7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
SAM domain of Samd7,11 subfamily of Polycomb group; cd09579
Sterile alpha motif; smart00454
Uncharacterized conserved protein [Function unknown]
Noc2p family; pfam03715
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch domain; smart00612
Kelch domain; smart00612
Kelch domain; smart00612
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
Pleckstrin homology-like domain; cl00273
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Hairy Orange; pfam07527
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Hairy Orange; pfam07527
ISG15 ubiquitin-like protein, first repeat of 2; cd01792
Ubiquitin homologues; smart00213
Ubiquitin-like proteins; cl00155
Ubiquitin family; pfam00240
Agrin NtA domain; pfam03146
Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cd00104
Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cd00104
Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cd00104
Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cd00104
Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cd00104
factor I membrane attack complex; smart00057
Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cd00104
Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cd00104
Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cd00104
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cd00104
Domain found in sea urchin sperm protein, enterokinase, agrin; smart00200
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Ring finger domain; pfam13639
ATP-grasp domain; cl03087
ATP-grasp domain; cl03087
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Galactosyltransferase; cl09537
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
sodium channel transporter; TIGR00859
The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with Coiled-coil, ANK repeat and PH domain containing protein 3; cd07637
Centaurin Pleckstrin homology (PH) domain; cd01250
Putative GTPase activating protein for Arf; pfam01412
GTPase-activating protein that regulates ARFs (ADP-ribosylation factors), involved in ARF-mediated vesicular transport [Intracellular trafficking and secretion]
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
tRNA pseudouridine synthase A; Validated; PRK00021
Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; cd02570
Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; COG1236
Beta-Casp domain; smart01027
RNA-metabolising metallo-beta-lactamase; pfam07521
Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; COG1236
Metallo-beta-lactamase superfamily; smart00849
Beta-Casp domain; smart01027
RNA-metabolising metallo-beta-lactamase; pfam07521
Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; COG1236
Beta-Casp domain; smart01027
RNA-metabolising metallo-beta-lactamase; pfam07521
Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; COG1236
Metallo-beta-lactamase superfamily; smart00849
Beta-Casp domain; smart01027
RNA-metabolising metallo-beta-lactamase; pfam07521
Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; COG1236
Metallo-beta-lactamase superfamily; smart00849
Beta-Casp domain; smart01027
RNA-metabolising metallo-beta-lactamase; pfam07521
Glycolipid transfer protein (GLTP); pfam08718
Ligand-binding domain of the T1R taste receptor; cd06363
Receptor family ligand binding region; pfam01094
Nine Cysteines Domain of family 3 GPCR; pfam07562
7 transmembrane sweet-taste receptor of 3 GCPR; pfam00003
Domain present in Dishevelled and axin; smart00021
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins.  Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway...; cd04438
Segment polarity protein dishevelled (Dsh) C terminal; pfam12316
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Mitochondrial domain of unknown function (DUF1713); pfam08213
Mitochondrial domain of unknown function (DUF1713); pfam08213
Mitochondrial domain of unknown function (DUF1713); pfam08213
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Ribosomal protein L20; cd07026
ribosomal protein L20; CHL00068
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
von Willebrand factor (vWF) type A domain; equivalent to the I-domain of integrins.  This domain has a variety of functions including: intermolecular adhesion, cell migration, signalling, transcription, and DNA repair. In integrins these domains form...; cd01472
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; COG0464
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Domain of unknown function (DUF3523); pfam12037
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
Domain of unknown function (DUF3523); pfam12037
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
Domain of unknown function (DUF3523); pfam12037
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
Domain of unknown function (DUF3523); pfam12037
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
Ssu72-like protein; pfam04722
Mib_herc2; pfam06701
Zinc finger, ZZ type. Zinc finger present in Drosophila Mind bomb (D-mib) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Mind bomb is an E3 ubiqitin ligase that has...; cd02339
Mib_herc2; pfam06701
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13857
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Zinc finger, C3HC4 type (RING finger); pfam13920
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Mib_herc2; pfam06701
Zinc finger, ZZ type. Zinc finger present in Drosophila Mind bomb (D-mib) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Mind bomb is an E3 ubiqitin ligase that has...; cd02339
Mib_herc2; pfam06701
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13857
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Zinc finger, C3HC4 type (RING finger); pfam13920
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Mib_herc2; pfam06701
Zinc finger, ZZ type. Zinc finger present in Drosophila Mind bomb (D-mib) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Mind bomb is an E3 ubiqitin ligase that has...; cd02339
Mib_herc2; pfam06701
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Zinc finger, C3HC4 type (RING finger); pfam13920
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Mib_herc2; pfam06701
Zinc finger, ZZ type. Zinc finger present in Drosophila Mind bomb (D-mib) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Mind bomb is an E3 ubiqitin ligase that has...; cd02339
Mib_herc2; pfam06701
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13857
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Zinc finger, C3HC4 type (RING finger); pfam13920
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Mib_herc2; pfam06701
Zinc finger, ZZ type. Zinc finger present in Drosophila Mind bomb (D-mib) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Mind bomb is an E3 ubiqitin ligase that has...; cd02339
Mib_herc2; pfam06701
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate...; cd04278
ShK toxin domain; smart00254
Immunoglobulin C-2 Type; smart00408
Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1; cd07843
cyclin-dependent kinase A; Provisional
Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1; cd07843
cyclin-dependent kinase A; Provisional
Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1; cd07843
cyclin-dependent kinase A; Provisional
Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1; cd07843
cyclin-dependent kinase A; Provisional
Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1; cd07843
cyclin-dependent kinase A; Provisional
Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1; cd07843
cyclin-dependent kinase A; Provisional
Tpt phosphate/phosphoenolpyruvate translocator; TIGR00817
Triose-phosphate Transporter family; pfam03151
Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1; cd07843
cyclin-dependent kinase A; Provisional
Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 2-like 1; cd07843
cyclin-dependent kinase A; Provisional
Tpt phosphate/phosphoenolpyruvate translocator; TIGR00817
Tpt phosphate/phosphoenolpyruvate translocator; TIGR00817
NAD kinase [Coenzyme metabolism]; COG0061
inorganic polyphosphate/ATP-NAD kinase; Provisional; PRK02231
NAD kinase [Coenzyme metabolism]; COG0061
inorganic polyphosphate/ATP-NAD kinase; Provisional; PRK02231
NAD kinase [Coenzyme metabolism]; COG0061
NAD kinase [Coenzyme metabolism]; COG0061
inorganic polyphosphate/ATP-NAD kinase; Provisional; PRK02231
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Cation transporter family protein; TIGR00860
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
PB1 domain is an essential modular domain of the atypical protein kinase C (aPKC) which in complex with Par6 and Par3  proteins is crucial for establishment of apical-basal polarity of animal cells. PB1 domain is a modular domain mediating specific...; cd06404
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, Atypical Protein Kinase C; cd05588
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, Atypical Protein Kinase C; cd05588
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, Atypical Protein Kinase C; cd05588
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, Atypical Protein Kinase C; cd05588
SKI/SNO/DAC family; pfam02437
c-SKI Smad4 binding domain; pfam08782
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; cl12013
Uncharacterized protein conserved in bacteria [Function unknown]
MORN repeat; pfam02493
MORN repeat; cl14787
MORN repeat; cl14787
Rer1 family; pfam03248
Pex2 / Pex12 amino terminal region; pfam04757
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Pex2 / Pex12 amino terminal region; pfam04757
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Phospholipase C (PLC) pleckstrin homology (PH) domain; cd01248
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Phosphoinositide-specific phospholipase C, efhand-like; pfam09279
Catalytic domain of metazoan phosphoinositide-specific phospholipase C-eta; cd08594
Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; cl14615
C2 domain present in Phosphoinositide-specific phospholipases C (PLC); cd00275
pantothenate kinase
Fumble; pfam03630
Protein of unknown function DUF89; pfam01937
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Orange domain; smart00511
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these...; cd02970
AhpC/TSA antioxidant enzyme; pfam13911
Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these...; cd02970
AhpC/TSA antioxidant enzyme; pfam13911
Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these...; cd02970
AhpC/TSA antioxidant enzyme; pfam13911
Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these...; cd02970
AhpC/TSA antioxidant enzyme; pfam13911
Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these...; cd02970
AhpC/TSA antioxidant enzyme; pfam13911
Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these...; cd02970
AhpC/TSA antioxidant enzyme; pfam13911
Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; COG3590
Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; cd08662
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Actin; pfam00022
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc finger, C2H2 type; cl15478
Zinc finger, C2H2 type; cl15478
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc finger, C2H2 type; cl15478
Zinc finger, C2H2 type; cl15478
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Ephexin Pleckstrin homology (PH) domain; cd01221
Src homology 3 domain of the Rho guanine nucleotide exchange factors ARHGEF16 and ARHGEF26; cd11938
EMI domain; pfam07546
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Complement Clr-like EGF-like; pfam12662
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Complement Clr-like EGF-like; pfam12662
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Inositol phosphatase; pfam12456
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
P53 DNA-binding domain; cd08367
P53 tetramerisation motif; pfam07710
SAM domain (Sterile alpha motif); pfam07647
SAM domain of tumor-p73 proteins; cd09571
P53 DNA-binding domain; cd08367
P53 tetramerisation motif; pfam07710
SAM (Sterile alpha motif ); cl15755
P53 DNA-binding domain; cd08367
P53 tetramerisation motif; pfam07710
SAM (Sterile alpha motif ); cl15755
SAM domain (Sterile alpha motif); pfam07647
P53 DNA-binding domain; cd08367
P53 tetramerisation motif; pfam07710
P53 DNA-binding domain; cd08367
P53 tetramerisation motif; pfam07710
P53 DNA-binding domain; cd08367
P53 tetramerisation motif; pfam07710
P53 DNA-binding domain; cd08367
P53 tetramerisation motif; pfam07710
SAM domain (Sterile alpha motif); pfam07647
SAM domain of tumor-p73 proteins; cd09571
P53 DNA-binding domain; cd08367
P53 tetramerisation motif; pfam07710
SAM (Sterile alpha motif ); cl15755
P53 DNA-binding domain; cd08367
P53 tetramerisation motif; pfam07710
SAM (Sterile alpha motif ); cl15755
SAM domain (Sterile alpha motif); pfam07647
P53 DNA-binding domain; cd08367
P53 tetramerisation motif; pfam07710
P53 DNA-binding domain; cd08367
P53 tetramerisation motif; pfam07710
P53 DNA-binding domain; cd08367
P53 tetramerisation motif; pfam07710
P53 DNA-binding domain; cd08367
P53 tetramerisation motif; pfam07710
SAM domain (Sterile alpha motif); pfam07647
SAM domain of tumor-p73 proteins; cd09571
chromosome segregation protein SMC, common bacterial type; TIGR02168
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine Rich repeats (2 copies); pfam12799
B3/4 domain; smart00873
CIDE_N domain of CAD nuclease. The CIDE_N (cell death-inducing DFF45-like effector, N-terminal) domain is found at the N-terminus of CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are...; cd06535
DNA fragmentation factor 40 kDa; pfam09230
Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; COG0667
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; COG0667
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; COG0667
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; COG0667
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; COG0667
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Aldo/keto reductase family; pfam00248
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
CHDNT (NUC034) domain; pfam08073
PHD-finger; pfam00628
PHD-finger; pfam00628
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; COG0513
Domain of Unknown Function (DUF1087); pfam06465
Domain of Unknown Function (DUF1086); pfam06461
CHDCT2 (NUC038) domain; pfam08074
Ribosomal L22e protein family; pfam01776
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
B-Box C-terminal domain; smart00502
Isoprenylcysteine carboxyl methyltransferase (ICMT) family; pfam04140
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
7 transmembrane receptor (rhodopsin family); pfam00001
Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; cd03442
Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; cd03442
Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; cd03442
Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; cd03442
Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; cd03442
Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; cd03442
Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; cd03442
Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; cd03442
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Orange domain; smart00511
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Death domain of Tumor Necrosis Factor Receptor superfamily 25; cd08815
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cl12111
Death domain of Tumor Necrosis Factor Receptor superfamily 25; cd08815
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Death domain of Tumor Necrosis Factor Receptor superfamily 25; cd08815
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Death domain of Tumor Necrosis Factor Receptor superfamily 25; cd08815
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Death domain of Tumor Necrosis Factor Receptor superfamily 25; cd08815
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cl12111
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology (PH) domain; cd00821
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology (PH) domain; cd00821
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology (PH) domain; cd00821
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology (PH) domain; cd00821
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology (PH) domain; cd00821
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology (PH) domain; cd00821
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology (PH) domain; cd00821
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology (PH) domain; cd00821
Molybdopterin guanine dinucleotide synthesis protein B; pfam03205
Pre-mRNA cleavage complex II protein Clp1; pfam06807
Ligand-binding domain of the T1R taste receptor; cd06363
Receptor family ligand binding region; pfam01094
Nine Cysteines Domain of family 3 GPCR; pfam07562
7 transmembrane sweet-taste receptor of 3 GCPR; pfam00003
Type 1 periplasmic binding fold superfamily; cl10011
Type 1 periplasmic binding fold superfamily; cl10011
Nine Cysteines Domain of family 3 GPCR; pfam07562
7 transmembrane sweet-taste receptor of 3 GCPR; pfam00003
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Galactose oxidase, central domain; cl02701
Kelch motif; pfam01344
Kelch motif; pfam01344
Kelch motif; pfam01344
PHD-finger; pfam00628
THAP domain; pfam05485
THAP domain; pfam05485
THAP domain; pfam05485
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
Domain of unknown function (DUF3395); pfam11875
CG-1 domains are highly conserved domains of about 130 amino-acid residues; smart01076
IPT/TIG domain; pfam01833
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13637
Synaptobrevin; pfam00957
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
Period protein 2/3C-terminal region; pfam12114
Urotensin II; pfam02083
Urotensin II; pfam02083
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
DJ-1 family protein; TIGR01383
Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; cd03135
DJ-1 family protein; TIGR01383
Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; cd03135
GTPase binding; pfam09027
EGFR receptor inhibitor Mig-6; pfam11555
GPH family sucrose/H+ symporter; TIGR01301
GPH family sucrose/H+ symporter; TIGR01301
BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH...; cd04709
ELM2 domain; pfam01448
Myb-Like Dna-Binding Domain of MTA3 and related proteins; cd11661
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C; cd00202
Atrophin-1 family; pfam03154
BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH...; cd04709
ELM2 domain; pfam01448
Myb-Like Dna-Binding Domain of MTA3 and related proteins; cd11661
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C; cd00202
Atrophin-1 family; pfam03154
Atrophin-1 family; pfam03154
enolase
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; cd03313
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; cd03313
Enolase, C-terminal TIM barrel domain; pfam00113
Carbonic anhydrase alpha, isozyme VI. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, followed...; cd03125
Carbonic anhydrase alpha, isozyme VI. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, followed...; cd03125
Carbonic anhydrase alpha, isozyme VI. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, followed...; cd03125
Carbonic anhydrase alpha (vertebrate-like) group. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; cl00012
Sugar (and other) transporter; pfam00083
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Sugar (and other) transporter; pfam00083
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Sugar (and other) transporter; pfam00083
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
7 transmembrane receptor (Secretin family); cl12142
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; COG0364
Glucose-6-phosphate dehydrogenase, NAD binding domain; pfam00479
Glucose-6-phosphate dehydrogenase, C-terminal domain; pfam02781
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; cd01400
Domain in SPla and the RYanodine Receptor; smart00449
SOCS (suppressors of cytokine signaling) box of SSB1 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB1 has been shown to bind to MET, the receptor protein-tyrosine kinase for...; cd03744
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Uncharacterized conserved protein (DUF2349); pfam09779
Protein of unknown function C-terminus (DUF2448); pfam10476
Uncharacterized conserved protein (DUF2349); pfam09779
Protein of unknown function C-terminus (DUF2448); pfam10476
PI3-kinase family, p85-binding domain; pfam02192
PI3-kinase family, ras-binding domain; pfam00794
C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks); cd08693
Phosphoinositide 3-kinase family, accessory domain (PIK domain); smart00145
Phosphoinositide 3-kinase (PI3K), class IA, delta isoform, catalytic domain; The PI3K catalytic domain family is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein...; cd05174
Phosphoinositide 3-kinase, catalytic domain; smart00146
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Concanavalin A-like lectin/glucanases superfamily; pfam13385
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Concanavalin A-like lectin/glucanases superfamily; pfam13385
Beta-catenin-interacting protein ICAT; pfam06384
Beta-catenin-interacting protein ICAT; pfam06384
Beta-catenin-interacting protein ICAT; pfam06384
Nicotinamide/nicotinate mononucleotide adenylyltransferase, Eukaryotic; cd09286
nicotinate (nicotinamide) nucleotide adenylyltransferase
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Ubiquitin elongating factor core; pfam10408
U-box domain; pfam04564
Ubiquitin elongating factor core; pfam10408
U-box domain; pfam04564
Kinesin motor domain, KIF1_like proteins. KIF1A (Unc104) transports synaptic vesicles to the nerve terminal, KIF1B has been implicated in transport of mitochondria. Both proteins are expressed in neurons. This catalytic (head) domain has ATPase activity...; cd01365
Kinesin motor, catalytic domain. ATPase; smart00129
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
Kinesin protein 1B; pfam12423
Kinesin protein; pfam12473
Unc-104 pleckstrin homology (PH) domain; cd01233
Kinesin motor domain, KIF1_like proteins. KIF1A (Unc104) transports synaptic vesicles to the nerve terminal, KIF1B has been implicated in transport of mitochondria. Both proteins are expressed in neurons. This catalytic (head) domain has ATPase activity...; cd01365
Kinesin motor, catalytic domain. ATPase; smart00129
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
6-phosphogluconate dehydrogenase; Validated
6-phosphogluconate dehydrogenase, C-terminal domain; pfam00393
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cl00074
Somatostatin/Cortistatin family; pfam03002
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cl00074
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cl00074
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cl00074
Somatostatin/Cortistatin family; pfam03002
Somatostatin/Cortistatin family; pfam03002
CIDE_N domain of ICAD. The CIDE_N  (cell death-inducing DFF45-like effector, N-terminal) domain is found at the N-terminus of the CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD (DFF45). These proteins are...; cd06536
DNA Fragmentation factor 45kDa, C terminal domain; pfam09033
CIDE_N domain of ICAD. The CIDE_N  (cell death-inducing DFF45-like effector, N-terminal) domain is found at the N-terminus of the CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD (DFF45). These proteins are...; cd06536
DNA Fragmentation factor 45kDa, C terminal domain; pfam09033
Peroxisomal membrane anchor protein (Pex14p) conserved region; pfam04695
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
spermidine synthase; Provisional
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
PMC2NT (NUC016) domain; pfam08066
DEDDy 3'-5' exonuclease domain of yeast Rrp6p, human polymyositis/scleroderma autoantigen 100kDa, and similar proteins; cd06147
Helicase and RNase D C-terminal; smart00341
PMC2NT (NUC016) domain; pfam08066
DEDDy 3'-5' exonuclease domain of yeast Rrp6p, human polymyositis/scleroderma autoantigen 100kDa, and similar proteins; cd06147
Helicase and RNase D C-terminal; smart00341
Phosphatidylinositol kinase and protein kinases of the PI-3 kinase family [Signal transduction mechanisms / Cell division and chromosome partitioning / Chromatin structure and dynamics / DNA replication, recombination, and repair / Intracellular...; COG5032
Domain of unknown function (DUF3385); pfam11865
Rapamycin binding domain; pfam08771
TOR (Target of rapamycin), catalytic domain; The TOR catalytic domain subfamily is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein kinases (PKs), aminoglycoside...; cd05169
Phosphoinositide 3-kinase, catalytic domain; smart00146
FATC domain; pfam02260
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
UbiA prenyltransferase family; cl00337
Predicted exporters of the RND superfamily [General function prediction only]
Predicted exporters of the RND superfamily [General function prediction only]
F-box associated region; pfam04300
F-box-like; pfam12937
F-box associated region; pfam04300
F-box-like; pfam12937
F-box associated region; pfam04300
F-box-like; pfam12937
F-box associated region; pfam04300
F-box-like; pfam12937
F-box associated region; pfam04300
F-box-like; pfam12937
F-box associated region; pfam04300
HORMA domain; pfam02301
HORMA domain; pfam02301
Angiotensin II, type I receptor-associated protein; smart00805
Angiotensin II, type I receptor-associated protein; smart00805
Angiotensin II, type I receptor-associated protein (AGTRAP); cl05741
Angiotensin II, type I receptor-associated protein (AGTRAP); cl05741
Methylenetetrahydrofolate reductase; pfam02219
Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; cd00537
ClC-6-like chloride channel proteins. This CD includes ClC-6, ClC-7 and ClC-B, C, D in plants. Proteins in this family are ubiquitous in eukarotes and their functions are unclear. They are expressed in intracellular organelles membranes.  This family...; cd03685
Voltage gated chloride channel; pfam00654
Voltage gated chloride channel; pfam00654
CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; cl02915
Domain in cystathionine beta-synthase and other proteins; smart00116
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of...; cd04591
FOG: CBS domain [General function prediction only]
ClC-6-like chloride channel proteins. This CD includes ClC-6, ClC-7 and ClC-B, C, D in plants. Proteins in this family are ubiquitous in eukarotes and their functions are unclear. They are expressed in intracellular organelles membranes.  This family...; cd03685
Voltage gated chloride channel; pfam00654
Voltage gated chloride channel; pfam00654
CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; cl02915
Domain in cystathionine beta-synthase and other proteins; smart00116
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of...; cd04591
FOG: CBS domain [General function prediction only]
Natriuretic peptide; smart00183
Atrial natriuretic peptide; pfam00212
Uncharacterized conserved protein (DUF2152); pfam10222
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam03171
Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; cd09912
Dynamin family; pfam00350
fzo-like conserved region; pfam04799
Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; cd09912
Dynamin family; pfam00350
fzo-like conserved region; pfam04799
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cl12111
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cl12111
N-terminal region of Chorein, a TM vesicle-mediated sorter; pfam12624
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Protein of unknown function (DUF1162); pfam06650
N-terminal region of Chorein, a TM vesicle-mediated sorter; pfam12624
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Protein of unknown function (DUF1162); pfam06650
Short-chain dehydrogenases of various substrate specificities [General function prediction only]; COG0300
human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs; cd05339
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
alpha/beta hydrolase fold; pfam07859
alpha/beta hydrolase fold; pfam07859
alpha/beta hydrolase fold; pfam07859
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Podoplanin; pfam05808
Podoplanin; pfam05808
Podoplanin; pfam05808
Podoplanin; pfam05808
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Zinc finger, C2H2 type; cl15478
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Zinc finger, C2H2 type; cl15478
Zinc finger, C2H2 type; cl15478
TPR/MLP1/MLP2-like protein; pfam07926
SAM domain of kazrin proteins repeat 1; cd09564
Sterile alpha motif; smart00454
SAM domain of kazrin proteins repeat 2; cd09567
Sterile alpha motif; smart00454
SAM domain of kazrin proteins repeat 3; cd09570
SAM domain (Sterile alpha motif); pfam07647
TPR/MLP1/MLP2-like protein; pfam07926
TPR/MLP1/MLP2-like protein; pfam07926
chromosome segregation protein SMC, common bacterial type; TIGR02168
chromosome segregation protein SMC, common bacterial type; TIGR02168
FOG: FHA domain [Signal transduction mechanisms]
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Caspase activation and recruitment domain of Caspase-9; cd08326
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
TRX domain, DnaJ domain containing protein family; composed of uncharacterized proteins of about 500-800 amino acids, containing an N-terminal DnaJ domain followed by one redox active TRX domain. DnaJ is a member of the 40 kDa heat-shock protein (Hsp40)...; cd02963
Agmatinase-like family includes proclavaminic acid amidinohydrolase; cd11592
DNA damage inducible protein 1 ubiquitin-like domain; cd01796
Ubiquitin family; pfam00240
RP_DDI; retropepsin-like domain of DNA damage inducible protein; cd05479
Ubiquitin associated domain; smart00165
RUN domain; pfam02759
Pleckstrin homology (PH) domain; cd00821
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1); cd09372
The third LIM domain of Zyxin-like family; cd09357
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1); cd09372
The third LIM domain of Zyxin-like family; cd09357
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1); cd09372
Ubiquinol-cytochrome C reductase hinge protein; pfam02320
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
SMRT interacting domain/repression domain
SPOC domain; pfam07744
BTB/POZ domain; pfam00651
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; COG0071
Alpha crystallin domain (ACD) found in mammalian small heat shock protein (sHsp) HspB7, also known as cardiovascular small heat shock protein (cvHsp), and similar proteins. sHsps are molecular chaperones that suppress protein aggregation and protect...; cd06479
ClC-1-like chloride channel proteins. This CD includes isoforms ClC-0, ClC-1, ClC-2 and ClC_K. ClC-1 is expressed in skeletal muscle and its mutation leads to both recessively and dominantly-inherited forms of muscle stiffness or myotonia. ClC-K is...; cd03683
Voltage gated chloride channel; pfam00654
CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; cl02915
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of...; cd04591
CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; cl02915
Voltage gated chloride channel; pfam00654
CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; cl02915
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of...; cd04591
CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; cl02915
Voltage gated chloride channel; pfam00654
CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; cl02915
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of...; cd04591
CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; cl02915
Voltage gated chloride channel; pfam00654
CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; cl02915
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of...; cd04591
Voltage gated chloride channel; pfam00654
CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; cl02915
CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; cl02915
This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of...; cd04591
Ligand Binding Domain of Ephrin type-A Receptor 2; cd10480
GCC2 and GCC3; pfam07699
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Catalytic domain of the Protein Tyrosine Kinase, Ephrin Receptor A2; cd05063
Protein tyrosine kinase; pfam07714
SAM domain of EPH-A2 family of tyrosine kinase receptors; cd09543
Sterile alpha motif; smart00454
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
Src homology 3 domain of the Rho guanine nucleotide exchange factors ARHGEF5 and ARHGEF19; cd11940
GTPase SAR1 and related small G proteins [General function prediction only]
Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); cd00882
F-box-like; pfam12937
Galactose oxidase, central domain; pfam13415
Kelch motif; pfam13854
SUZ domain; pfam12752
SUZ-C motif; pfam12901
SUZ domain; pfam12752
SUZ-C motif; pfam12901
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13833
Protein of unknown function (DUF1681); pfam07933
Protein of unknown function (DUF1681); pfam07933
Protein of unknown function (DUF1681); pfam07933
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
chromosome segregation protein SMC, common bacterial type; TIGR02168
chromosome segregation protein SMC, primarily archaeal type; TIGR02169
chromosome segregation protein SMC, common bacterial type; TIGR02168
Microfibril-associated glycoprotein (MAGP); pfam05507
Microfibril-associated glycoprotein (MAGP); pfam05507
Microfibril-associated glycoprotein (MAGP); pfam05507
Microfibril-associated glycoprotein (MAGP); pfam05507
P-type ATPase of unknown pump specificity (type V); TIGR01657
P5-type ATPase cation transporter; pfam12409
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid Dehalogenase-like Hydrolases; cl11391
P-type ATPase of unknown pump specificity (type V); TIGR01657
P5-type ATPase cation transporter; pfam12409
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid Dehalogenase-like Hydrolases; cl11391
P-type ATPase of unknown pump specificity (type V); TIGR01657
P5-type ATPase cation transporter; pfam12409
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid Dehalogenase-like Hydrolases; cl11391
succinate dehydrogenase iron-sulfur subunit; Reviewed; PRK05950
2Fe-2S iron-sulfur cluster binding domain; pfam13085
Protein-arginine deiminase (PAD) N-terminal domain; pfam08526
Protein-arginine deiminase (PAD) middle domain; pfam08527
Protein-arginine deiminase (PAD); pfam03068
Protein-arginine deiminase (PAD) N-terminal domain; pfam08526
Protein-arginine deiminase (PAD) middle domain; pfam08527
Protein-arginine deiminase (PAD); pfam03068
Protein-arginine deiminase (PAD) N-terminal domain; pfam08526
Protein-arginine deiminase (PAD) middle domain; pfam08527
Protein-arginine deiminase (PAD); pfam03068
Protein-arginine deiminase (PAD) N-terminal domain; pfam08526
Protein-arginine deiminase (PAD) middle domain; pfam08527
Protein-arginine deiminase (PAD); pfam03068
Protein-arginine deiminase (PAD) N-terminal domain; pfam08526
Protein-arginine deiminase (PAD) middle domain; pfam08527
Protein-arginine deiminase (PAD); pfam03068
Regulator of chromosome condensation (RCC1) repeat; pfam13540
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam13540
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Actin; smart00268
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Kelch motif; pfam01344
Kelch motif; pfam01344
Paired Box domain; cd00131
'Paired box' domain; pfam00292
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Paired box protein 7; pfam12360
Paired Box domain; cd00131
'Paired box' domain; pfam00292
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Paired box protein 7; pfam12360
Paired Box domain; cd00131
'Paired box' domain; pfam00292
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Paired box protein 7; pfam12360
Ligand-binding domain of the T1R taste receptor; cd06363
Receptor family ligand binding region; pfam01094
Type 1 periplasmic binding fold superfamily; cl10011
Nine Cysteines Domain of family 3 GPCR; pfam07562
7 transmembrane sweet-taste receptor of 3 GCPR; pfam00003
Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17; cd07123
delta-1-pyrroline-5-carboxylate dehydrogenase, group 1; TIGR01236
Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17; cd07123
delta-1-pyrroline-5-carboxylate dehydrogenase, group 1; TIGR01236
delta-1-pyrroline-5-carboxylate dehydrogenase, group 1; TIGR01236
Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17; cd07123
Intermediate filament protein; pfam00038
Putative zinc finger in N-recognin, a recognition component of the N-end rule pathway; smart00396
E3 ubiquitin-protein ligase UBR4; pfam13764
Protein of unknown function (DUF1620); pfam07774
PQQ-like domain; pfam13360
Protein of unknown function (DUF1620); pfam07774
PQQ-like domain; pfam13360
Protein of unknown function (DUF1620); pfam07774
PQQ-like domain; pfam13360
Protein of unknown function (DUF1620); pfam07774
Ribosomal protein L10 family, P0-like protein subfamily; composed of uncharacterized eukaryotic proteins with similarity to the 60S ribosomal protein P0, including the Saccharomyces cerevisiae protein called mRNA turnover protein 4 (MRT4). MRT4 may be...; cd05796
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; COG0667
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Aldo/keto reductase family; pfam00248
PQ loop repeat; pfam04193
PQ loop repeat; pfam04193
PQ loop repeat; pfam04193
PQ loop repeat; pfam04193
PQ loop repeat; pfam04193
F-actin capping protein, beta subunit; pfam01115
F-actin capping protein, beta subunit; pfam01115
Domain of unknown function (DUF543); pfam04418
Domain of unknown function (DUF543); pfam04418
Domain of unknown function (DUF543); pfam04418
DAN domain; pfam03045
DAN domain; pfam03045
DAN domain; pfam03045
DAN domain; pfam03045
DAN domain; pfam03045
DAN domain; pfam03045
DAN domain; pfam03045
7 transmembrane receptor (rhodopsin family); pfam00001
Protein of unknown function (DUF726); pfam05277
Ring finger domain; pfam13639
OTU-like cysteine protease; pfam02338
PLA2c: Phospholipase A2, a family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a...; cd00125
PLA2c: Phospholipase A2, a family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a...; cd00125
PLA2c: Phospholipase A2, a family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a...; cd00125
PLA2c: Phospholipase A2, a family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a...; cd00125
PLA2c: Phospholipase A2, a family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a...; cd00125
PLA2c: Phospholipase A2, a family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a...; cd00125
PLA2c: Phospholipase A2, a family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a...; cd00125
PLA2c: Phospholipase A2, a family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a...; cd00125
PLA2_like: Phospholipase A2, a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a...; cl05417
Ubiquitin-like proteins; cl00155
Vault protein inter-alpha-trypsin domain; pfam13757
marine proteobacterial sortase target protein; TIGR03788
vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to...; cd01461
E3 Ubiquitin ligase; pfam12483
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
Pleckstrin homology-like domain; cl00273
Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; cd01283
Catalytic domain of Protein Kinases; cd00180
Oligosaccharyltransferase 48 kDa subunit beta; pfam03345
Kinesin motor domain, kinesins II or KIF3_like proteins. Subgroup of kinesins, which form heterotrimers composed of 2 kinesins and one non-motor accessory subunit. Kinesins II play important roles in ciliary transport, and have been implicated in...; cd01371
Kinesin motor, catalytic domain. ATPase; smart00129
Kinesin motor domain, kinesins II or KIF3_like proteins. Subgroup of kinesins, which form heterotrimers composed of 2 kinesins and one non-motor accessory subunit. Kinesins II play important roles in ciliary transport, and have been implicated in...; cd01371
Kinesin motor, catalytic domain. ATPase; smart00129
Pleckstrin homology-like domain; cl00273
Src homology 2 (SH2) domain; cd00173
Src homology 2 (SH2) domain; cd00173
linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated...; cd00073
Domain in histone families 1 and 5; smart00526
Domain in histone families 1 and 5; smart00526
MIF4G domain; pfam02854
MA3 domain; pfam02847
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; cd11559
C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon; cl17013
MIF4G domain; pfam02854
MA3 domain; pfam02847
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; cd11559
C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon; cl17013
MIF4G domain; pfam02854
MA3 domain; pfam02847
C-terminal W2 domain of eukaryotic translation initiation factor 4 gamma 1 and similar proteins; cd11559
C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon; cl17013
Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; COG3590
Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; cd08662
Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; COG3590
Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; cd08662
Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; COG3590
Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; cd08662
Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; COG3590
Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; cd08662
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; cd00016
Alkaline phosphatase homologues; smart00098
Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; cd00016
Alkaline phosphatase homologues; smart00098
Alkaline phosphatase homologues; smart00098
Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; cd00016
GoLoco motif; pfam02188
Rap/ran-GAP; pfam02145
GoLoco motif; pfam02188
Rap/ran-GAP; pfam02145
GoLoco motif; pfam02188
Rap/ran-GAP; pfam02145
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02668
DUSP domain; pfam06337
USP ubiquitin-specific protease; cd01795
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02668
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cl00049
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Domain found in sea urchin sperm protein, enterokinase, agrin; smart00200
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain II (D2) of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2; cd05743
Laminin B domain; smart00281
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin EGF-like (Domains III and V); pfam00053
Laminin B domain; smart00281
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin B domain; smart00281
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Third immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; cd05754
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin domain; pfam13895
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
GTPase SAR1 and related small G proteins [General function prediction only]
cell division cycle 42 (Cdc42) is a small GTPase of the Rho family; cd01874
GTPase SAR1 and related small G proteins [General function prediction only]
cell division cycle 42 (Cdc42) is a small GTPase of the Rho family; cd01874
GTPase SAR1 and related small G proteins [General function prediction only]
cell division cycle 42 (Cdc42) is a small GTPase of the Rho family; cd01874
wnt family; pfam00110
found in Wnt-1; smart00097
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Ligand Binding Domain of Ephrin type-A Receptor 8; cd10486
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein Kinases, catalytic domain; cl09925
Protein tyrosine kinase; pfam07714
SAM domain of EPH-A8 subfamily of tyrosine kinase receptors; cd09550
Sterile alpha motif; smart00454
Ligand Binding Domain of Ephrin type-A Receptor 8; cd10486
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Collagen triple helix repeat (20 copies); pfam01391
Complement component C1q domain; smart00110
Complement component C1q domain; smart00110
Complement component C1q domain; smart00110
Complement component C1q domain; smart00110
Ligand Binding Domain of Ephrin type-B Receptor 2; cd10477
GCC2 and GCC3; pfam07699
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Catalytic domain of the Protein Tyrosine Kinases, Class EphB Ephrin Receptors; cd05065
Protein tyrosine kinase; pfam07714
SAM domain of EPH-B2 subfamily of tyrosine kinase receptors; cd09552
Sterile alpha motif; smart00454
Ligand Binding Domain of Ephrin type-B Receptor 2; cd10477
GCC2 and GCC3; pfam07699
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Catalytic domain of the Protein Tyrosine Kinases, Class EphB Ephrin Receptors; cd05065
Protein tyrosine kinase; pfam07714
SAM domain of EPH-B2 subfamily of tyrosine kinase receptors; cd09552
Sterile alpha motif; smart00454
SWIRM domain; pfam04433
NAD(P)-binding Rossmann-like domain; pfam13450
Domain of unknown function (DUF4201); pfam13870
SWIRM domain; pfam04433
NAD(P)-binding Rossmann-like domain; pfam13450
Domain of unknown function (DUF4201); pfam13870
chromosome segregation protein SMC, common bacterial type; TIGR02168
chromosome segregation protein SMC, common bacterial type; TIGR02168
7 transmembrane receptor (rhodopsin family); pfam00001
heterogeneous nuclear ribonucleoprotein R, Q family; TIGR01648
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme; cd00183
transcription elongation factor S-II; TIGR01385
Transcription factor S-II (TFIIS), central domain; pfam07500
Transcription factor S-II (TFIIS); pfam01096
The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 3; cd07640
Centaurin Pleckstrin homology (PH) domain; cd01250
Putative GTPase activating protein for Arf; pfam01412
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13857
The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 3; cd07640
Centaurin Pleckstrin homology (PH) domain; cd01250
Putative GTPase activating protein for Arf; pfam01412
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13857
E2F/DP family winged-helix DNA-binding domain; pfam02319
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
60S ribosomal protein L11; Provisional
Ribosomal protein L5; pfam00281
ribosomal L5P family C-terminus; pfam00673
60S ribosomal protein L11; Provisional
Ribosomal protein L5; pfam00281
ribosomal L5P family C-terminus; pfam00673
N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme; cd00183
RNA polymerase II transcription factor SIII (Elongin) subunit A; pfam06881
PITH domain; pfam06201
Phospholipase/Carboxylesterase; pfam02230
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
UDP-glucose 4-epimerase
UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; cd05247
UDP-glucose 4-epimerase
UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; cd05247
UDP-glucose 4-epimerase
UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; cd05247
DRE-TIM metallolyase superfamily; cl07974
hydroxymethylglutaryl-CoA lyase
Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism]; COG0119
3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain; cd07938
Alpha-L-fucosidase; smart00812
Alpha-L-fucosidase [Carbohydrate transport and metabolism]
7 transmembrane receptor (rhodopsin family); pfam00001
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Tissue factor; pfam01108
Tissue factor; pfam01108
Tissue factor; pfam01108
Tissue factor; pfam01108
CP2 transcription factor; pfam04516
CP2 transcription factor; pfam04516
CP2 transcription factor; pfam04516
CP2 transcription factor; pfam04516
Magnesium transporter NIPA; pfam05653
Calcipressin; pfam04847
Calcipressin; pfam04847
Calcipressin; pfam04847
Calcipressin; pfam04847
Calcipressin; pfam04847
Calcipressin; pfam04847
Calcipressin; pfam04847
Calcipressin; pfam04847
Calcipressin; pfam04847
PWI domain; pfam01480
GST_N family, Chloride Intracellular Channel (CLIC) subfamily; composed of CLIC1-5, p64, parchorin and similar proteins. They are auto-inserting, self-assembling intracellular anion channels involved in a wide variety of functions including regulated...; cd03061
intracellular chloride channel protein; TIGR00862
C-terminal, alpha helical domain of Chloride Intracellular Channel 4; cd10296
Runt domain; pfam00853
Runx inhibition domain; pfam08504
Runt domain; pfam00853
Runx inhibition domain; pfam08504
SYF2 splicing factor; pfam08231
SYF2 splicing factor; pfam08231
Ammonium Transporter Family; cl03012
Ammonium Transporter Family; cl03012
Uncharacterized protein family (UPF0220); pfam05255
Ammonium Transporter Family; cl03012
Ammonium Transporter Family; cl03012
Ammonium Transporter Family; cl03012
Ammonium Transporter Family; cl03012
Ammonium Transporter Family; cl03012
Transmembrane protein; pfam09726
lycopene cyclase domain; TIGR03462
Phosphotyrosine-binding (PTB) domain; cd00934
Glycosyl hydrolase family 47; pfam01532
Putative binding domain; pfam13900
Mitochondrial fission regulator; pfam05308
Mitochondrial fission regulator; pfam05308
Mitochondrial fission regulator; pfam05308
Mitochondrial fission regulator; pfam05308
Haemolysin-III related; pfam03006
Stathmin family; pfam00836
Stathmin family; pfam00836
Stathmin family; pfam00836
Stathmin family; pfam00836
Platelet-activating factor acetylhydrolase, isoform II; pfam03403
Alpha/beta hydrolase family; pfam12695
Exostosin family; pfam03016
Glycosyl transferase family 64 domain; pfam09258
Cation efflux family; pfam01545
cation diffusion facilitator family transporter; TIGR01297
Cation efflux family; pfam01545
cation diffusion facilitator family transporter; TIGR01297
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
B-Box C-terminal domain; smart00502
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Centrosome-associated N terminus; pfam14161
Centrosome-associated C terminus; pfam14160
Zinc-finger double-stranded RNA-binding; cl09952
SAM domain of CNK1,2,3-suppressor subfamily; cd09511
Sterile alpha motif; smart00454
Connector enhancer of kinase suppressor of ras; pfam10534
PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; cd00136
Connector enhancer of KSR (Kinase suppressor of ras)  (CNK) pleckstrin homology (PH) domain; cd01260
Ion transport protein; pfam00520
Protein-interacting V-domain of mammalian Alix and related domains; cl14654
Glutaredoxin (GRX) family, SH3BGR (SH3 domain binding glutamic acid-rich protein) subfamily; a recently-identified subfamily composed of SH3BGR and similar proteins possessing significant sequence similarity to GRX, but without a redox active CXXC motif; cd03030
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
SEP domain; pfam08059
UBX domain; pfam00789
SEP domain; pfam08059
UBX domain; pfam00789
Ubiquitin-like proteins; cl00155
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
SEP domain; pfam08059
UBX domain; pfam00789
Ubiquitin-like proteins; cl00155
DNA polymerase III subunits gamma and tau; Validated
Beta/Gamma crystallin; pfam00030
Beta/Gamma crystallin; pfam00030
Beta/Gamma crystallin; pfam00030
Beta/Gamma crystallin; pfam00030
Beta/Gamma crystallin; pfam00030
Beta/Gamma crystallin; pfam00030
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; cd00475
Putative undecaprenyl diphosphate synthase; pfam01255
Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; cd00475
Putative undecaprenyl diphosphate synthase; pfam01255
Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; cl00230
Putative undecaprenyl diphosphate synthase; pfam01255
Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; cl00230
Putative undecaprenyl diphosphate synthase; pfam01255
Serine/Threonine protein kinases, catalytic domain; smart00220
N-terminal catalytic domain of the Protein Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase; cd05582
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
N-terminal catalytic domain of the Protein Serine/Threonine Kinase, 90 kDa ribosomal protein S6 kinase; cd05582
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
ARID/BRIGHT DNA binding domain; pfam01388
Domain of unknown function (DUF3518); pfam12031
ARID/BRIGHT DNA binding domain; pfam01388
Domain of unknown function (DUF3518); pfam12031
Mannosyltransferase (PIG-V)); pfam04188
Mannosyltransferase (PIG-V)); pfam04188
DHHC palmitoyltransferase; pfam01529
14-3-3 sigma, an isoform of 14-3-3 protein; cd10019
Conserved hypothetical ATP binding protein; pfam03029
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
glycine rich nucleic binding domain; smart00443
The ligand binding domain of DAX1 protein, a nuclear receptor lacking DNA binding domain; cd07349
N-terminal conserved domain of Nudc; pfam14050
p23-like NUD (nuclear distribution) C-like domain of mammalian(m) NUDC and similar proteins. Mammalian(m) NUDC associates both with the dynein complex and also with an anti-inflammatory enzyme, platelet activating factor acetylhydrolase I, PAF-AH(I)...; cd06492
Domain of unknown function (DUF1693); pfam07984
sodium/hydrogen exchanger 3; TIGR00840
Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; cl10482
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13432
Tetratricopeptide repeat; pfam13432
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Protein of unknown function (DUF778); pfam05608
C2 domain first repeat present in Synaptotagmin-like proteins 1 and 2; cd08393
C2 domain second repeat present in Synaptotagmin-like proteins 1-4; cd04020
C2 domain first repeat present in Synaptotagmin-like proteins 1 and 2; cd08393
C2 domain second repeat present in Synaptotagmin-like proteins 1-4; cd04020
Domain of unknown function (DUF4071); pfam13281
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
Multi-glycosylated core protein 24 (MGC-24); pfam05283
7 transmembrane receptor (rhodopsin family); pfam00001
also known as verprolin homology domain
DNA polymerase III subunits gamma and tau; Provisional
Src Homology 3 domain superfamily; cl17036
Src homology 2 (SH2) domain found in Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, Fgr; cd10367
Catalytic domain of Src kinase-like Protein Tyrosine Kinases; cd05034
Protein tyrosine kinase; pfam07714
Src Homology 3 domain superfamily; cl17036
Src homology 2 (SH2) domain found in Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, Fgr; cd10367
Catalytic domain of Src kinase-like Protein Tyrosine Kinases; cd05034
Protein tyrosine kinase; pfam07714
Src Homology 3 domain superfamily; cl17036
Src homology 2 (SH2) domain found in Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, Fgr; cd10367
Catalytic domain of Src kinase-like Protein Tyrosine Kinases; cd05034
Protein tyrosine kinase; pfam07714
Interferon-induced 6-16 family; pfam06140
Interferon-induced 6-16 family; pfam06140
Interferon-induced 6-16 family; pfam06140
Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may...; cd00179
Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in...; cd00193
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
Cell-cycle sustaining, positive selection; pfam12736
Cell-cycle sustaining, positive selection; pfam12736
Cell-cycle sustaining, positive selection; pfam12736
Cell-cycle sustaining, positive selection; pfam12736
Single-stranded DNA-binding replication protein A (RPA), medium (30 kD) subunit [DNA replication, recombination, and repair]; COG5235
RPA2_DBD_D: A subfamily of OB folds corresponding to the OB fold of the central ssDNA-binding domain (DBD)-D of human RPA2 (also called RPA32). RPA2 is a subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which appears...; cd04478
Replication protein A C terminal; pfam08784
Calcineurin-like phosphoesterase; pfam00149
acid sphingomyelinase and related proteins, metallophosphatase domain; cd00842
Calcineurin-like phosphoesterase; pfam00149
acid sphingomyelinase and related proteins, metallophosphatase domain; cd00842
XK-related protein; pfam09815
eyes absent protein conserved domain; TIGR01658
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
Mitochondrial ATPase inhibitor, IATP; pfam04568
Mitochondrial ATPase inhibitor, IATP; pfam04568
Mitochondrial ATPase inhibitor, IATP; pfam04568
PA26 p53-induced protein (sestrin); pfam04636
Med18 protein; pfam09637
Med18 protein; pfam09637
RPEL repeat; pfam02755
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2; smart00707
RPEL repeat; cl15286
RPEL repeat; pfam02755
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2; smart00707
RPEL repeat; cl15286
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; COG5184
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam13540
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam13540
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Rab family protein; Provisional
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
TATA Binding Protein (TBP) Associated Factor 12 (TAF12) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex; cd07981
TATA Binding Protein (TBP) Associated Factor 12 (TAF12) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex; cd07981
SAND domain; pfam01342
SAND domain; pfam01342
YT521-B-like domain; pfam04146
YT521-B-like domain; pfam04146
YT521-B-like domain; pfam04146
7 transmembrane receptor (rhodopsin family); pfam00001
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
FERM adjacent (FA); pfam08736
SAB domain; pfam04382
4.1 protein C-terminal domain (CTD); pfam05902
Band 4.1 homologues; smart00295
FERM central domain; pfam00373
FERM_C domain; cd00836
FERM adjacent (FA); pfam08736
SAB domain; pfam04382
4.1 protein C-terminal domain (CTD); pfam05902
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
FERM adjacent (FA); pfam08736
SAB domain; pfam04382
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
FERM adjacent (FA); pfam08736
SAB domain; pfam04382
4.1 protein C-terminal domain (CTD); pfam05902
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
FERM adjacent (FA); pfam08736
SAB domain; pfam04382
4.1 protein C-terminal domain (CTD); pfam05902
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
FERM adjacent (FA); pfam08736
SAB domain; pfam04382
4.1 protein C-terminal domain (CTD); pfam05902
Uncharacterized conserved protein (DUF2371); pfam10177
Uncharacterized conserved protein (DUF2371); pfam10177
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
2-enoyl thioester reductase (ETR); cd08290
NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; COG0604
2-enoyl thioester reductase (ETR); cd08290
Enoylreductase; smart00829
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Fibronectin type III domain; pfam00041
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Fibronectin type III domain; pfam00041
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Fibronectin type III domain; pfam00041
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Fibronectin type III domain; pfam00041
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
VWA_Matrilin: In cartilaginous plate, extracellular matrix molecules mediate cell-matrix and matrix-matrix interactions thereby providing tissue integrity. Some members of the matrilin family are expressed specifically in developing cartilage rudiments; cd01475
VWA_Matrilin: In cartilaginous plate, extracellular matrix molecules mediate cell-matrix and matrix-matrix interactions thereby providing tissue integrity. Some members of the matrilin family are expressed specifically in developing cartilage rudiments; cd01475
Golgi 4-transmembrane spanning transporter; TIGR00799
Syndecan domain; pfam01034
putative band 4.1 homologues' binding motif; smart00294
Pumilio-family RNA binding domain; cd07920
RNA-binding protein of the Puf family, translational repressor [Translation, ribosomal structure and biogenesis]
Pumilio-family RNA binding domain; cd07920
RNA-binding protein of the Puf family, translational repressor [Translation, ribosomal structure and biogenesis]
Na,K-Atpase Interacting protein; pfam05640
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
S1_pNO40: pNO40 , S1-like RNA-binding domain. pNO40 is a nucleolar protein of unknown function with an N-terminal S1 RNA binding domain, a CCHC type zinc finger, and clusters of basic amino acids representing a potential nucleolar targeting signal; cd05686
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Serine incorporator (Serinc); pfam03348
Serine incorporator (Serinc); pfam03348
Serine incorporator (Serinc); pfam03348
Serine incorporator (Serinc); pfam03348
Serine incorporator (Serinc); pfam03348
Somatomedin B domain; cl02508
von Willebrand factor type C domain; cl02515
Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an...; cd02620
Somatomedin B domain; cl02508
Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an...; cd02620
von Willebrand factor type C domain; cl02515
Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an...; cd02620
7 transmembrane receptor (rhodopsin family); pfam00001
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Thrombospondin N-terminal -like domains; smart00210
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Domain present in hormone receptors; smart00008
Domain of unknown function (DUF3497); pfam12003
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
Transcription factor S-II (TFIIS), central domain; pfam07500
SPOC domain; pfam07744
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cl00053
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cl00053
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cl00053
Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1...; cd02395
Putative transmembrane protein; pfam10271
Importin beta binding domain; pfam01749
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
HEAT-like repeat; pfam13513
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
HEAT-like repeat; pfam13513
HEAT-like repeat; pfam13513
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Myosin-like coiled-coil protein; pfam09728
Domain of unknown function (DUF4061); pfam13270
Ubiquitin-like domain of DCX; cd01617
Ubiquitin-like proteins; cl00155
Uncharacterized protein family UPF0546; pfam10639
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Src homology 3 domain of Lck Protein Tyrosine Kinase; cd12005
Src homology 2 (SH2) domain in lymphocyte cell kinase (Lck); cd10362
Catalytic domain of the Protein Tyrosine Kinases, Lymphocyte-specific kinase and Blk; cd05067
Protein tyrosine kinase; pfam07714
Src homology 3 domain of Lck Protein Tyrosine Kinase; cd12005
Src homology 2 (SH2) domain in lymphocyte cell kinase (Lck); cd10362
Catalytic domain of the Protein Tyrosine Kinases, Lymphocyte-specific kinase and Blk; cd05067
Protein tyrosine kinase; pfam07714
Histone deacetylase 1 (HDAC1); cd10010
Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; COG0123
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
BSD domain; pfam03909
BSD domain; pfam03909
BSD domain; pfam03909
BSD domain; pfam03909
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
BTB/POZ domain; pfam00651
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Archease protein family (MTH1598/TM1083); pfam01951
Histone-binding protein RBBP4 or subunit C of CAF1 complex; pfam12265
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Histone-binding protein RBBP4 or subunit C of CAF1 complex; pfam12265
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Histone-binding protein RBBP4 or subunit C of CAF1 complex; pfam12265
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
tyrosyl-tRNA synthetase; TIGR00234
catalytic core domain of tyrosinyl-tRNA synthetase; cd00805
tRNA-binding-domain-containing EMAP2-like proteins. This family contains a diverse fraction of tRNA binding proteins, including Caenorhabditis elegans methionyl-tRNA synthetase (CeMetRS), human tyrosyl- tRNA synthetase (hTyrRS), Saccharomyces cerevisiae...; cd02799
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cl08302
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Beta-casein like protein; pfam12304
Ring finger domain; pfam13639
IBR domain; pfam01485
In Between Ring fingers; smart00647
IBR domain; pfam01485
Ring finger domain; pfam13639
IBR domain; pfam01485
In Between Ring fingers; smart00647
IBR domain; pfam01485
adenylate kinase; Reviewed; PRK00279
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; cd01428
adenylate kinase; Reviewed; PRK00279
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; cd01428
adenylate kinase; Reviewed; PRK00279
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; cd01428
Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Ornithine Decarboxylase; cd00622
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
B-Box C-terminal domain; smart00502
SPRY-associated domain; pfam13765
Domain in SPla and the RYanodine Receptor; smart00449
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SAM domain of Ph (polyhomeotic) proteins of Polycomb group; cd09577
Sterile alpha motif; smart00454
SAM domain of Ph (polyhomeotic) proteins of Polycomb group; cd09577
Sterile alpha motif; smart00454
SCAN oligomerization domain; cd07936
Myb/SANT-like DNA-binding domain; pfam13837
Myb/SANT-like DNA-binding domain; pfam13837
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I...; cd00084
High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I...; cd00084
Connexin; pfam00029
Gap junction channel protein cysteine-rich domain; smart01089
Connexin; pfam00029
Gap junction channel protein cysteine-rich domain; smart01089
Connexin; pfam00029
Gap junction channel protein cysteine-rich domain; smart01089
Connexin; pfam00029
Gap junction channel protein cysteine-rich domain; smart01089
Connexin; pfam00029
Gap junction channel protein cysteine-rich domain; smart01089
Guanylate-kinase-associated protein (GKAP) protein; pfam03359
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
metallochaperone-like domain; smart00746
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
metallochaperone-like domain; smart00746
zinc finger in transposases and transcription factors; smart00597
Domain of unknown function (DUF4371); pfam14291
Domain of unknown function (DUF4371); pfam14291
hAT family dimerisation domain; pfam05699
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
NOPS (NUC059) domain; pfam08075
MYM-type Zinc finger with FCS sequence motif; pfam06467
metallochaperone-like domain; smart00746
Ribosomal protein L24e/L24 is a ribosomal protein found in eukaryotes (L24) and in archaea (L24e, distinct from archaeal L24). L24e/L24 is located on the surface of the large subunit, adjacent to proteins L14 and L3, and near the translation factor...; cl00909
Ribosomal protein L24e/L24 is a ribosomal protein found in eukaryotes (L24) and in archaea (L24e, distinct from archaeal L24). L24e/L24 is located on the surface of the large subunit, adjacent to proteins L14 and L3, and near the translation factor...; cl00909
Ribosomal protein L24e/L24 is a ribosomal protein found in eukaryotes (L24) and in archaea (L24e, distinct from archaeal L24). L24e/L24 is located on the surface of the large subunit, adjacent to proteins L14 and L3, and near the translation factor...; cl00909
MYM-type Zinc finger with FCS sequence motif; pfam06467
MYM-type Zinc finger with FCS sequence motif; pfam06467
Domain of unknown function (DUF3504); pfam12012
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; cd00146
Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; cl09101
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; cd00146
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; cd00146
Neurochondrin; pfam05536
Neurochondrin; pfam05536
Neurochondrin; pfam05536
Transcription factor AP-2; pfam03299
20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]; COG0638
proteasome beta type-2 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that...; cd03758
proteasome beta type-2 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that...; cd03758
20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]; COG0638
The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; cl00467
protein argonaute; Provisional
Domain of unknown function (DUF1785); pfam08699
PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; cd02846
Piwi_ago-like: PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of...; cd04657
protein argonaute; Provisional
Domain of unknown function (DUF1785); pfam08699
PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; cd02846
Piwi_ago-like: PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of...; cd04657
protein argonaute; Provisional
Domain of unknown function (DUF1785); pfam08699
PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; cd02846
Piwi_ago-like: PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of...; cd04657
PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; cd02846
Piwi_ago-like: PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of...; cd04657
Tektin family; pfam03148
ADP-ribosylglycohydrolase; pfam03747
Complement component C1q domain; smart00110
Transport protein particle (TRAPP) component; pfam04051
Transport protein particle (TRAPP) component; pfam04051
Transport protein particle (TRAPP) component; pfam04051
Transport protein particle (TRAPP) component; pfam04051
Transport protein particle (TRAPP) component; pfam04051
Src Homology 3 domain superfamily; cl17036
Second Src Homology 3 domain (SH3B) of CD2-associated protein and similar proteins; cd11874
Src Homology 3 domain of SH3 domain-containing protein 21 (SH3D21) and similar proteins; cd12142
Src Homology 3 domain superfamily; cl17036
Src Homology 3 domain of SH3 domain-containing protein 21 (SH3D21) and similar proteins; cd12142
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Like-Sm protein 10; cd01733
Organic solute transport protein 1; pfam10188
Organic solute transport protein 1; pfam10188
Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; cd00353
Ig-like C2-type domain; pfam06328
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type III domain; pfam00041
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Ig-like C2-type domain; pfam06328
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type III domain; pfam00041
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Ig-like C2-type domain; pfam06328
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type III domain; pfam00041
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the GluR5-7 subunits of Kainate receptor; cd06393
Receptor family ligand binding region; pfam01094
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Ligand-gated ion channel; pfam00060
Eukaryotic homologues of bacterial periplasmic substrate binding proteins; smart00079
Zc3h12a-like Ribonuclease NYN domain; pfam11977
Histone acetyltransferase subunit NuA4; pfam09340
Histone acetyltransferase subunit NuA4; pfam09340
Histone acetyltransferase subunit NuA4; pfam09340
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
Axonemal dynein light chain; pfam10211
NGP1NT (NUC091) domain; pfam08153
Predicted GTPases [General function prediction only]
A novel nucleolar GTP-binding protein, circularly permuted subfamily of the Ras GTPases; cd01858
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors; cl00066
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors; cl00066
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors; cl00066
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors; cl00066
Nbl1 / Borealin N terminal; pfam10444
Cell division cycle-associated protein 8; pfam10512
Nbl1 / Borealin N terminal; pfam10444
Cell division cycle-associated protein 8; pfam10512
Ligand Binding Domain of Ephrin Receptors; cl02704
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Catalytic domain of the Protein Tyrosine Kinase, Ephrin Receptor A10; cd05064
Protein tyrosine kinase; pfam07714
SAM domain of EPH-A10 subfamily of tyrosine kinase receptors; cd09549
SAM domain (Sterile alpha motif); pfam07647
Ligand Binding Domain of Ephrin Receptors; cl02704
Glycoside hydrolase family 99, an endo-alpha-1,2-mannosidase; cd11574
Glycoside hydrolase families 71, 99, and related domains; cl01529
Glycoside hydrolase family 99, an endo-alpha-1,2-mannosidase; cd11574
Telomere recombination; pfam01300
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of Type II inositol polyphosphate 5-phosphatase I, Oculocerebrorenal syndrome of Lowe 1, and related proteins; cd09093
RhoGAP_OCRL1: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in OCRL1-like proteins. OCRL1 (oculocerebrorenal syndrome of Lowe 1)-like proteins contain two conserved domains: a central inositol polyphosphate...; cd04380
GTPase-activator protein for Rho-like GTPases; smart00324
Splicing factor 3a, subunit 3 [RNA processing and modification]; COG5188
Splicing factor SF3a60 binding domain; pfam12108
Telomere stability C-terminal; pfam13297
Domain of unknown function (DUF3449); pfam11931
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
The first LIM domain of Four and a half LIM domains protein 3 (FHL3); cd09423
The second LIM domain of Four and a half LIM domains protein 3 (FHL3); cd09427
The third LIM domain of Four and a half LIM domains protein (FHL); cd09346
The fourth LIM domain of Four and a half LIM domains protein 3 (FHL3); cd09434
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
The third LIM domain of Four and a half LIM domains protein (FHL); cd09346
The fourth LIM domain of Four and a half LIM domains protein 3 (FHL3); cd09434
Utp11 protein; pfam03998
Found in Pit-Oct-Unc transcription factors; smart00352
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Gtr1/RagA G protein conserved region; pfam04670
Rag GTPase, subfamily of Ras-related GTPases, includes Ras-related GTP-binding proteins C and D; cd11385
Connexin; pfam00029
Calmodulin-binding; pfam13864
Gap junction channel protein cysteine-rich domain; pfam10582
Rhomboid family; pfam01694
NADH:ubiquinone oxidoreductase, NDUFS5-15kDa; pfam10200
NADH:ubiquinone oxidoreductase, NDUFS5-15kDa; pfam10200
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13833
Growth-Arrest-Specific Protein 2 Domain; smart00243
EspG family; pfam14011
TGF-beta propeptide; pfam00688
Transforming growth factor-beta (TGF-beta) family; smart00204
polyadenylate binding protein, human types 1, 2, 3, 4 family; TIGR01628
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Poly-adenylate binding protein, unique domain; pfam00658
polyadenylate binding protein, human types 1, 2, 3, 4 family; TIGR01628
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Poly-adenylate binding protein, unique domain; pfam00658
polyadenylate binding protein, human types 1, 2, 3, 4 family; TIGR01628
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Poly-adenylate binding protein, unique domain; pfam00658
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Orange domain; smart00511
5'-nucleotidase; pfam06189
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
cyclophilin_ABH_like: Cyclophilin  A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which...; cd01926
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
cyclophilin_ABH_like: Cyclophilin  A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which...; cd01926
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
cyclophilin_ABH_like: Cyclophilin  A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which...; cd01926
TGF-beta propeptide; pfam00688
Transforming growth factor-beta (TGF-beta) family; smart00204
Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; COG1788
Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]
3-oxoacid CoA-transferase, B subunit; TIGR02428
tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; COG0324
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
U1-like zinc finger; smart00451
Myc amino-terminal region; pfam01056
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Myc amino-terminal region; pfam01056
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Myc amino-terminal region; pfam01056
melibiose:sodium symporter; Provisional; cl15392
MFS/sugar transport protein; pfam13347
melibiose:sodium symporter; Provisional; cl15392
MFS/sugar transport protein; pfam13347
Adenylate cyclase associated (CAP) N terminal; pfam01213
Adenylate cyclase associated (CAP) C terminal; pfam08603
Domain in CAPs (cyclase-associated proteins) and X-linked retinitis pigmentosa 2 gene product; smart00673
Domain in CAPs (cyclase-associated proteins) and X-linked retinitis pigmentosa 2 gene product; smart00673
Adenylate cyclase associated (CAP) N terminal; pfam01213
Adenylate cyclase associated (CAP) C terminal; pfam08603
Domain in CAPs (cyclase-associated proteins) and X-linked retinitis pigmentosa 2 gene product; smart00673
Domain in CAPs (cyclase-associated proteins) and X-linked retinitis pigmentosa 2 gene product; smart00673
Palmitoyl protein thioesterase; cl15849
Palmitoyl protein thioesterase; pfam02089
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
Peptidase family M48; pfam01435
Putative GTPase activating protein for Arf; pfam01412
Putative GTPase activating protein for Arf; pfam01412
Putative GTPase activating protein for Arf; pfam01412
Putative GTPase activating protein for Arf; cl02464
SCAN oligomerization domain; cl02605
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cl02605
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Defects in morphology protein 1, mitochondrial precursor; pfam09810
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
C2 domain second repeat contained in Rab3-interacting molecule (RIM) proteins; cd04028
Histone-like transcription factor (CBF/NF-Y) and archaeal histone; pfam00808
Histone-like transcription factor (CBF/NF-Y) and archaeal histone; pfam00808
Histone-like transcription factor (CBF/NF-Y) and archaeal histone; pfam00808
Histone-like transcription factor (CBF/NF-Y) and archaeal histone; pfam00808
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cl00074
Ion transport protein; pfam00520
Ion channel; pfam07885
KCNQ voltage-gated potassium channel; pfam03520
Ion transport protein; pfam00520
Ion channel; pfam07885
KCNQ voltage-gated potassium channel; pfam03520
CITED; pfam04487
CTP synthase
CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; cd03113
Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; cd01746
Divergent AAA domain; pfam04326
Divergent AAA domain; pfam04326
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Protein of unknown function (DUF3588); pfam12140
SAM domain of Scm proteins of Polycomb group; cd09578
Sterile alpha motif; smart00454
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Protein of unknown function (DUF3588); pfam12140
SAM domain of Scm proteins of Polycomb group; cd09578
Sterile alpha motif; smart00454
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Protein of unknown function (DUF3588); pfam12140
SAM domain of Scm proteins of Polycomb group; cd09578
Sterile alpha motif; smart00454
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Protein of unknown function (DUF3588); pfam12140
SAM domain of Scm proteins of Polycomb group; cd09578
Sterile alpha motif; smart00454
mbt repeat; pfam02820
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Protein of unknown function (DUF3588); pfam12140
SAM domain of Scm proteins of Polycomb group; cd09578
Sterile alpha motif; smart00454
mbt repeat; pfam02820
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Protein of unknown function (DUF3588); pfam12140
SAM domain of Scm proteins of Polycomb group; cd09578
Sterile alpha motif; smart00454
mbt repeat; pfam02820
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Protein of unknown function (DUF3588); pfam12140
SAM domain of Scm proteins of Polycomb group; cd09578
Sterile alpha motif; smart00454
Endothelin family; pfam00322
Endothelin; smart00272
Zinc-finger double domain; pfam13465
C2H2-type zinc finger; pfam13912
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
C2H2-type zinc finger; pfam13912
Zinc-finger double domain; pfam13465
Guanylin precursor; pfam02058
Guanylin precursor; pfam02058
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
alpha-L-glutamate ligases, RimK family; TIGR00768
ATP-grasp domain; cl03087
MYND finger; pfam01753
Tetratricopeptide repeat; pfam13424
DNA / pantothenate metabolism flavoprotein; cl04410
DNA / pantothenate metabolism flavoprotein; cl04410
DNA / pantothenate metabolism flavoprotein; cl04410
chromosome segregation protein SMC, common bacterial type; TIGR02168
cyclophilin_ABH_like: Cyclophilin  A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which...; cd01926
peptidyl-prolyl cis-trans isomerase B (rotamase B); Provisional
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
PMP-22/EMP/MP20/Claudin family; cl15797
PMP-22/EMP/MP20/Claudin family; cl15797
PMP-22/EMP/MP20/Claudin family; cl15797
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam13640
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam13640
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam13640
Protein of unknown function (DUF2452); pfam10504
CDP-alcohol phosphatidyltransferase; cl00453
Immunoglobulin domain; cl11960
Immunoglobulin V-Type; smart00406
SPRY-associated domain; pfam13765
Domain in SPla and the RYanodine Receptor; smart00449
Immunoglobulin domain; cl11960
Immunoglobulin V-Type; smart00406
SPRY-associated domain; pfam13765
Domain in SPla and the RYanodine Receptor; smart00449
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
C2H2-type zinc finger; pfam13912
Zinc-finger double domain; pfam13465
Sugar (and other) transporter; pfam00083
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Eukaryotic rRNA processing protein EBP2; pfam05890
Eukaryotic rRNA processing protein EBP2; pfam05890
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Immunoglobulin domain; pfam00047
Laminin-type epidermal growth factor-like domai; smart00180
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Immunoglobulin like; smart00410
Fibronectin type III domain; pfam00041
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Catalytic domain of the Protein Tyrosine Kinase, Tie1; cd05089
Protein kinase; unclassified specificity; smart00221
Immunoglobulin domain; pfam00047
Laminin-type epidermal growth factor-like domai; smart00180
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Immunoglobulin like; smart00410
Fibronectin type III domain; pfam00041
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Catalytic domain of the Protein Tyrosine Kinase, Tie1; cd05089
Protein kinase; unclassified specificity; smart00221
Erythropoietin receptor, ligand binding; pfam09067
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
GNS1/SUR4 family; pfam01151
GNS1/SUR4 family; pfam01151
GNS1/SUR4 family; pfam01151
GNS1/SUR4 family; pfam01151
Mediator of RNA polymerase II transcription complex subunit 8; pfam10232
Mediator of RNA polymerase II transcription complex subunit 8; pfam10232
Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; COG3622
Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; COG3622
Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; COG3622
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Second immunoglobulin (Ig)-like domain of  the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR; cd05738
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR; cd05739
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; smart00060
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Second immunoglobulin (Ig)-like domain of  the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR; cd05738
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR; cd05739
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; smart00060
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Small domain found in the jumonji family of transcription factors; smart00545
JmjC domain, hydroxylase; pfam02373
PHD-finger; pfam13831
PHD-zinc-finger like domain; pfam13832
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cl15348
Tudor domain; smart00333
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
DNA polymerase III subunit alpha; Validated; PRK05673
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Transforming growth factor beta like domain; cl02510
Transforming growth factor beta like domain; cl02510
Transforming growth factor beta like domain; cl02510
Importin beta-related nuclear transport receptor [Nuclear structure / Intracellular trafficking and secretion]; COG5101
Importin-beta N-terminal domain; smart00913
Exportin 1-like protein; pfam08389
diphthamide biosynthesis enzyme Dph1/Dph2 domain; TIGR00322
Putative diphthamide synthesis protein; pfam01866
diphthamide biosynthesis enzyme Dph1/Dph2 domain; cl15477
ATP synthase subunit C; cl00466
ATP synthase subunit C; pfam00137
ATP synthase subunit C; cl00466
ATP synthase subunit C; pfam00137
Beta-4-Galactosyltransferase is involved in the formation of the poly-N-acetyllactosamine core structures present in glycoproteins and glycosphingolipids; cd00899
Beta-4-Galactosyltransferase is involved in the formation of the poly-N-acetyllactosamine core structures present in glycoproteins and glycosphingolipids; cd00899
Beta-4-Galactosyltransferase is involved in the formation of the poly-N-acetyllactosamine core structures present in glycoproteins and glycosphingolipids; cd00899
Na(+)- and Cl(-)-dependent glycine transporter GlyT1; solute-binding domain; cd11498
Na(+)- and Cl(-)-dependent glycine transporter GlyT1; solute-binding domain; cd11498
Na(+)- and Cl(-)-dependent glycine transporter GlyT1; solute-binding domain; cd11498
Na(+)- and Cl(-)-dependent glycine transporter GlyT1; solute-binding domain; cd11498
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
SANT/myb-like domain of Human Dna Methyltransferase 1 Associated Protein 1-like; cd11658
DNA methyltransferase 1-associated protein 1 (DMAP1); pfam05499
SANT/myb-like domain of Human Dna Methyltransferase 1 Associated Protein 1-like; cd11658
DNA methyltransferase 1-associated protein 1 (DMAP1); pfam05499
SANT/myb-like domain of Human Dna Methyltransferase 1 Associated Protein 1-like; cd11658
DNA methyltransferase 1-associated protein 1 (DMAP1); pfam05499
DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins; cd06133
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Eukaryotic protein of unknown function (DUF829); pfam05705
Kinesin motor domain, KIF2-like group. KIF2 is a protein expressed in neurons, which has been associated with axonal transport and neuron development; alternative splice forms have been implicated in lysosomal translocation. This catalytic (head) domain...; cd01367
Kinesin motor, catalytic domain. ATPase; smart00129
Eukaryotic/archaeal ribosomal protein S8e and similar proteins; cd11380
Bestrophin, RFP-TM, chloride channel; pfam01062
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
POLO box duplicated region; pfam00659
POLO box duplicated region; pfam00659
Tctex-1 family; pfam03645
Broad-Complex, Tramtrack and Bric a brac; smart00225
BTB And C-terminal Kelch; cl06652
The Eukaryotic (Putative) Sterol Transporter (EST) Family; TIGR00918
Sterol-sensing domain of SREBP cleavage-activation; pfam12349
The Eukaryotic (Putative) Sterol Transporter (EST) Family; TIGR00918
Sterol-sensing domain of SREBP cleavage-activation; pfam12349
The N-terminal domain of gamma subunit of the eIF-2B is a subfamily of glycosyltransferase 2; cd04198
Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; COG1208
eIF-2B gamma subunit, C-terminal Left-handed parallel beta-Helix (LbH) domain: eIF-2B is a eukaryotic translation initiator, a guanine nucleotide exchange factor (GEF) composed of five different subunits (alpha, beta, gamma, delta and epsilon). eIF2B is...; cd04652
The N-terminal domain of gamma subunit of the eIF-2B is a subfamily of glycosyltransferase 2; cd04198
Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; COG1208
Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; cl00160
The N-terminal domain of gamma subunit of the eIF-2B is a subfamily of glycosyltransferase 2; cd04198
Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; COG1208
Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; cl00160
APC10-like DOC1 domain of HECTD3, a HECT E3 ubiquitin ligase protein that mediates substrate ubiquitination; cd08666
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
HECT-domain (ubiquitin-transferase); pfam00632
methylcobalamin:coenzyme M methyltransferase; Validated
Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; cd00717
4-hydroxyphenylpyruvate dioxygenase; TIGR01263
N-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HPPD) and hydroxymandelate Synthase (HmaS); cd08342
C-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HppD) and hydroxymandelate Synthase (HmaS); cd07250
A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; COG1194
endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; cd00056
iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); smart00525
DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; cd03431
A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; COG1194
endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; cd00056
iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); smart00525
DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; cd03431
A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; COG1194
endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; cd00056
iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); smart00525
DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; cd03431
A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; COG1194
endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; cd00056
iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); smart00525
DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; cd03431
A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; COG1194
endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; cd00056
iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); smart00525
DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; cd03431
A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; COG1194
endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; cd00056
iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); smart00525
DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; cd03431
CAF1 family ribonuclease; pfam04857
Zinc finger C-x8-C-x5-C-x3-H type (and similar); cl11592
Tyrosine kinase, catalytic domain; smart00219
Catalytic domain of Protein Kinases; cd00180
tryparedoxin peroxidase; Provisional
Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; cd03015
tryparedoxin peroxidase; Provisional
Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; cd03015
tryparedoxin peroxidase; Provisional
Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; cd03015
tryparedoxin peroxidase; Provisional
Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; cd03015
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Aldo/keto reductase family; pfam00248
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Aldo/keto reductase family; pfam00248
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Aldo/keto reductase family; pfam00248
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Aldo/keto reductase family; pfam00248
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Protein of unknown function (DUF3429); pfam11911
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch domain; smart00612
Kelch domain; smart00612
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch domain; smart00612
Kelch domain; smart00612
Kelch motif; pfam01344
Domain of unknown function (DUF1908); pfam08926
Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase; cd05609
Serine/Threonine protein kinases, catalytic domain; smart00220
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
N-terminal Src homology 2 (nSH2) domain found in p85; cd09942
C-terminal Src homology 2 (cSH2) domain found in p85; cd09930
N-terminal Src homology 2 (nSH2) domain found in p85; cd09942
C-terminal Src homology 2 (cSH2) domain found in p85; cd09930
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), uroplakin_I_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment...; cd03156
GT13_GLCNAC-TI is involved in an essential step in the synthesis of complex or hybrid-type N-linked oligosaccharides; cd02514
GT13_GLCNAC-TI is involved in an essential step in the synthesis of complex or hybrid-type N-linked oligosaccharides; cd02514
Rad54 N terminal; pfam08658
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Rad54 N terminal; pfam08658
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Ubiquinol-cytochrome C reductase hinge protein; pfam02320
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; COG0154
Amidase; pfam01425
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
OAR domain; pfam03826
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
OAR domain; pfam03826
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Mob1/phocein family; pfam03637
Mob1/phocein family; pfam03637
ATP11 protein; pfam06644
ATP11 protein; pfam06644
ATP11 protein; pfam06644
ATP11 protein; pfam06644
ATP11 protein; pfam06644
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; COG2124
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; COG2124
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; COG2124
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; COG2124
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; COG2124
Cytochrome P450; pfam00067
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; COG2124
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
The use of an alternate start codon is shown in PMID:11912132.
UMP-CMP kinase family; TIGR01359
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; cd01428
The use of an alternate start codon is shown in PMID:11912132.
UMP-CMP kinase family; TIGR01359
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; cd01428
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
TraB family; pfam01963
Na(+)/glucose cotransporter SGLT4 and related proteins; solute-binding domain; cd11488
Na(+)/glucose cotransporter SGLT4 and related proteins; solute-binding domain; cd11488
Predicted carboxypeptidase [Amino acid transport and metabolism]
Peptidase M14-like domain of ATP/GTP binding protein AGBL-4 and related proteins; cd06908
The BEN domain is found in diverse animal proteins; smart01025
ELAV/HuD family splicing factor; TIGR01661
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
ELAV/HuD family splicing factor; TIGR01661
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
ELAV/HuD family splicing factor; TIGR01661
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
ELAV/HuD family splicing factor; TIGR01661
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
ELAV/HuD family splicing factor; TIGR01661
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
DM DNA binding domain; pfam00751
DMRTA motif; pfam03474
UAS family, FAS-associated factor 1 (FAF1) subfamily; FAF1 contains a UAS domain of unknown function N-terminal to a ubiquitin-associated UBX domain. FAF1 also contains ubiquitin-associated UBA and nuclear targeting domains, N-terminal to the UAS domain; cd02990
Faf1 UBX domain; cd01771
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
Ankyrin repeats (3 copies); pfam12796
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Protein of unknown function (DUF3808); pfam10300
Protein of unknown function (DUF3808); pfam10300
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
TPR/MLP1/MLP2-like protein; pfam07926
TATA element modulatory factor 1 TATA binding; pfam12325
TPR/MLP1/MLP2-like protein; pfam07926
TATA element modulatory factor 1 TATA binding; pfam12325
Oxysterol binding protein (OSBP) Pleckstrin homology (PH) domain; cd01246
Oxysterol-binding protein; pfam01237
Oxysterol binding protein (OSBP) Pleckstrin homology (PH) domain; cd01246
Oxysterol-binding protein; pfam01237
Oxysterol binding protein (OSBP) Pleckstrin homology (PH) domain; cd01246
Oxysterol-binding protein; pfam01237
Oxysterol binding protein (OSBP) Pleckstrin homology (PH) domain; cd01246
Oxysterol-binding protein; pfam01237
Oxysterol-binding protein; pfam01237
Oxysterol-binding protein; pfam01237
Oxysterol-binding protein; pfam01237
Insulinase (Peptidase family M16); pfam00675
Secreted/periplasmic Zn-dependent peptidases, insulinase-like [Posttranslational modification, protein turnover, chaperones]; COG1025
Peptidase M16 inactive domain; pfam05193
Peptidase M16 inactive domain; pfam05193
Insulinase (Peptidase family M16); pfam00675
Secreted/periplasmic Zn-dependent peptidases, insulinase-like [Posttranslational modification, protein turnover, chaperones]; COG1025
Peptidase M16 inactive domain; pfam05193
Peptidase M16 inactive domain; pfam05193
Secreted/periplasmic Zn-dependent peptidases, insulinase-like [Posttranslational modification, protein turnover, chaperones]; COG1025
Insulinase (Peptidase family M16); pfam00675
Peptidase M16 inactive domain; pfam05193
Peptidase M16 inactive domain; pfam05193
GTPase SAR1 and related small G proteins [General function prediction only]
Rab GTPase family 3 contains Rab3A, Rab3B, Rab3C and Rab3D; cd01865
Endoplasmic reticulum protein 19 (ERp19) family; ERp19 is also known as ERp18, a protein located in the ER containing one redox active TRX domain. Denaturation studies indicate that the reduced form is more stable than the oxidized form, suggesting that...; cd02959
Chromatin associated protein KTI12; pfam08433
NAC domain; pfam01849
NAC domain; pfam01849
FYVE zinc finger; pfam01363
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Smad anchor for receptor activation (SARA); pfam11409
Domain of unknown function (DUF3480); pfam11979
FYVE zinc finger; pfam01363
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Domain of unknown function (DUF3480); pfam11979
FYVE zinc finger; pfam01363
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Repeats in fly CG4713, worm Y37H9A.3 and human FLJ20241; smart00685
Repeats in fly CG4713, worm Y37H9A.3 and human FLJ20241; smart00685
Repeats in fly CG4713, worm Y37H9A.3 and human FLJ20241; smart00685
Repeats in fly CG4713, worm Y37H9A.3 and human FLJ20241; smart00685
C2 domain found in 5' repressor element under dual repression binding protein-1 (Freud-1); cd08690
BAH, or Bromo Adjacent Homology domain, as present in animal homologs of Saccharomyces cerevisiae Orc1p. Orc1 is part of the Yeast Sir1-origin recognition complex. The Orc1p BAH doman functions in epigenetic silencing. In vertebrates, a similar ORC...; cd04719
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Winged-helix domain of essential DNA replication protein Cell division control protein (Cdc6), which mediates DNA binding; cd08768
BAH, or Bromo Adjacent Homology domain, as present in animal homologs of Saccharomyces cerevisiae Orc1p. Orc1 is part of the Yeast Sir1-origin recognition complex. The Orc1p BAH doman functions in epigenetic silencing. In vertebrates, a similar ORC...; cd04719
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Winged-helix domain of essential DNA replication protein Cell division control protein (Cdc6), which mediates DNA binding; cd08768
BAH, or Bromo Adjacent Homology domain, as present in animal homologs of Saccharomyces cerevisiae Orc1p. Orc1 is part of the Yeast Sir1-origin recognition complex. The Orc1p BAH doman functions in epigenetic silencing. In vertebrates, a similar ORC...; cd04719
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Winged-helix domain of essential DNA replication protein Cell division control protein (Cdc6), which mediates DNA binding; cd08768
PRP38 family; pfam03371
Ribosomal protein L4/L1 family; cl00325
Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases; cd05402
Cid1 family poly A polymerase; pfam03828
Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases; cd05402
Cid1 family poly A polymerase; pfam03828
universal minicircle sequence binding protein (UMSBP); Provisional
Zinc knuckle; pfam00098
Ribosomal protein L4/L1 family; cl00325
Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases; cd05402
Cid1 family poly A polymerase; pfam03828
Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases; cd05402
Cid1 family poly A polymerase; pfam03828
Zinc knuckle; pfam00098
Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; cd00340
Wnt and FGF inhibitory regulator; pfam13908
FOG: TPR repeat, SEL1 subfamily [General function prediction only]
Sel1 repeat; cl02723
Leucine Rich repeats (2 copies); pfam12799
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Leucine Rich repeats (2 copies); pfam12799
Protein Kinases, catalytic domain; cl09925
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
enoyl-CoA hydratase
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; cd06558
enoyl-CoA hydratase
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; cd06558
enoyl-CoA hydratase
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; cd06558
lipid-transfer protein; Provisional
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2...; cd00826
SCP-2 sterol transfer family; pfam02036
lipid-transfer protein; Provisional
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2...; cd00826
SCP-2 sterol transfer family; pfam02036
lipid-transfer protein; Provisional
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2...; cd00826
SCP-2 sterol transfer family; pfam02036
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2...; cd00826
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2...; cd00826
SCP-2 sterol transfer family; pfam02036
SCP-2 sterol transfer family; pfam02036
SCP-2 sterol transfer family; pfam02036
Leucine rich repeat N-terminal domain; smart00013
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat N-terminal domain; smart00013
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat N-terminal domain; smart00013
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat N-terminal domain; smart00013
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Sodium:dicarboxylate symporter family; cl00573
Na+/H+-dicarboxylate symporters [Energy production and conversion]; COG1301
Sodium:dicarboxylate symporter family; pfam00375
Na+/H+-dicarboxylate symporters [Energy production and conversion]; COG1301
Choline/Carnitine o-acyltransferase; pfam00755
Eukaryotic protein of unknown function (DUF866); pfam05907
Mago nashi proteins, integral members of the exon junction complex; cd11295
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Low-density lipoprotein receptor repeat class B; cl10508
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Low-density lipoprotein receptor repeat class B; cl10508
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Low-density lipoprotein receptor repeat class B; cl10508
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Low-density lipoprotein receptor repeat class B; cl10508
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
DM DNA binding domain; pfam00751
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Nucleoporin protein Ndc1-Nup; pfam09531
Nucleoporin protein Ndc1-Nup; pfam09531
Nucleoporin protein Ndc1-Nup; pfam09531
Nucleoporin protein Ndc1-Nup; pfam09531
Yip1 domain; pfam04893
Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; cl00388
Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; cl00388
Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; cl00388
Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; cl00388
F5/8 type C domain; pfam00754
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine Rich repeats (2 copies); pfam12799
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine Rich repeats (2 copies); pfam12799
Brain specific membrane anchored protein; pfam12280
N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme; cd00183
Transcription factor S-II (TFIIS), central domain; cl02637
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
NADH-cytochrome B5 reductase; Provisional
Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a...; cd06183
Mitochondrial 28S ribosomal protein S30 (PDCD9); pfam07147
Single-stranded DNA binding protein, SSDP; pfam04503
Single-stranded DNA binding protein, SSDP; pfam04503
Single-stranded DNA binding protein, SSDP; pfam04503
Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; cd03442
Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; cd03442
Lipid-binding START domain of mammalian STARDT14 and related proteins; cd08913
Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; cd03442
Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; cd03442
Lipid-binding START domain of mammalian STARDT14 and related proteins; cd08913
Uncharacterized conserved protein (DUF2181); pfam10223
Uncharacterized conserved protein (DUF2181); pfam10223
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
prolyl-tRNA synthetase; Provisional
Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of...; cd00779
ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; cd00861
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
FAD binding domain; pfam01565
FAD/FMN-containing dehydrogenases [Energy production and conversion]; COG0277
Peptidase inhibitor I9; pfam05922
Peptidase S8 family domain in ProteinaseK-like proteins; cd04077
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02659
Ubiquitin carboxyl-terminal hydrolase; pfam00443
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Src Homology 3 domain superfamily; cl17036
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
membrane-attack complex / perforin; smart00457
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
membrane-attack complex / perforin; smart00457
Thrombospondin type 1 repeats; smart00209
Disabled (Dab) Phosphotyrosine-binding domain; cd01215
Peptidase family M48; pfam01435
Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases; cd00191
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
SWIRM domain; pfam04433
Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase; cd08067
Jun-like transcription factor; pfam03957
bZIP transcription factor; pfam00170
Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases; cd07782
FGGY-family pentulose kinase; TIGR01315
Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases; cd07782
FGGY-family pentulose kinase; TIGR01315
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cl17037
Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases; cd07782
HOOK protein; pfam05622
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Nuclear factor I protein pre-N-terminus; pfam10524
MH1 domain; pfam03165
CTF/NF-I family transcription modulation region; pfam00859
Nuclear factor I protein pre-N-terminus; pfam10524
N-terminal Mad Homology 1 (MH1) domain; cl00055
CTF/NF-I family transcription modulation region; pfam00859
Nuclear factor I protein pre-N-terminus; pfam10524
N-terminal Mad Homology 1 (MH1) domain; cl00055
CTF/NF-I family transcription modulation region; pfam00859
Nuclear factor I protein pre-N-terminus; pfam10524
N-terminal Mad Homology 1 (MH1) domain; cl00055
CTF/NF-I family transcription modulation region; pfam00859
TM2 domain; pfam05154
L27_2; pfam09045
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
L1 transposable element; pfam02994
L1 transposable element; pfam02994
KN motif; pfam12075
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13637
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02671
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02671
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02671
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Domain of unknown function (DUF3398); pfam11878
C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins; cd08696
Dock Homology Region 2, a GEF domain, of Class C Dedicator of Cytokinesis 7; cd11703
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
Peptidase family C54; pfam03416
Peptidase family C54; pfam03416
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
ALG6, ALG8 glycosyltransferase family; pfam03155
Nuclear receptor co-activator NRIF3; pfam06729
Putative binding domain; pfam13900
Nuclear receptor co-activator NRIF3; pfam06729
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
phosphoglucomutase
Phosphoglucomutase 1 (PGM1) catalyzes the bidirectional interconversion of glucose-1-phosphate (G-1-P) and glucose-6-phosphate (G-6-P) via a glucose 1,6-diphosphate intermediate, an important metabolic step in prokaryotes and eukaryotes. In one direction; cd03085
Phosphoglucomutase 1 (PGM1) catalyzes the bidirectional interconversion of glucose-1-phosphate (G-1-P) and glucose-6-phosphate (G-6-P) via a glucose 1,6-diphosphate intermediate, an important metabolic step in prokaryotes and eukaryotes. In one direction; cd03085
phosphoglucomutase
The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; cl03757
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Cysteine-rich domain of tyrosine kinase-like orphan receptor 1; cd07467
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and...; cd00108
Catalytic domain of the Protein Tyrosine Kinase, Receptor tyrosine kinase-like Orphan Receptor 1; cd05090
Protein tyrosine kinase; pfam07714
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Cysteine-rich domain of tyrosine kinase-like orphan receptor 1; cd07467
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and...; cd00108
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
VWA N-terminal; pfam08399
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Cache domain; pfam02743
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Band 4.1 homologues; smart00295
Src homology 2 (SH2) domain in the Janus kinase 1 (Jak1) proteins; cd10378
Protein tyrosine kinase; pfam07714
Pseudokinase (repeat 1) domain of the Protein Tyrosine Kinase, Janus kinase 1; cd05077
Catalytic (repeat 2) domain of the Protein Tyrosine Kinase, Janus kinase 1; cd05079
Protein tyrosine kinase; pfam07714
adenylate kinases; TIGR01351
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; cd01428
adenylate kinases; TIGR01351
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; cd01428
adenylate kinases; TIGR01351
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; cd01428
C2 domain of PTEN tumour-suppressor protein; pfam10409
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
C2 domain of PTEN tumour-suppressor protein; pfam10409
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
C2 domain of PTEN tumour-suppressor protein; pfam10409
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
Vacuolar protein sorting 55; pfam04133
Vacuolar protein sorting 55; pfam04133
Vacuolar protein sorting 55; pfam04133
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Ig-like C2-type domain; pfam06328
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Ig-like C2-type domain; pfam06328
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Ig-like C2-type domain; pfam06328
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Ig-like C2-type domain; pfam06328
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Ig-like C2-type domain; pfam06328
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Ig-like C2-type domain; pfam06328
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cl00065
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
mu-homology domain (MHD) of Scr homology 3 (SH3)-domain growth factor receptor-bound 2 (GRB2)-like (endophilin) interacting protein 1 (also known as endophilin-3-interacting protein, SGIP1) and similar proteins; cd09266
Tctex-1 family; pfam03645
IlGF_like family, relaxin_like subgroup, specific to vertebrates. Members include a number of active peptides including (pro)relaxin, mammalian Leydig cell-specific insulin-like peptide (gene INSL3), early placenta insulin-like peptide (ELIP; gene INSL4); cd04365
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
ELM2 domain; pfam01448
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
Myb-Like Dna-Binding Domain of MTA3 and related proteins; cd11661
ELM2 domain; pfam01448
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
Myb-Like Dna-Binding Domain of MTA3 and related proteins; cd11661
ELM2 domain; pfam01448
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
Myb-Like Dna-Binding Domain of MTA3 and related proteins; cd11661
ELM2 domain; pfam01448
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
Myb-Like Dna-Binding Domain of MTA3 and related proteins; cd11661
ELM2 domain; pfam01448
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
Myb-Like Dna-Binding Domain of MTA3 and related proteins; cd11661
ELM2 domain; pfam01448
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
Myb-Like Dna-Binding Domain of MTA3 and related proteins; cd11661
ELM2 domain; pfam01448
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
Myb-Like Dna-Binding Domain of MTA3 and related proteins; cd11661
ELM2 domain; pfam01448
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
Myb-Like Dna-Binding Domain of MTA3 and related proteins; cd11661
ELM2 domain; pfam01448
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
Myb-Like Dna-Binding Domain of MTA3 and related proteins; cd11661
ELM2 domain; pfam01448
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
Myb-Like Dna-Binding Domain of MTA3 and related proteins; cd11661
Nucleotide-sugar transporter [Carbohydrate transport and metabolism / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; COG5070
EamA-like transporter family; cl01037
Interleukin-6 receptor alpha chain, binding; cl12153
Ig-like C2-type domain; pfam06328
Interleukin-6 receptor alpha chain, binding; cl12153
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Ig-like C2-type domain; pfam06328
Interleukin-6 receptor alpha chain, binding; cl12153
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Ig-like C2-type domain; pfam06328
Interleukin-6 receptor alpha chain, binding; cl12153
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Ig-like C2-type domain; pfam06328
Interleukin-6 receptor alpha chain, binding; cl12153
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Hyaluronan / mRNA binding family; pfam04774
Hyaluronan / mRNA binding family; pfam04774
Hyaluronan / mRNA binding family; pfam04774
Hyaluronan / mRNA binding family; pfam04774
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; pfam01248
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors; cd00068
GTPase SAR1 and related small G proteins [General function prediction only]
A Ras homolog member I (ARHI); cd04140
Wnt-binding factor required for Wnt secretion; pfam06664
Wnt-binding factor required for Wnt secretion; pfam06664
Wnt-binding factor required for Wnt secretion; pfam06664
Retinal pigment epithelial membrane protein; pfam03055
Lignostilbene-alpha,beta-dioxygenase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]
DEP domain, named after Dishevelled, Egl-10, and Pleckstrin, where this domain was first discovered. The function of this domain is still not clear, but it is believed to be important for the membrane association of the signaling proteins in which it is...; cl02442
RhoGAP_BRCC3-like: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of BRCC3-like proteins. This subgroup also contains two groups of closely related proteins, BRCC3 and DEPDC7, which both contain a C-terminal RhoGAP-like domain...; cd04405
DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in BBRC3-like proteins. BBRC3, also known as DEPDC1B, is a DEP containing protein of unknown function; cd04447
RhoGAP_BRCC3-like: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of BRCC3-like proteins. This subgroup also contains two groups of closely related proteins, BRCC3 and DEPDC7, which both contain a C-terminal RhoGAP-like domain...; cd04405
RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when...; cl02570
RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when...; cl02570
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
Ankyrin repeats (many copies); pfam13637
GPCR-chaperone; pfam11904
Cys/Met metabolism PLP-dependent enzyme; pfam01053
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; cd00614
Cys/Met metabolism PLP-dependent enzyme; pfam01053
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; cd00614
Cys/Met metabolism PLP-dependent enzyme; pfam01053
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; cd00614
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
Zinc finger domain; smart00547
Zinc finger domain; smart00547
Zinc finger domain; smart00547
Zinc finger domain; smart00547
Immunoglobulin like; smart00410
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Leucine rich repeat; pfam13855
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
Protein tyrosine kinase; pfam07714
Protein Kinases, catalytic domain; cl09925
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
Protein tyrosine kinase; pfam07714
Protein Kinases, catalytic domain; cl09925
L-fucokinase; pfam07959
Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; cl00160
Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; cl00160
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
Protein tyrosine kinase; pfam07714
Protein Kinases, catalytic domain; cl09925
Zeta-crystallin with NADP-dependent quinone reductase activity (QOR); cd08253
NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; COG0604
Zeta-crystallin with NADP-dependent quinone reductase activity (QOR); cd08253
NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; COG0604
Zeta-crystallin with NADP-dependent quinone reductase activity (QOR); cd08253
NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; COG0604
Zeta-crystallin with NADP-dependent quinone reductase activity (QOR); cd08253
NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; COG0604
Methyltransferase TYW3; pfam02676
Methyltransferase TYW3; pfam02676
The first LIM domain of Lhx7 and Lhx8; cd09381
The second LIM domain of Lhx7 and Lhx8; cd09383
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
The first LIM domain of Lhx7 and Lhx8; cd09381
The second LIM domain of Lhx7 and Lhx8; cd09383
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Plasma-membrane choline transporter; pfam04515
Plasma-membrane choline transporter; pfam04515
Acyl-CoA dehydrogenases [Lipid metabolism]; COG1960
Medium chain acyl-CoA dehydrogenase; cd01157
Acyl-CoA dehydrogenases [Lipid metabolism]; COG1960
Medium chain acyl-CoA dehydrogenase; cd01157
RAB geranylgeranyl transferase beta-subunit; Provisional
Geranylgeranyltransferase type II (GGTase-II)_like proteins containing the protein prenyltransferase (PTase) domain, beta subunit (alpha 6 - alpha 6 barrel fold). GGTase-IIs are a subgroup of the protein prenyltransferase family of lipid-modifying...; cd02894
MutS domain II; pfam05188
MutS domain III; pfam05192
MutS family domain IV; pfam05190
MutS domain V; pfam00488
Ankyrin repeats (3 copies); pfam12796
SOCS (suppressors of cytokine signaling) box of ASB (ankyrin repeat and SOCS box) and SSB (SPRY domain-containing SOCS box proteins) protein families. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence of a variable...; cd03716
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Peptidase C13 family; cl02159
adenylate kinase, isozyme 1 subfamily; TIGR01360
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; cd01428
adenylate kinase, isozyme 1 subfamily; TIGR01360
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; cd01428
adenylate kinase, isozyme 1 subfamily; TIGR01360
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; cd01428
adenylate kinase, isozyme 1 subfamily; TIGR01360
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; cd01428
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
Zinc finger, ZZ type. Zinc finger present in ZZZ3 (ZZ finger containing 3) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding; cd02341
Zn-finger in ubiquitin-hydrolases and other protein; pfam02148
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02674
Domain in ubiquitin-specific proteases; smart00695
Domain in ubiquitin-specific proteases; smart00695
Zn-finger in ubiquitin-hydrolases and other protein; pfam02148
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02674
Domain in ubiquitin-specific proteases; smart00695
Domain in ubiquitin-specific proteases; smart00695
Zn-finger in ubiquitin-hydrolases and other protein; pfam02148
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02674
Domain in ubiquitin-specific proteases; smart00695
Uncharacterized conserved protein (DUF2217); pfam10265
Uncharacterized conserved protein (DUF2217); pfam10265
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
KH-II  (K homology RNA-binding domain, type II). KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins  (e.g. ribosomal protein S3), transcription factors (e.g. NusA_K), and post-transcriptional...; cl00098
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]; COG0484
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
C-terminal substrate binding domain of DnaJ and HSP40; cd10747
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); cd00882
TLD; cl02144
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Domain of unknown function (DUF3497); pfam12003
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); pfam00002
Galactose binding lectin domain; pfam02140
Olfactomedin-like domain; pfam02191
Domain present in hormone receptors; smart00008
Domain of unknown function (DUF3497); pfam12003
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
Latrophilin Cytoplasmic C-terminal region; pfam02354
Tubulin-tyrosine ligase family; pfam03133
protein kinase A catalytic subunit; Provisional
Catalytic domain of the Protein Serine/Threonine Kinase, cAMP-dependent protein kinase; cd05580
Catalytic domain of the Protein Serine/Threonine Kinase, cAMP-dependent protein kinase; cd05580
protein kinase A catalytic subunit; Provisional
Catalytic domain of the Protein Serine/Threonine Kinase, cAMP-dependent protein kinase; cd05580
protein kinase A catalytic subunit; Provisional
Catalytic domain of the Protein Serine/Threonine Kinase, cAMP-dependent protein kinase; cd05580
protein kinase A catalytic subunit; Provisional
Catalytic domain of the Protein Serine/Threonine Kinase, cAMP-dependent protein kinase; cd05580
protein kinase A catalytic subunit; Provisional
Catalytic domain of the Protein Serine/Threonine Kinase, cAMP-dependent protein kinase; cd05580
protein kinase A catalytic subunit; Provisional
Catalytic domain of the Protein Serine/Threonine Kinase, cAMP-dependent protein kinase; cd05580
protein kinase A catalytic subunit; Provisional
Catalytic domain of the Protein Serine/Threonine Kinase, cAMP-dependent protein kinase; cd05580
protein kinase A catalytic subunit; Provisional
Catalytic domain of the Protein Serine/Threonine Kinase, cAMP-dependent protein kinase; cd05580
SAM domain of Atherin/Atherin-like subfamily; cd09583
SAM domain of Atherin/Atherin-like subfamily; cd09583
SAM domain of Atherin/Atherin-like subfamily; cd09583
Catalytic domain, repeat 1, of Deoxyribonuclease II beta and similar proteins; cd09190
Deoxyribonuclease II; pfam03265
Catalytic domain, repeat 2, of Deoxyribonuclease II beta and similar proteins; cd09192
Catalytic domain, repeat 2, of Deoxyribonuclease II beta and similar proteins; cd09192
The Brix domain is found in a number of eukaryotic proteins; smart00879
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors; cd00068
Chitobiase (also known as di-N-acetylchitobiase) is a lysosomal glycosidase that hydrolyzes the reducing-end N-acetylglucosamine from the chitobiose core of oligosaccharides during the ordered degradation of asparagine-linked glycoproteins in eukaryotes; cd02875
Glyco_18 domain; smart00636
Afadin- and alpha -actinin-Binding; pfam11559
Afadin- and alpha -actinin-Binding; pfam11559
Afadin- and alpha -actinin-Binding; pfam11559
Afadin- and alpha -actinin-Binding; pfam11559
Afadin- and alpha -actinin-Binding; pfam11559
7 transmembrane receptor (rhodopsin family); pfam00001
Polycystin cation channel; pfam08016
Polycystin cation channel; pfam08016
Polycystin cation channel; pfam08016
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
C2 domain; cl14603
RhoGAP_SYD1: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in SYD-1_like proteins. Syd-1, first identified and best studied in C.elegans, has been shown to play an important role in neuronal development by specifying...; cd04379
GTPase-activator protein for Rho-like GTPases; smart00324
Caspase activation and recruitment domain of B-cell lymphoma 10; cd08810
Amidinotransferase; pfam02274
Amidinotransferase; cl12043
Insulin-like growth factor binding protein; pfam00219
von Willebrand factor type C domain; cl02515
Thrombospondin type 1 domain; cl15278
Glycoprotein hormone beta chain homologues; cl00070
HIT zinc finger; pfam04438
HIT zinc finger; pfam04438
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cl00102
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Fibrillar collagen C-terminal domain; cl02436
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
Calcium-activated chloride channel; pfam08434
calcium-activated chloride channel protein 1; TIGR00868
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cd00198
Domain of unknown function (DUF1973); pfam09315
calcium-activated chloride channel protein 1; TIGR00868
Calcium-activated chloride channel; pfam08434
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cd00198
Domain of unknown function (DUF1973); pfam09315
calcium-activated chloride channel protein 1; TIGR00868
Calcium-activated chloride channel; pfam08434
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cd00198
Domain of unknown function (DUF1973); pfam09315
BAR domain; smart00721
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; cl12013
Src homology 3 domain of Endophilin-B1; cd11945
BAR domain; smart00721
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; cl12013
Src homology 3 domain of Endophilin-B1; cd11945
BAR domain; smart00721
The Bin/Amphiphysin/Rvs (BAR) domain of Endophilin-B1; cd07616
Src homology 3 domain of Endophilin-B1; cd11945
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; cl12013
BAR domain; smart00721
Src homology 3 domain of Endophilin-B1; cd11945
Sep15/SelM redox domain; pfam08806
Sep15/SelM redox domain; pfam08806
Sulfotransferase family; pfam03567
Sulfotransferase family; pfam03567
The first LIM domain of LMO4 (LIM domain only protein 4); cd09386
The second LIM domain of LMO4 (LIM domain only protein 4); cd09387
First Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N; cd11622
Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N2; cd11631
Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N2; cd11635
C2 domain in Protein kinase C-like (PKN) proteins; cd08687
Catalytic domain of the Protein Serine/Threonine Kinase, Protein Kinase N; cd05589
Serine/Threonine protein kinases, catalytic domain; smart00220
Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB [Transcription]; COG1405
TFIIB zinc-binding; pfam08271
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
hypothetical protein; Provisional
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; cd00609
hypothetical protein; Provisional
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; cd00609
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RBM1CTR (NUC064) family; pfam08081
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RBM1CTR (NUC064) family; pfam08081
Guanylate-binding protein (GBP) family (N-terminal domain); cd01851
Guanylate-binding protein, C-terminal domain; pfam02841
Guanylate-binding protein (GBP) family (N-terminal domain); cd01851
Guanylate-binding protein, C-terminal domain; pfam02841
Guanylate-binding protein (GBP) family (N-terminal domain); cd01851
Guanylate-binding protein, C-terminal domain; pfam02841
Guanylate-binding protein (GBP) family (N-terminal domain); cd01851
Guanylate-binding protein, C-terminal domain; pfam02841
Guanylate-binding protein (GBP) family (N-terminal domain); cd01851
Guanylate-binding protein, C-terminal domain; pfam02841
Guanylate-binding protein (GBP) family (N-terminal domain); cd01851
Guanylate-binding protein, C-terminal domain; pfam02841
Guanylate-binding protein (GBP) family (N-terminal domain); cd01851
Guanylate-binding protein, C-terminal domain; pfam02841
Guanylate-binding protein (GBP) family (N-terminal domain); cd01851
Guanylate-binding protein, C-terminal domain; pfam02841
Leucine-rich repeat containing protein 8; pfam12534
Leucine-rich repeat containing protein 8; pfam12534
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeat containing protein 8; pfam12534
Leucine-rich repeat containing protein 8; pfam12534
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeat containing protein 8; pfam12534
Leucine-rich repeat containing protein 8; pfam12534
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeat containing protein 8; pfam12534
Leucine-rich repeat containing protein 8; pfam12534
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeat containing protein 8; pfam12534
Leucine-rich repeat containing protein 8; pfam12534
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
A-kinase anchoring protein 95 (AKAP95); pfam04988
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Zinc finger, C2H2 type; cl15478
Superfamily II helicase [General function prediction only]
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Sec63 Brl domain; smart00973
Catalytic domain of Protein Kinases; cd00180
Protein Kinases, catalytic domain; cl09925
Protein Kinases, catalytic domain; cl09925
Catalytic domain of Protein Kinases; cd00180
Protein Kinases, catalytic domain; cl09925
Protein Kinases, catalytic domain; cl09925
Catalytic domain of Protein Kinases; cd00180
Protein Kinases, catalytic domain; cl09925
Protein Kinases, catalytic domain; cl09925
Zona pellucida (ZP) domain; smart00241
Zona pellucida (ZP) domain; smart00241
Zona pellucida (ZP) domain; smart00241
Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino...; cd05497
Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino...; cd05498
Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino...; cd05497
Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino...; cd05498
Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino...; cd05497
Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino...; cd05498
Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino...; cd05497
Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino...; cd05498
Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine; cl02556
Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino...; cd05498
Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine; cl02556
Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino...; cd05498
Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine; cl02556
Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino...; cd05498
Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; COG0596
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
BTB/POZ domain; cl02518
Broad-Complex, Tramtrack and Bric a brac; smart00225
Uncharacterized protein family, YAP/Alf4/glomulin; pfam08568
Rtr1/RPAP2 family; pfam04181
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
Protein of unknown function (DUF1129); cl11555
60S ribosomal protein L5; Provisional
Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; cd00432
Ribosomal L18 C-terminal region; pfam14204
Pancreatitis induced protein 49 C terminal; pfam12260
Pancreatitis induced protein 49 C terminal; pfam12260
Pancreatitis induced protein 49 C terminal; pfam12260
Pancreatitis induced protein 49 C terminal; pfam12260
Tudor domain; smart00333
PHD-finger; pfam00628
PHD zinc finger; smart00249
Polycomb-like MTF2 factor 2; pfam14061
Tudor domain; smart00333
PHD-finger; pfam00628
PHD zinc finger; smart00249
Polycomb-like MTF2 factor 2; pfam14061
PHD-finger; pfam00628
PHD zinc finger; smart00249
Polycomb-like MTF2 factor 2; pfam14061
PHD-finger; pfam00628
PHD zinc finger; smart00249
Polycomb-like MTF2 factor 2; pfam14061
emp24/gp25L/p24 family/GOLD; pfam01105
emp24/gp25L/p24 family/GOLD; pfam01105
chromosome segregation protein SMC, common bacterial type; TIGR02168
V-type ATPase 116kDa subunit family; pfam01496
chromosome segregation protein SMC, common bacterial type; TIGR02168
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cl00074
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Formin Binding Protein 1-Like; cd07675
Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of vertebrate Cdc42-Interacting Protein 4 and FormiN Binding Protein 1-Like; cd11628
Src Homology 3 domain of Formin Binding Protein 1-Like; cd12072
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Formin Binding Protein 1-Like; cd07675
Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of vertebrate Cdc42-Interacting Protein 4 and FormiN Binding Protein 1-Like; cd11628
Src Homology 3 domain of Formin Binding Protein 1-Like; cd12072
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Formin Binding Protein 1-Like; cd07675
Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of vertebrate Cdc42-Interacting Protein 4 and FormiN Binding Protein 1-Like; cd11628
Src Homology 3 domain of Formin Binding Protein 1-Like; cd12072
Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3; cd10337
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3; cd10337
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3; cd10337
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3; cd10337
Guanine nucleotide exchange factor for Ras-like small GTPases; smart00147
Fcf2 pre-rRNA processing; pfam08698
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cl00470
retinal-specific rim ABC transporter; TIGR01257
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; cl12013
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
RhoGAP_PARG1: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of PARG1 (PTPL1-associated RhoGAP1). PARG1 was originally cloned as an interaction partner of PTPL1, an intracellular protein-tyrosine phosphatase. PARG1 interacts...; cd04409
GTPase-activator protein for Rho-like GTPases; smart00324
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protei; TIGR00954
ABC transporter transmembrane region 2; pfam06472
Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome.  The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed...; cd03223
ABC transporter transmembrane region; cl00549
Tissue factor; pfam01108
Interferon-alpha/beta receptor, fibronectin type III; pfam09294
Tissue factor; pfam01108
Interferon-alpha/beta receptor, fibronectin type III; pfam09294
Plasma-membrane choline transporter; pfam04515
Plasma-membrane choline transporter; pfam04515
Plasma-membrane choline transporter; pfam04515
Plasma-membrane choline transporter; pfam04515
Plasma-membrane choline transporter; pfam04515
Plasma-membrane choline transporter; pfam04515
Calponin [Cytoskeleton]; COG5199
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin family repeat; pfam00402
Calponin family repeat; pfam00402
Calponin family repeat; pfam00402
Oligosaccharide biosynthesis protein Alg14 like; pfam08660
TRAM, LAG1 and CLN8 homology domains; smart00724
TRAM, LAG1 and CLN8 homology domains; smart00724
TRAM, LAG1 and CLN8 homology domains; smart00724
RWD domain; pfam05773
RWD domain; pfam05773
RWD domain; pfam05773
hnRNP-L/PTB/hephaestus splicing factor family; TIGR01649
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
dihydropyrimidine dehydrogenase subunit A; Provisional
NAD(P)-binding Rossmann-like domain; pfam13450
Dihydroorotate dehydrogenase [Nucleotide transport and metabolism]; COG0167
Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; cd02940
4Fe-4S dicluster domain; pfam13237
dihydropyrimidine dehydrogenase subunit A; Provisional
The phosphoinositide binding Phox Homology domain of Sorting Nexin 7; cd07284
The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 7; cd07666
The phosphoinositide binding Phox Homology domain of Sorting Nexins 7 and 30; cd06860
The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 7; cd07666
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
Paralemmin; pfam03285
Reeler, the N-terminal domain of reelin, F-spondin, and a variety of other proteins; cd08544
DOMON domain of stromal cell-derived receptor 2 (ferric chelate reductase 1) and related proteins; cd09628
DOMON domain; pfam03351
Eukaryotic cytochrome b(561), including the FRRS1 gene product; cd08760
glycogen debranching enzyme; TIGR01531
Alpha amylase catalytic domain found in glycogen debranching enzymes; cd11327
Amylo-alpha-1,6-glucosidase; pfam06202
glycogen debranching enzyme; TIGR01531
Alpha amylase catalytic domain found in glycogen debranching enzymes; cd11327
Amylo-alpha-1,6-glucosidase; pfam06202
glycogen debranching enzyme; TIGR01531
Alpha amylase catalytic domain found in glycogen debranching enzymes; cd11327
Amylo-alpha-1,6-glucosidase; pfam06202
glycogen debranching enzyme; TIGR01531
Alpha amylase catalytic domain found in glycogen debranching enzymes; cd11327
Amylo-alpha-1,6-glucosidase; pfam06202
glycogen debranching enzyme; TIGR01531
Alpha amylase catalytic domain found in glycogen debranching enzymes; cd11327
Amylo-alpha-1,6-glucosidase; pfam06202
glycogen debranching enzyme; TIGR01531
Alpha amylase catalytic domain found in glycogen debranching enzymes; cd11327
Amylo-alpha-1,6-glucosidase; pfam06202
UDP-galactose transporter; TIGR00803
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Major Facilitator Superfamily; pfam07690
chromosome segregation protein SMC, common bacterial type; TIGR02168
CCCH zinc finger in TRM13 protein; pfam11722
U11-48K-like CHHC zinc finger; pfam05253
Methyltransferase TRM13; pfam05206
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; cd06849
2-oxoisovalerate dehydrogenase E2 component
e3 binding domain; pfam02817
2-oxoacid dehydrogenases acyltransferase (catalytic domain); pfam00198
RNA 3'-phosphate cyclase; TIGR03399
RNA 3' phosphate cyclase domain (class II). These proteins function as RNA cyclase to catalyze the ATP-dependent conversion of 3'-phosphate to a 2'.3'-cyclic phosphodiester at the end of RNA molecule. A conserved catalytic histidine residue is found in...; cd00874
RNA 3'-phosphate cyclase; TIGR03399
RNA 3' phosphate cyclase domain (class II). These proteins function as RNA cyclase to catalyze the ATP-dependent conversion of 3'-phosphate to a 2'.3'-cyclic phosphodiester at the end of RNA molecule. A conserved catalytic histidine residue is found in...; cd00874
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cl00053
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cl00053
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cl00053
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Second immunoglobulin (Ig)-like domain of vascular endothelial cell adhesion molecule-1 (VCAM-1, CD106) and intercellular cell adhesion molecule-1 (ICAM-1, CD54) and similar proteins; cd07689
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Second immunoglobulin (Ig)-like domain of vascular endothelial cell adhesion molecule-1 (VCAM-1, CD106) and intercellular cell adhesion molecule-1 (ICAM-1, CD54) and similar proteins; cd07689
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Second immunoglobulin (Ig)-like domain of vascular endothelial cell adhesion molecule-1 (VCAM-1, CD106) and intercellular cell adhesion molecule-1 (ICAM-1, CD54) and similar proteins; cd07689
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cd00096
Second immunoglobulin (Ig)-like domain of vascular endothelial cell adhesion molecule-1 (VCAM-1, CD106) and intercellular cell adhesion molecule-1 (ICAM-1, CD54) and similar proteins; cd07689
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Second immunoglobulin (Ig)-like domain of vascular endothelial cell adhesion molecule-1 (VCAM-1, CD106) and intercellular cell adhesion molecule-1 (ICAM-1, CD54) and similar proteins; cd07689
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Second immunoglobulin (Ig)-like domain of vascular endothelial cell adhesion molecule-1 (VCAM-1, CD106) and intercellular cell adhesion molecule-1 (ICAM-1, CD54) and similar proteins; cd07689
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Glycosyl transferase family 64 domain; pfam09258
Glycosyl transferase family 64 domain; pfam09258
Glycosyl transferase family 64 domain; pfam09258
Glycosyl transferase family 64 domain; pfam09258
Glycosyl transferase family 64 domain; pfam09258
Cation efflux family; pfam01545
Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; COG1230
Cation efflux family; cl00316
Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; COG1230
Cation efflux family; pfam01545
Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; COG1230
Cation efflux family; cl00316
Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; COG1230
diphthine synthase; TIGR00522
Diphthine synthase, also known as DPH5; cd11647
diphthine synthase; TIGR00522
Diphthine synthase, also known as DPH5; cd11647
diphthine synthase; TIGR00522
Diphthine synthase, also known as DPH5; cd11647
7 transmembrane receptor (rhodopsin family); pfam00001
Neurogenesis glycoprotein; pfam12308
Olfactomedin-like domain; pfam02191
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Fibrillar collagen C-terminal domain; pfam01410
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Fibrillar collagen C-terminal domain; pfam01410
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Fibrillar collagen C-terminal domain; pfam01410
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Fibrillar collagen C-terminal domain; pfam01410
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Alpha amylase catalytic domain found in bacterial and eukaryotic Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); cd11317
Glycosidases [Carbohydrate transport and metabolism]; COG0366
Aamy_C domain; smart00632
Alpha amylase catalytic domain found in bacterial and eukaryotic Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); cd11317
Glycosidases [Carbohydrate transport and metabolism]; COG0366
Aamy_C domain; smart00632
Alpha amylase catalytic domain found in bacterial and eukaryotic Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); cd11317
Glycosidases [Carbohydrate transport and metabolism]; COG0366
Aamy_C domain; smart00632
Alpha amylase catalytic domain found in bacterial and eukaryotic Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); cd11317
Glycosidases [Carbohydrate transport and metabolism]; COG0366
Aamy_C domain; smart00632
Alpha amylase catalytic domain found in bacterial and eukaryotic Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); cd11317
Glycosidases [Carbohydrate transport and metabolism]; COG0366
Aamy_C domain; smart00632
Alpha amylase catalytic domain found in bacterial and eukaryotic Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); cd11317
Glycosidases [Carbohydrate transport and metabolism]; COG0366
Aamy_C domain; smart00632
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Laminin N-terminal (Domain VI); cl02806
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin N-terminal (Domain VI); cl02806
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin N-terminal (Domain VI); cl02806
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Vav pleckstrin homology (PH) domain; cd01223
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
First Src homology 3 domain of VAV3 protein; cd11981
Src homology 2 (SH2) domain found in the Vav3 proteins; cd10407
C-terminal (or second) Src homology 3 domain of VAV3 protein; cd11978
Src Homology 3 domain superfamily; cl17036
Src homology 2 (SH2) domain found in the Vav3 proteins; cd10407
C-terminal (or second) Src homology 3 domain of VAV3 protein; cd11978
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
TMPIT-like protein; pfam07851
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
TMPIT-like protein; pfam07851
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
TMPIT-like protein; pfam07851
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
N-terminal C2 in EEIG1 and EHBP1 proteins; pfam10358
Methyltransferase domain; pfam08242
Methyltransferase domain; pfam08242
PRP38 family; pfam03371
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Sec1 family; pfam00995
AT-hook-containing transcription factor; pfam12443
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
GoLoco motif; pfam02188
GoLoco motif; pfam02188
LGN motif, putative GEFs specific for G-alpha GTPases; smart00390
GoLoco motif; pfam02188
Mid-1-related chloride channel (MCLC); pfam05934
Mid-1-related chloride channel (MCLC); pfam05934
C-terminal to LisH motif; smart00668
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
C-terminal to LisH motif; smart00668
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
C-terminal to LisH motif; smart00668
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
The TATA Binding Protein (TBP) Associated Factor 13 (TAF13) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex; cd07978
Protein of unknown function (DUF1242); pfam06842
Protein of unknown function (DUF3695); pfam12494
GCC2 and GCC3; pfam07699
GCC2 and GCC3; pfam07699
GCC2 and GCC3; pfam07699
Seryl-tRNA synthetase N-terminal domain; pfam02403
seryl-tRNA synthetase
Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme bound...; cd00770
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Domain present in hormone receptors; smart00008
Domain of unknown function (DUF3497); pfam12003
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); cl12142
Immunoglobulin domain; cl11960
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
VPS10 domain; smart00602
VPS10 domain; smart00602
proteasome subunit alpha; Provisional
proteasome_alpha_type_5. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on...; cd03753
The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; cl00467
The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; cl00467
The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; cl00467
Membrane-associating domain; pfam01284
SCA7, zinc-binding domain; pfam08313
Eukaryotic cytochrome b(561), including the CYB561D2 gene product; cd08761
Eukaryotic cytochrome b(561), including the CYB561D2 gene product; cd08761
Eukaryotic cytochrome b(561), including the CYB561D2 gene product; cd08761
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine rich repeat; pfam13855
Immunoglobulin like; smart00410
7 transmembrane receptor (rhodopsin family); pfam00001
G protein alpha subunit; smart00275
Alpha subunit of G proteins (guanine nucleotide binding); cd00066
G protein alpha subunit; smart00275
Alpha subunit of G proteins (guanine nucleotide binding); cd00066
AMP deaminase; TIGR01429
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway; cd01319
AMP deaminase; TIGR01429
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway; cd01319
AMP deaminase; TIGR01429
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway; cd01319
AMP deaminase; TIGR01429
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway; cd01319
AMP deaminase; TIGR01429
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway; cd01319
Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; COG0625
GST_N family, Class Mu subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; cd03075
C-terminal, alpha helical domain of the Glutathione S-transferase family; cl02776
glutathione s-transferase; Provisional
GST_N family, Class Mu subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; cd03075
C-terminal, alpha helical domain of Class Mu Glutathione S-transferases; cd03209
Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; COG0625
GST_N family, Class Mu subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; cd03075
C-terminal, alpha helical domain of the Glutathione S-transferase family; cl02776
glutathione s-transferase; Provisional
GST_N family, Class Mu subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; cd03075
C-terminal, alpha helical domain of Class Mu Glutathione S-transferases; cd03209
glutathione s-transferase; Provisional
GST_N family, Class Mu subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; cd03075
C-terminal, alpha helical domain of Class Mu Glutathione S-transferases; cd03209
GST_N family, Class Mu subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; cd03075
C-terminal, alpha helical domain of the Glutathione S-transferase family; cl02776
glutathione s-transferase; Provisional
GST_N family, Class Mu subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; cd03075
C-terminal, alpha helical domain of the Glutathione S-transferase family; cl02776
glutathione s-transferase; Provisional
GST_N family, Class Mu subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; cd03075
C-terminal, alpha helical domain of Class Mu Glutathione S-transferases; cd03209
Pleckstrin homology-like domain; cl00273
Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins; cd11764
SAM domain of EPS8-like subfamily; cd09540
Epidermal growth factor receptor kinase substrate (EPS8) Phosphotyrosine-binding (PTB) domain; cd01210
Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins; cd11764
SAM domain of EPS8-like subfamily; cd09540
Epidermal growth factor receptor kinase substrate (EPS8) Phosphotyrosine-binding (PTB) domain; cd01210
Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins; cd11764
SAM domain of EPS8-like subfamily; cd09540
Macrophage colony stimulating factor-1 (CSF-1); pfam05337
Macrophage colony stimulating factor-1 (CSF-1); pfam05337
Macrophage colony stimulating factor-1 (CSF-1); pfam05337
Macrophage colony stimulating factor-1 (CSF-1); pfam05337
Macrophage colony stimulating factor-1 (CSF-1); pfam05337
Macrophage colony stimulating factor-1 (CSF-1); pfam05337
Macrophage colony stimulating factor-1 (CSF-1); pfam05337
Macrophage colony stimulating factor-1 (CSF-1); pfam05337
S-adenosyl-L-homocysteine hydrolase; Provisional
S-adenosyl-L-homocysteine hydrolase (AdoHycase) catalyzes the hydrolysis of S-adenosyl-L-homocysteine (AdoHyc) to form adenosine (Ado) and homocysteine (Hcy). The equilibrium lies far on the side of AdoHyc synthesis, but in nature the removal of Ado and...; cd00401
S-adenosyl-L-homocysteine hydrolase; Provisional
S-adenosyl-L-homocysteine hydrolase (AdoHycase) catalyzes the hydrolysis of S-adenosyl-L-homocysteine (AdoHyc) to form adenosine (Ado) and homocysteine (Hcy). The equilibrium lies far on the side of AdoHyc synthesis, but in nature the removal of Ado and...; cd00401
S-adenosyl-L-homocysteine hydrolase; Provisional
S-adenosyl-L-homocysteine hydrolase (AdoHycase) catalyzes the hydrolysis of S-adenosyl-L-homocysteine (AdoHyc) to form adenosine (Ado) and homocysteine (Hcy). The equilibrium lies far on the side of AdoHyc synthesis, but in nature the removal of Ado and...; cd00401
S-adenosyl-L-homocysteine hydrolase; Provisional
S-adenosyl-L-homocysteine hydrolase (AdoHycase) catalyzes the hydrolysis of S-adenosyl-L-homocysteine (AdoHyc) to form adenosine (Ado) and homocysteine (Hcy). The equilibrium lies far on the side of AdoHyc synthesis, but in nature the removal of Ado and...; cd00401
S-adenosyl-L-homocysteine hydrolase; Provisional
S-adenosyl-L-homocysteine hydrolase (AdoHycase) catalyzes the hydrolysis of S-adenosyl-L-homocysteine (AdoHyc) to form adenosine (Ado) and homocysteine (Hcy). The equilibrium lies far on the side of AdoHyc synthesis, but in nature the removal of Ado and...; cd00401
N1221-like protein; pfam07923
Domain of unknown function (DUF3402); pfam11882
N1221-like protein; pfam07923
Domain of unknown function (DUF3402); pfam11882
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Ubiquitin-like proteins; cl00155
Ubiquitin homologues; smart00213
Na(+)-dependent neurotransmitter transporter 4; solute-binding domain; cd11521
Potassium voltage-gated channel; pfam11404
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
Potassium voltage-gated channel; pfam11404
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
SPOC domain; pfam07744
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
SPOC domain; pfam07744
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Prokineticin; pfam06607
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), CD53_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model...; cd03164
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), CD53_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model...; cd03164
Frag1/DRAM/Sfk1 family; pfam10277
CDP-alcohol phosphatidyltransferase; cl00453
CDP-alcohol phosphatidyltransferase; cl00453
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
DENN (AEX-3) domain; pfam02141
dDENN domain; pfam03455
Glyco_18 domain; smart00636
This conserved domain family includes a large number of catalytically inactive chitinase-like lectins (chitolectins) including YKL-39, YKL-40 (HCGP39), YM1, oviductin, and AMCase (acidic mammalian chitinase), as well as catalytically active...; cd02872
Glyco_18 domain; smart00636
This conserved domain family includes a large number of catalytically inactive chitinase-like lectins (chitolectins) including YKL-39, YKL-40 (HCGP39), YM1, oviductin, and AMCase (acidic mammalian chitinase), as well as catalytically active...; cd02872
The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; cl10447
Glyco_18 domain; smart00636
This conserved domain family includes a large number of catalytically inactive chitinase-like lectins (chitolectins) including YKL-39, YKL-40 (HCGP39), YM1, oviductin, and AMCase (acidic mammalian chitinase), as well as catalytically active...; cd02872
Glyco_18 domain; smart00636
Chitin-binding domain type 2; smart00494
The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; cl10447
Glyco_18 domain; smart00636
Chitin-binding domain type 2; smart00494
The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; cl10447
Glyco_18 domain; smart00636
Chitin-binding domain type 2; smart00494
The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; cl10447
Glyco_18 domain; smart00636
Chitin-binding domain type 2; smart00494
The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; cl10447
Glyco_18 domain; smart00636
Chitin-binding domain type 2; smart00494
The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; cl10447
Glyco_18 domain; smart00636
Chitin-binding domain type 2; smart00494
The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; cl10447
Glyco_18 domain; smart00636
Chitin-binding domain type 2; smart00494
The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; cl10447
Glyco_18 domain; smart00636
Chitin-binding domain type 2; smart00494
Glyco_18 domain; smart00636
This conserved domain family includes a large number of catalytically inactive chitinase-like lectins (chitolectins) including YKL-39, YKL-40 (HCGP39), YM1, oviductin, and AMCase (acidic mammalian chitinase), as well as catalytically active...; cd02872
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Mitochondrial ATP synthase B chain precursor (ATP-synt_B); pfam05405
Immunoglobulin domain; cl11960
Olfactory receptor; cl10458
Immunoglobulin domain; cl11960
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Rap1 family GTPase consists of Rap1a and Rap1b isoforms; cd04175
Rap1 family GTPase consists of Rap1a and Rap1b isoforms; cd04175
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
DEAD-like helicases superfamily; smart00487
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Shal-type voltage-gated potassium channels; pfam11601
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
Domain of unknown function (DUF3399); pfam11879
Shal-type voltage-gated potassium channels; pfam11601
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
Domain of unknown function (DUF3399); pfam11879
Cortactin-binding protein-2; pfam09727
wnt family; pfam00110
found in Wnt-1; smart00097
wnt family; pfam00110
found in Wnt-1; smart00097
ST7 protein; pfam04184
Suppression of tumorigenicity 7; cd11557
Suppression of tumorigenicity 7; cd11557
ST7 protein; pfam04184
Suppression of tumorigenicity 7; cd11557
ST7 protein; pfam04184
Suppression of tumorigenicity 7; cd11557
F-actin capping protein alpha subunit; pfam01267
AAA domain; pfam13086
AAA domain; pfam13087
AAA domain; pfam13086
AAA domain; pfam13087
GTPase SAR1 and related small G proteins [General function prediction only]
Ras homology family A (RhoA)-like includes RhoA, RhoB and RhoC; cd01870
GTPase SAR1 and related small G proteins [General function prediction only]
Ras homology family A (RhoA)-like includes RhoA, RhoB and RhoC; cd01870
GTPase SAR1 and related small G proteins [General function prediction only]
Ras homology family A (RhoA)-like includes RhoA, RhoB and RhoC; cd01870
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; cd00143
TAFA family; pfam12020
TAFA family; pfam12020
monocarboxylate transporter 1; TIGR00892
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
monocarboxylate transporter 1; TIGR00892
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine rich repeat C-terminal domain; smart00082
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Subgroup of the immunoglobulin (Ig) superfamily; cd05763
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Male germ-cell putative homeodomain transcription factor; pfam12129
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Adaptin N terminal region; pfam01602
Beta2-adaptin appendage, C-terminal sub-domain; smart01020
Adaptin N terminal region; pfam01602
Beta2-adaptin appendage, C-terminal sub-domain; smart01020
Adaptin N terminal region; pfam01602
Beta2-adaptin appendage, C-terminal sub-domain; smart01020
Beta-lactamase superfamily domain; pfam12706
DNA repair metallo-beta-lactamase; pfam07522
TRF2-binding region of apollo and similar proteins; cd11662
Protein kinase domain; pfam00069
Protein Kinases, catalytic domain; cl09925
Protein kinase domain; pfam00069
Protein Kinases, catalytic domain; cl09925
Protein Kinases, catalytic domain; cl09925
Protein Kinases, catalytic domain; cl09925
Olfactomedin-like domain; pfam02191
C2A domain first repeat present in Synaptotagmins 1, 5, 6, 9, and 10; cd08385
C2 domain second repeat present in Synaptotagmins 3, 5, 6, 9, and 10; cd08403
C2A domain first repeat present in Synaptotagmins 1, 5, 6, 9, and 10; cd08385
C2 domain second repeat present in Synaptotagmins 3, 5, 6, 9, and 10; cd08403
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; smart00336
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
PHD-finger; pfam00628
Bromodomain; tif1_like subfamily. Tif1 (transcription intermediary factor 1) is a member of the tripartite motif (TRIM) protein family, which is characterized by a particular domain architecture. It functions by recruiting coactivators and/or...; cd05502
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; smart00336
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
PHD-finger; pfam00628
Bromodomain; tif1_like subfamily. Tif1 (transcription intermediary factor 1) is a member of the tripartite motif (TRIM) protein family, which is characterized by a particular domain architecture. It functions by recruiting coactivators and/or...; cd05502
Breast carcinoma amplified sequence 2 (BCAS2); pfam05700
uDENN domain; pfam03456
DENN (AEX-3) domain; pfam02141
dDENN domain; pfam03455
uDENN domain; pfam03456
DENN (AEX-3) domain; pfam02141
dDENN domain; pfam03455
AMP deaminase; TIGR01429
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway; cd01319
AMP deaminase; TIGR01429
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway; cd01319
Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B; cd04138
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
'Cold-shock' DNA-binding domain; pfam00313
SUZ-C motif; pfam12901
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
'Cold-shock' DNA-binding domain; pfam00313
SUZ-C motif; pfam12901
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
'Cold-shock' DNA-binding domain; pfam00313
SUZ-C motif; pfam12901
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
'Cold-shock' DNA-binding domain; pfam00313
SUZ-C motif; pfam12901
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
'Cold-shock' DNA-binding domain; pfam00313
SUZ-C motif; pfam12901
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
'Cold-shock' DNA-binding domain; pfam00313
SUZ-C motif; pfam12901
Protein of unknown function (DUF837); pfam05769
Protein of unknown function (DUF837); pfam05769
Synaptonemal complex protein 1 (SCP-1); pfam05483
Glycoprotein hormone beta chain homologues; cd00069
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), CD81_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment...; cd03151
Nerve growth factor family; pfam00243
Strabismus protein; pfam06638
Strabismus protein; pfam06638
Strabismus protein; pfam06638
Calsequestrin; pfam01216
PDIb family, Calsequestrin subfamily, N-terminal TRX-fold domain; Calsequestrin is the major calcium storage protein in the sarcoplasmic reticulum (SR) of skeletal and cardiac muscle. It stores calcium ions in sufficient quantities (up to 20 mM) to allow...; cd03065
PDIb family, Calsequestrin subfamily, Middle TRX-fold domain; Calsequestrin is the major calcium storage protein in the sarcoplasmic reticulum (SR) of skeletal and cardiac muscle. It stores calcium ions in sufficient quantities (up to 20 mM) to allow...; cd03066
Protein Disulfide Isomerase (PDIb') family, Calsequestrin subfamily, C-terminal TRX-fold domain; Calsequestrin is the major calcium storage protein in the sarcoplasmic reticulum (SR) of skeletal and cardiac muscle. It stores calcium ions in sufficient...; cd03074
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Mab-21 protein; pfam03281
sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit; TIGR01106
Cation transporter/ATPase, N-terminus; smart00831
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid Dehalogenase-like Hydrolases; cl11391
Cation transporting ATPase, C-terminus; pfam00689
sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit; TIGR01106
Cation transporter/ATPase, N-terminus; smart00831
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid Dehalogenase-like Hydrolases; cl11391
Cation transporting ATPase, C-terminus; pfam00689
sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit; TIGR01106
Cation transporter/ATPase, N-terminus; smart00831
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid Dehalogenase-like Hydrolases; cl11391
Cation transporting ATPase, C-terminus; pfam00689
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM) and similar proteins; cd05741
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM) and similar proteins; cd05741
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin V-Type; smart00406
Immunoglobulin; smart00409
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin V-Type; smart00406
Immunoglobulin V-set domain; pfam07686
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin V-Type; smart00406
Immunoglobulin; smart00409
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin V-Type; smart00406
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM) and similar proteins; cd05741
Immunoglobulin C2-set domain; pfam05790
Predicted coiled-coil domain-containing protein (DUF2360); pfam10152
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin V-Type; smart00406
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin V-Type; smart00406
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin V-Type; smart00406
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin V-set domain; pfam07686
Immunoglobulin V-set domain; pfam07686
Immunoglobulin V-Type; smart00406
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
GRF zinc finger; pfam06839
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cl15348
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
Filamin-type immunoglobulin domains; smart00557
Filamin/ABP280 repeat; pfam00630
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cl15348
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
Filamin/ABP280 repeat; pfam00630
Filamin-type immunoglobulin domains; smart00557
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Glycosyl hydrolase family 47; pfam01532
Domain of unknown function (DUF1693); pfam07984
Macro domain, GDAP2_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose...; cd02905
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
Macro domain, GDAP2_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose...; cd02905
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Dip2/Utp12 Family; pfam04003
T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA...; cd00182
tryptophanyl-tRNA synthetase II; Reviewed
catalytic core domain of tryptophanyl-tRNA synthetase; cd00806
catalytic core domain of tryptophanyl-tRNA synthetase; cd00806
Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; cd02809
FMN-dependent dehydrogenase; pfam01070
Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; cd02809
FMN-dependent dehydrogenase; pfam01070
human 3beta-HSD (hydroxysteroid dehydrogenase) and HSD3B1(delta 5-delta 4-isomerase)-like, extended (e) SDRs; cd09811
3-beta hydroxysteroid dehydrogenase/isomerase family; pfam01073
human 3beta-HSD (hydroxysteroid dehydrogenase) and HSD3B1(delta 5-delta 4-isomerase)-like, extended (e) SDRs; cd09811
3-beta hydroxysteroid dehydrogenase/isomerase family; pfam01073
human 3beta-HSD (hydroxysteroid dehydrogenase) and HSD3B1(delta 5-delta 4-isomerase)-like, extended (e) SDRs; cd09811
3-beta hydroxysteroid dehydrogenase/isomerase family; pfam01073
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; COG0111
D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; pfam02826
3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade; TIGR01833
'initiating' condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are characterized by the...; cd00827
3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade; TIGR01833
'initiating' condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are characterized by the...; cd00827
C-type lectin-like domain (CTLD) of the type found in Human REG-1 (lithostathine), REG-4, and avian eggshell-specific proteins: ansocalcin, structhiocalcin-1(SCA-1), and -2(SCA-2); cd03594
C-type lectin-like domain (CTLD) of the type found in Human REG-1 (lithostathine), REG-4, and avian eggshell-specific proteins: ansocalcin, structhiocalcin-1(SCA-1), and -2(SCA-2); cd03594
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family; cd04269
Disintegrin; pfam00200
ADAM Cysteine-Rich Domain; smart00608
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
LNR domain; pfam00066
LNR domain; cl02419
LNR domain; pfam00066
NOTCH protein; pfam06816
NOTCH protein; pfam07684
Ankyrin repeats (many copies); pfam13857
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13857
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Domain of unknown function (DUF3454); pfam11936
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain; smart00179
Immunoglobulin domain; cl11960
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
cyclophilin_ABH_like: Cyclophilin  A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which...; cd01926
cyclophilin_ABH_like: Cyclophilin  A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which...; cd01926
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Microtubule associated; pfam07989
TMPIT-like protein; pfam07851
Microtubule associated; pfam07989
TMPIT-like protein; pfam07851
Microtubule associated; pfam07989
TMPIT-like protein; pfam07851
Microtubule associated; pfam07989
TMPIT-like protein; pfam07851
Zinc-finger associated domain (zf-AD); pfam07776
TMPIT-like protein; pfam07851
Microtubule associated; pfam07989
Microtubule associated; pfam07989
Microtubule associated; pfam07989
Microtubule associated; pfam07989
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repulsive guidance molecule (RGM) N-terminus; pfam06535
Repulsive guidance molecule (RGM) C-terminus; pfam06534
Repulsive guidance molecule (RGM) N-terminus; pfam06535
Repulsive guidance molecule (RGM) C-terminus; pfam06534
Repulsive guidance molecule (RGM) C-terminus; pfam06534
Repulsive guidance molecule (RGM) C-terminus; pfam06534
Arrestin (or S-antigen), N-terminal domain; pfam00339
Arrestin (or S-antigen), C-terminal domain; smart01017
DNA-directed RNA polymerase III subunit Rpc31; pfam11705
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Peroxisomal biogenesis factor 11 (PEX11); pfam05648
Peroxisomal biogenesis factor 11 (PEX11); pfam05648
Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta...; cd01469
Integrin alpha (beta-propellor repeats); smart00191
Integrin alpha (beta-propellor repeats); smart00191
Integrin alpha; pfam08441
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
PINIT domain; pfam14324
MIZ/SP-RING zinc finger; pfam02891
Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; cd04694
RNA polymerase III subunit RPC82 helix-turn-helix domain; pfam08221
RNA polymerase III subunit RPC82; pfam05645
zinc-finger; pfam14369
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
ATP synthase; cl00365
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
ATP synthase; cl00365
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
ATP synthase; cl00365
Protein of unknown function (DUF3735); pfam12537
Abscisic acid G-protein coupled receptor; pfam12430
Protein of unknown function (DUF3735); pfam12537
Abscisic acid G-protein coupled receptor; pfam12430
Protein of unknown function (DUF3735); pfam12537
Abscisic acid G-protein coupled receptor; pfam12430
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain of AMP-activated protein kinase beta subunit; cd02859
5'-AMP-activated protein kinase beta subunit, interation domain; smart01010
Pyridine nucleotide-disulphide oxidoreductase; pfam13738
Flavin-binding monooxygenase-like; pfam00743
Pyridine nucleotide-disulphide oxidoreductase; pfam13738
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Macro domain, Poa1p_like family, SNF2 subfamily. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; cd03331
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Macro domain, Poa1p_like family, SNF2 subfamily. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; cd03331
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Macro domain, Poa1p_like family, SNF2 subfamily. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; cd03331
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Macro domain, Poa1p_like family, SNF2 subfamily. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; cd03331
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Macro domain, Poa1p_like family, SNF2 subfamily. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; cd03331
B-cell lymphoma 9 protein; pfam11502
Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; cl11399
Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; cd07061
Connexin; pfam00029
Gap junction channel protein cysteine-rich domain; pfam10582
Connexin; pfam00029
Gap junction channel protein cysteine-rich domain; pfam10582
Connexin; pfam00029
Gap junction channel protein cysteine-rich domain; pfam10582
Gap junction alpha-8 protein (Cx50); pfam03509
Protein of unknown function (DUF3735); pfam12537
Abscisic acid G-protein coupled receptor; pfam12430
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
cyclophilin_ABH_like: Cyclophilin  A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which...; cd01926
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
cyclophilin_ABH_like: Cyclophilin  A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which...; cd01926
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
cyclophilin_ABH_like: Cyclophilin  A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which...; cd01926
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
Repeat of unknown function (DUF1220); pfam06758
cyclophilin_ABH_like: Cyclophilin  A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which...; cd01926
cyclophilin_ABH_like: Cyclophilin  A, B and H-like cyclophilin-type peptidylprolyl cis- trans isomerase (PPIase) domain. This family represents the archetypal cystolic cyclophilin similar to human cyclophilins A, B and H. PPIase is an enzyme which...; cd01926
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Immunoglobulin domain; pfam13927
Histone H2B; smart00427
Histone H2B; smart00427
histone H3; Provisional
Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into 'beads on a string' in...; cd00076
histone H3; Provisional
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cd00074
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cd00074
histone H3; Provisional
Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into 'beads on a string' in...; cd00076
Histone H2B; smart00427
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cd00074
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cd00074
BolA-like protein; pfam01722
synaptic vesicle protein SV2; TIGR01299
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Myotubularin-related; pfam06602
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cl00053
Myotubularin-associated protein; pfam12578
Myotubularin-related; pfam06602
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cl00053
Myotubularin-associated protein; pfam12578
OTU-like cysteine protease; pfam02338
A20-like zinc fingers; smart00259
Sec1 family; pfam00995
Pleckstrin homology (PH) domain; cd00821
Antagonist of mitotic exit network protein 1; cl15308
Leucine Rich repeats (2 copies); pfam12799
Leucine Rich repeats (2 copies); pfam12799
Antagonist of mitotic exit network protein 1; cl15308
Leucine Rich repeats (2 copies); pfam12799
Carbonic anhydrase alpha, isozymes XII and XIV. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide; cd03126
Aph-1 protein; pfam06105
Aph-1 protein; pfam06105
Aph-1 protein; pfam06105
Aph-1 protein; pfam06105
ribosomal protein S21; TIGR00030
ribosomal protein S21; TIGR00030
PWI, domain in splicing factors; smart00311
pre-mRNA processing factor 3 (PRP3); pfam08572
Protein of unknown function (DUF1115); pfam06544
CID (CTD-Interacting Domain) domain family; CID is present in several RNA-processing factors such as Pcf11 and Nrd1. Pcf11 is a conserved and essential subunit of the yeast cleavage factor IA, which is required for polyadenylation-dependent 3'-RNA...; cd03562
threonyl-tRNA synthetase
TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; cd01667
Threonyl and Alanyl tRNA synthetase second additional domain; pfam07973
Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; cd00771
ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; cd00860
Extracellular matrix protein 1 (ECM1); pfam05782
Extracellular matrix protein 1 (ECM1); pfam05782
Extracellular matrix protein 1 (ECM1); pfam05782
Extracellular matrix protein 1 (ECM1); pfam05782
Extracellular matrix protein 1 (ECM1); pfam05782
Thrombospondin type 1 repeats; smart00209
ADAM-TS Spacer 1; pfam05986
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
PLAC (protease and lacunin) domain; pfam08686
Thrombospondin type 1 repeats; smart00209
ADAM-TS Spacer 1; pfam05986
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane...; cl02575
Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane...; cd06845
Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane...; cd06845
cAMP-regulated phosphoprotein/endosulfine conserved region; pfam04667
cAMP-regulated phosphoprotein/endosulfine conserved region; pfam04667
cAMP-regulated phosphoprotein/endosulfine conserved region; pfam04667
cAMP-regulated phosphoprotein/endosulfine conserved region; pfam04667
cAMP-regulated phosphoprotein/endosulfine conserved region; pfam04667
cAMP-regulated phosphoprotein/endosulfine conserved region; pfam04667
cAMP-regulated phosphoprotein/endosulfine conserved region; pfam04667
Golgi phosphoprotein 3 (GPP34); pfam05719
HORMA domain; pfam02301
HORMA domain; pfam02301
Cathepsin propeptide inhibitor domain (I29); smart00848
Peptidase C1A subfamily (MEROPS database nomenclature); composed of cysteine peptidases (CPs) similar to papain, including the mammalian CPs (cathepsins B, C, F, H, L, K, O, S, V, X and W). Papain is an endopeptidase with specific substrate preferences; cd02248
Cathepsin propeptide inhibitor domain (I29); smart00848
Peptidase C1A subfamily (MEROPS database nomenclature); composed of cysteine peptidases (CPs) similar to papain, including the mammalian CPs (cathepsins B, C, F, H, L, K, O, S, V, X and W). Papain is an endopeptidase with specific substrate preferences; cd02248
Cathepsin propeptide inhibitor domain (I29); smart00848
Peptidase C1A subfamily (MEROPS database nomenclature); composed of cysteine peptidases (CPs) similar to papain, including the mammalian CPs (cathepsins B, C, F, H, L, K, O, S, V, X and W). Papain is an endopeptidase with specific substrate preferences; cd02248
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Tudor domain; smart00333
Tudor domain; smart00333
Methyl-CpG binding domains (MBD) present in putative histone methyltransferases (HMT) such as CLLD8 and SETDB1 proteins; CLLD8 contains a MBD, a PreSET and a bifurcated SET domain, suggesting that CLLD8 might be associated with methylation-mediated...; cd01395
Pre-SET motif; pfam05033
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Tudor domain; smart00333
Tudor domain; smart00333
Methyl-CpG binding domains (MBD) present in putative histone methyltransferases (HMT) such as CLLD8 and SETDB1 proteins; CLLD8 contains a MBD, a PreSET and a bifurcated SET domain, suggesting that CLLD8 might be associated with methylation-mediated...; cd01395
Pre-SET motif; pfam05033
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Tudor domain; smart00333
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
TRAM, LAG1 and CLN8 homology domains; smart00724
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
TRAM, LAG1 and CLN8 homology domains; smart00724
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Protein of unknown function (DUF544); pfam04424
Protein of unknown function (DUF544); pfam04424
Protein of unknown function (DUF544); pfam04424
Protein of unknown function (DUF544); pfam04424
Protein of unknown function (DUF544); pfam04424
DHH family; pfam01368
Inorganic pyrophosphatase/exopolyphosphatase [Energy production and conversion]; COG1227
DHHA2 domain; pfam02833
Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2; pfam12496
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2; pfam12496
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
The Sema domain, a protein interacting module, of semaphorins and plexins; cl15693
semaphorin domain; smart00630
Plexin repeat; cl02601
The Sema domain, a protein interacting module, of semaphorin 6C (Sema6C, also called semaphorin Y); cd11268
semaphorin domain; smart00630
Plexin repeat; cl02601
The Sema domain, a protein interacting module, of semaphorins and plexins; cl15693
semaphorin domain; smart00630
Plexin repeat; cl02601
Domain of unknown function (DUF758); pfam05527
Lysine Motif is a small domain involved in binding peptidoglycan; cd00118
Tropomodulin; pfam03250
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
YL1 nuclear protein; pfam05764
YL1 nuclear protein C-terminal domain; pfam08265
YL1 nuclear protein; pfam05764
YL1 nuclear protein C-terminal domain; pfam08265
YL1 nuclear protein; pfam05764
Phosphatidylinositol phosphate kinases (PIPK) catalyze the phosphorylation of phosphatidylinositol phosphate on the fourth or fifth hydroxyl of the inositol ring, to form phosphatidylinositol bisphosphate. CD alignment  includes type II...; cd00139
Phosphatidylinositol phosphate kinases (PIPK) catalyze the phosphorylation of phosphatidylinositol phosphate on the fourth or fifth hydroxyl of the inositol ring, to form phosphatidylinositol bisphosphate. CD alignment  includes type II...; cl02572
Phosphatidylinositol phosphate kinases (PIPK) catalyze the phosphorylation of phosphatidylinositol phosphate on the fourth or fifth hydroxyl of the inositol ring, to form phosphatidylinositol bisphosphate. CD alignment  includes type II...; cd00139
Phosphatidylinositol phosphate kinases (PIPK) catalyze the phosphorylation of phosphatidylinositol phosphate on the fourth or fifth hydroxyl of the inositol ring, to form phosphatidylinositol bisphosphate. CD alignment  includes type II...; cd00139
Phosphatidylinositol phosphate kinases (PIPK) catalyze the phosphorylation of phosphatidylinositol phosphate on the fourth or fifth hydroxyl of the inositol ring, to form phosphatidylinositol bisphosphate. CD alignment  includes type II...; cl02572
Phosphatidylinositol phosphate kinases (PIPK) catalyze the phosphorylation of phosphatidylinositol phosphate on the fourth or fifth hydroxyl of the inositol ring, to form phosphatidylinositol bisphosphate. CD alignment  includes type II...; cd00139
Phosphatidylinositol phosphate kinases (PIPK) catalyze the phosphorylation of phosphatidylinositol phosphate on the fourth or fifth hydroxyl of the inositol ring, to form phosphatidylinositol bisphosphate. CD alignment  includes type II...; cl02572
26S proteasome plays a major role in eukaryotic protein breakdown, especially for ubiquitin-tagged proteins. It is an ATP-dependent protease responsible for the bulk of non-lysosomal proteolysis in eukaryotes, often using covalent modification of...; cd01452
Ubiquitin interaction motif; pfam02809
Phosphoinositide 4-kinase (PI4K), Type III, beta isoform, catalytic domain; The PI4K catalytic domain family is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein...; cd05168
Phosphoinositide 3-kinase, catalytic domain; smart00146
Phosphoinositide 4-kinase (PI4K), Type III, beta isoform, catalytic domain; The PI4K catalytic domain family is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein...; cd05168
Phosphoinositide 3-kinase, catalytic domain; smart00146
Phosphoinositide 4-kinase (PI4K), Type III, beta isoform, catalytic domain; The PI4K catalytic domain family is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein...; cd05168
Phosphoinositide 3-kinase, catalytic domain; smart00146
Phosphoinositide 4-kinase (PI4K), Type III, beta isoform, catalytic domain; The PI4K catalytic domain family is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein...; cd05168
Phosphoinositide 3-kinase, catalytic domain; smart00146
RFX DNA-binding domain; pfam02257
RFX DNA-binding domain; pfam02257
56kDa selenium binding protein (SBP56); pfam05694
56kDa selenium binding protein (SBP56); pfam05694
56kDa selenium binding protein (SBP56); pfam05694
20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]; COG0638
proteasome beta type-4 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that...; cd03760
Putative DNA-binding domain in centromere protein B, mouse jerky and transposases; smart00674
Integrase core domain; cl01316
Putative DNA-binding domain in centromere protein B, mouse jerky and transposases; smart00674
Integrase core domain; cl01316
Putative DNA-binding domain in centromere protein B, mouse jerky and transposases; smart00674
Integrase core domain; cl01316
Putative DNA-binding domain in centromere protein B, mouse jerky and transposases; smart00674
Integrase core domain; cl01316
Putative DNA-binding domain in centromere protein B, mouse jerky and transposases; smart00674
Integrase core domain; cl01316
phosphodiesterase; Provisional
chromosome segregation protein SMC, common bacterial type; TIGR02168
Myosin tail; pfam01576
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
The phosphoinositide binding Phox Homology domain of Sorting Nexin 27; cd06886
Ubiquitin domain of SNX27 (sorting nexin protein 27); cd01777
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
ELAV/HuD family splicing factor; TIGR01661
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Dimerization/Docking domain of the Regulatory subunit of cAMP-dependent protein kinase and similar domains; cl02594
Ribosomal protein L9, N-terminal domain; pfam01281
50S ribosomal protein L9; Reviewed; PRK00137
Ornithine decarboxylase antizyme; pfam02100
Ornithine decarboxylase antizyme; pfam02100
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
Tudor domain; pfam00567
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
Tudor domain; pfam00567
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
Tudor domain; pfam00567
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
Tudor domain; pfam00567
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
DNA-binding domain of Retinoid-related orphan receptors (RORs) is composed of two C4-type zinc fingers; cd06968
The ligand binding domain of Retinoid-related orphan receptors, of the nuclear receptor superfamily; cd06939
DNA-binding domain of Retinoid-related orphan receptors (RORs) is composed of two C4-type zinc fingers; cd06968
The ligand binding domain of Retinoid-related orphan receptors, of the nuclear receptor superfamily; cd06939
C2 domain; cd00030
PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; cd03443
PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; cd03443
S-100A10: A subgroup of the S-100A10 domain found in proteins similar to S100A10. S100A10 is a member of the S100 family of EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy, to which this S-100A10 group belongs, contains...; cd05024
S-100A11: S-100A11 domain found in proteins similar to S100A11. S100A11 is a member of the S-100 domain family within EF-hand Ca2+-binding proteins superfamily. Note that the S-100 hierarchy, to which this S-100A11 group belongs, contains only S-100...; cd05023
EF-hand domain pair; pfam13499
S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100...; cd00213
S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100...; cd00213
EF-hand domain pair; pfam13499
S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100...; cd00213
S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100...; cd00213
S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100...; cd00213
S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100...; cd00213
S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100...; cd00213
EF-hand domain pair; pfam13833
Involucrin of squamous epithelia N-terminus; pfam10583
autotransport protein MisL; Provisional
autotransport protein MisL; Provisional
Cornifin (SPRR) family; pfam02389
Cornifin (SPRR) family; pfam02389
autotransport protein MisL; Provisional
Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; cd06583
Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; cd06583
Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; cd06583
Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; cd06583
Calgranulins: S-100 domain found in proteins belonging to the Calgranulin subgroup of the S100 family of EF-hand calcium-modulated proteins, including S100A8, S100A9, and S100A12 . Note that the S-100 hierarchy, to which this Calgranulin group belongs; cd05030
Calgranulins: S-100 domain found in proteins belonging to the Calgranulin subgroup of the S100 family of EF-hand calcium-modulated proteins, including S100A8, S100A9, and S100A12 . Note that the S-100 hierarchy, to which this Calgranulin group belongs; cd05030
Calgranulins: S-100 domain found in proteins belonging to the Calgranulin subgroup of the S100 family of EF-hand calcium-modulated proteins, including S100A8, S100A9, and S100A12 . Note that the S-100 hierarchy, to which this Calgranulin group belongs; cd05030
S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100...; cd00213
S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100...; cd00213
S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100...; cd00213
S-100A6: S-100A6 domain found in proteins similar to S100A6. S100A6 is a member of the S100 domain family within EF-hand Ca2+-binding proteins superfamily. Note that the S-100 hierarchy, to which this S-100A6 group belongs, contains only S-100 EF-hand...; cd05029
S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100...; cd00213
S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100...; cd00213
EF-hand domain pair; pfam13499
S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100...; cd00213
EF-hand domain pair; pfam13499
S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100...; cd00213
S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100...; cd00213
S-100A13: S-100A13 domain found in proteins similar to S100A13. S100A13 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy; cd05022
EF-hand domain pair; pfam13499
S-100A13: S-100A13 domain found in proteins similar to S100A13. S100A13 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy; cd05022
S-100A13: S-100A13 domain found in proteins similar to S100A13. S100A13 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy; cd05022
S-100A13: S-100A13 domain found in proteins similar to S100A13. S100A13 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy; cd05022
S-100A13: S-100A13 domain found in proteins similar to S100A13. S100A13 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy; cd05022
S-100A13: S-100A13 domain found in proteins similar to S100A13. S100A13 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy; cd05022
S-100A13: S-100A13 domain found in proteins similar to S100A13. S100A13 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy; cd05022
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cl08302
C-terminal duplication domain of Friend of PRMT1; pfam13865
C-terminal duplication domain of Friend of PRMT1; pfam13865
domain in DSRM or ZnF_C2H2 domain containing proteins; smart00572
domain in DSRM or ZnF_C2H2 domain containing proteins; smart00572
Ligand-binding domain of type A natriuretic peptide receptor; cd06385
Receptor family ligand binding region; pfam01094
Tyrosine kinase, catalytic domain; smart00219
Catalytic domain of Protein Kinases; cd00180
Heme NO binding associated; pfam07701
Adenylyl- / guanylyl cyclase, catalytic domain; smart00044
cyclase homology domain; cd07302
Conserved protein (DUF2356); pfam10189
O-succinylbenzoate-CoA ligase; TIGR01923
AMP-binding enzyme; pfam00501
GATA zinc finger; pfam00320
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
DENN (AEX-3) domain; pfam02141
dDENN domain; pfam03455
PPR repeat family; pfam13041
Transducer of regulated CREB activity, N terminus; pfam12884
Transducer of regulated CREB activity middle domain; pfam12885
Transducer of regulated CREB activity, C terminus; pfam12886
ZIP Zinc transporter; pfam02535
Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; cl00437
basic region leucin zipper; smart00338
basic region leucin zipper; smart00338
basic region leucin zipper; smart00338
basic region leucin zipper; smart00338
basic region leucin zipper; smart00338
Jumping translocation breakpoint protein (JTB); pfam05439
GTPase SAR1 and related small G proteins [General function prediction only]
Rab GTPase families 8, 10, 13 (Rab8, Rab10, Rab13); cd01867
ribosomal protein S27; Provisional
40S ribosomal protein S27; Provisional
Archaebacterial flagellin; cl00732
Bacterial Ig-like domain 2; smart00635
Archaebacterial flagellin; cl00732
Bacterial Ig-like domain 2; smart00635
Tropomyosin; pfam00261
Tropomyosin; pfam00261
Tropomyosin; pfam00261
Tropomyosin; pfam00261
Tropomyosin; pfam00261
NICE-3 protein; pfam07406
NICE-3 protein; pfam07406
NICE-3 protein; pfam07406
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Ubiquitin-associated protein 2; pfam12478
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Ubiquitin-associated protein 2; pfam12478
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; cd00333
phospholipid-translocating P-type ATPase, flippase; TIGR01652
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid Dehalogenase-like Hydrolases; cl11391
E1-E2 ATPase; pfam00122
Immunoglobulin C-2 Type; smart00408
Interleukin-6 receptor alpha chain, binding; pfam09240
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin C-2 Type; smart00408
Interleukin-6 receptor alpha chain, binding; pfam09240
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin C-2 Type; smart00408
Interleukin-6 receptor alpha chain, binding; pfam09240
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Src homology 2 domain found in SH2 domain-containing adapter protein E (SHE); cd10391
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Tudor domain; pfam00567
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Tudor domain; pfam00567
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Cation transporter family protein; TIGR00860
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Adenosine deaminase z-alpha domain; pfam02295
Adenosine deaminase z-alpha domain; pfam02295
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase); smart00552
Adenosine deaminase z-alpha domain; pfam02295
Adenosine deaminase z-alpha domain; pfam02295
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase); smart00552
Adenosine deaminase z-alpha domain; pfam02295
Adenosine deaminase z-alpha domain; pfam02295
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase); smart00552
Adenosine deaminase z-alpha domain; pfam02295
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase); smart00552
Adenosine deaminase z-alpha domain; pfam02295
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
tRNA-specific and double-stranded RNA adenosine deaminase (RNA-specific editase); smart00552
Calcium-activated SK potassium channel; pfam03530
Ion channel; pfam07885
Calmodulin binding domain; smart01053
Calcium-activated SK potassium channel; pfam03530
Ion channel; pfam07885
Calmodulin binding domain; smart01053
Calcium-activated SK potassium channel; pfam03530
Ion channel; pfam07885
Calmodulin binding domain; smart01053
Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta subunits, the two subunits...; cl09111
Phosphomevalonate kinase; pfam04275
PEP-CTERM family integral membrane protein; TIGR02921
PHD-finger; pfam00628
SHC phosphotyrosine-binding (PTB) domain; cd01209
Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC); cd09925
SHC phosphotyrosine-binding (PTB) domain; cd01209
Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC); cd09925
SHC phosphotyrosine-binding (PTB) domain; cd01209
Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC); cd09925
SHC phosphotyrosine-binding (PTB) domain; cd01209
Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC); cd09925
SHC phosphotyrosine-binding (PTB) domain; cd01209
Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC); cd09925
Cyclin-dependent kinase regulatory subunit; pfam01111
Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA [General function prediction only]; COG1058
Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; cd00885
This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; cd01713
Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA [General function prediction only]; COG1058
Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; cd00885
This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; cd01713
Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA [General function prediction only]; COG1058
Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; cd00885
This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; cd01713
Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA [General function prediction only]; COG1058
Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; cd00885
BTB/POZ domain; pfam00651
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
BTB/POZ domain; pfam00651
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
DC-STAMP-like protein; pfam07782
DC-STAMP-like protein; pfam07782
DC-STAMP-like protein; pfam07782
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family; cd04269
Disintegrin; pfam00200
ADAM Cysteine-Rich Domain; smart00608
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family; cd04269
Disintegrin; pfam00200
ADAM Cysteine-Rich Domain; smart00608
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family; cd04269
Disintegrin; pfam00200
ADAM Cysteine-Rich Domain; smart00608
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family; cd04269
Disintegrin; pfam00200
ADAM Cysteine-Rich Domain; smart00608
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family; cd04269
Disintegrin; pfam00200
ADAM Cysteine-Rich Domain; smart00608
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family; cd04269
Disintegrin; pfam00200
ADAM Cysteine-Rich Domain; smart00608
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family; cd04269
Disintegrin; pfam00200
ADAM Cysteine-Rich Domain; smart00608
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family; cd04269
Disintegrin; pfam00200
ADAM Cysteine-Rich Domain; smart00608
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family; cd04269
Disintegrin; pfam00200
ADAM Cysteine-Rich Domain; smart00608
Receptor Binding Domain of Ephrin A; cd10425
Receptor Binding Domain of Ephrins; cl02972
Receptor Binding Domain of Ephrins; cl02972
Receptor Binding Domain of Ephrin A; cd10425
Receptor Binding Domain of Ephrin A; cd10425
Receptor Binding Domain of Ephrin A; cd10425
Sugar efflux transporter for intercellular exchange; pfam03083
Sugar efflux transporter for intercellular exchange; pfam03083
Sugar efflux transporter for intercellular exchange; pfam03083
Sugar efflux transporter for intercellular exchange; pfam03083
Sugar efflux transporter for intercellular exchange; pfam03083
Dolichol-phosphate mannosyltransferase subunit 3 (DPM3); pfam08285
Dolichol-phosphate mannosyltransferase subunit 3 (DPM3); pfam08285
Keratinocyte-associated protein 2; pfam09775
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
SPRY domain; cl02614
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cl15348
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
SPRY domain; cl02614
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
SPRY domain; cl02614
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
SPRY domain; cl02614
SEA domain; cl02507
an alternate signal peptide cleavage site has been experimentally determined, PMID: 11341784.
SEA domain; cl02507
an alternate signal peptide cleavage site has been experimentally determined, PMID: 11341784.
an alternate signal peptide cleavage site has been experimentally determined, PMID: 11341784.
SEA domain; cl02507
K+-transporting ATPase, c chain; cl00944
an alternate signal peptide cleavage site has been experimentally determined, PMID: 11341784.
Domain found in sea urchin sperm protein, enterokinase, agrin; smart00200
an alternate signal peptide cleavage site has been experimentally determined, PMID: 11341784.
Domain found in sea urchin sperm protein, enterokinase, agrin; smart00200
an alternate signal peptide cleavage site has been experimentally determined, PMID: 11341784.
Domain found in sea urchin sperm protein, enterokinase, agrin; smart00200
SEA domain; cl02507
Domain found in sea urchin sperm protein, enterokinase, agrin; smart00200
SEA domain; cl02507
SEA domain; cl02507
K+-transporting ATPase, c chain; cl00944
SEA domain; cl02507
Domain found in sea urchin sperm protein, enterokinase, agrin; smart00200
SEA domain; cl02507
Domain found in sea urchin sperm protein, enterokinase, agrin; smart00200
Domain found in sea urchin sperm protein, enterokinase, agrin; smart00200
an alternate signal peptide cleavage site has been experimentally determined, PMID: 11341784.
an alternate signal peptide cleavage site has been experimentally determined, PMID: 11341784.
Domain found in sea urchin sperm protein, enterokinase, agrin; smart00200
Domain found in sea urchin sperm protein, enterokinase, agrin; smart00200
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cl00102
Cartilage oligomeric matrix protein; pfam11598
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Thrombospondin type 3 repeat; pfam02412
Thrombospondin type 3 repeat; pfam02412
Thrombospondin type 3 repeat; pfam02412
Thrombospondin C-terminal region; pfam05735
Thrombospondin N-terminal -like domains; smart00210
Cartilage oligomeric matrix protein; pfam11598
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Thrombospondin type 3 repeat; pfam02412
Thrombospondin type 3 repeat; pfam02412
Thrombospondin type 3 repeat; pfam02412
Thrombospondin C-terminal region; pfam05735
Thrombospondin N-terminal -like domains; smart00210
Cartilage oligomeric matrix protein; pfam11598
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Thrombospondin type 3 repeat; pfam02412
Thrombospondin type 3 repeat; pfam02412
Thrombospondin type 3 repeat; pfam02412
Thrombospondin C-terminal region; pfam05735
GST_N family, Metaxin subfamily, Metaxin 1-like proteins; composed of metaxins 1 and 3, and similar proteins including Tom37 from fungi. Mammalian metaxin (or metaxin 1) and the fungal protein Tom37 are components of preprotein import complexes of the...; cd03078
C-terminal, alpha helical domain of Metaxin 1, Metaxin 3, and similar proteins; cd03212
GST_N family, Metaxin subfamily, Metaxin 1-like proteins; composed of metaxins 1 and 3, and similar proteins including Tom37 from fungi. Mammalian metaxin (or metaxin 1) and the fungal protein Tom37 are components of preprotein import complexes of the...; cd03078
C-terminal, alpha helical domain of Metaxin 1, Metaxin 3, and similar proteins; cd03212
O-Glycosyl hydrolase family 30; pfam02055
O-Glycosyl hydrolase family 30; pfam02055
O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]
O-Glycosyl hydrolase family 30; pfam02055
O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]
O-Glycosyl hydrolase family 30; pfam02055
O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]
O-Glycosyl hydrolase family 30; pfam02055
O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]
CD20-like family; pfam04103
CD20-like family; pfam04103
SCAMP family; pfam04144
SCAMP family; pfam04144
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Ion transport protein N-terminal; pfam08412
Ion transport protein; pfam00520
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; cd00288
pyruvate kinase; TIGR01064
Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; cd00288
pyruvate kinase; TIGR01064
Trans-Isoprenyl Diphosphate Synthases, head-to-tail; cd00685
Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; COG0142
Trans-Isoprenyl Diphosphate Synthases, head-to-tail; cd00685
Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; COG0142
Trans-Isoprenyl Diphosphate Synthases, head-to-tail; cd00685
Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; COG0142
Trans-Isoprenyl Diphosphate Synthases, head-to-tail; cd00685
Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; COG0142
Trans-Isoprenyl Diphosphate Synthases, head-to-tail; cd00685
RUN domain; pfam02759
Src homology 3 domain of RUN and SH3 domain-containing protein 1; cd11958
RUN domain; pfam02759
Src Homology 3 domain superfamily; cl17036
RUN domain; pfam02759
Src homology 3 domain of RUN and SH3 domain-containing protein 1; cd11958
RUN domain; pfam02759
Src homology 3 domain of RUN and SH3 domain-containing protein 1; cd11958
associated with SET domains; smart00570
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Bromodomain; ASH1_like sub-family. ASH1 (absent, small, or homeotic 1) is a member of the trithorax-group in Drosophila melanogaster, an epigenetic transcriptional regulator of HOX genes. Drosophila ASH1 has been shown to methylate specific lysines in...; cd05525
PHD-finger; pfam00628
BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional...; cd04717
Misato Segment II myosin-like domain; pfam10644
Human Misato shows similarity with Tubulin/FtsZ family of GTPases and is localized to the the outer membrane of mitochondria. It has a role in mitochondrial fusion and in mitochondrial distribution and morphology. Mutations in its Drosophila homolog; cd06060
Misato Segment II myosin-like domain; pfam10644
Human Misato shows similarity with Tubulin/FtsZ family of GTPases and is localized to the the outer membrane of mitochondria. It has a role in mitochondrial fusion and in mitochondrial distribution and morphology. Mutations in its Drosophila homolog; cd06060
Misato Segment II myosin-like domain; pfam10644
Human Misato shows similarity with Tubulin/FtsZ family of GTPases and is localized to the the outer membrane of mitochondria. It has a role in mitochondrial fusion and in mitochondrial distribution and morphology. Mutations in its Drosophila homolog; cd06060
Mitochondrial ribosomal death-associated protein 3; pfam10236
Mitochondrial ribosomal death-associated protein 3; pfam10236
Mitochondrial ribosomal death-associated protein 3; pfam10236
Mitochondrial ribosomal death-associated protein 3; pfam10236
Mitochondrial ribosomal death-associated protein 3; pfam10236
Paired amphipathic helix repeat; pfam02671
Paired amphipathic helix repeat; pfam02671
C2A domain first repeat present in Synaptotagmins 4 and 11; cd08388
C2 domain second repeat present in Synaptotagmin 4; cd08404
GTPase SAR1 and related small G proteins [General function prediction only]
Ras-like protein in all tissues (Rit), Ras-like protein in neurons (Rin) and Ras-related protein which interacts with calmodulin (Ric); cd04141
GTPase SAR1 and related small G proteins [General function prediction only]
Ras-like protein in all tissues (Rit), Ras-like protein in neurons (Rin) and Ras-related protein which interacts with calmodulin (Ric); cd04141
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
KH-II  (K homology RNA-binding domain, type II). KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins  (e.g. ribosomal protein S3), transcription factors (e.g. NusA_K), and post-transcriptional...; cl00098
7 transmembrane receptor (rhodopsin family); pfam00001
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
PH domain; pfam00169
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
PH domain; pfam00169
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
PH domain; pfam00169
Translocon-associated protein beta (TRAPB); pfam05753
Ubiquitin homologues; smart00213
Ubiquitin-like domain of hPLIC-1 and hPLIC2; cd01808
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Roadblock/LC7 domain; pfam03259
Roadblock/LC7 domain; pfam03259
Rab GTPase; Provisional
Rab GTPase family 11 (Rab11)-like includes Rab11a, Rab11b, and Rab25; cd01868
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
Intermediate filament protein; pfam00038
Lamin Tail Domain; pfam00932
Intermediate filament protein; pfam00038
Lamin Tail Domain; pfam00932
Intermediate filament protein; pfam00038
Lamin Tail Domain; pfam00932
Intermediate filament protein; pfam00038
Lamin Tail Domain; pfam00932
The Sema domain, a protein interacting module, of semaphorin 4A (Sema4A); cd11256
semaphorin domain; smart00630
Plexin repeat; pfam01437
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
The Sema domain, a protein interacting module, of semaphorin 4A (Sema4A); cd11256
semaphorin domain; smart00630
Plexin repeat; pfam01437
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
The Sema domain, a protein interacting module, of semaphorin 4A (Sema4A); cd11256
semaphorin domain; smart00630
Plexin repeat; pfam01437
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
The Sema domain, a protein interacting module, of semaphorins and plexins; cl15693
semaphorin domain; smart00630
Plexin repeat; pfam01437
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
mitochondrial carrier protein; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Nnf1; pfam03980
Nnf1; pfam03980
Nnf1; pfam03980
Nnf1; pfam03980
Nnf1; pfam03980
Nnf1; pfam03980
Nnf1; pfam03980
Domain containing Gla (gamma-carboxyglutamate) residues; smart00069
Haemolysin-III related; cl03831
Haemolysin-III related; pfam03006
Telomerase activating protein Est1; pfam10374
Est1 DNA/RNA binding domain; pfam10373
PIN domain of human telomerase-binding protein EST1, Smg5, and other similar eukaryotic homologs; cd09884
von Hippel-Landau (pVHL) tumor suppressor protein; cd05468
TCP-1 (CTT or eukaryotic type II) chaperonin family, gamma subunit. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings. In contrast to bacterial group I chaperonins; cd03337
TCP-1/cpn60 chaperonin family; pfam00118
TCP-1 (CTT or eukaryotic type II) chaperonin family, gamma subunit. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings. In contrast to bacterial group I chaperonins; cd03337
TCP-1/cpn60 chaperonin family; pfam00118
Ammonium Transporter Family; cl03012
Ammonium Transporter Family; cl03012
Ammonium Transporter Family; cl03012
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I...; cd00265
Holliday junction regulator protein family C-terminal repeat; pfam12347
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
IQ calmodulin-binding motif; cl15479
RasGAP: Ras-GTPase Activating Domain.  RasGAP functions as an enhancer of the hydrolysis of GTP that is bound to Ras-GTPases. Proteins having a RasGAP domain include p120GAP, IQGAP, Rab5-activating protein 6, and Neurofibromin.  Although the Rho (Ras...; cl02569
RasGAP C-terminus; pfam03836
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
YjeF-related protein N-terminus; cl00318
G-patch domain; pfam01585
G-patch domain; pfam01585
Immunoglobulin (Ig)-like domain of human cartilage link protein (LP); cd05877
Immunoglobulin V-Type; smart00406
Link_domain_HAPLN_module_1; this link domain is found in the first link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a HA-binding...; cd03518
Link_domain_HAPLN_module_2; this link domain is found in the second link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a...; cd03519
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Link_domain_CSPGs_modules_1_3; this extracellular link domain is found in the first and third link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan. In addition, it is found in the first link module of three other CSPGs:...; cd03517
Link_domain_CSPGs_modules_2_4; this link domain is found in the second and fourth link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan and, in the second link module of three other CSPGs: versican, neurocan, and brevican. The...; cd03520
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Link_domain_CSPGs_modules_1_3; this extracellular link domain is found in the first and third link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan. In addition, it is found in the first link module of three other CSPGs:...; cd03517
Link_domain_CSPGs_modules_2_4; this link domain is found in the second and fourth link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan and, in the second link module of three other CSPGs: versican, neurocan, and brevican. The...; cd03520
Intermediate filament protein; pfam00038
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
Lipocalin / cytosolic fatty-acid binding protein family; pfam00061
DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; COG0847
DEDDh 3'-5' exonuclease domain of Interferon Stimulated Gene product of 20 kDa, and similar proteins; cd06149
Methyltransferase domain; pfam13679
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
ribosomal protein L24, bacterial/organelle; TIGR01079
ribosomal protein L24; Validated; CHL00141
ribosomal protein L24, bacterial/organelle; TIGR01079
ribosomal protein L24; Validated; CHL00141
The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids.  The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation.  Most PWWP-domain proteins...; cl02554
The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids.  The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation.  Most PWWP-domain proteins...; cl02554
The PWWP domain is an essential part of the Hepatoma Derived Growth Factor (HDGF) family of proteins, and is necessary for DNA binding by HDGF. This family of endogenous nuclear-targeted mitogens includes HRP (HDGF-related proteins 1, 2, 3, 4, or HPR1; cd05834
Mitotic checkpoint protein PRCC_Cterm; pfam10253
Src homology 2 domain found in the SH2 domain containing protein 2A (SH2D2A); cd10416
Src homology 2 domain found in the SH2 domain containing protein 2A (SH2D2A); cd10416
Src homology 2 domain found in the SH2 domain containing protein 2A (SH2D2A); cd10416
Src homology 2 domain found in the SH2 domain containing protein 2A (SH2D2A); cd10416
Src homology 2 domain found in the SH2 domain containing protein 2A (SH2D2A); cd10416
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Fourth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC; cd04972
Immunoglobulin I-set domain; pfam07679
Fifth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC; cd04971
Catalytic domain of the Protein Tyrosine Kinase, Tropomyosin Related Kinase A; cd05092
Protein tyrosine kinase; pfam07714
Receptor L domain; pfam01030
Furin-like cysteine rich region; pfam00757
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors; cd00064
Receptor L domain; pfam01030
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Catalytic domain of Insulin Receptor-like Protein Tyrosine Kinases; cd05032
Protein tyrosine kinase; pfam07714
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Fourth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC; cd04972
Immunoglobulin I-set domain; pfam07679
Fifth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC; cd04971
Catalytic domain of the Protein Tyrosine Kinase, Tropomyosin Related Kinase A; cd05092
Protein tyrosine kinase; pfam07714
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Fourth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC; cd04972
Immunoglobulin I-set domain; pfam07679
Fifth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC; cd04971
Catalytic domain of the Protein Tyrosine Kinase, Tropomyosin Related Kinase A; cd05092
Protein tyrosine kinase; pfam07714
EMI domain; pfam07546
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein; cd08753
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein; cd08753
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Ets-domain; pfam00178
Ets-domain; pfam00178
Ets-domain; pfam00178
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Immunoglobulin domain; pfam13895
Immunoglobulin domain; pfam13895
Immunoglobulin domain; pfam13895
Immunoglobulin domain; cd00096
Immunoglobulin domain; pfam13927
Immunoglobulin domain; pfam13927
Immunoglobulin domain; pfam13895
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Immunoglobulin domain; pfam13895
Immunoglobulin domain; pfam13895
Immunoglobulin domain; pfam13895
Immunoglobulin domain; cd00096
Immunoglobulin domain; pfam13895
Immunoglobulin domain; pfam13927
Immunoglobulin domain; pfam13895
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13895
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13895
Immunoglobulin domain; cd00096
Immunoglobulin domain; pfam13895
Immunoglobulin domain; pfam13927
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13927
Immunoglobulin domain; cd00096
Immunoglobulin domain; pfam13927
Immunoglobulin domain; pfam13895
Immunoglobulin domain; cd00096
Immunoglobulin domain; pfam13927
Immunoglobulin domain; pfam13895
Immunoglobulin domain; cd00096
Immunoglobulin domain; pfam13927
Immunoglobulin domain; pfam13895
Immunoglobulin domain; cd00096
Immunoglobulin domain; pfam13927
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2); cd05759
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; pfam13895
Immunoglobulin domain; pfam13895
Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 protein (also known as Neph2); cd05898
Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain; cd07698
Class I Histocompatibility antigen, domains alpha 1 and 2; pfam00129
Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain; cd07698
Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain; cd07698
Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain; cd07698
Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain; cd07698
Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain; cd07698
Immunoglobulin domain; cl11960
Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain; cd07698
Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain; cd07698
Immunoglobulin domain; cl11960
Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain; cd07698
Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain; cd07698
Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain; cd07698
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats; smart00150
Src Homology 3 domain superfamily; cl17036
Spectrin repeat; pfam00435
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeat; pfam00435
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+ insensitive EF hand; pfam08726
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Pyrin: a protein-protein interaction domain; cd08305
HIN-200/IF120x domain; pfam02760
Pyrin: a protein-protein interaction domain; cd08305
HIN-200/IF120x domain; pfam02760
Pyrin: a protein-protein interaction domain; cd08305
HIN-200/IF120x domain; pfam02760
Pyrin: a protein-protein interaction domain; cd08305
HIN-200/IF120x domain; pfam02760
Pyrin: a protein-protein interaction domain; cd08305
HIN-200/IF120x domain; pfam02760
Pyrin: a protein-protein interaction domain; cd08305
HIN-200/IF120x domain; pfam02760
HIN-200/IF120x domain; pfam02760
Pyrin: a protein-protein interaction domain; cd08305
HIN-200/IF120x domain; pfam02760
HIN-200/IF120x domain; pfam02760
Pyrin: a protein-protein interaction domain; cd08305
conserved region found in other interferon-inducible proteins
HIN-200/IF120x domain; pfam02760
Immunoglobulin V-set domain; pfam07686
First (N-terminal) immunoglobulin (Ig)-like domain of nectin-like molcule-1 (Necl-1, also known as cell adhesion molecule3 (CADM3)); cd05882
Second immunoglobulin (Ig)-like domain of nectin-like molcule-1 (Necl-1, also known as cell adhesion molecule3 (CADM3)); cd07705
Immunoglobulin domain; pfam13895
Immunoglobulin I-set domain; pfam07679
First (N-terminal) immunoglobulin (Ig)-like domain of nectin-like molcule-1 (Necl-1, also known as cell adhesion molecule3 (CADM3)); cd05882
Immunoglobulin V-set domain; pfam07686
Second immunoglobulin (Ig)-like domain of nectin-like molcule-1 (Necl-1, also known as cell adhesion molecule3 (CADM3)); cd07705
Immunoglobulin domain; pfam13895
Immunoglobulin I-set domain; pfam07679
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Pentraxins are plasma proteins characterized by their pentameric discoid assembly and their Ca2+ dependent ligand binding, such as Serum amyloid P component (SAP) and C-reactive Protein (CRP), which are cytokine-inducible acute-phase proteins implicated...; cd00152
Pentraxins are plasma proteins characterized by their pentameric discoid assembly and their Ca2+ dependent ligand binding, such as Serum amyloid P component (SAP) and C-reactive Protein (CRP), which are cytokine-inducible acute-phase proteins implicated...; cd00152
Predicted protein-tyrosine phosphatase [Signal transduction mechanisms]; COG2453
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Immunoglobulin domain; pfam13895
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; pfam13927
Immunoglobulin domain; pfam13927
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cd00096
Tumour suppressor, Mitostatin; pfam13868
Calponin [Cytoskeleton]; COG5199
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin family repeat; pfam00402
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin C-2 Type; smart00408
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin C-2 Type; smart00408
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
N-terminal immunoglobulin (Ig)-like domain of the signaling lymphocyte activation molecule (SLAM) family, CD84_like; cd05775
N-terminal immunoglobulin (Ig)-like domain of the signaling lymphocyte activation molecule (SLAM) family, CD84_like; cd05775
Immunoglobulin domain; pfam13927
Immunoglobulin domain; cl11960
Mannosyltransferase (PIG-M); pfam05007
Inward rectifier potassium channel; pfam01007
Inward rectifier potassium channel; pfam01007
Ion transport protein; pfam00520
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit; TIGR01106
Cation transporter/ATPase, N-terminus; smart00831
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid Dehalogenase-like Hydrolases; cl11391
Cation transporting ATPase, C-terminus; pfam00689
sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit; TIGR01106
Cation transporter/ATPase, N-terminus; smart00831
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid Dehalogenase-like Hydrolases; cl11391
Cation transporting ATPase, C-terminus; pfam00689
Cation transporting ATPase, C-terminus; pfam00689
Calsequestrin; pfam01216
PDIb family, Calsequestrin subfamily, N-terminal TRX-fold domain; Calsequestrin is the major calcium storage protein in the sarcoplasmic reticulum (SR) of skeletal and cardiac muscle. It stores calcium ions in sufficient quantities (up to 20 mM) to allow...; cd03065
PDIb family, Calsequestrin subfamily, Middle TRX-fold domain; Calsequestrin is the major calcium storage protein in the sarcoplasmic reticulum (SR) of skeletal and cardiac muscle. It stores calcium ions in sufficient quantities (up to 20 mM) to allow...; cd03066
Protein Disulfide Isomerase (PDIb') family, Calsequestrin subfamily, C-terminal TRX-fold domain; Calsequestrin is the major calcium storage protein in the sarcoplasmic reticulum (SR) of skeletal and cardiac muscle. It stores calcium ions in sufficient...; cd03074
Death Effector Domain of Astrocyte phosphoprotein PEA-15; cd08338
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Pex19 protein family; pfam04614
Pex19 protein family; pfam04614
xenin precursor
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Coatomer WD associated region; pfam04053
Coatomer (COPI) alpha subunit C-terminus; pfam06957
xenin precursor
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Coatomer WD associated region; pfam04053
Coatomer (COPI) alpha subunit C-terminus; pfam06957
M28 Zn-Peptidase Nicastrin, a main component of gamma-secretase complex; cd03881
helix loop helix domain; smart00353
Strabismus protein; pfam06638
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
N-terminal immunoglobulin (Ig)-like domain of the signaling lymphocyte activation molecule (SLAM) family, CD84_like; cd05775
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
N-terminal immunoglobulin (Ig)-like domain of the signaling lymphocyte activation molecule (SLAM) family, CD84_like; cd05775
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13927
N-terminal immunoglobulin (Ig)-like domain of the signaling lymphocyte activation molecule (SLAM) family, CD84_like; cd05775
Immunoglobulin domain; pfam13927
N-terminal immunoglobulin (Ig)-like domain of the signaling lymphocyte activation molecule (SLAM) family, CD84_like; cd05775
Immunoglobulin domain; pfam13927
N-terminal immunoglobulin (Ig)-like domain of the signaling lymphocyte activation molecule (SLAM) family, CD84_like; cd05775
Immunoglobulin domain; pfam13927
Signaling lymphocytic activation molecule (SLAM) protein; pfam06214
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM) and similar proteins; cd05741
Immunoglobulin domain; pfam13927
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM) and similar proteins; cd05741
Immunoglobulin domain; pfam13927
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13927
Immunoglobulin V-set domain; pfam07686
N-terminal immunoglobulin (Ig)-like domain of the signaling lymphocyte activation molecule (SLAM) family, CD84_like; cd05775
Immunoglobulin domain; pfam13927
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13927
Immunoglobulin V-set domain; pfam07686
N-terminal immunoglobulin (Ig)-like domain of the signaling lymphocyte activation molecule (SLAM) family, CD84_like; cd05775
Immunoglobulin domain; pfam13927
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13927
Immunoglobulin V-set domain; pfam07686
N-terminal immunoglobulin (Ig)-like domain of the signaling lymphocyte activation molecule (SLAM) family, CD84_like; cd05775
Immunoglobulin domain; pfam13927
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
N-terminal immunoglobulin (Ig)-like domain of the signaling lymphocyte activation molecule (SLAM) family, CD84_like; cd05775
Natural killer cell receptor 2B4; pfam11465
Natural killer cell receptor 2B4; pfam11465
Immunoglobulin domain; cl11960
Natural killer cell receptor 2B4; pfam11465
Immunoglobulin domain; cl11960
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cl00085
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cl00085
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; cl00125
Member of the Rhodanese Homology Domain superfamily. This CD includes the heat shock protein 67B2 of Drosophila melanogaster and other similar proteins, many of which are uncharacterized; cd01519
Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; cl00125
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
RhoGAP_CdGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP...; cd04384
GTPase-activator protein for Rho-like GTPases; smart00324
RhoGAP_CdGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP...; cd04384
GTPase-activator protein for Rho-like GTPases; smart00324
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Second immunoglobulin (Ig) domain of nectin-3 (also known as poliovirus receptor related protein 3), nectin-4 (poliovirus receptor related protein 4) and similar proteins; cd07704
Immunoglobulin domain; cd00096
Galactose oxidase, central domain; cl02701
Galactose oxidase, central domain; cl02701
Galactose oxidase, central domain; cl02701
Prefoldin subunit; pfam01920
Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; cl11424
Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases); cd07572
nitrilase
Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases); cd07572
nitrilase
Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases); cd07572
nitrilase
Death Effector Domain of DEDD; cd08790
Death Effector Domain of DEDD; cd08790
Death Effector Domain of DEDD; cd08790
Ubiquitin-fold modifier-conjugating enzyme 1; pfam08694
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02674
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02674
Protoporphyrinogen oxidase [Coenzyme metabolism]; COG1232
NAD(P)-binding Rossmann-like domain; pfam13450
Protoporphyrinogen oxidase [Coenzyme metabolism]; COG1232
NAD(P)-binding Rossmann-like domain; pfam13450
Beta-4-Galactosyltransferase is involved in the formation of the poly-N-acetyllactosamine core structures present in glycoproteins and glycosphingolipids; cd00899
Beta-4-Galactosyltransferase is involved in the formation of the poly-N-acetyllactosamine core structures present in glycoproteins and glycosphingolipids; cd00899
Beta-4-Galactosyltransferase is involved in the formation of the poly-N-acetyllactosamine core structures present in glycoproteins and glycosphingolipids; cd00899
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that...; cd04273
ADAM cysteine-rich; cl15456
Thrombospondin type 1 repeats; smart00209
ADAM-TS Spacer 1; pfam05986
NADH dehydrogenase subunit D; Validated
Respiratory-chain NADH dehydrogenase, 49 Kd subunit; pfam00346
NADH dehydrogenase subunit D; Validated
Respiratory-chain NADH dehydrogenase, 49 Kd subunit; pfam00346
T-cell surface glycoprotein CD3 zeta chain; pfam11628
Immunoreceptor tyrosine-based activation motif; pfam02189
Apolipoprotein A-II (ApoA-II); pfam04711
Translocase of outer mitochondrial membrane 40 (Tom40); cd07305
DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers; cl02596
The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators; cl11397
DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers; cl02596
The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators; cl11397
DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers; cl02596
The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators; cl11397
DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers; cl02596
The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators; cl11397
The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers; cd07156
The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators; cl11397
The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers; cd07156
The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators; cl11397
The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers; cd07156
The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators; cl11397
DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers; cl02596
The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators; cl11397
DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers; cl02596
The ligand binding domain of xenobiotic receptors:pregnane X receptor and constitutive androstane receptor; cd06934
DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers; cl02596
The ligand binding domain of xenobiotic receptors:pregnane X receptor and constitutive androstane receptor; cd06934
The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers; cd07156
The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators; cl11397
The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers; cd07156
The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators; cl11397
The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers; cd07156
The ligand binding domain of xenobiotic receptors:pregnane X receptor and constitutive androstane receptor; cd06934
The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers; cd07156
The ligand binding domain of xenobiotic receptors:pregnane X receptor and constitutive androstane receptor; cd06934
The DNA-binding domain of vitamin D receptors (VDR) like nuclear receptor family is composed of two C4-type zinc fingers; cd07156
The ligand binding domain of xenobiotic receptors:pregnane X receptor and constitutive androstane receptor; cd06934
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain of Protein zero (P0); cd05879
Myelin-PO cytoplasmic C-term p65 binding region; pfam10570
Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; cd03499
Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; cd03499
Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; cd03499
Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; cd03499
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
heat shock 70 kDa protein; Provisional
Nucleotide-binding domain of HSPA1-A, -B, -L, HSPA-2, -6, -7, -8, and similar proteins; cd10233
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13927
Immunoglobulin domain; pfam13927
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13927
Immunoglobulin domain; pfam13927
Immunoglobulin domain; pfam13927
Frst immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05752
Second immunoglobulin (Ig)-like domain of Fcgamma-receptors (FcgammaRs) and similar proteins; cd05753
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
basic region leucin zipper; smart00338
Olfactomedin-like domain; pfam02191
DYC-1 (DYB-1 binding and Capon related) Phosphotyrosine-binding (PTB) domain; cd01270
DYC-1 (DYB-1 binding and Capon related) Phosphotyrosine-binding (PTB) domain; cd01270
Src homology 2 (SH2) domain found in SLAM-associated protein (SAP)1; cd10342
Catalytic domain of Protein Kinases; cd00180
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Protein kinase domain; pfam00069
Catalytic domain of Protein Kinases; cd00180
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Protein kinase domain; pfam00069
Catalytic domain of Protein Kinases; cd00180
UDP-N-acetylglucosamine pyrophosphorylase; Provisional
UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc; cd04193
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 2; cd05095
Protein kinase; unclassified specificity; smart00221
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Catalytic domain of the Protein Tyrosine Kinase, Discoidin Domain Receptor 2; cd05095
Protein kinase; unclassified specificity; smart00221
Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; COG1028
3-keto steroid reductase, classical (c) SDRs; cd08941
Regulator of G protein signaling (RGS) domain found in the RGS4 protein; cd08714
Regulator of G protein signaling (RGS) domain found in the RGS4 protein; cd08714
Regulator of G protein signaling (RGS) domain superfamily; cl02565
Regulator of G protein signaling (RGS) domain found in the RGS5 protein; cd08717
Regulator of G protein signaling (RGS) domain superfamily; cl02565
Regulator of G protein signaling (RGS) domain superfamily; cl02565
Regulator of G protein signaling (RGS) domain superfamily; cl02565
Nuf2 family; pfam03800
Nuf2 family; pfam03800
PBC domain; pfam03792
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
PBC domain; pfam03792
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
PBC domain; pfam03792
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
The first LIM domain of Lmx1a; cd09370
The second LIM domain of Lmx1a and Lmx1b; cd09378
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
The first LIM domain of Lmx1a; cd09370
The second LIM domain of Lmx1a and Lmx1b; cd09378
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Nuclear/hormone receptor activator site AF-1; pfam11825
DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers; cd06956
The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily; cd06943
DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers; cd06956
The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily; cd06943
DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers; cd06956
The ligand binding domain of the retinoid X receptor and Ultraspiracle, members of nuclear receptor superfamily; cd06943
Leucine rich repeat N-terminal domain; smart00013
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine Rich repeats (2 copies); pfam12799
MAPEG family; pfam01124
betaine aldehyde dehydrogenase; Provisional
NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1; cd07090
Integral membrane protein DUF106; pfam01956
Integral membrane protein DUF106; pfam01956
Integral membrane protein DUF106; pfam01956
Uridine kinase [Nucleotide transport and metabolism]; COG0572
Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; cd02023
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Brinker DNA-binding domain; pfam09607
Putative DNA-binding domain in centromere protein B, mouse jerky and transposases; smart00674
DDE superfamily endonuclease; pfam03184
Transcriptional regulator of RNA polII, SAGA, subunit; pfam12767
High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I...; cd00084
piRNA pathway germ-plasm component; pfam13017
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin C-2 Type; smart00408
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
Pou domain - N-terminal to homeobox domain; cl02582
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Pou domain - N-terminal to homeobox domain; cl02582
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Pou domain - N-terminal to homeobox domain; cl02582
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
T-cell surface glycoprotein CD3 zeta chain; pfam11628
Immunoreceptor tyrosine-based activation motif; pfam02189
Immunoreceptor tyrosine-based activation motif; pfam02189
T-cell surface glycoprotein CD3 zeta chain; pfam11628
Immunoreceptor tyrosine-based activation motif; pfam02189
Immunoreceptor tyrosine-based activation motif; pfam02189
Pyridoxamine 5'-phosphate oxidase; pfam13883
RCSD region; pfam05177
Immunoglobulin (Ig)-like domain of Protein zero (P0) and similar proteins; cd05715
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
cyclase homology domain; cd07302
Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; COG2114
cyclase homology domain; cd07302
cyclase homology domain; cd07302
Uncharacterized protein family (UPF0041); pfam03650
Uncharacterized protein family (UPF0041); pfam03650
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
TIP41-like family; pfam04176
TIP41-like family; pfam04176
Got1/Sft2-like family; pfam04178
T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA...; cd00182
Chemokine_C, C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273)...; cd00271
Chemokine_C, C or lymphotactin subgroup, 1 of 4 subgroup designations of chemokines based on the arrangement of two N-terminal, conserved cysteine residues. Most of the known chemokines (cd00169) belong to either the CC (cd00272) or CXC (cd00273)...; cd00271
Sodium Potassium ATPase beta subunit; TIGR01107
Domains in hypothetical proteins in Drosophila, C. elegans and mammals. Occurs singly in some nucleoside diphosphate kinases; smart00676
Nucleoside diphosphate kinase 7 domain A (NDPk7A): The nm23-H7 class of nucleoside diphosphate kinase (NDPk7) consists of an N-terminal DM10 domain and two functional catalytic NDPk modules, NDPk7A and NDPk7B. The function of the DM10 domain, which also...; cd04415
Nucleoside diphosphate kinase 7 domain B (NDPk7B): The nm23-H7 class of nucleoside diphosphate kinase (NDPk7) consists of an N-terminal DM10 domain and two functional catalytic NDPk modules, NDPk7A and NDPk7B. The function of the DM10 domain, which also...; cd04412
Repeat of unknown function (DUF1126); cl02728
Nucleoside diphosphate kinase 7 domain A (NDPk7A): The nm23-H7 class of nucleoside diphosphate kinase (NDPk7) consists of an N-terminal DM10 domain and two functional catalytic NDPk modules, NDPk7A and NDPk7B. The function of the DM10 domain, which also...; cd04415
Nucleoside diphosphate kinase 7 domain B (NDPk7B): The nm23-H7 class of nucleoside diphosphate kinase (NDPk7) consists of an N-terminal DM10 domain and two functional catalytic NDPk modules, NDPk7A and NDPk7B. The function of the DM10 domain, which also...; cd04412
DASH complex subunit Hsk3 like; pfam08227
Reduced folate carrier; pfam01770
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]; COG2132
Cytochrome C oxidase subunit II, periplasmic domain; cl11412
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
C-type lectin-like domain (CTLD) of the type found in the type 1 transmembrane proteins:  P(platlet)-, E(endothelial)-, and L(leukocyte)- selectins (sels); cd03592
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
C-type lectin-like domain (CTLD) of the type found in the type 1 transmembrane proteins:  P(platlet)-, E(endothelial)-, and L(leukocyte)- selectins (sels); cd03592
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
C-type lectin-like domain (CTLD) of the type found in the type 1 transmembrane proteins:  P(platlet)-, E(endothelial)-, and L(leukocyte)- selectins (sels); cd03592
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
Protein kinase domain; pfam00069
Protein Kinases, catalytic domain; cl09925
Protein kinase domain; pfam00069
Protein Kinases, catalytic domain; cl09925
Kinesin-associated protein (KAP); pfam05804
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Kinesin-associated protein (KAP); pfam05804
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Kinesin-associated protein (KAP); pfam05804
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Kinesin-associated protein (KAP); pfam05804
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Transcriptional activator; pfam04949
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
OAR domain; pfam03826
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Flavin-binding monooxygenase-like; pfam00743
NAD(P)-binding Rossmann-like domain; pfam13450
Flavin-binding monooxygenase-like; pfam00743
NAD(P)-binding Rossmann-like domain; pfam13450
Pyridine nucleotide-disulphide oxidoreductase; pfam13738
NAD(P)-binding Rossmann-like domain; pfam13450
Flavin-binding monooxygenase-like; pfam00743
NAD(P)-binding Rossmann-like domain; pfam13450
Flavin-binding monooxygenase-like; pfam00743
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
BAT2 N-terminus; pfam07001
Centrosome microtubule-binding domain of Cep57; pfam06657
Olfactomedin-like domain; cl02549
Synaptobrevin; pfam00957
Synaptobrevin; pfam00957
Methyltransferase domain; pfam13847
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
Methyltransferase domain; pfam13847
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
Methyltransferase domain; pfam08241
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
Dynamin_like protein family includes dynamins and Mx proteins; cd08771
Dynamin family; pfam00350
Dynamin central region; pfam01031
Dynamin pleckstrin homology (PH) domain; cd01256
Dynamin GTPase effector domain; pfam02212
Dynamin_like protein family includes dynamins and Mx proteins; cd08771
Dynamin family; pfam00350
Dynamin central region; pfam01031
Dynamin pleckstrin homology (PH) domain; cd01256
Dynamin GTPase effector domain; pfam02212
Phosphatidylinositol N-acetylglucosaminyltransferase; pfam06432
Phosphatidylinositol N-acetylglucosaminyltransferase; pfam06432
Sad1 / UNC-like C-terminal; pfam07738
Sad1 / UNC-like C-terminal; pfam07738
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cd00184
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cl00147
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cd00184
Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; COG0450
Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by...; cd03016
NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; COG0025
Ion transport protein; pfam00520
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
kelch-like protein; Provisional
BTB/POZ domain; pfam00651
BTB And C-terminal Kelch; pfam07707
Kelch domain; smart00612
Kelch domain; smart00612
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch motif; pfam01344
Kinetochore complex Sim4 subunit Fta1; pfam13092
Kinetochore complex Sim4 subunit Fta1; pfam13092
Kinetochore complex Sim4 subunit Fta1; pfam13092
aspartyl-tRNA synthetase; Validated; PRK00476
EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; cd04317
Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of the...; cd00777
GAD domain; pfam02938
Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it attaches...; cl00268
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
BTB/POZ domain; pfam00651
Antithrombin is a serine proteinase inhibitor (serpin) which controls the process of coagulation. It is the most important anticoagulant molecule in mammalian circulation systems, controlled by its interaction with the co-factor, heparin, which...; cd02045
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger C-x8-C-x5-C-x3-H type (and similar); pfam00642
GAPCenA Phosphotyrosine-binding (PTB) domain; cd01211
Kinesin protein; pfam12473
GTPase-activating protein [General function prediction only]
Rab-GTPase-TBC domain; pfam00566
7 transmembrane receptor (rhodopsin family); pfam00001
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
Tektin family; pfam03148
Siah interacting protein, N terminal; pfam09032
p23_like domain found in proteins similar to Calcyclin-Binding Protein(CacyBP)/Siah-1-interacting protein (SIP). CacyBP/SIP interacts with S100A6 (calcyclin), with some other members of the S100 family, with tubulin, and with Siah-1 and Skp-1. The latter...; cd06468
SGS domain; pfam05002
p23_like domain found in proteins similar to Calcyclin-Binding Protein(CacyBP)/Siah-1-interacting protein (SIP). CacyBP/SIP interacts with S100A6 (calcyclin), with some other members of the S100 family, with tubulin, and with Siah-1 and Skp-1. The latter...; cd06468
SGS domain; pfam05002
Ribosomal protein S14p/S29e; cl00355
EGF-like domain; pfam07974
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
EGF-like domain; pfam07974
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
EGF-like domain; pfam07974
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Concanavalin A-like lectin/glucanases superfamily; pfam13385
LNR domain; pfam00066
Zinc-dependent metalloprotease, pappalysin_like subfamily. The pregnancy-associated plasma protein A (PAPP-A or pappalysin-1) cleaves insulin-like growth factor-binding proteins 4 and 5, thereby promoting cell growth by releasing bound growth factor; cd04275
Myxococcus cysteine-rich repeat; TIGR02232
Domain of unknown function (DUF4215); pfam13948
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
LNR domain; pfam00066
Concanavalin A-like lectin/glucanases superfamily; pfam13385
LNR domain; pfam00066
LNR domain; cl02419
Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; cl00064
membrane-attack complex / perforin; smart00457
membrane-attack complex / perforin; smart00457
membrane-attack complex / perforin; smart00457
Vesicle coat trafficking protein Sec16 mid-region; pfam12932
Ancestral coatomer element 1 (ACE1) of COPII coat complex assembly protein Sec16; cd09233
RAS GTPase-activating protein (GAP) CG5898 Pleckstrin homology (PH) domain; cd01245
C2 domain present in Ras GTPase activating protein (GAP) family; cd04013
The DAB2IP family of Ras GTPase-activating proteins includes DAB2IP, nGAP, and Syn GAP. Disabled 2 interactive protein, (DAB2IP; also known as ASK-interacting protein 1 (AIP1)), is a member of the GTPase-activating proteins, down-regulates Ras-mediated...; cd05136
Domain of unknown function (DUF3498); pfam12004
RAS GTPase-activating protein (GAP) CG5898 Pleckstrin homology (PH) domain; cd01245
C2 domain present in Ras GTPase activating protein (GAP) family; cd04013
The DAB2IP family of Ras GTPase-activating proteins includes DAB2IP, nGAP, and Syn GAP. Disabled 2 interactive protein, (DAB2IP; also known as ASK-interacting protein 1 (AIP1)), is a member of the GTPase-activating proteins, down-regulates Ras-mediated...; cd05136
Domain of unknown function (DUF3498); pfam12004
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
Pleckstrin homology (PH) domain; cd00821
The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1...; cl02720
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
C-terminal putative kinase domain of FAM20B xylose kinase; cd10470
Torsin; pfam06309
ATPases associated with a variety of cellular activities; smart00382
Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase; cd11850
Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins; cd09935
Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase; cd05052
Protein tyrosine kinase; pfam07714
F-actin binding; pfam08919
Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase; cd11850
Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins; cd09935
Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase; cd05052
Protein tyrosine kinase; pfam07714
F-actin binding; pfam08919
Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase; cd11850
Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins; cd09935
Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase; cd05052
Protein tyrosine kinase; pfam07714
F-actin binding; pfam08919
Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase; cd11850
Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins; cd09935
Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase; cd05052
Protein tyrosine kinase; pfam07714
F-actin binding; pfam08919
Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase; cd11850
Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins; cd09935
Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase; cd05052
Protein tyrosine kinase; pfam07714
F-actin binding; pfam08919
Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase; cd11850
Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins; cd09935
Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase; cd05052
Protein tyrosine kinase; pfam07714
F-actin binding; pfam08919
Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase; cd11850
Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins; cd09935
Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase; cd05052
Protein tyrosine kinase; pfam07714
F-actin binding; pfam08919
Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase; cd11850
Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins; cd09935
Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase; cd05052
Protein tyrosine kinase; pfam07714
MBOAT, membrane-bound O-acyltransferase family; cl00738
MBOAT, membrane-bound O-acyltransferase family; cl00738
MBOAT, membrane-bound O-acyltransferase family; cl00738
Axonemal dynein light chain; pfam10211
Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; COG0330
Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; cd03403
The first LOTUS domain on Tudor-containing protein 5 (TDRD5); cd09985
The second LOTUS domain on Tudor-containing protein 5 (TDRD5); cd09975
The third LOTUS domain on Tudor-containing protein 5 (TDRD5); cd09976
Tudor domain; pfam00567
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
The first LOTUS domain on Tudor-containing protein 5 (TDRD5); cd09985
The second LOTUS domain on Tudor-containing protein 5 (TDRD5); cd09975
The third LOTUS domain on Tudor-containing protein 5 (TDRD5); cd09976
Tudor domain; pfam00567
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
The first LOTUS domain on Tudor-containing protein 5 (TDRD5); cd09985
The second LOTUS domain on Tudor-containing protein 5 (TDRD5); cd09975
The third LOTUS domain on Tudor-containing protein 5 (TDRD5); cd09976
Tudor domain; pfam00567
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
The first LOTUS domain on Tudor-containing protein 5 (TDRD5); cd09985
The second LOTUS domain on Tudor-containing protein 5 (TDRD5); cd09975
The third LOTUS domain on Tudor-containing protein 5 (TDRD5); cd09976
Tudor domain; pfam00567
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
Tudor domain; pfam00567
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
Lamina-associated polypeptide 1C (LAP1C); pfam05609
Lamina-associated polypeptide 1C (LAP1C); pfam05609
Lamina-associated polypeptide 1C (LAP1C); pfam05609
Lamina-associated polypeptide 1C (LAP1C); pfam05609
CAP-Gly domain; pfam01302
PDIa family, Quiescin-sulfhydryl oxidase (QSOX) subfamily; QSOX is a eukaryotic protein containing an N-terminal redox active TRX domain, similar to that of PDI, and a small C-terminal flavin adenine dinucleotide (FAD)-binding domain homologous to the...; cd02992
Erv1 / Alr family; pfam04777
PDIa family, Quiescin-sulfhydryl oxidase (QSOX) subfamily; QSOX is a eukaryotic protein containing an N-terminal redox active TRX domain, similar to that of PDI, and a small C-terminal flavin adenine dinucleotide (FAD)-binding domain homologous to the...; cd02992
Erv1 / Alr family; pfam04777
The first LIM domain of Lhx4; cd09468
The second LIM domain of Lhx3-Lhx4 family; cd09376
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Acyl CoA binding protein; pfam00887
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
SPX domain; pfam03105
EXS family; pfam03124
SPX domain; pfam03105
EXS family; pfam03124
Syntaxin 6, N-terminal; pfam09177
Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in...; cd00193
Class I Histocompatibility antigen, domains alpha 1 and 2; pfam00129
Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain; cd07698
Class I Histocompatibility antigen, domains alpha 1 and 2; pfam00129
Class I Histocompatibility antigen, domains alpha 1 and 2; pfam00129
Class I Histocompatibility antigen, domains alpha 1 and 2; pfam00129
Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain; cd07698
Immediate early response protein (IER); pfam05760
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Voltage gated calcium channel IQ domain; pfam08763
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
glutamine synthetase
Glutamine synthetase, beta-Grasp domain; pfam03951
Glutamine synthetase, catalytic domain; pfam00120
glutamine synthetase
Glutamine synthetase, beta-Grasp domain; pfam03951
Glutamine synthetase, catalytic domain; pfam00120
glutamine synthetase
Glutamine synthetase, beta-Grasp domain; pfam03951
Glutamine synthetase, catalytic domain; pfam00120
Family of unknown function (DUF716); pfam04819
Uncharacterized Regulator of G protein Signaling (RGS) domain subfamily, child 2; cd08728
Regulator of G protein signaling (RGS) domain superfamily; cl02565
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Protein kinase domain; pfam00069
Protein Kinases, catalytic domain; cl09925
Protein Kinases, catalytic domain; cl09925
RNase domain (also known as the kinase extension nuclease domain) of RNase L; cd10423
Regulator of G protein signaling (RGS) domain found in the RGS16 protein; cd08710
Regulator of G protein signaling (RGS) domain found in the RGS8 protein; cd08711
Regulator of G protein signaling (RGS) domain found in the RGS8 protein; cd08711
Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; COG0329
TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; cl09108
Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; COG0329
TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; cl09108
Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; COG0329
N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); cd00954
Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; COG0329
TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; cl09108
TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; cl09108
Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; COG0329
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
HrpA-like helicases [DNA replication, recombination, and repair]; COG1643
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Helicase associated domain (HA2); pfam04408
Oligonucleotide/oligosaccharide-binding (OB)-fold; pfam07717
Right handed beta helix region; pfam13229
N-terminal domain
Laminin N-terminal (Domain VI); pfam00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
contains 4.5 EGF-like repeats
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin B (Domain IV); pfam00052
contains 6.5 EGF-like repeats
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
C-terminal domain
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); smart00283
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin B domain; smart00281
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; COG0840
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin B domain; smart00281
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; COG0840
Nicotinamide/nicotinate mononucleotide adenylyltransferase, Eukaryotic; cd09286
nucleotidyl transferase superfamily; cl00015
Telomerase activating protein Est1; pfam10374
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Est1 DNA/RNA binding domain; pfam10373
Telomerase activating protein Est1; pfam10374
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Est1 DNA/RNA binding domain; pfam10373
Telomerase activating protein Est1; pfam10374
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Est1 DNA/RNA binding domain; pfam10373
Telomerase activating protein Est1; pfam10374
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Est1 DNA/RNA binding domain; pfam10373
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
N-terminal (or first) Src Homology 3 domain of the p67phox subunit of NADPH oxidase; cd11871
A PB1 domain is present in p67 proteins which forms a signaling complex with p40, a crucial step for activation of  NADPH oxidase during phagocytosis. PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in...; cd06406
C-terminal (or second) Src Homology 3 domain of the p67phox subunit of NADPH oxidase; cd12046
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
N-terminal (or first) Src Homology 3 domain of the p67phox subunit of NADPH oxidase; cd11871
A PB1 domain is present in p67 proteins which forms a signaling complex with p40, a crucial step for activation of  NADPH oxidase during phagocytosis. PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in...; cd06406
C-terminal (or second) Src Homology 3 domain of the p67phox subunit of NADPH oxidase; cd12046
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
N-terminal (or first) Src Homology 3 domain of the p67phox subunit of NADPH oxidase; cd11871
A PB1 domain is present in p67 proteins which forms a signaling complex with p40, a crucial step for activation of  NADPH oxidase during phagocytosis. PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in...; cd06406
C-terminal (or second) Src Homology 3 domain of the p67phox subunit of NADPH oxidase; cd12046
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
N-terminal (or first) Src Homology 3 domain of the p67phox subunit of NADPH oxidase; cd11871
A PB1 domain is present in p67 proteins which forms a signaling complex with p40, a crucial step for activation of  NADPH oxidase during phagocytosis. PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in...; cd06406
C-terminal (or second) Src Homology 3 domain of the p67phox subunit of NADPH oxidase; cd12046
ARP2/3 complex 16 kDa subunit (p16-Arc); pfam04699
ARP2/3 complex 16 kDa subunit (p16-Arc); pfam04699
APOBEC-like N-terminal domain; pfam08210
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
Ubiquitin domain of  RalGDS-like factor (RLF) and related proteins; cd00153
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; cd00761
Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; cd06532
TRNA-intron endonuclease catalytic domain; pfam12858
TRNA-intron endonuclease catalytic domain; pfam12858
Glycosyl hydrolase family 47; pfam01532
PA_EDEM3_like: protease associated domain (PA) domain-containing EDEM3-like proteins. This group contains various PA domain-containing proteins similar to mouse EDEM3 (ER-degradation-enhancing mannosidase-like 3 protein). EDEM3 contains a region, similar...; cd02126
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
N(2),N(2)-dimethylguanosine tRNA methyltransferase; Provisional
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
N(2),N(2)-dimethylguanosine tRNA methyltransferase; Provisional
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
PIN domain; cd09880
PIN domain; cd09880
BTB/POZ domain; pfam00651
BTB And C-terminal Kelch; smart00875
Kelch domain; smart00612
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch domain; smart00612
Kelch motif; pfam01344
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cd00198
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin domain; cd00096
Immunoglobulin C-2 Type; smart00408
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Nidogen, G2 domain; Nidogen is an important component of the basement membrane, an extracellular sheet-like matrix. Nidogen is a multifunctional protein that interacts with many other basement membrane proteins, like collagen, perlecan, lamin, and has a...; cd00255
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Somatomedin B -like domains; smart00201
Somatomedin B -like domains; smart00201
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
Somatomedin B -like domains; smart00201
Somatomedin B -like domains; smart00201
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
Somatomedin B -like domains; smart00201
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
Somatomedin B -like domains; smart00201
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
TPR/MLP1/MLP2-like protein; pfam07926
START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; cl14643
START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; cl14643
START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; cl14643
Phosducin (Phd)-like family, Phd subfamily; Phd is a cytosolic regulator of G protein functions. It specifically binds G protein betagamma (Gbg)-subunits with high affinity, resulting in the solubilization of Gbg from the plasma membrane. This impedes...; cd02987
Phosducin (Phd)-like family, Phd subfamily; Phd is a cytosolic regulator of G protein functions. It specifically binds G protein betagamma (Gbg)-subunits with high affinity, resulting in the solubilization of Gbg from the plasma membrane. This impedes...; cd02987
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Animal prostaglandin endoperoxide synthase and related bacterial proteins; cd09816
C2 domain present in cytosolic PhosphoLipase A2 (cPLA2); cd04036
Cytoplasmic phospholipase A2, catalytic subunit; smart00022
Group IVA cytosolic phospholipase A2; catalytic domain; Ca-dependent; cd07200
Group IVA cytosolic phospholipase A2; catalytic domain; Ca-dependent; cd07200
membrane-attack complex / perforin; smart00457
Regulator of G protein signaling (RGS) domain found in the RGS18 protein; cd08712
Regulator of G protein signaling (RGS) domain found in the RGS21 protein; cd08723
Regulator of G protein signaling (RGS) domain found in the RGS1 protein; cd08715
Regulator of G protein signaling (RGS) domain found in the RGS13 protein; cd08716
Regulator of G protein signaling (RGS) domain found in the RGS13 protein; cd08716
Regulator of G protein signaling (RGS) domain found in the RGS2 protein; cd08709
Cysteine peptidase C12 contains ubiquitin carboxyl-terminal hydrolase (UCH) families L1, L3, L5 and BAP1; cd02255
Cysteine peptidase C12 contains ubiquitin carboxyl-terminal hydrolase (UCH) families L1, L3, L5 and BAP1; cd02255
Cysteine peptidase C12 contains ubiquitin carboxyl-terminal hydrolase (UCH) families L1, L3, L5 and BAP1; cd02255
Cysteine peptidase C12 contains ubiquitin carboxyl-terminal hydrolase (UCH) families L1, L3, L5 and BAP1; cd02255
TROVE domain; pfam05731
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cd00198
TROVE domain; pfam05731
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cd00198
TROVE domain; pfam05731
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cd00198
TROVE domain; pfam05731
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cd00198
TROVE domain; pfam05731
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cd00198
Glutaredoxin (GRX) family, GRX human class 1 and 2 (h_1_2)-like subfamily; composed of proteins similar to human GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase; cd03419
Glutaredoxin (GRX) family, GRX human class 1 and 2 (h_1_2)-like subfamily; composed of proteins similar to human GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase; cd03419
Glutaredoxin (GRX) family, GRX human class 1 and 2 (h_1_2)-like subfamily; composed of proteins similar to human GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase; cd03419
RNA pol II accessory factor, Cdc73 family; pfam05179
Galactosyltransferase; pfam01762
Ion channel; pfam07885
Calcium-activated BK potassium channel alpha subunit; pfam03493
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
EEV Host range protein; Provisional
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cl00030
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cl00030
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; smart00799
dDENN domain; pfam03455
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; smart00799
dDENN domain; pfam03455
LIM domain; pfam00412
LIM domain; pfam00412
Homeobox domain; pfam00046
The first LIM domain of Lhx2; cd09469
The second LIM domain of Lhx2 and Lhx9 family; cd09377
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Catalytic domain of the Protein Serine/Threonine Kinases, Never In Mitosis gene A-related kinase 6 and 7; cd08224
Serine/Threonine protein kinases, catalytic domain; smart00220
Vacuolar (H+)-ATPase G subunit; pfam03179
Vacuolar (H+)-ATPase G subunit; cl03922
Protein tyrosine phosphatase N terminal; pfam12453
Protein tyrosine phosphatase N terminal; pfam12453
Leukocyte receptor CD45; pfam12567
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase N terminal; pfam12453
Leukocyte receptor CD45; pfam12567
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase N terminal; pfam12453
The DNA-binding domain of Lrh-1 like nuclear receptor family like is composed of two C4-type zinc fingers; cd07167
The ligand binding domain of the liver receptor homolog-1, a member of  nuclear receptor superfamily; cd07069
The DNA-binding domain of Lrh-1 like nuclear receptor family like is composed of two C4-type zinc fingers; cd07167
The ligand binding domain of the liver receptor homolog-1, a member of  nuclear receptor superfamily; cd07069
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Kinesin motor domain, KIF1_like proteins. KIF1A (Unc104) transports synaptic vesicles to the nerve terminal, KIF1B has been implicated in transport of mitochondria. Both proteins are expressed in neurons. This catalytic (head) domain has ATPase activity...; cd01365
Kinesin motor, catalytic domain. ATPase; smart00129
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
ATP synthase B/B' CF(0); cl07975
DEAD-box ATP-dependent RNA helicase; Provisional
HIT zinc finger; pfam04438
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
CAMSAP CH domain; pfam11971
Microtubule-binding calmodulin-regulated spectrin-associated; smart01051
7 transmembrane receptor (rhodopsin family); pfam00001
Domain of unknown function (DUF3338); pfam11819
Domain of unknown function (DUF3338); pfam11819
Kinesin motor domain, KIF4-like subfamily. Members of this group seem to perform a variety of functions, and have been implicated in neuronal organelle transport and chromosome segregation during mitosis. This catalytic (head) domain has ATPase activity...; cd01372
Kinesin motor, catalytic domain. ATPase; smart00129
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
Kinesin motor domain, KIF4-like subfamily. Members of this group seem to perform a variety of functions, and have been implicated in neuronal organelle transport and chromosome segregation during mitosis. This catalytic (head) domain has ATPase activity...; cd01372
Kinesin motor, catalytic domain. ATPase; smart00129
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
Kinesin motor domain, KIF4-like subfamily. Members of this group seem to perform a variety of functions, and have been implicated in neuronal organelle transport and chromosome segregation during mitosis. This catalytic (head) domain has ATPase activity...; cd01372
Kinesin motor, catalytic domain. ATPase; smart00129
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
Kinesin motor domain, KIF4-like subfamily. Members of this group seem to perform a variety of functions, and have been implicated in neuronal organelle transport and chromosome segregation during mitosis. This catalytic (head) domain has ATPase activity...; cd01372
Kinesin motor, catalytic domain. ATPase; smart00129
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Voltage gated calcium channel IQ domain; pfam08763
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
TMEM9; pfam05434
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin domain; cl11960
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Troponin; pfam00992
Troponin; pfam00992
Troponin; pfam00992
Troponin; pfam00992
Troponin; pfam00992
Troponin; pfam00992
Troponin; pfam00992
Troponin; pfam00992
Troponin; pfam00992
Pleckstrin homology (PH) domain; cd00821
The first LIM domain of Cysteine Rich Protein 1 (CRP1); cd09479
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
The first LIM domain of Cysteine Rich Protein 1 (CRP1); cd09479
The second LIM domain of Cysteine Rich Protein (CRP); cd09403
The first LIM domain of Cysteine Rich Protein 1 (CRP1); cd09479
The second LIM domain of Cysteine Rich Protein (CRP); cd09403
The first LIM domain of Cysteine Rich Protein 1 (CRP1); cd09479
The second LIM domain of Cysteine Rich Protein (CRP); cd09403
TATA element modulatory factor 1 TATA binding; pfam12325
ATPases associated with a variety of cellular activities; smart00382
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
TATA element modulatory factor 1 TATA binding; pfam12325
ATPases associated with a variety of cellular activities; smart00382
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
CAS/CSE protein involved in chromosome segregation [Cell division and chromosome partitioning]; COG5657
Importin-beta N-terminal domain; smart00913
Wnt and FGF inhibitory regulator; pfam13908
Tim17/Tim22/Tim23/Pmp24 family; cl02381
leukotriene A-4 hydrolase/aminopeptidase; TIGR02411
Peptidase M1 family contains leukotriene A4 hydrolase; cd09599
Leukotriene A4 hydrolase, C-terminal; pfam09127
Sterile alpha motif (SAM)/Pointed domain of ESE-1 like ETS transcriptional regulators; cd08537
erythroblast transformation specific domain; smart00413
Sterile alpha motif (SAM)/Pointed domain of ESE-1 like ETS transcriptional regulators; cd08537
erythroblast transformation specific domain; smart00413
7 transmembrane receptor (rhodopsin family); pfam00001
GTPase SAR1 and related small G proteins [General function prediction only]
Arf-like 9 (Arl9) and 10 (Arl10) GTPases; cd04159
GTPase SAR1 and related small G proteins [General function prediction only]
Arf-like 9 (Arl9) and 10 (Arl10) GTPases; cd04159
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
SH3 domain protein; TIGR04211
C2A domain first repeat present in Synaptotagmins 1, 5, 6, 9, and 10; cd08385
C2 domain second repeat present in Synaptotagmin 1; cd08402
C2A domain first repeat present in Synaptotagmins 1, 5, 6, 9, and 10; cd08385
C2 domain second repeat present in Synaptotagmin 1; cd08402
Small domain found in the jumonji family of transcription factors; smart00545
ARID/BRIGHT DNA binding domain; pfam01388
PHD-finger; pfam00628
JmjC domain, hydroxylase; pfam02373
C5HC2 zinc finger; pfam02928
PLU-1-like protein; pfam08429
PHD-finger; pfam00628
PHD-finger; pfam00628
Nucleotide exchange factor for Rab-like small GTPases (RabGEF), Mss4 type; RabGEF positely regulates the function of  Rab GTPase by promoting exchange of GDP for GTP; members of the Rab subfamily of Ras GTPases are important in vesicular transport; cd00246
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch domain; smart00612
Kelch domain; smart00612
Kelch domain; smart00612
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch motif; pfam01344
Haemolysin-III related; pfam03006
NADH-cytochrome B5 reductase; Provisional
Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a...; cd06183
SAM domain of liprin-alpha1,2,3,4 proteins repeat 1; cd09562
Sterile alpha motif; smart00454
SAM domain of liprin-alpha1,2,3,4 proteins repeat 2; cd09565
Sterile alpha motif; smart00454
SAM domain of liprin-alpha1,2,3,4 proteins repeat 3; cd09568
Sterile alpha motif; smart00454
Myogenic Basic domain; pfam01586
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Immunoglobulin domain; cl11960
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Glyco_18 domain; smart00636
This conserved domain family includes a large number of catalytically inactive chitinase-like lectins (chitolectins) including YKL-39, YKL-40 (HCGP39), YM1, oviductin, and AMCase (acidic mammalian chitinase), as well as catalytically active...; cd02872
Glyco_18 domain; smart00636
This conserved domain family includes a large number of catalytically inactive chitinase-like lectins (chitolectins) including YKL-39, YKL-40 (HCGP39), YM1, oviductin, and AMCase (acidic mammalian chitinase), as well as catalytically active...; cd02872
Chitin-binding domain type 2; smart00494
Glyco_18 domain; smart00636
This conserved domain family includes a large number of catalytically inactive chitinase-like lectins (chitolectins) including YKL-39, YKL-40 (HCGP39), YM1, oviductin, and AMCase (acidic mammalian chitinase), as well as catalytically active...; cd02872
Chitin-binding domain type 2; smart00494
Glyco_18 domain; smart00636
This conserved domain family includes a large number of catalytically inactive chitinase-like lectins (chitolectins) including YKL-39, YKL-40 (HCGP39), YM1, oviductin, and AMCase (acidic mammalian chitinase), as well as catalytically active...; cd02872
Chitin-binding domain type 2; smart00494
BTG family; pfam07742
Leucine rich repeat N-terminal domain; smart00013
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat N-terminal domain; smart00013
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat N-terminal domain; smart00013
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
plasma-membrane calcium-translocating P-type ATPase; TIGR01517
Cation transporter/ATPase, N-terminus; pfam00690
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
Cation transporting ATPase, C-terminus; pfam00689
Plasma membrane calcium transporter ATPase C terminal; pfam12424
plasma-membrane calcium-translocating P-type ATPase; TIGR01517
Cation transporter/ATPase, N-terminus; pfam00690
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
Cation transporting ATPase, C-terminus; pfam00689
Plasma membrane calcium transporter ATPase C terminal; pfam12424
BED zinc finger; smart00614
BED zinc finger; smart00614
hAT family dimerisation domain; pfam05699
Sm protein E; cd01718
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
choline kinase
Ethanolamine kinase (ETNK) in eukaryotes. ETNK is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and...; cd05157
A1 Propeptide; pfam07966
Renin stimulates production of angiotensin and thus affects blood pressure; cd05487
Eukaryotic aspartyl protease; pfam00026
Got1/Sft2-like family; cl02130
Pleckstrin homology (PH) domain; cd00821
eIF2-alpha phosphatase phosphorylation constitutive repressor; pfam10472
Phosphatase-1 catalytic subunit binding region; pfam10488
PI3-kinase family, ras-binding domain; pfam00794
C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks); cd04012
Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general,  class II PI3-kinases...; cd00869
Phosphoinositide 3-kinase (PI3K), class II, beta isoform, catalytic domain; The PI3K catalytic domain family is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein...; cd00895
Phosphoinositide 3-kinase, catalytic domain; smart00146
The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases; cd07290
C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks); cd08381
SWIB/MDM2 domain; pfam02201
Zn-finger in Ran binding protein and others; pfam00641
Zinc finger, C3HC4 type (RING finger); pfam13920
Zinc finger, C3HC4 type (RING finger); pfam13923
SWIB/MDM2 domain; pfam02201
Zn-finger in Ran binding protein and others; pfam00641
Zinc finger, C3HC4 type (RING finger); pfam13920
Zinc finger, C3HC4 type (RING finger); pfam13923
Zinc finger, C3HC4 type (RING finger); pfam13920
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF); cd05875
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM); cd05731
Immunoglobulin I-set domain; pfam07679
Fourth immunoglobulin (Ig)-like domain of L1, Ng-CAM (Neuron-glia CAM cell adhesion molecule), and NrCAM (Ng-CAM-related); cd04978
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
C-terminal domain of Fibronectin type III; pfam13882
Immunoglobulin I-set domain; pfam07679
Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF); cd05875
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM); cd05731
Immunoglobulin I-set domain; pfam07679
Fourth immunoglobulin (Ig)-like domain of L1, Ng-CAM (Neuron-glia CAM cell adhesion molecule), and NrCAM (Ng-CAM-related); cd04978
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
C-terminal domain of Fibronectin type III; pfam13882
Immunoglobulin I-set domain; pfam07679
Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF); cd05875
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM); cd05731
Immunoglobulin I-set domain; pfam07679
Fourth immunoglobulin (Ig)-like domain of L1, Ng-CAM (Neuron-glia CAM cell adhesion molecule), and NrCAM (Ng-CAM-related); cd04978
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
C-terminal domain of Fibronectin type III; pfam13882
Immunoglobulin I-set domain; pfam07679
Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF); cd05875
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM); cd05731
Immunoglobulin I-set domain; pfam07679
Fourth immunoglobulin (Ig)-like domain of L1, Ng-CAM (Neuron-glia CAM cell adhesion molecule), and NrCAM (Ng-CAM-related); cd04978
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
C-terminal domain of Fibronectin type III; pfam13882
Immunoglobulin I-set domain; pfam07679
Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF); cd05875
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM); cd05731
Immunoglobulin I-set domain; pfam07679
Fourth immunoglobulin (Ig)-like domain of L1, Ng-CAM (Neuron-glia CAM cell adhesion molecule), and NrCAM (Ng-CAM-related); cd04978
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF); cd05875
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM); cd05731
Immunoglobulin I-set domain; pfam07679
Fourth immunoglobulin (Ig)-like domain of L1, Ng-CAM (Neuron-glia CAM cell adhesion molecule), and NrCAM (Ng-CAM-related); cd04978
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
First Ig domain of contactin-2; cd05850
Second Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins; cd05727
Third Ig domain of contactin; cd04968
Immunoglobulin I-set domain; pfam07679
Fourth Ig domain of the neural cell adhesion molecule contactin-2 and similar proteins; cd05728
Fifth Ig domain of contactin; cd04969
Immunoglobulin I-set domain; pfam07679
Sixth Ig domain of contactin-2; cd05854
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Predicted transmembrane and coiled-coil 2 protein; pfam10267
Predicted transmembrane and coiled-coil 2 protein; pfam10267
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Kelch domain; smart00612
Kelch motif; pfam01344
Galactose oxidase, central domain; cl02701
Kelch motif; pfam13964
Kelch domain; smart00612
LEM domain; pfam03020
LEM domain; pfam03020
Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-3 kinase; cd07871
cyclin-dependent kinase A; Provisional
Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-3 kinase; cd07871
cyclin-dependent kinase A; Provisional
Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-3 kinase; cd07871
cyclin-dependent kinase A; Provisional
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
erythroblast transformation specific domain; smart00413
erythroblast transformation specific domain; smart00413
GPH family sucrose/H+ symporter; TIGR01301
Rab family protein; Provisional
Rab GTPase families 18 (Rab18) and 32 (Rab32); cd04107
Rab family protein; Provisional
Rab GTPase families 18 (Rab18) and 32 (Rab32); cd04107
Rab family protein; Provisional
Rab GTPase families 18 (Rab18) and 32 (Rab32); cd04107
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Divalent cation transporter; pfam01769
Divalent cation transporter; cl00786
hypothetical protein; Provisional
M20 Peptidase, carboxypeptidase yscS; cd05674
Sulfate transporter N-terminal domain with GLY motif; pfam13792
Sulfate transporter family; pfam00916
Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; cd07042
Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; cd07042
Sulfate transporter N-terminal domain with GLY motif; pfam13792
Sulfate transporter family; pfam00916
Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; cd07042
Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; cd07042
7 transmembrane receptor (rhodopsin family); pfam00001
A1 Propeptide; pfam07966
Eukaryotic aspartyl protease; pfam00026
Cellular and retroviral pepsin-like aspartate proteases; cl11403
A1 Propeptide; pfam07966
Eukaryotic aspartyl protease; pfam00026
Cathepsin E, non-lysosomal aspartic protease; cd05486
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 2; cd07682
RhoGAP_srGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs...; cd04383
GTPase-activator protein for Rho-like GTPases; smart00324
Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3; cd11955
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 2; cd07682
RhoGAP_srGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs...; cd04383
GTPase-activator protein for Rho-like GTPases; smart00324
Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3; cd11955
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 2; cd07682
RhoGAP_srGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs...; cd04383
GTPase-activator protein for Rho-like GTPases; smart00324
Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3; cd11955
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Catalytic domain of Protein Kinases; cd00180
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Ubiquitin-like proteins; cl00155
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Ubiquitin-like proteins; cl00155
Ubiquitin-like proteins; cl00155
N-terminal domain of eIF2D and related proteins; cd11610
Predicted RNA-binding protein (contains PUA domain) [Translation, ribosomal structure and biogenesis]
PUA domain; cl00607
C-terminal domain of eIF2D and related proteins; cd11608
N-terminal domain of eIF2D and related proteins; cd11610
Predicted RNA-binding protein (contains PUA domain) [Translation, ribosomal structure and biogenesis]
PUA domain; cl00607
C-terminal domain of eIF2D and related proteins; cd11608
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Interleukin-10 family; smart00188
Il-24-like protein; Provisional
Il-24-like protein; Provisional
Interleukin 10; cl02501
Il-24-like protein; Provisional
Il-24-like protein; Provisional
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin V-Type; smart00406
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin V-Type; smart00406
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin V-Type; smart00406
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin V-Type; smart00406
Predicted cysteine protease (OTU family) [Posttranslational modification, protein turnover, chaperones]
OTU-like cysteine protease; pfam02338
6-phosphofructo-2-kinase; pfam01591
AAA domain; pfam13671
Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; cd07067
6-phosphofructo-2-kinase; pfam01591
AAA domain; pfam13671
Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; cd07067
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Putative binding domain; pfam13900
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
secreted complement-binding protein; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CD34/Podocalyxin family; pfam06365
CD34/Podocalyxin family; pfam06365
The Sema domain, a protein interacting module, of Plexin A2; cd11272
semaphorin domain; smart00630
Plexin repeat; pfam01437
Plexin repeat; pfam01437
First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present...; cd01180
Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present...; cd01179
Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present...; cd01181
IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the...; cd00603
Plexin cytoplasmic RasGAP domain; pfam08337
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Laminin N-terminal domain (domain VI); smart00136
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
ATP synthase B/B' CF(0); cl07975
Laminin N-terminal domain (domain VI); smart00136
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
ATP synthase B/B' CF(0); cl07975
Laminin N-terminal domain (domain VI); smart00136
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
ATP synthase B/B' CF(0); cl07975
11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs; cd05332
Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) [Cell envelope biogenesis, outer membrane]; COG3967
11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs; cd05332
Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) [Cell envelope biogenesis, outer membrane]; COG3967
11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs; cd05332
Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) [Cell envelope biogenesis, outer membrane]; COG3967
chromosome segregation protein SMC, common bacterial type; TIGR02168
Interferon Regulatory Factor (IRF); also known as tryptophan pentad repeat. The family of IRF transcription factors is important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. The...; cd00103
Interferon-regulatory factor 3; pfam10401
Interferon-regulatory factor 3; pfam10401
Protein of unknown function (DUF1253); pfam06862
C2A domain first repeat present in Synaptotagmins 14 and 16; cd08389
C2 domain second repeat present in Synaptotagmins 14 and 16; cd08408
C2A domain first repeat present in Synaptotagmins 14 and 16; cd08389
C2 domain second repeat present in Synaptotagmins 14 and 16; cd08408
C2A domain first repeat present in Synaptotagmins 14 and 16; cd08389
C2 domain second repeat present in Synaptotagmins 14 and 16; cd08408
C2A domain first repeat present in Synaptotagmins 14 and 16; cd08389
C2 domain second repeat present in Synaptotagmins 14 and 16; cd08408
C2A domain first repeat present in Synaptotagmins 14 and 16; cd08389
C2 domain second repeat present in Synaptotagmins 14 and 16; cd08408
SERTA motif; pfam06031
MBOAT, membrane-bound O-acyltransferase family; pfam03062
MBOAT, membrane-bound O-acyltransferase family; pfam03062
MBOAT, membrane-bound O-acyltransferase family; pfam03062
MBOAT, membrane-bound O-acyltransferase family; pfam03062
MBOAT, membrane-bound O-acyltransferase family; pfam03062
MBOAT, membrane-bound O-acyltransferase family; pfam03062
PAS domain; pfam13426
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
Ion channel; pfam07885
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
PAS domain; pfam13426
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
Ion transport protein; pfam00520
Ion channel; pfam07885
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
ELM2 domain; pfam01448
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cl15779
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
ELM2 domain; pfam01448
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cl15779
ELM2 domain; pfam01448
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cl15779
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
ELM2 domain; pfam01448
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cl15779
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
TRAF-type zinc finger; pfam02176
TRAF-type zinc finger; pfam02176
Biogenesis of lysosome-related organelles complex-1 subunit 2; pfam10046
Tumor Necrosis Factor Receptor (TNFR)-Associated Factor (TRAF) family, TRAF5 subfamily, TRAF domain, C-terminal MATH subdomain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of...; cd03780
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
TRAF-type zinc finger; pfam02176
TRAF-type zinc finger; pfam02176
Biogenesis of lysosome-related organelles complex-1 subunit 2; pfam10046
Tumor Necrosis Factor Receptor (TNFR)-Associated Factor (TRAF) family, TRAF5 subfamily, TRAF domain, C-terminal MATH subdomain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of...; cd03780
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
TRAF-type zinc finger; pfam02176
TRAF-type zinc finger; pfam02176
Biogenesis of lysosome-related organelles complex-1 subunit 2; pfam10046
Tumor Necrosis Factor Receptor (TNFR)-Associated Factor (TRAF) family, TRAF5 subfamily, TRAF domain, C-terminal MATH subdomain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of...; cd03780
Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; COG1230
Cation efflux family; pfam01545
Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; COG1230
Cation efflux family; pfam01545
Catalytic domain of the Protein Serine/Threonine Kinase, Never In Mitosis gene A-related kinase 2; cd08217
Serine/Threonine protein kinases, catalytic domain; smart00220
Putative binding domain; pfam13900
Catalytic domain of the Protein Serine/Threonine Kinase, Never In Mitosis gene A-related kinase 2; cd08217
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, Never In Mitosis gene A-related kinase 2; cd08217
Serine/Threonine protein kinases, catalytic domain; smart00220
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; cd07990
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Protein phosphatase 2A regulatory B subunit (B56 family); pfam01603
Protein phosphatase 2A regulatory B subunit (B56 family); pfam01603
Cytochrome b5-like Heme/Steroid binding domain; pfam00173
basic region leucin zipper; smart00338
basic region leucin zipper; smart00338
basic region leucin zipper; smart00338
basic region leucin zipper; smart00338
Protein of unknown function (DUF3699); pfam12480
basic region leucin zipper; smart00338
Kinetochore protein Mis14 like; pfam08641
Kinetochore protein Mis14 like; pfam08641
TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; cd01310
TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; cd01310
TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; cd01310
TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; cd01310
TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; cd01310
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Major Facilitator Superfamily; pfam07690
Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; cl00490
The phosphoinositide binding Phox Homology domain of RPK118-like proteins; cd07287
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This MIT domain sub-family is found in sorting nexin 15 and related proteins. The molecular function of the MIT domain is unclear; cd02677
Microtubule Interacting and Trafficking molecule domain; smart00745
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinases, RPK118 and similar proteins; cd05576
The Phox Homology domain, a phosphoinositide binding module; cl02563
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This MIT domain sub-family is found in sorting nexin 15 and related proteins. The molecular function of the MIT domain is unclear; cd02677
Microtubule Interacting and Trafficking molecule domain; smart00745
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinases, RPK118 and similar proteins; cd05576
Homeobox prospero-like protein (PROX1); pfam05044
Homeobox prospero-like protein (PROX1); pfam05044
MYND finger; pfam01753
SET domain; pfam00856
Tetratricopeptide repeat; pfam13424
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
Pleckstrin homology-like domain; cl00273
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Cenp-F N-terminal domain; pfam10481
chromosome segregation protein SMC, common bacterial type; TIGR02168
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; pfam10473
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; pfam10473
Rb-binding domain of kinetochore protein Cenp-F/LEK1; pfam10490
Ion channel; pfam07885
Ion channel; pfam07885
Ion channel; pfam07885
Ion channel; pfam07885
Ion channel; pfam07885
Ion channel; pfam07885
K+ channel tetramerisation domain; pfam02214
LamG-like jellyroll fold domain; smart00560
Laminin N-terminal (Domain VI); cl02806
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; smart00060
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
LamG-like jellyroll fold domain; smart00560
Laminin N-terminal (Domain VI); cl02806
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers; cd07170
The ligand binding domain of estrogen receptor-related nuclear receptors; cd06946
DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers; cd07170
The ligand binding domain of estrogen receptor-related nuclear receptors; cd06946
DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers; cl02596
The ligand binding domain of estrogen receptor-related nuclear receptors; cd06946
DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers; cd07170
The ligand binding domain of estrogen receptor-related nuclear receptors; cd06946
DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers; cd07170
The ligand binding domain of estrogen receptor-related nuclear receptors; cd06946
DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers; cd07170
The ligand binding domain of estrogen receptor-related nuclear receptors; cd06946
DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers; cd07170
The ligand binding domain of estrogen receptor-related nuclear receptors; cd06946
DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers; cd07170
The ligand binding domain of estrogen receptor-related nuclear receptors; cd06946
DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers; cd07170
The ligand binding domain of estrogen receptor-related nuclear receptors; cd06946
DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers; cd07170
The ligand binding domain of estrogen receptor-related nuclear receptors; cd06946
DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers; cd07170
The ligand binding domain of estrogen receptor-related nuclear receptors; cd06946
DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers; cd07170
The ligand binding domain of estrogen receptor-related nuclear receptors; cd06946
DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers; cd07170
The ligand binding domain of estrogen receptor-related nuclear receptors; cd06946
DNA-binding domain of estrogen related receptors (ERR) is composed of two C4-type zinc fingers; cd07170
The ligand binding domain of estrogen receptor-related nuclear receptors; cd06946
DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers; cl02596
The ligand binding domain of estrogen receptor-related nuclear receptors; cd06946
The ligand binding domain of estrogen receptor-related nuclear receptors; cd06946
G-patch domain; pfam01585
IQ calmodulin-binding motif; cl15479
Rrp15p; pfam07890
TGF-beta propeptide; pfam00688
Transforming growth factor beta like domain; pfam00019
TGF-beta propeptide; pfam00688
Transforming growth factor beta like domain; pfam00019
Phospholipase/Carboxylesterase; pfam02230
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; COG1230
Cation efflux family; pfam01545
Cation efflux family; pfam01545
Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; COG1230
glutamate-tRNA ligase
Glutathione S-transferase C-terminal-like, alpha helical domain of bifunctional Glutamyl-Prolyl-tRNA synthetase; cd10309
nucleotidyl transferase superfamily; cl00015
catalytic core domain of glutaminyl-tRNA synthetase; cd00807
tRNA synthetases class I (E and Q), anti-codon binding domain; pfam03950
WEPRS_RNA binding domain. This short RNA-binding domain is found in several higher eukaryote aminoacyl-tRNA synthetases (aaRSs). It is found in multiple copies in eukaryotic bifunctional glutamyl-prolyl-tRNA synthetases (EPRS) in a region that separates...; cd00936
WEPRS_RNA binding domain. This short RNA-binding domain is found in several higher eukaryote aminoacyl-tRNA synthetases (aaRSs). It is found in multiple copies in eukaryotic bifunctional glutamyl-prolyl-tRNA synthetases (EPRS) in a region that separates...; cd00936
WEPRS_RNA binding domain. This short RNA-binding domain is found in several higher eukaryote aminoacyl-tRNA synthetases (aaRSs). It is found in multiple copies in eukaryotic bifunctional glutamyl-prolyl-tRNA synthetases (EPRS) in a region that separates...; cd00936
prolyl-tRNA synthetase; Provisional
Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of...; cd00778
ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; cd00862
IPPase; Inositol polyphosphate-1-phosphatase, a member of the Mg++ dependent family of inositol monophosphatase-like domains, hydrolyzes the 1' position phosphate from inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate. Members in this group may...; cd01640
isoleucyl-tRNA synthetase; Reviewed; PRK05743
catalytic core domain of isoleucyl-tRNA synthetases; cd00818
catalytic core domain of isoleucyl-tRNA synthetases; cd00818
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; cd07960
Zinc finger found in FPG and IleRS; pfam06827
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Kinase associated domain 1; pfam02149
MOSC N-terminal beta barrel domain; pfam03476
Uncharacterized Fe-S protein [General function prediction only]
MOSC domain; pfam03473
MOSC N-terminal beta barrel domain; pfam03476
Uncharacterized Fe-S protein [General function prediction only]
MOSC domain; pfam03473
Homeodomain-containing transcription factor [Transcription]
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by...; cd01446
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
Folate receptor family; pfam03024
dehydrogenase, PQQ-dependent, s-GDH family; TIGR03606
Src Homology 3 domain of Melanoma Inhibitory Activity 3 protein; cd11893
C2 domain of Aida; pfam08910
Cytoskeletal adhesion; pfam14186
Protein-interacting Bro1-like domain of human Brox1 and related proteins; cd09243
BRO1-like domain; smart01041
Protein export membrane protein; cl14618
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
TIR domain; pfam01582
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Sushi domain (SCR repeat); pfam00084
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction; cd00044
Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are...; cd00214
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
centrin; Provisional
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction; cd00044
Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are...; cd00214
EF-hand domain pair; pfam13833
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction; cd00044
Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are...; cd00214
EF-hand domain pair; pfam13833
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
Protein-interacting V-domain of mammalian Alix and related domains; cl14654
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Src Homology 3 (SH3) domain of Apoptosis Stimulating of p53 protein 2; cd11953
Protein-interacting V-domain of mammalian Alix and related domains; cl14654
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Src Homology 3 (SH3) domain of Apoptosis Stimulating of p53 protein 2; cd11953
F-box domain; pfam00646
F-box domain; cl02535
sphingolipid delta-4 desaturase
Sphingolipid Delta4-desaturase (DES); pfam08557
The Delta4-sphingolipid Fatty Acid Desaturase (Delta4-sphingolipid-FADS)-like CD includes the integral-membrane enzymes, dihydroceramide Delta-4 desaturase, involved in the synthesis of sphingosine; and the human membrane fatty acid (lipid) desaturase; cd03508
ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; COG0464
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; COG0464
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; COG0464
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; COG0464
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Cornichon protein; pfam03311
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Cornichon protein; pfam03311
Dynein heavy chain, N-terminal region 2; pfam08393
Hydrolytic ATP binding site of dynein motor region D1; pfam12774
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Microtubule-binding stalk of dynein motor; pfam12777
ATP-binding dynein motor region D5; pfam12781
Dynein heavy chain and region D6 of dynein motor; pfam03028
Lamin-B receptor of TUDOR domain; pfam09465
Phospholipid methyltransferase; cl00763
Lamin-B receptor of TUDOR domain; pfam09465
Phospholipid methyltransferase; cl00763
Enabled-VASP-type homology (EVH1) domain; cd01207
VASP tetramerisation domain; pfam08776
Enabled-VASP-type homology (EVH1) domain; cd01207
VASP tetramerisation domain; pfam08776
Signal recognition particle 9 kDa protein (SRP9); pfam05486
Signal recognition particle 9 kDa protein (SRP9); pfam05486
Epoxide hydrolase N terminus; pfam06441
alpha/beta hydrolase fold; pfam00561
Epoxide hydrolase N terminus; pfam06441
alpha/beta hydrolase fold; pfam00561
Late exocytosis, associated with Golgi transport; pfam13967
Domain of unknown function DUF221; pfam02714
TGF-beta propeptide; pfam00688
Transforming growth factor beta like domain; cl02510
pyrroline-5-carboxylate reductase
pyrroline-5-carboxylate reductase; Reviewed
TGF-beta propeptide; pfam00688
Transforming growth factor beta like domain; cl02510
TGF-beta propeptide; pfam00688
Transforming growth factor beta like domain; cl02510
Telomere stability and silencing; pfam13019
Telomere stability C-terminal; pfam13297
histone H3; Provisional
Acyl CoA binding protein; pfam00887
Golgi-dynamics membrane-trafficking; pfam13897
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
DIRP; pfam06584
DIRP; pfam06584
DIRP; pfam06584
poly [ADP-ribose] polymerase; Provisional
Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region; pfam00645
Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region; pfam00645
PADR1 (NUC008) domain; pfam08063
BRCA1 C Terminus (BRCT) domain; pfam00533
WGR domain of poly(ADP-ribose) polymerase 1 and similar proteins; cd08001
Poly(ADP-ribose) polymerase (parp) catalytic domain catalyses the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins,  which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a...; cd01437
Inositol polyphosphate kinase; pfam03770
Presenilin; pfam01080
Presenilin; pfam01080
Predicted unusual protein kinase [General function prediction only]; COG0661
ABC1 family; pfam03109
Catalytic domain of Myotonic Dystrophy protein kinase-like Protein Serine/Threonine Kinases; cd05597
Serine/Threonine protein kinases, catalytic domain; smart00220
ATPase involved in DNA repair [DNA replication, recombination, and repair]; COG0419
DMPK coiled coil domain like; pfam08826
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
MRCK (myotonic dystrophy-related Cdc42-binding kinase)  pleckstrin homology (PH) domain; cd01243
CNH domain; pfam00780
PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the...; cd00132
Catalytic domain of Myotonic Dystrophy protein kinase-like Protein Serine/Threonine Kinases; cd05597
Serine/Threonine protein kinases, catalytic domain; smart00220
ATPase involved in DNA repair [DNA replication, recombination, and repair]; COG0419
DMPK coiled coil domain like; pfam08826
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
MRCK (myotonic dystrophy-related Cdc42-binding kinase)  pleckstrin homology (PH) domain; cd01243
CNH domain; pfam00780
PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the...; cd00132
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
JmjC domain, hydroxylase; pfam02373
JmjC domain, hydroxylase; pfam02373
SNARE domain; pfam05739
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
wnt family; pfam00110
found in Wnt-1; smart00097
wnt family; pfam00110
found in Wnt-1; smart00097
GTPase SAR1 and related small G proteins [General function prediction only]
ADP-ribosylation factor-1 (Arf1) and ADP-ribosylation factor-5 (Arf5); cd04150
GTPase SAR1 and related small G proteins [General function prediction only]
ADP-ribosylation factor-1 (Arf1) and ADP-ribosylation factor-5 (Arf5); cd04150
GTPase SAR1 and related small G proteins [General function prediction only]
ADP-ribosylation factor-1 (Arf1) and ADP-ribosylation factor-5 (Arf5); cd04150
GTPase SAR1 and related small G proteins [General function prediction only]
ADP-ribosylation factor-1 (Arf1) and ADP-ribosylation factor-5 (Arf5); cd04150
Kinase phosphorylation protein; pfam10159
Mitochondrial ribosomal protein L55; pfam09776
Mitochondrial ribosomal protein L55; pfam09776
Mitochondrial ribosomal protein L55; pfam09776
Mitochondrial ribosomal protein L55; pfam09776
Mitochondrial ribosomal protein L55; pfam09776
Mitochondrial ribosomal protein L55; pfam09776
Mitochondrial ribosomal protein L55; pfam09776
Mitochondrial ribosomal protein L55; pfam09776
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
Connexin; pfam00029
Gap junction channel protein cysteine-rich domain; pfam10582
Predicted aminomethyltransferase related to GcvT [General function prediction only]
folate-binding protein YgfZ; TIGR03317
Glycine cleavage T-protein C-terminal barrel domain; pfam08669
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin; smart00409
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin like; smart00410
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin domain; cd00096
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin like; smart00410
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Src homology 3 domain of Obscurin and similar proteins; cd12025
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Catalytic domain of Protein Kinases; cd00180
Serine/Threonine protein kinases, catalytic domain; smart00220
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin like; smart00410
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin C-2 Type; smart00408
Immunoglobulin; smart00409
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin like; smart00410
Immunoglobulin; smart00409
Immunoglobulin; smart00409
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Src homology 3 domain of Obscurin and similar proteins; cd12025
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Catalytic domain of Protein Kinases; cd00180
Serine/Threonine protein kinases, catalytic domain; smart00220
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin like; smart00410
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin C-2 Type; smart00408
Immunoglobulin like; smart00410
Immunoglobulin like; smart00410
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin; smart00409
Immunoglobulin like; smart00410
Immunoglobulin; smart00409
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin (Ig)-like domain of semaphorin; cd04979
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Src homology 3 domain of Obscurin and similar proteins; cd12025
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
SPRY-associated domain; pfam13765
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
associated with SPRY domains; smart00589
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
associated with SPRY domains; smart00589
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
histone H3; Provisional
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cd00074
Histone H2B; smart00427
Ring finger; smart00184
GTPase SAR1 and related small G proteins [General function prediction only]
Wnt-1 responsive Cdc42 homolog (Wrch-1) is a Rho family GTPase similar to Cdc42; cd04130
Rab family protein; Provisional
Rab GTPase family 4 (Rab4); cd04113
Actin; pfam00022
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Nup133 N terminal like; pfam08801
Non-repetitive/WGA-negative nucleoporin C-terminal; pfam03177
ABC transporter, permease/ATP-binding protein; TIGR02204
ABC transporter transmembrane region; pfam00664
MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1.  In fact, the...; cd03249
TAF5_NTD2 is the second conserved N-terminal region of TATA Binding Protein (TBP) Associated Factor 5 (TAF5), involved in forming Transcription Factor IID (TFIID); cd08044
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
TAF5_NTD2 is the second conserved N-terminal region of TATA Binding Protein (TBP) Associated Factor 5 (TAF5), involved in forming Transcription Factor IID (TFIID); cd08044
Urb2/Npa2 family; pfam10441
pp-GalNAc-T initiates the formation of mucin-type O-linked glycans; cd02510
Ricin-type beta-trefoil; smart00458
Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; cd00161
Transposase IS4; pfam13843
COG (conserved oligomeric Golgi) complex component, COG2; pfam06148
Domain of unknown function (DUF3510); pfam12022
COG (conserved oligomeric Golgi) complex component, COG2; pfam06148
Domain of unknown function (DUF3510); pfam12022
Angiotensinogen is part of the renin-angiotensin system (RAS), which plays an important role in blood pressure regulation, renal haemodynamics, fluid and electrolyte homeostasis. It is also involved in normal and abnormal growth processes. The growth...; cd02054
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction; cd00044
Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are...; cd00214
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction; cd00044
Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are...; cd00214
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
TPR repeat; pfam13414
Arv1-like family; pfam04161
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cl15348
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
SPRY-associated domain; cl02686
SPRY domain; pfam00622
Glycerol-3-phosphate O-acyltransferase [Lipid metabolism]; COG2937
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; cd07993
Vps51/Vps67; pfam08700
Exocyst complex 84-kDa subunit Pleckstrin Homology (PH) domain; cd01226
SprT homologues; smart00731
SprT-like family; pfam10263
Rad18-like CCHC zinc finger; smart00734
SprT homologues; smart00731
SprT-like family; pfam10263
SprT homologues; cl01182
SprT-like family; pfam10263
MYND finger; pfam01753
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam13640
Translin family; pfam01997
Putative binding domain; pfam13900
Rap/ran-GAP; pfam02145
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Domain of unknown function (DUF3401); pfam11881
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Pecanex protein (C-terminus); pfam05041
Src Homology 3 domain of Mixed Lineage Kinase 4; cd12058
Tyrosine kinase, catalytic domain; smart00219
Protein Kinases, catalytic domain; cl09925
Ion channel; pfam07885
Ion channel; pfam07885
Cytochrome c oxidase subunit VIb. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; cd00926
Cytochrome c oxidase subunit VIb. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; cd00926
SpoU rRNA Methylase family; pfam00588
Interferon regulatory factor 2-binding protein zinc finger; pfam11261
Interferon regulatory factor 2-binding protein zinc finger; pfam11261
mitochondrial import receptor subunit translocase of outer membrane 20 kDa subunit; TIGR00985
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Tudor domain; smart00333
RBB1NT (NUC162) domain; pfam08169
ARID/BRIGHT DNA binding domain; smart01014
Tudor domain; smart00333
RBB1NT (NUC162) domain; pfam08169
ARID/BRIGHT DNA binding domain; smart01014
RNA binding activity-knot of a chromodomain; pfam11717
Tudor domain; smart00333
RBB1NT (NUC162) domain; pfam08169
ARID/BRIGHT DNA binding domain; smart01014
RNA binding activity-knot of a chromodomain; pfam11717
Trans-Isoprenyl Diphosphate Synthases, head-to-tail; cd00685
Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; COG0142
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; smart01052
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine Rich repeats (2 copies); pfam12799
Ubiquitin-like proteins; cl00155
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; smart01052
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine Rich repeats (2 copies); pfam12799
Ubiquitin-like proteins; cl00155
Galactosyltransferase; cl09537
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors; cd00068
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors; cd00068
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors; cd00068
BEACH (Beige and Chediak-Higashi) domains, implicated in membrane trafficking,  are present in a family of proteins conserved throughout eukaryotes. This group contains human lysosomal trafficking regulator (LYST), LPS-responsive and beige-like anchor; cd06071
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Extracellular domain of unknown function in nidogen (entactin) and hypothetical proteins; smart00539
EGF domain; pfam12947
Nidogen, G2 domain; Nidogen is an important component of the basement membrane, an extracellular sheet-like matrix. Nidogen is a multifunctional protein that interacts with many other basement membrane proteins, like collagen, perlecan, lamin, and has a...; cd00255
EGF domain; pfam12947
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
EGF domain; pfam12947
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases; cd00191
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein-receptor YWTD domain; smart00135
EGF domain; pfam12947
Undecaprenyl-phosphate galactose phosphotransferase, WbaP; TIGR03022
Endoplasmic Reticulum Oxidoreductin 1 (ERO1); pfam04137
Death domain; pfam00531
Death domain; pfam00531
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
U3 small nucleolar RNA-associated protein 10; pfam12397
BP28CT (NUC211) domain; smart01036
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeat; pfam00435
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13833
Ca2+ insensitive EF hand; pfam08726
B12-dependent methionine synthase; Provisional; PRK09490
Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; COG0646
MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; cd00740
B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); cd02069
Vitamin B12 dependent methionine synthase, activation domain; pfam02965
Inositol 1,4,5-trisphosphate/ryanodine receptor; pfam08709
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
MIR domain; pfam02815
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
RIH domain; pfam01365
SPRY domain; pfam00622
RyR domain; pfam02026
RyR domain; pfam02026
Domain in SPla and the RYanodine Receptor; smart00449
SPRY domain; pfam00622
RIH domain; pfam01365
RyR domain; pfam02026
RyR domain; pfam02026
RyR and IP3R Homology associated; pfam08454
Putative motility protein; pfam14070
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Ryanodine Receptor TM 4-6; pfam06459
Ryanodine Receptor TM 4-6; pfam06459
P or trefoil or TFF domain; Trefoil factor family domain peptides are mucin-associated molecules, largely found in epithelia of gastrointestinal tissues. Function is not known but it was originally identified from mucosal tissues, where it may have a...; cd00111
Zona pellucida (ZP) domain; smart00241
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Formin Homology 2 Domain; pfam02181
Formin Homology 2 Domain; smart00498
DAN domain; pfam03045
DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain; cd04450
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors; cd00068
Regulator of G protein signaling (RGS) domain found in the R7 subfamily of proteins; cd08705
fumarate hydratase; Reviewed; PRK00485
Class II fumarases; cd01362
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; COG0654
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
7 transmembrane receptor (rhodopsin family); pfam00001
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
flap structure-specific endonuclease; TIGR03674
PIN domain of Exonuclease-1, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs; cd09857
H3TH domain of Exonuclease-1, a structure-specific, divalent-metal-ion dependent, 5' nuclease; cd09908
flap structure-specific endonuclease; TIGR03674
PIN domain of Exonuclease-1, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs; cd09857
H3TH domain of Exonuclease-1, a structure-specific, divalent-metal-ion dependent, 5' nuclease; cd09908
flap structure-specific endonuclease; TIGR03674
PIN domain of Exonuclease-1, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs; cd09857
H3TH domain of Exonuclease-1, a structure-specific, divalent-metal-ion dependent, 5' nuclease; cd09908
Ubiquitin domain of GABA-receptor-associated protein; cd01611
phospholipase-D-like protein; Provisional
Putative catalytic domain, repeat 1, of inactive veterbrate phospholipase PLD5; cd09146
Putative catalytic domain, repeat 2, of inactive veterbrate phospholipase PLD5; cd09149
phospholipase-D-like protein; Provisional
Putative catalytic domain, repeat 1, of inactive veterbrate phospholipase PLD5; cd09146
Putative catalytic domain, repeat 2, of inactive veterbrate phospholipase PLD5; cd09149
Catalytic domain of phospholipase D superfamily proteins; cl15239
Catalytic domain of phospholipase D superfamily proteins; cl15239
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
FOG: FHA domain [Signal transduction mechanisms]
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
FOG: FHA domain [Signal transduction mechanisms]
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
FOG: FHA domain [Signal transduction mechanisms]
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
Akt pleckstrin homology (PH) domain; cd01241
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, Protein Kinase B; cd05571
Akt pleckstrin homology (PH) domain; cd01241
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, Protein Kinase B; cd05571
Akt pleckstrin homology (PH) domain; cd01241
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, Protein Kinase B; cd05571
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Adenylosuccinate synthetase; smart00788
Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; cd03108
PPPDE putative peptidase domain; pfam05903
Protein of unknown function (DUF3767); pfam12597
SPRY domain; pfam00622
AAA domain; pfam13671
SPRY domain; pfam00622
AAA domain; pfam13671
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Kinesin motor domain. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Kinesins are microtubule-dependent molecular motors that play important roles in intracellular transport and in cell division. In...; cd00106
Kinesin motor, catalytic domain. ATPase; smart00129
MYND finger; pfam01753
SET domain; pfam00856
MYND finger; pfam01753
SET domain; pfam00856
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
Saccharopine dehydrogenase; pfam03435
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Nuclear pore complex assembly; pfam13934
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Vomeronasal organ pheromone receptor family, V1R; cl12106
SCAN oligomerization domain; cd07936
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
Zinc finger, C2H2 type; cl15478
Pyrin death domain found in NALP proteins; cd08320
NACHT domain; pfam05729
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Pyrin death domain found in NALP proteins; cd08320
NACHT domain; pfam05729
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Pyrin death domain found in NALP proteins; cd08320
NACHT domain; pfam05729
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Pyrin death domain found in NALP proteins; cd08320
NACHT domain; pfam05729
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Pyrin death domain found in NALP proteins; cd08320
NACHT domain; pfam05729
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Pyrin death domain found in NALP proteins; cd08320
NACHT domain; pfam05729
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
associated with SPRY domains; smart00589
Domain in SPla and the RYanodine Receptor; smart00449
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
SH3 domain-binding protein 5 (SH3BP5); pfam05276
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Transposase IS4; pfam13843
Transposase IS4; pfam13843
Centrosome-associated C terminus; pfam14160
The SYLF domain (also called DUF500), a novel lipid-binding module, of SH3 domain containing Ysc84-like 1 (SH3YL1) and similar proteins; cd11525
Src homology 3 domain of SH3 domain containing Ysc84-like 1 (SH3YL1) protein; cd11841
The SYLF domain (also called DUF500), a novel lipid-binding module, of SH3 domain containing Ysc84-like 1 (SH3YL1) and similar proteins; cd11525
Src homology 3 domain of SH3 domain containing Ysc84-like 1 (SH3YL1) protein; cd11841
Low molecular weight phosphatase family; cd00115
Low molecular weight phosphotyrosine protein phosphatase; pfam01451
Low molecular weight phosphatase family; cd00115
Low molecular weight phosphotyrosine protein phosphatase; pfam01451
Low molecular weight phosphatase family; cd00115
Low molecular weight phosphotyrosine protein phosphatase; pfam01451
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Syntrophin pleckstrin homology (PH) domain; cd01258
Animal heme peroxidases and related proteins; cl14561
Thyroid peroxidase (TPO); cd09825
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Animal heme peroxidases and related proteins; cl14561
Thyroid peroxidase (TPO); cd09825
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Animal heme peroxidases and related proteins; cl14561
Thyroid peroxidase (TPO); cd09825
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Animal heme peroxidases and related proteins; cl14561
Thyroid peroxidase (TPO); cd09825
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Animal heme peroxidases and related proteins; cl14561
Thyroid peroxidase (TPO); cd09825
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Animal heme peroxidases and related proteins; cl14561
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Leucine rich repeat; pfam13855
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine rich repeat; pfam13855
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine rich repeat C-terminal domain; smart00082
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of peroxidasin; cd05745
Immunoglobulin I-set domain; pfam07679
Fourth immunoglobulin (Ig)-like domain of peroxidasin; cd05746
Animal heme peroxidases and related proteins; cl14561
Animal heme peroxidase domain of peroxidasin and related proteins; cd09826
von Willebrand factor (vWF) type C domain; smart00214
Zinc finger, C2HC type; pfam01530
Zinc finger, C2HC type; pfam01530
Zinc finger, C2HC type; pfam01530
Myelin transcription factor 1; pfam08474
Zinc finger, C2HC type; pfam01530
Zinc finger, C2HC type; pfam01530
Zinc finger, C2HC type; pfam01530
TATA element modulatory factor 1 DNA binding; pfam12329
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
ARD/ARD' family; pfam03079
Cupin domain; pfam07883
Caulimovirus viroplasmin; pfam01693
Eukaryotic RNase H is longer and more complex than their prokaryotic counterparts  and unlike prokaryote, RNase H are essential in higher eukaryote; cd09280
Ribosomal protein S7e; pfam01251
Collagen triple helix repeat (20 copies); pfam01391
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
Collagen triple helix repeat (20 copies); pfam01391
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
Collagen triple helix repeat (20 copies); pfam01391
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
Collagen triple helix repeat (20 copies); pfam01391
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1); cd03591
allantoicase; TIGR02961
Allantoicase repeat; pfam03561
Allantoicase repeat; pfam03561
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
Thymidylate kinase; pfam02223
Thymidylate kinase [Nucleotide transport and metabolism]; COG0125
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
antiviral radical SAM protein viperin; TIGR04278
Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; cd01335
IBR domain; pfam01485
In Between Ring fingers; smart00647
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13857
KAP family P-loop domain; pfam07693
MBOAT, membrane-bound O-acyltransferase family; cl00738
The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 2; cd07642
Centaurin Pleckstrin homology (PH) domain; cd01250
Putative GTPase activating protein for Arf; pfam01412
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 2; cd11966
The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 2; cd07642
Centaurin Pleckstrin homology (PH) domain; cd01250
Putative GTPase activating protein for Arf; pfam01412
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 2; cd11966
Pleckstrin homology-like domain; cl00273
Beta-1 integrin binding protein; pfam10480
Phosphotyrosine-binding domain, phosphotyrosine-interaction (PI) domain; smart00462
Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; COG1236
Metallo-beta-lactamase superfamily; smart00849
Beta-Casp domain; smart01027
RNA-metabolising metallo-beta-lactamase; pfam07521
Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term; pfam11718
Isoamyl-acetate hydrolyzing esterase-like proteins. SGNH_hydrolase subfamily similar to the Saccharomyces cerevisiae IAH1. IAH1 may be the major esterase that hydrolyses isoamyl acetate in sake mash.  The SGNH-family of hydrolases is a diverse family of...; cd01838
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease; TACE_like subfamily. TACE, the tumor-necrosis factor-alpha converting enzyme, releases soluble TNF-alpha from transmembrane pro-TNF-alpha; cd04270
Homologues of snake disintegrins; smart00050
14-3-3 theta/tau (theta in mice, tau in human), an isoform of 14-3-3 protein; cd10023
RNA polymerase I-specific transcription initiation factor Rrn7; pfam11781
CP2 transcription factor; pfam04516
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; cd01049
Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; cd01049
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Ornithine Decarboxylase; cd00622
Diaminopimelate decarboxylase [Amino acid transport and metabolism]; COG0019
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
NUC153 domain; pfam08159
NUC153 domain; pfam08159
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
NUC153 domain; pfam08159
V-ATPase subunit C; pfam03223
V-ATPase subunit C; pfam03223
PDIa family, P5 subfamily; composed of eukaryotic proteins similar to human P5, a PDI-related protein with a domain structure of aa'b (where a and a' are redox active TRX domains and b is a redox inactive TRX-like domain). Like PDI, P5 is located in the...; cd03001
PDIa family, P5 subfamily; composed of eukaryotic proteins similar to human P5, a PDI-related protein with a domain structure of aa'b (where a and a' are redox active TRX domains and b is a redox inactive TRX-like domain). Like PDI, P5 is located in the...; cd03001
P5 family, C-terminal redox inactive TRX-like domain; P5 is a protein disulfide isomerase (PDI)-related protein with a domain structure of aa'b (where a and a' are redox active TRX domains and b is a redox inactive TRX-like domain). Like PDI, P5 is...; cd02983
BTB/POZ domain; cl02518
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion channel; pfam07885
Catalytic domain of the Protein Serine/Threonine Kinase, Rho-associated coiled-coil containing protein kinase; cd05596
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Rho-associated coiled-coil containing protein kinase 2; cd11638
Rho Binding; pfam08912
Pleckstrin homology-like domain; cl00273
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Pleckstrin homology-like domain; cl00273
E2F/DP family winged-helix DNA-binding domain; pfam02319
7 transmembrane receptor (rhodopsin family); pfam00001
lipin, N-terminal conserved region; pfam04571
LNS2 (Lipin/Ned1/Smp2); pfam08235
This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain and phosphatidylinositol transfer proteins; smart00775
lipin, N-terminal conserved region; pfam04571
LNS2 (Lipin/Ned1/Smp2); pfam08235
This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain and phosphatidylinositol transfer proteins; smart00775
lipin, N-terminal conserved region; pfam04571
lipin, N-terminal conserved region; pfam04571
LNS2 (Lipin/Ned1/Smp2); pfam08235
This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain and phosphatidylinositol transfer proteins; smart00775
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Lecithin retinol acyltransferase; pfam04970
Secretory pathway protein Sec39; pfam08314
Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; COG0513
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Domain in SPla and the RYanodine Receptor; smart00449
Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; COG0513
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Myc amino-terminal region; pfam01056
Myc amino-terminal region; pfam01056
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Protein of unknown function (DUF1394); pfam07159
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Eukaryotic SMC6 proteins; SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains.  Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal...; cd03276
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Eukaryotic SMC6 proteins; SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains.  Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal...; cd03276
PIN domain of Gap Endonuclease 1, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs; cd09869
H3TH domain of Gap Endonuclease 1, a structure-specific, divalent-metal-ion dependent, 5' nuclease; cd09905
PIN (PilT N terminus) domain: Superfamily; cl14812
PIN domain of Gap Endonuclease 1, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs; cd09869
H3TH domain of Gap Endonuclease 1, a structure-specific, divalent-metal-ion dependent, 5' nuclease; cd09905
PIN (PilT N terminus) domain: Superfamily; cl14812
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
5'-nucleotidase; pfam06189
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
short chain dehydrogenase; Provisional
retinol dehydrogenases (retinol-DHs), classical (c) SDRs; cd09807
5'-nucleotidase; pfam06189
5'-nucleotidase; pfam06189
5'-nucleotidase; pfam06189
5'-nucleotidase; pfam06189
5'-nucleotidase; pfam06189
5'-nucleotidase; pfam06189
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Region in Clathrin and VPS; pfam00637
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Region in Clathrin and VPS; pfam00637
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Complement Clr-like EGF-like; pfam12662
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Trimeric coiled-coil oligomerisation domain of matrilin; pfam10393
Golgi 4-transmembrane spanning transporter; TIGR00799
Syndecan domain; pfam01034
putative band 4.1 homologues' binding motif; smart00294
Syndecan domain; pfam01034
putative band 4.1 homologues' binding motif; smart00294
Pumilio-family RNA binding domain; cd07920
RNA-binding protein of the Puf family, translational repressor [Translation, ribosomal structure and biogenesis]
GTPase SAR1 and related small G proteins [General function prediction only]
Ras homology family A (RhoA)-like includes RhoA, RhoB and RhoC; cd01870
The phosphoinositide binding Phox Homology domain of HS1BP3; cd06868
TGF-beta propeptide; pfam00688
Transforming growth factor-beta (TGF-beta) family; smart00204
Uncharacterized conserved protein (DUF2305); pfam10230
Alpha/beta hydrolase family; pfam12697
Lipoprotein amino terminal region; pfam01347
Domain of unknown function (DUF1943); pfam09172
Domain of Unknown Function (DUF1081); pfam06448
ATPase involved in DNA repair [DNA replication, recombination, and repair]; COG0419
apoB-48, residue Gln(2180) is modified by RNA editing from CAA to a stop codon UAA.
Apolipoprotein B100 C terminal; pfam12491
kelch-like protein; Provisional
BTB/POZ domain; pfam00651
BTB And C-terminal Kelch; pfam07707
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch motif; pfam01344
Kelch motif; pfam13964
Kelch motif; pfam01344
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
Bromodomain; sub-family co-occurring with AAA domains. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine. The structure(2DKW) in this...; cd05528
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
Bromodomain; sub-family co-occurring with AAA domains. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine. The structure(2DKW) in this...; cd05528
SEP domain; pfam08059
p47-like ubiquitin domain; cd01770
melibiose:sodium symporter; Provisional; cl15392
MFS/sugar transport protein; pfam13347
FKBP-type peptidyl-prolyl cis-trans isomerase; pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase; pfam00254
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
alcohol dehydrogenase; Provisional
PIG3 p53-inducible quinone oxidoreductase; cd05276
alcohol dehydrogenase; Provisional
PIG3 p53-inducible quinone oxidoreductase; cd05276
PIG3 p53-inducible quinone oxidoreductase; cd05276
Profilin binds actin monomers, membrane polyphosphoinositides such as PI(4,5)P2, and poly-L-proline. Profilin can inhibit actin polymerization into F-actin by binding to monomeric actin (G-actin) and terminal F-actin subunits, but - as a regulator of the...; cd00148
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
First Src homology 3 domain (or SH3A) of Intersectin-2; cd11988
Second Src homology 3 domain (or SH3B) of Intersectin-2; cd11990
Third Src homology 3 domain (or SH3C) of Intersectin-2; cd11992
Fourth Src homology 3 domain (or SH3D) of Intersectin-2; cd11994
Fifth Src homology 3 domain (or SH3E) of Intersectin-2; cd11996
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology (PH) domain; cd00821
C2 domain present in Intersectin; cd08375
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
First Src homology 3 domain (or SH3A) of Intersectin-2; cd11988
Second Src homology 3 domain (or SH3B) of Intersectin-2; cd11990
Third Src homology 3 domain (or SH3C) of Intersectin-2; cd11992
Fourth Src homology 3 domain (or SH3D) of Intersectin-2; cd11994
Fifth Src homology 3 domain (or SH3E) of Intersectin-2; cd11996
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology (PH) domain; cd00821
C2 domain present in Intersectin; cd08375
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
First Src homology 3 domain (or SH3A) of Intersectin-2; cd11988
Second Src homology 3 domain (or SH3B) of Intersectin-2; cd11990
Third Src homology 3 domain (or SH3C) of Intersectin-2; cd11992
Fourth Src homology 3 domain (or SH3D) of Intersectin-2; cd11994
Fifth Src homology 3 domain (or SH3E) of Intersectin-2; cd11996
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
Steroid receptor coactivator; pfam08832
Nuclear receptor coactivator; pfam08815
Domain of unknown function (DUF1518); pfam07469
Domain of unknown function (DUF1518); pfam07469
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
Steroid receptor coactivator; pfam08832
Nuclear receptor coactivator; pfam08815
Domain of unknown function (DUF1518); pfam07469
Domain of unknown function (DUF1518); pfam07469
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS fold; pfam00989
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
Steroid receptor coactivator; pfam08832
Nuclear receptor coactivator; pfam08815
Domain of unknown function (DUF1518); pfam07469
Domain of unknown function (DUF1518); pfam07469
Peptidyl-tRNA hydrolase, type 2 (PTH2)_like . Peptidyl-tRNA hydrolase activity releases tRNA from the premature translation termination product peptidyl-tRNA. Two structurally different enzymes have been reported  to encode such activity, Pth present in...; cd02429
Cenp-O kinetochore centromere component; pfam09496
Cenp-O kinetochore centromere component; pfam09496
Adenylyl- / guanylyl cyclase, catalytic domain; smart00044
cyclase homology domain; cd07302
Adenylyl- / guanylyl cyclase, catalytic domain; smart00044
cyclase homology domain; cd07302
Rab GTPase family J-like (RabJ-like); cd04119
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
Rab GTPase family J-like (RabJ-like); cd04119
Pro-opiomelanocortin, N-terminal region; pfam08384
Corticotropin ACTH domain; pfam00976
Opioids neuropeptide; pfam08035
Pro-opiomelanocortin, N-terminal region; pfam08384
Corticotropin ACTH domain; pfam00976
Opioids neuropeptide; pfam08035
The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis.  In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in...; cd05835
ADDz domain of DNA (cytosine-5) methyltransferases (C5-MTases) 3 a (Dnmt3a); cd11729
Site-specific DNA methylase [DNA replication, recombination, and repair]; COG0270
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis.  In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in...; cd05835
ADDz domain of DNA (cytosine-5) methyltransferases (C5-MTases) 3 a (Dnmt3a); cd11729
Site-specific DNA methylase [DNA replication, recombination, and repair]; COG0270
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis.  In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in...; cd05835
ADDz domain of DNA (cytosine-5) methyltransferases (C5-MTases) 3 a (Dnmt3a); cd11729
Site-specific DNA methylase [DNA replication, recombination, and repair]; COG0270
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Seryl-tRNA synthetase N-terminal domain; pfam02403
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Flagellar protein FliT; pfam05400
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Seryl-tRNA synthetase N-terminal domain; pfam02403
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Seryl-tRNA synthetase N-terminal domain; pfam02403
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Flagellar protein FliT; pfam05400
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Flagellar protein FliT; pfam05400
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Flagellar protein FliT; pfam05400
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Seryl-tRNA synthetase N-terminal domain; pfam02403
Transcriptional enhancer, Asx-hm domain; pfam13919
PHD domain of transcriptional enhancer, Asx; pfam13922
Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; cl00286
Kinesin motor, catalytic domain. ATPase; smart00129
Rab GTPase families 8, 10, 13 (Rab8, Rab10, Rab13); cd01867
Cell-cycle sustaining, positive selection; pfam12736
SAM domain of GAREM subfamily; cd09525
Cell-cycle sustaining, positive selection; pfam12736
SAM domain of GAREM subfamily; cd09525
fatty acid oxidation complex, alpha subunit, mitochondrial; TIGR02441
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; cd06558
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; pfam02737
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; pfam00725
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; cd00751
acetyl-CoA acetyltransferases; TIGR01930
Hormone receptor domain; cl02422
Domain of unknown function (DUF3497); pfam12003
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
Hormone receptor domain; cl02422
Domain of unknown function (DUF3497); pfam12003
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
Hormone receptor domain; cl02422
Domain of unknown function (DUF3497); pfam12003
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); cl12142
CDP-alcohol phosphatidyltransferase; cl00453
MutS2 family protein; TIGR01069
FerB (NUC096) domain; pfam08150
C2 domain fourth repeat in Ferlin; cd04017
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
C2 domain first repeat in Ferlin; cd08373
C2 domain second repeat in Ferlin; cd04011
FerI (NUC094) domain; pfam08151
C2 domain third repeat in Ferlin; cd04018
FerB (NUC096) domain; pfam08150
C2 domain fourth repeat in Ferlin; cd04017
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
FerB (NUC096) domain; pfam08150
C2 domain fourth repeat in Ferlin; cd04017
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
FerB (NUC096) domain; pfam08150
C2 domain fourth repeat in Ferlin; cd04017
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
Protein of unknown function (DUF2475); pfam10629
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ion channel; pfam07885
Ion channel; pfam07885
EamA-like transporter family; pfam00892
Histone H3; smart00428
Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding...; cl00074
phenylhydantoinase; Validated
D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; cd01314
phenylhydantoinase; Validated
D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; cd01314
phenylhydantoinase; Validated
D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; cd01314
Calponin homology (CH) domain; pfam00307
EB1-like C-terminal motif; pfam03271
Uncharacterized conserved protein (DUF2359); pfam10151
Uncharacterized conserved protein (DUF2359); pfam10151
Peptidase M14-like domain of ATP/GTP binding protein (AGBL)-5 and related proteins; cd06236
M14 family of metallocarboxypeptidases and related proteins; cl11393
Peptidase M14-like domain of ATP/GTP binding protein (AGBL)-5 and related proteins; cd06236
M14 family of metallocarboxypeptidases and related proteins; cl11393
Oligosaccaryltransferase; pfam10215
EMI domain; pfam07546
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cl00147
Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to fructose-1-phosphate (F1P), the first step in the metabolism of dietary fructose.  KHK can also phosphorylate several other furanose sugars.  It is found in higher eukaryotes...; cd01939
Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; COG0524
Ketohexokinase (fructokinase, KHK) catalyzes the phosphorylation of fructose to fructose-1-phosphate (F1P), the first step in the metabolism of dietary fructose.  KHK can also phosphorylate several other furanose sugars.  It is found in higher eukaryotes...; cd01939
Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; COG0524
EF-hand domain pair; pfam13499
EF-hand domain pair; pfam13499
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
helix loop helix domain; smart00353
Na(+)/multivitamin cotransporter SMVT and related proteins; solute-binding domain; cd11504
carbamoyl phosphate synthase small subunit; Reviewed
Carbamoyl-phosphate synthase small chain, CPSase domain; smart01097
Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; cd01744
carbamoyl-phosphate synthase, large subunit; TIGR01369
Carbamoyl-phosphate synthase L chain, N-terminal domain; pfam00289
ATP-grasp domain; cl03087
Carbamoyl-phosphate synthetase large chain, oligomerisation domain; pfam02787
Carbamoyl-phosphate synthase L chain, N-terminal domain; pfam00289
ATP-grasp domain; cl03087
Methylglyoxal synthase-like domain found in pyr1 and URA1-like carbamoyl phosphate synthetases (CPS), including ammonia-dependent CPS Type I, and glutamine-dependent CPS Type III. These are multidomain proteins, in which MGS is the C-terminal domain; cd01423
Dihydroorotase and related cyclic amidohydrolases [Nucleotide transport and metabolism]; COG0044
The eukaryotic CAD protein is a trifunctional enzyme of carbamoylphosphate synthetase-aspartate transcarbamoylase-dihydroorotase, which catalyzes the first three steps of de novo pyrimidine nucleotide biosynthesis. Dihydroorotase (DHOase) catalyzes the...; cd01316
aspartate carbamoyltransferase catalytic subunit; Provisional; PRK00856
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; pfam02729
Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; pfam00185
cation diffusion facilitator family transporter; TIGR01297
Cation efflux family; pfam01545
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Mpv17 / PMP22 family; pfam04117
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Initiation factor 2 subunit family; pfam01008
Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]; cl00348
Initiation factor 2 subunit family; pfam01008
Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]; cl00348
Initiation factor 2 subunit family; pfam01008
Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]; cl00348
The phosphoinositide binding Phox Homology domain of Sorting Nexins 17 and 31; cd06885
Ubiquitin-like proteins; cl00155
The phosphoinositide binding Phox Homology domain of Sorting Nexins 17 and 31; cd06885
Ubiquitin-like proteins; cl00155
The phosphoinositide binding Phox Homology domain of Sorting Nexins 17 and 31; cd06885
Ubiquitin-like proteins; cl00155
The phosphoinositide binding Phox Homology domain of Sorting Nexins 17 and 31; cd06885
Ubiquitin-like proteins; cl00155
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Serine/threonine phosphatases, family 2C, catalytic domain; smart00332
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; cd00143
Protein phosphatase 2C; pfam00481
Catalytic domain of Protein Kinases; cd00180
Serine/Threonine protein kinases, catalytic domain; smart00220
Beta-casein like protein; pfam12304
Beta-casein like protein; pfam12304
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; cl00389
SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; cl00389
SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; cl00389
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]; COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]; COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]; COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]; COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]; COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]; COG5189
chromosome segregation protein; Provisional
Conserved hypothetical ATP binding protein; pfam03029
Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); cd00882
Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); cd00882
Conserved hypothetical ATP binding protein; pfam03029
Conserved hypothetical ATP binding protein; pfam03029
Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); cd00882
Conserved hypothetical ATP binding protein; pfam03029
Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); cd00882
Bromodomain transcription factors and PHD domain containing proteins; smart00576
FOG: FHA domain [Signal transduction mechanisms]
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
Double-stranded RNA binding motif; pfam00035
50S ribosomal protein L33; Validated; PRK00595
Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; COG0524
Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; cd01174
Brain and reproductive organ-expressed protein (BRE); pfam06113
Brain and reproductive organ-expressed protein (BRE); pfam06113
Brain and reproductive organ-expressed protein (BRE); pfam06113
Brain and reproductive organ-expressed protein (BRE); pfam06113
Brain and reproductive organ-expressed protein (BRE); pfam06113
Brain and reproductive organ-expressed protein (BRE); pfam06113
Brain and reproductive organ-expressed protein (BRE); pfam06113
Brain and reproductive organ-expressed protein (BRE); pfam06113
Brain and reproductive organ-expressed protein (BRE); pfam06113
Brain and reproductive organ-expressed protein (BRE); pfam06113
Brain and reproductive organ-expressed protein (BRE); pfam06113
Brain and reproductive organ-expressed protein (BRE); pfam06113
Phospholipase-B_like. This subgroup of the SGNH-family of lipolytic enzymes may have both esterase and phospholipase-A/lysophospholipase activity.  It's members may be involved in the conversion of phosphatidylcholine to fatty acids and...; cd01824
Phospholipase-B_like. This subgroup of the SGNH-family of lipolytic enzymes may have both esterase and phospholipase-A/lysophospholipase activity.  It's members may be involved in the conversion of phosphatidylcholine to fatty acids and...; cd01824
Phospholipase-B_like. This subgroup of the SGNH-family of lipolytic enzymes may have both esterase and phospholipase-A/lysophospholipase activity.  It's members may be involved in the conversion of phosphatidylcholine to fatty acids and...; cd01824
Phospholipase-B_like. This subgroup of the SGNH-family of lipolytic enzymes may have both esterase and phospholipase-A/lysophospholipase activity.  It's members may be involved in the conversion of phosphatidylcholine to fatty acids and...; cd01824
Phospholipase-B_like. This subgroup of the SGNH-family of lipolytic enzymes may have both esterase and phospholipase-A/lysophospholipase activity.  It's members may be involved in the conversion of phosphatidylcholine to fatty acids and...; cd01824
Phospholipase-B_like. This subgroup of the SGNH-family of lipolytic enzymes may have both esterase and phospholipase-A/lysophospholipase activity.  It's members may be involved in the conversion of phosphatidylcholine to fatty acids and...; cd01824
Phospholipase-B_like. This subgroup of the SGNH-family of lipolytic enzymes may have both esterase and phospholipase-A/lysophospholipase activity.  It's members may be involved in the conversion of phosphatidylcholine to fatty acids and...; cd01824
Phospholipase-B_like. This subgroup of the SGNH-family of lipolytic enzymes may have both esterase and phospholipase-A/lysophospholipase activity.  It's members may be involved in the conversion of phosphatidylcholine to fatty acids and...; cd01824
serine/threonine-protein phosphatase; Provisional
PP1, PPKL (PP1 and kelch-like) enzymes,  and related proteins, metallophosphatase domain; cd07414
serine/threonine-protein phosphatase; Provisional
PP1, PPKL (PP1 and kelch-like) enzymes,  and related proteins, metallophosphatase domain; cd07414
Cell cycle regulatory protein; pfam11357
Cell cycle regulatory protein; pfam11357
Cell cycle regulatory protein; pfam11357
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Dip2/Utp12 Family; pfam04003
CLASP N terminal; pfam12348
transcriptional regulator ICP4; Provisional
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
CAP-Gly domain; pfam01302
CAP-Gly domain; pfam01302
CAP-Gly domain; pfam01302
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Catalytic domain of the Protein Tyrosine Kinases, Anaplastic Lymphoma Kinase and Leukocyte Tyrosine Kinase; cd05036
Protein tyrosine kinase; pfam07714
Yippee putative zinc-binding protein; pfam03226
Yippee putative zinc-binding protein; pfam03226
Yippee putative zinc-binding protein; pfam03226
Yippee putative zinc-binding protein; pfam03226
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; cd07990
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; cd07990
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction; cd00044
Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are...; cl00165
EF-hand domain pair; pfam13833
Predicted glycosyltransferases [General function prediction only]
pp-GalNAc-T initiates the formation of mucin-type O-linked glycans; cd02510
Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; cd00161
Ricin-type beta-trefoil lectin domain; pfam00652
Predicted glycosyltransferases [General function prediction only]
pp-GalNAc-T initiates the formation of mucin-type O-linked glycans; cd02510
Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; cd00161
Ricin-type beta-trefoil lectin domain; pfam00652
Predicted glycosyltransferases [General function prediction only]
pp-GalNAc-T initiates the formation of mucin-type O-linked glycans; cd02510
Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; cd00161
Ricin-type beta-trefoil lectin domain; pfam00652
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction; cd00044
Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are...; cd00214
Eps15 homology domain (EHD), C-terminal domain; cd09913
Dynamin family; pfam00350
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
xanthine dehydrogenase
[2Fe-2S] binding domain; pfam01799
CO dehydrogenase flavoprotein C-terminal domain; pfam03450
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; pfam01315
Molybdopterin-binding domain of aldehyde dehydrogenase; pfam02738
3-oxo-5-alpha-steroid 4-dehydrogenase; pfam02544
Memo (mediator of ErbB2-driven cell motility) is co-precipitated with the C terminus of ErbB2, a protein involved in cell motility; cd07361
Memo (mediator of ErbB2-driven cell motility) is co-precipitated with the C terminus of ErbB2, a protein involved in cell motility; cd07361
Dpy-30 motif; pfam05186
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This MIT domain sub-family is found in the AAA protein spastin, a probable ATPase involved in the assembly or function of nuclear protein complexes; spastins might also be...; cd02679
Microtubule Interacting and Trafficking molecule domain; smart00745
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This MIT domain sub-family is found in the AAA protein spastin, a probable ATPase involved in the assembly or function of nuclear protein complexes; spastins might also be...; cd02679
Microtubule Interacting and Trafficking molecule domain; smart00745
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
Cation efflux family; pfam01545
Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; COG1230
Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; COG1230
Cation efflux family; pfam01545
Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; COG1230
Cation efflux family; pfam01545
Cation efflux family; pfam01545
Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; COG1230
Caspase activation and recruitment domain found in Caspase-1 and related proteins; cd08325
NACHT domain; pfam05729
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Caspase activation and recruitment domain found in Caspase-1 and related proteins; cd08325
NACHT domain; pfam05729
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Caspase activation and recruitment domain found in Caspase-1 and related proteins; cd08325
NACHT domain; pfam05729
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Yip1 domain; cl12048
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Protein of unknown function (DUF3643); pfam12356
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Complement Clr-like EGF-like; pfam12662
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
TB domain; pfam00683
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Complement Clr-like EGF-like; pfam12662
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
TB domain; pfam00683
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain; smart00179
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
TB domain; pfam00683
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain; smart00179
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Complement Clr-like EGF-like; pfam12662
TB domain; pfam00683
TB domain; pfam00683
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain; smart00179
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
TB domain; pfam00683
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain; smart00179
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein of unknown function (DUF2465); pfam10239
Insulin-like growth factor binding protein; cl02472
von Willebrand factor type C domain; cl02515
von Willebrand factor (vWF) type C domain; smart00214
Antistasin family; pfam02822
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
von Willebrand factor type C domain; cl02515
FEZ-like protein; pfam07763
FEZ-like protein; pfam07763
LCCL domain; pfam03815
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
von Willebrand factor (vWF) type A domain; equivalent to the I-domain of integrins.  This domain has a variety of functions including: intermolecular adhesion, cell migration, signalling, transcription, and DNA repair. In integrins these domains form...; cd01472
LCCL domain; pfam03815
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
von Willebrand factor (vWF) type A domain; equivalent to the I-domain of integrins.  This domain has a variety of functions including: intermolecular adhesion, cell migration, signalling, transcription, and DNA repair. In integrins these domains form...; cd01472
LCCL domain; pfam03815
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
von Willebrand factor (vWF) type A domain; equivalent to the I-domain of integrins.  This domain has a variety of functions including: intermolecular adhesion, cell migration, signalling, transcription, and DNA repair. In integrins these domains form...; cd01472
LCCL domain; pfam03815
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
von Willebrand factor (vWF) type A domain; equivalent to the I-domain of integrins.  This domain has a variety of functions including: intermolecular adhesion, cell migration, signalling, transcription, and DNA repair. In integrins these domains form...; cd01472
LCCL domain; pfam03815
Striatin family; pfam08232
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
G-patch domain; pfam01585
Domain of unknown function (DUF4187); pfam13821
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif; smart00358
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif; smart00358
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif; smart00358
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Sulfotransferase family; cl14559
Sulfotransferase domain; pfam00685
CBF/Mak21 family; cl10505
Uncharacterized conserved protein [Function unknown]
Putative S-adenosyl-L-methionine-dependent methyltransferase; pfam02636
Uncharacterized conserved protein [Function unknown]
Putative S-adenosyl-L-methionine-dependent methyltransferase; pfam02636
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain; cd01239
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
M28 Zn-Peptidase Glutaminyl Cyclase; cd03880
P21-Rho-binding domain; smart00285
P21-Rho-binding domain; smart00285
P21-Rho-binding domain; smart00285
P21-Rho-binding domain; smart00285
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Guanylate-binding protein (GBP) family (N-terminal domain); cd01851
Guanylate-binding protein (GBP) family (N-terminal domain); cd01851
hnRNP-L/PTB/hephaestus splicing factor family; TIGR01649
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
hnRNP-L/PTB/hephaestus splicing factor family; TIGR01649
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Galactose mutarotase and related enzymes [Carbohydrate transport and metabolism]; COG2017
galactose mutarotase_like; cd09019
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zinc knuckle; cl15298
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zinc knuckle; cl15298
Gemin6 protein; pfam06372
Gemin 6; cd11676
zinc finger; smart00356
DEAD-like helicases superfamily; smart00487
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
HrpA-like helicases [DNA replication, recombination, and repair]; COG1643
Helicase associated domain (HA2); pfam04408
Oligonucleotide/oligosaccharide-binding (OB)-fold; pfam07717
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases; smart00698
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Core histone H2A/H2B/H3/H4; pfam00125
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Son of Sevenless (SOS) Pleckstrin homology (PH) domain; cd01261
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase Like 1 and 4; cd07847
Protein kinase domain; pfam00069
Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase-like Protein Serine/Threonine Kinases; cd06613
Serine/Threonine protein kinases, catalytic domain; smart00220
Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2; smart00036
Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase-like Protein Serine/Threonine Kinases; cd06613
Serine/Threonine protein kinases, catalytic domain; smart00220
Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2; smart00036
PMP-22/EMP/MP20/Claudin tight junction; pfam13903
PMP-22/EMP/MP20/Claudin family; cl15797
THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; cd11715
THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; cd11715
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
sodium/calcium exchanger 1; TIGR00845
Sodium/calcium exchanger protein; pfam01699
Calx-beta domain; pfam03160
Domains in Na-Ca exchangers and integrin-beta4; smart00237
Sodium/calcium exchanger protein; pfam01699
sodium/calcium exchanger 1; TIGR00845
Sodium/calcium exchanger protein; pfam01699
Calx-beta domain; pfam03160
Domains in Na-Ca exchangers and integrin-beta4; smart00237
Sodium/calcium exchanger protein; pfam01699
sodium/calcium exchanger 1; TIGR00845
Sodium/calcium exchanger protein; pfam01699
Calx-beta domain; pfam03160
Domains in Na-Ca exchangers and integrin-beta4; smart00237
Sodium/calcium exchanger protein; pfam01699
sodium/calcium exchanger 1; TIGR00845
Sodium/calcium exchanger protein; pfam01699
Calx-beta domain; pfam03160
Domains in Na-Ca exchangers and integrin-beta4; smart00237
Sodium/calcium exchanger protein; pfam01699
sodium/calcium exchanger 1; TIGR00845
Sodium/calcium exchanger protein; pfam01699
Calx-beta domain; pfam03160
Domains in Na-Ca exchangers and integrin-beta4; smart00237
Sodium/calcium exchanger protein; pfam01699
Protein Kinases, catalytic domain; cl09925
HELP motif; pfam03451
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
HELP motif; pfam03451
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Cytochrome c oxidase subunit VIIa. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; cd00928
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH...; cd04709
ELM2 domain; pfam01448
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cl15779
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C; cd00202
G protein-coupled chemokine receptor-like protein; Provisional
3-hydroxyanthranilic acid dioxygenase; pfam06052
Tis11B like protein, N terminus; pfam04553
Zinc finger C-x8-C-x5-C-x3-H type (and similar); pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar); pfam00642
Putative death-receptor fusion protein (DUF2428); pfam10350
Putative death-receptor fusion protein (DUF2428); pfam10350
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology (PH) domain; cd00821
Domain in Myosin and Kinesin Tails; smart00139
Band 4.1 homologues; smart00295
FERM central domain; pfam00373
Dynein light intermediate chain (DLIC); pfam05783
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Dynein light intermediate chain (DLIC); pfam05783
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Dynein light intermediate chain (DLIC); pfam05783
The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors.  The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red...; cd03234
The Eye Pigment Precursor Transporter (EPP) Family protein; TIGR00955
ABC-2 type transporter; pfam01061
The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors.  The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red...; cd03234
The Eye Pigment Precursor Transporter (EPP) Family protein; TIGR00955
ABC-2 type transporter; pfam01061
PPR repeat family; pfam13041
PPR repeat family; pfam13041
PPR repeat family; pfam13041
Protein phosphatase 2C; pfam00481
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; cd00143
Protein serine/threonine phosphatase 2C, C-terminal domain; pfam07830
Protein phosphatase 2C; pfam00481
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; cd00143
Protein serine/threonine phosphatase 2C, C-terminal domain; pfam07830
Protein phosphatase 2C; pfam00481
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; cd00143
Protein serine/threonine phosphatase 2C, C-terminal domain; pfam07830
Protein phosphatase 2C; pfam00481
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; cd00143
Protein serine/threonine phosphatase 2C, C-terminal domain; pfam07830
Protein serine/threonine phosphatase 2C, C-terminal domain; pfam07830
Alpha amylase catalytic domain found in Solute Carrier family 3 member 1 proteins; cd11359
alpha,alpha-phosphotrehalase; TIGR02403
Prolyl oligopeptidase family; pfam00326
Prolyl oligopeptidase family; pfam00326
Protease II [Amino acid transport and metabolism]; COG1770
Prolyl oligopeptidase family; pfam00326
Protease II [Amino acid transport and metabolism]; COG1770
Prolyl oligopeptidase family; pfam00326
Protease II [Amino acid transport and metabolism]; COG1770
Prolyl oligopeptidase family; pfam00326
Protease II [Amino acid transport and metabolism]; COG1770
Prolyl oligopeptidase family; pfam00326
Protease II [Amino acid transport and metabolism]; COG1770
Prolyl oligopeptidase family; pfam00326
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Transcriptional accessory protein [Transcription]; COG2183
Tex-like protein N-terminal domain; pfam09371
Likely ribonuclease with RNase H fold; smart00732
S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; cd05685
C2 domain in Protein Kinase C (PKC) epsilon; cd04014
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, Novel Protein Kinase C epsilon; cd05591
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Hypoxia-inducible factor-1; pfam11413
HIF-1 alpha C terminal transactivation domain; pfam08778
ATP synthase (E/31 kDa) subunit; pfam01991
ATP synthase B/B' CF(0); cl07975
GTPase SAR1 and related small G proteins [General function prediction only]
Rho GTPase TC10 (Tc10); cd04135
GPI biosynthesis protein family Pig-F; pfam06699
GPI biosynthesis protein family Pig-F; pfam06699
Microtubule-associated protein CRIPT; pfam10235
Suppressor of cytokine signalling; pfam12610
Src homology 2 (SH2) domain; cl15255
SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting...; cd03739
Suppressor of cytokine signalling; pfam12610
Src homology 2 (SH2) domain; cl15255
SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting...; cd03739
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cl08302
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cl08302
EF-hand domain pair; pfam13499
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13432
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13432
TPR repeat; pfam13414
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases; cd00191
MutS domain I; pfam01624
Mismatch repair ATPase (MutS family) [DNA replication, recombination, and repair]; COG0249
MutS domain II; pfam05188
MutS family domain IV; pfam05190
MutS2 homolog in eukaryotes.  The MutS protein initiates DNA mismatch repair by recognizing mispaired and unpaired bases embedded in duplex DNA and activating endo- and exonucleases to remove the mismatch.  Members of the MutS family possess C-terminal...; cd03285
MutS domain I; pfam01624
MutS domain II; pfam05188
DNA-binding domain of DNA mismatch repair MUTS family; smart00533
MutS family domain IV; pfam05190
MutS2 homolog in eukaryotes.  The MutS protein initiates DNA mismatch repair by recognizing mispaired and unpaired bases embedded in duplex DNA and activating endo- and exonucleases to remove the mismatch.  Members of the MutS family possess C-terminal...; cd03285
Ion channel; pfam07885
Ion channel; pfam07885
The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS.   The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been...; cd05837
Mismatch repair ATPase (MutS family) [DNA replication, recombination, and repair]; COG0249
MutS domain I; pfam01624
MutS domain II; pfam05188
MutS family domain IV; pfam05190
MutS domain V; pfam00488
F-box-like; pfam12937
Right handed beta helix region; pfam13229
Right handed beta helix region; pfam13229
parallel beta-helix repeat (two copies); TIGR03804
Right handed beta helix region; pfam13229
Putative zinc finger in N-recognin (UBR box); pfam02207
F-box-like; pfam12937
Right handed beta helix region; pfam13229
Right handed beta helix region; pfam13229
parallel beta-helix repeat (two copies); TIGR03804
Right handed beta helix region; pfam13229
Putative zinc finger in N-recognin (UBR box); pfam02207
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
Predicted coiled-coil domain-containing protein; pfam10205
Predicted coiled-coil domain-containing protein; pfam10212
Predicted coiled-coil domain-containing protein; pfam10205
Predicted coiled-coil domain-containing protein; pfam10212
Predicted coiled-coil domain-containing protein; pfam10205
Predicted coiled-coil domain-containing protein; pfam10212
Adaptor complexes medium subunit family; pfam00928
Mu homology domain (MHD) of adaptor-like protein (AP-like), stonin-1 (also called Stoned B-like factor); cd09262
Precursor of TFIIA alpha and beta subunits and similar proteins; cd07976
Transcription factor IIA, alpha/beta subunit; pfam03153
Adaptor complexes medium subunit family; pfam00928
Mu homology domain (MHD) of adaptor-like protein (AP-like), stonin-1 (also called Stoned B-like factor); cd09262
Precursor of TFIIA alpha and beta subunits and similar proteins; cd07976
Transcription factor IIA, alpha/beta subunit; pfam03153
Precursor of TFIIA alpha and beta subunits and similar proteins; cd07976
Adaptor complexes medium subunit family; pfam00928
Mu homology domain (MHD) of adaptor-like protein (AP-like), stonin-1 (also called Stoned B-like factor); cd09262
Precursor of TFIIA alpha and beta subunits and similar proteins; cd07976
Transcription factor IIA, alpha/beta subunit; pfam03153
Precursor of TFIIA alpha and beta subunits and similar proteins; cd07976
Adaptor complexes medium subunit family; pfam00928
Mu homology domain (MHD) of adaptor-like protein (AP-like), stonin-1 (also called Stoned B-like factor); cd09262
Adaptor complexes medium subunit family; pfam00928
Mu homology domain (MHD) of adaptor-like protein (AP-like), stonin-1 (also called Stoned B-like factor); cd09262
Precursor of TFIIA alpha and beta subunits and similar proteins; cd07976
Transcription factor IIA, alpha/beta subunit; pfam03153
Precursor of TFIIA alpha and beta subunits and similar proteins; cd07976
Transcription factor IIA, alpha/beta subunit; pfam03153
Precursor of TFIIA alpha and beta subunits and similar proteins; cd07976
Leucine rich repeats (6 copies); pfam13306
7 transmembrane receptor (rhodopsin family); pfam00001
Leucine rich repeat N-terminal domain; pfam01462
Leucine rich repeat; pfam13855
Leucine Rich repeats (2 copies); pfam12799
Gonadotropin hormone receptor transmembrane region; pfam12369
7 transmembrane receptor (rhodopsin family); pfam00001
Leucine rich repeat N-terminal domain; pfam01462
Leucine rich repeat; pfam13855
Gonadotropin hormone receptor transmembrane region; pfam12369
7 transmembrane receptor (rhodopsin family); pfam00001
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
putative band 4.1 homologues' binding motif; smart00294
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
putative band 4.1 homologues' binding motif; smart00294
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
putative band 4.1 homologues' binding motif; smart00294
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha...; cd03722
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha...; cd03722
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha...; cd03722
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha...; cd03722
GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; cd06661
Glucosidase II beta subunit-like protein; pfam07915
Glucosidase II beta subunit-like protein; cl06793
Glucosidase II beta subunit-like protein; pfam07915
Glucosidase II beta subunit-like protein; pfam07915
Glucosidase II beta subunit-like protein; cl06793
Glucosidase II beta subunit-like protein; pfam07915
Glucosidase II beta subunit-like protein; pfam07915
Glucosidase II beta subunit-like protein; cl06793
Glucosidase II beta subunit-like protein; pfam07915
7 transmembrane receptor (rhodopsin family); pfam00001
Domain of unknown function (DUF3437); pfam11919
Acylphosphatase; pfam00708
Nucleosome assembly protein (NAP); pfam00956
(NAP-L) nucleosome assembly protein -L; Provisional; cl08298
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Spectrin repeat; pfam00435
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeat; pfam00435
Beta-spectrin pleckstrin homology (PH) domain; cd01253
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Spectrin repeat; pfam00435
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeat; pfam00435
HELP motif; pfam03451
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
HELP motif; pfam03451
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
HELP motif; pfam03451
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Reticulon; pfam02453
Reticulon; pfam02453
Reticulon; pfam02453
Reticulon; pfam02453
Reticulon; pfam02453
Clathrin-H-link; pfam13838
Clathrin-H-link; pfam13838
Ubiquitin; cd01803
Ubiquitin homologues; smart00213
Ribosomal protein S27a; pfam01599
Ubiquitin; cd01803
Ubiquitin homologues; smart00213
Ribosomal protein S27a; pfam01599
Ubiquitin; cd01803
Ubiquitin homologues; smart00213
Ribosomal protein S27a; pfam01599
Translation initiation factor 2 (IF-2; GTPase) [Translation, ribosomal structure and biogenesis]; COG0532
Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; cd01887
This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; cd03702
Translation-initiation factor 2; pfam11987
mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; cd03692
Translation initiation factor 2 (IF-2; GTPase) [Translation, ribosomal structure and biogenesis]; COG0532
Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; cd01887
This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; cd03702
Translation-initiation factor 2; pfam11987
mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; cd03692
HOOK protein; pfam05622
HOOK protein; pfam05622
HOOK protein; pfam05622
The ARF-like 2 binding protein BART; pfam11527
Pleckstrin homology-like domain; cl00273
Component of IIS longevity pathway SMK-1; pfam04802
Pleckstrin homology-like domain; cl00273
Component of IIS longevity pathway SMK-1; pfam04802
polynucleotide phosphorylase/polyadenylase; Provisional
Polyribonucleotide nucleotidyltransferase, repeat 1; cd11363
Polyribonucleotide nucleotidyltransferase, RNA binding domain; pfam03726
Polyribonucleotide nucleotidyltransferase, repeat 2; cd11364
Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; cd02393
Ribosomal protein S1-like RNA-binding domain; smart00316
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain; smart00179
Uncharacterized conserved proteins (DUF2216); pfam10226
putative serine/threonine kinase; Provisional
Catalytic domain of Protein Kinases; cd00180
putative serine/threonine kinase; Provisional
Catalytic domain of Protein Kinases; cd00180
putative serine/threonine kinase; Provisional
Catalytic domain of Protein Kinases; cd00180
putative serine/threonine kinase; Provisional
Catalytic domain of Protein Kinases; cd00180
putative serine/threonine kinase; Provisional
Catalytic domain of Protein Kinases; cd00180
WD-repeat region; pfam09765
FANCL C-terminal domain; pfam11793
WD-repeat region; pfam09765
FANCL C-terminal domain; pfam11793
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Poly(A) polymerase central domain; pfam04928
Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases; cd05402
Poly(A) polymerase predicted RNA binding domain; pfam04926
N-terminal sub-domain of the Rel homology domain (RHD) of c-Rel; cd07933
IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to...; cd01177
putative pseudouridylate synthase; Provisional
Peroxin 13, N-terminal region; pfam04088
Src Homology 3 domain of eumetazoan Peroxisomal biogenesis factor 13; cd11864
Domain of unknown function (DUF3342); pfam11822
Domain of unknown function (DUF3342); pfam11822
START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; cl14643
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02659
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Importin beta-related nuclear transport receptor [Nuclear structure / Intracellular trafficking and secretion]; COG5101
Importin-beta N-terminal domain; smart00913
Exportin 1-like protein; pfam08389
CRM1 C terminal; smart01102
Uncharacterized protein family UPF0564; pfam10595
Uncharacterized protein family UPF0564; pfam10595
T-complex protein 1, delta subunit; TIGR02342
TCP-1 (CTT or eukaryotic type II) chaperonin family, delta subunit. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings. In contrast to bacterial group I chaperonins; cd03338
T-complex protein 1, delta subunit; TIGR02342
TCP-1 (CTT or eukaryotic type II) chaperonin family, delta subunit. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings. In contrast to bacterial group I chaperonins; cd03338
COMM_Domain containing protein 1, also called Murr1. Murr1/Commd1 is a protein involved in copper homeostasis, which has also been identified as a regulator of the human delta epithelial sodium channel. The COMM Domain is found at the C-terminus of a...; cd04749
Galactosyltransferase; cl09537
Predicted membrane protein; pfam09799
N-terminal C2 in EEIG1 and EHBP1 proteins; pfam10358
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Protein of unknown function (DUF3585); pfam12130
N-terminal C2 in EEIG1 and EHBP1 proteins; pfam10358
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Protein of unknown function (DUF3585); pfam12130
N-terminal C2 in EEIG1 and EHBP1 proteins; pfam10358
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Protein of unknown function (DUF3585); pfam12130
N-terminal C2 in EEIG1 and EHBP1 proteins; pfam10358
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Protein of unknown function (DUF3585); pfam12130
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Otx1 transcription factor; pfam03529
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Otx1 transcription factor; pfam03529
Protein of unknown function (DUF3312); pfam11768
malate dehydrogenase; TIGR01759
Cytoplasmic and cytosolic Malate dehydrogenases; cd01336
malate dehydrogenase; TIGR01759
Cytoplasmic and cytosolic Malate dehydrogenases; cd01336
Cytoplasmic and cytosolic Malate dehydrogenases; cd01336
UDP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]
Eukaryotic UGPase catalyses the synthesis of UDP-Glucose; cd00897
UDP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]
Eukaryotic UGPase catalyses the synthesis of UDP-Glucose; cd00897
Vps54-like protein; pfam07928
Vps54-like protein; pfam07928
Pellino; pfam04710
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
SERTA motif; pfam06031
Sodium:dicarboxylate symporter family; pfam00375
Na+/H+-dicarboxylate symporters [Energy production and conversion]; COG1301
Na+/H+-dicarboxylate symporters [Energy production and conversion]; COG1301
Sodium:dicarboxylate symporter family; pfam00375
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Rab family protein; Provisional
Rab GTPase family 1 includes the yeast homolog Ypt1; cd01869
Actin; smart00268
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Actin; smart00268
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
EVH1 (Enabled, Vasp-Homology) or WASP Homology (WH1) domain; cd00837
Sprouty protein (Spry); pfam05210
EVH1 (Enabled, Vasp-Homology) or WASP Homology (WH1) domain; cd00837
Sprouty protein (Spry); pfam05210
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Sas10/Utp3/C1D family; pfam04000
Sas10/Utp3/C1D family; pfam04000
Sas10/Utp3/C1D family; pfam04000
Sas10/Utp3/C1D family; pfam04000
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Predicted RNA-binding protein (contains KH domains) [General function prediction only]
KH domain; pfam00013
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Predicted membrane protein (DUF2207); pfam09972
Predicted membrane protein (DUF2207); pfam09972
Pleckstrin homology (PH) domain; cd00821
DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in pleckstrin 1-like proteins.  Pleckstrin 1 plays a role in cell spreading and reorganization of actin cytoskeleton in platelets and leukocytes. Its activity is highly regulated by phosphorylation; cd04445
Pleckstrin homology (PH) domain; cd00821
F-box-like; pfam12937
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cl00062
Zinc-finger (CX5CX6HX5H) motif; pfam10283
Zinc-finger (CX5CX6HX5H) motif; pfam10283
7 transmembrane receptor (rhodopsin family); pfam00001
Pleckstrin homology (PH) domain; cd00821
RhoGAP_ARHGAP22_24_25:  GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been...; cd04390
GTPase-activator protein for Rho-like GTPases; smart00324
Pleckstrin homology (PH) domain; cd00821
RhoGAP_ARHGAP22_24_25:  GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been...; cd04390
GTPase-activator protein for Rho-like GTPases; smart00324
Pleckstrin homology (PH) domain; cd00821
RhoGAP_ARHGAP22_24_25:  GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been...; cd04390
GTPase-activator protein for Rho-like GTPases; smart00324
Pleckstrin homology (PH) domain; cd00821
RhoGAP_ARHGAP22_24_25:  GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been...; cd04390
GTPase-activator protein for Rho-like GTPases; smart00324
TGF-beta propeptide; pfam00688
Transforming growth factor-beta (TGF-beta) family; smart00204
BRICHOS domain; pfam04089
BRICHOS domain; pfam04089
ATR (Anthrax Toxin Receptor): Anthrax toxin is a key virulence factor for Bacillus anthracis, the causative agent of anthrax. ATR is the cellular receptor for the anthrax protective antigen and facilitates entry of the toxin into cells. The VWA domain in...; cd01474
Anthrax receptor extracellular domain; pfam05587
Anthrax receptor C-terminus region; pfam05586
ATR (Anthrax Toxin Receptor): Anthrax toxin is a key virulence factor for Bacillus anthracis, the causative agent of anthrax. ATR is the cellular receptor for the anthrax protective antigen and facilitates entry of the toxin into cells. The VWA domain in...; cd01474
Anthrax receptor extracellular domain; pfam05587
ATR (Anthrax Toxin Receptor): Anthrax toxin is a key virulence factor for Bacillus anthracis, the causative agent of anthrax. ATR is the cellular receptor for the anthrax protective antigen and facilitates entry of the toxin into cells. The VWA domain in...; cd01474
Anthrax receptor extracellular domain; pfam05587
glucosamine:fructose-6-phosphate aminotransferase
Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; cd00714
SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; cd05008
SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; cd05009
glucosamine:fructose-6-phosphate aminotransferase
Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; cd00714
Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; cl00319
SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; cd05008
SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; cd05009
Scaffold protein Nfu/NifU N terminal; pfam08712
Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]
Scaffold protein Nfu/NifU N terminal; pfam08712
Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]
Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
Annexin; pfam00191
BTB/POZ domain; pfam00651
BTB And C-terminal Kelch; smart00875
Protein of unknown function (DUF1777); pfam08648
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cl00081
Retropepsins; pepsin-like aspartate proteases; cd00303
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
Transcription elongation factor [Transcription]; COG0195
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Prenylcysteine lyase; pfam07156
Sm protein G; cd01719
Eukaryotic protein of unknown function (DUF842); pfam05811
EGF-like protein; Provisional
EGF-like protein; Provisional
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); cd00398
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
V-type (H+)-ATPase V1, B subunit; TIGR01040
ATP synthase alpha/beta family, beta-barrel domain; pfam02874
V/A-type ATP synthase (non-catalytic) subunit B. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; cd01135
ATP synthase alpha/beta chain, C terminal domain; pfam00306
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Transmembrane adaptor Erv26; pfam04148
BadF/BadG/BcrA/BcrD ATPase family; pfam01869
Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; pfam00903
Methylmalonyl-CoA epimerase (MMCE); cd07249
Mpp10 protein; pfam04006
U3 small nucleolar ribonucleoprotein component [Translation, ribosomal structure and biogenesis]; COG5384
Ataxin-2 C-terminal region; pfam07145
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); pfam13893
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); pfam13893
U1-like zinc finger; smart00451
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); pfam13893
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); pfam13893
U1-like zinc finger; smart00451
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); pfam13893
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); pfam13893
U1-like zinc finger; smart00451
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); pfam13893
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); pfam13893
C2 domain first repeat in Ferlin; cd08373
C2 domain second repeat in Ferlin; cd04011
FerI (NUC094) domain; pfam08151
C2 domain third repeat in Ferlin; cd04018
FerA (NUC095) domain; pfam08165
FerB (NUC096) domain; pfam08150
Dysferlin domain, N-terminal region; smart00693
Dysferlin domain, N-terminal region; smart00693
C2 domain fourth repeat in Ferlin; cd04017
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
C2 domain first repeat in Ferlin; cd08373
C2 domain second repeat in Ferlin; cd04011
FerI (NUC094) domain; pfam08151
C2 domain third repeat in Ferlin; cd04018
FerA (NUC095) domain; pfam08165
FerB (NUC096) domain; pfam08150
Dysferlin domain, N-terminal region; smart00693
Dysferlin domain, N-terminal region; smart00693
C2 domain fourth repeat in Ferlin; cd04017
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
C2 domain first repeat in Ferlin; cd08373
C2 domain second repeat in Ferlin; cd04011
FerI (NUC094) domain; pfam08151
C2 domain third repeat in Ferlin; cd04018
FerA (NUC095) domain; pfam08165
FerB (NUC096) domain; pfam08150
Dysferlin domain, N-terminal region; smart00693
Dysferlin domain, N-terminal region; smart00693
C2 domain fourth repeat in Ferlin; cd04017
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
C2 domain first repeat in Ferlin; cd08373
C2 domain second repeat in Ferlin; cd04011
FerI (NUC094) domain; pfam08151
C2 domain third repeat in Ferlin; cd04018
FerA (NUC095) domain; pfam08165
FerB (NUC096) domain; pfam08150
Dysferlin domain, N-terminal region; smart00693
Dysferlin domain, N-terminal region; smart00693
C2 domain fourth repeat in Ferlin; cd04017
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
C2 domain first repeat in Ferlin; cd08373
C2 domain second repeat in Ferlin; cd04011
FerI (NUC094) domain; pfam08151
C2 domain third repeat in Ferlin; cd04018
FerA (NUC095) domain; pfam08165
FerB (NUC096) domain; pfam08150
Dysferlin domain, N-terminal region; smart00693
Dysferlin domain, N-terminal region; smart00693
C2 domain fourth repeat in Ferlin; cd04017
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
C2 domain first repeat in Ferlin; cd08373
C2 domain second repeat in Ferlin; cd04011
FerI (NUC094) domain; pfam08151
C2 domain third repeat in Ferlin; cd04018
FerA (NUC095) domain; pfam08165
FerB (NUC096) domain; pfam08150
Dysferlin domain, N-terminal region; smart00693
Dysferlin domain, N-terminal region; smart00693
C2 domain fourth repeat in Ferlin; cd04017
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
C2 domain first repeat in Ferlin; cd08373
C2 domain second repeat in Ferlin; cd04011
FerI (NUC094) domain; pfam08151
C2 domain third repeat in Ferlin; cd04018
FerA (NUC095) domain; pfam08165
FerB (NUC096) domain; pfam08150
Dysferlin domain, N-terminal region; smart00693
Dysferlin domain, N-terminal region; smart00693
C2 domain fourth repeat in Ferlin; cd04017
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
C2 domain first repeat in Ferlin; cd08373
C2 domain second repeat in Ferlin; cd04011
FerI (NUC094) domain; pfam08151
C2 domain third repeat in Ferlin; cd04018
FerA (NUC095) domain; pfam08165
FerB (NUC096) domain; pfam08150
Dysferlin domain, N-terminal region; smart00693
Dysferlin domain, N-terminal region; smart00693
C2 domain fourth repeat in Ferlin; cd04017
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
C2 domain first repeat in Ferlin; cd08373
C2 domain second repeat in Ferlin; cd04011
FerI (NUC094) domain; pfam08151
C2 domain third repeat in Ferlin; cd04018
FerA (NUC095) domain; pfam08165
FerB (NUC096) domain; pfam08150
Dysferlin domain, N-terminal region; smart00693
Dysferlin domain, N-terminal region; smart00693
C2 domain fourth repeat in Ferlin; cd04017
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
C2 domain first repeat in Ferlin; cd08373
C2 domain second repeat in Ferlin; cd04011
FerI (NUC094) domain; pfam08151
C2 domain third repeat in Ferlin; cd04018
FerA (NUC095) domain; pfam08165
FerB (NUC096) domain; pfam08150
Dysferlin domain, N-terminal region; smart00693
Dysferlin domain, N-terminal region; smart00693
C2 domain fourth repeat in Ferlin; cd04017
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
C2 domain first repeat in Ferlin; cd08373
C2 domain second repeat in Ferlin; cd04011
FerI (NUC094) domain; pfam08151
C2 domain third repeat in Ferlin; cd04018
FerA (NUC095) domain; pfam08165
FerB (NUC096) domain; pfam08150
Dysferlin domain, N-terminal region; smart00693
Dysferlin domain, N-terminal region; smart00693
C2 domain fourth repeat in Ferlin; cd04017
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
C2 domain first repeat in Ferlin; cd08373
C2 domain second repeat in Ferlin; cd04011
FerI (NUC094) domain; pfam08151
C2 domain third repeat in Ferlin; cd04018
FerA (NUC095) domain; pfam08165
FerB (NUC096) domain; pfam08150
Dysferlin domain, N-terminal region; smart00693
Dysferlin domain, N-terminal region; smart00693
C2 domain fourth repeat in Ferlin; cd04017
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
C2 domain first repeat in Ferlin; cd08373
C2 domain second repeat in Ferlin; cd04011
FerI (NUC094) domain; pfam08151
C2 domain third repeat in Ferlin; cd04018
FerA (NUC095) domain; pfam08165
FerB (NUC096) domain; pfam08150
Dysferlin domain, N-terminal region; smart00693
Dysferlin domain, N-terminal region; smart00693
C2 domain fourth repeat in Ferlin; cd04017
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
C2 domain first repeat in Ferlin; cd08373
C2 domain second repeat in Ferlin; cd04011
FerI (NUC094) domain; pfam08151
C2 domain third repeat in Ferlin; cd04018
FerA (NUC095) domain; pfam08165
FerB (NUC096) domain; pfam08150
Dysferlin domain, N-terminal region; smart00693
Dysferlin domain, N-terminal region; smart00693
C2 domain fourth repeat in Ferlin; cd04017
C2 domain fifth repeat in Ferlin; cd04037
C2 domain sixth repeat in Ferlin; cd08374
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Exocyst complex subunit Sec15-like; pfam04091
sepiapterin reductase; TIGR01500
sepiapterin reductase (SPR)-like, classical (c) SDRs; cd05367
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Tricarboxylate carrier; cl04275
C2 domain found in Rab11-family interacting proteins (FIP) class I; cd08682
FIP domain; pfam09457
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
PA_hPAP21_like: Protease-associated domain containing proteins like the human secreted glycoprotein hPAP21 (human protease-associated domain-containing protein, 21kDa). This group contains various PA domain-containing proteins similar to hPAP21. Complex...; cd02127
T-complex protein 1, eta subunit; TIGR02345
TCP-1 (CTT or eukaryotic type II) chaperonin family, eta subunit. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings. In contrast to bacterial group I chaperonins (GroEL); cd03340
TCP-1 (CTT or eukaryotic type II) chaperonin family, eta subunit. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings. In contrast to bacterial group I chaperonins (GroEL); cd03340
chaperonin_like superfamily. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. There are 2 main chaperonin groups. The symmetry of type I...; cl02777
TCP-1 (CTT or eukaryotic type II) chaperonin family, eta subunit. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings. In contrast to bacterial group I chaperonins (GroEL); cd03340
T-complex protein 1, eta subunit; TIGR02345
F-box-like; pfam12937
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Acetyltransferases [General function prediction only]; COG0456
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; cd04301
Acetyltransferases [General function prediction only]; COG0456
Kinase binding protein CGI-121; pfam08617
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cl00053
large tegument protein UL36; Provisional
Domain of unknown function (DUF1873); pfam08969
Mov34/MPN/PAD-1 family; cd08066
Domain of unknown function (DUF1873); pfam08969
Mov34/MPN/PAD-1 family; cd08066
Domain of unknown function (DUF1873); pfam08969
Mov34/MPN/PAD-1 family; cd08066
Actin; pfam00022
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Actin; pfam00022
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Deoxynucleoside kinases [Nucleotide transport and metabolism]
Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; cd01673
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Oxygenase domain of the 2OGFeDO superfamily; pfam12851
Oxygenase domain of the 2OGFeDO superfamily; pfam12851
BolA-like protein; pfam01722
Mob1/phocein family; pfam03637
bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional
Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; pfam00763
NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; cd01080
anion exchange protein; TIGR00834
HCO3- transporter family; pfam00955
anion exchange protein; TIGR00834
HCO3- transporter family; pfam00955
CAP-Gly domain; pfam01302
Dynein associated protein; pfam12455
TATA element modulatory factor 1 DNA binding; pfam12329
CAP-Gly domain; pfam01302
Dynein associated protein; pfam12455
TATA element modulatory factor 1 DNA binding; pfam12329
CAP-Gly domain; pfam01302
Dynein associated protein; pfam12455
TATA element modulatory factor 1 DNA binding; pfam12329
CAP-Gly domain; pfam01302
Dynein associated protein; pfam12455
TATA element modulatory factor 1 DNA binding; pfam12329
Dynein associated protein; pfam12455
Dynein associated protein; pfam12455
TATA element modulatory factor 1 DNA binding; pfam12329
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Rho effector or protein kinase C-related kinase homology region 1 homologues; smart00742
Cell division protein anillin; pfam08174
Pleckstrin homology (PH) domain; cd00821
Rho effector or protein kinase C-related kinase homology region 1 homologues; smart00742
Cell division protein anillin; pfam08174
Pleckstrin homology (PH) domain; cd00821
Rho effector or protein kinase C-related kinase homology region 1 homologues; smart00742
Cell division protein anillin; pfam08174
Pleckstrin homology (PH) domain; cd00821
PAPA-1-like conserved region; pfam04795
HIT zinc finger; pfam04438
WW domain-binding protein 1; pfam11669
Mannosyl oligosaccharide glucosidase; pfam03200
Mannosyl oligosaccharide glucosidase; pfam03200
39S ribosomal protein L53/MRP-L53; pfam10780
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13432
TPR repeat; pfam13414
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
DEAD-like helicases superfamily; smart00487
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Oligonucleotide/oligosaccharide-binding (OB)-fold; pfam07717
N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; cl00357
Domain that may be involved in binding ubiquitin-conjugating enzymes (UBCs); smart00546
Trypsin-like peptidase domain; pfam13365
PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; cd00987
Trypsin-like peptidase domain; pfam13365
PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; cd00989
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Scavenger receptor Cys-rich; smart00202
Lysyl oxidase; pfam01186
PH domain; pfam00169
Downstream of tyrosine kinase  (DOK) Phosphotyrosine-binding domain; cd01203
Downstream of tyrosine kinase  (DOK) Phosphotyrosine-binding domain; cd01203
The Sema domain, a protein interacting module, of semaphorin 4F (Sema4F); cd11261
semaphorin domain; smart00630
Plexin repeat; pfam01437
Immunoglobulin (Ig)-like domain of the class IV semaphorin Sema4B; cd05872
hexokinase; Provisional
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Hexokinase; pfam03727
hexokinase; Provisional
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Hexokinase; pfam03727
Histone-like transcription factor (CBF/NF-Y) and archaeal histone; pfam00808
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
Ribosomal protein L19; pfam01245
GC-rich sequence DNA-binding factor-like protein; pfam07842
GC-rich sequence DNA-binding factor-like protein; pfam07842
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
C-type lectin-like domain (CTLD) of the type found in Human REG-1 (lithostathine), REG-4, and avian eggshell-specific proteins: ansocalcin, structhiocalcin-1(SCA-1), and -2(SCA-2); cd03594
C-type lectin-like domain (CTLD) of the type found in Human REG-1 (lithostathine), REG-4, and avian eggshell-specific proteins: ansocalcin, structhiocalcin-1(SCA-1), and -2(SCA-2); cd03594
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
C-type lectin-like domain (CTLD) of the type found in Human REG-1 (lithostathine), REG-4, and avian eggshell-specific proteins: ansocalcin, structhiocalcin-1(SCA-1), and -2(SCA-2); cd03594
C-type lectin-like domain (CTLD) of the type found in Human REG-1 (lithostathine), REG-4, and avian eggshell-specific proteins: ansocalcin, structhiocalcin-1(SCA-1), and -2(SCA-2); cd03594
C-type lectin-like domain (CTLD) of the type found in Human REG-1 (lithostathine), REG-4, and avian eggshell-specific proteins: ansocalcin, structhiocalcin-1(SCA-1), and -2(SCA-2); cd03594
C-type lectin-like domain (CTLD) of the type found in Human REG-1 (lithostathine), REG-4, and avian eggshell-specific proteins: ansocalcin, structhiocalcin-1(SCA-1), and -2(SCA-2); cd03594
C-type lectin-like domain (CTLD) of the type found in Human REG-1 (lithostathine), REG-4, and avian eggshell-specific proteins: ansocalcin, structhiocalcin-1(SCA-1), and -2(SCA-2); cd03594
Vinculin family; pfam01044
Vinculin family; pfam01044
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
succinyl-CoA synthetase alpha subunit; Provisional
CoA binding domain; pfam02629
CoA-ligase; cl02894
Dynein heavy chain, N-terminal region 2; pfam08393
Hydrolytic ATP binding site of dynein motor region D1; pfam12774
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Microtubule-binding stalk of dynein motor; pfam12777
ATP-binding dynein motor region D5; pfam12781
Dynein heavy chain and region D6 of dynein motor; pfam03028
TraB family; pfam01963
Thymosin beta-4 family; pfam01290
Zinc finger, ZZ type. Zinc finger present in potassium channel modulatory factor (PCMF) 1  and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Human potassium channel...; cd02338
Drought induced 19 protein (Di19); pfam05605
N-terminal CTNNB1 binding; pfam08347
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
DNA topoisomerase 2; Provisional
DNA topoisomerase 2; Provisional
K+-dependent Na+/Ca+ exchanger; TIGR00927
DNA topoisomerase 2; Provisional
Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]
NAD(P)-binding Rossmann-like domain; pfam13450
ELMO/CED-12 family; pfam04727
ELMO/CED-12 family; pfam04727
ELMO/CED-12 family; pfam04727
ELMO/CED-12 family; pfam04727
Gelsolin sub-domain 1-like domain found in gelsolin, severin, villin, and related proteins; cd11290
Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins; cd11289
Gelsolin sub-domain 3-like domain found in gelsolin, severin, villin, and related proteins; cd11292
Gelsolin sub-domain 1-like domain found in gelsolin, severin, villin, and related proteins; cd11290
Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins; cd11289
Gelsolin sub-domain 3-like domain found in gelsolin, severin, villin, and related proteins; cd11292
Gelsolin sub-domain 1-like domain found in gelsolin, severin, villin, and related proteins; cd11290
Gelsolin sub-domain 2-like domain found in gelsolin, severin, villin, and related proteins; cd11289
Gelsolin sub-domain 3-like domain found in gelsolin, severin, villin, and related proteins; cd11292
Src homology 2 (SH2) domain found in B-cell linker (BLNK) protein and SH2 domain-containing leukocyte protein of 76 kDa (SLP-76); cd09929
S-adenosylmethionine synthase; Provisional
S-adenosylmethionine synthetase, N-terminal domain; pfam00438
S-adenosylmethionine synthetase, central domain; pfam02772
S-adenosylmethionine synthetase, C-terminal domain; pfam02773
Vitamin K-dependent gamma-carboxylase; pfam05090
Vitamin K-dependent gamma-carboxylase; pfam05090
Synaptobrevin; pfam00957
Synaptobrevin; pfam00957
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Frag1/DRAM/Sfk1 family; pfam10277
Uncharacterized protein family UPF0561; pfam10573
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02669
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02669
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02669
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02669
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02669
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Saposin A-type domain; cl02494
Saposin-like type B, region 1; pfam05184
Saposin (B) Domains; smart00741
Saposin-like type B, region 2; pfam03489
Saposin (B) Domains; smart00741
Saposin (B) Domains; smart00741
Saposin-like type B, region 2; pfam03489
Saposin A-type domain; cl02494
Saposin-like type B, region 1; pfam05184
Saposin (B) Domains; smart00741
Saposin-like type B, region 2; pfam03489
Saposin (B) Domains; smart00741
Saposin (B) Domains; smart00741
Saposin-like type B, region 2; pfam03489
Saposin (B) Domains; smart00741
Saposin-like type B, region 2; pfam03489
Saposin (B) Domains; smart00741
Saposin-like type B, region 2; pfam03489
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
DNA-directed RNA polymerase subunit A'; TIGR02390
RNA polymerase Rpb1, domain 1; pfam04997
RNA polymerase I subunit A N-terminus; smart00663
RNA polymerase Rpb1, domain 3; pfam04983
RNA polymerase Rpb1, domain 4; pfam05000
RNA polymerase Rpb1, domain 5; pfam04998
Largest subunit of RNA polymerase (RNAP), C-terminal domain; cl11429
Largest subunit (Rpa1) of Eukaryotic RNA polymerase I (RNAP I), C-terminal domain; cd02735
PPR repeat family; pfam13041
PPR repeat family; pfam13041
PPR repeat; cl03252
Mitochondrial inner membrane protein; pfam09731
Mitochondrial inner membrane protein; pfam09731
Mitochondrial inner membrane protein; pfam09731
Ribosomal protein L35; pfam01632
Ribosomal protein L35; pfam01632
TB2/DP1, HVA22 family; pfam03134
TB2/DP1, HVA22 family; pfam03134
TB2/DP1, HVA22 family; pfam03134
TB2/DP1, HVA22 family; pfam03134
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
Snf7; pfam03357
Snf7; cl02305
Snf7; pfam03357
Snf7; pfam03357
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Lissencephaly type-1-like homology motif; smart00667
CTLH/CRA C-terminal to LisH motif domain; pfam10607
C-terminal to LisH motif; smart00668
CT11-RanBPM; smart00757
RING-type zinc-finger, LisH dimerisation motif; pfam13445
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig) like domain of CD8 alpha chain; cd05720
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig) like domain of CD8 alpha chain; cd05720