Myb/SANT-like DNA-binding domain; pfam13873
Nanos RNA binding domain; pfam05741
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; cd06583
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Hypoxia-inducible factor-1; pfam11413
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Hypoxia-inducible factor-1; pfam11413
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Hypoxia-inducible factor-1; pfam11413
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Putative binding domain; pfam13900
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
PP5, C-terminal metallophosphatase domain; cd07417
Protein phosphatase 2A homologues, catalytic domain; smart00156
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
PPP5 TPR repeat region; pfam08321
PP5, C-terminal metallophosphatase domain; cd07417
Protein phosphatase 2A homologues, catalytic domain; smart00156
transcription termination factor Rho; Provisional
PPP5 TPR repeat region; pfam08321
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; cl10458
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors; cd00068
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Pleckstrin homology-like domain; cl00273
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Pleckstrin homology-like domain; cl00273
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Pleckstrin homology-like domain; cl00273
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Pleckstrin homology-like domain; cl00273
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Striatin family; pfam08232
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
Striatin family; pfam08232
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
LicD family; pfam04991
LicD family; pfam04991
Sodium:dicarboxylate symporter family; pfam00375
Na+/H+-dicarboxylate symporters [Energy production and conversion]; COG1301
Na+/H+-dicarboxylate symporters [Energy production and conversion]; COG1301
Sodium:dicarboxylate symporter family; pfam00375
Na+/H+-dicarboxylate symporters [Energy production and conversion]; COG1301
Sodium:dicarboxylate symporter family; pfam00375
Clathrin adaptor complex small chain; cl02092
Clathrin adaptor complex small chain; pfam01217
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Contains two conserved F residues; smart00441
Contains two conserved F residues; smart00441
Contains two conserved F residues; smart00441
RhoGAP_p190: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of p190-like proteins. p190, also named RhoGAP5, plays a role in neuritogenesis and axon branch stability. p190 shows a preference for Rho, over Rac and Cdc42, and...; cd04373
GTPase-activator protein for Rho-like GTPases; smart00324
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
zinc finger; smart00356
zinc finger; smart00356
Ubiquitin activating enzyme (E1) subunit Aos1. Aos1 is part of the heterodimeric activating enzyme (E1), specific for the SUMO family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to...; cd01492
Ubiquitin activating enzyme (E1) subunit Aos1. Aos1 is part of the heterodimeric activating enzyme (E1), specific for the SUMO family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to...; cd01492
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Ubiquitin activating enzyme (E1) subunit Aos1. Aos1 is part of the heterodimeric activating enzyme (E1), specific for the SUMO family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to...; cd01492
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
HrpA-like helicases [DNA replication, recombination, and repair]; COG1643
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Helicase associated domain (HA2); pfam04408
Oligonucleotide/oligosaccharide-binding (OB)-fold; pfam07717
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
sodium/calcium exchanger 1; TIGR00845
Sodium/calcium exchanger protein; pfam01699
Calx-beta domain; pfam03160
Domains in Na-Ca exchangers and integrin-beta4; smart00237
Sodium/calcium exchanger protein; pfam01699
Family description; pfam13517
Zinc finger, C2H2 type; cl15478
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
ELM2 domain; pfam01448
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cl15779
Eps15 homology domain (EHD), C-terminal domain; cd09913
Dynamin family; pfam00350
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Nop53 (60S ribosomal biogenesis); pfam07767
selT/selW/selH selenoprotein domain; TIGR02174
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cl00084
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Sulfotransferase family; cl14559
Sulfotransferase domain; pfam00685
Fibronectin type II domain; pfam00040
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and...; cd00062
Fibronectin type II domain; pfam00040
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and...; cd00062
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and...; cd00062
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and...; cd00062
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Group IVC cytoplasmic phospholipase A2; catalytic domain; Ca-independent; cd07202
Patatins and Phospholipases; cl11396
Group IVC cytoplasmic phospholipase A2; catalytic domain; Ca-independent; cd07202
Patatins and Phospholipases; cl11396
Group IVC cytoplasmic phospholipase A2; catalytic domain; Ca-independent; cd07202
Patatins and Phospholipases; cl11396
DNA ligase I, ATP-dependent (dnl1); TIGR00574
Adenylation domain of eukaryotic DNA Ligase I; cd07900
The Oligonucleotide/oligosaccharide binding (OB)-fold domain of ATP-dependent DNA ligase I is a DNA-binding module that is part of the catalytic core unit; cd07969
Function to find; pfam13553
Caspase activation and recruitment domain: a protein-protein interaction domain; cd01671
Function to find; pfam13553
Caspase activation and recruitment domain: a protein-protein interaction domain; cd01671
Function to find; pfam13553
Caspase activation and recruitment domain: a protein-protein interaction domain; cd01671
Function to find; pfam13553
Function to find; pfam13553
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
chromosome segregation protein SMC, common bacterial type; TIGR02168
phosphodiesterase; Provisional
PMP-22/EMP/MP20/Claudin family; pfam00822
Membrane-associating domain; pfam01284
ER lumen protein retaining receptor; pfam00810
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family; cd06378
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Ligand-gated ion channel; pfam00060
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Histone-binding protein RBBP4 or subunit C of CAF1 complex; pfam12265
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Inward rectifier potassium channel; pfam01007
Inward rectifier potassium channel; pfam01007
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor...; cd00171
Cytohesin Pleckstrin homology (PH) domain; cd01252
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor...; cd00171
Cytohesin Pleckstrin homology (PH) domain; cd01252
Protein tyrosine kinase; pfam07714
Protein Kinases, catalytic domain; cl09925
Sulfotransferase family; cl14559
Sulfotransferase domain; pfam00685
Sulfotransferase family; cl14559
Sulfotransferase domain; pfam00685
Protein of unknown function (DUF1669); pfam07894
Catalytic domain of phospholipase D superfamily proteins; cl15239
Ribosomal protein L18e/L15; cl12022
Ribosomal protein L18e/L15; cl12022
Diacylglycerol kinase catalytic domain; pfam00781
Diacylglycerol kinase catalytic domain; pfam00781
Diacylglycerol kinase catalytic domain; pfam00781
Diacylglycerol kinase catalytic domain; pfam00781
Diacylglycerol kinase catalytic domain; pfam00781
Basic region leucine zipper; pfam07716
Carbonic anhydrase alpha related protein: groups X, XI and related proteins. This subgroup contains carbonic anhydrase related proteins (CARPs) X and XI, which have been implicated in various biological processes of the central nervous system. CARPs are...; cd03121
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
NTR domain, Netrin-1-like subfamily; The C-terminal NTR domain of netrins is also called domain C in the context of C. elegans netrin UNC-6. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration...; cd03579
Glycosyl transferase family 11; pfam01531
Alpha-1,2-fucosyltransferase; cd11301
Glycosyl transferase family 11; pfam01531
Alpha-1,2-fucosyltransferase; cd11301
SAP domain; pfam02037
SAP domain; pfam02037
Ras association (RalGDS/AF-6) domain; pfam00788
DIL domain; pfam01843
Glycosyl transferase family 11; pfam01531
Alpha-1,2-fucosyltransferase; cd11301
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; cd01557
branched-chain amino acid aminotransferase; Provisional
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; cd01557
retinal dehydrogenase-like, classical (c) SDR; cd08933
3-ketoacyl-(acyl-carrier-protein) reductase; Validated; PRK05653
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
Phosphatase-1 catalytic subunit binding region; pfam10488
Tub family; pfam01167
Predicted dehydrogenases and related proteins [General function prediction only]; COG0673
Oxidoreductase family, NAD-binding Rossmann fold; pfam01408
Oxidoreductase family, C-terminal alpha/beta domain; cl11611
apoptosis regulator; TIGR00865
Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane...; cd06845
apoptosis regulator; TIGR00865
Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane...; cd06845
apoptosis regulator; TIGR00865
Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane...; cd06845
apoptosis regulator; TIGR00865
Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane...; cd06845
Ferritin iron storage proteins; cd00904
Ferritin-like domain; pfam00210
Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; cl10013
Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; cl10013
Glycogen synthase, which is most closely related to the GT1 family of glycosyltransferases, catalyzes the transfer of a glucose molecule from UDP-glucose to a terminal branch of a glycogen molecule, a rate-limit step of glycogen biosynthesis. GSY2, the...; cd03793
Glycogen synthase; pfam05693
TIP49 C-terminus; pfam06068
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Glycoprotein hormone beta chain homologues; cd00069
Glycoprotein hormone beta chain homologues; cd00069
Glycoprotein hormone beta chain homologues; cd00069
Glycoprotein hormone beta chain homologues; cd00069
Glycoprotein hormone beta chain homologues; cd00069
Glycoprotein hormone beta chain homologues; cd00069
Glycoprotein hormone beta chain homologues; cd00069
Nerve growth factor family; pfam00243
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
U1 small nuclear ribonucleoprotein of 70kDa MW N terminal; pfam12220
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
L27 domain; pfam02828
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
SAM domain of liprin-alpha1,2,3,4 proteins repeat 1; cd09562
Sterile alpha motif; smart00454
SAM domain of liprin-alpha1,2,3,4 proteins repeat 2; cd09565
Sterile alpha motif; smart00454
SAM domain of liprin-alpha1,2,3,4 proteins repeat 3; cd09568
Sterile alpha motif; smart00454
Ion transport protein; pfam00520
acetyl-CoA carboxylase beta subunit; Reviewed; CHL00174
Neurotransmitter transporter 5; solute-binding domain; cd11502
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment...; cd03160
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment...; cd03160
TEA/ATTS domain family; pfam01285
TEA/ATTS domain family; pfam01285
TEA/ATTS domain family; pfam01285
TEA/ATTS domain family; pfam01285
TEA/ATTS domain family; pfam01285
TEA/ATTS domain family; cl02603
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
Na(+)-dependent inorganic phosphate cotransporter; TIGR00894
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
pre-RNA processing PIH1/Nop17; pfam08190
NAD(P)+-dependent aldehyde dehydrogenase superfamily; cl11961
Aldehyde dehydrogenase family; pfam00171
NAD(P)+-dependent aldehyde dehydrogenase superfamily; cl11961
NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; COG1012
NAD(P)+-dependent aldehyde dehydrogenase superfamily; cl11961
NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; COG1012
NAD(P)+-dependent aldehyde dehydrogenase superfamily; cl11961
NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; COG1012
flt3 ligand; pfam02947
flt3 ligand; pfam02947
flt3 ligand; pfam02947
60S ribosomal protein L13a; Provisional
Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; cd00392
Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; cl00333
40S ribosomal protein S11; Provisional
Class I Histocompatibility antigen, domains alpha 1 and 2; pfam00129
Immunoglobulin domain; cl11960
Class I Histocompatibility antigen, domains alpha 1 and 2; pfam00129
Immunoglobulin domain; cl11960
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cl08302
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cl15348
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cl15348
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cl15348
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cl15348
Domain containing Gla (gamma-carboxyglutamate) residues; smart00069
Domain of unknown function (DUF4211); pfam13926
R-Ras2/TC21, M-Ras/R-Ras3; cd04145
Interferon Regulatory Factor (IRF); also known as tryptophan pentad repeat. The family of IRF transcription factors is important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. The...; cd00103
Interferon-regulatory factor 3; pfam10401
Interferon Regulatory Factor (IRF); also known as tryptophan pentad repeat. The family of IRF transcription factors is important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. The...; cd00103
Interferon-regulatory factor 3; pfam10401
Interferon Regulatory Factor (IRF); also known as tryptophan pentad repeat. The family of IRF transcription factors is important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. The...; cd00103
Interferon-regulatory factor 3; pfam10401
Interferon Regulatory Factor (IRF); also known as tryptophan pentad repeat. The family of IRF transcription factors is important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. The...; cl00096
Interferon-regulatory factor 3; pfam10401
Interferon-regulatory factor 3; pfam10401
Interferon-regulatory factor 3; pfam10401
Interferon-regulatory factor 3; pfam10401
Interferon-regulatory factor 3; pfam10401
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Choline/Carnitine o-acyltransferase; pfam00755
Choline/Carnitine o-acyltransferase; pfam00755
Choline/Carnitine o-acyltransferase; pfam00755
Choline/Carnitine o-acyltransferase; pfam00755
Adaptin N terminal region; pfam01602
Adaptin C-terminal domain; smart00809
Alpha adaptin AP2, C-terminal domain; pfam02296
Adaptin N terminal region; pfam01602
Adaptin C-terminal domain; smart00809
Alpha adaptin AP2, C-terminal domain; pfam02296
Mediator complex subunit 25 von Willebrand factor type A; pfam11265
Mediator complex subunit 25 synapsin 1; pfam11235
Mediator complex subunit 25 PTOV activation and synapsin 2; pfam11232
Mediator complex subunit 25 PTOV activation and synapsin 2; pfam11232
Mediator complex subunit 25 PTOV activation and synapsin 2; pfam11232
polynucleotide 5'-kinase 3'-phosphatase; TIGR01663
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
Domain of unknown function (DUF3548); pfam12068
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
Domain of unknown function (DUF3548); pfam12068
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
Flavin containing amine oxidoreductase; pfam01593
NAD(P)-binding Rossmann-like domain; pfam13450
Flavin containing amine oxidoreductase; pfam01593
NAD(P)-binding Rossmann-like domain; pfam13450
Flavin containing amine oxidoreductase; pfam01593
NAD(P)-binding Rossmann-like domain; pfam13450
Flavin containing amine oxidoreductase; pfam01593
NAD(P)-binding Rossmann-like domain; pfam13450
Nsp1-like C-terminal region; pfam05064
Nsp1-like C-terminal region; pfam05064
Nsp1-like C-terminal region; pfam05064
Nsp1-like C-terminal region; pfam05064
Nsp1-like C-terminal region; pfam05064
basic region leucin zipper; smart00338
basic region leucin zipper; smart00338
Immunoglobulin (Ig) domain at the N terminus of Siglec (sialic acid-binding Ig-like lectins); cd05712
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin like; smart00410
Immunoglobulin domain; cd00096
Immunoglobulin (Ig) domain at the N terminus of Siglec (sialic acid-binding Ig-like lectins); cd05712
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin like; smart00410
Immunoglobulin domain; cd00096
zinc-ribbon domain; pfam13248
Double zinc ribbon; pfam12773
putative serine/threonine kinase; Provisional
Protein Kinases, catalytic domain; cl09925
zinc-ribbon domain; pfam13248
Double zinc ribbon; pfam12773
putative serine/threonine kinase; Provisional
Protein Kinases, catalytic domain; cl09925
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Myosin. Large ATPases; smart00242
Myosin motor domain, type II myosins. Myosin II mediates cortical contraction in cell motility, and is the motor in smooth and skeletal muscle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins...; cd01377
Myosin tail; pfam01576
Myosin. Large ATPases; smart00242
Myosin motor domain, type II myosins. Myosin II mediates cortical contraction in cell motility, and is the motor in smooth and skeletal muscle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins...; cd01377
Myosin tail; pfam01576
Myosin. Large ATPases; smart00242
Myosin motor domain, type II myosins. Myosin II mediates cortical contraction in cell motility, and is the motor in smooth and skeletal muscle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins...; cd01377
Myosin tail; pfam01576
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
Cellular and retroviral pepsin-like aspartate proteases; cl11403
Eukaryotic aspartyl protease; pfam00026
DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers; cl02596
The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors; cd06954
The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors; cd06954
DNA polymerase delta catalytic subunit; Provisional
DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase delta, a family-B DNA polymerase; cd05777
DNA polymerase type-B delta subfamily catalytic domain. Three DNA-dependent DNA polymerases type B (alpha, delta, and epsilon) have been identified as essential for nuclear DNA replication in eukaryotes. Presently, no direct data is available regarding...; cd05533
C4-type zinc-finger of DNA polymerase delta; pfam14260
DNA polymerase delta catalytic subunit; Provisional
DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase delta, a family-B DNA polymerase; cd05777
DNA polymerase type-B delta subfamily catalytic domain. Three DNA-dependent DNA polymerases type B (alpha, delta, and epsilon) have been identified as essential for nuclear DNA replication in eukaryotes. Presently, no direct data is available regarding...; cd05533
C4-type zinc-finger of DNA polymerase delta; pfam14260
Ets-domain; pfam00178
Ets-domain; pfam00178
Ets-domain; pfam00178
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C); cd05894
Immunoglobulin I-set domain; pfam07679
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin (Ig)-like domain of titin and similar proteins; cd05748
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Protein of unknown function (DUF3699); pfam12480
Josephin; pfam02099
Josephin; pfam02099
Josephin; pfam02099
Josephin; pfam02099
Josephin; pfam02099
Josephin; pfam02099
Domain of unknown function DUF108; pfam01958
Homoserine dehydrogenase, NAD binding domain; pfam03447
Domain of unknown function DUF108; pfam01958
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
C2A domain first repeat present in Synaptotagmins 1, 5, 6, 9, and 10; cd08385
C2 domain second repeat present in Synaptotagmins 3, 5, 6, 9, and 10; cd08403
C2A domain first repeat present in Synaptotagmins 1, 5, 6, 9, and 10; cd08385
C2 domain second repeat present in Synaptotagmins 3, 5, 6, 9, and 10; cd08403
C2A domain first repeat present in Synaptotagmins 1, 5, 6, 9, and 10; cd08385
C2 domain second repeat present in Synaptotagmins 3, 5, 6, 9, and 10; cd08403
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 1; cd11982
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
SAM domain of Shank1,2,3 family proteins; cd09506
Sterile alpha motif; smart00454
C-type lectin-like domain (CTLD) of the type found in the tetranectin (TN), cartilage derived C-type lectin (CLECSF1), and stem cell growth factor (SCGF); cd03596
7 transmembrane receptor (rhodopsin family); pfam00001
Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; cd07061
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cl00149
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cl00149
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cl00149
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; COG0037
This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; cd01993
TIGR00269 family protein
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig) domain at the N terminus of Siglec (sialic acid-binding Ig-like lectins); cd05712
Immunoglobulin domain; cl11960
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig) domain at the N terminus of Siglec (sialic acid-binding Ig-like lectins); cd05712
Immunoglobulin domain; cl11960
Immunoglobulin like; smart00410
Immunoglobulin (Ig) domain at the N terminus of Siglec (sialic acid-binding Ig-like lectins); cd05712
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin like; smart00410
Immunoglobulin (Ig) domain at the N terminus of Siglec (sialic acid-binding Ig-like lectins); cd05712
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin C-2 Type; smart00408
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin C-2 Type; smart00408
The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; cd01714
Electron transfer flavoprotein domain; pfam01012
The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; cd01714
Electron transfer flavoprotein domain; pfam01012
PMP-22/EMP/MP20/Claudin family; cl15797
PMP-22/EMP/MP20/Claudin family; pfam00822
PMP-22/EMP/MP20/Claudin family; pfam00822
alpha,alpha-trehalose-phosphate synthase [UDP-forming]
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin like; smart00410
Immunoglobulin domain; cl11960
Immunoglobulin C-2 Type; smart00408
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin like; smart00410
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin like; smart00410
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; pfam13927
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; pfam13927
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; pfam13927
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin like; smart00410
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin C-2 Type; smart00408
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; cl11394
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
HEAT repeat; pfam02985
HEAT-like repeat; pfam13513
HEAT repeats; pfam13646
HEAT repeats; pfam13646
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
heptad repeat 1-heptad repeat 2 region (ectodomain) of the transmembrane subunit of the human endogenous retrovirus ENVV1, and related domains; cd09950
heptad repeat 1-heptad repeat 2 region (ectodomain) of the transmembrane subunit of the human endogenous retrovirus ENVV1, and related domains; cd09950
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Vomeronasal organ pheromone receptor family, V1R; cl12106
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
Vomeronasal organ pheromone receptor family, V1R; cl12106
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Zinc finger, C3HC4 type (RING finger); pfam13920
Zinc finger, C3HC4 type (RING finger); pfam13923
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
RasGAP: Ras-GTPase Activating Domain.  RasGAP functions as an enhancer of the hydrolysis of GTP that is bound to Ras-GTPases. Proteins having a RasGAP domain include p120GAP, IQGAP, Rab5-activating protein 6, and Neurofibromin.  Although the Rho (Ras...; cl02569
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Pyrin death domain found in NALP proteins; cd08320
NACHT domain; pfam05729
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Membrane-associating domain; pfam01284
Membrane-associating domain; pfam01284
Membrane-associating domain; pfam01284
Membrane-associating domain; pfam01284
Membrane-associating domain; pfam01284
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
C2 domain in Protein Kinase C (PKC) alpha and gamma; cd04026
Catalytic domain of the Protein Serine/Threonine Kinase, Classical Protein Kinase C; cd05587
Serine/Threonine protein kinases, catalytic domain; smart00220
PMP-22/EMP/MP20/Claudin tight junction; pfam13903
PMP-22/EMP/MP20/Claudin family; cl15797
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Protein implicated in ribosomal biogenesis, Nop56p homolog [Translation, ribosomal structure and biogenesis]; COG1498
NOSIC (NUC001) domain; pfam08060
Putative snoRNA binding domain; pfam01798
Prp31 C terminal domain; pfam09785
Not1 N-terminal domain, CCR4-Not complex component; pfam04065
NOT2 / NOT3 / NOT5 family; pfam04153
TMC domain; pfam07810
TMC domain; pfam07810
MBOAT, membrane-bound O-acyltransferase family; pfam03062
MBOAT, membrane-bound O-acyltransferase family; pfam03062
MBOAT, membrane-bound O-acyltransferase family; pfam03062
MBOAT, membrane-bound O-acyltransferase family; cl00738
tRNA intron endonuclease, catalytic C-terminal domain; pfam01974
tRNA intron endonuclease, catalytic C-terminal domain; pfam01974
Ribosomal protein S4/S9 N-terminal domain; pfam00163
40S ribosomal protein S9; Provisional
S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; cd00165
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
N-terminal domain of the protein encoded by the Drosophila tweety gene and related proteins, a family of chloride ion channels; cd07912
N-terminal domain of the protein encoded by the Drosophila tweety gene and related proteins, a family of chloride ion channels; cl12141
N-terminal domain of the protein encoded by the Drosophila tweety gene and related proteins, a family of chloride ion channels; cl12141
SAC3/GANP/Nin1/mts3/eIF-3 p25 family; pfam03399
zinc finger; smart00356
Protein of unknown function (DUF504); cl00661
AKAP7 2'5' RNA ligase-like domain; pfam10469
P21-Rho-binding domain; pfam00786
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin domain; cl11960
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin domain; cl11960
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin domain; cl11960
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin domain; cl11960
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin domain; cl11960
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin domain; cl11960
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Pyrin death domain found in NALP proteins; cd08320
NACHT domain; pfam05729
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Pyrin death domain found in NALP proteins; cd08320
NACHT domain; pfam05729
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Pyrin death domain found in NALP proteins; cd08320
NACHT domain; pfam05729
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Pyrin death domain found in NALP proteins; cd08320
NACHT domain; pfam05729
ATPases associated with a variety of cellular activities; smart00382
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Pyrin death domain found in NALP proteins; cd08320
NACHT domain; pfam05729
ATPases associated with a variety of cellular activities; smart00382
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Pyrin death domain found in NALP proteins; cd08320
NACHT domain; pfam05729
ATPases associated with a variety of cellular activities; smart00382
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Pyrin death domain found in NALP proteins; cd08320
NACHT domain; pfam05729
ATPases associated with a variety of cellular activities; smart00382
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin domain; cl11960
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin domain; cl11960
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
Immunoglobulin domain; cl11960
short chain dehydrogenase; Provisional
retinol dehydrogenases (retinol-DHs), classical (c) SDRs; cd09807
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Epidermal growth factor receptor kinase substrate (EPS8) Phosphotyrosine-binding (PTB) domain; cd01210
Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins; cd11764
SAM domain of EPS8-like subfamily; cd09540
Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins; cd11764
SAM domain of EPS8-like subfamily; cd09540
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
Troponin; pfam00992
Troponin; pfam00992
Troponin; pfam00992
Troponin; pfam00992
C2A domain first repeat present in Synaptotagmins 1, 5, 6, 9, and 10; cd08385
C2 domain second repeat present in Synaptotagmin 1; cd08402
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
YhhN-like protein; pfam07947
SIT4 phosphatase-associated protein; pfam04499
tegument protein VP11/12; Provisional
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Frag1/DRAM/Sfk1 family; pfam10277
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Cytochrome c oxidase subunit VIb. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; cd00926
Protein of unknown function (DUF3699); pfam12480
Interleukin 11; pfam07400
Interleukin 11; pfam07400
Ribosomal L28e protein family; pfam01778
Ribosomal L28e protein family; pfam01778
Ribosomal L28e protein family; pfam01778
Ribosomal L28e protein family; pfam01778
Ribosomal L28e protein family; pfam01778
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Wnt and FGF inhibitory regulator; pfam13908
Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; cl00220
Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; cl00220
Isochorismatase family; pfam00857
YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; cd01012
Isochorismatase family; pfam00857
YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; cd01012
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
U2 snRNP auxilliary factor, large subunit, splicing factor; TIGR01642
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
U2 snRNP auxilliary factor, large subunit, splicing factor; TIGR01642
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated...; cd03571
ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated...; cd03571
ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated...; cd03571
Pyrin death domain found in NALP proteins; cd08320
NACHT domain; pfam05729
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
RFPL defining motif (RDM); pfam11002
SPRY-associated domain; pfam13765
Domain in SPla and the RYanodine Receptor; smart00449
Pyrin death domain found in NALP proteins; cd08320
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Pyrin death domain found in NALP proteins; cd08320
ATPases associated with a variety of cellular activities; smart00382
NACHT domain; pfam05729
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Pyrin death domain found in NALP proteins; cd08320
NACHT domain; pfam05729
ATPases associated with a variety of cellular activities; smart00382
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Pyrin death domain found in NALP proteins; cd08320
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Pyrin death domain found in NALP proteins; cd08320
NACHT domain; pfam05729
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Galanin; pfam01296
SCAN oligomerization domain; cd07936
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
Zinc finger, C2H2 type; cl15478
SCAN oligomerization domain; cd07936
Zinc finger, C2H2 type; cl15478
SCAN oligomerization domain; cd07936
Zinc finger, C2H2 type; cl15478
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cd02257
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cd02257
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
hypothetical protein
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Vomeronasal organ pheromone receptor family, V1R; cl12106
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
SCAN oligomerization domain; cd07936
SCAN oligomerization domain; cd07936
SCAN oligomerization domain; cd07936
hydroperoxidase II; Provisional; PRK11249
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
SCAN oligomerization domain; cd07936
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
SCAN oligomerization domain; cd07936
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
SCAN oligomerization domain; cd07936
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
SCAN oligomerization domain; cd07936
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Immunoglobulin domain; pfam13895
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13895
First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins; cd05751
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
40S ribosomal protein S5; Provisional
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc finger, C2H2 type; cl15478
long-chain-acyl-CoA synthetase; Validated
AMP-binding enzyme; pfam00501
BTB/POZ domain; pfam00651
C2H2-type zinc finger; pfam13912
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
B-Box-type zinc finger; smart00336
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
PHD-finger; pfam00628
Bromodomain; tif1_like subfamily. Tif1 (transcription intermediary factor 1) is a member of the tripartite motif (TRIM) protein family, which is characterized by a particular domain architecture. It functions by recruiting coactivators and/or...; cd05502
Snf7; pfam03357
Snf7; pfam03357
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
SCAN oligomerization domain; cd07936
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin domain; cl11960
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin domain; cl11960
Immunoglobulin (IG)-like domain of of FcalphaRI; cd05711
Immunoglobulin domain; cl11960
Beta defensin; pfam13841
Beta defensin; pfam13841
Beta defensin; pfam13841
chromosome segregation protein SMC, common bacterial type; TIGR02168
chromosome segregation protein SMC, common bacterial type; TIGR02168
Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; COG5082
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Ubiquitin-like domain of HOIL1; cd01799
Zinc finger domain; smart00547
Ring finger domain; pfam13639
IBR domain; pfam01485
Ubiquitin-like domain of HOIL1; cd01799
Zinc finger domain; smart00547
Ring finger domain; pfam13639
IBR domain; pfam01485
Rab-GTPase-TBC domain; pfam00566
Protein Kinases, catalytic domain; cl09925
Protein kinase domain; pfam00069
Protein Kinases, catalytic domain; cl09925
Protein kinase domain; pfam00069
Protein Kinases, catalytic domain; cl09925
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
ParB-like nuclease domain; cl02129
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Protein of unknown function (DUF1011); pfam06237
Centrosome-associated N terminus; pfam14161
Centrosome-associated C terminus; pfam14160
Centrosome-associated N terminus; pfam14161
Centrosome-associated C terminus; pfam14160
Centrosome-associated N terminus; pfam14161
Centrosome-associated C terminus; pfam14160
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors; cl00066
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors; cl00066
PI31 proteasome regulator N-terminal; pfam11566
PI31 proteasome regulator; pfam08577
PI31 proteasome regulator N-terminal; pfam11566
PI31 proteasome regulator; pfam08577
N terminus of Rad21 / Rec8 like protein; pfam04825
Conserved region of Rad21 / Rec8 like protein; pfam04824
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; cl12013
PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; cd00136
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; cd00136
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; cd00136
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; COG0545
FKBP-type peptidyl-prolyl cis-trans isomerase; pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; COG0545
FKBP-type peptidyl-prolyl cis-trans isomerase; pfam00254
Domain present in Saccharomyces cerevisiae Shp1, Drosophila melanogaster eyes closed gene (eyc), and vertebrate p47; smart00553
p47-like ubiquitin domain; cd01770
Domain present in Saccharomyces cerevisiae Shp1, Drosophila melanogaster eyes closed gene (eyc), and vertebrate p47; smart00553
p47-like ubiquitin domain; cd01770
Domain present in Saccharomyces cerevisiae Shp1, Drosophila melanogaster eyes closed gene (eyc), and vertebrate p47; smart00553
p47-like ubiquitin domain; cd01770
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin variable domain (IgV); cd00099
Immunoglobulin V-set domain; pfam07686
Immunoglobulin variable domain (IgV); cd00099
Signal-regulatory protein (SIRP) immunoglobulin-like domain; cd05772
Immunoglobulin Constant domain; cd00098
Immunoglobulin V-set domain; pfam07686
Immunoglobulin variable domain (IgV); cd00099
Signal-regulatory protein (SIRP) immunoglobulin-like domain; cd05772
Immunoglobulin Constant domain; cd00098
Immunoglobulin V-set domain; pfam07686
Immunoglobulin variable domain (IgV); cd00099
Immunoglobulin V-set domain; pfam07686
Immunoglobulin variable domain (IgV); cd00099
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin variable domain (IgV); cd00099
Immunoglobulin domain; cl11960
Immunoglobulin Constant domain; cd00098
Immunoglobulin V-set domain; pfam07686
Immunoglobulin variable domain (IgV); cd00099
Immunoglobulin domain; cl11960
Immunoglobulin Constant domain; cd00098
Immunoglobulin V-set domain; pfam07686
Immunoglobulin variable domain (IgV); cd00099
Immunoglobulin domain; cl11960
Immunoglobulin Constant domain; cd00098
Immunoglobulin V-set domain; pfam07686
Immunoglobulin variable domain (IgV); cd00099
Immunoglobulin domain; cl11960
Immunoglobulin Constant domain; cd00098
Vertebrate endogenous opioids neuropeptide; pfam01160
Vertebrate endogenous opioids neuropeptide; pfam01160
Vertebrate endogenous opioids neuropeptide; pfam01160
Vertebrate endogenous opioids neuropeptide; pfam01160
Vertebrate endogenous opioids neuropeptide; pfam01160
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Transglutaminase family; pfam00868
Transglutaminase/protease-like homologues; smart00460
Transglutaminase family, C-terminal ig like domain; pfam00927
Transglutaminase family, C-terminal ig like domain; pfam00927
Transglutaminase family; pfam00868
Transglutaminase/protease-like homologues; smart00460
Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]
Transglutaminase family, C-terminal ig like domain; pfam00927
Transglutaminase family, C-terminal ig like domain; pfam00927
Transglutaminase family; pfam00868
Transglutaminase/protease-like homologues; smart00460
Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]
Transglutaminase family, C-terminal ig like domain; pfam00927
Sm protein B; cd01717
Sm protein B; cd01717
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
TMC domain; pfam07810
NOP5NT (NUC127) domain; pfam08156
Protein implicated in ribosomal biogenesis, Nop56p homolog [Translation, ribosomal structure and biogenesis]; COG1498
NOSIC (NUC001) domain; pfam08060
Putative snoRNA binding domain; pfam01798
Isocitrate/isopropylmalate dehydrogenase; cl00445
tartrate dehydrogenase; Provisional
Isocitrate/isopropylmalate dehydrogenase; cl00445
tartrate dehydrogenase; Provisional
Isocitrate/isopropylmalate dehydrogenase; cl00445
tartrate dehydrogenase; Provisional
Colier/Olf/Early B-cell factor (EBF) DNA Binding Domain; cd11606
IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved...; cd01175
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
M14 family of metallocarboxypeptidases and related proteins; cl11393
M14 family of metallocarboxypeptidases and related proteins; cl11393
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; cd11308
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Peptidase M14 carboxypeptidase subfamily N/E-like; Carboxypeptidase X subgroup; cd03869
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; cd11308
SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site...; cd01842
SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site...; cd01842
Vps16, N-terminal region; pfam04841
Vps16, C-terminal region; pfam04840
Vps16, N-terminal region; pfam04841
Vps16, C-terminal region; pfam04840
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Neurohypophysial hormones, C-terminal Domain; pfam00184
Neurohypophysial hormones; smart00003
U-box domain; pfam04564
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
U-box domain; pfam04564
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
U-box domain; pfam04564
FAST kinase-like protein, subdomain 1; pfam06743
FAST kinase-like protein, subdomain 2; pfam08368
This domain is found in various eukaryotic species, particularly in apicomplexans; smart00952
Fez1; pfam06818
DDRGK domain; pfam09756
NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; cd00515
NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; cd00515
NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; cd00515
PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; cl00163
HCO3- transporter family; pfam00955
PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; cl00163
HCO3- transporter family; pfam00955
PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; cl00163
HCO3- transporter family; pfam00955
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Kelch motif; pfam01344
Kelch motif; pfam13854
Galactose oxidase, central domain; cl02701
Plexin repeat; cl02601
C-type lectin-like domain (CTLD) of the type found in human and mouse attractin (AtrN) and attractin-like protein (ALP); cd03597
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Kelch motif; pfam01344
Kelch motif; pfam13854
Galactose oxidase, central domain; pfam13418
Plexin repeat; cl02601
C-type lectin-like domain (CTLD) of the type found in human and mouse attractin (AtrN) and attractin-like protein (ALP); cd03597
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Kelch motif; pfam01344
Kelch motif; pfam13854
Galactose oxidase, central domain; cl02701
Plexin repeat; cl02601
C-type lectin-like domain (CTLD) of the type found in human and mouse attractin (AtrN) and attractin-like protein (ALP); cd03597
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
GDNF/GAS1 domain; smart00907
GDNF/GAS1 domain; pfam02351
GDNF/GAS1 domain; smart00907
GDNF/GAS1 domain; smart00907
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family; cd04269
Disintegrin; pfam00200
ADAM Cysteine-Rich Domain; smart00608
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family; cd04269
Disintegrin; pfam00200
ADAM Cysteine-Rich Domain; smart00608
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
CD80-like C2-set immunoglobulin domain; pfam08205
Immunoglobulin domain; pfam13895
Immunoglobulin domain; pfam13895
Immunoglobulin domain; cd00096
Immunoglobulin domain; pfam13895
Immunoglobulin; smart00409
Immunoglobulin domain; pfam13895
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; pfam13895
Immunoglobulin domain; cd00096
Immunoglobulin domain; pfam13895
Immunoglobulin; smart00409
Immunoglobulin domain; pfam13895
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin; smart00409
Nucleotide-binding domain of HSPA12B and similar proteins; cd11736
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cl17037
Domain of Unknown Function (DUF1042); pfam06294
CENP-B N-terminal DNA-binding domain; pfam04218
Putative DNA-binding domain in centromere protein B, mouse jerky and transposases; smart00674
DDE superfamily endonuclease; pfam03184
Centromere protein B dimerisation domain; pfam09026
M-phase inducer phosphatase; pfam06617
Cdc25 phosphatases are members of the Rhodanese Homology Domain superfamily. They activate the cell division kinases throughout the cell cycle progression. Cdc25 phosphatases dephosphorylate phosphotyrosine and phosphothreonine residues, in order to...; cd01530
M-phase inducer phosphatase; pfam06617
Cdc25 phosphatases are members of the Rhodanese Homology Domain superfamily. They activate the cell division kinases throughout the cell cycle progression. Cdc25 phosphatases dephosphorylate phosphotyrosine and phosphothreonine residues, in order to...; cd01530
M-phase inducer phosphatase; pfam06617
Cdc25 phosphatases are members of the Rhodanese Homology Domain superfamily. They activate the cell division kinases throughout the cell cycle progression. Cdc25 phosphatases dephosphorylate phosphotyrosine and phosphothreonine residues, in order to...; cd01530
Caspase activation and recruitment domain (CARD) found in IPS-1; cd08811
Fumble; pfam03630
pantothenate kinase, eukaryotic/staphyloccocal type; TIGR00555
Fumble; pfam03630
Fumble; pfam03630
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
polyamine oxidase
NAD(P)-binding Rossmann-like domain; pfam13450
polyamine oxidase
NAD(P)-binding Rossmann-like domain; pfam13450
polyamine oxidase
NAD(P)-binding Rossmann-like domain; pfam13450
polyamine oxidase
NAD(P)-binding Rossmann-like domain; pfam13450
NAD(P)-binding Rossmann-like domain; pfam13450
7 transmembrane receptor (rhodopsin family); pfam00001
Major prion protein bPrPp - N terminal; pfam11587
Major prion protein; smart00157
Major prion protein bPrPp - N terminal; pfam11587
Major prion protein; smart00157
Major prion protein bPrPp - N terminal; pfam11587
Major prion protein; smart00157
Major prion protein bPrPp - N terminal; pfam11587
Major prion protein; smart00157
Major prion protein bPrPp - N terminal; pfam11587
Major prion protein; smart00157
Prion-like protein Doppel; pfam11466
Prion/Doppel alpha-helical domain; pfam00377
Ubiquitin-like domain of Rasfadin; cd01784
Ubiquitin-like domain of Rasfadin; cd01784
Permease family; pfam00860
Permease family; pfam00860
Eukaryotic protein of unknown function (DUF872); pfam05915
Eukaryotic protein of unknown function (DUF872); pfam05915
Eukaryotic protein of unknown function (DUF872); pfam05915
Eukaryotic protein of unknown function (DUF872); pfam05915
proliferating cell nuclear antigen (pcna); TIGR00590
Proliferating Cell Nuclear Antigen (PCNA) domain found in eukaryotes and archaea.  These polymerase processivity factors play a role in DNA replication and repair.  PCNA encircles duplex DNA in its central cavity, providing a DNA-bound platform for the...; cd00577
proliferating cell nuclear antigen (pcna); TIGR00590
Proliferating Cell Nuclear Antigen (PCNA) domain found in eukaryotes and archaea.  These polymerase processivity factors play a role in DNA replication and repair.  PCNA encircles duplex DNA in its central cavity, providing a DNA-bound platform for the...; cd00577
Cytidylyltransferase family; cl00347
7 transmembrane receptor (rhodopsin family); pfam00001
Prei4, N-terminal CBM20 (carbohydrate-binding module, family 20) domain. Preimplantation protein 4 (Prei4) is a protein of unknown function that is expressed during mouse preimplantation embryogenesis. In addition to the N-terminal CBM20 domain, Prei4...; cd05814
Glycerophosphodiester phosphodiesterase domain of putative mammalian glycerophosphodiester phosphodiesterase GDE5 and similar proteins; cd08607
Glycerophosphoryl diester phosphodiesterase family; pfam03009
Granin (chromogranin or secretogranin); pfam01271
Gcd10p family; pfam04189
minichromosome maintenance proteins; smart00350
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
minichromosome maintenance proteins; smart00350
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
CDP-alcohol phosphatidyltransferase; cl00453
CDP-alcohol phosphatidyltransferase; cl00453
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Band 4.1 homologues; smart00295
FERM central domain; pfam00373
Pleckstrin homology-like domain; cl00273
FERM central domain; pfam00373
TGF-beta propeptide; pfam00688
Transforming growth factor-beta (TGF-beta) family; smart00204
Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; cd02809
FMN-dependent dehydrogenase; pfam01070
PDIa family, TMX subfamily; composed of proteins similar to the TRX-related human transmembrane protein, TMX. TMX is a type I integral membrane protein; the N-terminal redox active TRX domain is present in the endoplasmic reticulum (ER) lumen while the...; cd02994
Phospholipase C (PLC) pleckstrin homology (PH) domain; cd01248
Phosphoinositide-specific phospholipase C, efhand-like; pfam09279
Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta; cd08591
Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; cl14615
C2 domain present in Phosphoinositide-specific phospholipases C (PLC); cd00275
Protein of unknown function (DUF1154); pfam06631
PLC-beta C terminal; pfam08703
Phospholipase C (PLC) pleckstrin homology (PH) domain; cd01248
Phosphoinositide-specific phospholipase C, efhand-like; pfam09279
Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta; cd08591
Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; cl14615
C2 domain present in Phosphoinositide-specific phospholipases C (PLC); cd00275
Protein of unknown function (DUF1154); pfam06631
PLC-beta C terminal; pfam08703
Phospholipase C (PLC) pleckstrin homology (PH) domain; cd01248
Phosphoinositide-specific phospholipase C, efhand-like; pfam09279
Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta; cd08591
Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; cl14615
C2 domain present in Phosphoinositide-specific phospholipases C (PLC); cd00275
Membrane-bound metallopeptidase [Cell division and chromosome partitioning]
Protein of unknown function (DUF1154); pfam06631
PLC-beta C terminal; pfam08703
Phospholipase C (PLC) pleckstrin homology (PH) domain; cd01248
Phosphoinositide-specific phospholipase C, efhand-like; pfam09279
Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta; cd08591
Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; cl14615
C2 domain present in Phosphoinositide-specific phospholipases C (PLC); cd00275
Membrane-bound metallopeptidase [Cell division and chromosome partitioning]
Protein of unknown function (DUF1154); pfam06631
PLC-beta C terminal; pfam08703
Phospholipase C (PLC) pleckstrin homology (PH) domain; cd01248
Phosphoinositide-specific phospholipase C, efhand-like; pfam09279
Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta; cd08591
Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; cl14615
C2 domain present in Phosphoinositide-specific phospholipases C (PLC); cd00275
Membrane-bound metallopeptidase [Cell division and chromosome partitioning]
Protein of unknown function (DUF1154); pfam06631
PLC-beta C terminal; pfam08703
Lysosome-associated membrane glycoprotein (Lamp); pfam01299
Lysosome-associated membrane glycoprotein (Lamp); pfam01299
PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the...; cd01093
Catalytic domain of the Protein Serine/Threonine Kinase, Group II p21-activated kinase; cd06648
Serine/Threonine protein kinases, catalytic domain; smart00220
PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the...; cd01093
Catalytic domain of the Protein Serine/Threonine Kinase, Group II p21-activated kinase; cd06648
Serine/Threonine protein kinases, catalytic domain; smart00220
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in...; cd00193
SNAP-25 family; pfam00835
Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in...; cd00193
Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in...; cd00193
SNAP-25 family; pfam00835
Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in...; cd00193
TCP-1/cpn60 chaperonin family; pfam00118
chaperonin_like superfamily. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. There are 2 main chaperonin groups. The symmetry of type I...; cl02777
TCP-1/cpn60 chaperonin family; pfam00118
chaperonin_like superfamily. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. There are 2 main chaperonin groups. The symmetry of type I...; cl02777
N terminus of Notch ligand; pfam07657
Delta serrate ligand; pfam01414
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
von Willebrand factor (vWF) type C domain; smart00215
BTB/POZ domain; pfam00651
BTB And C-terminal Kelch; smart00875
PHR domain; pfam08005
BTB/POZ domain; pfam00651
BTB And C-terminal Kelch; smart00875
PHR domain; pfam08005
7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; COG0156
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); cd06454
Thrombospondin type 1 repeats; smart00209
AMOP domain; pfam03782
Taspase1_like domains; Taspase1 catalyzes the cleavage of the mix lineage leukemia (MLL) nuclear protein and transcription factor TFIIA. Taspase1 is a threonine aspartase, a member of the Ntn hydrolase superfamily and the type 2 asparaginase family. A...; cd04514
Uncharacterized conserved protein [Function unknown]
NUC153 domain; pfam08159
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
Methyltransferase domain; pfam13489
Methyltransferase domain; pfam13489
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
FOG: TPR repeat, SEL1 subfamily [General function prediction only]
Sel1-like repeats; smart00671
FOG: TPR repeat, SEL1 subfamily [General function prediction only]
Sel1 repeat; cl02723
Sel1-like repeats; smart00671
Macro domain, Appr-1'-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose...; cd02908
Uncharacterized protein family UPF0560; pfam10577
Leucine rich repeat N-terminal domain; smart00013
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
Leucine rich repeat N-terminal domain; smart00013
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
Uncharacterized protein family UPF0560; pfam10577
Kinesin motor domain, KIF1_like proteins. KIF1A (Unc104) transports synaptic vesicles to the nerve terminal, KIF1B has been implicated in transport of mitochondria. Both proteins are expressed in neurons. This catalytic (head) domain has ATPase activity...; cd01365
Kinesin motor, catalytic domain. ATPase; smart00129
FHA domain; pfam00498
The phosphoinositide binding Phox Homology domain of KIF16B kinesin or Sorting Nexin 23; cd06874
Kinesin motor domain, KIF1_like proteins. KIF1A (Unc104) transports synaptic vesicles to the nerve terminal, KIF1B has been implicated in transport of mitochondria. Both proteins are expressed in neurons. This catalytic (head) domain has ATPase activity...; cd01365
Kinesin motor, catalytic domain. ATPase; smart00129
FHA domain; pfam00498
The phosphoinositide binding Phox Homology domain of KIF16B kinesin or Sorting Nexin 23; cd06874
Kinesin motor domain, KIF1_like proteins. KIF1A (Unc104) transports synaptic vesicles to the nerve terminal, KIF1B has been implicated in transport of mitochondria. Both proteins are expressed in neurons. This catalytic (head) domain has ATPase activity...; cd01365
Kinesin motor, catalytic domain. ATPase; smart00129
FHA domain; pfam00498
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Melanoma Inhibitory Activity-Like protein; cd11891
Peptidase S8 family domain in Protein convertases; cd04059
Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; COG1404
Proprotein convertase P-domain; pfam01483
Peptidase S8 family domain in Protein convertases; cd04059
Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; COG1404
Proprotein convertase P-domain; pfam01483
Peptidase S8 family domain in Protein convertases; cd04059
Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; COG1404
Proprotein convertase P-domain; pfam01483
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
Intermediate filament protein; pfam00038
Cofilin, Destrin, and related actin depolymerizing factors; cd11286
Cofilin, Destrin, and related actin depolymerizing factors; cd11286
Ribosome receptor lysine/proline rich region; pfam05104
Ribosome receptor lysine/proline rich region; pfam05104
Barrier to autointegration factor; cl03803
Barrier to autointegration factor; cl03803
Barrier to autointegration factor; cl03803
The phosphoinositide binding Phox Homology domain of Sorting Nexin 5; cd07291
Vps5 C terminal like; pfam09325
The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 5; cd07663
The phosphoinositide binding Phox Homology domain of Sorting Nexin 5; cd07291
Vps5 C terminal like; pfam09325
The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 5; cd07663
CRISPR/Cas system-associated protein Cas4; cl00641
Zinc-finger double domain; pfam13465
Acetyltransferase (GNAT) domain; pfam13673
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; cd04301
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Chitobiase/beta-hexosaminidase C-terminal domain; pfam03174
Double zinc ribbon; pfam12773
Double zinc ribbon; pfam12773
zinc-ribbon domain; pfam13248
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
RNA polymerase Rpc34 subunit; pfam05158
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
transport protein sec23; Provisional
Sec23/Sec24 zinc finger; pfam04810
Sec23-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the budding and fusion of intracellular transport vesicles that selectively carry cargo proteins and lipids from donor to acceptor organelles. The two main classes...; cd01478
Sec23/Sec24 beta-sandwich domain; pfam08033
Sec23/Sec24 helical domain; pfam04815
C-terminal Actin depolymerization factor-homology domain of Sec23; cd11287
transport protein sec23; Provisional
Sec23/Sec24 zinc finger; pfam04810
Sec23-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the budding and fusion of intracellular transport vesicles that selectively carry cargo proteins and lipids from donor to acceptor organelles. The two main classes...; cd01478
Sec23/Sec24 beta-sandwich domain; pfam08033
Sec23/Sec24 helical domain; pfam04815
C-terminal Actin depolymerization factor-homology domain of Sec23; cd11287
transport protein sec23; Provisional
Sec23/Sec24 zinc finger; pfam04810
Sec23-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the budding and fusion of intracellular transport vesicles that selectively carry cargo proteins and lipids from donor to acceptor organelles. The two main classes...; cd01478
Sec23/Sec24 beta-sandwich domain; pfam08033
Sec23/Sec24 helical domain; pfam04815
C-terminal Actin depolymerization factor-homology domain of Sec23; cd11287
transport protein sec23; Provisional
Sec23/Sec24 zinc finger; pfam04810
Sec23-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the budding and fusion of intracellular transport vesicles that selectively carry cargo proteins and lipids from donor to acceptor organelles. The two main classes...; cd01478
Sec23/Sec24 beta-sandwich domain; pfam08033
Sec23/Sec24 helical domain; pfam04815
C-terminal Actin depolymerization factor-homology domain of Sec23; cd11287
transport protein sec23; Provisional
Sec23/Sec24 zinc finger; pfam04810
Sec23-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the budding and fusion of intracellular transport vesicles that selectively carry cargo proteins and lipids from donor to acceptor organelles. The two main classes...; cd01478
Sec23/Sec24 beta-sandwich domain; pfam08033
Sec23/Sec24 helical domain; pfam04815
C-terminal Actin depolymerization factor-homology domain of Sec23; cd11287
D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; cd00563
SCP-2 sterol transfer family; pfam02036
Sodium/calcium exchanger protein; pfam01699
Sodium/calcium exchanger protein; pfam01699
Src homology 2 (SH2) domain found in Ras and Rab interactor 2 (RIN2)-like proteins; cd10394
Domain present in VPS9; smart00167
Ubiquitin domain of RIN1 RAS effector; cd01776
Src homology 2 (SH2) domain found in Ras and Rab interactor 2 (RIN2)-like proteins; cd10394
Domain present in VPS9; smart00167
Ubiquitin domain of RIN1 RAS effector; cd01776
Acetyltransferases [General function prediction only]; COG0456
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; cd04301
Acetyltransferases [General function prediction only]; COG0456
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; cd04301
Acetyltransferases [General function prediction only]; COG0456
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; cd04301
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
HAT (Half-A-TPR) repeat; pfam02184
HAT (Half-A-TPR) repeats; smart00386
HAT (Half-A-TPR) repeats; smart00386
NAD(P)H-nitrite reductase [Energy production and conversion]; COG1251
Rap/ran-GAP; pfam02145
XRN 5'-3' exonuclease N-terminus; pfam03159
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Paired Box domain; cd00131
'Paired box' domain; pfam00292
Paired Box domain; cd00131
'Paired box' domain; pfam00292
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
HNF3 C-terminal domain; pfam09354
Forkhead N-terminal region; pfam08430
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
HNF3 C-terminal domain; pfam09354
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
C-type lectin-like domain (CTLD) of the type found in human thrombomodulin(TM), Endosialin, C14orf27, and C1qR; cd03600
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain; smart00179
Thrombomodulin like fifth domain, EGF-like; pfam09064
Calcium-binding EGF-like domain; smart00179
C-type lectin-like domain (CTLD) of the type found in human thrombomodulin(TM), Endosialin, C14orf27, and C1qR; cd03600
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF domain; pfam07645
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many...; cd00780
BTB/POZ domain; pfam00651
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains; cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains; cl09238
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains; cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains; cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains; cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains; cl09238
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains; cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains; cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains; cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains; cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains; cd00042
Gamma-glutamyltransferase [Amino acid transport and metabolism]; cl08040
Gamma-glutamyltransferase [Amino acid transport and metabolism]; cl08040
Interferon-induced transmembrane protein; pfam04505
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains; cd00042
Gluconolactonase [Carbohydrate transport and metabolism]
Strictosidine synthase; pfam03088
Domain of unknown function (DUF3448); pfam11930
AMP-binding enzyme; pfam00501
acetate--CoA ligase; TIGR02188
Domain of unknown function (DUF3448); pfam11930
AMP-binding enzyme; pfam00501
Domain of unknown function (DUF4009); pfam13193
acetate--CoA ligase; TIGR02188
Domain of unknown function (DUF3448); pfam11930
AMP-binding enzyme; pfam00501
Domain of unknown function (DUF4009); pfam13193
Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; COG0365
AMP-binding enzyme; pfam00501
Domain of unknown function (DUF4009); pfam13193
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; cd04300
glycogen/starch/alpha-glucan phosphorylases; TIGR02093
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Alpha/beta hydrolase family; pfam12695
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Alpha/beta hydrolase family; pfam12695
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Alpha-helical domain of GINS complex protein Psf1; cd11710
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
HAD superfamily (subfamily IA) hydrolase, TIGR02253
Haloacid Dehalogenase-like Hydrolases; cl11391
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Beta defensin; pfam13841
Beta defensin; pfam13841
Beta defensin; pfam13841
Beta defensin; pfam13841
Beta defensin; pfam13841
Beta defensin; pfam13841
Beta defensin; pfam13841
Beta defensin; pfam13841
Beta defensin; pfam13841
Beta defensin; pfam13841
Rem, Rem2, Rad, Gem/Kir (RGK) subfamily of Ras GTPases; cd04148
Signal peptide peptidase; pfam04258
Signal peptide peptidase; pfam04258
Signal peptide peptidase; pfam04258
Signal peptide peptidase; cl01342
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Cytochrome c oxidase subunit IV. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; cd00922
apoptosis regulator; TIGR00865
Bcl-2 homology region 4; pfam02180
Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane...; cl02575
apoptosis regulator; TIGR00865
Bcl-2 homology region 4; pfam02180
Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane...; cd06845
Aurora-A binding; pfam09041
Cell cycle regulated microtubule associated protein; pfam12214
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cl00053
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cl00053
Tubulin-tyrosine ligase family; pfam03133
Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta subunits, the two subunits...; cl09111
Src homology 3 domain of Src kinase-like Protein Tyrosine Kinases; cd11845
Src homology 2 (SH2) domain found in HCK; cd10363
Catalytic domain of Src kinase-like Protein Tyrosine Kinases; cd05034
Protein tyrosine kinase; pfam07714
Src homology 3 domain of Src kinase-like Protein Tyrosine Kinases; cd11845
Src homology 2 (SH2) domain found in HCK; cd10363
Catalytic domain of Src kinase-like Protein Tyrosine Kinases; cd05034
Protein tyrosine kinase; pfam07714
Src homology 3 domain of Src kinase-like Protein Tyrosine Kinases; cd11845
Src homology 2 (SH2) domain found in HCK; cd10363
Catalytic domain of Src kinase-like Protein Tyrosine Kinases; cd05034
Protein tyrosine kinase; pfam07714
Src homology 3 domain of Src kinase-like Protein Tyrosine Kinases; cd11845
Src homology 2 (SH2) domain found in HCK; cd10363
Catalytic domain of Src kinase-like Protein Tyrosine Kinases; cd05034
Protein tyrosine kinase; pfam07714
Src homology 3 domain of Src kinase-like Protein Tyrosine Kinases; cd11845
Src homology 2 (SH2) domain found in HCK; cd10363
Catalytic domain of Src kinase-like Protein Tyrosine Kinases; cd05034
Protein tyrosine kinase; pfam07714
Src homology 3 domain of Src kinase-like Protein Tyrosine Kinases; cd11845
Src homology 2 (SH2) domain found in HCK; cd10363
Catalytic domain of Src kinase-like Protein Tyrosine Kinases; cd05034
Protein tyrosine kinase; pfam07714
Endomembrane protein 70; pfam02990
Zinc-finger double domain; pfam13465
GDP-fucose protein O-fucosyltransferase 1; cd11302
GDP-fucose protein O-fucosyltransferase; pfam10250
GDP-fucose protein O-fucosyltransferase and related proteins; cl16914
Kinesin motor, catalytic domain. ATPase; smart00129
Kinesin motor domain, kinesins II or KIF3_like proteins. Subgroup of kinesins, which form heterotrimers composed of 2 kinesins and one non-motor accessory subunit. Kinesins II play important roles in ciliary transport, and have been implicated in...; cd01371
Transcriptional enhancer, Asx-hm domain; pfam13919
PHD domain of transcriptional enhancer, Asx; pfam13922
COMM_Domain containing protein 7. The COMM Domain is found at the C-terminus of a variety of proteins; presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in protein-protein interactions. Several...; cd04755
COMM_Domain containing protein 7. The COMM Domain is found at the C-terminus of a variety of proteins; presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in protein-protein interactions. Several...; cd04755
The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis.  In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in...; cd05835
ADDz domain of DNA (cytosine-5) methyltransferases (C5-MTases) 3 b (Dnmt3b); cd11728
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
Site-specific DNA methylase [DNA replication, recombination, and repair]; COG0270
The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis.  In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in...; cd05835
ADDz domain of DNA (cytosine-5) methyltransferases (C5-MTases) 3 b (Dnmt3b); cd11728
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
Site-specific DNA methylase [DNA replication, recombination, and repair]; COG0270
The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis.  In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in...; cd05835
ADDz domain of DNA (cytosine-5) methyltransferases (C5-MTases) 3 b (Dnmt3b); cd11728
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
Site-specific DNA methylase [DNA replication, recombination, and repair]; COG0270
The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis.  In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in...; cd05835
ADDz domain of DNA (cytosine-5) methyltransferases (C5-MTases) 3 b (Dnmt3b); cd11728
Site-specific DNA methylase [DNA replication, recombination, and repair]; COG0270
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis.  In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in...; cd05835
ADDz domain of DNA (cytosine-5) methyltransferases (C5-MTases) 3 b (Dnmt3b); cd11728
Site-specific DNA methylase [DNA replication, recombination, and repair]; COG0270
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis.  In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in...; cd05835
ADDz domain of DNA (cytosine-5) methyltransferases (C5-MTases) 3 b (Dnmt3b); cd11728
Site-specific DNA methylase [DNA replication, recombination, and repair]; COG0270
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
Calponin homology (CH) domain; pfam00307
EB1-like C-terminal motif; pfam03271
Sad1 / UNC-like C-terminal; pfam07738
LBP / BPI / CETP family, N-terminal domain; pfam01273
BPI/LBP/CETP C-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) C-terminal domain; binds to and neutralizes lipopolysaccharides from the outer...; cd00026
BPI/LBP/CETP N-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) N-terminal domain; binds to and neutralizes lipopolysaccharides from the outer...; cd00025
BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative...; cl00188
BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative...; cl00188
BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative...; cl00188
BPI/LBP/CETP N-terminal domain; smart00328
BPI/LBP/CETP C-terminal domain; smart00329
LBP / BPI / CETP family, N-terminal domain; pfam01273
LBP / BPI / CETP family, N-terminal domain; pfam01273
BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative...; cl00188
LBP / BPI / CETP family, N-terminal domain; pfam01273
LBP / BPI / CETP family, N-terminal domain; pfam01273
LBP / BPI / CETP family, N-terminal domain; pfam01273
BPI/LBP/CETP N-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) N-terminal domain; binds to and neutralizes lipopolysaccharides from the outer...; cd00025
BPI/LBP/CETP C-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) C-terminal domain; binds to and neutralizes lipopolysaccharides from the outer...; cd00026
(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional
Uncharacterized protein family UPF0004; pfam00919
TRAM domain; pfam01938
(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional
Uncharacterized protein family UPF0004; pfam00919
TRAM domain; pfam01938
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Pleckstrin homology-like domain; cl00273
NHR1 homology to TAF; pfam07531
NHR2 domain like; pfam08788
MYND finger; pfam01753
NHR1 homology to TAF; pfam07531
NHR2 domain like; pfam08788
MYND finger; pfam01753
NHR1 homology to TAF; pfam07531
NHR2 domain like; pfam08788
MYND finger; pfam01753
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Antibiotic biosynthesis monooxygenase; pfam03992
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Antibiotic biosynthesis monooxygenase; pfam03992
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cl17037
E2F/DP family winged-helix DNA-binding domain; pfam02319
Tim17/Tim22/Tim23/Pmp24 family; pfam02466
Tim17/Tim22/Tim23/Pmp24 family; pfam02466
C2H2-type zinc finger; pfam13912
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Snf7; pfam03357
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Domain found in IF2B/IF5; pfam01873
Agouti protein; cl04902
S-adenosyl-L-homocysteine hydrolase; Provisional
S-adenosyl-L-homocysteine hydrolase (AdoHycase) catalyzes the hydrolysis of S-adenosyl-L-homocysteine (AdoHyc) to form adenosine (Ado) and homocysteine (Hcy). The equilibrium lies far on the side of AdoHyc synthesis, but in nature the removal of Ado and...; cd00401
S-adenosyl-L-homocysteine hydrolase; Provisional
S-adenosyl-L-homocysteine hydrolase (AdoHycase) catalyzes the hydrolysis of S-adenosyl-L-homocysteine (AdoHyc) to form adenosine (Ado) and homocysteine (Hcy). The equilibrium lies far on the side of AdoHyc synthesis, but in nature the removal of Ado and...; cd00401
C2 domain present in E3 ubiquitin ligase; cd04021
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
C2 domain present in E3 ubiquitin ligase; cd04021
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
C2 domain; cl14603
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
Roadblock/LC7 domain; smart00960
Ubiquitin domain of GABA-receptor-associated protein; cd01611
Ubiquitin domain of GABA-receptor-associated protein; cd01611
GPI transamidase subunit PIG-U; pfam06728
Putative nucleic acid-binding region; pfam13820
Putative nucleic acid-binding region; pfam13820
Gamma-glutamyltransferase [Amino acid transport and metabolism]; cl08040
Gamma-glutamyltranspeptidase; pfam01019
acetyl-CoA synthetase; Provisional
Domain of unknown function (DUF3448); pfam11930
AMP-binding enzyme; pfam00501
Domain of unknown function (DUF4009); pfam13193
acetyl-CoA synthetase; Provisional
Domain of unknown function (DUF3448); pfam11930
AMP-binding enzyme; pfam00501
Domain of unknown function (DUF4009); pfam13193
acetate--CoA ligase; TIGR02188
Domain of unknown function (DUF3448); pfam11930
AMP-binding enzyme; pfam00501
Domain of unknown function (DUF4009); pfam13193
Eukaryotic Glutathione Synthetase (eu-GS); catalyses the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner. Belongs to the ATP-grasp superfamily; cd00228
Myosin N-terminal SH3-like domain; pfam02736
Myosin. Large ATPases; smart00242
Myosin motor domain, type II myosins. Myosin II mediates cortical contraction in cell motility, and is the motor in smooth and skeletal muscle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins...; cd01377
Myosin tail; pfam01576
Protein of unknown function (DUF3689); pfam12463
Protein of unknown function (DUF3689); pfam12463
Glycosyl hydrolase family 47; pfam01532
Glycosyl hydrolase family 47; pfam01532
Class I Histocompatibility antigen, domains alpha 1 and 2; pfam00129
Putative peptidoglycan binding domain; pfam01471
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate...; cd04278
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
Domain of unknown function (DUF3377); pfam11857
Ribosome anti-association factor IF6 binds the large ribosomal subunit and prevents the two subunits from associating during translation initiation. IF6 comprises a family of translation factors that includes both eukaryotic (eIF6) and archeal (aIF6)...; cd00527
Ribosome anti-association factor IF6 binds the large ribosomal subunit and prevents the two subunits from associating during translation initiation. IF6 comprises a family of translation factors that includes both eukaryotic (eIF6) and archeal (aIF6)...; cd00527
Ribosome anti-association factor IF6 binds the large ribosomal subunit and prevents the two subunits from associating during translation initiation. IF6 comprises a family of translation factors that includes both eukaryotic (eIF6) and archeal (aIF6)...; cd00527
Ribosome anti-association factor IF6 binds the large ribosomal subunit and prevents the two subunits from associating during translation initiation. IF6 comprises a family of translation factors that includes both eukaryotic (eIF6) and archeal (aIF6)...; cd00527
Protein of unknown function (DUF1669); pfam07894
N-terminal phospholipase D-like domain of the uncharacterized protein, Family with sequence similarity 83C; cd09183
Ubiquinol-cytochrome C chaperone; pfam03981
Ubiquinol-cytochrome C chaperone; pfam03981
Ubiquinol-cytochrome C chaperone; pfam03981
TGF-beta propeptide; pfam00688
Transforming growth factor-beta (TGF-beta) family; smart00204
chromosome segregation protein SMC, common bacterial type; TIGR02168
chromosome segregation protein SMC, common bacterial type; TIGR02168
chromosome segregation protein SMC, common bacterial type; TIGR02168
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC); pfam13850
Endoplasmic reticulum vesicle transporter; pfam07970
Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC); pfam13850
Endoplasmic reticulum vesicle transporter; pfam07970
Sad1 / UNC-like C-terminal; pfam07738
C2 domain first repeat in Copine; cd04048
C2 domain second repeat in Copine; cd04047
VWA Copine: Copines are phospholipid-binding proteins originally identified in paramecium. They are found in human and orthologues have been found in C. elegans and Arabidopsis Thaliana. None have been found in D. Melanogaster or S. Cereviciae; cd01459
C2 domain first repeat in Copine; cd04048
C2 domain second repeat in Copine; cd04047
VWA Copine: Copines are phospholipid-binding proteins originally identified in paramecium. They are found in human and orthologues have been found in C. elegans and Arabidopsis Thaliana. None have been found in D. Melanogaster or S. Cereviciae; cd01459
C2 domain first repeat in Copine; cd04048
C2 domain second repeat in Copine; cd04047
VWA Copine: Copines are phospholipid-binding proteins originally identified in paramecium. They are found in human and orthologues have been found in C. elegans and Arabidopsis Thaliana. None have been found in D. Melanogaster or S. Cereviciae; cd01459
C2 domain first repeat in Copine; cd04048
C2 domain second repeat in Copine; cd04047
VWA Copine: Copines are phospholipid-binding proteins originally identified in paramecium. They are found in human and orthologues have been found in C. elegans and Arabidopsis Thaliana. None have been found in D. Melanogaster or S. Cereviciae; cd01459
C2 domain first repeat in Copine; cd04048
C2 domain second repeat in Copine; cd04047
VWA Copine: Copines are phospholipid-binding proteins originally identified in paramecium. They are found in human and orthologues have been found in C. elegans and Arabidopsis Thaliana. None have been found in D. Melanogaster or S. Cereviciae; cd01459
C2 domain first repeat in Copine; cd04048
C2 domain second repeat in Copine; cd04047
VWA Copine: Copines are phospholipid-binding proteins originally identified in paramecium. They are found in human and orthologues have been found in C. elegans and Arabidopsis Thaliana. None have been found in D. Melanogaster or S. Cereviciae; cd01459
RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); pfam14259
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); pfam14259
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); pfam14259
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA recognition motif (a.k.a. RRM, RBD, or RNP domain); pfam14259
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; cl00321
cysteine desulfurase DndA; TIGR03235
cysteine desulfurase; Provisional
cysteine desulfurase DndA; TIGR03235
Reactive mitochondrial oxygen species modulator 1; pfam10247
splicing factor, CC1-like family; TIGR01622
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
splicing factor, CC1-like family; TIGR01622
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
splicing factor, CC1-like family; TIGR01622
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
splicing factor, CC1-like family; TIGR01622
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cl15261
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
Protein of unknown function (DUF3776); pfam12618
PHD-finger; pfam00628
SCAN oligomerization domain; cl02605
SCAN oligomerization domain; cl02605
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
FERM adjacent (FA); pfam08736
SAB domain; pfam04382
4.1 protein C-terminal domain (CTD); pfam05902
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
FERM adjacent (FA); pfam08736
SAB domain; pfam04382
4.1 protein C-terminal domain (CTD); pfam05902
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
FERM adjacent (FA); pfam08736
SAB domain; pfam04382
4.1 protein C-terminal domain (CTD); pfam05902
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
FERM adjacent (FA); pfam08736
SAB domain; pfam04382
4.1 protein C-terminal domain (CTD); pfam05902
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
FERM adjacent (FA); pfam08736
SAB domain; pfam04382
4.1 protein C-terminal domain (CTD); pfam05902
AAR2 protein; pfam05282
Guanylate-kinase-associated protein (GKAP) protein; pfam03359
Guanylate-kinase-associated protein (GKAP) protein; pfam03359
Guanylate-kinase-associated protein (GKAP) protein; pfam03359
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13833
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Rab5-interacting protein (Rab5ip); pfam07019
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Rab5-interacting protein (Rab5ip); pfam07019
Rab5-interacting protein (Rab5ip); pfam07019
Rab5-interacting protein (Rab5ip); pfam07019
Src homology 3 domain of Src-Like Adaptor Protein 2; cd12011
Src homology 2 (SH2) domain; cl15255
Src Homology 3 domain superfamily; cl17036
Src homology 2 (SH2) domain; cl15255
Ndr family; pfam03096
Ndr family; pfam03096
Mis12-Mtw1 protein family; pfam08202
Mis12-Mtw1 protein family; pfam08202
Mis12-Mtw1 protein family; pfam08202
Mis12-Mtw1 protein family; pfam08202
Mis12-Mtw1 protein family; pfam08202
Protein of unknown function (DUF3166); pfam11365
Protein of unknown function (DUF3166); pfam11365
Protein of unknown function (DUF3166); pfam11365
Protein of unknown function (DUF3166); pfam11365
domain in TBC and LysM domain containing proteins; smart00584
SAM domain of HD-phosphohydrolase; cd09508
Sterile alpha motif; smart00454
HD superfamily phosphohydrolases [General function prediction only]
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Domain of unknown function (DUF3452); pfam11934
Retinoblastoma-associated protein A domain; pfam01858
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Rb C-terminal domain; pfam08934
Domain of unknown function (DUF3452); pfam11934
Retinoblastoma-associated protein A domain; pfam01858
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Rb C-terminal domain; pfam08934
Oligosaccharyltransferase subunit Ribophorin II; pfam05817
Oligosaccharyltransferase subunit Ribophorin II; pfam05817
Peptide hormone; pfam00123
Peptide hormone; pfam00123
Uncharacterized protein family (UPF0239); pfam06783
Uncharacterized protein family (UPF0239); pfam06783
Src homology 3 domain of Src Protein Tyrosine Kinase; cd12008
Src homology 2 (SH2) domain found in tyrosine kinase sarcoma (Src); cd10365
Catalytic domain of Src kinase-like Protein Tyrosine Kinases; cd05034
Protein tyrosine kinase; pfam07714
Src homology 3 domain of Src Protein Tyrosine Kinase; cd12008
Src homology 2 (SH2) domain found in tyrosine kinase sarcoma (Src); cd10365
Catalytic domain of Src kinase-like Protein Tyrosine Kinases; cd05034
Protein tyrosine kinase; pfam07714
Bladder cancer-related protein BC10; pfam06726
Bladder cancer-related protein BC10; pfam06726
Bladder cancer-related protein BC10; pfam06726
Bladder cancer-related protein BC10; pfam06726
Bladder cancer-related protein BC10; pfam06726
Eukaryotic domain of unknown function (DUF1716); pfam08216
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Immunoglobulin like; smart00410
CID (CTD-Interacting Domain) domain family; CID is present in several RNA-processing factors such as Pcf11 and Nrd1. Pcf11 is a conserved and essential subunit of the yeast cleavage factor IA, which is required for polyadenylation-dependent 3'-RNA...; cd03562
Transglutaminase family; pfam00868
Transglutaminase/protease-like homologues; smart00460
Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]
Transglutaminase family, C-terminal ig like domain; pfam00927
Transglutaminase family, C-terminal ig like domain; pfam00927
Transglutaminase family; pfam00868
Transglutaminase/protease-like homologues; smart00460
Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]
Transglutaminase family, C-terminal ig like domain; pfam00927
Divergent CRAL/TRIO domain; pfam13716
BPI/LBP/CETP N-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) N-terminal domain; binds to and neutralizes lipopolysaccharides from the outer...; cd00025
BPI/LBP/CETP C-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) C-terminal domain; binds to and neutralizes lipopolysaccharides from the outer...; cd00026
BPI/LBP/CETP N-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) N-terminal domain; binds to and neutralizes lipopolysaccharides from the outer...; cd00025
BPI/LBP/CETP C-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) C-terminal domain; binds to and neutralizes lipopolysaccharides from the outer...; cd00026
RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when...; cl02570
GTPase-activator protein for Rho-like GTPases; smart00324
Transmembrane amino acid transporter protein; pfam01490
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cl17037
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Protein of unknown function (DUF1669); pfam07894
N-terminal phospholipase D-like domain of the protein, Family with sequence similarity 83D; cd09184
DEAD-like helicases superfamily; smart00487
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Helicase associated domain (HA2); pfam04408
Oligonucleotide/oligosaccharide-binding (OB)-fold; pfam07717
HrpA-like helicases [DNA replication, recombination, and repair]; COG1643
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Helicase associated domain (HA2); pfam04408
Oligonucleotide/oligosaccharide-binding (OB)-fold; pfam07717
Maf N-terminal region; pfam08383
bZIP Maf transcription factor; pfam03131
Topoisomer_IB_N_htopoI_like : N-terminal DNA binding fragment found in eukaryotic DNA topoisomerase (topo) IB proteins similar to the monomeric yeast and human topo I.  Topo I enzymes are divided into:  topo type IA (bacterial) and type IB (eukaryotic); cd03488
DNA Topoisomerase I (eukaryota); smart00435
DNA topoisomerase IB, C-terminal catalytic domain. Topoisomerase I promotes the relaxation of both positive and negative DNA superhelical tension by introducing a transient single-stranded break in duplex DNA. This function is vital for the processes of...; cd00659
C-terminal topoisomerase domain; pfam14370
Phospholipase C (PLC) pleckstrin homology (PH) domain; cd01248
Phosphoinositide-specific phospholipase C, efhand-like; pfam09279
Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma; cd08592
N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma; cd10341
C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma; cd09932
Src homology 3 domain of Phospholipase C (PLC) gamma 1; cd11970
Pleckstrin homology (PH) domain; cd00821
Phosphatidylinositol-specific phospholipase C, Y domain; pfam00387
C2 domain present in Phosphoinositide-specific phospholipases C (PLC); cd00275
Phospholipase C (PLC) pleckstrin homology (PH) domain; cd01248
Phosphoinositide-specific phospholipase C, efhand-like; pfam09279
Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma; cd08592
N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma; cd10341
C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma; cd09932
Src homology 3 domain of Phospholipase C (PLC) gamma 1; cd11970
Pleckstrin homology (PH) domain; cd00821
Phosphatidylinositol-specific phospholipase C, Y domain; pfam00387
C2 domain present in Phosphoinositide-specific phospholipases C (PLC); cd00275
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain leucine-zipper encoding, Homez; pfam11569
lipin, N-terminal conserved region; pfam04571
LNS2 (Lipin/Ned1/Smp2); pfam08235
This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain and phosphatidylinositol transfer proteins; smart00775
EMI domain; pfam07546
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
BRK domain; cl02688
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Immunoglobulin domain; cl11960
Fibronectin type 3 domain; smart00060
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Immunoglobulin domain; cl11960
Fibronectin type 3 domain; smart00060
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Zinc finger, C2HC type; pfam01530
SAM (Sterile alpha motif ); cl15755
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Zinc finger, C2HC type; pfam01530
SAM (Sterile alpha motif ); cl15755
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, Serum- and Glucocorticoid-induced Kinase 2; cd05603
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, Serum- and Glucocorticoid-induced Kinase 2; cd05603
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, Serum- and Glucocorticoid-induced Kinase 2; cd05603
ABC-type uncharacterized transport system; pfam09822
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
C-myb, C-terminal; pfam09316
U11-48K-like CHHC zinc finger; pfam05253
U11-48K-like CHHC zinc finger; pfam05253
U11-48K-like CHHC zinc finger; pfam05253
U11-48K-like CHHC zinc finger; pfam05253
High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I...; cd00084
High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I...; cd00084
High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I...; cd00084
High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I...; cd00084
MORN repeat; pfam02493
MORN repeat; pfam02493
phosphatidylinositol phosphate kinase; Provisional
Protein of unknown function (DUF776); pfam05604
Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; COG0625
GST_N family, Ganglioside-induced differentiation-associated protein 1 (GDAP1) subfamily; GDAP1 was originally identified as a highly expressed gene at the differentiated stage of GD3 synthase-transfected cells. More recently, mutations in GDAP1 have...; cd03052
C-terminal, alpha helical domain of Ganglioside-induced differentiation-associated protein 1-like 1; cd10302
Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; COG0625
GST_N family, Ganglioside-induced differentiation-associated protein 1 (GDAP1) subfamily; GDAP1 was originally identified as a highly expressed gene at the differentiated stage of GD3 synthase-transfected cells. More recently, mutations in GDAP1 have...; cd03052
C-terminal, alpha helical domain of Ganglioside-induced differentiation-associated protein 1-like 1; cd10302
Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; COG0625
GST_N family, Ganglioside-induced differentiation-associated protein 1 (GDAP1) subfamily; GDAP1 was originally identified as a highly expressed gene at the differentiated stage of GD3 synthase-transfected cells. More recently, mutations in GDAP1 have...; cd03052
C-terminal, alpha helical domain of the Glutathione S-transferase family; cl02776
Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; COG0625
GST_N family, Ganglioside-induced differentiation-associated protein 1 (GDAP1) subfamily; GDAP1 was originally identified as a highly expressed gene at the differentiated stage of GD3 synthase-transfected cells. More recently, mutations in GDAP1 have...; cd03052
C-terminal, alpha helical domain of the Glutathione S-transferase family; cl02776
Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; cl00388
C-terminal, alpha helical domain of the Glutathione S-transferase family; cl02776
Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; COG0625
Inositol phospholipid synthesis and fat-storage-inducing TM; pfam10261
SCP: SCP-like extracellular protein domain, found in eukaryotes and prokaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), which accumulates after infections with pathogens, and may act as an anti-fungal agent or be involved in...; cl00133
DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers; cd06960
The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes; cd06931
DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers; cd06960
The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes; cd06931
DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers; cd06960
The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes; cd06931
DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers; cd06960
The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes; cd06931
DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers; cd06960
The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes; cd06931
DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers; cd06960
The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes; cd06931
DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers; cd06960
The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes; cd06931
CRAL/TRIO, N-terminal domain; smart01100
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
CRAL/TRIO, N-terminal domain; smart01100
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
CRAL/TRIO, N-terminal domain; smart01100
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
Serine incorporator (Serinc); pfam03348
Serine incorporator (Serinc); pfam03348
cAMP-dependent protein kinase inhibitor; pfam02827
cAMP-dependent protein kinase inhibitor; pfam02827
cAMP-dependent protein kinase inhibitor; pfam02827
Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; cd01320
Adenosine deaminase [Nucleotide transport and metabolism]; COG1816
Insulin-like growth factor binding protein; cl02472
von Willebrand factor type C domain; cl02515
Ion channel; pfam07885
Ion channel; pfam07885
C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins; cd04028
C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins; cd04028
14-3-3 beta and zeta isoforms of 14-3-3 protein; cd10022
14-3-3 beta and zeta isoforms of 14-3-3 protein; cd10022
polyadenylate binding protein, human types 1, 2, 3, 4 family; TIGR01628
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Poly-adenylate binding protein, unique domain; pfam00658
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Catalytic domain of the Protein Serine/Threonine Kinases, Mammalian Ste20-like protein kinase 1 and 2; cd06612
Serine/Threonine protein kinases, catalytic domain; smart00220
C terminal SARAH domain of Mst1; pfam11629
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of...; cd00199
WAP-type (Whey Acidic Protein) 'four-disulfide core'; pfam00095
Trappin protein transglutaminase binding domain; pfam10511
Trappin protein transglutaminase binding domain; pfam10511
whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of...; cd00199
Semenogelin; pfam05474
Semenogelin; pfam05474
WAP-type (Whey Acidic Protein) 'four-disulfide core'; pfam00095
whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of...; cd00199
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
VWA_Matrilin: In cartilaginous plate, extracellular matrix molecules mediate cell-matrix and matrix-matrix interactions thereby providing tissue integrity. Some members of the matrilin family are expressed specifically in developing cartilage rudiments; cd01475
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Complement Clr-like EGF-like; pfam12662
VWA_Matrilin: In cartilaginous plate, extracellular matrix molecules mediate cell-matrix and matrix-matrix interactions thereby providing tissue integrity. Some members of the matrilin family are expressed specifically in developing cartilage rudiments; cd01475
VWA_Matrilin: In cartilaginous plate, extracellular matrix molecules mediate cell-matrix and matrix-matrix interactions thereby providing tissue integrity. Some members of the matrilin family are expressed specifically in developing cartilage rudiments; cd01475
Calcium-binding EGF-like domain; smart00179
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
VWA_Matrilin: In cartilaginous plate, extracellular matrix molecules mediate cell-matrix and matrix-matrix interactions thereby providing tissue integrity. Some members of the matrilin family are expressed specifically in developing cartilage rudiments; cd01475
LAG1, DNA binding; pfam09271
Beta-trefoil DNA-binding domain; pfam09270
IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known...; cd01176
Syndecan domain; pfam01034
putative band 4.1 homologues' binding motif; smart00294
Integral membrane protein S linking to the trans Golgi network; pfam09801
Integral membrane protein S linking to the trans Golgi network; pfam09801
Integral membrane protein S linking to the trans Golgi network; pfam09801
Dysbindin (Dystrobrevin binding protein 1); pfam04440
Dysbindin (Dystrobrevin binding protein 1); pfam04440
Dysbindin (Dystrobrevin binding protein 1); pfam04440
Dysbindin (Dystrobrevin binding protein 1); pfam04440
Dysbindin (Dystrobrevin binding protein 1); pfam04440
Dysbindin (Dystrobrevin binding protein 1); pfam04440
Dysbindin (Dystrobrevin binding protein 1); pfam04440
Dysbindin (Dystrobrevin binding protein 1); pfam04440
Dysbindin (Dystrobrevin binding protein 1); pfam04440
Gpi16 subunit, GPI transamidase component; pfam04113
Gpi16 subunit, GPI transamidase component; pfam04113
Gpi16 subunit, GPI transamidase component; pfam04113
Gpi16 subunit, GPI transamidase component; pfam04113
Gpi16 subunit, GPI transamidase component; pfam04113
Gpi16 subunit, GPI transamidase component; pfam04113
WAP-type (Whey Acidic Protein) 'four-disulfide core'; pfam00095
whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of...; cd00199
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
WAP-type (Whey Acidic Protein) 'four-disulfide core'; pfam00095
whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of...; cl00156
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of...; cl00156
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of...; cd00199
whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of...; cl00156
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of...; cd00199
whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of...; cl00156
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
WAP-type (Whey Acidic Protein) 'four-disulfide core'; pfam00095
WAP-type (Whey Acidic Protein) 'four-disulfide core'; pfam00095
whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of...; cl00156
WAP-type (Whey Acidic Protein) 'four-disulfide core'; pfam00095
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cl00154
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
The Phox Homology domain, a phosphoinositide binding module; cl02563
The phosphoinositide binding Phox Homology domain of Sorting Nexin 21; cd07301
Tetratricopeptide repeat; pfam13424
The Phox Homology domain, a phosphoinositide binding module; cl02563
The Phox Homology domain, a phosphoinositide binding module; cl02563
acyl-CoA thioesterase II; TIGR00189
Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; cd03445
Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; cd03444
MULE transposase domain; pfam10551
SWIM zinc finger; pfam04434
SWIM zinc finger; pfam04434
Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) [Translation, ribosomal structure and biogenesis]; COG1185
Neuralized; cl02685
SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins...; cd03587
Serine carboxypeptidase; pfam00450
Serine carboxypeptidase; pfam00450
Serine carboxypeptidase; pfam00450
BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative...; cl00188
BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative...; cl00188
BPI/LBP/CETP C-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) C-terminal domain; binds to and neutralizes lipopolysaccharides from the outer...; cd00026
BPI/LBP/CETP N-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) N-terminal domain; binds to and neutralizes lipopolysaccharides from the outer...; cd00025
BPI/LBP/CETP C-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) C-terminal domain; binds to and neutralizes lipopolysaccharides from the outer...; cd00026
BPI/LBP/CETP N-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) N-terminal domain; binds to and neutralizes lipopolysaccharides from the outer...; cd00025
BPI/LBP/CETP C-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) C-terminal domain; binds to and neutralizes lipopolysaccharides from the outer...; cd00026
BPI/LBP/CETP N-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) N-terminal domain; binds to and neutralizes lipopolysaccharides from the outer...; cd00025
BPI/LBP/CETP C-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) C-terminal domain; binds to and neutralizes lipopolysaccharides from the outer...; cd00026
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Phosphorylated CTD interacting factor 1 WW domain; pfam12237
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate...; cd04278
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and...; cd00062
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and...; cd00062
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and...; cd00062
Matrixin; pfam00413
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
K-Cl cotransporter; TIGR00930
K-Cl cotransporter; TIGR00930
Histidyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; COG0124
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cl12111
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Tumor necrosis factor receptor / nerve growth factor receptor repeats; smart00208
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin cytoplasmic region; pfam01049
Triose-phosphate Transporter family; pfam03151
Triose-phosphate Transporter family; pfam03151
Triose-phosphate Transporter family; pfam03151
Domain of unknown function (DUF3361); pfam11841
ELMO/CED-12 family; pfam04727
Pleckstrin homology-like domain; cl00273
Domain of unknown function (DUF3361); pfam11841
ELMO/CED-12 family; pfam04727
Pleckstrin homology-like domain; cl00273
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
DC-STAMP-like protein; pfam07782
Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; COG0471
Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; cl15356
Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; COG0471
Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; cl15356
Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; COG0471
Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; cl15356
Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; cl15356
Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; cl15356
Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; COG0471
Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; COG0471
Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; cd01115
Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; cl15356
Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; COG0471
Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; COG0471
Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; cl15356
Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; cl15356
Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; cl15356
Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; COG0471
Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; COG0471
Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; cl15356
Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; cl15356
serine/threonine protein kinase; Provisional
Kae1-associated kinase Bud32; TIGR03724
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
eyes absent protein conserved domain; TIGR01658
eyes absent protein conserved domain; TIGR01658
eyes absent protein conserved domain; TIGR01658
PHD-finger; pfam00628
Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular...; cd05508
The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions.  BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND...; cd05841
Domain of unknown function (DUF3544); pfam12064
ATP synthase B/B' CF(0); cl07975
MYND finger; pfam01753
PHD-finger; pfam00628
Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular...; cd05508
The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions.  BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND...; cd05841
Domain of unknown function (DUF3544); pfam12064
ATP synthase B/B' CF(0); cl07975
MYND finger; pfam01753
PHD-finger; pfam00628
Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular...; cd05508
The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions.  BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND...; cd05841
Domain of unknown function (DUF3544); pfam12064
ATP synthase B/B' CF(0); cl07975
MYND finger; pfam01753
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
Steroid receptor coactivator; pfam08832
Nuclear receptor coactivator; pfam08815
Domain of unknown function (DUF1518); pfam07469
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
Steroid receptor coactivator; pfam08832
Nuclear receptor coactivator; pfam08815
Domain of unknown function (DUF1518); pfam07469
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
Steroid receptor coactivator; pfam08832
Nuclear receptor coactivator; pfam08815
Domain of unknown function (DUF1518); pfam07469
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
Steroid receptor coactivator; pfam08832
Nuclear receptor coactivator; pfam08815
Domain of unknown function (DUF1518); pfam07469
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; pfam00884
Sulfatase protein; pfam12548
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; pfam00884
Sulfatase protein; pfam12548
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; pfam00884
Sulfatase protein; pfam12548
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
DEP domain, named after Dishevelled, Egl-10, and Pleckstrin, where this domain was first discovered. The function of this domain is still not clear, but it is believed to be important for the membrane association of the signaling proteins in which it is...; cl02442
DEP (Dishevelled, Egl-10, and Pleckstrin) domain 2 found in P-Rex-like proteins. The P-Rex family is the guanine-nucleotide exchange factor (GEF) for the small GTPase Rac that contains an N-terminal RhoGEF domain, two DEP and PDZ domains. Rac-GEF...; cd04440
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; cd00136
SEC7 domain proteins [General function prediction only]
CRM1 C terminal; cl07396
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor...; cd00171
Domain of unknown function (DUF1981); pfam09324
Importin-beta N-terminal domain; smart00913
Cse1; pfam08506
CAS/CSE protein, C-terminus; pfam03378
Importin-beta N-terminal domain; smart00913
Cse1; pfam08506
CAS/CSE protein, C-terminus; pfam03378
Double-stranded RNA binding motif; smart00358
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif; smart00358
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif; smart00358
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif; smart00358
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
helicase 45; Provisional
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]
AAA domain; pfam13087
Presumably a zinc binding domain, which has been shown to bind to DNA in the human nuclear transcriptional repressor NF-X1. The zinc finger can be characterized by the pattern C-X(1-6)-H-X-C-X3-C(H/C)-X(3-4)-(H/C)-X(1-10)-C. The NF-X1 zinc finger...; cd06008
Presumably a zinc binding domain, which has been shown to bind to DNA in the human nuclear transcriptional repressor NF-X1. The zinc finger can be characterized by the pattern C-X(1-6)-H-X-C-X3-C(H/C)-X(3-4)-(H/C)-X(1-10)-C. The NF-X1 zinc finger...; cd06008
K+ channel tetramerisation domain; pfam02214
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion channel; pfam07885
Kv2 voltage-gated K+ channel; pfam03521
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; COG2124
Beta-4-Galactosyltransferase is involved in the formation of the poly-N-acetyllactosamine core structures present in glycoproteins and glycosphingolipids; cd00899
Sodium/hydrogen exchanger family; pfam00999
Sodium/hydrogen exchanger family; pfam00999
PHD-like zinc-binding domain; pfam13771
PHD-like zinc-binding domain; pfam13771
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Drought induced 19 protein (Di19); pfam05605
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Kua-ubiquitin conjugating enzyme hybrid localisation domain; pfam10520
Ubiquitin-conjugating enzyme E2, catalytic domain homologues; smart00212
Ubiquitin-conjugating enzyme E2, catalytic domain homologues; smart00212
Ubiquitin-conjugating enzyme E2, catalytic domain homologues; smart00212
Ubiquitin-conjugating enzyme E2, catalytic domain homologues; smart00212
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cl00154
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cl00154
Ubiquitin-conjugating enzyme E2, catalytic domain homologues; smart00212
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cl00154
Ubiquitin-conjugating enzyme E2, catalytic domain homologues; smart00212
Ubiquitin-conjugating enzyme E2, catalytic domain homologues; smart00212
Ubiquitin-conjugating enzyme E2, catalytic domain homologues; smart00212
Ubiquitin-conjugating enzyme E2, catalytic domain homologues; smart00212
Kua-ubiquitin conjugating enzyme hybrid localisation domain; pfam10520
Kua-ubiquitin conjugating enzyme hybrid localisation domain; pfam10520
Basic region leucine zipper; pfam07716
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
The PB1 domain is an essential part of Par6 protein which in complex with Par3 and aPKC proteins is crucial for establishment of apical-basal polarity of animal cells. The PB1 domain is a modular domain mediating specific protein-protein interactions...; cd06403
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
C2H2-type zinc-finger domain; pfam13909
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
C2H2-type zinc-finger domain; pfam13909
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
dolichyl-phosphate beta-D-mannosyltransferase
DPM1_like represents putative enzymes similar to eukaryotic DPM1; cd06442
hypothetical protein; Validated
ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; cd00757
Member of the Rhodanese Homology Domain superfamily. This CD includes several putative molybdopterin synthase sulfurylases including the molybdenum cofactor biosynthetic protein (CnxF) of Aspergillus nidulans and the molybdenum cofactor synthesis protein...; cd01526
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins; cd07881
IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction; cd01178
N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins; cd07881
IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction; cd01178
N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins; cd07881
IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction; cd01178
N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins; cd07881
IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction; cd01178
N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins; cd07881
IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction; cd01178
N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins; cd07881
IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction; cd01178
N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins; cd07881
IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction; cd01178
N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins; cd07881
IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction; cd01178
phospholipid-translocating P-type ATPase, flippase; TIGR01652
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid Dehalogenase-like Hydrolases; cl11391
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
C2H2-type zinc finger; pfam13912
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
C2H2-type zinc finger; pfam13912
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
C2H2-type zinc finger; pfam13912
C2H2-type zinc finger; pfam13912
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
C2H2-type zinc finger; pfam13912
C2H2-type zinc finger; pfam13912
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
C2H2-type zinc finger; pfam13912
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Prefoldin subunit; pfam01920
Pleckstrin homology (PH) domain; cd00821
IRS-like phosphotyrosine-binding domain; cd00824
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cl00147
7 transmembrane receptor (rhodopsin family); pfam00001
Protein of unknown function (DUF1279); pfam06916
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4; cd12000
Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module; cd11551
C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module; cd11568
Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4; cd12000
Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module; cd11551
C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module; cd11568
Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4; cd12000
C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module; cd11568
Src homology 3 domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4; cd12000
Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module; cd11551
C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein family member 4; a protein interaction module; cd11568
Replication termination factor 2; pfam04641
Core-2/I-Branching enzyme; pfam02485
Transcription factor AP-2; pfam03299
TGF-beta propeptide; pfam00688
Transforming growth factor-beta (TGF-beta) family; smart00204
SPO11 homologue; pfam03533
DNA topoisomerase VI subunit A; Provisional
Type IIB DNA topoisomerase; pfam04406
TOPRIM_TopoIIB_SPO: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in the type IIB family of DNA topoisomerases and Spo11. This subgroup contains proteins similar to Sulfolobus shibatae topoisomerase VI (TopoVI)...; cd00223
SPO11 homologue; pfam03533
Type IIB DNA topoisomerase; pfam04406
TOPRIM_TopoIIB_SPO: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in the type IIB family of DNA topoisomerases and Spo11. This subgroup contains proteins similar to Sulfolobus shibatae topoisomerase VI (TopoVI)...; cd00223
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; cd00819
Phosphoenolpyruvate carboxykinase; pfam00821
Adenosine deaminase z-alpha domain; cl02659
Adenosine deaminase z-alpha domain; cl02659
Adenosine deaminase z-alpha domain; cl02659
Adenosine deaminase z-alpha domain; cl02659
Adenosine deaminase z-alpha domain; cl02659
Adenosine deaminase z-alpha domain; cl02659
Adenosine deaminase z-alpha domain; cl02659
Rab-related GTPase family includes Rab5 and Rab22; regulates early endosome fusion; cd01860
Rab GTPase; Provisional
MSP (Major sperm protein) domain; pfam00635
MSP (Major sperm protein) domain; pfam00635
Syntaxin; pfam00804
Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in...; cd00193
Syntaxin; pfam00804
Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in...; cd00193
Syntaxin; pfam00804
Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in...; cd00193
Syntaxin; pfam00804
Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in...; cd00193
Syntaxin; pfam00804
Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in...; cd00193
Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; cd00433
Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; cd00433
Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; cd00433
Neuroendocrine-specific golgi protein P55 (NESP55); pfam06390
Neuroendocrine-specific golgi protein P55 (NESP55); pfam06390
G protein alpha subunit; smart00275
Alpha subunit of G proteins (guanine nucleotide binding); cd00066
G protein alpha subunit; smart00275
Alpha subunit of G proteins (guanine nucleotide binding); cd00066
G protein alpha subunit; smart00275
Alpha subunit of G proteins (guanine nucleotide binding); cd00066
G protein alpha subunit; smart00275
Alpha subunit of G proteins (guanine nucleotide binding); cd00066
G protein alpha subunit; smart00275
Alpha subunit of G proteins (guanine nucleotide binding); cd00066
TH1 protein; pfam04858
Cathepsin X; the only papain-like lysosomal cysteine peptidase exhibiting carboxymonopeptidase activity. It can also act as a carboxydipeptidase, like cathepsin B, but has been shown to preferentially cleave substrates through a monopeptidyl...; cd02698
tubulin beta chain; Provisional
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02187
Mitochondrial ATP synthase epsilon chain; pfam04627
PRELI-like family; pfam04707
PRELI-like family; pfam04707
Zinc-finger double domain; pfam13465
Endothelin family; pfam00322
Endothelin; smart00272
Endothelin family; pfam00322
Endothelin; smart00272
Endothelin family; pfam00322
Endothelin; smart00272
Endothelin family; pfam00322
Endothelin; smart00272
RPEL repeat; pfam02755
RPEL repeat; cl15286
RPEL repeat; pfam02755
RPEL repeat; cl15286
RPEL repeat; pfam02755
RPEL repeat; cl15286
RPEL repeat; pfam02755
RPEL repeat; cl15286
RPEL repeat; pfam02755
RPEL repeat; cl15286
Putative phosphatase regulatory subunit; pfam03370
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
alanine racemase; Reviewed; PRK03646
Cadherin prodomain like; pfam08758
Cadherin repeat-like domain; cl15786
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin cytoplasmic region; pfam01049
Cadherin prodomain like; pfam08758
Cadherin repeat-like domain; cl15786
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin cytoplasmic region; pfam01049
Cadherin prodomain like; cl07391
Cadherin repeat-like domain; cl15786
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin cytoplasmic region; pfam01049
NHR1 homology to TAF; pfam07531
TATA Binding Protein (TBP) Associated Factor 4 (TAF4) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex; cd08045
Like-Sm protein 14, N-terminal domain; cd01736
FDF domain; pfam09532
proteasome endopeptidase complex, archaeal, alpha subunit; TIGR03633
proteasome_alpha_type_7. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on...; cd03755
SSXT protein (N-terminal region); pfam05030
Obg family GTPase CgtA; TIGR02729
GTP1/OBG; pfam01018
Obg GTPase; cd01898
7 transmembrane receptor (rhodopsin family); pfam00001
Oxysterol-binding protein; pfam01237
Oxysterol-binding protein; pfam01237
Proteasome complex subunit Rpn13 ubiquitin receptor; pfam04683
Ubiquitin C-terminal hydrolase 37 receptor binding site; pfam13658
Proteasome complex subunit Rpn13 ubiquitin receptor; pfam04683
Ubiquitin C-terminal hydrolase 37 receptor binding site; pfam13658
Laminin N-terminal domain (domain VI); smart00136
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin B domain; smart00281
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin Domain I; pfam06008
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Laminin Domain II; pfam06009
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Ribosomal protein S21e; pfam01249
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Tumour-suppressor protein CtIP N-terminal domain; pfam10482
GATA-type transcription activator, N-terminal; pfam05349
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C; cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C; cd00202
Organic Anion Transporter Polypeptide (OATP) family; pfam03137
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a...; cd01330
7 transmembrane receptor (rhodopsin family); pfam00001
Chromatin modification-related protein EAF7; pfam07904
Opioid growth factor receptor (OGFr) conserved region; pfam04664
Uracil-DNA glycosylases (UDG) and related enzymes; cl00483
CSL zinc finger; pfam05207
Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]; COG5034
PHD-finger; pfam00628
Domain in the central regions of transcription elongation factor S-II (and elsewhere); smart00510
SPOC domain; pfam07744
Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]; COG5034
PHD-finger; pfam00628
Domain in the central regions of transcription elongation factor S-II (and elsewhere); smart00510
SPOC domain; pfam07744
Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]; COG5034
PHD-finger; pfam00628
Domain in the central regions of transcription elongation factor S-II (and elsewhere); smart00510
SPOC domain; pfam07744
Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]; COG5034
PHD-finger; pfam00628
Domain in the central regions of transcription elongation factor S-II (and elsewhere); smart00510
SPOC domain; pfam07744
Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]; COG5034
PHD-finger; pfam00628
Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]; COG5034
PHD-finger; pfam00628
LisH; pfam08513
CTLH/CRA C-terminal to LisH motif domain; pfam10607
C-terminal to LisH motif; smart00668
CT11-RanBPM; smart00757
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Major Facilitator Superfamily; pfam07690
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
YT521-B-like domain; pfam04146
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Na,K-Atpase Interacting protein; pfam05640
Putative GTPase activating protein for Arf; pfam01412
Putative GTPase activating protein for Arf; pfam01412
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
Collagen: The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions. The most abundant family is the collagens with more than 20 different...; cd01482
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cl00102
Collagen triple helix repeat (20 copies); pfam01391
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Ion transport protein; pfam00520
Ion channel; pfam07885
KCNQ voltage-gated potassium channel; pfam03520
Ankyrin-G binding motif of KCNQ2-3; pfam11956
Ion transport protein; pfam00520
Ion channel; pfam07885
KCNQ voltage-gated potassium channel; pfam03520
Ankyrin-G binding motif of KCNQ2-3; pfam11956
Ion transport protein; pfam00520
Ion channel; pfam07885
KCNQ voltage-gated potassium channel; pfam03520
Ankyrin-G binding motif of KCNQ2-3; pfam11956
Ion transport protein; pfam00520
Ion channel; pfam07885
KCNQ voltage-gated potassium channel; pfam03520
Ankyrin-G binding motif of KCNQ2-3; pfam11956
Ion transport protein; pfam00520
Ion channel; pfam07885
elongation factor 1- alpha; Provisional
Elongation Factor 1-alpha (EF1-alpha) protein family; cd01883
EF1_alpha_II: this family represents the domain II of elongation factor 1-alpha (EF-1a) that is found in archaea and all eukaryotic lineages. EF-1A is very abundant in the cytosol, where it is involved in the GTP-dependent binding of aminoacyl-tRNAs to...; cd03693
Domain III of EF-1. Eukaryotic elongation factor 1 (EF-1) is responsible for the GTP-dependent binding of aminoacyl-tRNAs to ribosomes. EF-1 is composed of four subunits: the alpha chain, which binds GTP and aminoacyl-tRNAs, the gamma chain that probably...; cd03705
Src homology 3 domain of Brk (Breast tumor kinase) Protein Tyrosine Kinase (PTK), also called PTK6; cd11847
Src homology 2 domain found in protein-tyrosine kinase-6 (PTK6) which is also known as breast tumor kinase (Brk); cd10358
Catalytic domain of the Protein Tyrosine Kinases, Srm and Brk; cd05148
Protein kinase; unclassified specificity; smart00221
Src homology 3 domain of Brk (Breast tumor kinase) Protein Tyrosine Kinase (PTK), also called PTK6; cd11847
Src homology 3 domain of Srms Protein Tyrosine Kinase; cd11846
Src homology 2 (SH2) domain found in Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristoylation sites (srm); cd10360
Catalytic domain of the Protein Tyrosine Kinases, Srm and Brk; cd05148
Protein tyrosine kinase; pfam07714
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]
AAA domain; pfam13087
This domain is the catalytic domain of ribonuclease II; smart00955
RNB domain; pfam00773
AAA domain; pfam13086
AAA domain; pfam13087
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]
AAA domain; pfam13087
This domain is the catalytic domain of ribonuclease II; smart00955
RNB domain; pfam00773
AAA domain; pfam13086
AAA domain; pfam13087
SAND domain; smart00258
Stathmin family; pfam00836
DEAD-like helicases superfamily; smart00488
DEAD_2; pfam06733
Helicase C-terminal domain; pfam13307
Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; COG1199
DEAD_2; pfam06733
Helicase C-terminal domain; pfam13307
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cl12111
GTPase SAR1 and related small G proteins [General function prediction only]
Arf-related protein 1 (Arfrp1); cd04160
GTPase SAR1 and related small G proteins [General function prediction only]
Arf-related protein 1 (Arfrp1); cd04160
GTPase SAR1 and related small G proteins [General function prediction only]
Arf-related protein 1 (Arfrp1); cd04160
Arf-related protein 1 (Arfrp1); cd04160
GTPase SAR1 and related small G proteins [General function prediction only]
GTPase SAR1 and related small G proteins [General function prediction only]
Arf-related protein 1 (Arfrp1); cd04160
GTPase SAR1 and related small G proteins [General function prediction only]
Arf-related protein 1 (Arfrp1); cd04160
GTPase SAR1 and related small G proteins [General function prediction only]
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
GTPase SAR1 and related small G proteins [General function prediction only]
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
zinc finger; smart00356
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
glycine rich nucleic binding domain; smart00443
zinc finger; smart00356
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
glycine rich nucleic binding domain; smart00443
zinc finger; smart00356
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
glycine rich nucleic binding domain; smart00443
zinc finger; smart00356
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
glycine rich nucleic binding domain; smart00443
zinc finger; smart00356
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
glycine rich nucleic binding domain; smart00443
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
alpha/beta hydrolase fold; pfam00561
Tumour protein D52 family; pfam04201
Tumour protein D52 family; pfam04201
Tumour protein D52 family; pfam04201
Tumour protein D52 family; pfam04201
Tumour protein D52 family; pfam04201
Tumour protein D52 family; pfam04201
Tumour protein D52 family; pfam04201
Tumour protein D52 family; pfam04201
Tumour protein D52 family; pfam04201
Tumour protein D52 family; pfam04201
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
Uridine kinase [Nucleotide transport and metabolism]; COG0572
Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; cd02023
Phosphoribosyl transferase (PRT)-type I domain; cd06223
Uridine kinase [Nucleotide transport and metabolism]; COG0572
Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; cd02023
Phosphoribosyl transferase (PRT)-type I domain; cd06223
SAM domain of aveugle-like subfamily; cd09510
SAM domain (Sterile alpha motif); pfam07647
PRP1 splicing factor, N-terminal; pfam06424
HAT (Half-A-TPR) repeats; smart00386
HAT (Half-A-TPR) repeats; smart00386
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
Sox C-terminal transactivation domain; pfam12067
Sox C-terminal transactivation domain; pfam12067
N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme; cd00183
transcription elongation factor S-II; TIGR01385
Transcription factor S-II (TFIIS), central domain; pfam07500
Transcription factor S-II (TFIIS); pfam01096
transcription elongation factor S-II; TIGR01385
N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme; cd00183
Transcription factor S-II (TFIIS), central domain; pfam07500
Transcription factor S-II (TFIIS); pfam01096
Regulator of G protein signaling (RGS) domain found in the RZ protein; cd08718
Regulator of G protein signaling (RGS) domain found in the RZ protein; cd08718
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
Zinc finger, C2HC type; pfam01530
Zinc finger, C2HC type; pfam01530
Zinc finger, C2HC type; pfam01530
Myelin transcription factor 1; pfam08474
Zinc finger, C2HC type; pfam01530
Zinc finger, C2HC type; pfam01530
Zinc finger, C2HC type; pfam01530
Zinc finger, C2HC type; pfam01530
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); pfam01135
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cl00053
C2 domain of PTEN tumour-suppressor protein; pfam10409
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cl00053
C2 domain of PTEN tumour-suppressor protein; pfam10409
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cl00053
C2 domain of PTEN tumour-suppressor protein; pfam10409
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Lipase; pfam00151
Pancreatic lipase-like enzymes.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is 'interfacial activation,' the...; cd00707
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Nucleotide-binding domain of human HSPA13 and similar proteins; cd10237
rod shape-determining protein MreB; Provisional
Lymphocyte signaling adaptor protein; pfam12485
Src homology 3 domain of SAM And SH3 Domain Containing Proteins; cd11822
SAM domain (Sterile alpha motif); pfam07647
SAM domain of SAMSN1 subfamily; cd09561
Lymphocyte signaling adaptor protein; pfam12485
Src homology 3 domain of SAM And SH3 Domain Containing Proteins; cd11822
SAM domain (Sterile alpha motif); pfam07647
SAM domain of SAMSN1 subfamily; cd09561
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02665
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02665
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
BTG family; pfam07742
tob/btg1 family; smart00099
EURL protein; pfam06937
EURL protein; pfam06937
EURL protein; pfam06937
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
Domain found in sea urchin sperm protein, enterokinase, agrin; smart00200
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Scavenger receptor Cys-rich; smart00202
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
First immunoglobulin (Ig)-like domain of neural cell adhesion molecule NCAM-2; cd05866
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Fifth immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-2 (also known as OCAM/mamFas II and RNCAM); cd05870
Immunoglobulin domain; cd00096
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; cd01667
TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; cd01667
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cd00096
Mitochondrial ATP synthase coupling factor 6; pfam05511
Mitochondrial ATP synthase coupling factor 6; pfam05511
Mitochondrial ATP synthase coupling factor 6; pfam05511
Mitochondrial ATP synthase coupling factor 6; pfam05511
Mitochondrial ATP synthase coupling factor 6; pfam05511
GA-binding protein alpha chain; pfam11620
Sterile alpha motif (SAM)/Pointed domain of GA-binding protein (GABP) alpha chain; cd08534
Ets-domain; pfam00178
GA-binding protein alpha chain; pfam11620
Sterile alpha motif (SAM)/Pointed domain of GA-binding protein (GABP) alpha chain; cd08534
Ets-domain; pfam00178
Amyloid A4 N-terminal heparin-binding; pfam02177
Copper-binding of amyloid precursor, CuBD; pfam12924
E2 domain of amyloid precursor protein; pfam12925
Beta-amyloid peptide (beta-APP); pfam03494
beta-amyloid precursor protein C-terminus; pfam10515
Amyloid A4 N-terminal heparin-binding; pfam02177
Copper-binding of amyloid precursor, CuBD; pfam12924
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
E2 domain of amyloid precursor protein; pfam12925
Beta-amyloid peptide (beta-APP); pfam03494
beta-amyloid precursor protein C-terminus; pfam10515
amyloid A4; smart00006
Amyloid A4 N-terminal heparin-binding; pfam02177
Copper-binding of amyloid precursor, CuBD; pfam12924
E2 domain of amyloid precursor protein; pfam12925
Beta-amyloid peptide (beta-APP); pfam03494
beta-amyloid precursor protein C-terminus; pfam10515
amyloid A4; smart00006
Amyloid A4 N-terminal heparin-binding; pfam02177
Copper-binding of amyloid precursor, CuBD; pfam12924
E2 domain of amyloid precursor protein; pfam12925
Beta-amyloid peptide (beta-APP); pfam03494
beta-amyloid precursor protein C-terminus; pfam10515
amyloid A4; smart00006
Amyloid A4 N-terminal heparin-binding; pfam02177
Copper-binding of amyloid precursor, CuBD; pfam12924
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
E2 domain of amyloid precursor protein; pfam12925
Plasmid replication region DNA-binding N-term; pfam11740
Beta-amyloid peptide (beta-APP); pfam03494
beta-amyloid precursor protein C-terminus; pfam10515
amyloid A4; smart00006
Amyloid A4 N-terminal heparin-binding; pfam02177
Copper-binding of amyloid precursor, CuBD; pfam12924
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
E2 domain of amyloid precursor protein; pfam12925
Plasmid replication region DNA-binding N-term; pfam11740
Beta-amyloid peptide (beta-APP); pfam03494
beta-amyloid precursor protein C-terminus; pfam10515
amyloid A4; smart00006
Amyloid A4 N-terminal heparin-binding; pfam02177
Copper-binding of amyloid precursor, CuBD; pfam12924
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
E2 domain of amyloid precursor protein; pfam12925
Plasmid replication region DNA-binding N-term; pfam11740
Beta-amyloid peptide (beta-APP); pfam03494
beta-amyloid precursor protein C-terminus; pfam10515
amyloid A4; smart00006
Amyloid A4 N-terminal heparin-binding; pfam02177
Copper-binding of amyloid precursor, CuBD; pfam12924
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
E2 domain of amyloid precursor protein; pfam12925
Plasmid replication region DNA-binding N-term; pfam11740
Beta-amyloid peptide (beta-APP); pfam03494
beta-amyloid precursor protein C-terminus; pfam10515
amyloid A4; smart00006
Amyloid A4 N-terminal heparin-binding; pfam02177
Copper-binding of amyloid precursor, CuBD; pfam12924
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
E2 domain of amyloid precursor protein; pfam12925
Plasmid replication region DNA-binding N-term; pfam11740
Beta-amyloid peptide (beta-APP); pfam03494
beta-amyloid precursor protein C-terminus; pfam10515
amyloid A4; smart00006
Amyloid A4 N-terminal heparin-binding; pfam02177
Copper-binding of amyloid precursor, CuBD; pfam12924
E2 domain of amyloid precursor protein; pfam12925
Beta-amyloid peptide (beta-APP); pfam03494
beta-amyloid precursor protein C-terminus; pfam10515
Protein of unknown function (DUF2668); pfam10873
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that...; cd04273
ADAM cysteine-rich; cl15456
Thrombospondin type 1 repeats; smart00209
ADAM-TS Spacer 1; pfam05986
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that...; cd04273
Thrombospondin type 1 repeats; smart00209
ADAM-TS Spacer 1; pfam05986
Thrombospondin type 1 repeats; smart00209
putative methyltransferase; Provisional
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
putative methyltransferase; Provisional
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
RWD domain; pfam05773
Protein of unknown function (DUF1115); pfam06544
Zn-finger in ubiquitin-hydrolases and other protein; pfam02148
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02667
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02667
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Zn-finger in ubiquitin-hydrolases and other protein; pfam02148
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02667
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02667
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Zn-finger in ubiquitin-hydrolases and other protein; pfam02148
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02667
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02667
Ubiquitin carboxyl-terminal hydrolase; pfam00443
TCP-1 (CTT or eukaryotic type II) chaperonin family, theta subunit. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings. In contrast to bacterial group I chaperonins; cd03341
TCP-1/cpn60 chaperonin family; pfam00118
SH3 domain protein; TIGR04211
BTB/POZ domain; pfam00651
basic region leucin zipper; smart00338
BTB/POZ domain; pfam00651
basic region leucin zipper; smart00338
Type 1 periplasmic binding fold superfamily; cl10011
Receptor family ligand binding region; pfam01094
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Ligand-gated ion channel; pfam00060
Eukaryotic homologues of bacterial periplasmic substrate binding proteins; smart00079
Type 1 periplasmic binding fold superfamily; cl10011
Receptor family ligand binding region; pfam01094
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Ligand-gated ion channel; pfam00060
Eukaryotic homologues of bacterial periplasmic substrate binding proteins; smart00079
PMP-22/EMP/MP20/Claudin family; cl15797
PMP-22/EMP/MP20/Claudin family; cl15797
PMG protein; pfam05287
PMG protein; pfam05287
PMG protein; pfam05287
PMG protein; pfam05287
PMG protein; pfam05287
PMG protein; pfam05287
PMG protein; pfam05287
PMG protein; pfam05287
PMG protein; pfam05287
PMG protein; pfam05287
Pleckstrin homology (PH) domain; cd00821
Ubiquitin-like proteins; cl00155
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
TIAM Pleckstrin homology (PH) domain; cd01255
Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; cd00305
Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; COG2032
VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal...; cl02544
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
CID (CTD-Interacting Domain) domain family; CID is present in several RNA-processing factors such as Pcf11 and Nrd1. Pcf11 is a conserved and essential subunit of the yeast cleavage factor IA, which is required for polyadenylation-dependent 3'-RNA...; cd03562
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
CID (CTD-Interacting Domain) domain family; CID is present in several RNA-processing factors such as Pcf11 and Nrd1. Pcf11 is a conserved and essential subunit of the yeast cleavage factor IA, which is required for polyadenylation-dependent 3'-RNA...; cd03562
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Ribosome 60S biogenesis N-terminal; pfam11707
Galactose binding lectin domain; pfam02140
Galactose binding lectin domain; pfam02140
Protein of unknown function (DUF2870); pfam11069
Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
SacI homology domain; pfam02383
Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of synaptojanin 1; cd09098
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
SacI homology domain; pfam02383
Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of synaptojanin 1; cd09098
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
SacI homology domain; pfam02383
Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of synaptojanin 1; cd09098
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
SacI homology domain; pfam02383
Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of synaptojanin 1; cd09098
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
GC-rich sequence DNA-binding factor-like protein; pfam07842
GC-rich sequence DNA-binding factor-like protein; pfam07842
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Tissue factor; pfam01108
Interferon-alpha/beta receptor, fibronectin type III; pfam09294
Tissue factor; pfam01108
Interferon-alpha/beta receptor, fibronectin type III; pfam09294
Putative binding domain; pfam13900
Tissue factor; pfam01108
Interferon-alpha/beta receptor, fibronectin type III; pfam09294
Putative binding domain; pfam13900
Tissue factor; pfam01108
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Tissue factor; pfam01108
Interferon-alpha/beta receptor, fibronectin type III; pfam09294
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
Interferon-alpha/beta receptor, fibronectin type III; pfam09294
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Uncharacterized protein family (UPF0220); pfam05255
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
Domain of unknown function (DUF1992); pfam09350
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
Domain of unknown function (DUF1992); pfam09350
phosphoribosylamine--glycine ligase; TIGR00877
Phosphoribosylglycinamide synthetase, N domain; pfam02844
Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; pfam01071
Phosphoribosylglycinamide synthetase, C domain; pfam02843
phosphoribosylaminoimidazole synthetase; Provisional
PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; cd02196
phosphoribosylglycinamide formyltransferase; Reviewed; PRK05647
Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); cd08645
phosphoribosylamine--glycine ligase; TIGR00877
Phosphoribosylglycinamide synthetase, N domain; pfam02844
Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; pfam01071
Phosphoribosylglycinamide synthetase, C domain; pfam02843
phosphoribosylaminoimidazole synthetase; Provisional
PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; cd02196
phosphoribosylglycinamide formyltransferase; Reviewed; PRK05647
Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); cd08645
phosphoribosylamine--glycine ligase; TIGR00877
Phosphoribosylglycinamide synthetase, N domain; pfam02844
Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; pfam01071
Phosphoribosylglycinamide synthetase, C domain; pfam02843
phosphoribosylaminoimidazole synthetase; Provisional
PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; cd02196
phosphoribosylglycinamide formyltransferase; Reviewed; PRK05647
Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); cd08645
phosphoribosylamine--glycine ligase; TIGR00877
Phosphoribosylglycinamide synthetase, N domain; pfam02844
Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; pfam01071
Phosphoribosylglycinamide synthetase, C domain; pfam02843
Protein of unknown function (DUF3729); pfam12526
G-patch domain; pfam01585
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Protein of unknown function (DUF3729); pfam12526
NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; COG0604
enoyl reductase of polyketide synthase; cd05195
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
flagellar export protein FliJ; TIGR02473
Na+/H+ antiporter subunit; cl00583
First Src homology 3 domain (or SH3A) of Intersectin-1; cd11987
Second Src homology 3 domain (or SH3B) of Intersectin-1; cd11989
Third Src homology 3 domain (or SH3C) of Intersectin-1; cd11991
Fourth Src homology 3 domain (or SH3D) of Intersectin-1; cd11993
Fifth Src homology 3 domain (or SH3E) of Intersectin-1; cd11995
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology (PH) domain; cd00821
C2 domain present in Intersectin; cd08375
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
flagellar export protein FliJ; TIGR02473
Na+/H+ antiporter subunit; cl00583
Src Homology 3 domain superfamily; cl17036
Second Src homology 3 domain (or SH3B) of Intersectin-1; cd11989
Third Src homology 3 domain (or SH3C) of Intersectin-1; cd11991
Fourth Src homology 3 domain (or SH3D) of Intersectin-1; cd11993
Fifth Src homology 3 domain (or SH3E) of Intersectin-1; cd11995
F0F1 ATP synthase subunit delta; Validated
ATP synthase delta (OSCP) subunit; pfam00213
Ribosomal protein S6; cl00414
Na(+)/myo-inositol cotransporter SMIT and related proteins; solute-binding domain; cd11491
putative transporter; Provisional
Solute carrier families 5 and 6-like; solute binding domain; cl00456
Slow voltage-gated potassium channel; pfam02060
monocarboxylate transporter 1; TIGR00892
Slow voltage-gated potassium channel; pfam02060
Slow voltage-gated potassium channel; pfam02060
Slow voltage-gated potassium channel; pfam02060
Slow voltage-gated potassium channel; pfam02060
Slow voltage-gated potassium channel; pfam02060
Slow voltage-gated potassium channel; pfam02060
Slow voltage-gated potassium channel; pfam02060
Slow voltage-gated potassium channel; pfam02060
Calcipressin; pfam04847
Calcipressin; pfam04847
Calcipressin; pfam04847
GST_N family, Chloride Intracellular Channel (CLIC) subfamily; composed of CLIC1-5, p64, parchorin and similar proteins. They are auto-inserting, self-assembling intracellular anion channels involved in a wide variety of functions including regulated...; cd03061
intracellular chloride channel protein; TIGR00862
C-terminal, alpha helical domain of Chloride Intracellular Channel 6; cd10301
Runt domain; pfam00853
Runx inhibition domain; pfam08504
Runt domain; pfam00853
Runx inhibition domain; pfam08504
Runt domain; pfam00853
Rubisco LSMT substrate-binding; pfam09273
SET domain; cl02566
Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs; cd05324
3-hydroxybutyrate dehydrogenase; TIGR01963
Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs; cd05324
3-hydroxybutyrate dehydrogenase; TIGR01963
Dopey, N-terminal; pfam04118
Dopey, N-terminal; cl04407
Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; cd00075
CW-type Zinc Finger; pfam07496
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
PMP-22/EMP/MP20/Claudin family; cl15797
PMP-22/EMP/MP20/Claudin family; cl15797
PMP-22/EMP/MP20/Claudin family; cl15797
PMP-22/EMP/MP20/Claudin family; cl15797
PMP-22/EMP/MP20/Claudin family; cl15797
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Single-minded protein C-terminus; pfam06621
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Single-minded protein C-terminus; pfam06621
Type 1 glutamine amidotransferase (GATase1)-like domain; cl00020
Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; COG0340
Biotin/lipoate A/B protein ligase family; pfam03099
Biotin protein ligase C terminal domain; pfam02237
Type 1 glutamine amidotransferase (GATase1)-like domain; cl00020
Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; COG0340
Biotin/lipoate A/B protein ligase family; pfam03099
Biotin protein ligase C terminal domain; pfam02237
Type 1 glutamine amidotransferase (GATase1)-like domain; cl00020
Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; COG0340
Biotin/lipoate A/B protein ligase family; pfam03099
Biotin protein ligase C terminal domain; pfam02237
PIG-P; pfam08510
PIG-P; pfam08510
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
Vacuolar protein sorting-associated protein 26; pfam03643
Arrestin (or S-antigen), N-terminal domain; cl02844
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Inward rectifier potassium channel; pfam01007
Ion transport protein; pfam00520
Inward rectifier potassium channel; pfam01007
Inward rectifier potassium channel; pfam01007
Inward rectifier potassium channel; pfam01007
Sterile alpha motif (SAM)/Pointed domain of ERG transcription factor; cd08540
Sterile alpha motif (SAM)/Pointed domain of ERG transcription factor; cd08540
Ets-domain; pfam00178
Sterile alpha motif (SAM)/Pointed domain of ERG transcription factor; cd08540
Ets-domain; pfam00178
Sterile alpha motif (SAM)/Pointed domain of ERG transcription factor; cd08540
Ets-domain; pfam00178
Sterile alpha motif (SAM)/Pointed domain of ERG transcription factor; cd08540
Ets-domain; pfam00178
Sterile alpha motif (SAM)/Pointed domain of ERG transcription factor; cd08540
Ets-domain; pfam00178
Sterile alpha motif (SAM)/Pointed domain of ERG transcription factor; cd08540
Ets-domain; pfam00178
Sterile alpha motif (SAM)/Pointed domain of ETS-2; cd08543
Ets-domain; pfam00178
Sterile alpha motif (SAM)/Pointed domain of ETS-2; cd08543
Ets-domain; pfam00178
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional...; cd05529
Bromodomain; WDR9 repeat II_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional...; cd05496
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional...; cd05529
Bromodomain; WDR9 repeat II_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional...; cd05496
CHD5-like protein; pfam04420
CHD5-like protein; pfam04420
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; cl12013
Glutaredoxin (GRX) family, SH3BGR (SH3 domain binding glutamic acid-rich protein) subfamily; a recently-identified subfamily composed of SH3BGR and similar proteins possessing significant sequence similarity to GRX, but without a redox active CXXC motif; cd03030
Glutaredoxin (GRX) family, SH3BGR (SH3 domain binding glutamic acid-rich protein) subfamily; a recently-identified subfamily composed of SH3BGR and similar proteins possessing significant sequence similarity to GRX, but without a redox active CXXC motif; cd03030
Galactosyltransferase; pfam01762
Galactosyltransferase; pfam01762
Galactosyltransferase; pfam01762
Galactosyltransferase; pfam01762
Immunoglobulin like; smart00410
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Seventh immunoglobulin (Ig)-like domain of Down Syndrome Cell Adhesion molecule (DSCAM); cd05734
Immunoglobulin I-set domain; pfam07679
Eight immunoglobulin (Ig) domain of Down Syndrome Cell Adhesion molecule (DSCAM); cd05735
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin domain; cd00096
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Seventh immunoglobulin (Ig)-like domain of Down Syndrome Cell Adhesion molecule (DSCAM); cd05734
Immunoglobulin I-set domain; pfam07679
Eight immunoglobulin (Ig) domain of Down Syndrome Cell Adhesion molecule (DSCAM); cd05735
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin domain; cd00096
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Beta-secretase, aspartic-acid protease important in the pathogenesis of Alzheimer's disease; cd05473
Eukaryotic aspartyl protease; pfam00026
Cellular and retroviral pepsin-like aspartate proteases; cl11403
Eukaryotic aspartyl protease; pfam00026
Cellular and retroviral pepsin-like aspartate proteases; cl11403
Dynamin_like protein family includes dynamins and Mx proteins; cd08771
Dynamin family; pfam00350
Predicted GTPases (dynamin-related) [General function prediction only]
Dynamin central region; pfam01031
Dynamin GTPase effector domain; smart00302
Dynamin_like protein family includes dynamins and Mx proteins; cd08771
Dynamin family; pfam00350
Dynamin central region; pfam01031
Dynamin GTPase effector domain; smart00302
Dynamin_like protein family includes dynamins and Mx proteins; cd08771
Dynamin family; pfam00350
Dynamin central region; pfam01031
Dynamin GTPase effector domain; smart00302
Dynamin_like protein family includes dynamins and Mx proteins; cd08771
Dynamin family; pfam00350
Dynamin central region; pfam01031
Dynamin GTPase effector domain; smart00302
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Scavenger receptor Cys-rich; smart00202
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Scavenger receptor Cys-rich; smart00202
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Protein kinase domain; pfam00069
Catalytic domain of Protein Kinases; cd00180
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
hypothetical protein
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
hypothetical protein
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
C2 domain found in the Human chromosome 21 open reading frame 25 (C21orf25) protein; cd08678
C2 domain found in the Human chromosome 21 open reading frame 25 (C21orf25) protein; cd08678
BTB/POZ domain; pfam00651
BTB/POZ domain; pfam00651
BTB/POZ domain; pfam00651
EMI domain; pfam07546
whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of...; cd00199
Calcium-binding EGF-like domain; smart00179
SEA domain; pfam01390
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
SEA domain; pfam01390
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Zona pellucida-like domain; pfam00100
EMI domain; pfam07546
whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of...; cd00199
Calcium-binding EGF-like domain; smart00179
SEA domain; pfam01390
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
SEA domain; pfam01390
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Zona pellucida-like domain; pfam00100
EMI domain; pfam07546
whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of...; cd00199
Calcium-binding EGF-like domain; smart00179
SEA domain; pfam01390
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
SEA domain; pfam01390
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Zona pellucida-like domain; pfam00100
EMI domain; pfam07546
whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of...; cd00199
Calcium-binding EGF-like domain; smart00179
SEA domain; pfam01390
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
SEA domain; pfam01390
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Zona pellucida-like domain; pfam00100
The Eye Pigment Precursor Transporter (EPP) Family protein; TIGR00955
ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR).  DR is a well-described phenomenon occurring in fungi and shares several similarities with processes...; cd03213
ABC-2 type transporter; pfam01061
The Eye Pigment Precursor Transporter (EPP) Family protein; TIGR00955
ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR).  DR is a well-described phenomenon occurring in fungi and shares several similarities with processes...; cd03213
ABC-2 type transporter; pfam01061
The Eye Pigment Precursor Transporter (EPP) Family protein; TIGR00955
ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR).  DR is a well-described phenomenon occurring in fungi and shares several similarities with processes...; cd03213
ABC-2 type transporter; pfam01061
The Eye Pigment Precursor Transporter (EPP) Family protein; TIGR00955
ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR).  DR is a well-described phenomenon occurring in fungi and shares several similarities with processes...; cd03213
ABC-2 type transporter; pfam01061
The Eye Pigment Precursor Transporter (EPP) Family protein; TIGR00955
ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR).  DR is a well-described phenomenon occurring in fungi and shares several similarities with processes...; cd03213
ABC-2 type transporter; pfam01061
The Eye Pigment Precursor Transporter (EPP) Family protein; TIGR00955
ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR).  DR is a well-described phenomenon occurring in fungi and shares several similarities with processes...; cd03213
ABC-2 type transporter; pfam01061
P or trefoil or TFF domain; Trefoil factor family domain peptides are mucin-associated molecules, largely found in epithelia of gastrointestinal tissues. Function is not known but it was originally identified from mucosal tissues, where it may have a...; cd00111
P or trefoil or TFF domain; Trefoil factor family domain peptides are mucin-associated molecules, largely found in epithelia of gastrointestinal tissues. Function is not known but it was originally identified from mucosal tissues, where it may have a...; cd00111
P or trefoil or TFF domain; Trefoil factor family domain peptides are mucin-associated molecules, largely found in epithelia of gastrointestinal tissues. Function is not known but it was originally identified from mucosal tissues, where it may have a...; cd00111
P or trefoil or TFF domain; Trefoil factor family domain peptides are mucin-associated molecules, largely found in epithelia of gastrointestinal tissues. Function is not known but it was originally identified from mucosal tissues, where it may have a...; cd00111
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Scavenger receptor Cys-rich; smart00202
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Scavenger receptor Cys-rich; smart00202
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Scavenger receptor cysteine-rich domain; cl02509
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Scavenger receptor Cys-rich; smart00202
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Src homology 3 domain of Ubiquitin-associated and SH3 domain-containing protein A; cd11937
Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; cd07067
Src homology 3 domain of Ubiquitin-associated and SH3 domain-containing protein A; cd11937
Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; cd07067
Src homology 3 domain of Ubiquitin-associated and SH3 domain-containing protein A; cd11937
Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; cd07067
Histidine phosphatase superfamily (branch 1); pfam00300
Uncharacterized protein conserved in bacteria [Function unknown]
MORN repeat; cl14787
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases; smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases; smart00698
MORN repeat; cl14787
Sugar phosphate permease [Carbohydrate transport and metabolism]; COG2271
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cl00076
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
cystathionine beta-synthase; TIGR01137
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; cd01561
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the pyridoxal-phosphate (PALP) dependent enzyme domain upstream.   The vitamin B6 complex comprises pyridoxine, pyridoxal, and pyridoxamine, as well...; cd04608
cystathionine beta-synthase; TIGR01137
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; cd01561
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the pyridoxal-phosphate (PALP) dependent enzyme domain upstream.   The vitamin B6 complex comprises pyridoxine, pyridoxal, and pyridoxamine, as well...; cd04608
cystathionine beta-synthase; TIGR01137
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; cd01561
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the pyridoxal-phosphate (PALP) dependent enzyme domain upstream.   The vitamin B6 complex comprises pyridoxine, pyridoxal, and pyridoxamine, as well...; cd04608
Zinc finger C-x8-C-x5-C-x3-H type (and similar); pfam00642
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
zinc finger; smart00356
Zinc finger C-x8-C-x5-C-x3-H type (and similar); pfam00642
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
zinc finger; smart00356
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
zinc finger; smart00356
Alpha crystallin A chain, N terminal; pfam00525
Alpha-crystallin domain found in the small heat shock protein (sHsp) alphaA-crystallin (HspB4, 20kDa). sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers...; cd06497
Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; COG0071
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Nucleolar protein,Nop52; pfam05997
Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6 in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; cd01173
pyridoxamine kinase; Validated
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains; cd00042
Nucleolar protein,Nop52; pfam05997
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; cd07990
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; cd07990
Trafficking protein particle complex subunit 10, TRAPPC10; pfam12584
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Dip2/Utp12 Family; pfam04003
isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional
Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; cd03133
isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional
Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; cd03133
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
ADDz domain of DNA (cytosine-5) methyltransferases (C5-MTases) 3 like (Dnmt3l); cd11727
ADDz domain of DNA (cytosine-5) methyltransferases (C5-MTases) 3 like (Dnmt3l); cd11727
Sp100 domain; pfam03172
SAND domain; pfam01342
PHD-finger; pfam00628
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cl15348
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent...; cd00764
6-phosphofructokinase, eukaryotic type; TIGR02478
Leucine rich repeat; pfam13855
Leucine Rich repeats (2 copies); pfam12799
occurring C-terminal to leucine-rich repeats; smart00446
Leucine rich repeat; pfam13855
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine Rich repeats (2 copies); pfam12799
occurring C-terminal to leucine-rich repeats; smart00446
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
occurring C-terminal to leucine-rich repeats; smart00446
Ion transport protein; pfam00520
ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P.  Like other members of the Nudix hydrolase superfamily of enzymes, it is thought to require a divalent cation, such as Mg2+, for its activity. It also...; cd03670
Leucine rich repeat N-terminal domain; smart00013
Leucine rich repeat; pfam13855
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cl00102
EPTP domain; pfam03736
EPTP domain; pfam03736
EPTP domain; pfam03736
EPTP domain; pfam03736
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Small ubiquitin-related modifier (SUMO); cd01763
Ubiquitin homologues; smart00213
Integrin, beta chain; pfam00362
Integrin beta tail domain; pfam07965
Integrin beta cytoplasmic domain; pfam08725
Integrin, beta chain; pfam00362
Integrin beta tail domain; pfam07965
Integrin beta cytoplasmic domain; pfam08725
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase); smart00552
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase); smart00552
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase); smart00552
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase); smart00552
GDP-fucose protein O-fucosyltransferase 2; cd11298
GDP-fucose protein O-fucosyltransferase; pfam10250
GDP-fucose protein O-fucosyltransferase 2; cd11298
GDP-fucose protein O-fucosyltransferase; pfam10250
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cl00102
Collagen triple helix repeat (20 copies); pfam01391
Endostatin-like domain; the angiogenesis inhibitor endostatin is a C-terminal fragment of collagen XV/XVIII, a proteoglycan/collagen found in vessel walls and basement membranes; this domain has a compact globular fold similar to that of C-type lectins; cd00247
Domain of Unknown Function (DUF959); pfam06121
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cl00102
Collagen triple helix repeat (20 copies); pfam01391
Endostatin-like domain; the angiogenesis inhibitor endostatin is a C-terminal fragment of collagen XV/XVIII, a proteoglycan/collagen found in vessel walls and basement membranes; this domain has a compact globular fold similar to that of C-type lectins; cd00247
Reduced folate carrier; pfam01770
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
RFC reduced folate carrier; TIGR00806
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
RFC reduced folate carrier; TIGR00806
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
VWA_collagen alpha(VI) type: The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions. The most abundant family is the collagens with more than...; cd01480
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
VWA_collagen alpha(VI) type: The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions. The most abundant family is the collagens with more than...; cd01480
VWA_collagen alpha(VI) type: The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions. The most abundant family is the collagens with more than...; cd01480
VWA_collagen alpha(VI) type: The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions. The most abundant family is the collagens with more than...; cd01480
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
VWA_collagen alpha(VI) type: The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions. The most abundant family is the collagens with more than...; cd01480
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cd00198
VWA_collagen alpha(VI) type: The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions. The most abundant family is the collagens with more than...; cd01480
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
VWA_collagen alpha(VI) type: The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions. The most abundant family is the collagens with more than...; cd01480
VWA_collagen alpha(VI) type: The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions. The most abundant family is the collagens with more than...; cd01480
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
VWA_collagen alpha(VI) type: The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions. The most abundant family is the collagens with more than...; cd01480
glutamate formiminotransferase; TIGR02024
Formiminotransferase domain, N-terminal subdomain; pfam07837
Formiminotransferase domain; pfam02971
Formiminotransferase-cyclodeaminase; pfam04961
glutamate formiminotransferase; TIGR02024
Formiminotransferase domain, N-terminal subdomain; pfam07837
Formiminotransferase domain; pfam02971
Formiminotransferase-cyclodeaminase; pfam04961
squalene/oxidosqualene cyclases; TIGR01787
Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY)  and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization...; cd02892
squalene/oxidosqualene cyclases; TIGR01787
Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY)  and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization...; cd02892
squalene/oxidosqualene cyclases; TIGR01787
Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY)  and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization...; cd02892
squalene/oxidosqualene cyclases; TIGR01787
Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY)  and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization...; cd02892
Nuclear protein export factor [Intracellular trafficking and secretion / Cell division and chromosome partitioning]; COG5079
SAC3/GANP/Nin1/mts3/eIF-3 p25 family; pfam03399
metalloprotein, YbeY/Upfam0054 family
metalloprotein, YbeY/Upfam0054 family
Pericentrin-AKAP-450 domain of centrosomal targeting protein; pfam10495
DMAP1-binding Domain; pfam06464
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; COG0318
AMP-binding enzyme; pfam00501
AMP-binding enzyme; pfam00501
DMAP1-binding Domain; pfam06464
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; COG0318
AMP-binding enzyme; pfam00501
AMP-binding enzyme; pfam00501
DMAP1-binding Domain; pfam06464
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; COG0318
AMP-binding enzyme; pfam00501
AMP-binding enzyme; cl15778
DMAP1-binding Domain; pfam06464
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; COG0318
AMP-binding enzyme; pfam00501
DMAP1-binding Domain; pfam06464
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; COG0318
AMP-binding enzyme; pfam00501
DMAP1-binding Domain; pfam06464
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; COG0318
AMP-binding enzyme; pfam00501
DMAP1-binding Domain; pfam06464
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; COG0318
AMP-binding enzyme; pfam00501
S-100B: S-100B domain found in proteins similar to S100B. S100B is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy, to which...; cd05027
Src homology 3 domain of Protein arginine N-methyltransferase 2; cd11806
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Src homology 3 domain of Protein arginine N-methyltransferase 2; cd11806
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Src homology 3 domain of Protein arginine N-methyltransferase 2; cd11806
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Src homology 3 domain of Protein arginine N-methyltransferase 2; cd11806
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Src homology 3 domain of Protein arginine N-methyltransferase 2; cd11806
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
chaperonin_like superfamily. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. There are 2 main chaperonin groups. The symmetry of type I...; cl02777
TCP-1/cpn60 chaperonin family; pfam00118
XK-related protein; pfam09815
Pleckstrin homology-like domain; cl00273
SEFIR domain; pfam08357
HAD-superfamily class IIA hydrolase, TIGR01456, CECR5
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
HAD-superfamily class IIA hydrolase, TIGR01456, CECR5
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
Adenosine/AMP deaminase N-terminal; pfam08451
adenosine deaminase-related growth factor; TIGR01431
Adenosine deaminase-related growth factors (ADGF), a novel family of secreted growth-factors with sequence similarty to adenosine deaminase; cd01321
Adenosine deaminase-related growth factors (ADGF), a novel family of secreted growth-factors with sequence similarty to adenosine deaminase; cd01321
Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long...; cd05509
Mitochondrial carrier protein; pfam00153
mitochondrial carrier protein; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
ATP synthase (E/31 kDa) subunit; pfam01991
Archaeal/vacuolar-type H+-ATPase subunit E [Energy production and conversion]; COG1390
ATP synthase (E/31 kDa) subunit; pfam01991
Archaeal/vacuolar-type H+-ATPase subunit E [Energy production and conversion]; COG1390
ATP synthase (E/31 kDa) subunit; pfam01991
Archaeal/vacuolar-type H+-ATPase subunit E [Energy production and conversion]; COG1390
Apoptosis regulator proteins, Bcl-2 family; pfam00452
Apoptosis regulator proteins, Bcl-2 family; pfam00452
Apoptosis regulator proteins, Bcl-2 family; pfam00452
Apoptosis regulator proteins, Bcl-2 family; pfam00452
Apoptosis regulator proteins, Bcl-2 family; pfam00452
Apoptosis regulator proteins, Bcl-2 family; pfam00452
BH3 interacting domain (BID); pfam06393
BH3 interacting domain (BID); pfam06393
BH3 interacting domain (BID); pfam06393
BH3 interacting domain (BID); pfam06393
BH3 interacting domain (BID); pfam06393
BH3 interacting domain (BID); pfam06393
BH3 interacting domain (BID); pfam06393
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
The LIM domain of Mical (molecule interacting with CasL); cd09439
Protein of unknown function (DUF3585); pfam12130
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
The LIM domain of Mical (molecule interacting with CasL); cd09439
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
The LIM domain of Mical (molecule interacting with CasL); cd09439
Pex26 protein; pfam07163
Pex26 protein; pfam07163
Pex26 protein; pfam07163
tubulin alpha chain; Provisional
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02186
tubulin alpha chain; Provisional
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02186
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Ubiquitin carboxyl-terminal hydrolase; pfam00443
DiGeorge syndrome critical region 6 (DGCR6) protein; pfam07324
Proline dehydrogenase; cl03282
Proline dehydrogenase; pfam01619
Proline dehydrogenase; cl03282
Proline dehydrogenase; pfam01619
C-type lectin-like domain (CTLD) of the type found in DGCR2, an integral membrane protein deleted in DiGeorge Syndrome (DGS); cd03599
von Willebrand factor (vWF) type C domain; smart00214
C-type lectin-like domain (CTLD) of the type found in DGCR2, an integral membrane protein deleted in DiGeorge Syndrome (DGS); cd03599
von Willebrand factor (vWF) type C domain; smart00214
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
C-type lectin-like domain (CTLD) of the type found in DGCR2, an integral membrane protein deleted in DiGeorge Syndrome (DGS); cd03599
von Willebrand factor (vWF) type C domain; smart00214
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
C-type lectin-like domain (CTLD) of the type found in DGCR2, an integral membrane protein deleted in DiGeorge Syndrome (DGS); cd03599
von Willebrand factor (vWF) type C domain; smart00214
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Nuclear protein Es2; pfam09751
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Clathrin propeller repeat; pfam01394
Clathrin propeller repeat; pfam01394
Clathrin, heavy-chain linker; pfam09268
Clathrin-H-link; pfam13838
Clathrin heavy chain repeat homology; smart00299
Clathrin heavy chain repeat homology; smart00299
Clathrin heavy chain repeat homology; smart00299
Clathrin heavy chain repeat homology; smart00299
Region in Clathrin and VPS; pfam00637
Clathrin heavy chain repeat homology; smart00299
Clathrin heavy chain repeat homology; smart00299
Clathrin propeller repeat; pfam01394
Clathrin propeller repeat; pfam01394
Clathrin, heavy-chain linker; pfam09268
Clathrin-H-link; pfam13838
Clathrin heavy chain repeat homology; smart00299
Clathrin heavy chain repeat homology; smart00299
Clathrin heavy chain repeat homology; smart00299
Clathrin heavy chain repeat homology; smart00299
Region in Clathrin and VPS; pfam00637
Clathrin heavy chain repeat homology; smart00299
Region in Clathrin and VPS; pfam00637
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
HIRA B motif; pfam09453
TUP1-like enhancer of split; pfam07569
Mitochondrial ribosomal protein L28; pfam09812
Ubiquitin fusion-degradation protein [Posttranslational modification, protein turnover, chaperones]; COG5140
Ubiquitin fusion degradation protein UFD1; pfam03152
Ubiquitin fusion-degradation protein [Posttranslational modification, protein turnover, chaperones]; COG5140
Ubiquitin fusion degradation protein UFD1; pfam03152
CDC45-like protein; pfam02724
CDC45-like protein; pfam02724
CDC45-like protein; pfam02724
PMP-22/EMP/MP20/Claudin family; cl15797
PMP-22/EMP/MP20/Claudin family; cl15797
Septin; pfam00735
CDC/Septin GTPase family; cd01850
CDC/Septin GTPase family; cd01850
Leucine rich repeat C-terminal domain; smart00082
T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA...; cd00182
T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA...; cd00182
T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA...; cd00182
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
DNA polymerase III subunits gamma and tau; Validated
thioredoxin and glutathione reductase selenoprotein; TIGR01438
Carboxy-terminal domain of Formyltransferase and similar domains; cl14785
Pyridine nucleotide-disulphide oxidoreductase; pfam00070
Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; pfam02852
Predicted O-methyltransferase [General function prediction only]
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Predicted O-methyltransferase [General function prediction only]
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Predicted O-methyltransferase [General function prediction only]
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
NRDE protein; pfam05742
Domain with 2 conserved Trp (W) residues; smart00456
Double-stranded RNA binding motif; pfam00035
Double-stranded RNA binding motif; pfam00035
Domain with 2 conserved Trp (W) residues; smart00456
Double-stranded RNA binding motif; pfam00035
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; COG2265
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; COG2265
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; COG2265
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Ran-binding domain; cd00835
DHHC palmitoyltransferase; pfam01529
DHHC palmitoyltransferase; pfam01529
Domain of unknown function (DUF4391); pfam14335
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
DiGeorge syndrome critical region 6 (DGCR6) protein; pfam07324
First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins; cd12014
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
Src Homology 3 domain superfamily; cl17036
Src homology 3 domains of Rab3-interacting molecules (RIMs) binding proteins; cd11851
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; smart00875
Kelch motif; pfam01344
Kelch motif; pfam01344
Kelch motif; pfam01344
Kelch motif; pfam01344
Kelch motif; pfam01344
ARC105 or Med15 subunit of Mediator complex non-fungal; pfam09606
ARC105 or Med15 subunit of Mediator complex non-fungal; pfam09606
Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the...; cd00871
Phosphoinositide 4-kinase (PI4K), Type III, alpha isoform, catalytic domain; The PI4K catalytic domain family is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein...; cd05167
Phosphoinositide 3-kinase, catalytic domain; smart00146
Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the...; cd00871
Phosphoinositide 4-kinase (PI4K), Type III, alpha isoform, catalytic domain; The PI4K catalytic domain family is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein...; cd05167
Phosphoinositide 3-kinase, catalytic domain; smart00146
Heparin cofactor II (HCII) inhibits thrombin, the final protease of the coagulation cascade. HCII is allosterically activated by binding to cell surface glycosaminoglycans (GAGs). The specificity of HCII for thrombin is conferred by a highly acidic...; cd02047
Helical region found in SNAREs; smart00397
SNAP-25 family; pfam00835
Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in...; cd00193
Src homology 2 domain found in cancer-related signaling adaptor protein CRK; cd09926
N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins; cd11758
C-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins; cd11759
AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The...; cd03478
Pyridine nucleotide-disulphide oxidoreductase; pfam07992
NAD(P)-binding Rossmann-like domain; pfam13450
Pyridine nucleotide-disulphide oxidoreductase; pfam00070
AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The...; cd03478
Pyridine nucleotide-disulphide oxidoreductase; pfam07992
NAD(P)-binding Rossmann-like domain; pfam13450
Pyridine nucleotide-disulphide oxidoreductase; pfam00070
AIFL (apoptosis-inducing factor like) family, N-terminal Rieske domain; members of this family show similarity to human AIFL, containing an N-terminal Rieske domain and a C-terminal pyridine nucleotide-disulfide oxidoreductase domain (Pyr_redox). The...; cd03478
Pyridine nucleotide-disulphide oxidoreductase; pfam07992
NAD(P)-binding Rossmann-like domain; pfam13450
Pyridine nucleotide-disulphide oxidoreductase; pfam00070
Galactose oxidase, central domain; pfam13415
epithiospecifier protein
Kelch motif; pfam13854
Galactose oxidase, central domain; pfam13415
Kelch motif; pfam01344
Kelch motif; pfam01344
Kelch motif; pfam01344
BTB And C-terminal Kelch; cl06652
BTB/POZ domain; pfam00651
The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion; smart00980
The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion; smart00980
cation transporter protein; TIGR00863
cation transporter protein; TIGR00863
cationic amino acid transport permease; TIGR00906
Spore germination protein; cl15802
C-terminus of AA_permease; pfam13906
First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins; cd12014
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Src Homology 3 domain superfamily; cl17036
Src homology 3 domains of Rab3-interacting molecules (RIMs) binding proteins; cd11851
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins; cd12014
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Src Homology 3 domain superfamily; cl17036
Src homology 3 domains of Rab3-interacting molecules (RIMs) binding proteins; cd11851
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
uncharacterized YdjC-like family proteins from eukaryotes; cd10806
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Modified RING finger domain; smart00504
cyclophilin_RING: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a modified RING finger domain. This group includes the nuclear proteins, Human hCyP-60 and Caenorhabditis elegans MOG-6 which, compared to the archetypal...; cd01923
peptidyl-prolyl cis-trans isomerase B (rotamase B); Provisional
Modified RING finger domain; smart00504
cyclophilin_RING: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a modified RING finger domain. This group includes the nuclear proteins, Human hCyP-60 and Caenorhabditis elegans MOG-6 which, compared to the archetypal...; cd01923
peptidyl-prolyl cis-trans isomerase B (rotamase B); Provisional
Modified RING finger domain; smart00504
cyclophilin_RING: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a modified RING finger domain. This group includes the nuclear proteins, Human hCyP-60 and Caenorhabditis elegans MOG-6 which, compared to the archetypal...; cd01923
peptidyl-prolyl cis-trans isomerase B (rotamase B); Provisional
Yippee putative zinc-binding protein; pfam03226
Catalytic domain of Extracellular signal-Regulated Kinase 1 and 2-like Serine/Threonine Kinases; cd07849
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Extracellular signal-Regulated Kinase 1 and 2-like Serine/Threonine Kinases; cd07849
Serine/Threonine protein kinases, catalytic domain; smart00220
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; cd00143
Protein phosphatase 2C; pfam00481
DNA topoisomerase I; Validated
TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; cd03362
DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; cd00186
Immunoglobulin domain; cl11960
Immunoglobulin V-Type; smart00406
Domain of unknown function (DUF4195); pfam13836
CHY zinc finger; pfam05495
Domain of unknown function (DUF4195); pfam13836
Gamma-glutamyltransferase [Amino acid transport and metabolism]; cl08040
Immunoglobulin Constant domain; cd07699
Immunoglobulin Constant domain; cd07699
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
HEAT repeats; pfam13646
G protein alpha subunit; smart00275
Alpha subunit of G proteins (guanine nucleotide binding); cd00066
Rab family protein; Provisional
Rab GTPase families 34 (Rab34) and 36 (Rab36); cd04108
Bcr-Abl oncoprotein oligomerisation domain; pfam09036
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
BCR (breakpoint cluster region)-related pleckstrin homology (PH) domain; cd01228
Pleckstrin homology-like domain; cl00273
C2 domain in the Active BCR (Breakpoint cluster region) Related protein; cd08686
RhoGAP_Bcr: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Bcr (breakpoint cluster region protein)-like proteins. Bcr is a multidomain protein with a variety of enzymatic functions. It contains a RhoGAP and a Rho GEF domain; cd04387
GTPase-activator protein for Rho-like GTPases; smart00324
Bcr-Abl oncoprotein oligomerisation domain; pfam09036
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
BCR (breakpoint cluster region)-related pleckstrin homology (PH) domain; cd01228
Pleckstrin homology-like domain; cl00273
C2 domain; cl14603
RhoGAP_Bcr: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Bcr (breakpoint cluster region protein)-like proteins. Bcr is a multidomain protein with a variety of enzymatic functions. It contains a RhoGAP and a Rho GEF domain; cd04387
GTPase-activator protein for Rho-like GTPases; smart00324
Immunoglobulin Constant domain; cd07699
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Immunoglobulin domain; cl11960
Immunoglobulin V-Type; smart00406
cyclic peptide transporter; TIGR01194
CHCH domain; pfam06747
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate...; cd04278
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
SNF5 / SMARCB1 / INI1; pfam04855
SNF5 / SMARCB1 / INI1; pfam04855
Der1-like family; pfam04511
Der1-like family; pfam04511
Der1-like family; pfam04511
Sugar (and other) transporter; pfam00083
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Sugar (and other) transporter; pfam00083
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Sugar (and other) transporter; pfam00083
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Macrophage migration inhibitory factor (MIF); pfam01187
Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; COG0625
GST_N family, Class Theta subfamily; composed of eukaryotic class Theta GSTs and bacterial dichloromethane (DCM) dehalogenase. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with...; cd03050
C-terminal, alpha helical domain of Class Theta Glutathione S-transferases; cd03183
Macrophage migration inhibitory factor (MIF); pfam01187
Macrophage migration inhibitory factor (MIF); pfam01187
Macrophage migration inhibitory factor (MIF); pfam01187
Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; COG0625
GST_N family, Class Theta subfamily; composed of eukaryotic class Theta GSTs and bacterial dichloromethane (DCM) dehalogenase. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with...; cd03050
C-terminal, alpha helical domain of Class Theta Glutathione S-transferases; cd03183
Macrophage migration inhibitory factor (MIF); pfam01187
Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; COG0625
GST_N family, Class Theta subfamily; composed of eukaryotic class Theta GSTs and bacterial dichloromethane (DCM) dehalogenase. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with...; cd03050
C-terminal, alpha helical domain of Class Theta Glutathione S-transferases; cd03183
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
MEF2 binding; pfam09047
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
MEF2 binding; pfam09047
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
MEF2 binding; pfam09047
Somatomedin B domain; pfam01033
Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family; pfam10342
Adhesion-associated domain present in MUC4 and other proteins; smart00723
von Willebrand factor type D domain; cl02516
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Gamma-glutamyltransferase [Amino acid transport and metabolism]; cl08040
Gamma-glutamyltranspeptidase; pfam01019
Gamma-glutamyltransferase [Amino acid transport and metabolism]; cl08040
Gamma-glutamyltranspeptidase; pfam01019
Gamma-glutamyltransferase [Amino acid transport and metabolism]; cl08040
Gamma-glutamyltranspeptidase; pfam01019
Tymovirus 45/70Kd protein; pfam03251
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Tymovirus 45/70Kd protein; pfam03251
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Tymovirus 45/70Kd protein; pfam03251
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cl00030
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
7 transmembrane receptor (rhodopsin family); pfam00001
beta-ureidopropionase
mammalian-like beta-alanine synthase (beta-AS) and similar proteins (class 5 nitrilases); cd07587
Peptidase_C39 like family; pfam13529
Guanylylate cyclase; pfam09778
Sm protein D3; cd01721
Gamma-glutamyltransferase [Amino acid transport and metabolism]; COG0405
Gamma-glutamyltranspeptidase; pfam01019
Gamma-glutamyltransferase [Amino acid transport and metabolism]; COG0405
Gamma-glutamyltranspeptidase; pfam01019
Gamma-glutamyltransferase [Amino acid transport and metabolism]; COG0405
Gamma-glutamyltranspeptidase; pfam01019
Gamma-glutamyltransferase [Amino acid transport and metabolism]; COG0405
Gamma-glutamyltranspeptidase; pfam01019
PAZ domain,  Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the...; cd02845
Piwi_piwi-like_Euk: PIWI domain, Piwi-like subfamily found in eukaryotes. This domain is found in Piwi and closely related proteins, where it is believed to perform a crucial role in germline cells, via RNA silencing. RNA silencing refers to a group of...; cd04658
PAZ domain,  Piwi_like subfamily. In multi-cellular organisms, the Piwi protein appears to be essential for the maintenance of germline stem cells. In the Drosophila male germline, Piwi was shown to be involved in the silencing of retrotransposons in the...; cd02845
Piwi_piwi-like_Euk: PIWI domain, Piwi-like subfamily found in eukaryotes. This domain is found in Piwi and closely related proteins, where it is believed to perform a crucial role in germline cells, via RNA silencing. RNA silencing refers to a group of...; cd04658
RUN domain; pfam02759
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
RUN domain; pfam02759
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
RUN domain; pfam02759
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
RUN domain; pfam02759
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
PMP-22/EMP/MP20/Claudin family; cl15797
Beta/Gamma crystallin; pfam00030
Beta/gamma crystallins; smart00247
Beta/Gamma crystallin; pfam00030
Beta/gamma crystallins; smart00247
Low-density lipoprotein receptor repeat class B; cl10508
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; cl10508
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; cl10508
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; cl10508
Low-density lipoprotein-receptor YWTD domain; smart00135
Regulator of G protein signaling domain (RGS) found in G protein-coupled receptor kinase 2 (GRK2) and  G protein-coupled receptor kinase 3 (GRK3); cd08747
Protein kinase domain; pfam00069
Catalytic domain of the Protein Serine/Threonine Kinase, beta-adrenergic receptor kinase; cd05606
Extension to Ser/Thr-type protein kinases; smart00133
Pleckstrin homology-like domain; cl00273
Myosin. Large ATPases; smart00242
Myosin motor domain, type XVIII myosins. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins are actin-dependent molecular motors that play important roles in muscle contraction, cell motility, and...; cd01386
Myosin tail; pfam01576
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Cupin domain; cl09118
SRR1; cl06844
Tuftelin interacting protein N terminal; pfam12457
G-patch domain; pfam01585
GC-rich sequence DNA-binding factor-like protein; pfam07842
Tuftelin interacting protein N terminal; pfam12457
G-patch domain; pfam01585
GC-rich sequence DNA-binding factor-like protein; pfam07842
Sulfotransferase family; pfam13469
Sulfotransferase family; pfam13469
Beta/Gamma crystallin; pfam00030
Beta/gamma crystallins; smart00247
Beta/Gamma crystallin; pfam00030
Beta/gamma crystallins; smart00247
Lipid-binding SRPBCC domain of mammalian PITPNA, -B, and related proteins (Class I PITPs); cd08888
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
CHAT domain; pfam12770
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
Fe-S protein assembly co-chaperone HscB; TIGR00714
HSCB C-terminal oligomerisation domain; pfam07743
basic region leucin zipper; smart00338
basic region leucin zipper; smart00338
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and...; cd00108
WSC domain; pfam01822
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and...; cd00108
WSC domain; pfam01822
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
EMI domain; pfam07546
EMI domain; pfam07546
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zn-finger in Ran binding protein and others; pfam00641
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zn-finger in Ran binding protein and others; pfam00641
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zn-finger in Ran binding protein and others; pfam00641
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zn-finger in Ran binding protein and others; pfam00641
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Growth-Arrest-Specific Protein 2 Domain; pfam02187
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Growth-Arrest-Specific Protein 2 Domain; pfam02187
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Growth-Arrest-Specific Protein 2 Domain; pfam02187
GTPase SAR1 and related small G proteins [General function prediction only]
Ras-related protein on chromosome 22 (RRP22) family; cd04142
Adaptin N terminal region; pfam01602
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Adaptin C-terminal domain; smart00809
Beta2-adaptin appendage, C-terminal sub-domain; smart01020
Adaptin N terminal region; pfam01602
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Adaptin C-terminal domain; smart00809
Beta2-adaptin appendage, C-terminal sub-domain; smart01020
Adaptin N terminal region; pfam01602
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Adaptin C-terminal domain; smart00809
Beta2-adaptin appendage, C-terminal sub-domain; smart01020
Ring finger; smart00184
RFPL defining motif (RDM); pfam11002
SPRY-associated domain; pfam13765
Domain in SPla and the RYanodine Receptor; smart00449
Intermediate filament protein; pfam00038
Repeat of unknown function (DUF1388); pfam07142
Fms-interacting protein; pfam09766
Fms-interacting protein; pfam09766
Fms-interacting protein; pfam09766
Fms-interacting protein; pfam09766
NIPSNAP; pfam07978
NIPSNAP; pfam07978
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
Ezrin/radixin/moesin family; pfam00769
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
Ezrin/radixin/moesin family; pfam00769
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
Ezrin/radixin/moesin family; pfam00769
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
Ezrin/radixin/moesin family; pfam00769
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
Ezrin/radixin/moesin family; pfam00769
Band 4.1 homologues; smart00295
FERM central domain; pfam00373
FERM_C domain; cd00836
Ezrin/radixin/moesin family; pfam00769
Band 4.1 homologues; smart00295
FERM central domain; pfam00373
FERM_C domain; cd00836
Ezrin/radixin/moesin family; pfam00769
Band 4.1 homologues; smart00295
FERM central domain; pfam00373
FERM_C domain; cd00836
Ezrin/radixin/moesin family; pfam00769
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Zinc-finger double-stranded RNA-binding; cl09952
Zinc finger C-x8-C-x5-C-x3-H type (and similar); pfam00642
Zinc-finger double-stranded RNA-binding; cl09952
Zinc finger C-x8-C-x5-C-x3-H type (and similar); pfam00642
Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like; pfam05365
Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like; pfam05365
Domain that may be involved in binding ubiquitin-conjugating enzymes (UBCs); smart00546
Domain that may be involved in binding ubiquitin-conjugating enzymes (UBCs); smart00546
Protein tyrosine phosphatase, catalytic domain motif; smart00404
Protein present in Fab1, YOTB, Vac1, and EEA1; smart00064
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Myotubularin-related; pfam06602
Myotubularin Y_phosphatase-like; pfam13849
Protein present in Fab1, YOTB, Vac1, and EEA1; smart00064
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Myotubularin-related; pfam06602
Myotubularin Y_phosphatase-like; pfam13849
Protein present in Fab1, YOTB, Vac1, and EEA1; smart00064
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
HORMA domain; pfam02301
leukemia inhibitory factor; smart00080
LIF / OSM family; pfam01291
Family description; pfam13840
Family description; pfam13840
GTPase-activating protein [General function prediction only]
Rab-GTPase-TBC domain; pfam00566
GTPase-activating protein [General function prediction only]
Rab-GTPase-TBC domain; pfam00566
Suppressor-of-White-APricot splicing regulator; smart00648
Suppressor-of-White-APricot splicing regulator; smart00648
Ubiquitin-like domain of Mammalian splicing factor SF3a_120; cd01800
Ubiquitin homologues; smart00213
Suppressor-of-White-APricot splicing regulator; smart00648
Suppressor-of-White-APricot splicing regulator; smart00648
Ubiquitin-like domain of Mammalian splicing factor SF3a_120; cd01800
Ubiquitin homologues; smart00213
Cdc37 N terminal kinase binding; cl03951
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
CRAL/TRIO, N-terminal domain; smart01100
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
Golgi-dynamics membrane-trafficking; pfam13897
CRAL/TRIO, N-terminal domain; smart01100
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
Golgi-dynamics membrane-trafficking; pfam13897
CRAL/TRIO, N-terminal domain; smart01100
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
Mitochondrial 18 KDa protein (MTP18); pfam10558
Mitochondrial 18 KDa protein (MTP18); pfam10558
CRAL/TRIO, N-terminal domain; smart01100
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
CRAL/TRIO, N-terminal domain; smart01100
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
CRAL/TRIO, N-terminal domain; smart01100
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
Golgi-dynamics membrane-trafficking; pfam13897
CRAL/TRIO, N-terminal domain; smart01100
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
Galactose-3-O-sulfotransferase; pfam06990
Pescadillo N-terminus; pfam06732
Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; cd00027
Pescadillo N-terminus; pfam06732
Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; cd00027
Eukaryotic cobalamin-binding protein; pfam01122
Eukaryotic cobalamin-binding protein; pfam01122
EamA-like transporter family; cl01037
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
Oxysterol binding protein (OSBP) Pleckstrin homology (PH) domain; cd01246
Oxysterol-binding protein; pfam01237
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; pfam13589
CW-type Zinc Finger; pfam07496
Smoothelin cytoskeleton protein; pfam12510
Smoothelin cytoskeleton protein; pfam12510
Smoothelin cytoskeleton protein; pfam12510
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Smoothelin cytoskeleton protein; pfam12510
Smoothelin cytoskeleton protein; pfam12510
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Smoothelin cytoskeleton protein; pfam12510
smoothelin-A; visceral smooth muscle-specific form
Smoothelin cytoskeleton protein; pfam12510
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Smoothelin cytoskeleton protein; pfam12510
Smoothelin cytoskeleton protein; pfam12510
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Smoothelin cytoskeleton protein; pfam12510
Smoothelin cytoskeleton protein; pfam12510
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Sep15/SelM redox domain; pfam08806
Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of inositol polyphosphate 5-phosphatase J and related proteins; cd09094
PLA2_bee_venom_like: A sub-family of  Phospholipase A2, similar to bee venom PLA2. PLA2 is a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. Enzymatically active PLA2 cleaves the sn-2 position of the...; cd04704
PLA2_group_III_like: A sub-family of  Phospholipase A2, similar to human group III PLA2. PLA2 is a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. Enzymatically active PLA2 cleaves the sn-2 position...; cd04705
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cl15348
The first LIM domain of LIMK2 (LIM domain Kinase 2); cd09463
The second LIM domain of LIMK2 (LIM domain Kinase 2); cd09465
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Protein kinase; unclassified specificity; smart00221
Protein Kinases, catalytic domain; cl09925
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
The second LIM domain of LIMK2 (LIM domain Kinase 2); cd09465
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Protein kinase; unclassified specificity; smart00221
Protein Kinases, catalytic domain; cl09925
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
The second LIM domain of LIMK2 (LIM domain Kinase 2); cd09465
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Protein kinase; unclassified specificity; smart00221
Catalytic domain of Protein Kinases; cd00180
PKC-activated protein phosphatase-1 inhibitor; pfam05361
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and...; cd00108
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and...; cd00108
BTB/POZ domain; pfam00651
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
BTB/POZ domain; pfam00651
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
BTB/POZ domain; pfam00651
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
BTB/POZ domain; pfam00651
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Predicted GTPase [General function prediction only]; COG1163
Developmentally Regulated GTP-binding protein (DRG); cd01896
TGS_DRG_C:   DRG (developmentally regulated GTP-binding protein) represents a family of GTP-binding proteins that includes two members, DRG1 and DRG2. DRG1 and DRG2 have a C-terminal TGS domain (named after the ThrRS, GTPase, and SpoT proteins where it...; cd01666
Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E; pfam10477
Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E; pfam10477
Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E; pfam10477
Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E; pfam10477
Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E; pfam10477
Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E; pfam10477
Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E; pfam10477
Sfi1 spindle body protein; pfam08457
Sfi1 spindle body protein; pfam08457
Sfi1 spindle body protein; pfam08457
Sfi1 spindle body protein; pfam08457
Sfi1 spindle body protein; pfam08457
Phosphatidylserine decarboxylase; pfam02666
Protein of unknown function (DUF3608); pfam12257
DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in DEPDC5-like proteins. DEPDC5, in human also known as KIAA0645, is a DEP domain containing protein of unknown function; cd04449
Protein of unknown function (DUF3608); pfam12257
DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in DEPDC5-like proteins. DEPDC5, in human also known as KIAA0645, is a DEP domain containing protein of unknown function; cd04449
Protein of unknown function (DUF3608); pfam12257
DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in DEPDC5-like proteins. DEPDC5, in human also known as KIAA0645, is a DEP domain containing protein of unknown function; cd04449
Protein of unknown function (DUF3608); pfam12257
DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in DEPDC5-like proteins. DEPDC5, in human also known as KIAA0645, is a DEP domain containing protein of unknown function; cd04449
Protein of unknown function (DUF3608); pfam12257
14-3-3 eta, an isoform of 14-3-3 protein; cd10025
Na(+)/glucose cotransporter SGLT1;solute binding domain; cd11486
putative transporter; Provisional
Solute carrier families 5 and 6-like; solute binding domain; cl00456
Ring finger; smart00184
RFPL defining motif (RDM); pfam11002
SPRY-associated domain; pfam13765
Domain in SPla and the RYanodine Receptor; smart00449
Ring finger; smart00184
RFPL defining motif (RDM); pfam11002
SPRY-associated domain; pfam13765
Domain in SPla and the RYanodine Receptor; smart00449
Ring finger; smart00184
RFPL defining motif (RDM); pfam11002
SPRY-associated domain; pfam13765
Domain in SPla and the RYanodine Receptor; smart00449
Ring finger; smart00184
RFPL defining motif (RDM); pfam11002
SPRY-associated domain; pfam13765
Domain in SPla and the RYanodine Receptor; smart00449
Solute carrier families 5 and 6-like; solute binding domain; cl00456
putative transporter; Provisional
Ring finger; smart00184
RFPL defining motif (RDM); pfam11002
SPRY-associated domain; pfam13765
Domain in SPla and the RYanodine Receptor; smart00449
Ring finger; smart00184
RFPL defining motif (RDM); pfam11002
SPRY-associated domain; pfam13765
Domain in SPla and the RYanodine Receptor; smart00449
hypothetical protein; Reviewed
Uncharacterized protein family UPF0027; pfam01139
BPI/LBP/CETP N-terminal domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) N-terminal domain; binds to and neutralizes lipopolysaccharides from the outer...; cd00025
BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative...; cl00188
PI31 proteasome regulator N-terminal; pfam11566
F-box-like; pfam12937
PI31 proteasome regulator N-terminal; pfam11566
F-box-like; pfam12937
PI31 proteasome regulator N-terminal; pfam11566
F-box-like; pfam12937
Synapsin N-terminal; pfam10581
Synapsin, N-terminal domain; pfam02078
Synapsin, ATP binding domain; pfam02750
Synapsin N-terminal; pfam10581
Synapsin, N-terminal domain; pfam02078
Synapsin, ATP binding domain; pfam02750
Synapsin N-terminal; pfam10581
Synapsin, N-terminal domain; pfam02078
Synapsin, ATP binding domain; pfam02750
NTR domain, TIMP subfamily; TIMPs, or tissue inibitors of metalloproteases, are essential regulators of extracellular matrix turnover and remodeling. They form complexes with matrix metalloproteases (MMPs) and inactivate them irreversibly by...; cd03585
LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis; cd06431
Glycosyl transferase family 8; pfam01501
Glycosyl-transferase for dystroglycan; pfam13896
LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis; cd06431
Glycosyl transferase family 8; pfam01501
Glycosyl-transferase for dystroglycan; pfam13896
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Domain of unknown function (DUF4171); pfam13775
High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I...; cd00084
VHS domain family, Tom1 subfamily; The VHS domain is an essential part of Tom1 (Target of myb1 - retroviral oncogene) protein. The VHS domain has a superhelical structure similar to the structure of the ARM repeats and is present at the very N-termini of...; cd03565
GAT domain; pfam03127
VHS domain family, Tom1 subfamily; The VHS domain is an essential part of Tom1 (Target of myb1 - retroviral oncogene) protein. The VHS domain has a superhelical structure similar to the structure of the ARM repeats and is present at the very N-termini of...; cd03565
GAT domain; pfam03127
VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal...; cl02544
GAT domain; pfam03127
VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal...; cl02544
GAT domain; pfam03127
Heme oxygenase catalyzes the rate limiting step in the degradation of heme to bilirubin, it is essential for recycling of iron from heme. Heme is used as a substrate and cofactor for its own degradation to biliverdin, iron, and carbon monoxide. This...; cd00232
minichromosome maintenance proteins; smart00350
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
GTPase SAR1 and related small G proteins [General function prediction only]
Ras homolog enriched in striatum (Rhes) and activator of G-protein signaling 1 (Dexras1/AGS1); cd04143
Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; cd01040
Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; cd01040
Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; cd01040
Apolipoprotein L; pfam05461
Apolipoprotein L; pfam05461
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Calcitonin gene-related peptide regulator C terminal; pfam12414
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Calcitonin gene-related peptide regulator C terminal; pfam12414
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Calcitonin gene-related peptide regulator C terminal; pfam12414
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Calcitonin gene-related peptide regulator C terminal; pfam12414
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Calcitonin gene-related peptide regulator C terminal; pfam12414
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Calcitonin gene-related peptide regulator C terminal; pfam12414
Apolipoprotein L; pfam05461
Apolipoprotein L; pfam05461
Apolipoprotein L; pfam05461
Apolipoprotein L; pfam05461
Apolipoprotein L; pfam05461
Apolipoprotein L; pfam05461
Apolipoprotein L; pfam05461
Apolipoprotein L; pfam05461
Apolipoprotein L; pfam05461
Apolipoprotein L; pfam05461
Apolipoprotein L; pfam05461
Myosin N-terminal SH3-like domain; pfam02736
Myosin. Large ATPases; smart00242
Myosin motor domain, type II myosins. Myosin II mediates cortical contraction in cell motility, and is the motor in smooth and skeletal muscle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins...; cd01377
Myosin tail; pfam01576
Protein of unknown function (DUF2869); pfam11068
TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; cd02947
Pyridine nucleotide-disulphide oxidoreductase; pfam13738
NAD(P)-binding Rossmann-like domain; pfam13450
Pyridine nucleotide-disulphide oxidoreductase; pfam13738
NAD(P)-binding Rossmann-like domain; pfam13450
Eukaryotic translation initiation factor 3 subunit 7 (eIF-3); pfam05091
PMP-22/EMP/MP20/Claudin family; pfam00822
Rab GTPase-like family 4 (Rab-like4); cd04101
Rab GTPase-like family 4 (Rab-like4); cd04101
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cl08302
The phosphoinositide binding Phox Homology domain of the p40phox subunit of NADPH oxidase; cd06882
Src Homology 3 domain of the p40phox subunit of NADPH oxidase; cd11869
The PB1 domain is essential part of the p40 adaptor protein which plays an important role in activating phagocyte NADPH oxidase during phagocytosis. The PB1 domain is a modular domain mediating specific protein-protein interaction which play a role in...; cd06399
The phosphoinositide binding Phox Homology domain of the p40phox subunit of NADPH oxidase; cd06882
Src Homology 3 domain of the p40phox subunit of NADPH oxidase; cd11869
The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1...; cl02720
Fibronectin type 3 domain; smart00060
Interleukin-6 receptor alpha chain, binding; cl12153
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; COG2897
Thiosulfate sulfurtransferases (TST) contain 2 copies of the Rhodanese Homology Domain. Only the second repeat contains the catalytically active Cys residue. The role of the 1st repeat is uncertain, but believed to be involved in protein interaction; cd01445
Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; cd01449
Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; COG2897
Thiosulfate sulfurtransferases (TST) contain 2 copies of the Rhodanese Homology Domain. Only the second repeat contains the catalytically active Cys residue. The role of the 1st repeat is uncertain, but believed to be involved in protein interaction; cd01445
Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; cd01449
3-mercaptopyruvate sulfurtransferase
Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; cd01448
Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; cd01449
Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; COG2897
Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; cd01448
Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; cd01449
Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; COG2897
Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; cd01448
Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; cd01449
K+ channel tetramerisation domain; pfam02214
SEA domain; pfam01390
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Collagen triple helix repeat (20 copies); pfam01391
C1q domain; pfam00386
Collagen triple helix repeat (20 copies); pfam01391
C1q domain; pfam00386
7 transmembrane receptor (rhodopsin family); pfam00001
GTPase SAR1 and related small G proteins [General function prediction only]
Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)-like consists of Rac1, Rac2 and Rac3; cd01871
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor...; cd00171
Cytohesin Pleckstrin homology (PH) domain; cd01252
Leucine rich repeat; pfam13855
Fringe-like; pfam02434
Fringe-like; pfam02434
Caspase activation and recruitment domain of CARD10-like proteins; cd08807
Src Homology 3 domain superfamily; cl17036
P21-Rho-binding domain; pfam00786
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
VHS domain family, GGA subfamily; GGA (Golgi-localized, Gamma-ear-containing, Arf-binding) comprise a subfamily of ubiquitously expressed, monomeric, motif-binding cargo/clathrin adaptor proteins. The VHS domain has a superhelical structure similar to...; cd03567
GAT domain; pfam03127
Adaptin C-terminal domain; smart00809
VHS domain family, GGA subfamily; GGA (Golgi-localized, Gamma-ear-containing, Arf-binding) comprise a subfamily of ubiquitously expressed, monomeric, motif-binding cargo/clathrin adaptor proteins. The VHS domain has a superhelical structure similar to...; cd03567
GAT domain; pfam03127
Adaptin C-terminal domain; smart00809
VHS domain family, GGA subfamily; GGA (Golgi-localized, Gamma-ear-containing, Arf-binding) comprise a subfamily of ubiquitously expressed, monomeric, motif-binding cargo/clathrin adaptor proteins. The VHS domain has a superhelical structure similar to...; cd03567
GAT domain; pfam03127
Adaptin C-terminal domain; smart00809
VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal...; cl02544
VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal...; cl02544
GAT domain; pfam03127
Adaptin C-terminal domain; smart00809
BAR domain; smart00721
The Bin/Amphiphysin/Rvs (BAR) domain of SH3-domain Binding Protein 1; cd07620
RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when...; cl02570
GTPase-activator protein for Rho-like GTPases; smart00324
phosphoglycolate/pyridoxal phosphate phosphatase family; TIGR01452
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Nucleolar protein 12 (25kDa); pfam09805
AF-4 proto-oncoprotein; pfam05110
Pleckstrin homology (PH) domain; cd00821
Bluetongue virus non-structural protein NS2; pfam04514
Pleckstrin homology (PH) domain; cd00821
Bluetongue virus non-structural protein NS2; pfam04514
Pleckstrin homology (PH) domain; cd00821
Bluetongue virus non-structural protein NS2; pfam04514
linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated...; cd00073
7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; COG0156
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); cd06454
7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; COG0156
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); cd06454
7 transmembrane receptor (rhodopsin family); pfam00001
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
RNA polymerase I-associated factor PAF67; pfam10255
RNA polymerase I-associated factor PAF67; pfam10255
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
This domain belongs to the LIM domain family which are found on Mical (molecule interacting with CasL) like proteins; cd09444
Protein of unknown function (DUF3585); pfam12130
Uncharacterized protein family (UPF0193); pfam05250
Uncharacterized protein family (UPF0193); pfam05250
DNA-directed RNA polymerase; Provisional
Sox developmental protein N terminal; pfam12444
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Arfaptin-like domain; pfam06456
The Bin/Amphiphysin/Rvs (BAR) domain of Protein Interacting with C Kinase 1; cd07659
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Arfaptin-like domain; pfam06456
The Bin/Amphiphysin/Rvs (BAR) domain of Protein Interacting with C Kinase 1; cd07659
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Arfaptin-like domain; pfam06456
The Bin/Amphiphysin/Rvs (BAR) domain of Protein Interacting with C Kinase 1; cd07659
monocarboxylate transporter 1; TIGR00892
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Brain-specific Angiogenesis Inhibitor 1-Associated Protein 2-Like 2; cd07644
IRSp53/MIM homology domain; pfam08397
Src Homology 3 domain of Brain-specific Angiogenesis Inhibitor 1-Associated Protein 2-Like 2; cd11914
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Patatin-like phospholipase domain containing protein 9; cd07212
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Patatin-like phospholipase domain containing protein 9; cd07212
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Patatin-like phospholipase domain containing protein 9; cd07212
bZIP Maf transcription factor; pfam03131
bZIP Maf transcription factor; pfam03131
bZIP Maf transcription factor; pfam03131
bZIP Maf transcription factor; pfam03131
Organic solute transporter Ostalpha; pfam03619
Organic solute transporter Ostalpha; pfam03619
Organic solute transporter Ostalpha; pfam03619
putative serine/threonine kinase; Provisional
Catalytic domain of Protein Kinases; cd00180
putative serine/threonine kinase; Provisional
Catalytic domain of Protein Kinases; cd00180
Inward rectifier potassium channel; pfam01007
Inward rectifier potassium channel; pfam01007
ER lumen protein retaining receptor; pfam00810
ER lumen protein retaining receptor; pfam00810
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
DEAD-like helicases superfamily; smart00487
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
DEAD-like helicases superfamily; smart00487
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
meiotic recombinase Dmc1; TIGR02238
Rad51_DMC1_radA,B. This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal proteins radA and radB. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a...; cd01123
Chibby, a nuclear inhibitor of Wnt/beta-catenin mediated transcription, and similar proteins; cd07429
Chibby, a nuclear inhibitor of Wnt/beta-catenin mediated transcription, and similar proteins; cd07429
Josephin; pfam02099
GTPase [General function prediction only]; COG5258
GTP binding protein 1 (GTPBP1)-like family includes GTPBP2; cd04165
Domain II of the GP-1 family of GTPase. This group includes proteins similar to GTPBP1 and GTPBP2. GTPB1 is structurally, related to elongation factor 1 alpha, a key component of protein biosynthesis machinery. Immunohistochemical analyses on mouse...; cd03694
Domain III of the GP-1 family of GTPase. This group includes proteins similar to GTPBP1 and GTPBP2. GTPB1 is structurally, related to elongation factor 1 alpha, a key component of protein biosynthesis machinery. Immunohistochemical analyses on mouse...; cd03708
Sad1 / UNC-like C-terminal; pfam07738
Sad1 / UNC-like C-terminal; pfam07738
Sad1 / UNC-like C-terminal; pfam07738
Dynein light chain type 1; pfam01221
Pentraxins are plasma proteins characterized by their pentameric discoid assembly and their Ca2+ dependent ligand binding, such as Serum amyloid P component (SAP) and C-reactive Protein (CRP), which are cytokine-inducible acute-phase proteins implicated...; cd00152
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
APOBEC-like N-terminal domain; pfam08210
Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; cd01283
APOBEC-like C-terminal domain; pfam05240
APOBEC-like N-terminal domain; pfam08210
APOBEC-like C-terminal domain; pfam05240
Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; cd01283
APOBEC-like N-terminal domain; pfam08210
APOBEC-like C-terminal domain; pfam05240
APOBEC-like N-terminal domain; pfam08210
APOBEC-like C-terminal domain; pfam05240
Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; cd01283
APOBEC-like N-terminal domain; pfam08210
APOBEC-like C-terminal domain; pfam05240
APOBEC-like N-terminal domain; pfam08210
APOBEC-like C-terminal domain; pfam05240
Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; cd01283
APOBEC-like N-terminal domain; pfam08210
APOBEC-like C-terminal domain; pfam05240
Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; cd01283
APOBEC-like N-terminal domain; pfam08210
APOBEC-like C-terminal domain; pfam05240
Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; cd01283
APOBEC-like N-terminal domain; pfam08210
APOBEC-like C-terminal domain; pfam05240
Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; cd01283
APOBEC-like N-terminal domain; pfam08210
Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; cd01283
APOBEC-like N-terminal domain; pfam08210
APOBEC-like C-terminal domain; pfam05240
Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; cd01283
APOBEC-like N-terminal domain; pfam08210
APOBEC-like C-terminal domain; pfam05240
APOBEC-like N-terminal domain; pfam08210
Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; cd01283
APOBEC-like C-terminal domain; pfam05240
Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; cd01283
APOBEC-like C-terminal domain; pfam05240
Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; cd01283
APOBEC-like C-terminal domain; pfam05240
Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; cd01283
APOBEC-like C-terminal domain; pfam05240
Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; cd01283
APOBEC-like C-terminal domain; pfam05240
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Platelet-derived growth factor, N terminal region; pfam04692
Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family domain; PDGF is a potent activator for cells of mesenchymal origin; PDGF-A and PDGF-B form AA and BB homodimers and an AB heterodimer; VEGF is a potent mitogen in embryonic and...; cd00135
Platelet-derived growth factor, N terminal region; pfam04692
Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family domain; PDGF is a potent activator for cells of mesenchymal origin; PDGF-A and PDGF-B form AA and BB homodimers and an AB heterodimer; VEGF is a potent mitogen in embryonic and...; cd00135
Ribosomal protein L3; cl00324
60S ribosomal protein L3; Provisional
Membrane-associating domain; pfam01284
Membrane-associating domain; pfam01284
Membrane-associating domain; pfam01284
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; cd00143
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; cd00143
Protein phosphatase 2C; pfam00481
Glycosyltransferase family 17; pfam04724
Glycosyltransferase family 17; pfam04724
Mab-21 protein; pfam03281
bZIP transcription factor; pfam00170
bZIP transcription factor; pfam00170
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated...; cd03571
N-terminal Src homology 3 domain of GRB2-related adaptor protein 2; cd11947
Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins; cd09941
C-terminal Src homology 3 domain of GRB2-related adaptor protein 2; cd11950
Protein of unknown function (DUF1669); pfam07894
N-terminal phospholipase D-like domain of the uncharacterized protein, Family with sequence similarity 83F; cd09186
Argonaute hook; pfam10427
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Argonaute hook; pfam10427
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Argonaute hook; pfam10427
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
adenylosuccinate lyase; TIGR00928
Adenylsuccinate lyase (ASL)_subgroup 2; cd03302
Adenylsuccinate lyase (ASL)_subgroup 2; cd03302
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
Src Homology 3 domain of Small G protein Signaling Modulator 3; cd11813
RUN domain; pfam02759
RPEL repeat; pfam02755
RPEL repeat; pfam02755
SAP domain; pfam02037
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13432
Heat shock chaperonin-binding motif; smart00727
proline aminopeptidase P II; Provisional
Aminopeptidase P, N-terminal domain; smart01011
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; cd01087
Putative binding domain; pfam13900
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
Component of SCF ubiquitin ligase and anaphase-promoting complex [Posttranslational modification, protein turnover, chaperones / Cell division and chromosome partitioning]; COG5194
TAZ zinc finger; pfam02135
KIX domain; pfam02172
Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to...; cd05495
Domain of Unknown Function (DUF902); pfam06001
Histone acetylation protein; pfam08214
Zinc finger, ZZ type. Zinc finger present in CBP/p300 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. CREB-binding protein (CBP) is a large multidomain protein that...; cd02337
TAZ zinc finger; pfam02135
Creb binding; pfam09030
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Leucine rich repeat; pfam13855
Leucine rich repeat N-terminal domain; cl02423
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Leucine rich repeat; pfam13855
RanGAP1 C-terminal domain; pfam07834
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
TPR repeat; pfam13414
Zinc-finger double-stranded RNA-binding; pfam12171
Zinc finger C-x8-C-x5-C-x3-H type (and similar); pfam00642
Basic region leucine zipper; pfam07716
Basic region leucine zipper; pfam07716
BTG family; pfam07742
PHF5-like protein; pfam03660
aconitate hydratase, mitochondrial; TIGR01340
Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; cd01584
Mitochondrial aconitase A swivel domain. Aconitase (also known as aconitate hydratase and citrate hydro-lyase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes...; cd01578
DNA-directed RNA polymerase, subunit E' [Transcription]; COG1095
RNAP_III_Rpc25_N: Rpc25, N-terminal ribonucleoprotein (RNP) domain. Rpc25 is a subunit of eukaryotic RNA polymerase (RNAP) III and is homologous to Rpa43 of eukaryotic RNAP I, Rpb7 of eukaryotic RNAP II, and RpoE of archaeal RNAP. Rpc25 has two domains; cd04330
RNA polymerase III subunit Rpc25; pfam08292
DNA-directed RNA polymerase, subunit E' [Transcription]; COG1095
RNAP_III_Rpc25_N: Rpc25, N-terminal ribonucleoprotein (RNP) domain. Rpc25 is a subunit of eukaryotic RNA polymerase (RNAP) III and is homologous to Rpa43 of eukaryotic RNAP I, Rpb7 of eukaryotic RNAP II, and RpoE of archaeal RNAP. Rpc25 has two domains; cd04330
RNA polymerase III subunit Rpc25; pfam08292
DNA-directed RNA polymerase, subunit E' [Transcription]; COG1095
RNAP_III_Rpc25_N: Rpc25, N-terminal ribonucleoprotein (RNP) domain. Rpc25 is a subunit of eukaryotic RNA polymerase (RNAP) III and is homologous to Rpa43 of eukaryotic RNAP I, Rpb7 of eukaryotic RNAP II, and RpoE of archaeal RNAP. Rpc25 has two domains; cd04330
RNA polymerase III subunit Rpc25; pfam08292
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
HAD-superfamily hydrolase, subfamily IIB; TIGR01484
PPPDE putative peptidase domain; pfam05903
ATP-dependent DNA helicase II, 70 kDa subunit (ku70); TIGR00578
Ku70/Ku80 N-terminal domain. The Ku78 heterodimer (composed of Ku70 and Ku80) contributes to genomic integrity through its ability to bind DNA double-strand breaks (DSB) in a preferred orientation. DSB's are repaired by either homologues recombination or...; cd01458
Ku-core domain, Ku70 subfamily; Ku70 is a subunit of the Ku protein, which plays a key role in multiple nuclear processes such as DNA repair, chromosome maintenance, transcription regulation, and V(D)J recombination. The mechanism underlying the...; cd00788
SAP domain; pfam02037
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; pfam01248
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Wnt and FGF inhibitory regulator; pfam13908
BAFF-R, TALL-1 binding; pfam09256
Centromere protein M (CENP-M); pfam11111
Centromere protein M (CENP-M); pfam11111
Centromere protein M (CENP-M); pfam11111
CDC/Septin GTPase family; cd01850
Septin; pfam00735
CDC/Septin GTPase family; cd01850
Septin; pfam00735
WW-domain ligand protein; pfam10349
The enzymes of glycosyl hydrolase family 31 (GH31) occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase; cl11402
Pleckstrin homology (PH) domain; cd00821
Putative mitochondrial precursor protein; pfam10161
Complex 1 protein (LYR family); pfam05347
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
PHD-like zinc-binding domain; pfam13771
PHD zinc finger; smart00249
PHD-like zinc-binding domain; pfam13771
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Ribosomal RNA-processing protein 7 (RRP7); pfam12923
Alpha/beta hydrolase family; pfam12697
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
NADH-cytochrome B5 reductase; Provisional
Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a...; cd06183
NADH-cytochrome B5 reductase; Provisional
Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a...; cd06183
NADH-cytochrome B5 reductase; Provisional
Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a...; cd06183
NADH-cytochrome B5 reductase; Provisional
Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a...; cd06183
NADH-cytochrome B5 reductase; Provisional
Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a...; cd06183
Mitochondrial ATP synthase g subunit; pfam04718
Glycosyltransferase sugar-binding region containing DXD motif; pfam04488
Alpha 1,4-glycosyltransferase conserved region; pfam04572
Putative GTPase activating protein for Arf; pfam01412
Putative GTPase activating protein for Arf; pfam01412
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; cl12013
Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2; cd11998
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2); cd07679
Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2; cd11998
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 2 (PACSIN2); cd07679
Src homology 3 domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1) and PACSIN 2; cd11998
Tubulin-tyrosine ligase family; pfam03133
Theoretical model of a pro-apoptotic protein; pfam12201
Acyl transferase domain; cl08282
malonyl CoA-acyl carrier protein transacylase; TIGR00128
Acyl transferase domain; cl08282
TspO/MBR family; pfam03073
TspO/MBR family; pfam03073
TspO/MBR family; pfam03073
Tubulin-tyrosine ligase family; pfam03133
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Complement Clr-like EGF-like; pfam12662
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Calcium-binding EGF-like domain; smart00179
GCC2 and GCC3; pfam07699
GCC2 and GCC3; pfam07699
GCC2 and GCC3; pfam07699
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Calcineurin-like phosphoesterase; pfam00149
Homo sapiens 239FB and related proteins, metallophosphatase domain; cd07379
Homo sapiens 239FB and related proteins, metallophosphatase domain; cd07379
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13833
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Domain of unknown function (DUF1880); pfam08976
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13833
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Domain of unknown function (DUF1880); pfam08976
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Sulfotransferase family; cl14559
Sulfotransferase domain; pfam00685
Patatins and Phospholipases; cl11396
Patatins and Phospholipases; cl11396
Patatin-like phospholipase domain containing protein 5; cd07223
Patatin-like phospholipase domain containing protein 3; cd07221
Surface antigen; pfam01103
Calponin homology (CH) domain; pfam00307
Calponin homology (CH) domain; pfam00307
Calponin homology (CH) domain; pfam00307
Calponin homology (CH) domain; pfam00307
Calponin homology (CH) domain; pfam00307
Calponin homology (CH) domain; pfam00307
Calponin homology (CH) domain; pfam00307
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cl00030
Calponin homology (CH) domain; pfam00307
Calponin homology (CH) domain; pfam00307
Calponin homology (CH) domain; pfam00307
Calponin homology (CH) domain; pfam00307
Calponin homology (CH) domain; pfam00307
Calponin homology (CH) domain; pfam00307
HbrB-like; pfam08539
HbrB-like; pfam08539
HbrB-like; pfam08539
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
RhoGAP-p50rhoGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of p50RhoGAP-like proteins; p50RhoGAP, also known as RhoGAP-1, contains a C-terminal RhoGAP domain and an N-terminal Sec14 domain which binds phosphatidylinositol...; cd04404
GTPase-activator protein for Rho-like GTPases; smart00324
HbrB-like; pfam08539
HbrB-like; pfam08539
HbrB-like; pfam08539
HbrB-like; pfam08539
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
RhoGAP-p50rhoGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of p50RhoGAP-like proteins; p50RhoGAP, also known as RhoGAP-1, contains a C-terminal RhoGAP domain and an N-terminal Sec14 domain which binds phosphatidylinositol...; cd04404
GTPase-activator protein for Rho-like GTPases; smart00324
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
RhoGAP-p50rhoGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of p50RhoGAP-like proteins; p50RhoGAP, also known as RhoGAP-1, contains a C-terminal RhoGAP domain and an N-terminal Sec14 domain which binds phosphatidylinositol...; cd04404
GTPase-activator protein for Rho-like GTPases; smart00324
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when...; cl02570
GTPase-activator protein for Rho-like GTPases; smart00324
PHD-finger; pfam00628
PHD-finger; pfam00628
PHD-finger; pfam00628
NUP50 (Nucleoporin 50 kDa); pfam08911
Ran-binding domain; cd00835
Ran-binding domain; cd00835
Uncharacterized conserved protein (DUF2045); pfam09741
Uncharacterized conserved protein (DUF2045); pfam09741
Uroplakin IIIa; cd09970
Uroplakin IIIb, IIIa and II; cl06408
Uroplakin IIIb, IIIa and II; cl06408
SIR2-like domain; pfam13289
SIR2-like domain; pfam13289
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
Eukaryotic SMC1 proteins; SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains.  Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal...; cd03275
SMC proteins Flexible Hinge Domain; smart00968
Eukaryotic SMC1 proteins; SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains.  Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal...; cd03275
RIB43A; pfam05914
Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to...; cd00017
Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to...; cd00017
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF domain; pfam07645
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Complement Clr-like EGF-like; pfam12662
Complement Clr-like EGF-like; pfam12662
Complement Clr-like EGF-like; pfam12662
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF domain; pfam07645
Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to...; cd00017
Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to...; cl00032
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF domain; pfam07645
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Complement Clr-like EGF-like; pfam12662
Complement Clr-like EGF-like; pfam12662
Complement Clr-like EGF-like; pfam12662
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to...; cd00017
Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to...; cd00017
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF domain; pfam07645
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Complement Clr-like EGF-like; pfam12662
Complement Clr-like EGF-like; pfam12662
Complement Clr-like EGF-like; pfam12662
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF domain; pfam07645
Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to...; cd00017
Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to...; cl00032
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF domain; pfam07645
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Complement Clr-like EGF-like; pfam12662
Complement Clr-like EGF-like; pfam12662
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Spinocerebellar ataxia type 10 protein domain; pfam09759
Spinocerebellar ataxia type 10 protein domain; pfam09759
wnt family; pfam00110
found in Wnt-1; smart00097
DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers; cd06965
The ligand binding domain of peroxisome proliferator-activated receptors; cd06932
DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers; cd06965
The ligand binding domain of peroxisome proliferator-activated receptors; cd06932
Cysteine-rich domain; pfam10170
REJ domain; pfam02010
G-protein-coupled receptor proteolytic site domain; smart00303
PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological...; cd01752
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
StaR_like; a well-conserved protein found in bacteria, plants, and animals. A family member from Streptomyces toyocaensis, StaR is part of a gene cluster involved in the biosynthesis of glycopeptide antibiotics (GPAs), specifically A47934. It has been...; cd05804
tRNA methyl transferase; pfam03054
tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; cd01998
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Domain present in hormone receptors; smart00008
Domain of unknown function (DUF3497); pfam12003
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
GRAM domain; pfam02893
diacylglycerol kinase
Rab-GTPase-TBC domain; pfam00566
TAFA family; pfam12020
TAFA family; pfam12020
Enhancer of polycomb-like; pfam10513
PHD-finger; pfam13831
PHD-zinc-finger like domain; pfam13832
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cl15348
Bromodomain; brd1_like subfamily. BRD1 is a mammalian gene which encodes for a nuclear protein assumed to be a transcriptional regulator. BRD1 has been implicated with brain development and susceptibility to schizophrenia and bipolar affective disorder; cd05512
The PWWP domain is found in the BR140 family, which includes peregrin and BR140-like proteins 1 and 2.   BR140 is the only family to contain the PWWP domain at the C terminus, with PHD and bromo domains in the N-terminal region.  In myeloid leukemias; cd05839
BED zinc finger; pfam02892
BED zinc finger; pfam02892
BED zinc finger; pfam02892
BED zinc finger; pfam02892
hAT family dimerisation domain; pfam05699
Dolichyl-phosphate-mannose-protein mannosyltransferase; cl15769
TLR4 regulator and MIR-interacting MSAP; pfam11938
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors; cl00066
Furin-like repeats; smart00261
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
TLR4 regulator and MIR-interacting MSAP; pfam11938
Furin-like repeats; smart00261
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors; cl00066
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Protein kinase domain; pfam00069
Catalytic domain of Protein Kinases; cd00180
Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
AAA domain; pfam13087
Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
AAA domain; pfam13087
Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
AAA domain; pfam13087
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]
AAA domain; pfam13087
Innexin; cl03000
Innexin; cl03000
TraB family; cl12050
Uncharacterized conserved protein [Function unknown]; cl00428
Uncharacterized conserved protein [Function unknown]; cl00428
Spc97 / Spc98 family; pfam04130
Tumour suppressor, Mitostatin; pfam13868
Spc97 / Spc98 family; pfam04130
Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; COG0123
Arginase-like and histone-like hydrolases; cl17011
Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; COG0123
Histone deacetylase 10; cd11683
Catalytic domain of the Serine/Threonine Kinase, p38gamma Mitogen-Activated Protein Kinase; cd07880
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Serine/Threonine Kinase, p38 Mitogen-Activated Protein Kinase; cd07851
Serine/Threonine protein kinases, catalytic domain; smart00220
The Sema domain, a protein interacting module, of Plexin B2; cd11276
semaphorin domain; smart00630
Plexin repeat; pfam01437
Plexin repeat; pfam01437
First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present...; cd01180
Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present...; cd01179
IPT/TIG domain; pfam01833
Plexin cytoplasmic RasGAP domain; pfam08337
Docking domain of Afi1 for Arf3 in vesicle trafficking; pfam07792
DENN (AEX-3) domain; cl11519
DENN (AEX-3) domain; cl11519
SIT4 phosphatase-associated protein; pfam04499
SIT4 phosphatase-associated protein; pfam04499
SIT4 phosphatase-associated protein; pfam04499
SIT4 phosphatase-associated protein; pfam04499
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
DENN (AEX-3) domain; pfam02141
Domain always found downstream of DENN domain, found in a variety of signalling proteins; smart00801
Myotubularin protein; pfam12335
Myotubularin-related; pfam06602
Myotubularin Y_phosphatase-like; pfam13849
Pleckstrin homology-like domain; cl00273
Family of unknown function (DUF706); pfam05153
Lipase maturation factor; pfam06762
Lipase maturation factor; pfam06762
Protein of unknown function (DUF1032); pfam06278
Protein of unknown function (DUF1032); pfam06278
Protein of unknown function (DUF1032); pfam06278
Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]
SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; cd02968
Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]
SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; cd02968
Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]
SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; cd02968
Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]
SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; cd02968
Glycosyl transferase family, helical bundle domain; pfam02885
pyrimidine-nucleoside phosphorylase; TIGR02644
Glycosyl transferase family, a/b domain; pfam00591
Pyrimidine nucleoside phosphorylase C-terminal domain; smart00941
Glycosyl transferase family, helical bundle domain; pfam02885
pyrimidine-nucleoside phosphorylase; TIGR02644
Glycosyl transferase family, a/b domain; pfam00591
Pyrimidine nucleoside phosphorylase C-terminal domain; smart00941
Glycosyl transferase family, helical bundle domain; pfam02885
pyrimidine-nucleoside phosphorylase; TIGR02644
Glycosyl transferase family, a/b domain; pfam00591
Pyrimidine nucleoside phosphorylase C-terminal domain; smart00941
Glycosyl transferase family, helical bundle domain; pfam02885
pyrimidine-nucleoside phosphorylase; TIGR02644
Glycosyl transferase family, a/b domain; pfam00591
Pyrimidine nucleoside phosphorylase C-terminal domain; smart00941
Glycosyl transferase family, helical bundle domain; pfam02885
pyrimidine-nucleoside phosphorylase; TIGR02644
Glycosyl transferase family, a/b domain; pfam00591
Pyrimidine nucleoside phosphorylase C-terminal domain; smart00941
Kelch motif; pfam01344
Kelch motif; pfam01344
Galactose oxidase, central domain; cl02701
Choline/Carnitine o-acyltransferase; pfam00755
Choline/Carnitine o-acyltransferase; pfam00755
Choline/Carnitine o-acyltransferase; pfam00755
Choline/Carnitine o-acyltransferase; pfam00755
Choline/Carnitine o-acyltransferase; pfam00755
Choline/Carnitine o-acyltransferase; pfam00755
Choline/Carnitine o-acyltransferase; pfam00755
Choline/Carnitine o-acyltransferase; pfam00755
choline kinase
Choline Kinase (ChoK) in eukaryotes. The ChoK subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK); cd05156
Src homology 3 domain of JNK-interacting protein 2; cd11942
JNK-interacting protein (JIP) Phosphotyrosine-binding (PTB) domain; cd01212
Src homology 3 domain of JNK-interacting protein 2; cd11942
JNK-interacting protein (JIP) Phosphotyrosine-binding (PTB) domain; cd01212
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; pfam00884
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; pfam00884
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; pfam00884
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; pfam00884
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; cl10460
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 3; cd11984
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
SAM domain of Shank1,2,3 family proteins; cd09506
SAM domain (Sterile alpha motif); pfam07647
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Rab GTPase-like family 2 (Rab-like2); cd04124
Rab GTPase-like family 2 (Rab-like2); cd04124
Rab GTPase-like family 2 (Rab-like2); cd04124
Rab GTPase-like family 2 (Rab-like2); cd04124
Rab GTPase-like family 2 (Rab-like2); cd04124
Rab GTPase-like family 2 (Rab-like2); cd04124
Rab GTPase-like family 2 (Rab-like2); cd04124
Catalytic domain of phosphatidylinositol-specific phospholipase C, X domain containing 1; cd08616
GTPases [General function prediction only]; COG2262
HflX GTPase family; cd01878
EF-hand domain pair; pfam13499
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Interleukin-6 receptor alpha chain, binding; pfam09240
Interleukin-6 receptor alpha chain, binding; pfam09240
Putative binding domain; pfam13900
Interleukin-6 receptor alpha chain, binding; pfam09240
Interleukin-6 receptor alpha chain, binding; pfam09240
Interleukin-6 receptor alpha chain, binding; pfam09240
Interleukin-6 receptor alpha chain, binding; pfam09240
Interleukin-6 receptor alpha chain, binding; pfam09240
Interleukin-6 receptor alpha chain, binding; pfam09240
Interleukin-6 receptor alpha chain, binding; pfam09240
Interleukin-6 receptor alpha chain, binding; pfam09240
Interleukin-6 receptor alpha chain, binding; pfam09240
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Maf-like protein; pfam02545
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; cd00555
C-20 methyltransferase BchU; TIGR02716
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Maf-like protein; pfam02545
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; cd00555
C-20 methyltransferase BchU; TIGR02716
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; cd00555
C-20 methyltransferase BchU; TIGR02716
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
7 transmembrane receptor (rhodopsin family); pfam00001
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
O-methyltransferase; pfam00891
short chain dehydrogenase; Provisional
retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs; cd05327
BED zinc finger; pfam02892
Domain of unknown function (DUF4413); pfam14372
hAT family dimerisation domain; pfam05699
BED zinc finger; pfam02892
Domain of unknown function (DUF4413); pfam14372
hAT family dimerisation domain; pfam05699
BED zinc finger; pfam02892
Domain of unknown function (DUF4413); pfam14372
hAT family dimerisation domain; pfam05699
CD99 antigen like protein 2; pfam12301
CD99 antigen like protein 2; pfam12301
CD99 antigen like protein 2; pfam12301
CD99 antigen like protein 2; pfam12301
CD99 antigen like protein 2; pfam12301
Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen; cd02537
Glycosyl transferase family 8; pfam01501
Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen; cd02537
Glycosyl transferase family 8; pfam01501
Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen; cd02537
Glycosyl transferase family 8; pfam01501
Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen; cd02537
Glycosyl transferase family 8; pfam01501
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; cl11394
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; cl10460
Sulfatase; cl10460
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; cl10460
Sulfatase; cl10460
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; cl10460
Sulfatase; cl10460
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; pfam00884
Sulfatase; cl10460
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; pfam00884
Sulfatase; cl10460
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; pfam00884
Sulfatase; cl10460
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Immunoglobulin like; smart00410
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin like; smart00410
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
protein kinase A catalytic subunit; Provisional
Catalytic domain of PRKX-like Protein Serine/Threonine Kinases; cd05612
Carboxylesterase family; pfam00135
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Carboxylesterase family; pfam00135
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
hydrolase
hydrolase
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
hydrolase
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
hydrolase
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; cl10460
Sulfatase; pfam00884
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Patatin-like phospholipase domain containing protein 4; cd07222
Patatin-like phospholipase domain containing protein 4; cd07222
Patatins and Phospholipases; cl11396
whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of...; cd00199
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
LisH; pfam08513
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Eukaryotic translation initiation factor eIF2A; pfam08662
LisH; pfam08513
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Eukaryotic translation initiation factor eIF2A; pfam08662
LisH; pfam08513
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Eukaryotic translation initiation factor eIF2A; pfam08662
LisH; pfam08513
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Eukaryotic translation initiation factor eIF2A; pfam08662
Ocular albinism type 1 protein; pfam02101
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Apx/Shroom domain ASD1; pfam08688
Apx/Shroom domain ASD2; pfam08687
C2 domain found in Human protein Kibra; cd08680
ClC-3-like chloride channel proteins.  This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has...; cd03684
Voltage gated chloride channel; pfam00654
FOG: CBS domain [General function prediction only]
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of...; cd04591
ClC-3-like chloride channel proteins.  This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has...; cd03684
Voltage gated chloride channel; pfam00654
FOG: CBS domain [General function prediction only]
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of...; cd04591
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
B-Box C-terminal domain; smart00502
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
SPRY-associated domain; pfam13765
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
SPRY-associated domain; pfam13765
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
SPRY-associated domain; pfam13765
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
SPRY-associated domain; pfam13765
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
SPRY-associated domain; pfam13765
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
B-Box C-terminal domain; smart00502
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Cytochrome c/c1 heme lyase; pfam01265
Cytochrome c/c1 heme lyase; pfam01265
Cytochrome c/c1 heme lyase; pfam01265
RhoGAP_ARHGAP6: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin...; cd04376
GTPase-activator protein for Rho-like GTPases; smart00324
RhoGAP_ARHGAP6: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin...; cd04376
GTPase-activator protein for Rho-like GTPases; smart00324
RhoGAP_ARHGAP6: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin...; cd04376
GTPase-activator protein for Rho-like GTPases; smart00324
Amelogenin; pfam02948
Amelogenin; pfam02948
Amelogenins, cell adhesion proteins, play a role in the biomineralisation of teeth; smart00818
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
MRG; pfam05712
MRG; pfam05712
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
MRG; pfam05712
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
MRG; pfam05712
MRG; pfam05712
MRG; pfam05712
MRG; pfam05712
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Band 4.1 homologues; smart00295
FERM central domain; pfam00373
ribose-phosphate pyrophosphokinase; Provisional
N-terminal domain of ribose phosphate pyrophosphokinase; pfam13793
Phosphoribosyl transferase (PRT)-type I domain; cd06223
ribose-phosphate pyrophosphokinase; Provisional
N-terminal domain of ribose phosphate pyrophosphokinase; pfam13793
Phosphoribosyl transferase (PRT)-type I domain; cd06223
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine Rich repeats (2 copies); pfam12799
TIR domain; cl15770
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
TIR domain; cl15770
Thymosin beta-4 family; pfam01290
Josephin; pfam02099
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
transcription elongation factor S-II; TIGR01385
N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme; cl00146
Transcription factor S-II (TFIIS), central domain; pfam07500
Rab GTPase family 9 (Rab9); cd04116
Rab GTPase family 9 (Rab9); cd04116
Sedlin, N-terminal conserved region; pfam04628
Sedlin, N-terminal conserved region; pfam04628
Sedlin, N-terminal conserved region; pfam04628
chromosome segregation protein; Provisional
Myelin proteolipid protein (PLP or lipophilin); pfam01275
Myelin proteolipid protein (PLP or lipophilin); pfam01275
Myelin proteolipid protein (PLP or lipophilin); pfam01275
Myelin proteolipid protein (PLP or lipophilin); pfam01275
Cation transporter family protein; TIGR00860
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Cation transporter family protein; TIGR00860
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Cation transporter family protein; TIGR00860
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
MSP (Major sperm protein) domain; pfam00635
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
MSP (Major sperm protein) domain; pfam00635
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
SOCS (suppressors of cytokine signaling) box of ASB9 and 11 proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system; cd03728
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
SOCS (suppressors of cytokine signaling) box of ASB9 and 11 proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system; cd03728
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
SOCS (suppressors of cytokine signaling) box of ASB9 and 11 proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system; cd03728
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
SOCS (suppressors of cytokine signaling) box of ASB9 and 11 proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system; cd03728
Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; cl10013
Glycosyltransferase [Cell envelope biogenesis, outer membrane]; COG0438
glycogen synthase, Corynebacterium family; TIGR02149
PIGA (GPI anchor biosynthesis); pfam08288
Glycosyl transferases group 1; pfam00534
Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family domain; PDGF is a potent activator for cells of mesenchymal origin; PDGF-A and PDGF-B form AA and BB homodimers and an AB heterodimer; VEGF is a potent mitogen in embryonic and...; cd00135
Pirin-related protein [General function prediction only]
Pirin; pfam02678
Pirin C-terminal cupin domain; pfam05726
Pirin-related protein [General function prediction only]
Pirin; pfam02678
Pirin C-terminal cupin domain; pfam05726
Tec pleckstrin homology (PH) domain; cd01238
Bruton's tyrosine kinase Cys-rich motif; smart00107
Src homology 2 (SH2) domain found  in Tec protein, Bmx; cd10399
Catalytic domain of the Protein Tyrosine Kinases, Bruton's tyrosine kinase and Bone marrow kinase on the X chromosome; cd05113
Protein tyrosine kinase; pfam07714
Tec pleckstrin homology (PH) domain; cd01238
Bruton's tyrosine kinase Cys-rich motif; smart00107
Src homology 2 (SH2) domain found  in Tec protein, Bmx; cd10399
Catalytic domain of the Protein Tyrosine Kinases, Bruton's tyrosine kinase and Bone marrow kinase on the X chromosome; cd05113
Protein tyrosine kinase; pfam07714
Angiotensin-converting enzyme; pfam01401
Peptidase family M2 Angiotensin converting enzyme (ACE); cd06461
Carbonic anhydrase alpha (vertebrate-like) group. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; cl00012
Zinc finger C-x8-C-x5-C-x3-H type (and similar); pfam00642
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zinc finger C-x8-C-x5-C-x3-H type (and similar); cl11592
Clathrin adaptor complex small chain; pfam01217
7 transmembrane receptor (rhodopsin family); pfam00001
CTP synthase
CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; cd03113
Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; cd01746
CTP synthase
CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; cd03113
Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; cd01746
CTP synthase
CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; cd03113
Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; cd01746
S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100...; cd00213
EF-hand domain pair; pfam13833
BSD domain; pfam03909
Myosin-like coiled-coil protein; pfam09728
Myosin-like coiled-coil protein; pfam09728
Histone-binding protein RBBP4 or subunit C of CAF1 complex; pfam12265
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Histone-binding protein RBBP4 or subunit C of CAF1 complex; pfam12265
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cl08302
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cl08302
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
SAM domain of Scm proteins of Polycomb group; cd09578
Sterile alpha motif; smart00454
SAM domain of Scm proteins of Polycomb group; cd09578
Sterile alpha motif; smart00454
SAM domain of Scm proteins of Polycomb group; cd09578
Sterile alpha motif; smart00454
SAM domain of Scm proteins of Polycomb group; cd09578
Sterile alpha motif; smart00454
Putative binding domain; pfam13900
The BEN domain is found in diverse animal proteins; smart01025
The BEN domain is found in diverse animal proteins; smart01025
Putative binding domain; pfam13900
The BEN domain is found in diverse animal proteins; smart01025
The BEN domain is found in diverse animal proteins; smart01025
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Protein of unknown function (DUF3588); pfam12140
SAM domain of Scm proteins of Polycomb group; cd09578
Sterile alpha motif; smart00454
Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase Like 5; cd07848
Protein kinase domain; pfam00069
Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase Like 5; cd07848
Protein kinase domain; pfam00069
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
IQ calmodulin-binding motif; cl15479
Drosophila melanogaster RdgC and related proteins, metallophosphatase domain; cd07420
Protein phosphatase 2A homologues, catalytic domain; smart00156
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
IQ calmodulin-binding motif; cl15479
Drosophila melanogaster RdgC and related proteins, metallophosphatase domain; cd07420
Protein phosphatase 2A homologues, catalytic domain; smart00156
metallophosphatase superfamily, metallophosphatase domain; cl13995
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
IQ calmodulin-binding motif; cl15479
Drosophila melanogaster RdgC and related proteins, metallophosphatase domain; cd07420
Protein phosphatase 2A homologues, catalytic domain; smart00156
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Glycosyl hydrolases family 15; pfam00723
Glycosyl hydrolases family 15; pfam00723
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
pyruvate dehydrogenase E1 component, alpha subunit; TIGR03182
Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; cd02000
pyruvate dehydrogenase E1 component, alpha subunit; TIGR03182
Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; cd02000
pyruvate dehydrogenase E1 component, alpha subunit; TIGR03182
Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; cd02000
pyruvate dehydrogenase E1 component, alpha subunit; TIGR03182
Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; cd02000
Domain of unknown function (DUF4071); pfam13281
Catalytic domain of the Protein Serine/Threonine Kinase, Apoptosis signal-regulating kinase; cd06624
Serine/Threonine protein kinases, catalytic domain; smart00220
First Src Homology 3 domain (SH3A) of Cbl-interacting protein of 85 kDa; cd12052
Second Src Homology 3 domain (SH3B) of Cbl-interacting protein of 85 kDa; cd12055
Third Src Homology 3 domain (SH3C) of Cbl-interacting protein of 85 kDa; cd12057
Second Src Homology 3 domain (SH3B) of Cbl-interacting protein of 85 kDa; cd12055
Third Src Homology 3 domain (SH3C) of Cbl-interacting protein of 85 kDa; cd12057
Third Src Homology 3 domain (SH3C) of Cbl-interacting protein of 85 kDa; cd12057
MAP7 (E-MAP-115) family; pfam05672
MAP7 (E-MAP-115) family; pfam05672
MAP7 (E-MAP-115) family; pfam05672
MAP7 (E-MAP-115) family; pfam05672
S1_IF1A: Translation initiation factor IF1A, also referred to as eIF1A in eukaryotes and aIF1A in archaea, S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. IF1A is essential for translation...; cd05793
Serine/Threonine protein kinases, catalytic domain; smart00220
N-terminal catalytic domain of the Protein Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase; cd05582
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
SAM domain of CNK1,2,3-suppressor subfamily; cd09511
Sterile alpha motif; smart00454
Connector enhancer of kinase suppressor of ras; pfam10534
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Protein of unknown function (DUF1170); pfam06663
Connector enhancer of KSR (Kinase suppressor of ras)  (CNK) pleckstrin homology (PH) domain; cd01260
SAM domain of CNK1,2,3-suppressor subfamily; cd09511
Sterile alpha motif; smart00454
Connector enhancer of kinase suppressor of ras; pfam10534
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Protein of unknown function (DUF1170); pfam06663
Connector enhancer of KSR (Kinase suppressor of ras)  (CNK) pleckstrin homology (PH) domain; cd01260
SAM domain of CNK1,2,3-suppressor subfamily; cd09511
Sterile alpha motif; smart00454
Connector enhancer of kinase suppressor of ras; pfam10534
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Protein of unknown function (DUF1170); pfam06663
Connector enhancer of KSR (Kinase suppressor of ras)  (CNK) pleckstrin homology (PH) domain; cd01260
SAM domain of CNK1,2,3-suppressor subfamily; cd09511
Sterile alpha motif; smart00454
Connector enhancer of kinase suppressor of ras; pfam10534
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Protein of unknown function (DUF1170); pfam06663
Connector enhancer of KSR (Kinase suppressor of ras)  (CNK) pleckstrin homology (PH) domain; cd01260
BTB/POZ domain; pfam00651
BTB And C-terminal Kelch; smart00875
Kelch motif; pfam01344
Sterol regulatory element-binding protein (SREBP) Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50A), regulates intramembrane proteolysis (RIP) of SREBP and is part of a signal transduction mechanism involved in sterol and lipid...; cd06162
PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; cd00987
Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; cl10020
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; COG3590
Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; cd08662
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
DEAD-like helicases superfamily; smart00487
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Patched family; pfam02460
Protein export membrane protein; cl14618
tryparedoxin peroxidase; Provisional
Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; cd03015
Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; cd03442
Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; cd03442
Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; cd03442
Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; cd03442
Acetyltransferases [General function prediction only]; COG0456
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; cd04301
Apolipoprotein O; pfam09769
Broad-Complex, Tramtrack and Bric a brac; smart00225
kelch-like protein; Provisional
BTB And C-terminal Kelch; smart00875
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch motif; pfam01344
eukaryotic translation initiation factor 2 gamma subunit; Provisional
Gamma subunit of initiation factor 2 (eIF2 gamma); cd01888
eIF2_gamma_II: this subfamily represents the domain II of the gamma subunit of eukaryotic translation initiation factor 2 (eIF2-gamma) found in Eukaryota and Archaea. eIF2 is a G protein that delivers the methionyl initiator tRNA to the small ribosomal...; cd03688
Initiation factor eIF2 gamma, C terminal; pfam09173
Zfx / Zfy transcription activation region; pfam04704
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zfx / Zfy transcription activation region; pfam04704
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zfx / Zfy transcription activation region; pfam04704
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zfx / Zfy transcription activation region; pfam04704
Zfx / Zfy transcription activation region; pfam04704
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Spt20 family; pfam12090
Spt20 family; pfam12090
Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase; pfam10436
Signal transduction histidine kinase [Signal transduction mechanisms]; COG0642
Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; cd00075
Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase; pfam10436
Signal transduction histidine kinase [Signal transduction mechanisms]; COG0642
Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; cd00075
CTP:phosphocholine cytidylyltransferase; cd02174
Cytidylyltransferase; pfam01467
CTP:phosphocholine cytidylyltransferase; cd02174
Cytidylyltransferase; pfam01467
CTP:phosphocholine cytidylyltransferase; cd02174
Cytidylyltransferase; pfam01467
DNA polymerase (pol2); TIGR00592
DNA polymerase alpha subunit p180 N terminal; pfam12254
inactive DEDDy 3'-5' exonuclease domain of eukaryotic DNA polymerase alpha, a family-B DNA polymerase; cd05776
DNA polymerase type-B alpha subfamily catalytic domain. Three DNA-dependent DNA polymerases type B (alpha, delta, and epsilon) have been identified as essential for nuclear DNA replication in eukaryotes. DNA polymerase (Pol) alpha is almost exclusively...; cd05532
DNA Polymerase alpha zinc finger; pfam08996
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
IL-beta-binding protein; Provisional
First immunoglobulin (Ig)-like domain of X-linked interleukin-1 receptor accessory protein-like 1 (IL1RAPL-1); cd05896
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
TIR domain; pfam01582
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Nuclear receptor repeat; pfam14046
Nuclear receptor repeat; pfam14046
Nuclear receptor repeat; pfam14046
Nuclear receptor repeat; pfam14046
The ligand binding domain of DAX1 protein, a nuclear receptor lacking DNA binding domain; cd07350
Metazoan glycerol kinase 1 and 3-like proteins; belongs to the FGGY family of carbohydrate kinases; cd07792
glycerol kinase; TIGR01311
Metazoan glycerol kinase 1 and 3-like proteins; belongs to the FGGY family of carbohydrate kinases; cd07792
glycerol kinase; TIGR01311
Metazoan glycerol kinase 1 and 3-like proteins; belongs to the FGGY family of carbohydrate kinases; cd07792
glycerol kinase; TIGR01311
Metazoan glycerol kinase 1 and 3-like proteins; belongs to the FGGY family of carbohydrate kinases; cd07792
glycerol kinase; TIGR01311
Domain that may be involved in binding ubiquitin-conjugating enzymes (UBCs); smart00546
Zinc finger domain; smart00547
eukaryotic ferritins; cd01056
Ferritin-like domain; pfam00210
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; cl02600
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; cl02600
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeat; pfam00435
Uncharacterized archaeal coiled-coil protein [Function unknown]
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeat; pfam00435
Uncharacterized archaeal coiled-coil protein [Function unknown]
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeat; pfam00435
Uncharacterized archaeal coiled-coil protein [Function unknown]
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeat; pfam00435
Uncharacterized archaeal coiled-coil protein [Function unknown]
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeat; pfam00435
Uncharacterized archaeal coiled-coil protein [Function unknown]
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Uncharacterized archaeal coiled-coil protein [Function unknown]
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeat; pfam00435
Uncharacterized archaeal coiled-coil protein [Function unknown]
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; cl02600
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; cl02600
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
large tegument protein UL36; Provisional
PMP-22/EMP/MP20/Claudin tight junction; pfam13903
104 kDa microneme/rhoptry antigen; Provisional
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
large tegument protein UL36; Provisional
Domain containing Gla (gamma-carboxyglutamate) residues; smart00069
Domain containing Gla (gamma-carboxyglutamate) residues; smart00069
Domain containing Gla (gamma-carboxyglutamate) residues; smart00069
Domain containing Gla (gamma-carboxyglutamate) residues; smart00069
Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain; cl02449
eukaryotic Lanthionine synthetase C-like protein. This family contains the lanthionine synthetase C-like proteins 1 and 2 which are related to the bacterial lanthionine synthetase components C (LanC). LANCL1 and LANCL2 (testes-specific adriamycin...; cd04794
Lanthionine synthetase C-like protein; pfam05147
eukaryotic Lanthionine synthetase C-like protein. This family contains the lanthionine synthetase C-like proteins 1 and 2 which are related to the bacterial lanthionine synthetase components C (LanC). LANCL1 and LANCL2 (testes-specific adriamycin...; cd04794
Lanthionine synthetase C-like protein; pfam05147
XK-related protein; pfam09815
Ferric reductase like transmembrane component; pfam01794
NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX...; cd06186
Tctex-1 family; pfam03645
C2 domain first repeat present in Synaptotagmin-like proteins 4 and 5; cd04029
C2 domain second repeat present in Synaptotagmin-like proteins 1-4; cd04020
C2 domain first repeat present in Synaptotagmin-like proteins 4 and 5; cd04029
C2 domain second repeat present in Synaptotagmin-like proteins 1-4; cd04020
C2 domain first repeat present in Synaptotagmin-like proteins 4 and 5; cd04029
C2 domain second repeat present in Synaptotagmin-like proteins 1-4; cd04020
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
HYR domain; pfam02494
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Domain of unknown function (DUF4174); pfam13778
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
HYR domain; pfam02494
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Domain of unknown function (DUF4174); pfam13778
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
HYR domain; pfam02494
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Domain of unknown function (DUF4174); pfam13778
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
HYR domain; pfam02494
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Domain of unknown function (DUF4174); pfam13778
Regulator of chromosome condensation (RCC1) repeat; pfam13540
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam13540
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam13540
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam13540
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
ornithine carbamoyltransferase; Provisional
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; pfam02729
Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; pfam00185
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), TM4SF2_6_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment...; cd03161
Thyroid hormone-inducible hepatic protein Spot 14; pfam07084
Thyroid hormone-inducible hepatic protein Spot 14; pfam07084
Thyroid hormone-inducible hepatic protein Spot 14; pfam07084
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Renin receptor-like protein; pfam07850
Uncharacterized protein family (UPF0041); pfam03650
Mediator complex subunit MED14; pfam08638
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02659
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02659
Ubiquitin carboxyl-terminal hydrolase; pfam00443
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
DEAD-like helicases superfamily; smart00487
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
DEAD-like helicases superfamily; smart00487
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
DEAD-like helicases superfamily; smart00487
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
L27 domain; pfam02828
L27 domain; pfam02828
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase; cd12081
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Apoptosis antagonizing transcription factor; pfam13339
L27 domain; pfam02828
L27 domain; pfam02828
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase; cd12081
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Apoptosis antagonizing transcription factor; pfam13339
L27 domain; pfam02828
L27 domain; pfam02828
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain of Calcium/calmodulin-dependent Serine protein Kinase; cd12081
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Flavin containing amine oxidoreductase; pfam01593
NAD(P)-binding Rossmann-like domain; pfam13450
Flavin containing amine oxidoreductase; pfam01593
Monoamine oxidase [Amino acid transport and metabolism]
NAD(P)-binding Rossmann-like domain; pfam13450
C-terminal cystine knot-like domain (CTCK); smart00041
Domains in hypothetical proteins in Drosophila, C. elegans and mammals. Occurs singly in some nucleoside diphosphate kinases; smart00676
Domains in hypothetical proteins in Drosophila, C. elegans and mammals. Occurs singly in some nucleoside diphosphate kinases; smart00676
Domains in hypothetical proteins in Drosophila, C. elegans and mammals. Occurs singly in some nucleoside diphosphate kinases; smart00676
FUN14 family; pfam04930
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; COG0475
Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; cl10482
Tubulin binding cofactor C; pfam07986
Domain in CAPs (cyclase-associated proteins) and X-linked retinitis pigmentosa 2 gene product; smart00673
Nucleoside diphosphate kinases (NDP kinases, NDPks): NDP kinases, responsible for the synthesis of nucleoside triphosphates (NTPs), are involved in numerous regulatory processes associated with proliferation, development, and differentiation. They are...; cl00335
Enhancer of polycomb-like; pfam10513
PHD-finger; pfam00628
PHD-zinc-finger like domain; pfam13832
Enhancer of polycomb-like; pfam10513
PHD-finger; pfam00628
PHD-zinc-finger like domain; pfam13832
SMP-30/Gluconolaconase/LRE-like region; pfam08450
SMP-30/Gluconolaconase/LRE-like region; pfam08450
ESSS subunit of NADH:ubiquinone oxidoreductase (complex I); pfam10183
ESSS subunit of NADH:ubiquinone oxidoreductase (complex I); pfam10183
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zinc finger domain; smart00547
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
glycine rich nucleic binding domain; smart00443
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zinc finger domain; smart00547
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
glycine rich nucleic binding domain; smart00443
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zinc finger domain; smart00547
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
glycine rich nucleic binding domain; smart00443
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zinc finger domain; smart00547
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
glycine rich nucleic binding domain; smart00443
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zinc finger domain; smart00547
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
glycine rich nucleic binding domain; smart00443
ubiquitin-activating enzyme E1; TIGR01408
Ubiquitin activating enzyme (E1), repeat 1. E1, a highly conserved small protein present universally in eukaryotic cells, is part of cascade to attach ubiquitin (Ub) covalently to substrate proteins. This cascade consists of activating (E1), conjugating; cd01491
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Ubiquitin activating enzyme (E1), repeat 2. E1, a highly conserved small protein present universally in eukaryotic cells, is part of cascade to attach ubiquitin (Ub) covalently to substrate proteins. This cascade consists of activating (E1), conjugating; cd01490
Repeat in ubiquitin-activating (UBA) protein; pfam02134
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
ubiquitin-activating enzyme E1; TIGR01408
Ubiquitin activating enzyme (E1), repeat 1. E1, a highly conserved small protein present universally in eukaryotic cells, is part of cascade to attach ubiquitin (Ub) covalently to substrate proteins. This cascade consists of activating (E1), conjugating; cd01491
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Ubiquitin activating enzyme (E1), repeat 2. E1, a highly conserved small protein present universally in eukaryotic cells, is part of cascade to attach ubiquitin (Ub) covalently to substrate proteins. This cascade consists of activating (E1), conjugating; cd01490
Repeat in ubiquitin-activating (UBA) protein; pfam02134
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-1 kinase; cd07873
cyclin-dependent kinase A; Provisional
Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-1 kinase; cd07873
cyclin-dependent kinase A; Provisional
Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-1 kinase; cd07873
cyclin-dependent kinase A; Provisional
Domain in ubiquitin-specific proteases; smart00695
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02674
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Ubiquitin domain of  Raf serine/threonine kinases; cd01816
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein kinase domain; pfam00069
Protein Kinases, catalytic domain; cl09925
Ubiquitin domain of  Raf serine/threonine kinases; cd01816
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein kinase domain; pfam00069
Protein Kinases, catalytic domain; cl09925
Ubiquitin domain of  Raf serine/threonine kinases; cd01816
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Synapsin N-terminal; pfam10581
Synapsin, N-terminal domain; pfam02078
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) [Coenzyme metabolism / Translation, ribosomal structure and biogenesis]; COG0189
Synapsin, ATP binding domain; pfam02750
Synapsin N-terminal; pfam10581
Synapsin, N-terminal domain; pfam02078
Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) [Coenzyme metabolism / Translation, ribosomal structure and biogenesis]; COG0189
Synapsin, ATP binding domain; pfam02750
NTR domain, TIMP subfamily; TIMPs, or tissue inibitors of metalloproteases, are essential regulators of extracellular matrix turnover and remodeling. They form complexes with matrix metalloproteases (MMPs) and inactivate them irreversibly by...; cd03585
Thrombospondin type 1 domain; pfam00090
Thrombospondin type 1 domain; pfam00090
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 domain; cl15278
Thrombospondin type 1 domain; pfam00090
Thrombospondin type 1 domain; pfam00090
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 domain; cl15278
Ets-domain; pfam00178
Ets-domain; pfam00178
Ets-domain; pfam00178
Prefoldin alpha subunit; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta...; cd00584
Prefoldin alpha subunit; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta...; cd00584
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have...; cd00119
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have...; cd00119
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
SSXRD motif; pfam09514
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
SSXRD motif; pfam09514
krueppel associated box; smart00349
SSXRD motif; pfam09514
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cl02581
SSXRD motif; pfam09514
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
krueppel associated box; smart00349
SSXRD motif; pfam09514
krueppel associated box; smart00349
krueppel associated box; smart00349
SSXRD motif; pfam09514
Transmembrane amino acid transporter protein; cl15776
23S rRNA methylase [Translation, ribosomal structure and biogenesis]; COG0293
FtsJ-like methyltransferase; pfam01728
23S rRNA methylase [Translation, ribosomal structure and biogenesis]; COG0293
FtsJ-like methyltransferase; pfam01728
23S rRNA methylase [Translation, ribosomal structure and biogenesis]; COG0293
FtsJ-like methyltransferase; pfam01728
MBOAT, membrane-bound O-acyltransferase family; pfam03062
MBOAT, membrane-bound O-acyltransferase family; pfam03062
MBOAT, membrane-bound O-acyltransferase family; pfam03062
MBOAT, membrane-bound O-acyltransferase family; pfam03062
Emopamil binding protein; pfam05241
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); pfam00076
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WASP-type EVH1 domain; cd01205
PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the...; cd00132
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Pre-SET motif; pfam05033
Proteins containing SET domain [General function prediction only]
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; cd07253
Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; pfam00903
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C; cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C; cd00202
Histone deacetylase 6, domain 1; cd11682
Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; COG0123
Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; COG0123
Histone deacetylase 6, domain 2; cd10003
Metaviral_G glycoprotein; pfam09595
Zn-finger in ubiquitin-hydrolases and other protein; pfam02148
Ral (Ras-like) family containing highly homologous RalA and RalB; cd04139
ProSAAS precursor; pfam07259
mitochondrial import inner membrane translocase subunit tim17; TIGR00980
mitochondrial import inner membrane translocase subunit tim17; TIGR00980
Domain with 2 conserved Trp (W) residues; smart00456
Domain with 2 conserved Trp (W) residues; smart00456
Domain with 2 conserved Trp (W) residues; smart00456
Domain with 2 conserved Trp (W) residues; smart00456
Domain with 2 conserved Trp (W) residues; smart00456
Domain with 2 conserved Trp (W) residues; smart00456
Domain with 2 conserved Trp (W) residues; smart00456
Nucleotide-sugar transporter; pfam04142
UDP-galactose transporter; TIGR00803
EamA-like transporter family; cl01037
Nucleotide-sugar transporter; pfam04142
UDP-galactose transporter; TIGR00803
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
OTU-like cysteine protease; pfam02338
OTU-like cysteine protease; pfam02338
OTU-like cysteine protease; pfam02338
OTU-like cysteine protease; pfam02338
Shal-type voltage-gated potassium channels; pfam11601
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
Domain of unknown function (DUF3399); pfam11879
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Domain of unknown function (DUF3338); pfam11819
Domain of unknown function (DUF3338); pfam11819
Domain of unknown function (DUF3338); pfam11819
Domain of unknown function (DUF3338); pfam11819
PRA1 family protein; pfam03208
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
DExH-box splicing factor binding site; pfam12656
KOW motif; pfam00467
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Membrane-associating domain; pfam01284
The PET domain of Prickle; cd09827
The first LIM domain of Prickle; cd09415
The second LIM domain of Prickle; cd09418
The third LIM domain of Prickle; cd09420
Membrane-associating domain; pfam01284
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Protein of unknown function (DUF812); pfam05667
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
Putative phosphatase regulatory subunit; pfam03370
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02660
ClC-3-like chloride channel proteins.  This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has...; cd03684
Voltage gated chloride channel; pfam00654
FOG: CBS domain [General function prediction only]
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of...; cd04591
ClC-3-like chloride channel proteins.  This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has...; cd03684
Voltage gated chloride channel; pfam00654
FOG: CBS domain [General function prediction only]
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of...; cd04591
ClC-3-like chloride channel proteins.  This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has...; cd03684
Voltage gated chloride channel; pfam00654
FOG: CBS domain [General function prediction only]
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of...; cd04591
A-kinase anchor protein 110 kDa; smart00807
A-kinase anchor protein 110 kDa; smart00807
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Pleckstrin homology (PH) domain; cd00821
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Diacylglycerol kinase catalytic domain (presumed); smart00046
Diacylglycerol kinase accessory domain; pfam00609
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Apx/Shroom domain ASD2; pfam08687
Transforming growth factor-beta (TGF-beta) family; smart00204
Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; cd04666
Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; cd04666
Ataxin-2 C-terminal region; pfam07145
Translation elongation factor EF-1alpha (GTPase) [Translation, ribosomal structure and biogenesis]; COG5256
Elongation Factor 1-alpha (EF1-alpha) protein family; cd01883
eRF3_II: domain II of the eukaryotic class II release factor (eRF3). In eukaryotes, translation termination is mediated by two interacting release factors, eRF1 and eRF3, which act as class I and II factors, respectively. eRF1 functions as an omnipotent...; cd04089
This family represents eEF1alpha-like C-terminal region of eRF3 homologous to the domain III of EF-Tu. eRF3 is a GTPase, which enhances the termination efficiency by stimulating the eRF1 activity in a GTP-dependent manner. The C-terminal region is...; cd03704
MAGE family; pfam01454
MAGE family; pfam01454
MAGE family; pfam01454
MAGE family; pfam01454
MAGE family; pfam01454
MAGE family; pfam01454
MAGE family; pfam01454
MAGE family; pfam01454
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cl02581
SSXRD motif; pfam09514
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
SSXRD motif; pfam09514
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
SSXRD motif; pfam09514
Sperm protein associated with nucleus, mapped to X chromosome; pfam07458
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
7 transmembrane receptor (rhodopsin family); pfam00001
Nucleosome assembly protein (NAP); pfam00956
(NAP-L) nucleosome assembly protein -L; Provisional; cl08298
ARID/BRIGHT DNA binding domain; smart01014
PHD-finger; pfam00628
JmjC domain, hydroxylase; pfam02373
C5HC2 zinc finger; pfam02928
PLU-1-like protein; pfam08429
PHD zinc finger; smart00249
Small domain found in the jumonji family of transcription factors; smart00545
ARID/BRIGHT DNA binding domain; pfam01388
PHD-finger; pfam00628
JmjC domain, hydroxylase; pfam02373
C5HC2 zinc finger; pfam02928
PLU-1-like protein; pfam08429
PHD zinc finger; smart00249
Protein of unknown function (DUF904); pfam06005
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor...; cd00171
Pleckstrin homology (PH) domain; cd00821
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor...; cd00171
Pleckstrin homology (PH) domain; cd00821
RecF/RecN/SMC N terminal domain; pfam02463
Eukaryotic SMC1 proteins; SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains.  Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal...; cd03275
SMC proteins Flexible Hinge Domain; smart00968
Eukaryotic SMC1 proteins; SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains.  Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal...; cd03275
RIB43A; pfam05914
RIB43A; pfam05914
RIB43A; pfam05914
3-ketoacyl-(acyl-carrier-protein) reductase; Validated; PRK05557
17hydroxysteroid dehydrogenase type 10 (HSD10)-like, classical (c) SDRs; cd05371
3-ketoacyl-(acyl-carrier-protein) reductase; Validated; PRK05557
17hydroxysteroid dehydrogenase type 10 (HSD10)-like, classical (c) SDRs; cd05371
Domain of Unknown Function (DUF908); pfam06012
Domain of Unknown Function (DUF913); pfam06025
Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis; smart00678
Domain of unknown function (DUF4414); pfam14377
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
PHD zinc finger; smart00249
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; cl15814
PHD zinc finger; smart00249
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; cl15814
PHD zinc finger; smart00249
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; cl15814
PHD zinc finger; smart00249
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; cl15814
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Oxidative-stress-responsive kinase 1 C terminal; pfam12202
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Oxidative-stress-responsive kinase 1 C terminal; pfam12202
Pre-rRNA-processing protein TSR2; pfam10273
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
FGD (faciogenital dysplasia protein) pleckstrin homology (PH) domain; cd01219
Protein present in Fab1, YOTB, Vac1, and EEA1; smart00064
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Pleckstrin homology (PH) domain; cd00821
ribosome biogenesis GTP-binding protein YlqF; TIGR03596
A circularly permuted subfamily of the Ras GTPases; cd04178
ribosome biogenesis GTP-binding protein YlqF; TIGR03596
A circularly permuted subfamily of the Ras GTPases; cd04178
Vault protein inter-alpha-trypsin domain; pfam08487
marine proteobacterial sortase target protein; TIGR03788
vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to...; cd01461
Inter-alpha-trypsin inhibitor heavy chain C-terminus; pfam06668
MAGE family; pfam01454
MAGE family; pfam01454
MAGE family; pfam01454
MAGE family; pfam01454
MAGE family; pfam01454
MAGE family; pfam01454
MAGE family; pfam01454
MAGE family; pfam01454
MAGE family; pfam01454
6-phosphofructo-2-kinase; pfam01591
AAA domain; pfam13671
Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; cd07067
Human Ape2-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; cd09088
GRF zinc finger; pfam06839
5-aminolevulinate synthase presequence; pfam09029
7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; COG0156
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); cd06454
5-aminolevulinate synthase presequence; pfam09029
7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; COG0156
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); cd06454
5-aminolevulinate synthase presequence; pfam09029
7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; COG0156
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); cd06454
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
GAGE protein; pfam05831
MAGE family; pfam01454
Zn-finger in ubiquitin-hydrolases and other protein; pfam02148
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02660
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
Rag GTPase, subfamily of Ras-related GTPases, includes Ras-related GTP-binding proteins A and B; cd11384
Gtr1/RagA G protein conserved region; pfam04670
Rag GTPase, subfamily of Ras-related GTPases, includes Ras-related GTP-binding proteins A and B; cd11384
Gtr1/RagA G protein conserved region; pfam04670
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Ubiquitin-like domain of hPLIC-1 and hPLIC2; cd01808
Ubiquitin family; pfam00240
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Spin/Ssty Family; pfam02513
Spin/Ssty Family; pfam02513
Spin/Ssty Family; pfam02513
Spin/Ssty Family; pfam02513
Spin/Ssty Family; pfam02513
Spin/Ssty Family; pfam02513
Spin/Ssty Family; pfam02513
Spin/Ssty Family; pfam02513
Spin/Ssty Family; pfam02513
Spin/Ssty Family; pfam02513
Spin/Ssty Family; pfam02513
Spin/Ssty Family; pfam02513
Spin/Ssty Family; pfam02513
Spin/Ssty Family; pfam02513
Spin/Ssty Family; pfam02513
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; COG0154
Amidase; cl11426
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Spin/Ssty Family; pfam02513
Spin/Ssty Family; pfam02513
Spin/Ssty Family; pfam02513
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Collybistin pleckstrin homology (PH) domain; cd01224
Src homology 3 domain of the Rho guanine nucleotide exchange factor ARHGEF9; cd11975
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Collybistin pleckstrin homology (PH) domain; cd01224
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Collybistin pleckstrin homology (PH) domain; cd01224
WTX protein; pfam09422
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
SOCS box; pfam07525
Myotubularin-related; pfam06602
Myotubularin Y_phosphatase-like; pfam13849
Zinc finger-containing protein; pfam10146
Zinc finger-containing protein; pfam10146
Zinc finger-containing protein; pfam10146
Zinc finger-containing protein; pfam10146
Zc3h12a-like Ribonuclease NYN domain; pfam11977
Las1-like; pfam04031
Las1-like; pfam04031
Las1-like; pfam04031
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
Ezrin/radixin/moesin family; pfam00769
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Multicopper oxidase; pfam07731
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Multicopper oxidase; pfam07731
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Multicopper oxidase; pfam07731
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Androgen receptor; pfam02166
DNA-binding domain of androgen receptor (AR) is composed of two C4-type zinc fingers; cd07173
Ligand binding domain of the nuclear receptor androgen receptor, ligand activated transcription regulator; cd07073
DNA-binding domain of androgen receptor (AR) is composed of two C4-type zinc fingers; cd07173
Ligand binding domain of the nuclear receptor androgen receptor, ligand activated transcription regulator; cd07073
The Bin/Amphiphysin/Rvs (BAR) domain of Oligophrenin-1; cd07633
Oligophrenin Pleckstrin homology (PH) domain; cd01249
RhoGAP_Graf: GTPase-activator protein (GAP) domain for Rho-like GTPases found in GRAF (GTPase regulator associated with focal adhesion kinase); Graf is a multi-domain protein, containing SH3 and PH domains, that binds focal adhesion kinase and influences...; cd04374
GTPase-activator protein for Rho-like GTPases; smart00324
Yip1 domain; cl12048
Yip1 domain; cl12048
SAM domain of DLC1,2-like subfamily; cd09538
RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when...; cl02570
GTPase-activator protein for Rho-like GTPases; smart00324
C-terminal lipid-binding START domain of mammalian STARD8 and related proteins, which also have an N-terminal Rho GTPase-activating protein (RhoGAP) domain; cd08907
RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when...; cl02570
GTPase-activator protein for Rho-like GTPases; smart00324
C-terminal lipid-binding START domain of mammalian STARD8 and related proteins, which also have an N-terminal Rho GTPase-activating protein (RhoGAP) domain; cd08907
RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when...; cl02570
GTPase-activator protein for Rho-like GTPases; smart00324
C-terminal lipid-binding START domain of mammalian STARD8 and related proteins, which also have an N-terminal Rho GTPase-activating protein (RhoGAP) domain; cd08907
Receptor Binding Domain of Ephrin B; cd10426
Fanconi anemia ID complex proteins FANCI and FANCD2; cl17018
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Fanconi anemia ID complex proteins FANCI and FANCD2; cl17018
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Fanconi anemia ID complex proteins FANCI and FANCD2; cl17018
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cd00184
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cd00184
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cd00184
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; cd07987
OTU-like cysteine protease; pfam02338
TAP42-like family; pfam04177
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; cd07987
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; cd07987
7 transmembrane receptor (rhodopsin family); pfam00001
Arrestin (or S-antigen), N-terminal domain; pfam00339
Arrestin (or S-antigen), C-terminal domain; smart01017
Rab GTPase; Provisional
Rab GTPase family 6 (Rab6); cd01861
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Kinesin motor domain, KIF4-like subfamily. Members of this group seem to perform a variety of functions, and have been implicated in neuronal organelle transport and chromosome segregation during mitosis. This catalytic (head) domain has ATPase activity...; cd01372
Kinesin motor, catalytic domain. ATPase; smart00129
Glycerophosphodiester phosphodiesterase domain of mammalian glycerophosphodiester phosphodiesterase GDE3 and similar proteins; cd08609
Glycerophosphodiester phosphodiesterase domain of mammalian glycerophosphodiester phosphodiesterase GDE3 and similar proteins; cd08609
Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; COG0584
Glycerophosphodiester phosphodiesterase domain of mammalian glycerophosphodiester phosphodiesterase GDE3 and similar proteins; cd08609
Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; COG0584
Glycerophosphodiester phosphodiesterase domain of mammalian glycerophosphodiester phosphodiesterase GDE3 and similar proteins; cd08609
Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; COG0584
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ-associated domain of NMDA receptors; pfam10600
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain of Disks Large homolog 3; cd12029
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain of Disks Large homolog 3; cd12029
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
Src Homology 3 domain of Disks Large homolog 3; cd12029
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
Meiosis protein SPO22/ZIP4 like; pfam08631
Meiosis protein SPO22/ZIP4 like; pfam08631
cationic amino acid transport permease; TIGR00906
Spore germination protein; cl15802
Spore germination protein; cl15802
C-terminus of AA_permease; pfam13906
cationic amino acid transport permease; TIGR00906
Spore germination protein; cl15802
Spore germination protein; cl15802
C-terminus of AA_permease; pfam13906
The Phox Homology domain, a phosphoinositide binding module; cl02563
The phosphoinositide binding Phox Homology domain of Sorting Nexin 12; cd07294
The phosphoinositide binding Phox Homology domain of Sorting Nexin 12; cd07294
The Phox Homology domain, a phosphoinositide binding module; cl02563
The Phox Homology domain, a phosphoinositide binding module; cl02563
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
Interleukin-6 receptor alpha chain, binding; cl12153
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Transcription mediator complex subunit Med12; pfam09497
Eukaryotic Mediator 12 subunit domain; pfam12145
Eukaryotic Mediator 12 catenin-binding domain; pfam12144
Carboxylesterase family; pfam00135
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Carboxylesterase family; pfam00135
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Carboxylesterase family; pfam00135
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Connexin; pfam00029
Gap junction channel protein cysteine-rich domain; smart01089
Connexin; pfam00029
Gap junction channel protein cysteine-rich domain; smart01089
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
Ribosomal protein L24e/L24 is a ribosomal protein found in eukaryotes (L24) and in archaea (L24e, distinct from archaeal L24). L24e/L24 is located on the surface of the large subunit, adjacent to proteins L14 and L3, and near the translation factor...; cl00909
MYM-type Zinc finger with FCS sequence motif; pfam06467
metallochaperone-like domain; smart00746
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
Ribosomal protein L24e/L24 is a ribosomal protein found in eukaryotes (L24) and in archaea (L24e, distinct from archaeal L24). L24e/L24 is located on the surface of the large subunit, adjacent to proteins L14 and L3, and near the translation factor...; cl00909
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
Domain of unknown function (DUF3504); pfam12012
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
Ribosomal protein L24e/L24 is a ribosomal protein found in eukaryotes (L24) and in archaea (L24e, distinct from archaeal L24). L24e/L24 is located on the surface of the large subunit, adjacent to proteins L14 and L3, and near the translation factor...; cl00909
MYM-type Zinc finger with FCS sequence motif; pfam06467
metallochaperone-like domain; smart00746
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
Domain of unknown function (DUF3504); pfam12012
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
Ribosomal protein L24e/L24 is a ribosomal protein found in eukaryotes (L24) and in archaea (L24e, distinct from archaeal L24). L24e/L24 is located on the surface of the large subunit, adjacent to proteins L14 and L3, and near the translation factor...; cl00909
MYM-type Zinc finger with FCS sequence motif; pfam06467
metallochaperone-like domain; smart00746
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
Domain of unknown function (DUF3504); pfam12012
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
NOPS (NUC059) domain; pfam08075
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
NOPS (NUC059) domain; pfam08075
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
NOPS (NUC059) domain; pfam08075
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
NOPS (NUC059) domain; pfam08075
CHORD; pfam04968
CHORD; pfam04968
p23_like domain similar to the C-terminal (tail) domain of vertebrate Melusin and related proteins. Melusin's tail domain interacts with the cytoplasmic domain of beta1-A and beta1-D isoforms of beta1 integrin, it does not bind other integrin beta...; cd06488
TATA box-binding protein binding; pfam09247
Protein of unknown function (DUF3591); pfam12157
Bromodomain, TFIID-like subfamily. Human TAFII250 (or TAF250) is the largest subunit of TFIID, a large multi-domain complex, which initiates the assembly of the transcription machinery. TAFII250 contains two bromodomains that specifically bind to...; cd05511
Bromodomain, TFIID-like subfamily. Human TAFII250 (or TAF250) is the largest subunit of TFIID, a large multi-domain complex, which initiates the assembly of the transcription machinery. TAFII250 contains two bromodomains that specifically bind to...; cd05511
TATA box-binding protein binding; pfam09247
Protein of unknown function (DUF3591); pfam12157
Bromodomain, TFIID-like subfamily. Human TAFII250 (or TAF250) is the largest subunit of TFIID, a large multi-domain complex, which initiates the assembly of the transcription machinery. TAFII250 contains two bromodomains that specifically bind to...; cd05511
Bromodomain, TFIID-like subfamily. Human TAFII250 (or TAF250) is the largest subunit of TFIID, a large multi-domain complex, which initiates the assembly of the transcription machinery. TAFII250 contains two bromodomains that specifically bind to...; cd05511
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13432
TPR repeat; pfam13414
Tetratricopeptide repeat; pfam00515
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Glycosyl transferase family 41; pfam13844
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13432
TPR repeat; pfam13414
Tetratricopeptide repeat; pfam00515
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Glycosyl transferase family 41; pfam13844
SprT homologues; smart00731
SprT-like family; pfam10263
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
Retrotransposon gag protein; pfam03732
Translationally controlled tumour protein; cl08291
PPIC-type PPIASE domain; pfam00639
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
40S ribosomal protein S4; Provisional
RS4NT (NUC023) domain; pfam08071
S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; cd00165
Ribosomal family S4e; pfam00900
CITED; pfam04487
CITED; pfam04487
CITED; pfam04487
CITED; pfam04487
Arginase-like and histone-like hydrolases; cl17011
Arginase-like and histone-like hydrolases; cl17011
Histone deacetylase 8 (HDAC8); cd10000
Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; COG0123
Arginase-like and histone-like hydrolases; cl17011
Arginase-like and histone-like hydrolases; cl17011
Arginase-like and histone-like hydrolases; cl17011
Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; COG0123
Arginase-like and histone-like hydrolases; cl17011
Arginase-like and histone-like hydrolases; cl17011
Glycosyl hydrolases family 15; pfam00723
Glycosyl hydrolases family 15; pfam00723
Glycosyl hydrolases family 15; pfam00723
Glycosyl hydrolases family 15; pfam00723
Glycosyl hydrolases family 15; pfam00723
Glycosyl hydrolases family 15; pfam00723
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
(NAP-L) nucleosome assembly protein -L; Provisional; cl08298
Nucleosome assembly protein (NAP); pfam00956
Caudal like protein activation region; pfam04731
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Golgin subfamily A member 7/ERF4 family; pfam10256
universal minicircle sequence binding protein (UMSBP); Provisional
monocarboxylate transporter 1; TIGR00892
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
ABC transporter transmembrane region; pfam00664
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; COG5265
ATM1 is an ABC transporter that is expressed in the mitochondria.  Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to...; cd03253
Phosphoribosyl transferase (PRT)-type I domain; cd06223
DHHC palmitoyltransferase; pfam01529
DHHC palmitoyltransferase; pfam01529
MAGE family; pfam01454
MAGE family; pfam01454
Polysaccharide biosynthesis; pfam04669
Herpesvirus transcription activation factor (transactivator); pfam03326
MAGE family; pfam01454
MAGE family; pfam01454
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
ADDz domain of ATRX (alpha-thalassemia/mental retardation, X-linked); cd11726
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
ADDz domain of ATRX (alpha-thalassemia/mental retardation, X-linked); cd11726
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; cd02947
OST3 / OST6 family; pfam04756
Cytochrome C oxidase chain VIIb. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; cd01403
Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; cd07067
Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; cd07067
Cation transport ATPase [Inorganic ion transport and metabolism]; COG2217
Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; cd00371
Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; cd00371
Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; cd00371
Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; cd00371
Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; cd00371
Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; cd00371
copper-(or silver)-translocating P-type ATPase; TIGR01511
E1-E2 ATPase; pfam00122
Haloacid Dehalogenase-like Hydrolases; cl11391
Phosphoglycerate kinase; pfam00162
Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; cd00318
TATA Binding Protein (TBP) Associated Factor 9 (TAF9) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex; cd07979
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
universal minicircle sequence binding protein (UMSBP); Provisional
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
BRICHOS domain; pfam04089
BRICHOS domain; pfam04089
T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA...; cd00182
T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA...; cd00182
T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA...; cl00145
Domain of unknown function (DUF1693); pfam07984
Domain of unknown function (DUF1693); pfam07984
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional...; cd05529
Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine; cl02556
HMG14 and HMG17; pfam01101
Glutaredoxin (GRX) family, SH3BGR (SH3 domain binding glutamic acid-rich protein) subfamily; a recently-identified subfamily composed of SH3BGR and similar proteins possessing significant sequence similarity to GRX, but without a redox active CXXC motif; cd03030
Found in Pit-Oct-Unc transcription factors; smart00352
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Serine/Threonine protein kinases, catalytic domain; smart00220
N-terminal catalytic domain of the Protein Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase; cd05582
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Homeodomain; smart00389
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain; smart00389
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Apolipoprotein O; pfam09769
DNA polymerase III subunits gamma and tau; Validated
Zfx / Zfy transcription activation region; pfam04704
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
chromosome segregation protein SMC, primarily archaeal type; TIGR02169
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
SKI/SNO/DAC family; pfam02437
SKI/SNO/DAC family; pfam02437
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch motif; pfam01344
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Cadherin repeat-like domain; cl15786
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Protocadherin; pfam08374
Cadherin repeat-like domain; cl15786
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Protocadherin; pfam08374
Cadherin repeat-like domain; cl15786
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Protocadherin; pfam08374
Cadherin repeat-like domain; cl15786
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Protocadherin; pfam08374
Cadherin repeat-like domain; cl15786
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Protocadherin; pfam08374
Cadherin repeat-like domain; cl15786
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Protocadherin; pfam08374
Cadherin repeat-like domain; cl15786
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Protocadherin; pfam08374
Cadherin repeat-like domain; cl15786
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Protocadherin; pfam08374
Nucleosome assembly protein (NAP); pfam00956
(NAP-L) nucleosome assembly protein -L; Provisional; cl08298
Diaphanous GTPase-binding Domain; pfam06371
Diaphanous FH3 Domain; pfam06367
Formin Homology 2 Domain; smart00498
Formin Homology 2 Domain; pfam02181
Diaphanous GTPase-binding Domain; pfam06371
Diaphanous FH3 Domain; pfam06367
Formin Homology 2 Domain; smart00498
Formin Homology 2 Domain; pfam02181
RPA2_DBD_D: A subfamily of OB folds corresponding to the OB fold of the central ssDNA-binding domain (DBD)-D of human RPA2 (also called RPA32). RPA2 is a subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which appears...; cd04478
Replication protein A C terminal; pfam08784
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
The BRICHOS domain is found in a variety of proteins implicated in dementia, respiratory distress and cancer; smart01039
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), TM4SF2_6_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment...; cd03161
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
HYR domain; pfam02494
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Domain of unknown function (DUF4174); pfam13778
C2 domain first repeat present in Synaptotagmin-like proteins 4 and 5; cd04029
C2 domain second repeat present in Synaptotagmin-like proteins 1-4; cd04020
C2 domain first repeat present in Synaptotagmin-like proteins 4 and 5; cd04029
C2 domain second repeat present in Synaptotagmin-like proteins 1-4; cd04020
C2 domain first repeat present in Synaptotagmin-like proteins 4 and 5; cd04029
C2 domain second repeat present in Synaptotagmin-like proteins 1-4; cd04020
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Hinge domain of cleavage stimulation factor subunit 2; pfam14327
Transcription termination and cleavage factor C-terminal; pfam14304
Ferric reductase like transmembrane component; pfam01794
NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX...; cd06186
Ferric reductase like transmembrane component; pfam01794
NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX...; cd06186
XK-related protein; pfam09815
GTPase SAR1 and related small G proteins [General function prediction only]
Arl2-like protein 1 (Arl2l1) and Arl13; cd04161
GTPase SAR1 and related small G proteins [General function prediction only]
Arl2-like protein 1 (Arl2l1) and Arl13; cd04161
GTPase SAR1 and related small G proteins [General function prediction only]
Arl2-like protein 1 (Arl2l1) and Arl13; cd04161
SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; COG2265
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; COG2265
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; COG2265
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; COG2265
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Mis6; pfam07778
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
TATA Binding Protein (TBP) Associated Factor 7 (TAF7) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex; cd08047
TATA Binding Protein (TBP) Associated Factor 7 (TAF7) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex; cd08047
Tim10/DDP family zinc finger; pfam02953
Tim10/DDP family zinc finger; pfam02953
Tec pleckstrin homology (PH) domain; cd01238
Bruton's tyrosine kinase Cys-rich motif; smart00107
Src Homology 3 domain of Bruton's tyrosine kinase; cd11906
Src homology 2 (SH2) domain found  in Tec protein, Bruton's tyrosine kinase (Btk); cd10397
Catalytic domain of the Protein Tyrosine Kinases, Bruton's tyrosine kinase and Bone marrow kinase on the X chromosome; cd05113
Protein tyrosine kinase; pfam07714
60S ribosomal protein L36a; Provisional
60S ribosomal protein L36a; Provisional
60S ribosomal protein L36a; Provisional
60S ribosomal protein L36a; Provisional
The enzymes of glycosyl hydrolase family 31 (GH31) occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase; cl11402
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNPHF zinc finger; pfam08080
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNPHF zinc finger; pfam08080
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
NADH dehydrogenase subunit C; Validated
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Armadillo-like; pfam04826
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Armadillo-like; pfam04826
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Armadillo-like; pfam04826
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo-like; pfam04826
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Tap, RNA-binding; pfam09162
U1-like zinc finger; smart00451
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Tap, RNA-binding; pfam09162
Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many...; cd00780
TAP C-terminal domain; pfam03943
Tap, RNA-binding; pfam09162
Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many...; cd00780
TAP C-terminal domain; pfam03943
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
Armadillo-like; pfam04826
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
SOCS (suppressors of cytokine signaling) box of Rab40-like proteins. Rab40 is part of the Rab family of small GTP-binding proteins that form the largest family within the Ras superfamily. Rab proteins regulate vesicular trafficking pathways, behaving as...; cd03742
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Brain expressed X-linked like family; pfam04538
Tap, RNA-binding; pfam09162
Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many...; cd00780
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
SOCS (suppressors of cytokine signaling) box of Rab40-like proteins. Rab40 is part of the Rab family of small GTP-binding proteins that form the largest family within the Ras superfamily. Rab proteins regulate vesicular trafficking pathways, behaving as...; cd03742
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
Brain expressed X-linked like family; pfam04538
MRG; pfam05712
MRG; pfam05712
MRG; pfam05712
MRG; pfam05712
MRG; pfam05712
MRG; pfam05712
MRG; pfam05712
MRG; pfam05712
MRG; pfam05712
MRG; pfam05712
MRG; pfam05712
MRG; pfam05712
MRG; pfam05712
MRG; pfam05712
MRG; pfam05712
MRG; pfam05712
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Myelin proteolipid protein (PLP or lipophilin); pfam01275
Myelin proteolipid protein (PLP or lipophilin); pfam01275
Myelin proteolipid protein (PLP or lipophilin); pfam01275
Rab GTPase family 9 (Rab9); cd04116
Rab GTPase; Provisional
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cl00074
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cl00074
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Immunoglobulin domain; cl11960
Second immunoglobulin (Ig)-like domain of interleukin-1 receptor (IL1R) and similar proteins; cd05757
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Toll - interleukin 1 - resistance; smart00255
Zinc finger domain; smart00547
Catalytic domain of Class III myosin-like Protein Serine/Threonine Kinases; cd06608
Serine/Threonine protein kinases, catalytic domain; smart00220
CNH domain; cl02434
alpha-1-antitrypsin_like. This family contains a variety of different members of clade A of the serpin superfamily. They include the classical serine proteinase inhibitors, alpha-1-antitrypsin and alpha-1-antichymotrypsin, protein C inhibitor; cd02056
serpin-like protein; Provisional
Mutated melanoma-associated antigen 1 (MUM-1) is a melanoma-associated antigen (MAA).  MUM-1 belongs to the mutated or aberrantly expressed type of MAAs, along with antigens such as CDK4, beta-catenin, gp100-in4, p15, and N-acetylglucosaminyltransferase...; cd06080
Mutated melanoma-associated antigen 1 (MUM-1) is a melanoma-associated antigen (MAA).  MUM-1 belongs to the mutated or aberrantly expressed type of MAAs, along with antigens such as CDK4, beta-catenin, gp100-in4, p15, and N-acetylglucosaminyltransferase...; cd06080
Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; cl09930
replication factor-a protein 1 (rpa1); TIGR00617
Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; cl09930
replication factor-a protein 1 (rpa1); TIGR00617
PA _GRAIL_like: Protease-associated (PA) domain GRAIL-like. This group includes PA domain containing E3 (ubiquitin ligases) similar to human GRAIL (gene related to anergy in lymphocytes) protein. Proteins in this group contain a C3H2C3 RING finger. E3...; cd02122
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
PA _GRAIL_like: Protease-associated (PA) domain GRAIL-like. This group includes PA domain containing E3 (ubiquitin ligases) similar to human GRAIL (gene related to anergy in lymphocytes) protein. Proteins in this group contain a C3H2C3 RING finger. E3...; cd02122
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
GRAM domain; pfam02893
GRAM domain; pfam02893
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
GRAM domain; pfam02893
GRAM domain; pfam02893
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
PMP-22/EMP/MP20/Claudin family; cl15797
PMP-22/EMP/MP20/Claudin family; cl15797
PMP-22/EMP/MP20/Claudin family; cl15797
Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; cd00075
CW-type Zinc Finger; pfam07496
Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; cd00075
CW-type Zinc Finger; pfam07496
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Nsp1-like C-terminal region; pfam05064
pre-RNA processing PIH1/Nop17; pfam08190
pre-RNA processing PIH1/Nop17; pfam08190
ribose-phosphate pyrophosphokinase; Provisional
N-terminal domain of ribose phosphate pyrophosphokinase; pfam13793
Phosphoribosyl transferase (PRT)-type I domain; cd06223
Phosphoribosyl transferase (PRT)-type I domain; cd06223
TSC-22/dip/bun family; pfam01166
TSC-22/dip/bun family; pfam01166
TSC-22/dip/bun family; pfam01166
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Domain in SPla and the RYanodine Receptor; smart00449
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeat; pfam00023
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Peptidase family C54; pfam03416
Peptidase family C54; pfam03416
Collagen triple helix repeat (20 copies); pfam01391
C-terminal tandem repeated domain in type 4 procollagen; pfam01413
C-terminal tandem repeated domain in type 4 procollagen; pfam01413
C-terminal tandem repeated domain in type 4 procollagen; pfam01413
C-terminal tandem repeated domain in type 4 procollagen; pfam01413
C-terminal tandem repeated domain in type 4 procollagen; pfam01413
C-terminal tandem repeated domain in type 4 procollagens; smart00111
C-terminal tandem repeated domain in type 4 procollagen; pfam01413
C-terminal tandem repeated domain in type 4 procollagens; smart00111
Pleckstrin homology-like domain; cl00273
Insulin receptor substrate (IRS) Phosphotyrosine-binding domain(PTB); cd01204
Ligand-binding domain of membrane guanylyl cyclases (GC-D, GC-E, and GC-F) that are specifically expressed in sensory tissues; cd06371
Receptor family ligand binding region; pfam01094
Protein Kinases, catalytic domain; cl09925
Adenylyl- / guanylyl cyclase, catalytic domain; smart00044
Heme NO binding associated; pfam07701
cyclase homology domain; cd07302
Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many...; cd00780
Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many...; cd00780
Nuclear transport factor 2 (NTF2) domain plays an important role in the trafficking of macromolecules, ions and small molecules between the cytoplasm and nucleus. This bi-directional transport of macromolecules across the nuclear envelope requires many...; cd00780
long-chain-fatty-acid-CoA ligase family protein
AMP-binding enzyme; pfam00501
long-chain-fatty-acid-CoA ligase family protein
AMP-binding enzyme; pfam00501
AMMECR1; cl00911
AMMECR1; pfam01871
AMMECR1; pfam01871
Retrotransposon gag protein; pfam03732
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the...; cd01093
Catalytic domain of the Protein Serine/Threonine Kinase, Group I p21-activated kinase; cd06647
Serine/Threonine protein kinases, catalytic domain; smart00220
PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the...; cd01093
Catalytic domain of the Protein Serine/Threonine Kinase, Group I p21-activated kinase; cd06647
Serine/Threonine protein kinases, catalytic domain; smart00220
PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the...; cd01093
Catalytic domain of the Protein Serine/Threonine Kinase, Group I p21-activated kinase; cd06647
Serine/Threonine protein kinases, catalytic domain; smart00220
PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the...; cd01093
Catalytic domain of the Protein Serine/Threonine Kinase, Group I p21-activated kinase; cd06647
Serine/Threonine protein kinases, catalytic domain; smart00220
PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the...; cd01093
Catalytic domain of the Protein Serine/Threonine Kinase, Group I p21-activated kinase; cd06647
Serine/Threonine protein kinases, catalytic domain; smart00220
PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the...; cd01093
Catalytic domain of the Protein Serine/Threonine Kinase, Group I p21-activated kinase; cd06647
Serine/Threonine protein kinases, catalytic domain; smart00220
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction; cd00044
Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are...; cd00214
C2 domain present in Calpain proteins; cd04046
Ubiquitin-like domain of DCX; cd01617
Ubiquitin-like domain of DCX; cd01617
Ubiquitin-like domain of DCX; cd01617
Ubiquitin-like domain of DCX; cd01617
Ubiquitin-like domain of DCX; cd01617
Ubiquitin-like domain of DCX; cd01617
Ubiquitin-like domain of DCX; cd01617
Ubiquitin-like domain of DCX; cd01617
Ubiquitin-like domain of DCX; cd01617
Ubiquitin-like domain of DCX; cd01617
Glycosyltransferase family 28 C-terminal domain; pfam04101
OTU-like cysteine protease; pfam02338
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
Glycosyltransferase family 28 C-terminal domain; pfam04101
Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; cl10013
Glycosyltransferase family 28 C-terminal domain; pfam04101
Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; cl10013
OTU-like cysteine protease; pfam02338
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; cl10013
OTU-like cysteine protease; pfam02338
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
OTU-like cysteine protease; pfam02338
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
OTU-like cysteine protease; pfam02338
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
transient-receptor-potential calcium channel protein; TIGR00870
Transient receptor ion channel II; pfam08344
Lipoma HMGIC fusion partner-like protein; pfam10242
Angiomotin C terminal; pfam12240
Angiomotin C terminal; pfam12240
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
Interleukin-6 receptor alpha chain, binding; pfam09240
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]; COG5069
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]; COG5069
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
7 transmembrane receptor (rhodopsin family); pfam00001
Na(+)- and Cl(-)-dependent beta-alanine transporter ATB0+; solute-binding domain; cd11501
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch motif; pfam01344
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch motif; pfam01344
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch motif; pfam01344
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch motif; pfam01344
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch motif; pfam01344
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch motif; pfam01344
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Domain of unknown function (DUF3398); pfam11878
Pleckstrin homology (PH) domain; cd00821
C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins; cd08697
Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 11; cd11700
Interleukin-6 receptor alpha chain, binding; pfam09240
Zinc finger, C3HC4 type (RING finger); pfam13923
Ring finger; smart00184
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
ATP-dependent protease La (LON) domain; pfam02190
Zinc finger, C3HC4 type (RING finger); pfam13923
Ring finger; smart00184
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
ATP-dependent protease La (LON) domain; pfam02190
Cytochrome b5-like Heme/Steroid binding domain; pfam00173
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Protein of unknown function (DUF3469); pfam11952
Double-stranded RNA binding motif; pfam00035
glycine rich nucleic binding domain; smart00443
R3H domain of the NF-kappaB-repression factor (NRF). NRF is a nuclear inhibitor of NF-kappaB proteins that can silence the IFNbeta promoter via binding to a negative regulatory element (NRE). Beside R3H NRF also contains a G-patch domain. The name of the...; cd02640
Double-stranded RNA binding motif; pfam00035
glycine rich nucleic binding domain; smart00443
R3H domain of the NF-kappaB-repression factor (NRF). NRF is a nuclear inhibitor of NF-kappaB proteins that can silence the IFNbeta promoter via binding to a negative regulatory element (NRE). Beside R3H NRF also contains a G-patch domain. The name of the...; cd02640
Double-stranded RNA binding motif; pfam00035
glycine rich nucleic binding domain; smart00443
R3H domain of the NF-kappaB-repression factor (NRF). NRF is a nuclear inhibitor of NF-kappaB proteins that can silence the IFNbeta promoter via binding to a negative regulatory element (NRE). Beside R3H NRF also contains a G-patch domain. The name of the...; cd02640
CDC/Septin GTPase family; cd01850
Septin; pfam00735
CDC/Septin GTPase family; cd01850
Septin; pfam00735
CDC/Septin GTPase family; cd01850
Septin; pfam00735
CDC/Septin GTPase family; cd01850
Septin; pfam00735
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
Ribosomal L39 protein; pfam00832
Smg-4/UPF3 family; pfam03467
Smg-4/UPF3 family; pfam03467
Zinc finger C-x8-C-x5-C-x3-H type (and similar); pfam00642
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
28 kDa A-kinase anchor; pfam14469
28 kDa A-kinase anchor; pfam14469
28 kDa A-kinase anchor; pfam14469
28 kDa A-kinase anchor; pfam14469
Ras-induced vulval development antagonist; pfam06047
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Sodium / potassium ATPase beta chain; cl08255
Sodium / potassium ATPase beta chain; cl08255
Lysosome-associated membrane glycoprotein (Lamp); pfam01299
Lysosome-associated membrane glycoprotein (Lamp); pfam01299
Lysosome-associated membrane glycoprotein (Lamp); pfam01299
Cullin family; pfam00888
Cullin; smart00182
Cullin protein neddylation domain; pfam10557
Cullin family; pfam00888
Cullin; smart00182
Cullin protein neddylation domain; pfam10557
N-terminal domain of multiple copies T cell malignancies 1 and related proteins; cd11609
Predicted RNA-binding protein (contains PUA domain) [Translation, ribosomal structure and biogenesis]
PUA domain; cl00607
N-terminal domain of multiple copies T cell malignancies 1 and related proteins; cd11609
Predicted RNA-binding protein (contains PUA domain) [Translation, ribosomal structure and biogenesis]
PUA domain; cl00607
Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; COG0334
Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; pfam02812
NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; cd01076
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the GluR3 subunit of the AMPA receptor; cd06387
Receptor family ligand binding region; pfam01094
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Ligand-gated ion channel; pfam00060
Eukaryotic homologues of bacterial periplasmic substrate binding proteins; smart00079
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the GluR3 subunit of the AMPA receptor; cd06387
Receptor family ligand binding region; pfam01094
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Ligand-gated ion channel; pfam00060
Eukaryotic homologues of bacterial periplasmic substrate binding proteins; smart00079
Type 1 periplasmic binding fold superfamily; cl10011
Transcription- and export-related complex subunit; pfam11732
Transcription factor/nuclear export subunit protein 2; pfam11262
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Zinc finger, C3HC4 type (RING finger); pfam13920
Zinc finger, C3HC4 type (RING finger); pfam13923
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Zinc finger, C3HC4 type (RING finger); pfam13920
Zinc finger, C3HC4 type (RING finger); pfam13923
STAG domain; pfam08514
STAG domain; pfam08514
STAG domain; pfam08514
STAG domain; pfam08514
Src homology 2 (SH2) domain found in SLAM-associated protein (SAP) 1a; cd10400
Src homology 2 (SH2) domain found in SLAM-associated protein (SAP) 1a; cd10400
Teneurin Intracellular Region; pfam06484
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Rhs family protein [Cell envelope biogenesis, outer membrane]; COG3209
YD repeat (two copies); TIGR01643
RHS repeat-associated core domain; TIGR03696
Teneurin Intracellular Region; pfam06484
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Rhs family protein [Cell envelope biogenesis, outer membrane]; COG3209
YD repeat (two copies); TIGR01643
RHS repeat-associated core domain; TIGR03696
Teneurin Intracellular Region; pfam06484
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Rhs family protein [Cell envelope biogenesis, outer membrane]; COG3209
YD repeat (two copies); TIGR01643
RHS repeat-associated core domain; TIGR03696
DNA polymerase III subunits gamma and tau; Provisional
E3 ubiquitin-protein ligase SspH2; Provisional
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Actin; pfam00022
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cl17037
DNA-binding domain; pfam13892
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
HAND; pfam09110
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
SLIDE; pfam09111
DNA-binding domain; pfam13892
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
HAND; pfam09110
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
SLIDE; pfam09111
Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins; cd09093
RhoGAP_OCRL1: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate...; cd04380
GTPase-activator protein for Rho-like GTPases; smart00324
Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins; cd09093
RhoGAP_OCRL1: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate...; cd04380
GTPase-activator protein for Rho-like GTPases; smart00324
Creatinase/Prolidase N-terminal domain; pfam01321
Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; COG0006
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; cd01085
Lymphocyte signaling adaptor protein; pfam12485
Src homology 3 domain of Sam And SH3 Domain Containing Protein 3; cd11968
SAM domain of SASH3 subfamily; cd09560
Sterile alpha motif; smart00454
DHHC palmitoyltransferase; pfam01529
DHHC palmitoyltransferase; pfam01529
Utp14 protein; pfam04615
Utp14 protein; pfam04615
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Transcription factor protein N terminal; pfam12310
Ets-domain; pfam00178
Transcription factor protein N terminal; pfam12310
Ets-domain; pfam00178
Pyridine nucleotide-disulphide oxidoreductase; pfam07992
Pyridine nucleotide-disulphide oxidoreductase; pfam07992
Pyridine nucleotide-disulphide oxidoreductase; pfam00070
Pyridine nucleotide-disulphide oxidoreductase; pfam07992
Pyridine nucleotide-disulphide oxidoreductase; pfam00070
Pyridine nucleotide-disulphide oxidoreductase; pfam07992
Pyridine nucleotide-disulphide oxidoreductase; pfam07992
Rab GTPase family 33 includes Rab33A and Rab33B; cd04115
Rab family protein; Provisional
Domain of unknown function (DUF4195); pfam13836
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
7 transmembrane receptor (rhodopsin family); pfam00001
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RhoGAP_ARHGAP6: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP6-like proteins. ArhGAP6 shows GAP activity towards RhoA, but not towards Cdc42 and Rac1. ArhGAP6 is often deleted in microphthalmia with linear skin...; cd04376
GTPase-activator protein for Rho-like GTPases; smart00324
Immunoglobulin domain; pfam13895
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13895
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13895
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Catalytic domain of the Protein Serine/Threonine Kinase, Mammalian Ste20-like protein kinase 4; cd06640
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Mammalian Ste20-like protein kinase 3-like Protein Serine/Threonine Kinases; cd06609
Serine/Threonine protein kinases, catalytic domain; smart00220
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
FERM adjacent (FA); pfam08736
Rap2 family GTPase consists of Rap2a, Rap2b, and Rap2c; cd04176
Rap2 family GTPase consists of Rap2a, Rap2b, and Rap2c; cd04176
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Zinc finger C-x8-C-x5-C-x3-H type (and similar); cl11592
zinc finger; smart00356
zinc finger; smart00356
zinc finger; smart00356
zinc finger; smart00356
zinc finger; smart00356
zinc finger; smart00356
zinc finger; smart00356
Sulfotransferase family; pfam03567
Sulfotransferase family; pfam03567
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cd02257
Ubiquitin carboxyl-terminal hydrolase; pfam00443
E2F/DP family winged-helix DNA-binding domain; pfam02319
Transcription factor DP; pfam08781
Glypican; pfam01153
Glypican; pfam01153
Glypican; pfam01153
Glypican; pfam01153
Glypican; pfam01153
PHD-like zinc-binding domain; pfam13771
PHD-like zinc-binding domain; pfam13771
PHD-like zinc-binding domain; pfam13771
PHD-like zinc-binding domain; pfam13771
PHD-like zinc-binding domain; pfam13771
PHD-like zinc-binding domain; pfam13771
Phosphoribosyl transferase (PRT)-type I domain; cd06223
MSP (Major sperm protein) domain; pfam00635
hypothetical protein; Provisional
S1-like; pfam14444
S1-like; pfam14444
SCAN oligomerization domain; cd07936
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc finger, C2H2 type; cl15478
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cd00198
Membrane magnesium transporter; pfam10270
sodium/hydrogen exchanger 3; TIGR00840
sodium/hydrogen exchanger 3; TIGR00840
sodium/hydrogen exchanger 3; TIGR00840
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
The first LIM domain of Four and a half LIM domains protein 1; cd09344
The second LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09424
The third LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09429
The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09348
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
The first LIM domain of Four and a half LIM domains protein 1; cd09344
The second LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09424
The third LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09429
The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09348
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
The first LIM domain of Four and a half LIM domains protein 1; cd09344
The second LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09424
The third LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09429
The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09348
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
The first LIM domain of Four and a half LIM domains protein 1; cd09344
The second LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09424
The third LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09429
The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09348
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
The first LIM domain of Four and a half LIM domains protein 1; cd09344
The second LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09424
The third LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09429
The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09348
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
The first LIM domain of Four and a half LIM domains protein 1; cd09344
The second LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09424
The third LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09429
The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09348
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
The first LIM domain of Four and a half LIM domains protein 1; cd09344
The second LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09424
The third LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09429
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
The first LIM domain of Four and a half LIM domains protein 1; cd09344
The second LIM domain of Four and a half LIM domains protein 1 (FHL1); cd09424
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cl00102
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); pfam00002
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; cl10458
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Vestigial/Tondu family; pfam07545
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cd00184
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Src Homology 3 domain of alpha-Pak Interactive eXchange factor; cd12060
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Cool (cloned out of library)/Pix (PAK-interactive exchange factor) pleckstrin homology (PH) domain; cd01225
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RBM1CTR (NUC064) family; pfam08081
7 transmembrane receptor (rhodopsin family); pfam00001
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
Domain containing Gla (gamma-carboxyglutamate) residues; smart00069
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cl15787
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
Divergent CRAL/TRIO domain; pfam13716
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
Divergent CRAL/TRIO domain; pfam13716
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
Divergent CRAL/TRIO domain; pfam13716
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
Divergent CRAL/TRIO domain; pfam13716
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
Divergent CRAL/TRIO domain; pfam13716
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
phospholipid-translocating P-type ATPase, flippase; TIGR01652
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; cl14615
phospholipid-translocating P-type ATPase, flippase; TIGR01652
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; cl14615
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
SOX transcription factor; pfam12336
Sperm protein associated with nucleus, mapped to X chromosome; pfam07458
Sperm protein associated with nucleus, mapped to X chromosome; pfam07458
Sperm protein associated with nucleus, mapped to X chromosome; pfam07458
Sperm protein associated with nucleus, mapped to X chromosome; pfam07458
Sperm protein associated with nucleus, mapped to X chromosome; pfam07458
Sperm protein associated with nucleus, mapped to X chromosome; pfam07458
MAGE family; pfam01454
MAGE family; pfam01454
MAGE family; pfam01454
MAGE family; pfam01454
MAGE family; pfam01454
Sperm protein associated with nucleus, mapped to X chromosome; pfam07458
Sperm protein associated with nucleus, mapped to X chromosome; pfam07458
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat; pfam13855
Sperm protein associated with nucleus, mapped to X chromosome; pfam07458
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Sperm protein associated with nucleus, mapped to X chromosome; pfam07458
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Agenet domain; pfam05641
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
Fragile X-related 1 protein C terminal; pfam12235
Fragile X-related 1 protein C terminal; pfam12235
Agenet domain; pfam05641
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
Fragile X-related 1 protein C terminal; pfam12235
Fragile X-related 1 protein C terminal; pfam12235
Agenet domain; pfam05641
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
Fragile X-related 1 protein C terminal; pfam12235
Agenet domain; pfam05641
KH domain; pfam00013
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
Agenet domain; pfam05641
KH domain; pfam00013
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
AF-4 proto-oncoprotein; pfam05110
AF-4 proto-oncoprotein; pfam05110
AF-4 proto-oncoprotein; pfam05110
AF-4 proto-oncoprotein; pfam05110
AF-4 proto-oncoprotein; pfam05110
AF-4 proto-oncoprotein; pfam05110
AF-4 proto-oncoprotein; pfam05110
AF-4 proto-oncoprotein; pfam05110
AF-4 proto-oncoprotein; pfam05110
AF-4 proto-oncoprotein; pfam05110
AF-4 proto-oncoprotein; pfam05110
AF-4 proto-oncoprotein; pfam05110
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; cl10460
Sulfatase; cl10460
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; cl10460
The ASCH domain adopts a beta-barrel fold similar to that of the PUA domain; smart01022
The ASCH domain adopts a beta-barrel fold similar to that of the PUA domain; smart01022
The ASCH domain adopts a beta-barrel fold similar to that of the PUA domain; smart01022
The ASCH domain adopts a beta-barrel fold similar to that of the PUA domain; smart01022
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
HSF-type DNA-binding; pfam00447
Transmembrane Fragile-X-F protein; pfam10269
Transmembrane Fragile-X-F protein; pfam10269
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
HSF-type DNA-binding; pfam00447
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
The ASCH domain adopts a beta-barrel fold similar to that of the PUA domain; smart01022
domain in glucosyltransferases, myotubularins and other putative membrane-associated proteins; smart00568
Myotubularin-related; pfam06602
Myotubularin Y_phosphatase-like; pfam13849
GRAM domain; pfam02893
Myotubularin-related; pfam06602
Myotubularin Y_phosphatase-like; pfam13849
CD99 antigen like protein 2; pfam12301
CD99 antigen like protein 2; pfam12301
CD99 antigen like protein 2; pfam12301
CD99 antigen like protein 2; pfam12301
CD99 antigen like protein 2; pfam12301
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
VMA21-like domain; pfam09446
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain; cl02449
Mitochondrial and peroxisomal fission factor Mff; pfam05644
Ion transport protein; pfam00520
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Melanoma associated antigen family N terminal; pfam12440
Melanoma associated antigen family N terminal; pfam12440
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Cation transporter family protein; TIGR00860
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
centrin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
human NSDHL (NAD(P)H steroid dehydrogenase-like protein)-like, extended (e) SDRs; cd09813
3-beta hydroxysteroid dehydrogenase/isomerase family; pfam01073
human NSDHL (NAD(P)H steroid dehydrogenase-like protein)-like, extended (e) SDRs; cd09813
3-beta hydroxysteroid dehydrogenase/isomerase family; pfam01073
LIM is a small protein-protein interaction domain, containing two zinc fingers; cd08368
LIM is a small protein-protein interaction domain, containing two zinc fingers; cd08368
LIM is a small protein-protein interaction domain, containing two zinc fingers; cd08368
LIM is a small protein-protein interaction domain, containing two zinc fingers; cd08368
LIM is a small protein-protein interaction domain, containing two zinc fingers; cd08368
LIM is a small protein-protein interaction domain, containing two zinc fingers; cd08368
LIM is a small protein-protein interaction domain, containing two zinc fingers; cd08368
LIM is a small protein-protein interaction domain, containing two zinc fingers; cd08368
Melanoma associated antigen family N terminal; pfam12440
MAGE family; pfam01454
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
DEDDh 3'-5' exonuclease domain of three prime repair exonuclease (TREX)1, TREX2, and similar proteins; cd06136
Leucine rich repeat N-terminal domain; smart00013
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Cation transporter/ATPase, N-terminus; pfam00690
Cation transport ATPase [Inorganic ion transport and metabolism]; COG0474
E1-E2 ATPase; pfam00122
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
haloacid dehalogenase-like hydrolase; pfam12710
Cation transporting ATPase, C-terminus; pfam00689
Plasma membrane calcium transporter ATPase C terminal; pfam12424
Cation transporter/ATPase, N-terminus; pfam00690
Cation transport ATPase [Inorganic ion transport and metabolism]; COG0474
E1-E2 ATPase; pfam00122
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
haloacid dehalogenase-like hydrolase; pfam12710
Cation transporting ATPase, C-terminus; pfam00689
Plasma membrane calcium transporter ATPase C terminal; pfam12424
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by...; cd01446
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Protein kinase domain; pfam00069
Na(+)- and Cl(-)-dependent creatine transporter 1; solute-binding domain; cd11509
Solute carrier families 5 and 6-like; solute binding domain; cl00456
Solute carrier families 5 and 6-like; solute binding domain; cl00456
B-cell receptor-associated protein 31-like; pfam05529
B-cell receptor-associated protein 31-like; pfam05529
B-cell receptor-associated protein 31-like; pfam05529
B-cell receptor-associated protein 31-like; pfam05529
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protei; TIGR00954
ABC transporter transmembrane region 2; pfam06472
Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome.  The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed...; cd03223
The Sema domain, a protein interacting module, of Plexin B3; cd11277
semaphorin domain; smart00630
Plexin repeat; pfam01437
Plexin repeat; cl02601
Plexin repeat; cl02601
First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present...; cd01180
Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present...; cd01179
Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; cl15674
Plexin cytoplasmic RasGAP domain; pfam08337
The Sema domain, a protein interacting module, of Plexin B3; cd11277
semaphorin domain; smart00630
Plexin repeat; pfam01437
Plexin repeat; cl02601
Plexin repeat; cl02601
First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present...; cd01180
Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present...; cd01179
Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; cl15674
Plexin cytoplasmic RasGAP domain; pfam08337
Catalytic domain of Protein Kinases; cd00180
Protein Kinases, catalytic domain; cl09925
Catalytic domain of Protein Kinases; cd00180
Protein Kinases, catalytic domain; cl09925
Catalytic domain of Protein Kinases; cd00180
Protein Kinases, catalytic domain; cl09925
isocitrate dehydrogenase, NAD-dependent, mitochondrial type; TIGR00175
tartrate dehydrogenase; Provisional
isocitrate dehydrogenase, NAD-dependent, mitochondrial type; TIGR00175
Translocon-associated protein, delta subunit precursor (TRAP-delta); pfam05404
Translocon-associated protein, delta subunit precursor (TRAP-delta); pfam05404
Translocon-associated protein, delta subunit precursor (TRAP-delta); pfam05404
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Sixth immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM) and similar proteins; cd05733
Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM) and similar proteins; cd05845
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM); cd05876
Fourth immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM); cd05867
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
C-terminal domain of Fibronectin type III; pfam13882
Sixth immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM) and similar proteins; cd05733
Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM) and similar proteins; cd05845
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM); cd05876
Fourth immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM); cd05867
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
C-terminal domain of Fibronectin type III; pfam13882
Sixth immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM) and similar proteins; cd05733
Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM) and similar proteins; cd05845
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM); cd05876
Fourth immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM); cd05867
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
C-terminal domain of Fibronectin type III; pfam13882
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Proteins; cd07656
RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when...; cl02570
GTPase-activator protein for Rho-like GTPases; smart00324
Src homology 3 domain of Slit-Robo GTPase Activating Protein 4; cd11956
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; cl12013
RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when...; cl02570
GTPase-activator protein for Rho-like GTPases; smart00324
Src homology 3 domain of Slit-Robo GTPase Activating Protein 4; cd11956
Acetyltransferases [General function prediction only]; COG0456
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; cd04301
Acetyltransferases [General function prediction only]; COG0456
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; cd04301
Acetyltransferases [General function prediction only]; COG0456
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; cd04301
AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; cd00249
N-acyl-D-glucosamine 2-epimerase [Carbohydrate transport and metabolism]
epithiospecifier protein
Kelch motif; pfam01344
Galactose oxidase, central domain; pfam13415
Galactose oxidase, central domain; pfam13415
Galactose oxidase, central domain; pfam13415
Kelch motif; pfam13854
Death domain of Interleukin 1 Receptor Associated Kinase-1; cd08794
Catalytic domain of Protein Kinases; cd00180
Death domain of Interleukin 1 Receptor Associated Kinase-1; cd08794
Catalytic domain of Protein Kinases; cd00180
Death domain of Interleukin 1 Receptor Associated Kinase-1; cd08794
Catalytic domain of Protein Kinases; cd00180
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
Predicted transmembrane and coiled-coil 2 protein; pfam10267
Predicted transmembrane and coiled-coil 2 protein; pfam10267
transketolase; Reviewed
Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; cd02012
Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; cd07033
Transketolase, C-terminal domain; pfam02780
transketolase; Reviewed
Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; cd02012
Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; cd07033
Transketolase, C-terminal domain; pfam02780
transketolase; Reviewed
Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; cd02012
Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; cd07033
Transketolase, C-terminal domain; pfam02780
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
LEM domain; pfam03020
Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; cd01433
Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; cd01433
Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; cd01433
Deoxyribonuclease 1; cd10282
Deoxyribonuclease 1; cd10282
Deoxyribonuclease 1; cd10282
Deoxyribonuclease 1; cd10282
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; cd07989
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; COG0204
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; cd07989
Vacuolar ATP synthase subunit S1 (ATP6S1); pfam05827
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
GDP dissociation inhibitor; pfam00996
XAP5, circadian clock regulator; pfam04921
The Sema domain, a protein interacting module, of Plexin A3; cd11273
semaphorin domain; smart00630
Plexin repeat; pfam01437
Plexin repeat; pfam01437
domain found in Plexins, Semaphorins and Integrins; smart00423
First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present...; cd01180
Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present...; cd01179
Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present...; cd01181
IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the...; cd00603
Plexin cytoplasmic RasGAP domain; pfam08337
Transcription factor Pcc1; pfam09341
ubiquitin-like domain of GDX; cd01807
Ubiquitin homologues; smart00213
type II restriction endonuclease, Alw26I/Eco31I/Esp3I family; TIGR02986
bile acid transporter; TIGR00841
Sodium Bile acid symporter family; pfam01758
bile acid transporter; TIGR00841
Sodium Bile acid symporter family; pfam01758
bile acid transporter; TIGR00841
Sodium Bile acid symporter family; pfam01758
glucose-6-phosphate 1-dehydrogenase; TIGR00871
Glucose-6-phosphate dehydrogenase, NAD binding domain; pfam00479
Glucose-6-phosphate dehydrogenase, C-terminal domain; pfam02781
glucose-6-phosphate 1-dehydrogenase; TIGR00871
Glucose-6-phosphate dehydrogenase, NAD binding domain; pfam00479
Glucose-6-phosphate dehydrogenase, C-terminal domain; pfam02781
NF-kappa-B essential modulator NEMO; pfam11577
polyubiquitin binding domain of NEMO and related proteins; cd09803
NF-kappa-B essential modulator NEMO; pfam11577
polyubiquitin binding domain of NEMO and related proteins; cd09803
NF-kappa-B essential modulator NEMO; pfam11577
polyubiquitin binding domain of NEMO and related proteins; cd09803
NF-kappa-B essential modulator NEMO; pfam11577
Transcription factor Pcc1; pfam09341
Transcription factor Pcc1; pfam09341
Transcription factor Pcc1; pfam09341
Transcription factor Pcc1; pfam09341
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
DKCLD (NUC011) domain; pfam08068
rRNA pseudouridine synthase, putative; TIGR00425
Pseudouridine synthase, human dyskerin like; cd02572
PUA domain; pfam01472
DKCLD (NUC011) domain; pfam08068
rRNA pseudouridine synthase, putative; TIGR00425
Pseudouridine synthase, human dyskerin like; cd02572
PUA domain; pfam01472
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain of Membrane Protein, Palmitoylated 1 (or MAGUK p55 subfamily member 1); cd12080
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain superfamily; cl17036
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain of Membrane Protein, Palmitoylated 1 (or MAGUK p55 subfamily member 1); cd12080
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain of Membrane Protein, Palmitoylated 1 (or MAGUK p55 subfamily member 1); cd12080
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Multicopper oxidase; pfam00394
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cl12042
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Histone 2A; smart00414
FUN14 family; pfam04930
Domain of unknown function (DUF1903); pfam08991
TCL1/MTCP1 family; pfam01840
Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex; cd08068
Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex; cd08068
Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex; cd08068
Prefoldin alpha subunit; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta...; cd00584
Rab GTPase family 39 (Rab39); cd04111
GST_N family, Chloride Intracellular Channel (CLIC) subfamily; composed of CLIC1-5, p64, parchorin and similar proteins. They are auto-inserting, self-assembling intracellular anion channels involved in a wide variety of functions including regulated...; cd03061
intracellular chloride channel protein; TIGR00862
C-terminal, alpha helical domain of Chloride Intracellular Channel 2; cd10298
Histone 2A; smart00414
Histone 2A; smart00414
trimethyllysine dioxygenase; TIGR02410
Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; cd00250
Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; cd00250
Sprouty protein (Spry); pfam05210
Regulated-SNARE-like domain; pfam13774
Synaptobrevin; pfam00957
Regulated-SNARE-like domain; pfam13774
Synaptobrevin; pfam00957
Regulated-SNARE-like domain; pfam13774
Synaptobrevin; pfam00957
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
40S ribosomal protein S4; Provisional
RS4NT (NUC023) domain; pfam08071
S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; cl09940
Ribosomal family S4e; pfam00900
Zfx / Zfy transcription activation region; pfam04704
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zfx / Zfy transcription activation region; pfam04704
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zfx / Zfy transcription activation region; pfam04704
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Cadherin repeat-like domain; cl15786
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Protocadherin; pfam08374
Cadherin repeat-like domain; cl15786
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Protocadherin; pfam08374
Cadherin repeat-like domain; cl15786
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Protocadherin; pfam08374
Nucleosome assembly protein (NAP); pfam00956
(NAP-L) nucleosome assembly protein -L; Provisional; cl08298
Amelogenins, cell adhesion proteins, play a role in the biomineralisation of teeth; smart00818
LisH; pfam08513
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Eukaryotic translation initiation factor eIF2A; pfam08662
LisH; pfam08513
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Eukaryotic translation initiation factor eIF2A; pfam08662
LisH; pfam08513
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Eukaryotic translation initiation factor eIF2A; pfam08662
Nucleosome assembly protein (NAP); pfam00956
(NAP-L) nucleosome assembly protein -L; Provisional; cl08298
Nucleosome assembly protein (NAP); pfam00956
(NAP-L) nucleosome assembly protein -L; Provisional; cl08298
Nucleosome assembly protein (NAP); pfam00956
(NAP-L) nucleosome assembly protein -L; Provisional; cl08298
Nucleosome assembly protein (NAP); pfam00956
(NAP-L) nucleosome assembly protein -L; Provisional; cl08298
(NAP-L) nucleosome assembly protein -L; Provisional; cl08298
Nucleosome assembly protein (NAP); pfam00956
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02659
Ubiquitin carboxyl-terminal hydrolase; pfam00443
helicase 45; Provisional
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
helicase 45; Provisional
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
FOG: TPR repeat [General function prediction only]; COG0457
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Putative binding domain; pfam13900
Thymosin beta-4 family; pfam01290
Carboxylesterase family; pfam00135
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Carboxylesterase family; pfam00135
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; COG1024
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; cd06558
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; COG1024
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; cd06558
HSF-type DNA-binding; pfam00447
HSF-type DNA-binding; pfam00447
HSF-type DNA-binding; pfam00447
HSF-type DNA-binding; pfam00447
Small domain found in the jumonji family of transcription factors; smart00545
ARID/BRIGHT DNA binding domain; cl02633
PHD-finger; pfam00628
JmjC domain, hydroxylase; pfam02373
C5HC2 zinc finger; pfam02928
PLU-1-like protein; pfam08429
PHD zinc finger; smart00249
Small domain found in the jumonji family of transcription factors; smart00545
ARID/BRIGHT DNA binding domain; pfam01388
PHD-finger; pfam00628
JmjC domain, hydroxylase; pfam02373
C5HC2 zinc finger; pfam02928
PLU-1-like protein; pfam08429
PHD zinc finger; smart00249
Small domain found in the jumonji family of transcription factors; smart00545
ARID/BRIGHT DNA binding domain; pfam01388
PHD-finger; pfam00628
JmjC domain, hydroxylase; pfam02373
C5HC2 zinc finger; pfam02928
PLU-1-like protein; pfam08429
PHD zinc finger; smart00249
S1_IF1A: Translation initiation factor IF1A, also referred to as eIF1A in eukaryotes and aIF1A in archaea, S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. IF1A is essential for translation...; cd05793
40S ribosomal protein S4; Provisional
RS4NT (NUC023) domain; pfam08071
Ribosomal family S4e; pfam00900
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RBM1CTR (NUC064) family; pfam08081
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RBM1CTR (NUC064) family; pfam08081
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RBM1CTR (NUC064) family; pfam08081
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RBM1CTR (NUC064) family; pfam08081
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RBM1CTR (NUC064) family; pfam08081
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RBM1CTR (NUC064) family; pfam08081
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; COG1024
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; cd06558
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; COG1024
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; cd06558
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; COG1024
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; cd06558
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; COG1024
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; cd06558
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Class I Histocompatibility antigen, domains alpha 1 and 2; pfam00129
Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain; cd07698
Class II histocompatibility antigen, beta domain; pfam00969
Class II major histocompatibility complex (MHC) beta chain immunoglobulin domain; cd05766
Class II histocompatibility antigen, beta domain; pfam00969
Immunoglobulin domain; cl11960
Class II histocompatibility antigen, beta domain; pfam00969
Class II major histocompatibility complex (MHC) beta chain immunoglobulin domain; cd05766
Class I Histocompatibility antigen, domains alpha 1 and 2; pfam00129
Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain; cd07698
Class II histocompatibility antigen, beta domain; pfam00969
Class II major histocompatibility complex (MHC) beta chain immunoglobulin domain; cd05766
Alpha-2-macroglobulin MG1 domain; pfam11974
MG2 domain; pfam01835
Alpha-2-macroglobulin family N-terminal region; pfam07703
Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to...; cd00017
Alpha-2-macroglobulin family; pfam00207
Proteins similar to C3, C4 and C5 of vertebrate complement.  The vertebrate complement system, comprised of a large number of distinct plasma proteins, is an effector of both the acquired and innate immune systems. The point of convergence of the...; cd02896
A-macroglobulin complement component; pfam07678
A-macroglobulin receptor; pfam07677
NTR/C345C domain, complement C4 subfamily; The NTR domain found in complement C4 is also known as the C345C domain because it occurs at the C-terminus of complement C3, C4 and C5. Complement C4 is a key player in the activation of the component classical...; cd03584
Regulated-SNARE-like domain; pfam13774
Synaptobrevin; pfam00957
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Secretoglobins are relatively small, secreted, disulphide-bridged dimeric proteins with encoding genes sharing substantial sequence similarity. Their family subunits may be grouped into five subfamilies, A-E. Uteroglobin (subfamily A), which is identical...; cd00633
Inward rectifier potassium channel N-terminal; pfam08466
Inward rectifier potassium channel; pfam01007
APOBEC-like N-terminal domain; pfam08210
Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; cd01283
APOBEC-like C-terminal domain; pfam05240
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Cation transporter family protein; TIGR00860
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Ca2+ insensitive EF hand; pfam08726
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Ca2+ insensitive EF hand; pfam08726
Catalytic domain of the Protein Serine/Threonine Kinase, Never In Mitosis gene A-related kinase 3; cd08219
Serine/Threonine protein kinases, catalytic domain; smart00220
7 transmembrane receptor (rhodopsin family); pfam00001
Interferon-induced 6-16 family; pfam06140
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Eukaryotic core primase: Large subunit, PriL; cd07322
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Glycolipid transfer protein (GLTP); pfam08718
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cl00074
Predicted exporters of the RND superfamily [General function prediction only]
Predicted exporters of the RND superfamily [General function prediction only]
Tissue factor; pfam01108
Tissue factor; pfam01108
Tissue factor; pfam01108
Mitochondrial fission regulator; pfam05308
Mitochondrial fission regulator; pfam05308
Mitochondrial fission regulator; pfam05308
Mitochondrial fission regulator; pfam05308
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Domain present in hormone receptors; smart00008
Domain of unknown function (DUF3497); pfam12003
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Ornithine Decarboxylase; cd00622
protein argonaute; Provisional
Domain of unknown function (DUF1785); pfam08699
PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; cd02846
Piwi_ago-like: PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of...; cd04657
protein argonaute; Provisional
Domain of unknown function (DUF1785); pfam08699
PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; cd02846
Piwi_ago-like: PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of...; cd04657
protein argonaute; Provisional
Domain of unknown function (DUF1785); pfam08699
PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; cd02846
Piwi_ago-like: PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of...; cd04657
PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; cd02846
Piwi_ago-like: PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of...; cd04657
Utp11 protein; pfam03998
Myc amino-terminal region; pfam01056
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Myc amino-terminal region; pfam01056
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Myc amino-terminal region; pfam01056
SCAN oligomerization domain; cl02605
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cl02605
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam13640
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam13640
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam13640
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Insulinase (Peptidase family M16); pfam00675
Secreted/periplasmic Zn-dependent peptidases, insulinase-like [Posttranslational modification, protein turnover, chaperones]; COG1025
Peptidase M16 inactive domain; pfam05193
Peptidase M16 inactive domain; pfam05193
Insulinase (Peptidase family M16); pfam00675
Secreted/periplasmic Zn-dependent peptidases, insulinase-like [Posttranslational modification, protein turnover, chaperones]; COG1025
Peptidase M16 inactive domain; pfam05193
Peptidase M16 inactive domain; pfam05193
Secreted/periplasmic Zn-dependent peptidases, insulinase-like [Posttranslational modification, protein turnover, chaperones]; COG1025
Insulinase (Peptidase family M16); pfam00675
Peptidase M16 inactive domain; pfam05193
Peptidase M16 inactive domain; pfam05193
Nucleoporin protein Ndc1-Nup; pfam09531
Nucleoporin protein Ndc1-Nup; pfam09531
Nucleoporin protein Ndc1-Nup; pfam09531
Nucleoporin protein Ndc1-Nup; pfam09531
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
L27_2; pfam09045
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Uncharacterized conserved protein (DUF2217); pfam10265
Uncharacterized conserved protein (DUF2217); pfam10265
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Domain of unknown function (DUF3497); pfam12003
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); pfam00002
Galactose binding lectin domain; pfam02140
Olfactomedin-like domain; pfam02191
Domain present in hormone receptors; smart00008
Domain of unknown function (DUF3497); pfam12003
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
Latrophilin Cytoplasmic C-terminal region; pfam02354
hypothetical protein; Provisional
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; cd00609
hypothetical protein; Provisional
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; cd00609
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Major Facilitator Superfamily; pfam07690
cyclophilin_ABH_like: Cyclophilin  A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which...; cd01926
Protein of unknown function (DUF3735); pfam12537
Abscisic acid G-protein coupled receptor; pfam12430
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
DHH family; pfam01368
Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion]; COG1227
DHHA2 domain; pfam02833
YjeF-related protein N-terminus; cl00318
Tumour suppressor, Mitostatin; pfam13868
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Second immunoglobulin (Ig) domain of nectin-3 (also known as poliovirus receptor related protein 3), nectin-4 (poliovirus receptor related protein 4) and similar proteins; cd07704
Immunoglobulin domain; cd00096
membrane-attack complex / perforin; smart00457
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; cd00761
Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; cd06532
membrane-attack complex / perforin; smart00457
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Rab family protein; Provisional
Rab GTPase families 18 (Rab18) and 32 (Rab32); cd04107
Rab family protein; Provisional
Rab GTPase families 18 (Rab18) and 32 (Rab32); cd04107
Rab family protein; Provisional
Rab GTPase families 18 (Rab18) and 32 (Rab32); cd04107
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin V-set domain; pfam07686
Pecanex protein (C-terminus); pfam05041
Endoplasmic Reticulum Oxidoreductin 1 (ERO1); pfam04137
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Uncharacterized conserved protein (DUF2305); pfam10230
Alpha/beta hydrolase family; pfam12697
Hormone receptor domain; cl02422
Domain of unknown function (DUF3497); pfam12003
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
Hormone receptor domain; cl02422
Domain of unknown function (DUF3497); pfam12003
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
Hormone receptor domain; cl02422
Domain of unknown function (DUF3497); pfam12003
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
EamA-like transporter family; pfam00892
G-patch domain; pfam01585
Domain of unknown function (DUF4187); pfam13821
hnRNP-L/PTB/hephaestus splicing factor family; TIGR01649
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
hnRNP-L/PTB/hephaestus splicing factor family; TIGR01649
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
The ARF-like 2 binding protein BART; pfam11527
Pleckstrin homology-like domain; cl00273
Component of IIS longevity pathway SMK-1; pfam04802
Pleckstrin homology-like domain; cl00273
Component of IIS longevity pathway SMK-1; pfam04802
Uncharacterized conserved protein (DUF2363); pfam10155
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
FHA Ki67 binding domain of hNIFK; pfam12196
WTX protein; pfam09422
WTX protein; pfam09422
WTX protein; pfam09422
WTX protein; pfam09422
WTX protein; pfam09422
WTX protein; pfam09422
WTX protein; pfam09422
WTX protein; pfam09422
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch motif; pfam13964
Kelch motif; pfam01344
Kelch motif; pfam13964
Kelch motif; pfam01344
Predicted integral membrane metal-binding protein [General function prediction only]
Predicted integral membrane metal-binding protein (DUF2296); pfam10058
Shugoshin N-terminal coiled-coil region; pfam07558
Shugoshin N-terminal coiled-coil region; pfam07558
Shugoshin N-terminal coiled-coil region; pfam07558
Cell differentiation family, Rcd1-like; pfam04078
FOG: WD40 repeat [General function prediction only]
WD40 repeats; smart00320
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
7 transmembrane receptor (rhodopsin family); pfam00001
MOC1-like protein; Provisional
Hydrogenase expression/synthesis hypA family; pfam01155
FYVE zinc finger; pfam01363
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Rabenosyn Rab binding domain; pfam11464
Rabenosyn Rab binding domain; pfam11464
pp-GalNAc-T initiates the formation of mucin-type O-linked glycans; cd02510
Ricin-type beta-trefoil lectin domain; pfam00652
Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; cd00161
Shugoshin N-terminal coiled-coil region; pfam07558
Shugoshin C terminus; pfam07557
Shugoshin N-terminal coiled-coil region; pfam07558
Shugoshin C terminus; pfam07557
Shugoshin N-terminal coiled-coil region; pfam07558
Shugoshin N-terminal coiled-coil region; pfam07558
Shugoshin C terminus; pfam07557
Shugoshin N-terminal coiled-coil region; pfam07558
Shugoshin C terminus; pfam07557
Shugoshin N-terminal coiled-coil region; pfam07558
Shugoshin C terminus; pfam07557
Shugoshin N-terminal coiled-coil region; pfam07558
Shugoshin C terminus; pfam07557
Shugoshin N-terminal coiled-coil region; pfam07558
Shugoshin C terminus; pfam07557
Shugoshin N-terminal coiled-coil region; pfam07558
Shugoshin C terminus; pfam07557
Shugoshin N-terminal coiled-coil region; pfam07558
Shugoshin C terminus; pfam07557
Shugoshin N-terminal coiled-coil region; pfam07558
Shugoshin C terminus; pfam07557
Shugoshin N-terminal coiled-coil region; pfam07558
Shugoshin C terminus; pfam07557
Shugoshin N-terminal coiled-coil region; pfam07558
Shugoshin C terminus; pfam07557
BTB/POZ domain; pfam00651
BTB And C-terminal Kelch; pfam07707
Kelch domain; smart00612
Kelch domain; smart00612
Kelch motif; pfam01344
G protein-coupled chemokine receptor-like protein; Provisional
SCAN oligomerization domain; cd07936
KRAB (Kruppel-associated box) domain -A box; cd07765
SCAN oligomerization domain; cd07936
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; cd00209
Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; cd00209
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig) domain of nectin-3 (also known as poliovirus receptor related protein 3) and similar proteins; cd05887
Second immunoglobulin (Ig) domain of nectin-3 (also known as poliovirus receptor related protein 3), nectin-4 (poliovirus receptor related protein 4) and similar proteins; cd07704
Immunoglobulin; smart00409
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig) domain of nectin-3 (also known as poliovirus receptor related protein 3) and similar proteins; cd05887
Second immunoglobulin (Ig) domain of nectin-3 (also known as poliovirus receptor related protein 3), nectin-4 (poliovirus receptor related protein 4) and similar proteins; cd07704
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig) domain of nectin-3 (also known as poliovirus receptor related protein 3) and similar proteins; cd05887
Second immunoglobulin (Ig) domain of nectin-3 (also known as poliovirus receptor related protein 3), nectin-4 (poliovirus receptor related protein 4) and similar proteins; cd07704
Immunoglobulin; smart00409
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 repeats; smart00320
Protein of unknown function (DUF1168); pfam06658
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 repeats; smart00320
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
queuine tRNA-ribosyltransferase; Provisional; cl00409
Queuine tRNA-ribosyltransferase; pfam01702
queuine tRNA-ribosyltransferase; Provisional; cl00409
Queuine tRNA-ribosyltransferase; pfam01702
queuine tRNA-ribosyltransferase; Provisional; cl00409
Queuine tRNA-ribosyltransferase; pfam01702
queuine tRNA-ribosyltransferase; Provisional; cl00409
Queuine tRNA-ribosyltransferase; pfam01702
Protein tyrosine phosphatase-like protein, PTPLA; pfam04387
Domain of unknown function (DUF4200); pfam13863
Uncharacterized ACR, COG2135; pfam02586
Uncharacterized ACR, COG2135; pfam02586
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; cd07061
Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; cd07061
Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; cd07061
Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; cd07061
Transmembrane proteins 14C; pfam03647
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam13640
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam13640
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Transferrin; pfam00405
Transferrin; smart00094
Transferrin; cl02460
domain involved in Ras-like GTPase signaling; smart00593
Domain of unknown function (DUF4206); pfam13901
domain involved in Ras-like GTPase signaling; smart00593
Domain of unknown function (DUF4206); pfam13901
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Hormone receptor domain; cl02422
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
Protein of unknown function (DUF2615); pfam11027
Galactose binding lectin domain; pfam02140
Olfactomedin-like domains; smart00284
Domain present in hormone receptors; smart00008
Domain of unknown function (DUF3497); pfam12003
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
Latrophilin Cytoplasmic C-terminal region; pfam02354
Mif2/CENP-C like; pfam11699
Chemokine_CXC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members...; cd00273
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; cd07991
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; cd07991
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; cd07991
4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; COG0160
Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; cd00610
4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; COG0160
Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; cd00610
acetylornithine transaminase
Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; cd00610
Protein of unknown function, DUF607; pfam04678
Protein of unknown function (DUF2439); pfam10382
GRF zinc finger; pfam06839
AAA domain; pfam13086
AAA domain; pfam13087
Uncharacterized conserved protein (DUF2048); pfam09752
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Enhancer of polycomb-like; pfam10513
PHD-finger; pfam00628
PHD-zinc-finger like domain; pfam13832
PHD zinc finger; smart00249
Enhancer of polycomb-like; pfam10513
PHD-finger; pfam13831
PHD-zinc-finger like domain; pfam13832
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cl15348
C-terminal deadenylase domain of nocturnin and related domains; cd09096
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Uncharacterized conserved protein (DUF2228); pfam10228
Eukaryotic and archaeal DNA primase small subunit; pfam01896
Herpesviridae UL52/UL70 DNA primase; pfam03121
CENP-A nucleosome associated complex (NAC) subunit; pfam13097
KIAA1430 homologue; pfam13879
OTU-like cysteine protease; cl14910
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
Protein of unknown function (DUF974); pfam06159
Protein of unknown function (DUF974); pfam06159
Protein of unknown function (DUF974); pfam06159
Protein of unknown function (DUF974); pfam06159
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Calx-beta domain; cl02522
Calx-beta domain; cl02522
Calx-beta domain; cl02522
Calx-beta domain; cl02522
Calx-beta domain; cl02522
Calx-beta domain; cl02522
Concanavalin A-like lectin/glucanases superfamily; pfam13385
Calx-beta domain; cl02522
Calx-beta domain; pfam03160
Calx-beta domain; cl02522
Calx-beta domain; cl02522
Calx-beta domain; cl02522
Calx-beta domain; cl02522
Calx-beta domain; cl02522
Calx-beta domain; cl02522
Calx-beta domain; cl02522
EPTP domain; pfam03736
Calx-beta domain; cl02522
Calx-beta domain; cl02522
Calx-beta domain; cl02522
Domains in Na-Ca exchangers and integrin-beta4; smart00237
Calx-beta domain; cl02522
Calx-beta domain; cl02522
Calx-beta domain; cl02522
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Peptidase family M1; pfam01433
Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ); cd09601
Domain of unknown function (DUF3358); pfam11838
Enhancer of polycomb-like; pfam10513
PHD-finger; pfam13831
PHD-zinc-finger like domain; pfam13832
Sterol desaturase [Lipid metabolism]; COG3000
Fatty acid hydroxylase superfamily; pfam04116
4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; COG0160
Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; cd00610
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Protein of unknown function (DUF1640); pfam07798
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
SCAN oligomerization domain; cd07936
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
Integrase core domain; pfam00665
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RAI1 like PD-(D/E)XK nuclease; pfam08652
G-patch domain; pfam01585
FtsJ-like methyltransferase; pfam01728
Adenylation domain of proteins similar to ATP-dependent polynucleotide ligases; cl12015
Nucleoside 2-deoxyribosyltransferase; pfam05014
Nucleoside 2-deoxyribosyltransferase; pfam05014
SEA domain; pfam01390
Immunoglobulin domain; cd00096
Immunoglobulin like; smart00410
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
SEA domain; pfam01390
Immunoglobulin domain; cd00096
Immunoglobulin like; smart00410
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
SEA domain; pfam01390
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
SEA domain; cl02507
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Domain present in hormone receptors; smart00008
Domain of unknown function (DUF3497); pfam12003
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
Protein of unknown function (DUF1674); pfam07896
chromosome segregation protein SMC, common bacterial type; TIGR02168
Domain of unknown function (DUF3508); pfam12018
adenylate kinases; TIGR01351
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; cd01428
AAA domain; pfam13207
Ribosomal protein L24e/L24 is a ribosomal protein found in eukaryotes (L24) and in archaea (L24e, distinct from archaeal L24). L24e/L24 is located on the surface of the large subunit, adjacent to proteins L14 and L3, and near the translation factor...; cl00909
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; cd01428
Adenylate kinase and related kinases [Nucleotide transport and metabolism]; COG0563
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; cd01428
adenylate kinases; TIGR01351
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; cd01428
AAA domain; pfam13207
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Major Facilitator Superfamily; pfam07690
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Transport protein particle (TRAPP) component; pfam04051
Rab-GTPase-TBC domain; cl02495
Mitochondrial fission regulator; pfam05308
Mitochondrial fission regulator; pfam05308
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor...; cd00171
Domain of unknown function (DUF1981); pfam09324
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cl00102
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cl00102
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cl00102
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cl00102
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
Protein of unknown function DUF89; pfam01937
Ubiquitin domain of AT-6, first repeat; cd01782
Ubiquitin domain of AT-6, second repeat; cd01781
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
DIL domain; pfam01843
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Ubiquitin domain of AT-6, first repeat; cd01782
Ubiquitin domain of AT-6, second repeat; cd01781
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
DIL domain; pfam01843
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Domain of unknown function (DUF4209); pfam13910
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
23S rRNA methylase [Translation, ribosomal structure and biogenesis]; COG0293
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
haloacid dehalogenase superfamily, subfamily IE hydrolase, TIGR01544
Haloacid Dehalogenase-like Hydrolases; cl11391
haloacid dehalogenase superfamily, subfamily IE hydrolase, TIGR01544
Haloacid Dehalogenase-like Hydrolases; cl11391
haloacid dehalogenase superfamily, subfamily IE hydrolase, TIGR01544
Haloacid Dehalogenase-like Hydrolases; cl11391
haloacid dehalogenase superfamily, subfamily IE hydrolase, TIGR01544
Haloacid Dehalogenase-like Hydrolases; cl11391
Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; COG1804
CoA-transferase family III; pfam02515
Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; COG1804
CoA-transferase family III; pfam02515
Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; COG1804
CoA-transferase family III; pfam02515
Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; COG1804
CoA-transferase family III; pfam02515
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam13540
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam13540
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam13540
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Protein of unknown function (DUF2678); pfam10856
mTERF; pfam02536
Protein of unknown function N-terminal domain (DUF2450); pfam10475
Protein of unknown function C-terminus (DUF2451); pfam10474
Protein of unknown function N-terminal domain (DUF2450); pfam10475
Protein of unknown function N-terminal domain (DUF2450); pfam10475
Protein of unknown function C-terminus (DUF2451); pfam10474
Complex1_LYR-like; pfam13233
SCAN oligomerization domain; cd07936
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
GTPase SAR1 and related small G proteins [General function prediction only]
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
EMI domain; pfam07546
PHD-finger; pfam00628
Proteins containing SET domain [General function prediction only]
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
PHD-finger; pfam00628
Proteins containing SET domain [General function prediction only]
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Complex1_LYR-like; pfam13233
PHD zinc finger; smart00249
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; cl15814
Peptidase M60-like family; pfam13402
Peptidase M60-like family; pfam13402
Putative binding domain; pfam13900
Peptidase M60-like family; pfam13402
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
Peptidase M60-like family; pfam13402
Peptidase M60-like family; pfam13402
Peptidase M60-like family; pfam13402
Copper amine oxidase, N2 domain; pfam02727
Copper amine oxidase, N3 domain; pfam02728
Copper amine oxidase, enzyme domain; pfam01179
PHD-like zinc-binding domain; pfam13771
PHD-finger; pfam00628
PHD-finger; pfam00628
PHD-finger; pfam00628
PHD-finger; pfam00628
PHD-finger; pfam00628
PHD-finger; pfam00628
High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I...; cd00084
PHD-like zinc-binding domain; pfam13771
PHD zinc finger; smart00249
F/Y-rich N-terminus; pfam05964
F/Y rich C-terminus; pfam05965
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Cysteine-rich motif following a subset of SET domains; smart00508
EF-hand domain pair; pfam13833
centrin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13833
Villin headpiece domain; pfam02209
Villin headpiece domain; pfam02209
Villin headpiece domain; pfam02209
Villin headpiece domain; pfam02209
Villin headpiece domain; pfam02209
Villin headpiece domain; pfam02209
S1-like; pfam14444
DBC1; pfam14443
Protein of unknown function (DUF1183); pfam06682
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Hormone receptor domain; pfam02793
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both...; cd03390
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both...; cd03390
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both...; cd03390
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; cd07991
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429