclear receptor, nerve growth factor-induced-B; cd06969
The ligand binding domain of  Nurr1, a member of conserved family of nuclear receptors; cd07348
Protein of unknown function (DUF1649); pfam07855
Protein of unknown function (DUF1649); pfam07855
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Bacterial protein of unknown function (DUF883); cl01888
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein tyrosine phosphatase, catalytic domain motif; smart00404
C2 domain of PTEN tumour-suppressor protein; pfam10409
Src homology 2 domain found in Tensin-like proteins; cd09927
Pleckstrin homology-like domain; cl00273
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein tyrosine phosphatase, catalytic domain motif; smart00404
C2 domain of PTEN tumour-suppressor protein; pfam10409
Src homology 2 domain found in Tensin-like proteins; cd09927
Pleckstrin homology-like domain; cl00273
Protein tyrosine phosphatase, catalytic domain motif; smart00404
C2 domain of PTEN tumour-suppressor protein; pfam10409
Src homology 2 domain found in Tensin-like proteins; cd09927
Pleckstrin homology-like domain; cl00273
SPRY domain; pfam00622
SPRY domain; pfam00622
Insulin growth factor-binding protein homologues; smart00121
Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases; cd00191
MBOAT, membrane-bound O-acyltransferase family; pfam03062
Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]; COG0076
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; cd06450
Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]; COG0076
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; cd06450
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; cl00321
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Integrin beta subunits (N-terminal portion of extracellular region); smart00187
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Integrin beta tail domain; pfam07965
Integrin beta cytoplasmic domain; pfam08725
DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers; cd06964
The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily; cd06937
DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers; cl02596
The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily; cd06937
DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers; cd06964
The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily; cd06937
DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers; cd06964
The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily; cd06937
DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers; cl02596
The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily; cd06937
Major Facilitator Superfamily; pfam07690
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cl11420
Major Facilitator Superfamily; pfam07690
Peptidase family C50; pfam03568
Predicted prefoldin, molecular chaperone implicated in de novo protein folding [Posttranslational modification, protein turnover, chaperones]; COG1730
Prefoldin alpha subunit; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta...; cd00584
Prefoldin alpha subunit; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta...; cd00584
Uncharacterized protein family (UPF0160); pfam03690
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Activin types I and II receptor domain; pfam01064
Protein kinase domain; pfam00069
Catalytic domain of Protein Kinases; cd00180
Catalytic domain of Protein Kinases; cd00180
Activin types I and II receptor domain; pfam01064
Catalytic domain of Protein Kinases; cd00180
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
Transcription elongation factor [Transcription]; COG0195
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
Transcription elongation factor [Transcription]; COG0195
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
Transcription elongation factor [Transcription]; COG0195
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
Transcription elongation factor [Transcription]; COG0195
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
Transcription elongation factor [Transcription]; COG0195
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
Transcription elongation factor [Transcription]; COG0195
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
Transcription elongation factor [Transcription]; COG0195
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105