ATPases associated with a variety of cellular activities; smart00382
Vps4 C terminal oligomerisation domain; pfam09336
Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; cd00487
Dor1-like family; pfam04124
Protein involved in ribosomal biogenesis, contains PUA domain [Translation, ribosomal structure and biogenesis]; COG1374
PUA domain; cl00607
emp24/gp25L/p24 family/GOLD; pfam01105
Telomeric Repeat binding Factor or TTAGGG Repeat binding Factor, central (dimerization) domain Homology; TRFH. Telomeres are protein/DNA complexes that make up the physical ends of eukaryotic linear chromosomes and are essential for chromosome stability; cd00280
RAP1 binding motif of telomere repeat binding factor; cd11654
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; cd11660
Cytochrome b5-like Heme/Steroid binding domain; pfam00173
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; cl00200
N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP); cd07882
IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction; cd01178
N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP); cd07882
IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction; cd01178
N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP); cd07882
IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction; cd01178
N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP); cd07882
IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction; cd01178
N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP); cd07882
IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction; cd01178
N-terminal sub-domain of the Rel homology domain (RHD) of tonicity-responsive enhancer binding protein (TonEBP); cd07882
IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction; cd01178
Flavodoxin-like fold; pfam02525
Flavodoxin-like fold; pfam02525
Flavodoxin-like fold; pfam02525
PIN domain of eukaryotic ribosome assembly factor Nob1 and archaeal UPF0129 protein Ta0041-like homologs; cd09876
Nin one binding (NOB1) Zn-ribbon like; pfam08772
C2 domain present in E3 ubiquitin ligase; cd04021
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
C2 domain present in E3 ubiquitin ligase; cd04021
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
C2 domain present in E3 ubiquitin ligase; cd04021
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
C2 domain; cl14603
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
SCP_euk: SCP-like extracellular protein domain, as found mainly in eukaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5 from vespid venom. It has been proposed...; cd05380
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
SCP_euk: SCP-like extracellular protein domain, as found mainly in eukaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5 from vespid venom. It has been proposed...; cd05380
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
SCP_euk: SCP-like extracellular protein domain, as found mainly in eukaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5 from vespid venom. It has been proposed...; cd05380
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
FAD dependent oxidoreductase; pfam01266
Glycine cleavage system T protein (aminomethyltransferase) [Amino acid transport and metabolism]; COG0404
Glycine cleavage T-protein C-terminal barrel domain; pfam08669
SCP_euk: SCP-like extracellular protein domain, as found mainly in eukaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5 from vespid venom. It has been proposed...; cd05380
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
MTR3 subunit of eukaryotic exosome; cd11371
alanyl-tRNA synthetase
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of...; cd00673
Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; cl02787
Threonyl and Alanyl tRNA synthetase second additional domain; pfam07973
DHHA1 domain; pfam02272
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
helicase 45; Provisional
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; COG0513
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
DEAD-like helicases superfamily; smart00487
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
DEAD-like helicases superfamily; smart00487
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
DEAD-like helicases superfamily; smart00487
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; COG0513
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
helicase 45; Provisional
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Glycosyltransferase family 29 (sialyltransferase); pfam00777
L-fucokinase; pfam07959
COG4 transport protein; smart00762
COG4 transport protein; smart00762
Mono-functional DNA-alkylating methyl methanesulfonate N-term; pfam10433
CPSF A subunit region; pfam03178
Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Missing In Metastasis; cd07643
IRSp53/MIM homology domain; pfam08397
Vacuolar 14 Fab1-binding region; pfam12755
Vacuolar protein 14 C-terminal Fig4p binding; pfam11916
MSP (Major sperm protein) domain; pfam00635
MSP (Major sperm protein) domain; pfam00635
MSP (Major sperm protein) domain; pfam00635
FtsJ-like methyltransferase; pfam01728
FtsJ-like methyltransferase; pfam01728
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Sulfotransferase domain; pfam00685
Sulfotransferase domain; pfam00685
Aminotransferase ubiquitination site; pfam07706
tyrosine aminotransferase, eukaryotic; TIGR01264
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; cd00609
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine Rich repeats (2 copies); pfam12799
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; cd00143
Adaptin N terminal region; pfam01602
Adaptin C-terminal domain; pfam02883
Adaptin N terminal region; pfam01602
Adaptin C-terminal domain; pfam02883
Ataxin-1 and HBP1 module (AXH); pfam08517
Regulator of Vps4 activity in the MVB pathway; pfam03398
Regulator of Vps4 activity in the MVB pathway; pfam03398
Regulator of Vps4 activity in the MVB pathway; pfam03398
Regulator of Vps4 activity in the MVB pathway; pfam03398
Regulator of Vps4 activity in the MVB pathway; pfam03398
Regulator of Vps4 activity in the MVB pathway; pfam03398
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
Latrophilin/CL-1-like GPS domain; pfam01825
PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological...; cd01752
Polycystin cation channel; pfam08016
dihydroorotate dehydrogenase, subfamily 2; TIGR01036
Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; cd04738
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Dim1 family, Dim1-like protein (DLP) subfamily; DLP is a novel protein which shares 38% sequence identity to Dim1. Like Dim1, it is also implicated in pre-mRNA splicing and cell cycle progression. DLP is located in the nucleus and has been shown to...; cd02986
Dim1 family, Dim1-like protein (DLP) subfamily; DLP is a novel protein which shares 38% sequence identity to Dim1. Like Dim1, it is also implicated in pre-mRNA splicing and cell cycle progression. DLP is located in the nucleus and has been shown to...; cd02986
Dim1 family, Dim1-like protein (DLP) subfamily; DLP is a novel protein which shares 38% sequence identity to Dim1. Like Dim1, it is also implicated in pre-mRNA splicing and cell cycle progression. DLP is located in the nucleus and has been shown to...; cd02986
DEAD-like helicases superfamily; smart00487
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Helicase associated domain (HA2); pfam04408
Oligonucleotide/oligosaccharide-binding (OB)-fold; pfam07717
chromosome segregation protein SMC, common bacterial type; TIGR02168
chromosome segregation protein SMC, common bacterial type; TIGR02168
chromosome segregation protein SMC, common bacterial type; TIGR02168
chromosome segregation protein SMC, common bacterial type; TIGR02168
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain-containing transcription factor [Transcription]
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain-containing transcription factor [Transcription]
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Mpr1p, Pad1p N-terminal (MPN) domains without catalytic isopeptidase activity, found in 19S proteasomal subunits Rpn7 and Rpn8; cd08062
SCP_euk: SCP-like extracellular protein domain, as found mainly in eukaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5 from vespid venom. It has been proposed...; cd05380
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Cysteine rich repeat; pfam00839
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Protein Kinases, catalytic domain; cl09925
hypothetical protein; Provisional
Protein Kinases, catalytic domain; cl09925
Cytochrome b5-like Heme/Steroid binding domain; pfam00173
Fatty acid hydroxylase superfamily; cl01132
Sterol desaturase [Lipid metabolism]; COG3000
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
domain in RING finger and WD repeat containing proteins and DEXDc-like helicases subfamily related to the UBCc domain; smart00591
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cl15348
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
FAD binding domain; pfam01565
glycolate oxidase, subunit GlcD; TIGR00387
FAD binding domain; pfam01565
glycolate oxidase, subunit GlcD; TIGR00387
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1; cd12001
Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module; cl07433
C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module; cd11569
Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1; cd12001
Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module; cl07433
C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module; cd11569
Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1; cd12001
Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module; cl07433
C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module; cd11569
Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1; cd12001
Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module; cl07433
C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module; cd11569
Src Homology 3 domain superfamily; cl17036
Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module; cl07433
C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module; cd11569
Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1; cd12001
Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module; cl07433
C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module; cd11569
Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1; cd12001
Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module; cl07433
C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module; cd11569
Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1; cd12001
Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module; cl07433
C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module; cd11569
Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module; cl07433
C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module; cd11569
Bucentaur or craniofacial development; pfam07572
Putative transmembrane protein 170; pfam10190
Sulfotransferase domain; pfam00685
Sulfotransferase domain; pfam00685
Transmembrane protein 231; pfam10149
Transmembrane protein 231; pfam10149
Transmembrane protein 231; pfam10149
Ubiquitin domain of GABA-receptor-associated protein; cd01611
Adenosine-deaminase (editase) domain; cl02661
Adenosine-deaminase (editase) domain; cl02661
lysyl-tRNA synthetase
LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; cd04322
Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; cd00775
lysyl-tRNA synthetase
LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; cd04322
Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; cd00775
DNA-binding modules of yeast Rap1 and related proteins; cd11655
C-terminal domain of RAP1 recruits proteins to telomeres; cd11653
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cl00085
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Fibrillar collagen C-terminal domain; cl02436
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Trafficking protein Mon1; pfam03164
chromosome segregation protein SMC, primarily archaeal type; TIGR02169
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that...; cd04273
Thrombospondin type 1 repeats; smart00209
ADAM-TS Spacer 1; pfam05986
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
Thrombospondin type 1 repeats; smart00209
PLAC (protease and lacunin) domain; pfam08686
Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; cd03426
Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; cd03426
Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; cl00447
Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; cd03426
Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; cd08275
Enoylreductase; smart00829
C-type lectin-like domain (CTLD) of the type found in the tetranectin (TN), cartilage derived C-type lectin (CLECSF1), and stem cell growth factor (SCGF); cd03596
C-type lectin-like domain (CTLD) of the type found in the tetranectin (TN), cartilage derived C-type lectin (CLECSF1), and stem cell growth factor (SCGF); cd03596
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
oxidoreductase; Provisional
human WWOX (WW domain-containing oxidoreductase)-like, classical (c)-like SDRs; cd09809
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cl00157
Maf N-terminal region; pfam08383
bZIP Maf transcription factor; pfam03131
Maf N-terminal region; pfam08383
bZIP Maf transcription factor; pfam03131
Roadblock/LC7 domain; pfam03259
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; COG1024
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; cd06558
Cytochrome c oxidase biogenesis protein Cmc1 like; pfam08583
Kinetochore protein CHL4 like; pfam05238
Kinetochore protein CHL4 like; pfam05238
Kinetochore protein CHL4 like; pfam05238
Kinetochore protein CHL4 like; pfam05238
Kinetochore protein CHL4 like; pfam05238
Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; cd06848
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
Galactose binding lectin domain; pfam02140
REJ domain; pfam02010
Latrophilin/CL-1-like GPS domain; pfam01825
PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological...; cd01752
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
Galactose binding lectin domain; pfam02140
REJ domain; pfam02010
Retinal pigment epithelial membrane protein; pfam03055
Lignostilbene-alpha,beta-dioxygenase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
PH domain; pfam00169
Antagonist of mitotic exit network protein 1; cl15308
Antagonist of mitotic exit network protein 1; cl15308
Phospholipase C (PLC) pleckstrin homology (PH) domain; cd01248
Phosphoinositide-specific phospholipase C, efhand-like; pfam09279
Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma; cd08592
N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma; cd10341
C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma; cd09932
Src homology 3 domain of Phospholipase C (PLC) gamma 2; cd11969
Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; cl14615
C2 domain present in Phosphoinositide-specific phospholipases C (PLC); cd00275
3beta-hydroxysteroid dehydrogenase (3b-HSD)-like, subgroup1, extended (e) SDRs; cd09812
3-beta hydroxysteroid dehydrogenase/isomerase family; pfam01073
short chain dehydrogenase; Provisional
human 17beta-hydroxysteroid dehydrogenase type 2 (type 2 17beta-HSD)-like, classical (c) SDRs; cd09805
M-phase phosphoprotein 6; pfam10175
Cadherin prodomain like; pfam08758
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin prodomain like; pfam08758
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin prodomain like; pfam08758
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin prodomain like; pfam08758
Cadherin prodomain like; pfam08758
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Heat shock factor binding protein 1; pfam06825
Malonyl-CoA decarboxylase (MCD); pfam05292
putative bacillithiol system oxidoreductase, YpdA family; TIGR04018
NADPH-dependent glutamate synthase beta chain and related oxidoreductases [Amino acid transport and metabolism / General function prediction only]; COG0493
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Antibiotic biosynthesis monooxygenase; pfam03992
Transmembrane amino acid transporter protein; cl15776
Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; COG1404
Peptidase S8 family domain in SKI-1-like proteins; cd07479
Domain of unknown function (DUF4350); pfam14258
17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs; cd05356
Short-chain dehydrogenases of various substrate specificities [General function prediction only]; COG0300
ketoreductase/ oxidoreductase
17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs; cd05356
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Adenosine-deaminase (editase) domain; pfam02137
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Adenosine-deaminase (editase) domain; pfam02137
K+ channel tetramerisation domain; pfam02214
Ion transport protein; pfam00520
Ion channel; pfam07885
whey acidic protein-type four-disulfide core domains. Members of the family include whey acidic protein, elafin (elastase-specific inhibitor), caltrin-like protein (a calcium transport inhibitor) and other extracellular proteinase inhibitors. A group of...; cd00199
golgi membrane calcium-translocating P-type ATPase; TIGR01522
Cation transporter/ATPase, N-terminus; pfam00690
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
Cation transporting ATPase, C-terminus; pfam00689
domain in TBC and LysM domain containing proteins; smart00584
Coactosin-like members of the ADF homology domain family; cd11282
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cd02257
SCP_euk: SCP-like extracellular protein domain, as found mainly in eukaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5 from vespid venom. It has been proposed...; cd05380
LCCL domain; smart00603
LCCL domain; smart00603
DHHC palmitoyltransferase; pfam01529
DHHC palmitoyltransferase; pfam01529
Myotubularin protein; pfam12335
The Bin/Amphiphysin/Rvs (BAR) domain of Family with sequence similarity 92 (FAM92); cd07598
Protein of unknown function (DUF3736); pfam12540
Protein of unknown function (DUF3736); pfam12540
Protein of unknown function (DUF3736); pfam12540
Protein of unknown function (DUF3736); pfam12540
Alpha-helical domain of GINS complex protein Psf2 (partner of Sld5 2); cd11712
Mov34/MPN/PAD-1 family: UPF0172 family of unknown function includes neighbor of COX4 (Noc4p); cd08060
Mov34/MPN/PAD-1 family: UPF0172 family of unknown function includes neighbor of COX4 (Noc4p); cd08060
Cytochrome c oxidase subunit IV. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; cd00922
Interferon Regulatory Factor (IRF); also known as tryptophan pentad repeat. The family of IRF transcription factors is important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. The...; cd00103
Interferon-regulatory factor 3; pfam10401
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
5-formyltetrahydrofolate cyclo-ligase family; cl00360
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
5-formyltetrahydrofolate cyclo-ligase family; cl00360
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
5-formyltetrahydrofolate cyclo-ligase family; cl00360
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
5-formyltetrahydrofolate cyclo-ligase family; cl00360
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
5-formyltetrahydrofolate cyclo-ligase family; cl00360
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
F-box-like; pfam12937
Domain of unknown function (DUF3506); pfam12014
Ubiquitin domain of GABA-receptor-associated protein; cd01611
SAM domain of ZCCH14 subfamily; cd09558
zinc finger; smart00343
MORN repeat; cl14787
MORN repeat; pfam02493
MORN repeat; pfam02493
Galactose oxidase, central domain; cl02701
Galactose oxidase, central domain; pfam13415
Galactose oxidase, central domain; pfam13418
Galactose oxidase, central domain; cl02701
Galactose oxidase, central domain; cl02701
Galactose oxidase, central domain; pfam13415
Galactose oxidase, central domain; pfam13418
Galactose oxidase, central domain; cl02701
Galactose oxidase, central domain; cl02701
Galactose oxidase, central domain; pfam13415
Galactose oxidase, central domain; pfam13415
Galactose oxidase, central domain; pfam13418
Galactose oxidase, central domain; cl02701
Galactose oxidase, central domain; cl02701
L-type amino acid transporter; TIGR00911
Carbonic anhydrase alpha, CA isozyme V_like subgroup.  Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; cd03118
The BEN domain is found in diverse animal proteins; smart01025
The BEN domain is found in diverse animal proteins; smart01025
The BEN domain is found in diverse animal proteins; smart01025
The BEN domain is found in diverse animal proteins; smart01025
The BEN domain is found in diverse animal proteins; smart01025
The BEN domain is found in diverse animal proteins; smart01025
The BEN domain is found in diverse animal proteins; smart01025
DNA polymerase III subunits gamma and tau; Validated
transcriptional regulator ICP4; Provisional
transcriptional regulator ICP4; Provisional
Zinc-finger double domain; pfam13465
C2H2-type zinc finger; pfam13912
C2H2-type zinc finger; pfam13912
C2H2-type zinc finger; pfam13912
C2H2-type zinc finger; pfam13912
zinc finger; smart00356
Interleukin-17; pfam06083
Cytochrome Cytochrome b558 alpha-subunit; pfam05038
diphosphomevalonate decarboxylase
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Drought induced 19 protein (Di19); pfam05605
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Drought induced 19 protein (Di19); pfam05605
Drought induced 19 protein (Di19); pfam05605
Protein of unknown function (DUF2392); pfam10288
Protein of unknown function (DUF2392); pfam10288
Protein of unknown function (DUF3595); pfam12166
The middle winged helix fold of replication licensing factor Cdt1 binds geminin to inhibit binding of the MCM complex to origins of replication and DNA; cd08674
The C-terminal fold of replication licensing factor Cdt1 is essential for Cdt1 activity and directly interacts with MCM2-7 helicase; cd08767
Phosphoribosyl transferase (PRT)-type I domain; cd06223
Phosphoribosyl transferase (PRT)-type I domain; cd06223
Sulfatase; pfam00884
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sedlin, N-terminal conserved region; pfam04628
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
NHR1 homology to TAF; pfam07531
NHR2 domain like; pfam08788
ATP synthase B/B' CF(0); cl07975
MYND finger; pfam01753
NHR1 homology to TAF; pfam07531
NHR2 domain like; pfam08788
ATP synthase B/B' CF(0); cl07975
MYND finger; pfam01753
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; COG0318
AMP-binding enzyme; pfam00501
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; COG0318
AMP-binding enzyme; pfam00501
Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; COG0318
AMP-binding enzyme; pfam00501
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin repeat-like domain; cl15786
Cadherin cytoplasmic region; pfam01049
cation transport protein; TIGR00898
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ATP-dependent metalloprotease FtsH; TIGR01241
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Peptidase family M41; pfam01434
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
60S ribosomal protein L13; Provisional
Ribosomal protein L13e; pfam01294
60S ribosomal protein L13; Provisional
Ribosomal protein L13e; pfam01294
60S ribosomal protein L13; Provisional
Ribosomal protein L13e; cl01799
60S ribosomal protein L13; Provisional
Ribosomal protein L13e; cl01799
C2 domain first repeat in Copine; cd04048
C2 domain second repeat in Copine; cd04047
VWA Copine: Copines are phospholipid-binding proteins originally identified in paramecium. They are found in human and orthologues have been found in C. elegans and Arabidopsis Thaliana. None have been found in D. Melanogaster or S. Cereviciae; cd01459
C2 domain first repeat in Copine; cd04048
C2 domain second repeat in Copine; cd04047
VWA Copine: Copines are phospholipid-binding proteins originally identified in paramecium. They are found in human and orthologues have been found in C. elegans and Arabidopsis Thaliana. None have been found in D. Melanogaster or S. Cereviciae; cd01459
renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; cd01301
renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; cd01301
Snf7; cl02305
Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10; cd07845
cyclin-dependent protein kinase; Provisional
Protein Kinases, catalytic domain; cl09925
Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10; cd07845
Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10; cd07845
Vacuolar sorting protein 9 (VPS9) domain; pfam02204
Zinc-finger associated domain (zf-AD); pfam07776
Zinc-finger double domain; pfam13465
Zinc-finger associated domain (zf-AD); pfam07776
Fanconi anaemia group A protein; pfam03511
kinase non-catalytic C-lobe domain; smart00750
Transcriptional repressor TCF25; pfam04910
7 transmembrane receptor (rhodopsin family); pfam00001
tubulin beta chain; Provisional
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02187
Tubulin/FtsZ family, GTPase domain; pfam00091
Tubulin C-terminal domain; pfam03953
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Domain of unknown function (DUF4206); pfam13901
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Domain of unknown function (DUF4206); pfam13901
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Domain of unknown function (DUF4206); pfam13901
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Domain of unknown function (DUF4206); pfam13901
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Domain of unknown function (DUF4206); pfam13901
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Domain of unknown function (DUF4206); pfam13901
Helix-turn-helix domains; cl00088
Tc5 transposase DNA-binding domain; pfam03221
Dysbindin (Dystrobrevin binding protein 1); pfam04440
Dysbindin (Dystrobrevin binding protein 1); pfam04440
Growth-arrest specific micro-tubule binding; pfam13851
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
SSXRD motif; pfam09514
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
C2 domain first repeat present in Rabphilin and Double C2 domain; cd04035
C2 domain second repeat present in Rabphilin and Double C2 domain; cd08384
Rabphilin-3A effector domain N-terminal; pfam02318
Rabphilin-3A effector domain N-terminal; pfam02318
Rabphilin-3A effector domain N-terminal; pfam02318
Rabphilin-3A effector domain N-terminal; pfam02318
glycophorin-binding protein; Provisional
Vps53-like, N-terminal; pfam04100
Vps53-like, N-terminal; pfam04100
TRAM, LAG1 and CLN8 homology domains; smart00724
lactoylglutathione lyase
This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; cd08358
This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; cd06587
rRNA methylases [Translation, ribosomal structure and biogenesis]; COG0566
RNA 2'-O ribose methyltransferase substrate binding; smart00967
SpoU rRNA Methylase family; pfam00588
Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; cl00388
Tryparedoxin (TryX)-like family, TryX and nucleoredoxin (NRX) subfamily; TryX and NRX are thioredoxin (TRX)-like protein disulfide oxidoreductases that alter the redox state of target proteins via the reversible oxidation of an active center CXXC motif; cd03009
PDIb' family, NRX subgroup, redox inactive TRX-like domain b'; composed of vertebrate nucleoredoxins (NRX). NRX is a 400-amino acid nuclear protein with one redox active TRX domain followed by one redox inactive TRX-like domain homologous to the b'...; cd03071
Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; cl00388
Tryparedoxin (TryX)-like family, TryX and nucleoredoxin (NRX) subfamily; TryX and NRX are thioredoxin (TRX)-like protein disulfide oxidoreductases that alter the redox state of target proteins via the reversible oxidation of an active center CXXC motif; cd03009
Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; cl00388
Tim17/Tim22/Tim23/Pmp24 family; pfam02466
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
BCR (breakpoint cluster region)-related pleckstrin homology (PH) domain; cd01228
Pleckstrin homology-like domain; cl00273
C2 domain in the Active BCR (Breakpoint cluster region) Related protein; cd08686
RhoGAP_Bcr: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Bcr (breakpoint cluster region protein)-like proteins. Bcr is a multidomain protein with a variety of enzymatic functions. It contains a RhoGAP and a Rho GEF domain; cd04387
GTPase-activator protein for Rho-like GTPases; smart00324
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
BCR (breakpoint cluster region)-related pleckstrin homology (PH) domain; cd01228
Pleckstrin homology-like domain; cl00273
C2 domain in the Active BCR (Breakpoint cluster region) Related protein; cd08686
RhoGAP_Bcr: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Bcr (breakpoint cluster region protein)-like proteins. Bcr is a multidomain protein with a variety of enzymatic functions. It contains a RhoGAP and a Rho GEF domain; cd04387
GTPase-activator protein for Rho-like GTPases; smart00324
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
BCR (breakpoint cluster region)-related pleckstrin homology (PH) domain; cd01228
Pleckstrin homology-like domain; cl00273
C2 domain in the Active BCR (Breakpoint cluster region) Related protein; cd08686
RhoGAP_Bcr: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Bcr (breakpoint cluster region protein)-like proteins. Bcr is a multidomain protein with a variety of enzymatic functions. It contains a RhoGAP and a Rho GEF domain; cd04387
GTPase-activator protein for Rho-like GTPases; smart00324
C2 domain; cl14603
RhoGAP_Bcr: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Bcr (breakpoint cluster region protein)-like proteins. Bcr is a multidomain protein with a variety of enzymatic functions. It contains a RhoGAP and a Rho GEF domain; cd04387
GTPase-activator protein for Rho-like GTPases; smart00324
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Interferon-induced transmembrane protein; pfam04505
14-3-3 epsilon, an isoform of 14-3-3 protein; cd10020
Src homology 2 domain found in cancer-related signaling adaptor protein CRK; cd09926
N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins; cd11758
C-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins; cd11759
Src homology 2 domain found in cancer-related signaling adaptor protein CRK; cd09926
N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins; cd11758
Myosin. Large ATPases; smart00242
Myosin motor domain, type I myosins. Myosin I generates movement at the leading edge in cell motility, and class I myosins have been implicated in phagocytosis and vesicle transport. Myosin I, an unconventional myosin, does not form dimers. This...; cd01378
Myosin tail; pfam06017
Myosin. Large ATPases; smart00242
Myosin motor domain, type I myosins. Myosin I generates movement at the leading edge in cell motility, and class I myosins have been implicated in phagocytosis and vesicle transport. Myosin I, an unconventional myosin, does not form dimers. This...; cd01378
Myosin tail; pfam06017
Myosin. Large ATPases; smart00242
Myosin motor domain, type I myosins. Myosin I generates movement at the leading edge in cell motility, and class I myosins have been implicated in phagocytosis and vesicle transport. Myosin I, an unconventional myosin, does not form dimers. This...; cd01378
Myosin tail; pfam06017
Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; cl00490
Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; cl00490
Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; cl00490
Lipid-binding SRPBCC domain of mammalian PITPNA, -B, and related proteins (Class I PITPs); cd08888
Major Facilitator Superfamily; pfam07690
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Rab interacting lysosomal protein; pfam11461
U5 snRNP spliceosome subunit [RNA processing and modification]; COG5178
PRO8NT (NUC069), PrP8 N-terminal domain; pfam08082
PROCN (NUC071) domain; pfam08083
RNA recognition motif of the spliceosomal PrP8; pfam10598
U5-snRNA binding site 2 of PrP8; pfam10597
U6-snRNA interacting domain of PrP8; pfam10596
PRP8 domain IV core; pfam12134
Mpr1p, Pad1p N-terminal (MPN) domains without isopeptidase activity found in splicing factor Prp8; cd08056
TLC domain; cl02759
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
BEACH (Beige and Chediak-Higashi) domains, implicated in membrane trafficking,  are present in a family of proteins conserved throughout eukaryotes. This group contains human lysosomal trafficking regulator (LYST), LPS-responsive and beige-like anchor; cd06071
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Serpin (serine protease inhibitor); pfam00079
Alpha2-antiplasmin (alpha2AP) is the primary inhibitor of plasmin, a proteinase that digests fibrin, the main component of blood clots. Alpha2-Antiplasmin forms an inactive 1 : 1 stoichiometric complex with plasmin. It also rapidly crosslinks to fibrin...; cd02053
Alpha2-antiplasmin (alpha2AP) is the primary inhibitor of plasmin, a proteinase that digests fibrin, the main component of blood clots. Alpha2-Antiplasmin forms an inactive 1 : 1 stoichiometric complex with plasmin. It also rapidly crosslinks to fibrin...; cd02053
Pigment epithelium-derived factor (PEDF)_like. PEDF is non-inhibitory member of the Serpin superfamily. It exhibits neurotrophic, neuroprotective and antiangiogenic properties and is widely expressed in the developing and adult nervous systems. This...; cd02052
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
MYND finger; pfam01753
SET domain; pfam00856
replication factor-a protein 1 (rpa1); TIGR00617
RPA1N: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of human RPA1 (also called RPA70). RPA1 is the large subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which appears to be involved in all...; cd04477
RPA1_DBD_A: A subfamily of OB folds corresponding to the second OB fold, the ssDNA-binding domain (DBD)-A, of human RPA1 (also called RPA70). RPA1 is the large subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which...; cd04474
RPA1_DBD_B: A subfamily of OB folds corresponding to the third OB fold, the ssDNA-binding domain (DBD)-B, of human RPA1 (also called RPA70). RPA1 is the large subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which...; cd04475
RPA1_DBD_C: A subfamily of OB folds corresponding to the C-terminal OB fold, the ssDNA-binding domain (DBD)-C, of human RPA1 (also called RPA70). RPA1 is the large subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which...; cd04476
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
diphthamide biosynthesis enzyme Dph1/Dph2 domain; TIGR00322
Putative diphthamide synthesis protein; pfam01866
Serine hydrolase (FSH1); pfam03959
BTB/POZ domain; pfam00651
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
BTB/POZ domain; pfam00651
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Telomerase activating protein Est1; pfam10374
Est1 DNA/RNA binding domain; pfam10373
PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs; cd09885
Est1 DNA/RNA binding domain; pfam10373
PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs; cd09885
Est1 DNA/RNA binding domain; pfam10373
PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs; cd09885
serine racemase
Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; cd01562
AARP2CN (NUC121) domain; smart00785
Protein of unknown function (DUF663); pfam04950
RUN domain; pfam02759
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
RUN domain; pfam02759
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Protein of unknown function (DUF2630); pfam10944
Protein of unknown function (DUF890); pfam05971
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
LisH; pfam08513
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Clustered mitochondria; pfam13236
Translation initiation factor eIF3 subunit 135; pfam12807
Tetratricopeptide repeat; pfam13374
Tetratricopeptide repeat; pfam13424
Rap/ran-GAP; pfam02145
Rap/ran-GAP; pfam02145
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Peptidase M14 Aspartoacylase (ASPA) subfamily; cd06909
Succinylglutamate desuccinylase / Aspartoacylase family; pfam04952
Peptidase M14 Aspartoacylase (ASPA) subfamily; cd06909
Succinylglutamate desuccinylase / Aspartoacylase family; pfam04952
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
transient-receptor-potential calcium channel protein; TIGR00870
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Polycystin cation channel; pfam08016
transient-receptor-potential calcium channel protein; TIGR00870
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Polycystin cation channel; pfam08016
transient-receptor-potential calcium channel protein; TIGR00870
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Polycystin cation channel; pfam08016
transient-receptor-potential calcium channel protein; TIGR00870
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Polycystin cation channel; pfam08016
sedoheptulokinase-like proteins; a subfamily of the FGGY family of carbohydrate kinases; cd07777
Lysosomal Cystine Transporter; TIGR00951
PQ loop repeat; pfam04193
PQ loop repeat; pfam04193
Lysosomal Cystine Transporter; TIGR00951
PQ loop repeat; pfam04193
PQ loop repeat; pfam04193
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Rab5-interacting protein (Rab5ip); pfam07019
Rab5-interacting protein (Rab5ip); pfam07019
cation transporter protein; TIGR00863
cation transporter protein; TIGR00863
cation transporter protein; TIGR00863
cation transporter protein; TIGR00863
Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta...; cd01469
Integrin alpha (beta-propellor repeats); smart00191
Integrin alpha (beta-propellor repeats); smart00191
FG-GAP repeat; cl15299
Integrin alpha; pfam08441
Protein Kinases, catalytic domain; cl09925
Domain of unknown function (DUF3635); pfam12330
Protein of unknown function (DUF2414); pfam10309
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
cation transporter protein; TIGR00863
Cation transporter/ATPase, N-terminus; pfam00690
sarco/endoplasmic reticulum calcium-translocating P-type ATPase; TIGR01116
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
Cation transporting ATPase, C-terminus; pfam00689
Cation transporter/ATPase, N-terminus; pfam00690
sarco/endoplasmic reticulum calcium-translocating P-type ATPase; TIGR01116
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
Cation transporting ATPase, C-terminus; pfam00689
Cation transporter/ATPase, N-terminus; pfam00690
sarco/endoplasmic reticulum calcium-translocating P-type ATPase; TIGR01116
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
Cation transporting ATPase, C-terminus; pfam00689
Cation transporter/ATPase, N-terminus; pfam00690
sarco/endoplasmic reticulum calcium-translocating P-type ATPase; TIGR01116
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
Cation transporting ATPase, C-terminus; pfam00689
Cation transporter/ATPase, N-terminus; pfam00690
sarco/endoplasmic reticulum calcium-translocating P-type ATPase; TIGR01116
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
Cation transporting ATPase, C-terminus; pfam00689
Cation transporter/ATPase, N-terminus; pfam00690
sarco/endoplasmic reticulum calcium-translocating P-type ATPase; TIGR01116
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
Cation transporting ATPase, C-terminus; pfam00689
Cation transporter/ATPase, N-terminus; pfam00690
sarco/endoplasmic reticulum calcium-translocating P-type ATPase; TIGR01116
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
Cation transporting ATPase, C-terminus; pfam00689
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
APC10/DOC1-like domain of uncharacterized Zinc finger ZZ-type and EF-hand domain-containing protein 1 (ZZEF1) and homologs; cd08667
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cl00049
Zinc finger, ZZ type. Zinc finger present in proteins with an EF_hand motif. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding; cd02343
Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have...; cd02249
Cytochrome b5-like Heme/Steroid binding domain; pfam00173
BTB/POZ domain; pfam00651
BTB And C-terminal Kelch; smart00875
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13857
Protein present in Fab1, YOTB, Vac1, and EEA1; smart00064
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
BTB/POZ domain; pfam00651
BTB And C-terminal Kelch; smart00875
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13857
Protein present in Fab1, YOTB, Vac1, and EEA1; smart00064
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Major Facilitator Superfamily; pfam07690
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Major Facilitator Superfamily; pfam07690
DNA polymerase phi; pfam04931
DNA polymerase phi; pfam04931
Gamma-glutamyltransferase [Amino acid transport and metabolism]; cl08040
Gamma-glutamyltransferase [Amino acid transport and metabolism]; cl08040
bZIP transcription factor; cl02576
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and...; cd01753
Lipoxygenase; pfam00305
rRNA processing/ribosome biogenesis; pfam08167
NUC202 domain; pfam08166
NUC202 domain; pfam08166
Arrestin (or S-antigen), N-terminal domain; pfam00339
Arrestin (or S-antigen), C-terminal domain; smart01017
Arrestin (or S-antigen), N-terminal domain; pfam00339
Arrestin (or S-antigen), C-terminal domain; smart01017
Arrestin (or S-antigen), N-terminal domain; pfam00339
Arrestin (or S-antigen), C-terminal domain; smart01017
Arrestin (or S-antigen), N-terminal domain; pfam00339
Arrestin (or S-antigen), C-terminal domain; smart01017
Arrestin (or S-antigen), N-terminal domain; pfam00339
Arrestin (or S-antigen), C-terminal domain; smart01017
Arrestin (or S-antigen), N-terminal domain; pfam00339
Mediator complex protein; pfam10280
MYND finger; pfam01753
MYND finger; pfam01753
MYND finger; pfam01753
L6 membrane protein; pfam05805
Vitelline membrane outer layer protein I (VMO-I) domain, VMO-I is one of the proteins found in the outer layer of the vitelline membrane of poultry eggs; VMO-I, lysozyme, and VMO-II are tightly bound to ovomucin; this complex forms the backbone of the...; cd00220
Vitelline membrane outer layer protein I (VMO-I) domain, VMO-I is one of the proteins found in the outer layer of the vitelline membrane of poultry eggs; VMO-I, lysozyme, and VMO-II are tightly bound to ovomucin; this complex forms the backbone of the...; cl00167
Vitelline membrane outer layer protein I (VMO-I) domain, VMO-I is one of the proteins found in the outer layer of the vitelline membrane of poultry eggs; VMO-I, lysozyme, and VMO-II are tightly bound to ovomucin; this complex forms the backbone of the...; cl00167
Vitelline membrane outer layer protein I (VOMI); pfam03762
Glycolipid transfer protein (GLTP); pfam08718
20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]; COG0638
proteasome beta type-6 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that...; cd03762
20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]; COG0638
proteasome beta type-6 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that...; cd03762
The phosphoinositide binding Phox Homology domain of Phospholipase D2; cd07297
Pleckstrin homology-like domain; cl00273
Catalytic domain, repeat 1, of vertebrate phospholipase D2; cd09843
Catalytic domain, repeat 2, of vertebrate phospholipase D2; cd09845
The phosphoinositide binding Phox Homology domain of Phospholipase D2; cd07297
Pleckstrin homology-like domain; cl00273
Catalytic domain, repeat 1, of vertebrate phospholipase D2; cd09843
Catalytic domain, repeat 2, of vertebrate phospholipase D2; cd09845
Catalytic domain of the Protein Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6; cd06636
Serine/Threonine protein kinases, catalytic domain; smart00220
Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2; smart00036
Catalytic domain of the Protein Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6; cd06636
Serine/Threonine protein kinases, catalytic domain; smart00220
Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2; smart00036
Catalytic domain of the Protein Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6; cd06636
Serine/Threonine protein kinases, catalytic domain; smart00220
Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2; smart00036
Catalytic domain of the Protein Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6; cd06636
Serine/Threonine protein kinases, catalytic domain; smart00220
Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2; smart00036
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
Leucine rich repeat N-terminal domain; smart00013
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine rich repeat C-terminal domain; smart00082
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
PA_C-RZF_ like: Protease-associated (PA) domain C_RZF-like. This group includes various PA domain-containing proteins similar to C-RZF (chicken embryo RING zinc finger) protein. These proteins contain a C3H2C3 RING finger. C-RZF is expressed in embryo...; cd02123
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Profilin binds actin monomers, membrane polyphosphoinositides such as PI(4,5)P2, and poly-L-proline. Profilin can inhibit actin polymerization into F-actin by binding to monomeric actin (G-actin) and terminal F-actin subunits, but - as a regulator of the...; cd00148
enolase
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; cd03313
enolase
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; cd03313
enolase
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; cd03313
R3H domain of a group of metazoan proteins that is related to the sperm-associated antigen 7. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted...; cd02636
CG-1 domains are highly conserved domains of about 130 amino-acid residues; smart01076
IPT/TIG domain; pfam01833
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
CG-1 domains are highly conserved domains of about 130 amino-acid residues; smart01076
IPT/TIG domain; pfam01833
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
CG-1 domain; cl04295
IPT/TIG domain; pfam01833
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
CG-1 domains are highly conserved domains of about 130 amino-acid residues; smart01076
IPT/TIG domain; pfam01833
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
Kinesin motor domain, KIF1_like proteins. KIF1A (Unc104) transports synaptic vesicles to the nerve terminal, KIF1B has been implicated in transport of mitochondria. Both proteins are expressed in neurons. This catalytic (head) domain has ATPase activity...; cd01365
Kinesin motor, catalytic domain. ATPase; smart00129
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
Protein of unknown function (DUF1011); pfam06237
Protein of unknown function (DUF1011); pfam06237
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Ubiquitin carboxyl-terminal hydrolase; pfam00443
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Rabaptin; pfam03528
Rabaptin; pfam03528
Rabaptin-like protein; pfam09311
Rabaptin; pfam03528
Rabaptin; pfam03528
Rabaptin-like protein; pfam09311
Nuclear pore component; pfam10168
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; cl12013
Mitochondrial glycoprotein; pfam02330
HrpA-like helicases [DNA replication, recombination, and repair]; COG1643
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Helicase associated domain (HA2); pfam04408
Oligonucleotide/oligosaccharide-binding (OB)-fold; pfam07717
HrpA-like helicases [DNA replication, recombination, and repair]; COG1643
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Helicase associated domain (HA2); pfam04408
Oligonucleotide/oligosaccharide-binding (OB)-fold; pfam07717
Der1-like family; pfam04511
Mis12 protein; pfam05859
Mis12 protein; pfam05859
Mis12 protein; pfam05859
Mis12 protein; pfam05859
Mis12 protein; pfam05859
Pyrin death domain found in NALP proteins; cd08320
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Function to find; pfam13553
Pyrin death domain found in NALP proteins; cd08320
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Function to find; pfam13553
Caspase activation and recruitment domain found in Human ASC, NALP1, and similar proteins; cd08330
Pyrin death domain found in NALP proteins; cd08320
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Function to find; pfam13553
Caspase activation and recruitment domain found in Human ASC, NALP1, and similar proteins; cd08330
Pyrin death domain found in NALP proteins; cd08320
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Function to find; pfam13553
Caspase activation and recruitment domain found in Human ASC, NALP1, and similar proteins; cd08330
Pyrin death domain found in NALP proteins; cd08320
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Function to find; pfam13553
Caspase activation and recruitment domain found in Human ASC, NALP1, and similar proteins; cd08330
present in yeast cell wall integrity and stress response component proteins; smart00321
present in yeast cell wall integrity and stress response component proteins; smart00321
Sulfotransferase domain; pfam00685
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
FKBP-type peptidyl-prolyl cis-trans isomerase; cl11587
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
FKBP-type peptidyl-prolyl cis-trans isomerase; cl11587
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Protein of unknown function (DUF1466); pfam07326
Protein of unknown function (DUF1466); pfam07326
DDHD domain; pfam02862
LNS2 (Lipin/Ned1/Smp2); pfam08235
This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain and phosphatidylinositol transfer proteins; smart00775
DDHD domain; pfam02862
LNS2 (Lipin/Ned1/Smp2); pfam08235
This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain and phosphatidylinositol transfer proteins; smart00775
The middle winged helix fold of replication licensing factor Cdt1 binds geminin to inhibit binding of the MCM complex to origins of replication and DNA; cl07443
Human TRX-related protein 14 (TRP14)-like family; composed of proteins similar to TRP14, a 14kD cytosolic protein that shows disulfide reductase activity in vitro with a different substrate specificity compared with another human cytosolic protein, TRX1; cd02952
SOH1; pfam05669
Citrate transporter; pfam03600
Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; cd01115
Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; cl15356
Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; COG0471
Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; cd01115
Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; cl15356
PRLI-interacting factor K; Provisional
TRAF-type zinc finger; pfam02176
F-box-like; pfam12937
Tektin family; pfam03148
PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and...; cd01753
Lipoxygenase; pfam00305
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
monocarboxylate transporter 1; TIGR00892
Hepatic lectin, N-terminal domain; pfam03954
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
Hepatic lectin, N-terminal domain; pfam03954
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
Hepatic lectin, N-terminal domain; pfam03954
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
Hepatic lectin, N-terminal domain; pfam03954
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
Hepatic lectin, N-terminal domain; pfam03954
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
Hepatic lectin, N-terminal domain; pfam03954
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
Hepatic lectin, N-terminal domain; pfam03954
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
Hepatic lectin, N-terminal domain; pfam03954
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
Hepatic lectin, N-terminal domain; pfam03954
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
L27 domain; cl02672
Polyubiquitination (PEST) N-terminal domain of MAGUK; pfam10608
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ-associated domain of NMDA receptors; pfam10600
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain of Disks Large homolog 4; cd12030
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
Polyubiquitination (PEST) N-terminal domain of MAGUK; pfam10608
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ-associated domain of NMDA receptors; pfam10600
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain of Disks Large homolog 4; cd12030
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
Very long chain acyl-CoA dehydrogenase; cd01161
Acyl-CoA dehydrogenases [Lipid metabolism]; COG1960
Very long chain acyl-CoA dehydrogenase; cd01161
Acyl-CoA dehydrogenases [Lipid metabolism]; COG1960
Very long chain acyl-CoA dehydrogenase; cd01161
Acyl-CoA dehydrogenases [Lipid metabolism]; COG1960
Very long chain acyl-CoA dehydrogenase; cd01161
Acyl-CoA dehydrogenases [Lipid metabolism]; COG1960
Domain present in Dishevelled and axin; smart00021
Dishevelled specific domain; pfam02377
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins.  Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway...; cd04438
Segment polarity protein dishevelled (Dsh) C terminal; pfam12316
Segment polarity protein dishevelled (Dsh) C terminal; pfam12316
PHD-like zinc-binding domain; pfam13771
PHD zinc finger; smart00249
Ubiquitin domain of GABA-receptor-associated protein; cd01611
FCP1-like phosphatase, phosphatase domain; TIGR02250
Dullard-like phosphatase domain; TIGR02251
FCP1-like phosphatase, phosphatase domain; TIGR02250
Dullard-like phosphatase domain; TIGR02251
Histone acetylation protein 2; pfam10483
Histone acetylation protein 2; pfam10483
Histone acetylation protein 2; pfam10483
Histone acetylation protein 2; pfam10483
PMP-22/EMP/MP20/Claudin family; pfam00822
PMP-22/EMP/MP20/Claudin family; pfam00822
PMP-22/EMP/MP20/Claudin family; cl15797
Sugar (and other) transporter; pfam00083
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458
eukaryotic translation initiation factor 5A; Provisional
S1_eIF5A: Eukaryotic translation Initiation Factor 5A (eIF5A), S1-like RNA-binding domain. eIF5A is an evolutionarily conserved protein found in eukaryotes. eIF5A is the only protein known to have the unusual amino acid hypusine. Hypusine is essential...; cd04468
eukaryotic translation initiation factor 5A; Provisional
S1_eIF5A: Eukaryotic translation Initiation Factor 5A (eIF5A), S1-like RNA-binding domain. eIF5A is an evolutionarily conserved protein found in eukaryotes. eIF5A is the only protein known to have the unusual amino acid hypusine. Hypusine is essential...; cd04468
eukaryotic translation initiation factor 5A; Provisional
S1_eIF5A: Eukaryotic translation Initiation Factor 5A (eIF5A), S1-like RNA-binding domain. eIF5A is an evolutionarily conserved protein found in eukaryotes. eIF5A is the only protein known to have the unusual amino acid hypusine. Hypusine is essential...; cd04468
eukaryotic translation initiation factor 5A; Provisional
S1_eIF5A: Eukaryotic translation Initiation Factor 5A (eIF5A), S1-like RNA-binding domain. eIF5A is an evolutionarily conserved protein found in eukaryotes. eIF5A is the only protein known to have the unusual amino acid hypusine. Hypusine is essential...; cd04468
Topoisomerase II-associated protein PAT1; pfam09770
Neuralized; cl02685
domain in neuralized proteins; smart00588
domain in neuralized proteins; smart00588
Neuralized; cl02685
Neuralized; cl02685
Neuralized; cl02685
Neuralized; cl02685
domain in neuralized proteins; smart00588
domain in neuralized proteins; smart00588
Neuralized; cl02685
Neuralized; cl02685
Neuralized; cl02685
The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with Coiled-coil, ANK repeat and PH domain containing protein 1; cd07639
Centaurin Pleckstrin homology (PH) domain; cd01250
Putative GTPase activating protein for Arf; pfam01412
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13857
BTB/POZ domain; cl02518
SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases; cd09539
Protein tyrosine kinase; pfam07714
Protein Kinases, catalytic domain; cl09925
Src Homology 3 domain superfamily; cl17036
SAM domain of TNK(ACK)-like non-receptor tyrosine-protein kinases; cd09539
Protein tyrosine kinase; pfam07714
Protein Kinases, catalytic domain; cl09925
Src homology 3 domains; smart00326
Scramblase; pfam03803
Scramblase; pfam03803
Protein of unknown function (DUF423); pfam04241
Carboxylesterase family; pfam00135
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Mab-21 protein; pfam03281
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
Cation transporter family protein; TIGR00860
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Neurotransmitter-gated ion-channel transmembrane region; pfam02932
BTB/POZ domain; pfam00651
BTB/POZ domain; pfam00651
EamA-like transporter family; pfam00892
RNA polymerase Rpb1, domain 1; pfam04997
DNA-directed RNA polymerase subunit A'; Validated
RNA polymerase I subunit A N-terminus; smart00663
RNA polymerase Rpb1, domain 3; pfam04983
RNA polymerase Rpb1, domain 4; pfam05000
RNA polymerase Rpb1, domain 6; pfam04992
DNA-directed RNA polymerase subunit A''; Validated
Largest subunit (Rpb1) of Eukaryotic RNA polymerase II (RNAP II), C-terminal domain; cd02584
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cl00147
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cd00184
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cd00184
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cd00184
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cd00184
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cd00184
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cd00184
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cd00184
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cd00184
Ulp1 protease family, C-terminal catalytic domain; pfam02902
helicase 45; Provisional
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
DEAD-like helicases superfamily; smart00487
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Lysosome-associated membrane glycoprotein (Lamp); pfam01299
Lysosome-associated membrane glycoprotein (Lamp); pfam01299
Lysosomal Cystine Transporter; TIGR00951
PQ loop repeat; pfam04193
PQ loop repeat; cl12056
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
Agenet domain; pfam05641
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
Fragile X-related 1 protein C terminal; pfam12235
Acetyltransferases [General function prediction only]; COG0456
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; cd04301
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Sodium / potassium ATPase beta chain; pfam00287
P53 transactivation motif; pfam08563
P53 DNA-binding domain; cd08367
P53 tetramerisation motif; pfam07710
P53 transactivation motif; pfam08563
P53 DNA-binding domain; cd08367
P53 tetramerisation motif; pfam07710
P53 DNA-binding domain; cd08367
P53 tetramerisation motif; pfam07710
P53 DNA-binding domain; cd08367
P53 tetramerisation motif; pfam07710
P53 transactivation motif; pfam08563
P53 DNA-binding domain; cd08367
P53 DNA-binding domain; cd08367
P53 transactivation motif; pfam08563
P53 DNA-binding domain; cd08367
P53 DNA-binding domain; cd08367
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Receptor Binding Domain of Ephrin B; cd10426
Dynein heavy chain, N-terminal region 1; pfam08385
Dynein heavy chain, N-terminal region 2; pfam08393
Hydrolytic ATP binding site of dynein motor region D1; pfam12774
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Microtubule-binding stalk of dynein motor; pfam12777
ATP-binding dynein motor region D5; pfam12781
Dynein heavy chain and region D6 of dynein motor; pfam03028
A domain family that is part of the cupin metalloenzyme superfamily; smart00558
JmjC domain, hydroxylase; pfam02373
LSM domain containing 1; cd06168
Cytochrome b5-like Heme/Steroid binding domain; pfam00173
CHDNT (NUC034) domain; pfam08073
PHD-finger; pfam00628
PHD-finger; pfam00628
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; COG0513
Domain of Unknown Function (DUF1087); pfam06465
Domain of Unknown Function (DUF1086); pfam06461
CHDCT2 (NUC038) domain; pfam08074
CHDNT (NUC034) domain; pfam08073
PHD-finger; pfam00628
PHD-finger; pfam00628
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; COG0513
Domain of Unknown Function (DUF1087); pfam06465
Domain of Unknown Function (DUF1086); pfam06461
CHDCT2 (NUC038) domain; pfam08074
CHDNT (NUC034) domain; pfam08073
PHD-finger; pfam00628
PHD-finger; pfam00628
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; COG0513
Domain of Unknown Function (DUF1087); pfam06465
Domain of Unknown Function (DUF1086); pfam06461
CHDCT2 (NUC038) domain; pfam08074
Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; COG0667
Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; cd06660
Sybindin-like family; pfam04099
Sybindin-like family; pfam04099
chromosome segregation protein SMC, common bacterial type; TIGR02168
Ligand-binding domain of membrane guanylyl cyclases (GC-D, GC-E, and GC-F) that are specifically expressed in sensory tissues; cd06371
Receptor family ligand binding region; pfam01094
Protein tyrosine kinase; pfam07714
Catalytic domain of Protein Kinases; cd00180
Adenylyl- / guanylyl cyclase, catalytic domain; smart00044
Heme NO binding associated; pfam07701
cyclase homology domain; cd07302
PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and...; cd01753
Lipoxygenase; pfam00305
PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and...; cd01753
Lipoxygenase; pfam00305
PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and...; cd01753
Lipoxygenase; pfam00305
PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and...; cd01753
Lipoxygenase; pfam00305
PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and...; cd01753
Lipoxygenase; pfam00305
PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and...; cd01753
Lipoxygenase; pfam00305
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
PAS fold; pfam08447
Period protein 2/3C-terminal region; pfam12114
Synaptobrevin; pfam00957
Uncharacterized conserved protein (DUF2365); pfam10157
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
phosphoribosylformylglycinamidine synthase, single chain form; TIGR01735
PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; cd02203
PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; cd02204
Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; cd01740
homolog to Ran-Binding Protein Mog1p; binds to the small GTPase Ran, which plays an important role in nuclear import. Binding is independent of Ran's nucleotide state (RanGTP/RanGDP); cd00224
homolog to Ran-Binding Protein Mog1p; binds to the small GTPase Ran, which plays an important role in nuclear import. Binding is independent of Ran's nucleotide state (RanGTP/RanGDP); cd00224
homolog to Ran-Binding Protein Mog1p; binds to the small GTPase Ran, which plays an important role in nuclear import. Binding is independent of Ran's nucleotide state (RanGTP/RanGDP); cl00169
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
KRAB (Kruppel-associated box) domain -A box; cd07765
Integrase core domain; pfam00665
KOW motif; cl00354
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
NUDE protein, C-terminal conserved region; pfam04880
NUDE protein, C-terminal conserved region; pfam04880
Myosin N-terminal SH3-like domain; pfam02736
Myosin. Large ATPases; smart00242
Myosin motor domain, type II myosins. Myosin II mediates cortical contraction in cell motility, and is the motor in smooth and skeletal muscle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins...; cd01377
Myosin tail; pfam01576
Myosin N-terminal SH3-like domain; pfam02736
Myosin. Large ATPases; smart00242
Myosin motor domain, type II myosins. Myosin II mediates cortical contraction in cell motility, and is the motor in smooth and skeletal muscle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins...; cd01377
Myosin tail; pfam01576
Myosin N-terminal SH3-like domain; pfam02736
Myosin. Large ATPases; smart00242
Myosin motor domain, type II myosins. Myosin II mediates cortical contraction in cell motility, and is the motor in smooth and skeletal muscle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins...; cd01377
Myosin tail; pfam01576
Domain of unknown function (DUF4200); pfam13863
Domain of unknown function (DUF4200); pfam13863
Cell cycle regulatory protein; pfam11357
MFS_1 like family; pfam12832
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Major Facilitator Superfamily; pfam07690
Phosphoinositide 3-kinase gamma adapter protein p101 subunit; pfam10486
Phosphoinositide 3-kinase gamma adapter protein p101 subunit; pfam10486
Phosphoinositide 3-kinase gamma adapter protein p101 subunit; pfam10486
Phosphoinositide 3-kinase gamma adapter protein p101 subunit; pfam10486
Phosphoinositide 3-kinase gamma adapter protein p101 subunit; pfam10486
Phosphoinositide 3-kinase gamma adapter protein p101 subunit; pfam10486
Phosphoinositide 3-kinase gamma adapter protein p101 subunit; pfam10486
Laminin N-terminal domain (domain VI); smart00136
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
NTR domain, Netrin-1-like subfamily; The C-terminal NTR domain of netrins is also called domain C in the context of C. elegans netrin UNC-6. Netrins are secreted proteins that function as tropic cues in the direction of axon growth and cell migration...; cd03579
Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in...; cd00193
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02674
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02674
11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs; cd05332
short chain dehydrogenase; Provisional
11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs; cd05332
short chain dehydrogenase; Provisional
Hormone receptor domain; pfam02793
7 transmembrane receptor (Secretin family); pfam00002
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Src homology 3 domain of Growth Arrest Specific protein 7; cd11829
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Growth Arrest Specific protein 7; cd07649
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Growth Arrest Specific protein 7; cd07649
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Growth Arrest Specific protein 7; cd07649
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Growth Arrest Specific protein 7; cd07649
Myosin N-terminal SH3-like domain; pfam02736
Myosin. Large ATPases; smart00242
Myosin motor domain, type II myosins. Myosin II mediates cortical contraction in cell motility, and is the motor in smooth and skeletal muscle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins...; cd01377
Myosin tail; pfam01576
Myosin N-terminal SH3-like domain; pfam02736
Myosin. Large ATPases; smart00242
Myosin motor domain, type II myosins. Myosin II mediates cortical contraction in cell motility, and is the motor in smooth and skeletal muscle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins...; cd01377
Myosin tail; pfam01576
Myosin N-terminal SH3-like domain; pfam02736
Myosin. Large ATPases; smart00242
Myosin motor domain, type II myosins. Myosin II mediates cortical contraction in cell motility, and is the motor in smooth and skeletal muscle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins...; cd01377
Myosin tail; pfam01576
Myosin N-terminal SH3-like domain; pfam02736
Myosin. Large ATPases; smart00242
Myosin motor domain, type II myosins. Myosin II mediates cortical contraction in cell motility, and is the motor in smooth and skeletal muscle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins...; cd01377
Myosin tail; pfam01576
Myosin N-terminal SH3-like domain; pfam02736
Myosin. Large ATPases; smart00242
Myosin motor domain, type II myosins. Myosin II mediates cortical contraction in cell motility, and is the motor in smooth and skeletal muscle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins...; cd01377
Myosin tail; pfam01576
Myosin N-terminal SH3-like domain; pfam02736
Myosin. Large ATPases; smart00242
Myosin motor domain, type II myosins. Myosin II mediates cortical contraction in cell motility, and is the motor in smooth and skeletal muscle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins...; cd01377
Myosin tail; pfam01576
Myosin N-terminal SH3-like domain; pfam02736
Myosin. Large ATPases; smart00242
Myosin motor domain, type II myosins. Myosin II mediates cortical contraction in cell motility, and is the motor in smooth and skeletal muscle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins...; cd01377
Myosin tail; pfam01576
Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]
SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; cd02968
Homo sapiens Nbla03831 and related proteins, metallophosphatase domain; cd07396
Calcineurin-like phosphoesterase; pfam00149
Wnt and FGF inhibitory regulator; pfam13908
Wnt and FGF inhibitory regulator; pfam13908
Wnt and FGF inhibitory regulator; pfam13908
Dynein heavy chain, N-terminal region 1; pfam08385
Dynein heavy chain, N-terminal region 2; pfam08393
Hydrolytic ATP binding site of dynein motor region D1; pfam12774
AAA domain (dynein-related subfamily); pfam07728
P-loop containing dynein motor region D3; pfam12775
P-loop containing dynein motor region D4; pfam12780
Microtubule-binding stalk of dynein motor; pfam12777
ATP-binding dynein motor region D5; pfam12781
Dynein heavy chain and region D6 of dynein motor; pfam03028
Dynein heavy chain and region D6 of dynein motor; pfam03028
SCAN oligomerization domain; cd07936
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Catalytic domain of the dual-specificity Protein Kinase, MAP kinase kinase 4; cd06616
Serine/Threonine protein kinases, catalytic domain; smart00220
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2; smart00707
SAP domain; pfam02037
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2; smart00707
SAP domain; pfam02037
Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2; smart00707
SAP domain; pfam02037
BAR domain; smart00721
The Bin/Amphiphysin/Rvs (BAR) domain of RhoGAP interacting with CIP4 homologs protein 2; cd07619
RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when...; cl02570
GTPase-activator protein for Rho-like GTPases; smart00324
Metallo-beta-lactamase superfamily; cl00446
Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; COG1234
Family description; pfam13691
Metallo-beta-lactamase superfamily; cl00446
Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; COG1234
Family description; pfam13691
Metallo-beta-lactamase superfamily; cl00446
Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; COG1234
Sulfotransferase domain; pfam00685
protoheme IX farnesyltransferase; TIGR01473
Sulfotransferase domain; pfam00685
PMP-22/EMP/MP20/Claudin family; pfam00822
PMP-22/EMP/MP20/Claudin family; pfam00822
PMP-22/EMP/MP20/Claudin family; pfam00822
Tektin family; pfam03148
Eukaryotic protein of unknown function (DUF846); pfam05832
Eukaryotic protein of unknown function (DUF846); pfam05832
Eukaryotic protein of unknown function (DUF846); pfam05832
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
associated with SPRY domains; smart00589
Domain in SPla and the RYanodine Receptor; smart00449
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
SWIM zinc finger; cl15408
SWIM zinc finger; cl15408
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
Uncharacterized proteins, LmbE homologs [Function unknown]
Uncharacterized conserved protein [Function unknown]
Ubiquitin; cd01803
Ubiquitin homologues; smart00213
Ubiquitin; cd01803
Ubiquitin homologues; smart00213
Ubiquitin; cd01803
Ubiquitin homologues; smart00213
transient-receptor-potential calcium channel protein; TIGR00870
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
SCAN oligomerization domain; cd07936
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
C2H2-type zinc finger; pfam13912
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Domain of unknown function (DUF3496); pfam12001
TACI, cysteine-rich domain; pfam09305
Outspread Pleckstrin homology (PH) domain; cd01236
Pleckstrin homology (PH) domain; cd00821
Outspread Pleckstrin homology (PH) domain; cd01236
Pleckstrin homology (PH) domain; cd00821
Catalytic domain of vertebrate phospholipase D6 and similar proteins; cd09171
PLD-like domain; pfam13091
Vesicle coat protein involved in Golgi to plasma membrane transport; pfam11704
Vesicle coat protein involved in Golgi to plasma membrane transport; pfam11704
PCI domain; pfam01399
PCI domain; pfam01399
5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C); pfam06941
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
RNA polymerase II transcription mediator complex subunit 9; pfam07544
Ras homolog enriched in striatum (Rhes) and activator of G-protein signaling 1 (Dexras1/AGS1); cd04143
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Phospholipid methyltransferase; pfam04191
Phospholipid methyltransferase; pfam04191
Phospholipid methyltransferase; pfam04191
Phospholipid methyltransferase; pfam04191
Phospholipid methyltransferase; pfam04191
PHD-like zinc-binding domain; pfam13771
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal...; cl02544
GAT domain; pfam03127
VHS domain family, Tom1 subfamily; The VHS domain is an essential part of Tom1 (Target of myb1 - retroviral oncogene) protein. The VHS domain has a superhelical structure similar to the structure of the ARM repeats and is present at the very N-termini of...; cd03565
GAT domain; pfam03127
Leucine rich repeat; pfam13855
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine Rich repeats (2 copies); pfam12799
ATP12 chaperone protein; pfam07542
Vacuolar import and degradation protein; pfam09783
Predicted GTPase [General function prediction only]; COG1163
Developmentally Regulated GTP-binding protein (DRG); cd01896
TGS_DRG_C:   DRG (developmentally regulated GTP-binding protein) represents a family of GTP-binding proteins that includes two members, DRG1 and DRG2. DRG1 and DRG2 have a C-terminal TGS domain (named after the ThrRS, GTPase, and SpoT proteins where it...; cd01666
Myosin. Large ATPases; smart00242
Myosin motor domain, type XV myosins. In vertebrates, myosin XV appears to be expressed in sensory tissue and play a role in hearing. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins are...; cd01387
Domain in Myosin and Kinesin Tails; smart00139
Src Homology 3 domain of Myosin XVa; cd12067
Domain in Myosin and Kinesin Tails; smart00139
Band 4.1 homologues; smart00295
FERM central domain; pfam00373
2OG-Fe(II) oxygenase superfamily; cl15773
LLGL2; pfam08366
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Gelsolin sub-domain 1-like domain found in gelsolin, severin, villin, and related proteins; cd11290
Tandemly repeated domains found in gelsolin, severin, villin, and related proteins; cd11280
Gelsolin sub-domain 3-like domain found in gelsolin, severin, villin, and related proteins; cd11292
Tandemly repeated domains found in gelsolin, severin, villin, and related proteins; cd11280
Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins; cd11288
Gelsolin sub-domain 6-like domain found in gelsolin, severin, villin, and related proteins; cd11291
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Gelsolin sub-domain 1-like domain found in gelsolin, severin, villin, and related proteins; cd11290
Tandemly repeated domains found in gelsolin, severin, villin, and related proteins; cd11280
Gelsolin sub-domain 3-like domain found in gelsolin, severin, villin, and related proteins; cd11292
Tandemly repeated domains found in gelsolin, severin, villin, and related proteins; cd11280
Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins; cd11288
Gelsolin sub-domain 6-like domain found in gelsolin, severin, villin, and related proteins; cd11291
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Gelsolin sub-domain 1-like domain found in gelsolin, severin, villin, and related proteins; cd11290
Tandemly repeated domains found in gelsolin, severin, villin, and related proteins; cd11280
Gelsolin sub-domain 3-like domain found in gelsolin, severin, villin, and related proteins; cd11292
Tandemly repeated domains found in gelsolin, severin, villin, and related proteins; cd11280
Gelsolin sub-domain 5-like domain found in gelsolin, severin, villin, and related proteins; cd11288
Gelsolin sub-domain 6-like domain found in gelsolin, severin, villin, and related proteins; cd11291
Mab-21 protein; pfam03281
Mab-21 protein; pfam03281
Mab-21 protein; pfam03281
Mab-21 protein; pfam03281
Topoisomerase IA [DNA replication, recombination, and repair]; COG0550
TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; cd03362
DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; cd00186
Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; COG0551
Topoisomerase DNA binding C4 zinc finger; pfam01396
GRF zinc finger; pfam06839
GRF zinc finger; pfam06839
serine hydroxymethyltransferase; Provisional
Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; cd00378
serine hydroxymethyltransferase; Provisional
Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; cd00378
Spectrin repeats; smart00150
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
associated with SPRY domains; smart00589
Domain in SPla and the RYanodine Receptor; smart00449
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Eukaryotic protein of unknown function (DUF846); pfam05832
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism / Amino acid transport and metabolism]; COG0462
N-terminal domain of ribose phosphate pyrophosphokinase; pfam13793
Phosphoribosyl transferase (PRT)-type I domain; cd06223
ribose-phosphate pyrophosphokinase; Provisional
N-terminal domain of ribose phosphate pyrophosphokinase; pfam13793
N-terminal domain of ribose phosphate pyrophosphokinase; pfam13793
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism / Amino acid transport and metabolism]; COG0462
Phosphoribosyl transferase (PRT)-type I domain; cd06223
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism / Amino acid transport and metabolism]; COG0462
N-terminal domain of ribose phosphate pyrophosphokinase; pfam13793
Phosphoribosyl transferase (PRT)-type I domain; cd06223
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism / Amino acid transport and metabolism]; COG0462
N-terminal domain of ribose phosphate pyrophosphokinase; pfam13793
Phosphoribosyl transferase (PRT)-type I domain; cd06223
Na(+)/glucose cotransporter SGLT5 and related proteins; solute-binding domain; cd11489
putative transporter; Provisional
Na(+)/glucose cotransporter SGLT5 and related proteins; solute-binding domain; cd11489
putative transporter; Provisional
Solute carrier families 5 and 6-like; solute binding domain; cl00456
putative transporter; Provisional
Na(+)/glucose cotransporter SGLT5 and related proteins; solute-binding domain; cd11489
putative transporter; Provisional
Protein of unknown function (DUF1669); pfam07894
N-terminal phospholipase D-like domain of the uncharacterized protein Family with sequence similarity 83G; cd09187
N-terminal Src homology 3 domain of GRB2-related adaptor protein; cd11948
Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins; cd09941
C-terminal Src homology 3 domain of GRB2-related adaptor protein; cd11951
N-terminal Src homology 3 domain of GRB2-related adaptor protein; cd11948
Src homology 2 (SH2) domain; cl15255
ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated...; cd03571
ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated...; cd03571
Ciliary basal body-associated, B9 protein; pfam07162
Catalytic domain of the Serine/Threonine Kinase, Extracellular signal-Regulated Kinase 5; cd07855
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Serine/Threonine Kinase, Extracellular signal-Regulated Kinase 5; cd07855
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Serine/Threonine Kinase, Extracellular signal-Regulated Kinase 5; cd07855
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Guanylate-binding protein (GBP) family (N-terminal domain); cd01851
Na+-driven multidrug efflux pump [Defense mechanisms]; COG0534
MatE; pfam01554
MatE; pfam01554
aldehyde dehydrogenase family protein; Provisional
Aldehyde dehydrogenase family 3 members A1, A2, and B1 and related proteins; cd07132
aldehyde dehydrogenase family protein; Provisional
Aldehyde dehydrogenase family 3 members A1, A2, and B1 and related proteins; cd07132
Na+-driven multidrug efflux pump [Defense mechanisms]; COG0534
MatE; pfam01554
MatE; pfam01554
Na+-driven multidrug efflux pump [Defense mechanisms]; COG0534
MatE; pfam01554
MatE; pfam01554
Na+-driven multidrug efflux pump [Defense mechanisms]; COG0534
MatE; pfam01554
MatE; pfam01554
aldehyde dehydrogenase family protein; Provisional
Aldehyde dehydrogenase family 3 members A1, A2, and B1 and related proteins; cd07132
aldehyde dehydrogenase family protein; Provisional
Aldehyde dehydrogenase family 3 members A1, A2, and B1 and related proteins; cd07132
aldehyde dehydrogenase family protein; Provisional
Aldehyde dehydrogenase family 3 members A1, A2, and B1 and related proteins; cd07132
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Domain of unknown function (DUF3543); pfam12063
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Domain of unknown function (DUF3543); pfam12063
Regulator of G protein signaling (RGS) domain superfamily; cl02565
Regulator of G protein signaling (RGS) domain 1 found in the A-kinase anchoring protein, D-AKAP2; cd08735
Regulator of G protein signaling (RGS) domain 2 found in the A-kinase anchoring protein, D-AKAP2; cd08721
Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta subunits, the two subunits...; cl09111
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta subunits, the two subunits...; cl09111
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
chromosome segregation protein SMC, common bacterial type; TIGR02168
Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta subunits, the two subunits...; cl09111
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
chromosome segregation protein SMC, common bacterial type; TIGR02168
chromosome segregation protein SMC, common bacterial type; TIGR02168
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Zn-finger in ubiquitin-hydrolases and other protein; pfam02148
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02660
11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs; cd05332
short chain dehydrogenase; Provisional
N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; cl00357
Catalytic domain of the dual-specificity Protein Kinases, MAP kinase kinases 3 and 6; cd06617
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the dual-specificity Protein Kinases, MAP kinase kinases 3 and 6; cd06617
Serine/Threonine protein kinases, catalytic domain; smart00220
Inward rectifier potassium channel N-terminal; pfam08466
Inward rectifier potassium channel; pfam01007
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
SOCS (suppressors of cytokine signaling) box of WSB1/SWiP1-like proteins. This subfamily contains WSB-1 (SOCS-box-containing WD-40 protein), part of an E3 ubiquitin ligase for the thyroid-hormone-activating type 2 iodothyronine deiodinase (D2) and SWiP-1...; cd03746
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
SOCS (suppressors of cytokine signaling) box of WSB1/SWiP1-like proteins. This subfamily contains WSB-1 (SOCS-box-containing WD-40 protein), part of an E3 ubiquitin ligase for the thyroid-hormone-activating type 2 iodothyronine deiodinase (D2) and SWiP-1...; cd03746
SAM like domain present in kinase suppressor RAS 1; pfam13543
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein tyrosine kinase; pfam07714
Catalytic domain of Protein Kinases; cd00180
carbohydrate-binding domain
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
missing in short isoform
carbohydrate-binding domain
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
carbohydrate-binding domain
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
carbohydrate-binding domain
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N...; cd00795
Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; COG0369
Flavodoxin; pfam00258
Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; cl06868
Complex1_LYR-like; pfam13232
Catalytic domain of the Serine/Threonine Kinase, Nemo-Like Kinase; cd07853
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein of unknown function (DUF2781); pfam10914
Protein of unknown function (DUF521); pfam04412
K+ channel tetramerisation domain; pfam02214
Hemimethylated DNA-binding protein YccV like; smart00992
Protein of unknown function (DUF525); cl01119
Endoplasmic reticulum-based factor for assembly of V-ATPase; pfam11712
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Somatomedin B -like domains; smart00201
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
Hemopexin; pfam00045
SAM domain ot SARM1-like proteins, repeat 1; cd09501
Sterile alpha motif; smart00454
SAM domain of SARM1-like, repeat 2; cd09502
Sterile alpha motif; smart00454
Toll - interleukin 1 - resistance; smart00255
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; cl15356
Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; COG0471
Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; cd01115
Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; cd01115
Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; COG0471
Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; cd01115
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
GMP-PDE, delta subunit; pfam05351
GMP-PDE, delta subunit; pfam05351
Phosphatidylinositol-glycan biosynthesis class S protein; pfam10510
Fructose-1,6-bisphosphate aldolase; cd00948
chromosome segregation protein SMC, common bacterial type; TIGR02168
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Mitochondrial protein from FMP27; pfam10344
RNA pol II promoter Fmp27 protein domain; pfam10347
Golgi-body localisation protein domain; pfam10351
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Transcriptional accessory protein [Transcription]; COG2183
Tex-like protein N-terminal domain; pfam09371
Likely ribonuclease with RNase H fold; smart00732
Ribosomal protein S1-like RNA-binding domain; smart00316
N-terminal Src homology 2 (SH2) domain found in Spt6; cd09918
C-terminal Src homology 2 (SH2) domain found in Spt6; cd09928
PLA2_group_III_like: A sub-family of  Phospholipase A2, similar to human group III PLA2. PLA2 is a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. Enzymatically active PLA2 cleaves the sn-2 position...; cd04705
GTPase SAR1 and related small G proteins [General function prediction only]
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
GTPase SAR1 and related small G proteins [General function prediction only]
Rab GTPase families 34 (Rab34) and 36 (Rab36); cd04108
GTPase SAR1 and related small G proteins [General function prediction only]
Rab GTPase families 34 (Rab34) and 36 (Rab36); cd04108
GTPase SAR1 and related small G proteins [General function prediction only]
Rab GTPase families 34 (Rab34) and 36 (Rab36); cd04108
Rab GTPase families 34 (Rab34) and 36 (Rab36); cd04108
GTPase SAR1 and related small G proteins [General function prediction only]
Rab GTPase families 34 (Rab34) and 36 (Rab36); cd04108
GTPase SAR1 and related small G proteins [General function prediction only]
Rab GTPase families 34 (Rab34) and 36 (Rab36); cd04108
GTPase SAR1 and related small G proteins [General function prediction only]
Rab GTPase families 34 (Rab34) and 36 (Rab36); cd04108
Ribosomal protein L23, N-terminal domain; pfam03939
60S ribosomal protein L23a; Provisional
50S ribosomal protein L23P; Provisional
TRAM, LAG1 and CLN8 homology domains; smart00724
TRAM, LAG1 and CLN8 homology domains; smart00724
Catalytic domain of the Protein Serine/Threonine Kinase, Never In Mitosis gene A-related kinase 8; cd08220
Serine/Threonine protein kinases, catalytic domain; smart00220
Regulator of chromosome condensation (RCC1) repeat; pfam13540
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
Regulator of chromosome condensation (RCC1) repeat; pfam00415
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
TRAF-type zinc finger; pfam02176
TRAF-type zinc finger; pfam02176
TRAF-type zinc finger; pfam02176
Tumor Necrosis Factor Receptor (TNFR)-Associated Factor (TRAF) family, TRAF4 subfamily, TRAF domain, C-terminal MATH subdomain; composed of proteins with similarity to human TRAF4, including the Drosophila protein DTRAF1. TRAF molecules serve as adapter...; cd03781
GTPase [General function prediction only]; COG1159
E. coli Ras-like protein (Era) is a multifunctional GTPase; cd04163
Uncharacterized protein conserved in bacteria [Function unknown]
Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; cd03399
The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; cl02525
short chain dehydrogenase; Provisional
retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs; cd05327
PHD-finger; pfam00628
PHD zinc finger; smart00249
PHD-finger; pfam00628
PHD zinc finger; smart00249
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cl00049
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cl00049
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
sarcosine oxidase, monomeric form; TIGR01377
N-methyltryptophan oxidase; Provisional; PRK11259
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Myosin. Large ATPases; smart00242
Myosin motor domain, type XVIII myosins. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins are actin-dependent molecular motors that play important roles in muscle contraction, cell motility, and...; cd01386
Plant protein of unknown function (DUF827); pfam05701
Spc24 subunit of Ndc80; pfam08286
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Myosin. Large ATPases; smart00242
Myosin motor domain, type XVIII myosins. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins are actin-dependent molecular motors that play important roles in muscle contraction, cell motility, and...; cd01386
Plant protein of unknown function (DUF827); pfam05701
Spc24 subunit of Ndc80; pfam08286
N-terminal extension for crystallin, beta A3
N-terminal extension for crystallin, beta A1
Beta/Gamma crystallin; pfam00030
Beta/gamma crystallins; smart00247
Catalytic domain of the Protein Serine/Threonine Kinase, Thousand-and-one amino acids proteins; cd06607
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, Thousand-and-one amino acids proteins; cd06607
Serine/Threonine protein kinases, catalytic domain; smart00220
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]
Protein of unknown function (DUF3105); pfam11303
Putative GTP-ase activating proteins for the small GTPase, ARF; smart00105
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Spa2 homology domain (SHD) of GIT; cl11983
Spa2 homology domain (SHD) of GIT; pfam08518
bZIP transcription factor; cl02576
G protein-coupled receptor kinase-interacting protein 1 C term; pfam12205
Putative GTP-ase activating proteins for the small GTPase, ARF; smart00105
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Spa2 homology domain (SHD) of GIT; cl11983
Spa2 homology domain (SHD) of GIT; pfam08518
bZIP transcription factor; cl02576
G protein-coupled receptor kinase-interacting protein 1 C term; pfam12205
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13857
GPCR-chaperone; pfam11904
Domain of unknown function (DUF1899); pfam08953
coronin; Provisional
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Domain of unknown function (DUF1900); pfam08954
N-terminal domain conserved in slingshot (SSH) phosphatases; cd11652
DEK C terminal domain; pfam08766
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
Domain present in phytochromes and cGMP-specific phosphodiesterases; smart00065
Putative binding domain; pfam13900
Coiled-coil domain-containing protein 55 (DUF2040); pfam09745
Coiled-coil domain-containing protein 55 (DUF2040); pfam09745
Serotonin (5-HT) neurotransmitter transporter, N-terminus; pfam03491
Na(+)- and Cl(-)-dependent serotonin transporter SERT; solute-binding domain; cd11513
Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is...; cd00585
Immunoglobulin domain; cd00096
Peptidase M14 carboxypeptidase subfamily N/E-like; Carboxypeptidase D, domain I subgroup; cd03868
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; cd11308
Peptidase M14 carboxypeptidase subfamily N/E-like; Carboxypeptidase D, domain II subgroup; cd03863
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; cd11308
Peptidase M14 carboxypeptidase subfamily N/E-like; Carboxypeptidase D, domain III subgroup; cd06245
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; cd11308
M14 family of metallocarboxypeptidases and related proteins; cl11393
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; cd11308
Peptidase M14 carboxypeptidase subfamily N/E-like; Carboxypeptidase D, domain II subgroup; cd03863
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; cd11308
Peptidase M14 carboxypeptidase subfamily N/E-like; Carboxypeptidase D, domain III subgroup; cd06245
Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; cd11308
Snare region anchored in the vesicle membrane C-terminus; pfam12352
Snare region anchored in the vesicle membrane C-terminus; pfam12352
Snare region anchored in the vesicle membrane C-terminus; pfam12352
Rab-GTPase-TBC domain; cl02495
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Helix-hairpin-helix motif; pfam12836
Putative GTPase activating protein for Arf; pfam01412
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology-like domain; cl00273
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
SPRY-associated domain; cl02686
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Neurofibromin is the product of the neurofibromatosis type 1 gene (NF1) and shares a region of similarity with catalytic domain of the mammalian p120RasGAP protein and an extended similarity with the Saccharomyces cerevisiae RasGAP proteins Ira1 and Ira2; cd05130
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
Neurofibromin is the product of the neurofibromatosis type 1 gene (NF1) and shares a region of similarity with catalytic domain of the mammalian p120RasGAP protein and an extended similarity with the Saccharomyces cerevisiae RasGAP proteins Ira1 and Ira2; cd05130
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
Leucine rich repeat N-terminal domain; smart00013
Leucine Rich repeats (2 copies); pfam12799
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Ectropic viral integration site 2A protein (EVI2A); pfam05399
Ectropic viral integration site 2A protein (EVI2A); pfam05399
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
FIP domain; pfam09457
U3 small nucleolar RNA-associated protein 6; pfam08640
VEFS-Box of polycomb protein; pfam09733
Leucine rich repeat; pfam13855
GTPase SAR1 and related small G proteins [General function prediction only]
Mitochondrial Rho family 1 (Miro1), N-terminal; cd01893
EF hand associated; pfam08356
EF hand associated; pfam08355
Mitochondrial Rho family 2 (Miro2), C-terminal; cd01892
GTPase SAR1 and related small G proteins [General function prediction only]
Mitochondrial Rho family 1 (Miro1), N-terminal; cd01893
EF hand associated; pfam08356
EF hand associated; pfam08355
Mitochondrial Rho family 2 (Miro2), C-terminal; cd01892
GTPase SAR1 and related small G proteins [General function prediction only]
Mitochondrial Rho family 1 (Miro1), N-terminal; cd01893
EF hand associated; pfam08356
EF hand associated; pfam08355
Mitochondrial Rho family 2 (Miro2), C-terminal; cd01892
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Rhomboid family; pfam01694
26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]; COG5159
PCI domain; pfam01399
26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]; COG5159
PCI domain; pfam01399
Cyclin-dependent kinase 5 activator protein; pfam03261
generated by cleavage of p35 form by calpain
Myosin. Large ATPases; smart00242
Myosin motor domain, type I myosins. Myosin I generates movement at the leading edge in cell motility, and class I myosins have been implicated in phagocytosis and vesicle transport. Myosin I, an unconventional myosin, does not form dimers. This...; cd01378
Myosin tail; pfam06017
Grap2 and cyclin-D-interacting; pfam13324
Grap2 and cyclin-D-interacting; pfam13324
C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have...; cd00119
sodium channel transporter; TIGR00859
sodium channel transporter; TIGR00859
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
TCP-1 (CTT or eukaryotic type II) chaperonin family, zeta subunit. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings. In contrast to bacterial group I chaperonins (GroEL)...; cd03342
TCP-1/cpn60 chaperonin family; pfam00118
TCP-1 (CTT or eukaryotic type II) chaperonin family, zeta subunit. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings. In contrast to bacterial group I chaperonins (GroEL)...; cd03342
TCP-1/cpn60 chaperonin family; pfam00118
TCP-1 (CTT or eukaryotic type II) chaperonin family, zeta subunit. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings. In contrast to bacterial group I chaperonins (GroEL)...; cd03342
TCP-1/cpn60 chaperonin family; pfam00118
U1-like zinc finger; smart00451
Domain of unknown function (DUF4151); pfam13666
Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region; pfam00645
DNA ligase I, ATP-dependent (dnl1); TIGR00574
Adenylation domain of DNA Ligase III; cd07902
The Oligonucleotide/oligosaccharide binding (OB)-fold domain of ATP-dependent DNA ligase III is a DNA-binding module that is part of the catalytic core unit; cd07967
breast cancer carboxy-terminal domain; smart00292
Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region; pfam00645
DNA ligase I, ATP-dependent (dnl1); TIGR00574
Adenylation domain of DNA Ligase III; cd07902
The Oligonucleotide/oligosaccharide binding (OB)-fold domain of ATP-dependent DNA ligase III is a DNA-binding module that is part of the catalytic core unit; cd07967
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Zinc finger, C3HC4 type (RING finger); pfam13920
Zinc finger, C3HC4 type (RING finger); pfam13923
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
AAA domain; pfam13481
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
DNA repair and recombination protein RadA; TIGR02236
Rad51_DMC1_radA,B. This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal proteins radA and radB. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a...; cd01123
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
NLE (NUC135) domain; pfam08154
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
WD domain, G-beta repeat; pfam00400
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Myosin-binding striated muscle assembly central; pfam11701
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Myosin-binding striated muscle assembly central; pfam11701
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Myosin-binding striated muscle assembly central; pfam11701
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
hypothetical protein; Provisional
Divergent AAA domain; pfam04326
Family description; cl15862
hypothetical protein; Provisional
Divergent AAA domain; pfam04326
AAA domain; pfam13173
hypothetical protein; Provisional
Divergent AAA domain; pfam04326
AAA domain; pfam13173
hypothetical protein; Provisional
Divergent AAA domain; pfam04326
AAA domain; pfam13173
hypothetical protein; Provisional
Divergent AAA domain; pfam04326
AAA domain; pfam13173
hypothetical protein; Provisional
Divergent AAA domain; pfam04326
AAA domain; pfam13173
hypothetical protein; Provisional
Divergent AAA domain; pfam04326
hypothetical protein; Provisional
Divergent AAA domain; pfam04326
AAA domain; pfam13173
AAA domain; pfam13401
hypothetical protein; Provisional
Divergent AAA domain; pfam04326
hypothetical protein; Provisional
Divergent AAA domain; pfam04326
Pex2 / Pex12 amino terminal region; pfam04757
Zinc finger, C3HC4 type (RING finger); pfam13923
Ring finger; smart00184
Adaptin N terminal region; pfam01602
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Adaptin C-terminal domain; smart00809
Beta2-adaptin appendage, C-terminal sub-domain; smart01020
Adaptin N terminal region; pfam01602
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Adaptin C-terminal domain; smart00809
Beta2-adaptin appendage, C-terminal sub-domain; smart01020
GTPase SAR1 and related small G proteins [General function prediction only]
Ras-related protein on chromosome 22 (RRP22) family; cd04142
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Growth-Arrest-Specific Protein 2 Domain; pfam02187
Putative peptidoglycan binding domain; pfam01471
Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate...; cd04278
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of...; cd00094
Putative peptidoglycan binding domain; pfam01471
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zinc finger domain; smart00547
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zinc finger domain; smart00547
HEAT repeats; pfam13646
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have...; cd00119
C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have...; cd00119
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
Chemokine_CC:  1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g; cd00272
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
HIT zinc finger; pfam04438
Myosin motor domain. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins are actin-dependent molecular motors that play important roles in muscle contraction, cell motility, and organelle transport; cd00124
Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; cl00286
Myosin. Large ATPases; smart00242
Myosin motor domain. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins are actin-dependent molecular motors that play important roles in muscle contraction, cell motility, and organelle transport; cd00124
Myosin motor domain. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins are actin-dependent molecular motors that play important roles in muscle contraction, cell motility, and organelle transport; cd00124
GWT1; cl02109
Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]
human Mgc4172-like, classical (c) SDRs; cd05343
rRNA methylases [Translation, ribosomal structure and biogenesis]; COG0566
RNA 2'-O ribose methyltransferase substrate binding; pfam08032
SpoU rRNA Methylase family; pfam00588
The first LIM domain of Lhx1 (also known as Lim1) and Lhx5; cd09367
The second LIM domain of Lhx1 (also known as Lim1) and Lhx5; cd09375
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Apoptosis antagonizing transcription factor; pfam13339
Apoptosis-antagonizing transcription factor, C-terminal; pfam08164
Biotin carboxylase [Lipid metabolism]; COG0439
Carbamoyl-phosphate synthase L chain, N-terminal domain; pfam00289
ATP-grasp domain; cl03087
Biotin carboxylase C-terminal domain; smart00878
Biotin carboxyl carrier protein [Lipid metabolism]; COG0511
The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; cd06850
Acetyl-CoA carboxylase, central region; pfam08326
Carboxyl transferase domain; pfam01039
Biotin carboxylase [Lipid metabolism]; COG0439
Carbamoyl-phosphate synthase L chain, N-terminal domain; pfam00289
ATP-grasp domain; cl03087
Biotin carboxylase C-terminal domain; smart00878
Biotin carboxyl carrier protein [Lipid metabolism]; COG0511
The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; cd06850
Acetyl-CoA carboxylase, central region; pfam08326
Carboxyl transferase domain; pfam01039
Biotin carboxylase [Lipid metabolism]; COG0439
Carbamoyl-phosphate synthase L chain, N-terminal domain; pfam00289
ATP-grasp domain; cl03087
Biotin carboxylase C-terminal domain; smart00878
Biotin carboxyl carrier protein [Lipid metabolism]; COG0511
The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; cd06850
Acetyl-CoA carboxylase, central region; pfam08326
Carboxyl transferase domain; pfam01039
Biotin carboxylase [Lipid metabolism]; COG0439
Carbamoyl-phosphate synthase L chain, N-terminal domain; pfam00289
ATP-grasp domain; cl03087
Biotin carboxylase C-terminal domain; smart00878
Biotin carboxyl carrier protein [Lipid metabolism]; COG0511
The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; cd06850
Acetyl-CoA carboxylase, central region; pfam08326
Carboxyl transferase domain; pfam01039
Biotin carboxylase [Lipid metabolism]; COG0439
Carbamoyl-phosphate synthase L chain, N-terminal domain; pfam00289
ATP-grasp domain; cl03087
Biotin carboxylase C-terminal domain; smart00878
Biotin carboxyl carrier protein [Lipid metabolism]; COG0511
The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; cd06850
Acetyl-CoA carboxylase, central region; pfam08326
Carboxyl transferase domain; pfam01039
Zinc finger, ZZ type. Zinc finger present in ADA2, a putative transcriptional adaptor, and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding; cd02335
Histone acetyltransferase complex SAGA/ADA, subunit ADA2 [Chromatin structure and dynamics]
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
SWIRM domain; pfam04433
Zinc finger, ZZ type. Zinc finger present in ADA2, a putative transcriptional adaptor, and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding; cd02335
Histone acetyltransferase complex SAGA/ADA, subunit ADA2 [Chromatin structure and dynamics]
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
SWIRM domain; pfam04433
Zinc finger, ZZ type. Zinc finger present in ADA2, a putative transcriptional adaptor, and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding; cd02335
Histone acetyltransferase complex SAGA/ADA, subunit ADA2 [Chromatin structure and dynamics]
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
ATP-dependent RNA helicase SrmB; Provisional
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Hepatocyte nuclear factor 1 (HNF-1), N terminus; pfam04814
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cl00084
Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus; pfam04812
Hepatocyte nuclear factor 1 (HNF-1), N terminus; pfam04814
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus; pfam04812
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane; smart00978
Calcium-binding EGF-like domain; smart00179
7 transmembrane sweet-taste receptor of 3 GCPR; pfam00003
Src homology 2 (SH2) domain found in  suppressor of cytokine signaling (SOCS) proteins; cd10388
SOCS (suppressors of cytokine signaling) box of SOCS7-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS7 is important in the functioning of neuronal...; cd03741
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Pleckstrin homology-like domain; cl00273
RhoGAP_ARHGAP21: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the...; cd04395
GTPase-activator protein for Rho-like GTPases; smart00324
chromosome segregation protein SMC, primarily archaeal type; TIGR02169
PHD-finger; pfam13831
PHD-zinc-finger like domain; pfam13832
Iron-binding zinc finger CDGSH type; pfam09360
Iron-binding zinc finger CDGSH type; pfam09360
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]; COG0638
proteasome beta type-3 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that...; cd03759
Phosphatidylinositol phosphate kinases (PIPK) catalyze the phosphorylation of phosphatidylinositol phosphate on the fourth or fifth hydroxyl of the inositol ring, to form phosphatidylinositol bisphosphate. CD alignment  includes type II...; cd00139
Phosphatidylinositol phosphate kinases (PIPK) catalyze the phosphorylation of phosphatidylinositol phosphate on the fourth or fifth hydroxyl of the inositol ring, to form phosphatidylinositol bisphosphate. CD alignment  includes type II...; cl02572
N-terminal domain of CBF1 interacting co-repressor CIR; smart01083
Pre-mRNA splicing factor; pfam12542
60S ribosomal protein L23; Provisional
The LIM domain of LIM and SH3 Protein (LASP); cd09447
Nebulin repeat; cl11595
The Nebulin repeat is present also in Las1; smart00227
C-terminal Src Homology 3 domain of LIM and SH3 domain protein 1; cd11934
Nidogen-like; cl02648
Plexin repeat; pfam01437
Arf-like 5 (Arl5) and 8 (Arl8) GTPases; cd04153
GTPase SAR1 and related small G proteins [General function prediction only]
Voltage gated calcium channel subunit beta domain 4Aa N terminal; pfam12052
Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta-1; cd12041
Guanylate kinase; pfam00625
Guanylate kinase homologues; smart00072
Voltage gated calcium channel subunit beta domain 4Aa N terminal; pfam12052
Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta-1; cd12041
Guanylate kinase; pfam00625
Guanylate kinase homologues; smart00072
Voltage gated calcium channel subunit beta domain 4Aa N terminal; pfam12052
Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta-1; cd12041
Guanylate kinase; pfam00625
Guanylate kinase homologues; smart00072
Ribosomal protein L19e, eukaryotic.  L19e is found in the large ribosomal subunit of eukaryotes and archaea. L19e is distinct from the ribosomal subunit L19, which is found in prokaryotes. It consists of two small globular domains connected by an...; cd01417
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
C-terminal Src homology 3 domain of SH3 and cysteine-rich domain-containing protein 2 (Stac2); cd11985
Src Homology 3 domain superfamily; cl17036
F-box-like; pfam12937
Antagonist of mitotic exit network protein 1; cl15308
Antagonist of mitotic exit network protein 1; cl15308
F-box-like; pfam12937
Antagonist of mitotic exit network protein 1; cl15308
Antagonist of mitotic exit network protein 1; cl15308
Mediator of RNA polymerase II transcription subunit 1; pfam10744
Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12; cd07864
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12; cd07864
Serine/Threonine protein kinases, catalytic domain; smart00220
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Neuronal helix-loop-helix transcription factor; pfam12533
Protein phosphatase inhibitor 1/DARPP-32; pfam05395
Protein phosphatase inhibitor 1/DARPP-32; pfam05395
Protein phosphatase inhibitor 1/DARPP-32; pfam05395
Cholesterol-capturing domain; pfam10457
Cholesterol-binding START domain of mammalian STARD3 and related proteins; cd08906
Cholesterol-capturing domain; pfam10457
Cholesterol-binding START domain of mammalian STARD3 and related proteins; cd08906
Cholesterol-capturing domain; pfam10457
Cholesterol-binding START domain of mammalian STARD3 and related proteins; cd08906
Telethonin protein; pfam09470
NNMT/PNMT/TEMT family; pfam01234
Per1-like; pfam04080
Receptor L domain; pfam01030
Furin-like cysteine rich region; pfam00757
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors; cd00064
Receptor L domain; pfam01030
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors; cd00064
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors; cd00064
Transmembrane domain of ErbB2, a Protein Tyrosine Kinase; cd12094
Catalytic domain of the Protein Tyrosine Kinase, HER2; cd05109
Protein tyrosine kinase; pfam07714
Receptor L domain; pfam01030
Furin-like cysteine rich region; pfam00757
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors; cd00064
Receptor L domain; pfam01030
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors; cd00064
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors; cd00064
Transmembrane domain of ErbB2, a Protein Tyrosine Kinase; cd12094
Catalytic domain of the Protein Tyrosine Kinase, HER2; cd05109
Protein tyrosine kinase; pfam07714
Rdx family; pfam10262
RA (RAS-associated like) domain of Grb7; cd01787
Pleckstrin homology-like domain; cl00273
BPS (Between PH and SH2); pfam08947
Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins; cd10413
RA (RAS-associated like) domain of Grb7; cd01787
Pleckstrin homology-like domain; cl00273
BPS (Between PH and SH2); pfam08947
Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins; cd10413
RA (RAS-associated like) domain of Grb7; cd01787
Pleckstrin homology-like domain; cl00273
BPS (Between PH and SH2); pfam08947
Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins; cd10413
RA (RAS-associated like) domain of Grb7; cd01787
Pleckstrin homology-like domain; cl00273
BPS (Between PH and SH2); pfam08947
Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins; cd10413
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zona-pellucida-binding protein (Sp38); pfam07354
Zona-pellucida-binding protein (Sp38); pfam07354
Gasdermin family; pfam04598
Gasdermin family; pfam04598
Gasdermin family; pfam04598
Gasdermin family; pfam04598
ORMDL family; pfam04061
Leucine rich repeat; pfam13855
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Gasdermin family; pfam04598
PCI domain; pfam01399
Proteasome regulatory subunit C-terminal; pfam08375
Interleukin-6/G-CSF/MGF family; pfam00489
Interleukin-6/G-CSF/MGF family; cl02473
Interleukin-6/G-CSF/MGF family; pfam00489
Interleukin-6/G-CSF/MGF family; cl02473
Mediator complex subunit 24 N-terminal; pfam11277
Mediator complex subunit 24 N-terminal; pfam11277
Mediator complex subunit 24 N-terminal; pfam11277
DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers; cd06961
The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors; cd06935
DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers; cd06961
The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors; cd06935
DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers; cd06961
The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors; cd06935
DNA-binding domain of thyroid hormone receptors (TRs) is composed of two C4-type zinc fingers; cd06961
The ligand binding domain of thyroid hormone receptor, a members of a superfamily of nuclear receptors; cd06935
DNA-binding domain of REV-ERB receptor-like is composed of two C4-type zinc fingers; cd07166
The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators; cl11397
CASC3/Barentsz eIF4AIII binding; smart01044
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
WH2 motif; pfam02205
orc1/cdc6 family replication initiation protein
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Winged-helix domain of essential DNA replication protein Cell division control protein (Cdc6), which mediates DNA binding; cd08768
DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers; cd06964
The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily; cd06937
DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers; cd06964
The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily; cd06937
The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily; cd06937
DNA-binding domain of retinoic acid receptor (RAR) is composed of two C4-type zinc fingers; cd06964
The ligand binding domain (LBD) of retinoic acid receptor (RAR), a members of the nuclear receptor superfamily; cd06937
Connexin; pfam00029
Gap junction channel protein cysteine-rich domain; smart01089
DNA topoisomerase 2; Provisional
Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; cd00075
TopoIIA_Trans_ScTopoIIA: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to Saccharomyces cerevisiae Topo IIA.  S. cerevisiae Topo IIA is a homodimer encoded...; cd03481
TOPRIM_TopoIIA: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to Saccharomyces cerevisiae Topoisomerase II. TopoIIA enzymes cut both strands of...; cd03365
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA...; cd00187
DTHCT (NUC029) region; pfam08070
Insulin growth factor-binding protein homologues; smart00121
Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases; cd00191
Src homology 2 (SH2) domain; cl15255
Pleckstrin homology-like domain; cl00273
7 transmembrane receptor (rhodopsin family); pfam00001
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Keratin, high-sulphur matrix protein; pfam04579
Keratin, high-sulphur matrix protein; pfam04579
Keratin, high-sulphur matrix protein; pfam04579
PMG protein; pfam05287
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Intermediate filament protein; pfam00038
Eukaryotic initiation factor 1; cd11566
Gastrin/cholecystokinin family; pfam00918
HAP1 N-terminal conserved region; pfam04849
HAP1 N-terminal conserved region; pfam04849
HAP1 N-terminal conserved region; pfam04849
VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the peripheral V1 complex of V-ATPase, a heteromultimeric enzyme which uses ATP to actively transport protons into organelles and extracellular compartments. The...; cd00256
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the peripheral V1 complex of V-ATPase, a heteromultimeric enzyme which uses ATP to actively transport protons into organelles and extracellular compartments. The...; cd00256
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
FKBP-type peptidyl-prolyl cis-trans isomerase; pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase; pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase; pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase; pfam00254
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Pyrimidine 5'-nucleotidase (UMPH-1); pfam05822
Haloacid Dehalogenase-like Hydrolases; cl11391
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch domain; smart00612
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch domain; smart00612
Kelch domain; smart00612
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch motif; pfam01344
Kelch motif; pfam01344
Kelch domain; smart00612
ATP citrate (pro-S)-lyase
ATP-grasp domain; cl03087
ATP citrate (pro-S)-lyase
CoA binding domain; smart00881
CoA-ligase; cl02894
Citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CCL cleaves citryl-CoA (CiCoA) to acetyl-CoA (AcCoA) and oxaloacetate (OAA); cd06100
ATP citrate (pro-S)-lyase
ATP-grasp domain; cl03087
ATP citrate (pro-S)-lyase
CoA binding domain; smart00881
CoA-ligase; cl02894
Citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CCL cleaves citryl-CoA (CiCoA) to acetyl-CoA (AcCoA) and oxaloacetate (OAA); cd06100
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
AAA domain; pfam13671
AAA domain; pfam13207
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase); pfam05881
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
GTPase SAR1 and related small G proteins [General function prediction only]
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
GTPase SAR1 and related small G proteins [General function prediction only]
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
GTPase SAR1 and related small G proteins [General function prediction only]
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); cd00882
Zinc-finger of C2H2 type; pfam12874
Zinc-finger of C2H2 type; pfam12874
Zinc-finger of C2H2 type; pfam12874
ERCC4-like helicases [DNA replication, recombination, and repair]; COG1111
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
insert domain of MDA5 helicase and similar proteins; cd12090
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
C-terminal domain of RIG-I; pfam11648
PCAF (P300/CBP-associated factor) N-terminal domain; pfam06466
Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription]
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; cd04301
Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long...; cd05509
Alpha crystallin domain (ACD) found in mammalian small heat shock protein (sHsp) HspB9 and similar proteins. sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers...; cd06481
Rab-related GTPase family includes Rab5 and Rab22; regulates early endosome fusion; cd01860
Rab GTPase; Provisional
Rab-related GTPase family includes Rab5 and Rab22; regulates early endosome fusion; cd01860
Rab GTPase; Provisional
Rab-related GTPase family includes Rab5 and Rab22; regulates early endosome fusion; cd01860
Rab GTPase; Provisional
PAS domain; pfam13426
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
Ion transport protein; pfam00520
Ion channel; pfam07885
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
Prepro-orexin; pfam02072
GH3 auxin-responsive promoter; cl04006
GH3 auxin-responsive promoter; cl04006
GH3 auxin-responsive promoter; cl04006
STAT protein, protein interaction domain; pfam02865
STAT protein, all-alpha domain; pfam01017
STAT protein, DNA binding domain; pfam02864
Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5b proteins; cd10420
STAT protein, protein interaction domain; pfam02865
STAT protein, all-alpha domain; pfam01017
STAT protein, DNA binding domain; pfam02864
Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 5a proteins; cd10421
STAT protein, protein interaction domain; smart00964
STAT protein, all-alpha domain; pfam01017
STAT protein, DNA binding domain; pfam02864
Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins; cd10374
STAT protein, protein interaction domain; smart00964
STAT protein, all-alpha domain; pfam01017
STAT protein, DNA binding domain; pfam02864
Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins; cd10374
STAT protein, protein interaction domain; smart00964
STAT protein, all-alpha domain; pfam01017
STAT protein, DNA binding domain; pfam02864
Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins; cd10374
V-type ATPase 116kDa subunit family; pfam01496
V-type ATPase 116kDa subunit family; pfam01496
V-type ATPase 116kDa subunit family; pfam01496
Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain; pfam12971
Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain; pfam05089
Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain; pfam12972
short chain dehydrogenase; Validated
human estrogenic 17beta-hydroxysteroid dehydrogenase type 1 (type 1 17beta-HSD)-like, classical (c) SDRs; cd09806
phosphopantetheine adenylyltransferase domain of eukaryotic and archaeal bifunctional enzymes; cd02164
Cytidylyltransferase; pfam01467
Dephospho-CoA kinase [Coenzyme metabolism]; COG0237
Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; cd02022
phosphopantetheine adenylyltransferase domain of eukaryotic and archaeal bifunctional enzymes; cd02164
Cytidylyltransferase; pfam01467
Dephospho-CoA kinase [Coenzyme metabolism]; COG0237
Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; cd02022
phosphopantetheine adenylyltransferase domain of eukaryotic and archaeal bifunctional enzymes; cd02164
Cytidylyltransferase; pfam01467
Dephospho-CoA kinase [Coenzyme metabolism]; COG0237
Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; cd02022
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Tat binding protein 1(TBP-1)-interacting protein (TBPIP); pfam07106
Helix-turn-helix domains; cl00088
Tat binding protein 1(TBP-1)-interacting protein (TBPIP); pfam07106
Helix-turn-helix domains; cl00088
Tat binding protein 1(TBP-1)-interacting protein (TBPIP); pfam07106
Tat binding protein 1(TBP-1)-interacting protein (TBPIP); pfam07106
Tat binding protein 1(TBP-1)-interacting protein (TBPIP); pfam07106
Reticulon; pfam02453
tubulin gamma chain; Provisional
Gamma-tubulin is a ubiquitous phylogenetically conserved member of tubulin superfamily.  Gamma is a low abundance protein present within the cells in both various types of microtubule-organizing centers and cytoplasmic protein complexes.  Gamma-tubulin...; cd02188
tubulin gamma chain; Provisional
Gamma-tubulin is a ubiquitous phylogenetically conserved member of tubulin superfamily.  Gamma is a low abundance protein present within the cells in both various types of microtubule-organizing centers and cytoplasmic protein complexes.  Gamma-tubulin...; cd02188
Pleckstrin homology (PH) domain; cd00821
MyTH4 domain; cl02480
7 transmembrane receptor (rhodopsin family); pfam00001
Coagulation factor 5/8 C-terminal domain, discoidin domain; smart00231
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; cd00057
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cl00085
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
WD repeat binding protein EZH2; pfam11616
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is...; cd00167
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
Proteins containing SET domain [General function prediction only]
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Receptor activity modifying family; pfam04901
ESCRT-II complex subunit; pfam05871
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Oxidative-stress-responsive kinase 1 C terminal; pfam12202
Coiled-coil domain-containing protein 56; pfam09813
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cl00050
Autophagy protein Apg6; pfam04111
Microtubule-binding stalk of dynein motor; pfam12777
Proteasome activator pa28 alpha subunit; pfam02251
Proteasome activator pa28 beta subunit; pfam02252
Proteasome activator pa28 alpha subunit; pfam02251
Proteasome activator pa28 beta subunit; pfam02252
Proteasome activator pa28 alpha subunit; pfam02251
Proteasome activator pa28 beta subunit; pfam02252
Copper amine oxidase, N2 domain; pfam02727
amine oxidase (copper-containing)
Copper amine oxidase, N3 domain; pfam02728
Copper amine oxidase, enzyme domain; pfam01179
Copper amine oxidase, N2 domain; pfam02727
amine oxidase (copper-containing)
Copper amine oxidase, N3 domain; pfam02728
Copper amine oxidase, enzyme domain; pfam01179
Copper amine oxidase, N2 domain; pfam02727
Copper amine oxidase, N3 domain; pfam02728
Copper amine oxidase, enzyme domain; pfam01179
PAP2_like proteins, glucose-6-phosphatase subfamily. Glucose-6-phosphatase converts glucose-6-phosphate into free glucose and is active in the lumen of the endoplasmic reticulum, where it is bound to the membrane. The generation of free glucose is an...; cd03381
Membrane-associated phospholipid phosphatase [Lipid metabolism]; COG0671
PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; cl00474
p23 binds heat shock protein (Hsp)90 and participates in the folding of a number of Hsp90 clients, including the progesterone receptor. p23 also has a passive chaperoning activity and in addition may participate in prostaglandin synthesis; cd00237
alanine-tRNA ligase
Threonyl and Alanyl tRNA synthetase second additional domain; smart00863
alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins; cl00175
alanine-tRNA ligase
Threonyl and Alanyl tRNA synthetase second additional domain; smart00863
Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain [General function prediction only]
Threonyl and Alanyl tRNA synthetase second additional domain; smart00863
alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins; cl00175
alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins; cl00175
p23 binds heat shock protein (Hsp)90 and participates in the folding of a number of Hsp90 clients, including the progesterone receptor. p23 also has a passive chaperoning activity and in addition may participate in prostaglandin synthesis; cd00237
RUN domain; pfam02759
60S ribosomal protein L27; Provisional
Ribosomal L27e protein family; pfam01777
Interferon-induced 35 kDa protein (IFP 35) N-terminus; pfam07334
Nmi/IFP 35 domain (NID); pfam07292
Nmi/IFP 35 domain (NID); pfam07292
Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; cd08275
NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; COG0604
GTPase SAR1 and related small G proteins [General function prediction only]
Rnd2/Rho7 GTPases; cd04173
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; cd00027
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Serine-rich domain associated with BRCT; pfam12820
Ethylene insensitive 3; pfam04873
Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; cd00027
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Serine-rich domain associated with BRCT; pfam12820
Ethylene insensitive 3; pfam04873
Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; cd00027
Serine-rich domain associated with BRCT; pfam12820
Ethylene insensitive 3; pfam04873
Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; cd00027
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves...; cd06396
Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears...; cd02340
The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves...; cd06396
Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears...; cd02340
The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves...; cd06396
Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears...; cd02340
Protein of unknown function (DUF1356); pfam07092
Arf-like 4 (Arl4) and 7 (Arl7) GTPases; cd04152
Elongation factor Tu GTP binding domain; pfam00009
S1_DHX8_helicase: The  N-terminal S1 domain of human ATP-dependent RNA helicase DHX8, a DEAH (Asp-Glu-Ala-His) box polypeptide.  The DEAH-box RNA helicases are thought to play key roles in pre-mRNA splicing and DHX8 facilitates nuclear export of spliced...; cd05684
DEAD-like helicases superfamily; smart00487
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Helicase associated domain (HA2); pfam04408
Oligonucleotide/oligosaccharide-binding (OB)-fold; pfam07717
PEA3 subfamily ETS-domain transcription factor N terminal domain; pfam04621
Ets-domain; pfam00178
PEA3 subfamily ETS-domain transcription factor N terminal domain; pfam04621
Ets-domain; pfam00178
PEA3 subfamily ETS-domain transcription factor N terminal domain; pfam04621
Ets-domain; pfam00178
PEA3 subfamily ETS-domain transcription factor N terminal domain; pfam04621
Ets-domain; pfam00178
PEA3 subfamily ETS-domain transcription factor N terminal domain; pfam04621
Ets-domain; pfam00178
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Sclerostin (SOST); pfam05463
Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; cd00127
KIAA1430 homologue; pfam13879
L27 domain; pfam02828
domain in receptor targeting proteins Lin-2 and Lin-7; smart00569
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain of Membrane Protein, Palmitoylated 3 (or MAGUK p55 subfamily member 3); cd12039
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
domain in receptor targeting proteins Lin-2 and Lin-7; smart00569
domain in receptor targeting proteins Lin-2 and Lin-7; smart00569
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain of Membrane Protein, Palmitoylated 2 (or MAGUK p55 subfamily member 2); cd12037
Guanylate kinase; pfam00625
Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; cd00071
Pancreatic Hormone domain, a regulator of pancreatic and gastrointestinal functions; neuropeptide Y (NPY)b, peptide YY (PYY), and pancreatic polypetide (PP) are closely related; propeptide is enzymatically cleaved to yield the mature active peptide with...; cd00126
Pancreatic Hormone domain, a regulator of pancreatic and gastrointestinal functions; neuropeptide Y (NPY)b, peptide YY (PYY), and pancreatic polypetide (PP) are closely related; propeptide is enzymatically cleaved to yield the mature active peptide with...; cd00126
AAK_NAGS-Urea: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the urea cycle found in animals. Ureogenic NAGS is a mitochondrial enzyme catalyzing the formation of NAG from acetylcoenzyme A and L-glutamate; NAG is an essential...; cd04236
acetylglutamate kinase; Provisional
DUF619 domain of various N-acetylglutamate Synthases (NAGS) of the urea (U) cycle of humans and fish; cd04265
Like-Sm protein 12, N-terminal domain; cd01735
Anticodon-binding domain; pfam09793
PAP2_like proteins, glucose-6-phosphatase subfamily. Glucose-6-phosphatase converts glucose-6-phosphate into free glucose and is active in the lumen of the endoplasmic reticulum, where it is bound to the membrane. The generation of free glucose is an...; cd03381
Histone deacetylase 5; cd10007
Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; COG0123
Arginase-like and histone-like hydrolases; cl17011
Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; COG0123
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13857
Ankyrin repeats (3 copies); pfam12796
SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins...; cl02533
Ubiquitin homologues; smart00213
Ubiquitin-like domain of UBL; cd01769
Ubiquitin homologues; smart00213
Ubiquitin-like domain of UBL; cd01769
Ubiquitin homologues; smart00213
Ubiquitin-like domain of UBL; cd01769
Sgf11 (transcriptional regulation protein); pfam08209
SCA7, zinc-binding domain; pfam08313
Sgf11 (transcriptional regulation protein); pfam08209
SCA7, zinc-binding domain; pfam08313
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I...; cd00084
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I...; cd00084
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I...; cd00084
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
anion exchange protein; TIGR00834
HCO3- transporter family; pfam00955
RUN domain; pfam02759
RUN domain; pfam02759
RUN domain; pfam02759
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Granulin; smart00277
Granulin; smart00277
Granulin; smart00277
Granulin; smart00277
Granulin; pfam00396
Granulin; smart00277
Granulin; smart00277
Uncharacterized protein family UPF0560; pfam10577
Integrin alpha (beta-propellor repeats); smart00191
Integrin alpha (beta-propellor repeats); smart00191
Family description; pfam13517
Integrin alpha (beta-propellor repeats); smart00191
Family description; pfam13517
Integrin alpha (beta-propellor repeats); smart00191
Integrin alpha; pfam08441
Integrin alpha cytoplasmic region; pfam00357
Zinc-finger double-stranded RNA-binding; pfam12171
Cysteine-rich Wnt-binding domain (CRD) of the frizzled 2 (Fz2) receptor; cd07464
Frizzled/Smoothened family membrane region; pfam01534
DBF zinc finger; pfam07535
DBF zinc finger; pfam07535
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family; cd04269
Disintegrin; pfam00200
ADAM Cysteine-Rich Domain; smart00608
Connexin; pfam00029
Gap junction channel protein cysteine-rich domain; pfam10582
Connexin; pfam00029
Gap junction channel protein cysteine-rich domain; pfam10582
Hypoxia induced protein conserved region; pfam04588
elongation factor 2; Provisional
Snu114p, a spliceosome protein, is a GTPase; cd04167
Loc2 eEF2_C_snRNP, cd01514/C terminal domain:eEF2_C_snRNP: This family includes C-terminal portion of the spliceosomal human 116kD U5 small nuclear ribonucleoprotein (snRNP) protein (U5-116 kD) and, its yeast counterpart Snu114p.  This domain is...; cd04090
EF-2_domain IV_snRNP domain is a part of 116kD U5-specific protein of the U5 small nucleoprotein (snRNP) particle, essential component of the spliceosome. The protein is structurally closely related to the eukaryotic translational elongation factor EF2; cd01683
eEF2_C_snRNP: This family includes a C-terminal portion of the spliceosomal human 116kD U5 small nuclear ribonucleoprotein (snRNP) protein (U5-116 kD) and, its yeast counterpart Snu114p.  This domain is homologous to the C-terminal domain of the...; cd04098
elongation factor 2; Provisional
Snu114p, a spliceosome protein, is a GTPase; cd04167
Loc2 eEF2_C_snRNP, cd01514/C terminal domain:eEF2_C_snRNP: This family includes C-terminal portion of the spliceosomal human 116kD U5 small nuclear ribonucleoprotein (snRNP) protein (U5-116 kD) and, its yeast counterpart Snu114p.  This domain is...; cd04090
EF-2_domain IV_snRNP domain is a part of 116kD U5-specific protein of the U5 small nucleoprotein (snRNP) particle, essential component of the spliceosome. The protein is structurally closely related to the eukaryotic translational elongation factor EF2; cd01683
eEF2_C_snRNP: This family includes a C-terminal portion of the spliceosomal human 116kD U5 small nuclear ribonucleoprotein (snRNP) protein (U5-116 kD) and, its yeast counterpart Snu114p.  This domain is homologous to the C-terminal domain of the...; cd04098
elongation factor 2; Provisional
Snu114p, a spliceosome protein, is a GTPase; cd04167
Loc2 eEF2_C_snRNP, cd01514/C terminal domain:eEF2_C_snRNP: This family includes C-terminal portion of the spliceosomal human 116kD U5 small nuclear ribonucleoprotein (snRNP) protein (U5-116 kD) and, its yeast counterpart Snu114p.  This domain is...; cd04090
EF-2_domain IV_snRNP domain is a part of 116kD U5-specific protein of the U5 small nucleoprotein (snRNP) particle, essential component of the spliceosome. The protein is structurally closely related to the eukaryotic translational elongation factor EF2; cd01683
eEF2_C_snRNP: This family includes a C-terminal portion of the spliceosomal human 116kD U5 small nuclear ribonucleoprotein (snRNP) protein (U5-116 kD) and, its yeast counterpart Snu114p.  This domain is homologous to the C-terminal domain of the...; cd04098
elongation factor 2; Provisional
Snu114p, a spliceosome protein, is a GTPase; cd04167
Loc2 eEF2_C_snRNP, cd01514/C terminal domain:eEF2_C_snRNP: This family includes C-terminal portion of the spliceosomal human 116kD U5 small nuclear ribonucleoprotein (snRNP) protein (U5-116 kD) and, its yeast counterpart Snu114p.  This domain is...; cd04090
EF-2_domain IV_snRNP domain is a part of 116kD U5-specific protein of the U5 small nucleoprotein (snRNP) particle, essential component of the spliceosome. The protein is structurally closely related to the eukaryotic translational elongation factor EF2; cd01683
eEF2_C_snRNP: This family includes a C-terminal portion of the spliceosomal human 116kD U5 small nuclear ribonucleoprotein (snRNP) protein (U5-116 kD) and, its yeast counterpart Snu114p.  This domain is homologous to the C-terminal domain of the...; cd04098
Potential Monad-binding region of RPAP3; pfam13877
Potential Monad-binding region of RPAP3; pfam13877
Potential Monad-binding region of RPAP3; pfam13877
Intermediate filament head (DNA binding) region; pfam04732
Intermediate filament protein; pfam00038
Haloacid Dehalogenase-like Hydrolases; cl11391
Intermediate filament head (DNA binding) region; pfam04732
Intermediate filament protein; pfam00038
Haloacid Dehalogenase-like Hydrolases; cl11391
Intermediate filament head (DNA binding) region; pfam04732
Intermediate filament protein; pfam00038
Haloacid Dehalogenase-like Hydrolases; cl11391
Kinesin motor domain, KIP3-like subgroup. The yeast kinesin KIP3 plays a role in positioning the mitotic spindle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Kinesins are microtubule-dependent...; cd01370
Kinesin motor, catalytic domain. ATPase; smart00129
Kinesin motor domain, KIP3-like subgroup. The yeast kinesin KIP3 plays a role in positioning the mitotic spindle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Kinesins are microtubule-dependent...; cd01370
Kinesin motor, catalytic domain. ATPase; smart00129
C1q domain; pfam00386
dephospho-CoA kinase
Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; cd02022
dephospho-CoA kinase
Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; cd02022
N-myristoyl transferase [Lipid metabolism]; COG5092
Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain; pfam01233
Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain; pfam02799
Phospholipase C (PLC) pleckstrin homology (PH) domain; cd01248
Phosphoinositide phospholipase C
Phosphoinositide-specific phospholipase C, efhand-like; pfam09279
Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta3; cd08630
C2 domain present in Phosphoinositide-specific phospholipases C (PLC); cd00275
Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a...; cd00435
Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a...; cd00435
Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a...; cd00435
Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a...; cd00435
Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a...; cd00435
Diaphanous GTPase-binding Domain; pfam06371
Diaphanous FH3 Domain; pfam06367
Formin Homology 2 Domain; smart00498
Formin Homology 2 Domain; pfam02181
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Domain with 2 conserved Trp (W) residues; smart00456
Pleckstrin homology-like domain; cl00273
RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains; cd04403
GTPase-activator protein for Rho-like GTPases; smart00324
Src Homology 3 domain of Rho GTPase-activating protein 27; cd12069
RUN domain; pfam02759
Pleckstrin homology (PH) domain; cd00821
Pleckstrin homology domain; smart00233
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Domain present in hormone receptors; smart00008
7 transmembrane receptor (Secretin family); pfam00002
Domain present in hormone receptors; smart00008
7 transmembrane receptor (Secretin family); pfam00002
Domain present in hormone receptors; smart00008
7 transmembrane receptor (Secretin family); pfam00002
Hormone receptor domain; cl02422
7 transmembrane receptor (Secretin family); pfam00002
7 transmembrane receptor (Secretin family); pfam00002
PA_hSPPL_like: Protease-associated domain containing human signal peptide peptidase-like (hSPPL)-like. This group contains various PA domain-containing proteins similar to hSPPL2a and 2b. These SPPLs are GxGD aspartic proteases. SPPL2a is sorted to the...; cd02129
Presenilin, signal peptide peptidase, family; smart00730
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Tau and MAP protein, tubulin-binding repeat; pfam00418
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
GTPase SAR1 and related small G proteins [General function prediction only]
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
GTPase SAR1 and related small G proteins [General function prediction only]
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
GTPase SAR1 and related small G proteins [General function prediction only]
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
GTPase SAR1 and related small G proteins [General function prediction only]
Cell division protein 48 (CDC48), N-terminal domain; pfam02359
Cell division protein 48 (CDC48) N-terminal domain; smart01073
Cell division protein 48 (CDC48), domain 2; pfam02933
ATPases associated with a variety of cellular activities; smart00382
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
wnt family; pfam00110
found in Wnt-1; smart00097
wnt family; pfam00110
found in Wnt-1; smart00097
Snare region anchored in the vesicle membrane C-terminus; pfam12352
Snare region anchored in the vesicle membrane C-terminus; pfam12352
Anaphase-promoting complex, cyclosome, subunit 3; pfam12895
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Anaphase-promoting complex, cyclosome, subunit 3; pfam12895
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Integrin, beta chain; pfam00362
Integrin beta tail domain; pfam07965
Integrin beta cytoplasmic domain; pfam08725
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
Peptidase family M1; pfam01433
Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ); cd09601
Domain of unknown function (DUF3358); pfam11838
Karyopherin (importin) beta [Intracellular trafficking and secretion]; COG5215
Importin-beta N-terminal domain; pfam03810
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
TBD domain; pfam12845
T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA...; cd00182
Pleckstrin homology-like domain; cl00273
Oxysterol-binding protein; pfam01237
Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; cd05797
Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; cd05797
Leucine rich repeat; pfam13855
Leucine-rich repeat, SDS22-like subfamily; smart00365
Dipeptidase [Amino acid transport and metabolism]; COG4690
Peptidase family C69; pfam03577
Dipeptidase [Amino acid transport and metabolism]; COG4690
Peptidase family C69; pfam03577
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
pyridoxamine-phosphate oxidase; TIGR00558
Pyridoxamine 5'-phosphate oxidase; pfam01243
Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; pfam10590
Protein of unknown function (DUF773); pfam05600
Clathrin adaptor complex small chain; cl02092
basic region leucin zipper; smart00338
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Chromo Shadow Domain,  found in association with N-terminal chromo (CHRromatin Organization MOdifier) domain; Chromo domains mediate the interaction of the heterochromatin with other heterochromatin proteins, thereby affecting chromatin structure (e.g; cd00034
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Chromo Shadow Domain,  found in association with N-terminal chromo (CHRromatin Organization MOdifier) domain; Chromo domains mediate the interaction of the heterochromatin with other heterochromatin proteins, thereby affecting chromatin structure (e.g; cd00034
The Phox Homology domain, a phosphoinositide binding module; cl02563
The Phox Homology domain, a phosphoinositide binding module; cl02563
Pleckstrin homology (PH) domain; cd00821
Src Homology 3 domain of Src Kinase-Associated Phosphoprotein 1; cd12044
Pleckstrin homology (PH) domain; cd00821
Src Homology 3 domain of Src Kinase-Associated Phosphoprotein 1; cd12044
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Domain of unknown function (DUF4074); pfam13293
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Hox9 activation region; pfam04617
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Hox protein A13 N terminal; pfam12284
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Tubulin-tyrosine ligase family; pfam03133
ATP-grasp domain; cl03087
Calcium binding and coiled-coil domain (CALCOCO1) like; pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; pfam07888
ATP synthase F0 subunit 9; Provisional; MTH00222
ATP synthase F0 subunit 9; Provisional; MTH00222
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
EAP30/Vps36 family; pfam04157
Peptide hormone; pfam00123
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are...; cd02396
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; COG0463
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; cd00761
Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; COG0463
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; cd00761
Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; COG0463
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; cd00761
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors; cd00068
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors; cd00068
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors; cd00068
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors; cd00068
Abl-interactor HHR; pfam07815
Src homology 3 domain of Abl Interactor proteins; cd11826
Abl-interactor HHR; pfam07815
Src homology 3 domain of Abl Interactor proteins; cd11826
Phosphoserine phosphatase [Amino acid transport and metabolism]; COG0560
Putative Phosphatase; pfam06888
Phosphoserine phosphatase [Amino acid transport and metabolism]; COG0560
Putative Phosphatase; pfam06888
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; COG0330
Band_7_prohibitin. A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup group includes proteins similar to prohibitin (a lipid raft-associated integral membrane protein).  Individual proteins of this band 7 domain family may...; cd03401
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Death domain of p75 Neurotophin Receptor; cd08311
Neurexophilin; pfam06312
Speckle-type POZ protein (SPOP) family, MATH domain; composed of proteins with similarity to human SPOP. SPOP was isolated as a novel antigen recognized by serum from a scleroderma patient, whose overexpression in COS cells results in a discrete speckled...; cd03774
BTB/POZ domain; pfam00651
Speckle-type POZ protein (SPOP) family, MATH domain; composed of proteins with similarity to human SPOP. SPOP was isolated as a novel antigen recognized by serum from a scleroderma patient, whose overexpression in COS cells results in a discrete speckled...; cd03774
BTB/POZ domain; pfam00651
Speckle-type POZ protein (SPOP) family, MATH domain; composed of proteins with similarity to human SPOP. SPOP was isolated as a novel antigen recognized by serum from a scleroderma patient, whose overexpression in COS cells results in a discrete speckled...; cd03774
BTB/POZ domain; pfam00651
Speckle-type POZ protein (SPOP) family, MATH domain; composed of proteins with similarity to human SPOP. SPOP was isolated as a novel antigen recognized by serum from a scleroderma patient, whose overexpression in COS cells results in a discrete speckled...; cd03774
BTB/POZ domain; pfam00651
Speckle-type POZ protein (SPOP) family, MATH domain; composed of proteins with similarity to human SPOP. SPOP was isolated as a novel antigen recognized by serum from a scleroderma patient, whose overexpression in COS cells results in a discrete speckled...; cd03774
BTB/POZ domain; pfam00651
Speckle-type POZ protein (SPOP) family, MATH domain; composed of proteins with similarity to human SPOP. SPOP was isolated as a novel antigen recognized by serum from a scleroderma patient, whose overexpression in COS cells results in a discrete speckled...; cd03774
BTB/POZ domain; pfam00651
UAA transporter family; pfam08449
EamA-like transporter family; cl01037
Zinc finger, C2HC type; pfam01530
probable histone acetyltransferase MYST; Provisional
MOZ/SAS family; pfam01853
Zinc finger, C2HC type; pfam01530
probable histone acetyltransferase MYST; Provisional
MOZ/SAS family; pfam01853
Zinc finger, C2HC type; pfam01530
probable histone acetyltransferase MYST; Provisional
MOZ/SAS family; pfam01853
Zinc finger, C2HC type; pfam01530
probable histone acetyltransferase MYST; Provisional
MOZ/SAS family; pfam01853
Zinc finger, C2HC type; pfam01530
probable histone acetyltransferase MYST; Provisional
MOZ/SAS family; pfam01853
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeobox protein distal-less-like N terminal; pfam12413
Homeodomain-containing transcription factor [Transcription]
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Integrin alpha (beta-propellor repeats); smart00191
Integrin alpha (beta-propellor repeats); smart00191
Family description; pfam13517
Integrin alpha (beta-propellor repeats); smart00191
Integrin alpha; pfam08441
Integrin alpha (beta-propellor repeats); smart00191
Integrin alpha (beta-propellor repeats); smart00191
Family description; pfam13517
Integrin alpha (beta-propellor repeats); smart00191
Integrin alpha; pfam08441
Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase; pfam10436
Signal transduction histidine kinase [Signal transduction mechanisms]; COG0642
Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; cd00075
Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase; pfam10436
Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase; pfam10436
Signal transduction histidine kinase [Signal transduction mechanisms]; COG0642
Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; cd00075
Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase; pfam10436
Signal transduction histidine kinase [Signal transduction mechanisms]; COG0642
Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; cd00075
SAM domain of SAM_Neurabin-like subfamily; cd09512
Sterile alpha motif; smart00454
SAM domain of SAM_Neurabin-like subfamily; cd09512
Sterile alpha motif; smart00454
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Sarcoglycan alpha/epsilon; pfam05510
Cadherin repeat-like domain; cl15786
Cadherin repeat-like domain; cl15786
Dystroglycan-type cadherin-like domains; smart00736
von Willebrand factor type C domain; pfam00093
Collagen triple helix repeat (20 copies); pfam01391
Collagen triple helix repeat (20 copies); pfam01391
Fibrillar collagen C-terminal domain; pfam01410
Core-2/I-Branching enzyme; pfam02485
Xylosyltransferase C terminal; pfam12529
Ribosomal L27 protein; cl00359
Leucine rich repeat; pfam13855
AMP-binding domain protein; Validated
AMP-binding enzyme; pfam00501
Domain of unknown function (DUF4009); pfam13193
Leucine rich repeat N-terminal domain; pfam01462
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
coproporphyrinogen III oxidase; Provisional
Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; cd01335
ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated...; cd03571
Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]
TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; cd02955
Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]
TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; cd02955
Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]
TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; cd02955
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
multi drug resistance-associated protein (MRP); TIGR00957
ABC transporter transmembrane region; pfam00664
Domain 1 of the ABC subfamily C.  This family is also known as MRP (mulrtidrug resisitance-associated protein).  Some of the MRP members have five additional transmembrane segments in their N-terminas, but the function of these additional...; cd03250
ABC transporter transmembrane region; pfam00664
Domain 2 of the ABC subfamily C.  This family is also known as MRP (mulrtidrug resisitance-associated protein).  Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional...; cd03244
ABC transporter transmembrane region; pfam00664
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13857
U1 snRNP component, mediates U1 snRNP association with cap-binding complex [RNA processing and modification]; COG5200
U1 snRNP component, mediates U1 snRNP association with cap-binding complex [RNA processing and modification]; COG5200
WAP-type (Whey Acidic Protein) 'four-disulfide core'; pfam00095
Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cd00104
Immunoglobulin I-set domain; pfam07679
Subgroup of the immunoglobulin (Ig) superfamily; cd05765
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
NTR domain, WFIKKN subfamily; WFIKKN proteins contain a C-terminal NTR domain and are putative secreted proteins which may be multivalent protease inhibitors that act on serine proteases as well as metalloproteases. Human WFIKKN and a related protein...; cd03575
tob/btg1 family; smart00099
tob/btg1 family; smart00099
JNK_SAPK-associated protein-1; pfam09744
JNK_SAPK-associated protein-1; pfam09744
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; cl12013
JNK_SAPK-associated protein-1; pfam09744
Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; cd04413
Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; cd04413
Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; cd04413
Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; cd04413
Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; cd04413
Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; cd04413
Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; cd04413
Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; cd04413
Nucleoside diphosphate kinase; pfam00334
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Carbonic anhydrase [Inorganic ion transport and metabolism]; COG3338
Carbonic anhydrase alpha related protein: groups X, XI and related proteins. This subgroup contains carbonic anhydrase related proteins (CARPs) X and XI, which have been implicated in various biological processes of the central nervous system. CARPs are...; cd03121
Carbonic anhydrase [Inorganic ion transport and metabolism]; COG3338
Carbonic anhydrase alpha related protein: groups X, XI and related proteins. This subgroup contains carbonic anhydrase related proteins (CARPs) X and XI, which have been implicated in various biological processes of the central nervous system. CARPs are...; cd03121
Carbonic anhydrase [Inorganic ion transport and metabolism]; COG3338
Carbonic anhydrase alpha related protein: groups X, XI and related proteins. This subgroup contains carbonic anhydrase related proteins (CARPs) X and XI, which have been implicated in various biological processes of the central nervous system. CARPs are...; cd03121
Kinesin motor domain, KIF2-like group. KIF2 is a protein expressed in neurons, which has been associated with axonal transport and neuron development; alternative splice forms have been implicated in lysosomal translocation. This catalytic (head) domain...; cd01367
Kinesin motor, catalytic domain. ATPase; smart00129
VHS domain family, Tom1 subfamily; The VHS domain is an essential part of Tom1 (Target of myb1 - retroviral oncogene) protein. The VHS domain has a superhelical structure similar to the structure of the ARM repeats and is present at the very N-termini of...; cd03565
GAT domain; pfam03127
Cytochrome c oxidase assembly protein CtaG/Cox11; cl01240
Cytochrome c oxidase assembly protein CtaG/Cox11; cl01240
cytochrome c oxidase assembly protein-like; Provisional
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Basic region leucine zipper; pfam07716
channel protein, hemolysin III family; TIGR01065
Lipid-binding START domain of mammalian STARD2 and related proteins; cd08910
START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; cl14643
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Translation initiation factor eIF3 subunit 135; pfam12807
Noggin; pfam05806
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Diacylglycerol kinase catalytic domain (presumed); smart00046
Diacylglycerol kinase accessory domain (presumed); smart00045
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
ATP synthase B/B' CF(0); cl07975
associated with SPRY domains; smart00589
Domain in SPla and the RYanodine Receptor; smart00449
Serine carboxypeptidase; pfam00450
tethering region: binding RII subunits of protein kinase A
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
Tudor domain; pfam00567
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
Tudor domain; pfam00567
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
Tudor domain; pfam00567
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cd04508
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
polyadenylate binding protein, human types 1, 2, 3, 4 family; TIGR01628
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Mitochondrial ribosomal protein S25; pfam13741
Mitochondrial ribosomal protein S23; pfam10484
Domain that may be involved in binding ubiquitin-conjugating enzymes (UBCs); smart00546
Zinc-finger double domain; pfam13465
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
dynein light chain; Provisional
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Animal heme peroxidases and related proteins; cl14561
Myeloperoxidases, eosinophil peroxidases, and lactoperoxidases; cd09824
Ciliary basal body-associated, B9 protein; pfam07162
Ciliary basal body-associated, B9 protein; pfam07162
Animal heme peroxidases and related proteins; cl14561
Animal heme peroxidases and related proteins; cl14561
Myeloperoxidases, eosinophil peroxidases, and lactoperoxidases; cd09824
Animal heme peroxidases and related proteins; cl14561
Animal heme peroxidases and related proteins; cl14561
Myeloperoxidases, eosinophil peroxidases, and lactoperoxidases; cd09824
Animal heme peroxidases and related proteins; cl14561
Myeloperoxidases, eosinophil peroxidases, and lactoperoxidases; cd09824
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; pfam10473
Domain of unknown function (DUF4201); pfam13870
First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins; cd12014
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Second Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins; cd12012
Third Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins; cd12013
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; pfam10473
Domain of unknown function (DUF4201); pfam13870
First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins; cd12014
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Second Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins; cd12012
Third Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins; cd12013
Leucine-rich repeats of kinetochore protein Cenp-F/LEK1; pfam10473
Domain of unknown function (DUF4201); pfam13870
First Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins; cd12014
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Second Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins; cd12012
Third Src homology 3 domain of Rab3-interacting molecules (RIMs) binding proteins; cd12013
Transcription elongation factor Spt4; cd07973
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
HSF-type DNA-binding; pfam00447
Myotubularin-related; pfam06602
Myotubularin Y_phosphatase-like; pfam13849
Protein present in Fab1, YOTB, Vac1, and EEA1; smart00064
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Septin; pfam00735
CDC/Septin GTPase family; cd01850
Septin; pfam00735
CDC/Septin GTPase family; cd01850
Septin; pfam00735
CDC/Septin GTPase family; cd01850
Septin; pfam00735
CDC/Septin GTPase family; cd01850
Septin; pfam00735
CDC/Septin GTPase family; cd01850
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Protein Kinases, catalytic domain; cl09925
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Protein Kinases, catalytic domain; cl09925
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Protein Kinases, catalytic domain; cl09925
DNA repair and recombination protein RadA; Validated; PRK04301
Rad51_DMC1_radA,B. This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal proteins radA and radB. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a...; cd01123
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; cd00143
Protein phosphatase 2C; pfam00481
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins; cd03773
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
B-Box C-terminal domain; smart00502
Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins; cd03773
Uncharacterized conserved protein (DUF2146); pfam10220
Glycerophosphodiester phosphodiesterase domain of mammalian glycerophosphodiester phosphodiesterase GDE4 and similar proteins; cd08612
Glycerophosphodiester phosphodiesterase domain of mammalian glycerophosphodiester phosphodiesterase GDE4 and similar proteins; cd08612
Glycerophosphoryl diester phosphodiesterase family; pfam03009
Glycerophosphodiester phosphodiesterase domain of mammalian glycerophosphodiester phosphodiesterase GDE4 and similar proteins; cd08612
Yippee putative zinc-binding protein; pfam03226
DEAD-like helicases superfamily; smart00487
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Helicase associated domain (HA2); pfam04408
Oligonucleotide/oligosaccharide-binding (OB)-fold; pfam07717
HrpA-like helicases [DNA replication, recombination, and repair]; COG1643
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Helicase associated domain (HA2); pfam04408
Oligonucleotide/oligosaccharide-binding (OB)-fold; pfam07717
Clathrin propeller repeat; pfam01394
Clathrin propeller repeat; pfam01394
Clathrin propeller repeat; pfam01394
Clathrin, heavy-chain linker; pfam09268
Clathrin-H-link; pfam13838
Clathrin heavy chain repeat homology; smart00299
Clathrin heavy chain repeat homology; smart00299
Clathrin heavy chain repeat homology; smart00299
Clathrin heavy chain repeat homology; smart00299
Clathrin heavy chain repeat homology; smart00299
Clathrin heavy chain repeat homology; smart00299
Region in Clathrin and VPS; pfam00637
Peptidyl-tRNA hydrolase PTH2; pfam01981
Peptidyl-tRNA hydrolase, type 2 (PTH2). Peptidyl-tRNA hydrolase (PTH) activity releases tRNA from the premature translation termination product peptidyl-tRNA, therefore allowing the tRNA and peptide to be reused in protein synthesis. PTH2 is present in...; cd02430
SNARE associated Golgi protein; pfam09335
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02189
Tubulin/FtsZ family, GTPase domain; pfam00091
Tubulin/FtsZ: Family includes tubulin alpha-, beta-, gamma-, delta-, and epsilon-tubulins as well as FtsZ, all of which are involved in polymer formation. Tubulin is the major component of microtubules, but also exists as a heterodimer and as a curved...; cl10017
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02189
Tubulin/FtsZ family, GTPase domain; pfam00091
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02189
Tubulin/FtsZ family, GTPase domain; pfam00091
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02189
Tubulin/FtsZ family, GTPase domain; pfam00091
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02189
Tubulin/FtsZ family, GTPase domain; pfam00091
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02189
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, 70 kDa ribosomal protein S6 kinase; cd05584
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Domain of unknown function (DUF4042); pfam13251
HEAT-like repeat; pfam13513
HEAT repeats; pfam13646
Carbonic anhydrase alpha, CA_IV, CA_XV, like isozymes. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; cd03117
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
DUSP domain; pfam06337
DUSP domain; pfam06337
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; cl02553
Ubiquitin carboxyl-terminal hydrolase; pfam00443
Domain of unknown function (DUF4208); pfam13907
Tetratricopeptide repeat; pfam13424
Protein phosphatase 2C; pfam00481
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; cd00143
Breast carcinoma amplified sequence 3; pfam12490
Breast carcinoma amplified sequence 3; pfam12490
T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA...; cd00182
T-box transcription factor; pfam12598
T-box DNA binding domain of the T-box family of transcriptional regulators. The T-box family is an ancient group that appears to play a critical role in development in all animal species. These genes were uncovered on the basis of similarity to the DNA...; cd00182
NAC domain; pfam01849
DNA repair helicase (rad3); TIGR00604
DEAD_2; pfam06733
Helicase C-terminal domain; pfam13307
Mediator complex subunit 13 N-terminal; pfam11597
Mediator complex subunit 13 C-terminal; pfam06333
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13833
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13833
Methyltransferase domain; pfam13847
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; cd00161
Ricin-type beta-trefoil; smart00458
Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and...; cd00062
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cd00037
The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins; smart00744
The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins; smart00744
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Vertebrate cytochrome b(561), CYB561 gene product; cd08763
Vertebrate cytochrome b(561), CYB561 gene product; cd08763
Vertebrate cytochrome b(561), CYB561 gene product; cd08763
Angiotensin-converting enzyme; pfam01401
Peptidase family M2 Angiotensin converting enzyme (ACE); cd06461
Angiotensin-converting enzyme; pfam01401
Peptidase family M2 Angiotensin converting enzyme (ACE); cd06461
Angiotensin-converting enzyme; pfam01401
Peptidase family M2 Angiotensin converting enzyme (ACE); cd06461
Angiotensin-converting enzyme; pfam01401
Peptidase family M2 Angiotensin converting enzyme (ACE); cd06461
PAS domain; pfam13426
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
Voltage-dependent potassium channel; Provisional
Ion channel; pfam07885
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
PAS domain; pfam13426
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; cd00130
Voltage-dependent potassium channel; Provisional
Ion channel; pfam07885
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Transcriptional regulator; pfam01709
The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3)...; cd06405
Catalytic domain of the Protein Serine/Threonine Kinase, MAP/ERK kinase kinase 3; cd06651
Serine/Threonine protein kinases, catalytic domain; smart00220
The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3)...; cd06405
Catalytic domain of the Protein Serine/Threonine Kinase, MAP/ERK kinase kinase 3; cd06651
Serine/Threonine protein kinases, catalytic domain; smart00220
a LIM domain subfamily on a group of proteins with unknown function; cd09486
Serine/Threonine protein kinases, catalytic domain; smart00220
Pseudokinase domain of STE20-related kinase adapter protein alpha; cd08227
Serine/Threonine protein kinases, catalytic domain; smart00220
Pseudokinase domain of STE20-related kinase adapter protein alpha; cd08227
Serine/Threonine protein kinases, catalytic domain; smart00220
Pseudokinase domain of STE20-related kinase adapter protein alpha; cd08227
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Serine/Threonine protein kinases, catalytic domain; smart00220
Pseudokinase domain of STE20-related kinase adapter protein alpha; cd08227
Protein of unknown function (DUF1682); pfam07946
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
DEAD-like helicases superfamily; smart00487
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
DEAD-like helicases superfamily; smart00487
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
23S rRNA methylase [Translation, ribosomal structure and biogenesis]; COG0293
FtsJ-like methyltransferase; pfam01728
Domain of unknown function (DUF3381); pfam11861
Spb1 C-terminal domain; pfam07780
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones]; COG1222
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones]; COG1222
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
SWIB-domain-containing proteins implicated in chromatin remodeling [Chromatin structure and dynamics]
SWIB/MDM2 domain; pfam02201
Somatotropin/prolactin hormone family; cl07831
Somatotropin/prolactin hormone family; cl07831
Somatotropin or growth hormone (GH), placental lactogen, and related pituitary gland hormones; cd10285
Somatotropin/prolactin hormone family; cl07831
Somatotropin/prolactin hormone family; cl07831
Somatotropin or growth hormone (GH), placental lactogen, and related pituitary gland hormones; cd10285
Somatotropin or growth hormone (GH), placental lactogen, and related pituitary gland hormones; cd10285
Somatotropin/prolactin hormone family; cl07831
Somatotropin or growth hormone (GH), placental lactogen, and related pituitary gland hormones; cd10285
Somatotropin/prolactin hormone family; cl07831
Somatotropin/prolactin hormone family; cl07831
Somatotropin or growth hormone (GH), placental lactogen, and related pituitary gland hormones; cd10285
Somatotropin/prolactin hormone family; cl07831
Somatotropin/prolactin hormone family; cl07831
Somatotropin/prolactin hormone family; cl07831
Somatotropin/prolactin hormone family; cl07831
Somatotropin or growth hormone (GH), placental lactogen, and related pituitary gland hormones; cd10285
Somatotropin or growth hormone (GH), placental lactogen, and related pituitary gland hormones; cd10285
Immunoreceptor tyrosine-based activation motif; smart00077
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Sodium ion transport-associated; pfam06512
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Intercellular adhesion molecule (ICAM), N-terminal domain; pfam03921
Second immunoglobulin (Ig)-like domain of intercellular cell adhesion molecule-1 (ICAM-1, CD54) and similar proteins; cd05755
Intercellular adhesion molecule (ICAM), N-terminal domain; pfam03921
Second immunoglobulin (Ig)-like domain of intercellular cell adhesion molecule-1 (ICAM-1, CD54) and similar proteins; cd05755
Intercellular adhesion molecule (ICAM), N-terminal domain; pfam03921
Second immunoglobulin (Ig)-like domain of intercellular cell adhesion molecule-1 (ICAM-1, CD54) and similar proteins; cd05755
Intercellular adhesion molecule (ICAM), N-terminal domain; pfam03921
Second immunoglobulin (Ig)-like domain of intercellular cell adhesion molecule-1 (ICAM-1, CD54) and similar proteins; cd05755
Intercellular adhesion molecule (ICAM), N-terminal domain; pfam03921
Second immunoglobulin (Ig)-like domain of intercellular cell adhesion molecule-1 (ICAM-1, CD54) and similar proteins; cd05755
PQQ-like domain; pfam13360
The Luminal domain, a dimerization domain, of the Serine/Threonine protein kinase, Inositol-requiring protein 1; cd09769
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
RNase domain (also known as the kinase extension nuclease domain) of Ire1; cd10422
Putative integral membrane protein conserved region (DUF2404); pfam10296
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Immunoglobulin domain; pfam13895
Immunoglobulin like; smart00410
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13927
Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3'...; cd00774
C-terminal domain of mitochondrial DNA polymerase gamma B subunit, which is required for processivity. Polymerase gamma replicates and repairs mitochondrial DNA. The c-terminal domain of its B subunit is strikingly similar to the anticodon-binding domain...; cd02426
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
DEAD-like helicases superfamily; smart00487
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
P68HR (NUC004) repeat; pfam08061
P68HR (NUC004) repeat; pfam08061
chromosome segregation protein SMC, common bacterial type; TIGR02168
C2 domain present in Smad ubiquitination-related factor (Smurf)-like proteins; cd08382
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
G protein alpha subunit; smart00275
Alpha subunit of G proteins (guanine nucleotide binding); cd00066
DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain; cd04450
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors; cd00068
Regulator of G protein signaling (RGS) domain found in the RGS9 protein; cd08739
DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain; cd04450
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors; cd00068
Regulator of G protein signaling (RGS) domain found in the RGS9 protein; cd08739
DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain; cd04450
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors; cd00068
Regulator of G protein signaling (RGS) domain found in the RGS9 protein; cd08739
Tankyrase binding N-terminal segment of axin; cd11582
Regulator of G protein signaling (RGS) domain found in the Axin protein; cd08707
Axin beta-catenin binding domain; pfam08833
DIX domain; pfam00778
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
conserved hypothetical protein YmdA/YtgF; TIGR03319
chromosome segregation protein SMC, common bacterial type; TIGR02168
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
conserved hypothetical protein YmdA/YtgF; TIGR03319
chromosome segregation protein SMC, common bacterial type; TIGR02168
phosphodiesterase; Provisional
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Beta-2-glycoprotein-1 fifth domain; pfam09014
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
C2 domain in Protein Kinase C (PKC) alpha and gamma; cd04026
Catalytic domain of the Protein Serine/Threonine Kinase, Classical Protein Kinase C; cd05587
Serine/Threonine protein kinases, catalytic domain; smart00220
PMP-22/EMP/MP20/Claudin tight junction; pfam13903
PMP-22/EMP/MP20/Claudin family; cl15797
PMP-22/EMP/MP20/Claudin tight junction; pfam13903
Zinc finger C-x8-C-x5-C-x3-H type (and similar); pfam00642
AAA domain; pfam13086
AAA domain; pfam13087
PCI domain; cl02111
PCI domain; cl02111
Lipid-binding SRPBCC domain of mammalian PITPNC1,and related proteins (Class IIB PITPs); cd08890
Lipid-binding SRPBCC domain of mammalian PITPNC1,and related proteins (Class IIB PITPs); cd08890
NUC205 domain; pfam08168
DDT domain; pfam02791
PHD-finger; pfam00628
PHD zinc finger; smart00249
Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long...; cd05509
DDT domain; pfam02791
PHD-finger; pfam00628
PHD zinc finger; smart00249
Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long...; cd05509
NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the...; cl02512
Importin beta binding domain; pfam01749
Karyopherin (importin) alpha [Intracellular trafficking and secretion]; COG5064
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Peptidase family M54, also called archaemetzincins or archaelysins; cd11375
Peptidase family M54, also called archaemetzincins or archaelysins; cd11375
Peptidase family M54, also called archaemetzincins or archaelysins; cd11375
Peptidase family M54, also called archaemetzincins or archaelysins; cd11375
Peptidase family M54, also called archaemetzincins or archaelysins; cd11375
Peptidase family M54, also called archaemetzincins or archaelysins; cd11375
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; pfam00884
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; pfam00884
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Dimerization/Docking domain of the Type I alpha Regulatory subunit of cAMP-dependent protein kinase; cd12101
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
Dimerization/Docking domain of the Type I alpha Regulatory subunit of cAMP-dependent protein kinase; cd12101
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
Dimerization/Docking domain of the Type I alpha Regulatory subunit of cAMP-dependent protein kinase; cd12101
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
C-terminal putative kinase domain of FAM20A; cd10469
C-terminal putative kinase domain of FAM20A; cd10469
ABC-2 family transporter protein; pfam12698
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; COG1131
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
ABC-2 family transporter protein; pfam12698
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; COG1131
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
ABC-2 family transporter protein; pfam12698
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; COG1131
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
ABC-2 family transporter protein; pfam12698
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; COG1131
ABC-2 family transporter protein; pfam12698
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
daunorubicin resistance ABC transporter ATP-binding subunit; TIGR01188
ABC-2 family transporter protein; pfam12698
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; COG1131
ABC-2 family transporter protein; pfam12698
Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; cl00454
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; COG1131
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
ABC-2 type transporter; pfam01061
ABC-2 family transporter protein; pfam12698
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; COG1131
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
ABC-2 family transporter protein; pfam12698
ABC-2 type transporter; pfam01061
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; COG1131
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; COG1131
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
ABC-2 family transporter protein; pfam12698
ABC-2 type transporter; pfam01061
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; COG1131
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; COG1131
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
Catalytic domain of the dual-specificity Protein Kinases, MAP kinase kinases 3 and 6; cd06617
Serine/Threonine protein kinases, catalytic domain; smart00220
Inward rectifier potassium channel; pfam01007
Inward rectifier potassium channel; pfam01007
Inward rectifier potassium channel; pfam01007
Inward rectifier potassium channel N-terminal; pfam08466
Inward rectifier potassium channel; pfam01007
Sox developmental protein N terminal; pfam12444
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
ZIP Zinc transporter; pfam02535
Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]
ZIP Zinc transporter; pfam02535
Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Vps51/Vps67; pfam08700
Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins [General function prediction only]; COG5084
zinc finger; smart00356
Zinc finger C-x8-C-x5-C-x3-H type (and similar); cl11592
P21-Rho-binding domain; pfam00786
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Ribosomal L38e protein family; pfam01781
Ribosomal L38e protein family; pfam01781
N-terminal domain of the protein encoded by the Drosophila tweety gene and related proteins, a family of chloride ion channels; cd07912
N-terminal domain of the protein encoded by the Drosophila tweety gene and related proteins, a family of chloride ion channels; cl12141
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Kinesin motor domain, KIP3-like subgroup. The yeast kinesin KIP3 plays a role in positioning the mitotic spindle. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Kinesins are microtubule-dependent...; cd01370
Kinesin motor, catalytic domain. ATPase; smart00129
BTB/POZ domain; pfam00651
BTB And C-terminal Kelch; smart00875
7 transmembrane receptor (rhodopsin family); pfam00001
Srg family chemoreceptor; pfam02118
7 transmembrane sweet-taste receptor of 3 GCPR; pfam00003
7 transmembrane sweet-taste receptor of 3 GCPR; pfam00003
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
Rab GTPase family 26 (Rab26); cd04112
GTPase SAR1 and related small G proteins [General function prediction only]
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR); cd05716
GTPase SAR1 and related small G proteins [General function prediction only]
Rab GTPase family 26 (Rab26); cd04112
GTPase SAR1 and related small G proteins [General function prediction only]
Rab GTPase family 26 (Rab26); cd04112
Rab GTPase family 26 (Rab26); cd04112
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
EBP50, C-terminal; pfam09007
Acetyltransferase (GNAT) domain; pfam13302
Acetyltransferase (GNAT) family; pfam00583
Transmembrane amino acid transporter protein; cl15776
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR2 subunit of NMDA receptor family; cd06378
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Ligand-gated ion channel; pfam00060
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
N-methyl D-aspartate receptor 2B3 C-terminus; pfam10565
ferredoxin-NADP+ reductase
NAD(P)-binding Rossmann-like domain; pfam13450
ferredoxin-NADP+ reductase
NAD(P)-binding Rossmann-like domain; pfam13450
ferredoxin-NADP+ reductase
NAD(P)-binding Rossmann-like domain; pfam13450
ferredoxin-NADP+ reductase
NAD(P)-binding Rossmann-like domain; pfam13450
ferredoxin-NADP+ reductase
ferredoxin-NADP+ reductase
NAD(P)-binding Rossmann-like domain; pfam13450
NADPH-dependent glutamate synthase beta chain and related oxidoreductases [Amino acid transport and metabolism / General function prediction only]; COG0493
Fatty acid desaturase; pfam00487
The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; cl00615
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
SAM domain of USH1G; cd09586
Sterile alpha motif; smart00454
Protein of unknown function, DUF270; pfam03189
Protein of unknown function, DUF270; pfam03189
Protein of unknown function, DUF270; pfam03189
Protein of unknown function, DUF270; pfam03189
consensus F-Y-R-[FM]-H-[SA]-X3[LF]-X-E-[VI]
High-temperature-induced dauer-formation protein; pfam12722
hypothetical protein; Provisional
ATP synthase D chain, mitochondrial (ATP5H); pfam05873
ATP synthase D chain, mitochondrial (ATP5H); pfam05873
BTB/POZ domain; cl02518
monocarboxylate transporter 1; TIGR00892
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Haloacid Dehalogenase-like Hydrolases; cl11391
5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C); pfam06941
Ubiquitin-like proteins; cl00155
Small ubiquitin-related modifier (SUMO); cd01763
Ubiquitin homologues; smart00213
Nup85 Nucleoporin; pfam07575
VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal...; cl02544
GAT domain; pfam03127
Adaptin C-terminal domain; smart00809
VHS domain family, GGA subfamily; GGA (Golgi-localized, Gamma-ear-containing, Arf-binding) comprise a subfamily of ubiquitously expressed, monomeric, motif-binding cargo/clathrin adaptor proteins. The VHS domain has a superhelical structure similar to...; cd03567
GAT domain; pfam03127
Adaptin C-terminal domain; smart00809
VHS domain family, GGA subfamily; GGA (Golgi-localized, Gamma-ear-containing, Arf-binding) comprise a subfamily of ubiquitously expressed, monomeric, motif-binding cargo/clathrin adaptor proteins. The VHS domain has a superhelical structure similar to...; cd03567
GAT domain; pfam03127
Adaptin C-terminal domain; smart00809
VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal...; cl02544
GAT domain; pfam03127
Adaptin C-terminal domain; smart00809
Ribosomal protein S7p/S5e; pfam00177
MIF4G domain; cl02652
MIF4G domain; cl02652
MIF4G domain; cl02652
MIF4G domain; cl02652
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins; cd09941
C-terminal Src homology 3 domain of Growth factor receptor-bound protein 2; cd11949
N-terminal Src homology 3 domain of Growth factor receptor-bound protein 2; cd11946
Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins; cd09941
C-terminal Src homology 3 domain of Growth factor receptor-bound protein 2; cd11949
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Src Homology 3 domain of CASK interacting protein 2; cd12063
SAM domain (Sterile alpha motif); pfam07647
SAM domain of caskin protein repeat 1; cd09497
SAM domain of caskin protein repeat 2; cd09498
Sterile alpha motif; smart00454
Ankyrin repeats (many copies); pfam13637
Ankyrin repeat; pfam00023
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Src Homology 3 domain of CASK interacting protein 2; cd12063
SAM domain (Sterile alpha motif); pfam07647
SAM domain of caskin protein repeat 1; cd09497
SAM domain of caskin protein repeat 2; cd09498
Sterile alpha motif; smart00454
tRNA-splicing endonuclease subunit sen54 N-term; pfam12928
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
LLGL2; pfam08366
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
LLGL2; pfam08366
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
LLGL2; pfam08366
DEAD-like helicases superfamily; smart00487
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
DEAD-like helicases superfamily; smart00487
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
DEAD-like helicases superfamily; smart00487
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
HCNGP-like protein; pfam07818
Integrin beta subunits (N-terminal portion of extracellular region); smart00187
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Integrin beta tail domain; pfam07965
Calx-beta domain; pfam03160
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Integrin beta subunits (N-terminal portion of extracellular region); smart00187
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Integrin beta tail domain; pfam07965
Calx-beta domain; pfam03160
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Integrin beta subunits (N-terminal portion of extracellular region); smart00187
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Integrin beta tail domain; pfam07965
Calx-beta domain; pfam03160
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
galactokinase; Provisional
Galactokinase galactose-binding signature; pfam10509
GHMP kinases C terminal; pfam08544
histone H3; Provisional
Zinc finger C-x8-C-x5-C-x3-H type (and similar); cl11592
Zinc finger, C3HC4 type (RING finger); pfam13920
C2 domain first repeat in Munc13 (mammalian uncoordinated)-like proteins; cd08676
Munc13 (mammalian uncoordinated) homology domain; pfam10540
C2 domain second repeat in Munc13 (mammalian uncoordinated)-like proteins; cd04009
GRAM domain; pfam02893
WW-domain ligand protein; pfam10349
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cd00021
SPRY-associated domain; cl02686
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
F0F1-type ATP synthase, subunit b [Energy production and conversion]; COG0711
ATP synthase B/B' CF(0); cl07975
Domain in SPla and the RYanodine Receptor; smart00449
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; cl00034
F0F1-type ATP synthase, subunit b [Energy production and conversion]; COG0711
ATP synthase B/B' CF(0); pfam00430
Domain in SPla and the RYanodine Receptor; smart00449
PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in eukaryotes; cd00866
chromosome segregation protein SMC, common bacterial type; TIGR02168
Peroxisomal acyl-CoA oxidase; cd01150
acyl-coenzyme A oxidase
Peroxisomal acyl-CoA oxidase; cd01150
acyl-coenzyme A oxidase
acyl-coenzyme A oxidase
Peroxisomal acyl-CoA oxidase; cd01150
cyclin-dependent kinase A; Provisional
Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase 2 and 3; cd07860
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Plectin repeat; pfam00681
Plectin repeat; smart00250
Plectin repeat; pfam00681
Plectin repeat; smart00250
Plectin repeat; pfam00681
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Neurotransmitter-gated ion-channel ligand binding domain; pfam02931
Exo70 exocyst complex subunit; pfam03081
Exo70 exocyst complex subunit; pfam03081
Exo70 exocyst complex subunit; pfam03081
Exo70 exocyst complex subunit; pfam03081
Exo70 exocyst complex subunit; pfam03081
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
High molecular weight glutenin subunit; pfam03157
ATPase involved in DNA repair [DNA replication, recombination, and repair]; COG0419
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism / Amino acid transport and metabolism]; COG0462
N-terminal domain of ribose phosphate pyrophosphokinase; pfam13793
Phosphoribosyl transferase (PRT)-type I domain; cd06223
Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; COG1597
Diacylglycerol kinase catalytic domain; pfam00781
Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; COG1597
Diacylglycerol kinase catalytic domain; pfam00781
Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; COG1597
Diacylglycerol kinase catalytic domain; pfam00781
Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; COG1597
Diacylglycerol kinase catalytic domain; pfam00781
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Acetyltransferase (GNAT) family; pfam00583
Acetyltransferase (GNAT) family; pfam00583
Rhomboid serine protease; pfam12595
Rhomboid family; pfam01694
Rhomboid serine protease; pfam12595
Rhomboid family; pfam01694
Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; cd01040
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Glycosyltransferase family 29 (sialyltransferase); pfam00777
JmjC domain, hydroxylase; pfam02373
JmjC domain, hydroxylase; pfam02373
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Ion channel regulatory protein UNC-93; pfam05978
Ion channel regulatory protein UNC-93; pfam05978
PRELI-like family; pfam04707
CRAL/TRIO, N-terminal domain; smart01100
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
PRELI-like family; pfam04707
CRAL/TRIO, N-terminal domain; smart01100
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
PRELI-like family; pfam04707
CRAL/TRIO, N-terminal domain; smart01100
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
PRELI-like family; pfam04707
CRAL/TRIO, N-terminal domain; smart01100
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
PRELI-like family; pfam04707
CRAL/TRIO, N-terminal domain; smart01100
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
PRELI-like family; pfam04707
CRAL/TRIO, N-terminal domain; smart01100
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
PRELI-like family; pfam04707
CRAL/TRIO, N-terminal domain; smart01100
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
CDC/Septin GTPase family; cd01850
Septin; pfam00735
CDC/Septin GTPase family; cd01850
Septin; pfam00735
CDC/Septin GTPase family; cd01850
Septin; pfam00735
CDC/Septin GTPase family; cd01850
Septin; pfam00735
CDC/Septin GTPase family; cd01850
Septin; pfam00735
CDC/Septin GTPase family; cd01850
Septin; pfam00735
CDC/Septin GTPase family; cd01850
Septin; pfam00735
Argonaute hook; pfam10427
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
M domain of GW182; pfam12938
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Argonaute hook; pfam10427
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
M domain of GW182; pfam12938
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
TMC domain; pfam07810
TMC domain; pfam07810
TMC domain; pfam07810
Membrane-associating domain; pfam01284
Thymidine kinase; pfam00265
Esterase/lipase [Lipid metabolism]; COG0657
Esterase/lipase [Lipid metabolism]; COG0657
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes; cd00022
PMP-22/EMP/MP20/Claudin tight junction; pfam13903
PMP-22/EMP/MP20/Claudin tight junction; pfam13903
PMP-22/EMP/MP20/Claudin family; cl15797
PMP-22/EMP/MP20/Claudin tight junction; pfam13903
Src homology 2 (SH2) domain found in  suppressor of cytokine signaling (SOCS) proteins; cd10384
SOCS (suppressors of cytokine signaling) box of SOCS3-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS3, like CIS1 and SOCS1, is involved in the...; cd03737
Catalytic domain, repeat 1, of eukaryotic PhosphatidylGlycerophosphate Synthases; cd09135
Catalytic domain, repeat 2, of eukaryotic phosphatidylglycerophosphate synthases; cd09137
Dynein heavy chain, N-terminal region 1; pfam08385
Dynein heavy chain, N-terminal region 2; pfam08393
Hydrolytic ATP binding site of dynein motor region D1; pfam12774
AAA domain (dynein-related subfamily); pfam07728
P-loop containing dynein motor region D3; pfam12775
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Microtubule-binding stalk of dynein motor; pfam12777
ATP-binding dynein motor region D5; pfam12781
Dynein heavy chain and region D6 of dynein motor; pfam03028
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor...; cd00171
Cytohesin Pleckstrin homology (PH) domain; cd01252
Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor...; cd00171
Cytohesin Pleckstrin homology (PH) domain; cd01252
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl...; cd02661
Ubiquitin carboxyl-terminal hydrolase; pfam00443
NTR domain, TIMP subfamily; TIMPs, or tissue inibitors of metalloproteases, are essential regulators of extracellular matrix turnover and remodeling. They form complexes with matrix metalloproteases (MMPs) and inactivate them irreversibly by...; cd03585
Scavenger receptor Cys-rich; smart00202
BTB And C-terminal Kelch; smart00875
Apyrase; pfam06079
Apyrase; pfam06079
Apyrase; pfam06079
Collagen triple helix repeat (20 copies); pfam01391
C1q domain; pfam00386
Collagen triple helix repeat (20 copies); pfam01391
C1q domain; pfam00386
Collagen triple helix repeat (20 copies); pfam01391
C1q domain; pfam00386
Collagen triple helix repeat (20 copies); pfam01391
C1q domain; pfam00386
Endo-beta-N-acetylglucosaminidase (ENGase) hydrolyzes the N-N'-diacetylchitobiosyl core of N-glycosylproteins.  The beta-1,4-glycosyl bond located between two N-acetylglucosamine residues is hydrolyzed such that N-acetylglucosamine 1 remains with the...; cd06547
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Calcitonin gene-related peptide regulator C terminal; pfam12414
Sulfatase; cl10460
Type I phosphodiesterase / nucleotide pyrophosphatase; pfam01663
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; cd00024
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
BRE1 E3 ubiquitin ligase; pfam08647
BRE1 E3 ubiquitin ligase; pfam08647
P or trefoil or TFF domain; Trefoil factor family domain peptides are mucin-associated molecules, largely found in epithelia of gastrointestinal tissues. Function is not known but it was originally identified from mucosal tissues, where it may have a...; cd00111
Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]
Galactose mutarotase-like; pfam13802
This family includes the following three closely related glycosyl hydrolase family 31 (GH31) enzymes: maltase-glucoamylase (MGAM), sucrase-isomaltase (SI), and lysosomal acid alpha-glucosidase (GAA), also known as acid-maltase. MGAM is one of the two...; cd06602
P or trefoil or TFF domain; Trefoil factor family domain peptides are mucin-associated molecules, largely found in epithelia of gastrointestinal tissues. Function is not known but it was originally identified from mucosal tissues, where it may have a...; cd00111
Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]
Galactose mutarotase-like; pfam13802
This family includes the following three closely related glycosyl hydrolase family 31 (GH31) enzymes: maltase-glucoamylase (MGAM), sucrase-isomaltase (SI), and lysosomal acid alpha-glucosidase (GAA), also known as acid-maltase. MGAM is one of the two...; cd06602
P or trefoil or TFF domain; Trefoil factor family domain peptides are mucin-associated molecules, largely found in epithelia of gastrointestinal tissues. Function is not known but it was originally identified from mucosal tissues, where it may have a...; cd00111
Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]
Galactose mutarotase-like; pfam13802
This family includes the following three closely related glycosyl hydrolase family 31 (GH31) enzymes: maltase-glucoamylase (MGAM), sucrase-isomaltase (SI), and lysosomal acid alpha-glucosidase (GAA), also known as acid-maltase. MGAM is one of the two...; cd06602
helicase 45; Provisional
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Caspase activation and recruitment domain of CARD14-like proteins; cd08806
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain superfamily; cl17036
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Caspase activation and recruitment domain of CARD14-like proteins; cd08806
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain superfamily; cl17036
Seryl-tRNA synthetase N-terminal domain; pfam02403
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; COG3119
Sulfatase; pfam00884
Sulfatase; cl10460
Sulfate transporter N-terminal domain with GLY motif; pfam13792
high affinity sulphate transporter 1; TIGR00815
Sulfate transporter family; pfam00916
Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; cd07042
Sulfate transporter N-terminal domain with GLY motif; pfam13792
high affinity sulphate transporter 1; TIGR00815
Sulfate transporter family; pfam00916
Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; cd07042
Sulfate transporter N-terminal domain with GLY motif; pfam13792
high affinity sulphate transporter 1; TIGR00815
Sulfate transporter family; pfam00916
Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; cd07042
Sulfate transporter N-terminal domain with GLY motif; pfam13792
high affinity sulphate transporter 1; TIGR00815
Sulfate transporter family; pfam00916
Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; cd07042
ATPases associated with a variety of cellular activities; smart00382
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
K+-dependent Na+/Ca+ exchanger; TIGR00927
Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; cd06559
Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; cd06559
Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; cd06559
Pentraxins are plasma proteins characterized by their pentameric discoid assembly and their Ca2+ dependent ligand binding, such as Serum amyloid P component (SAP) and C-reactive Protein (CRP), which are cytokine-inducible acute-phase proteins implicated...; cd00152
HEAT repeats; pfam13646
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Snf7; pfam03357
Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Insulin Receptor tyrosine kinase Substrate p53; cd07646
IRSp53/MIM homology domain; pfam08397
Src Homology 3 domain of Insulin Receptor tyrosine kinase Substrate p53; cd11915
Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Insulin Receptor tyrosine kinase Substrate p53; cd07646
IRSp53/MIM homology domain; pfam08397
Src Homology 3 domain of Insulin Receptor tyrosine kinase Substrate p53; cd11915
Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Insulin Receptor tyrosine kinase Substrate p53; cd07646
IRSp53/MIM homology domain; pfam08397
Src Homology 3 domain of Insulin Receptor tyrosine kinase Substrate p53; cd11915
Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Insulin Receptor tyrosine kinase Substrate p53; cd07646
IRSp53/MIM homology domain; pfam08397
Src Homology 3 domain of Insulin Receptor tyrosine kinase Substrate p53; cd11915
Protein kinase; unclassified specificity; smart00221
Catalytic domain of the Protein Tyrosine Kinases, Apoptosis-associated tyrosine kinases 1 and 3; cd05087
Protein kinase; unclassified specificity; smart00221
Catalytic domain of the Protein Tyrosine Kinases, Apoptosis-associated tyrosine kinases 1 and 3; cd05087
recombination and DNA strand exchange inhibitor protein; Reviewed
chromosome segregation protein SMC, common bacterial type; TIGR02168
recombination and DNA strand exchange inhibitor protein; Reviewed
chromosome segregation protein SMC, common bacterial type; TIGR02168
ENTH domain, Epsin Related family; composed of hypothetical proteins containing an ENTH-like domain. The epsin N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in...; cd03572
Transmembrane amino acid transporter protein; cl15776
Amino acid permeases [Amino acid transport and metabolism]; COG0814
Transmembrane amino acid transporter protein; cl15776
Amino acid permeases [Amino acid transport and metabolism]; COG0814
BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the...; cd04714
Actin; pfam00022
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Actin; pfam00022
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Fascin-like domain; members include actin-bundling/crosslinking proteins facsin, histoactophilin and singed;  identified in sea urchin, Drosophila, Xenopus, rodents, and humans; The fascin-like domain adopts a beta-trefoil topology and contains an...; cd00257
Fascin-like domain; members include actin-bundling/crosslinking proteins facsin, histoactophilin and singed;  identified in sea urchin, Drosophila, Xenopus, rodents, and humans; The fascin-like domain adopts a beta-trefoil topology and contains an...; cd00257
Fascin-like domain; members include actin-bundling/crosslinking proteins facsin, histoactophilin and singed;  identified in sea urchin, Drosophila, Xenopus, rodents, and humans; The fascin-like domain adopts a beta-trefoil topology and contains an...; cd00257
Fascin-like domain; members include actin-bundling/crosslinking proteins facsin, histoactophilin and singed;  identified in sea urchin, Drosophila, Xenopus, rodents, and humans; The fascin-like domain adopts a beta-trefoil topology and contains an...; cd00257
Fascin-like domain; members include actin-bundling/crosslinking proteins facsin, histoactophilin and singed;  identified in sea urchin, Drosophila, Xenopus, rodents, and humans; The fascin-like domain adopts a beta-trefoil topology and contains an...; cd00257
Fascin-like domain; members include actin-bundling/crosslinking proteins facsin, histoactophilin and singed;  identified in sea urchin, Drosophila, Xenopus, rodents, and humans; The fascin-like domain adopts a beta-trefoil topology and contains an...; cd00257
Fascin-like domain; members include actin-bundling/crosslinking proteins facsin, histoactophilin and singed;  identified in sea urchin, Drosophila, Xenopus, rodents, and humans; The fascin-like domain adopts a beta-trefoil topology and contains an...; cd00257
Fascin-like domain; members include actin-bundling/crosslinking proteins facsin, histoactophilin and singed;  identified in sea urchin, Drosophila, Xenopus, rodents, and humans; The fascin-like domain adopts a beta-trefoil topology and contains an...; cd00257
Nuclear pore localisation protein NPL4; pfam11543
NPL4 family, putative zinc binding region; pfam05020
Mov34/MPN/PAD-1 family: nuclear protein localization-4 (Npl4) domain; cd08061
NPL4 family; pfam05021
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), oculospanin_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment...; cd03167
Retinal cGMP phosphodiesterase, gamma subunit; pfam04868
Oxidoreductase-like protein, N-terminal; pfam09791
ADP-ribosylation factor(Arf)/Arf-like (Arl) small GTPases; cd00878
GTPase SAR1 and related small G proteins [General function prediction only]
VHS domain family, Hrs and Vps27p subfamily; composed of Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and its yeast homolog Vps27p (vacuolar protein sorting). The VHS domain, an essential part of Hrs/Vps27p, has a superhelical...; cd03569
Protein present in Fab1, YOTB, Vac1, and EEA1; smart00064
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Hepatocyte growth factor-regulated tyrosine kinase substrate; pfam12210
Double-stranded DNA-binding domain; cl00928
Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; cd00387
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Hormone receptor domain; pfam02793
7 transmembrane receptor (Secretin family); pfam00002
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
protein disulfide isomerases, eukaryotic; TIGR01130
Protein Disulfide Isomerase (PDIa) family, redox active TRX domains; composed of eukaryotic proteins involved in oxidative protein folding in the endoplasmic reticulum (ER) by acting as catalysts and folding assistants. Members of this family include PDI...; cd02961
Protein Disulfide Isomerase (PDIb) family, redox inactive TRX-like domain b; composed of eukaryotic proteins involved in oxidative protein folding in the endoplasmic reticulum (ER) by acting as catalysts and folding assistants. Members of this family...; cd02981
Protein Disulfide Isomerase (PDIb') family, redox inactive TRX-like domain b'; composed of eukaryotic proteins involved in oxidative protein folding in the endoplasmic reticulum (ER) by acting as catalysts and folding assistants. Members of this family...; cd02982
PDIa family, C-terminal TRX domain (a') subfamily; composed of the C-terminal redox active a' domains of PDI, ERp72, ERp57 (or ERp60) and EFP1. PDI, ERp72 and ERp57 are endoplasmic reticulum (ER)-resident eukaryotic proteins involved in oxidative protein...; cd02995
RHO protein GDP dissociation inhibitor; pfam02115
RHO protein GDP dissociation inhibitor; pfam02115
RHO protein GDP dissociation inhibitor; pfam02115
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cl15348
Anaphase-promoting complex subunit 11 RING-H2 finger; pfam12861
Anaphase-promoting complex subunit 11 RING-H2 finger; pfam12861
Anaphase-promoting complex subunit 11 RING-H2 finger; pfam12861
Anaphase-promoting complex subunit 11 RING-H2 finger; pfam12861
Anaphase-promoting complex subunit 11 RING-H2 finger; pfam12861
Anaphase-promoting complex subunit 11 RING-H2 finger; pfam12861
ethanolamine-phosphate cytidylyltransferase; Provisional
nucleotidyl transferase superfamily; cl00015
nucleotidyl transferase superfamily; cl00015
CTP:phosphoethanolamine cytidylyltransferase (ECT); cd02173
ethanolamine-phosphate cytidylyltransferase; Provisional
CTP:phosphocholine cytidylyltransferase; cd02174
CTP:phosphoethanolamine cytidylyltransferase (ECT); cd02173
ethanolamine-phosphate cytidylyltransferase; Provisional
CTP:phosphocholine cytidylyltransferase; cd02174
CTP:phosphoethanolamine cytidylyltransferase (ECT); cd02173
nucleotidyl transferase superfamily; cl00015
CTP:phosphoethanolamine cytidylyltransferase (ECT); cd02173
nucleotidyl transferase superfamily; cl00015
CTP:phosphoethanolamine cytidylyltransferase (ECT); cd02173
NAD-dependent deacetylase; Provisional
SIRT7: Eukaryotic and prokaryotic group (class4) which includes human sirtuin SIRT6, SIRT7, and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent...; cd01410
bZIP Maf transcription factor; pfam03131
bZIP Maf transcription factor; pfam03131
pyrroline-5-carboxylate reductase
pyrroline-5-carboxylate reductase; Reviewed
pyrroline-5-carboxylate reductase
pyrroline-5-carboxylate reductase; Reviewed
Membrane-associating domain; pfam01284
Pectinacetylesterase; pfam03283
GLUT4 regulating protein TUG; pfam11470
Ubiquitin-like proteins; cl00155
GLUT4 regulating protein TUG; pfam11470
Ubiquitin-like proteins; cl00155
CENP-S associating Centromere protein X; pfam09415
CENP-S associating Centromere protein X; pfam09415
CENP-S associating Centromere protein X; pfam09415
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
GTPase SAR1 and related small G proteins [General function prediction only]
Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)-like consists of Rac1, Rac2 and Rac3; cd01871
xylulose reductase-like, classical (c) SDRs; cd05351
short chain dehydrogenase; Provisional
xylulose reductase-like, classical (c) SDRs; cd05351
short chain dehydrogenase; Provisional
Fringe-like; pfam02434
26S proteasome subunit RPN7; pfam10602
PCI domain; pfam01399
26S proteasome subunit RPN7; pfam10602
PCI domain; pfam01399
Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; cd02801
Dihydrouridine synthase (Dus); pfam01207
putative zinc finger domain, LRP1 type; TIGR01623
Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]
polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; cd00833
Acyl transferase domain; pfam00698
Dehydratase domain in polyketide synthase (PKS) enzymes; smart00826
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Enoylreductase; smart00829
enoyl reductase of polyketide synthase; cd05195
beta-ketoacyl reductase (KR) domain of fatty acid synthase (FAS), subgroup 1, complex (x) SDRs; cd08954
Phosphopantetheine attachment site; smart00823
Thioesterase domain; pfam00975
chromosome segregation protein SMC, common bacterial type; TIGR02168
monocarboxylate transporter 1; TIGR00892
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
monocarboxylate transporter 1; TIGR00892
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
monocarboxylate transporter 1; TIGR00892
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
monocarboxylate transporter 1; TIGR00892
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
monocarboxylate transporter 1; TIGR00892
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
monocarboxylate transporter 1; TIGR00892
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; cd06174
Protein kinase domain; pfam00069
Catalytic domain of Protein Kinases; cd00180
Protein kinase domain; pfam00069
Catalytic domain of Protein Kinases; cd00180
Immunoglobulin V-set domain; pfam07686
Immunoglobulin variable domain (IgV); cd00099
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam13661
2OG-Fe(II) oxygenase superfamily; pfam13640
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam13661
Glycosyl hydrolase family 20 (GH20) catalytic domain of N-acetyl-beta-D-glucosaminidase (GcnA, also known as BhsA) and related proteins. GcnA  is an exoglucosidase which cleaves N-acetyl-beta-D-galactosamine (NAG) and N-acetyl-beta-D-galactosamine...; cd06565
Iron only hydrogenase large subunit, C-terminal domain [General function prediction only]
Iron only hydrogenase large subunit, C-terminal domain; pfam02906
Iron hydrogenase small subunit; smart00902
Iron only hydrogenase large subunit, C-terminal domain [General function prediction only]
Iron only hydrogenase large subunit, C-terminal domain; pfam02906
Iron hydrogenase small subunit; smart00902
Iron only hydrogenase large subunit, C-terminal domain; pfam02906
Iron hydrogenase small subunit; smart00902
Iron only hydrogenase large subunit, C-terminal domain; pfam02906
Iron hydrogenase small subunit; smart00902
Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; cd00060
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Rab GTPase family 40 (Rab40) contains Rab40a, Rab40b and Rab40c; cd04121
SOCS (suppressors of cytokine signaling) box of Rab40-like proteins. Rab40 is part of the Rab family of small GTP-binding proteins that form the largest family within the Ras superfamily. Rab proteins regulate vesicular trafficking pathways, behaving as...; cd03742
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Protein Kinases, catalytic domain; cl09925
Phosphotransferase enzyme family; pfam01636
Protein Kinases, catalytic domain; cl09925
Phosphotransferase enzyme family; pfam01636
HEAT-like repeat; pfam13513
Tubulin folding cofactor D C terminal; pfam12612
Predicted glycosyltransferases [General function prediction only]
Beta 1, 3-N-acetylglucosaminyltransferase is essential for the formation of poly-N-acetyllactosamine; cd06913
Ubiquitin homologues; smart00213
Ubiquitin-like proteins; cl00155
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl...; cd02657
Ubiquitin-like proteins; cl00155
Ubiquitin homologues; smart00213
Ubiquitin carboxyl-terminal hydrolase; pfam00443
A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl...; cd02657
THO complex subunit 1 transcription elongation factor; pfam11957
Death domain of Nuclear Matrix Protein P84; cd08318
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
centrin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
CLUSTERIN Beta chain; smart00030
Clusterin; pfam01093
CLUSTERIN alpha chain; smart00035
CLUSTERIN Beta chain; smart00030
Clusterin; pfam01093
CLUSTERIN alpha chain; smart00035
Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; cd00351
L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]
Human rTS beta is encoded by the rTS gene which, through alternative RNA splicing, also encodes rTS alpha whose mRNA is complementary to thymidylate synthase mRNA. rTS beta expression is associated with the production of small molecules that appear to...; cd03324
Human rTS beta is encoded by the rTS gene which, through alternative RNA splicing, also encodes rTS alpha whose mRNA is complementary to thymidylate synthase mRNA. rTS beta expression is associated with the production of small molecules that appear to...; cd03324
L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]
L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]
TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; cl09108
Src homology 3 domain of Yes Protein Tyrosine Kinase; cd12007
Src homology 2 (SH2) domain found in Yes; cd10366
Catalytic domain of Src kinase-like Protein Tyrosine Kinases; cd05034
Protein tyrosine kinase; pfam07714
Peptide hormone; cl02450
Glucagon like hormones; smart00070
Peptide hormone; cl02450
Glucagon like hormones; smart00070
MT-A70; cl01947
Protein involved in chromosome segregation, interacts with SMC proteins [Cell division and chromosome partitioning]; COG5185
HEC/Ndc80p family; pfam03801
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; pfam13589
SMC proteins Flexible Hinge Domain; smart00968
EMI domain; pfam07546
Collagen triple helix repeat (20 copies); pfam01391
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cl00147
lipin, N-terminal conserved region; pfam04571
LNS2 (Lipin/Ned1/Smp2); pfam08235
This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain and phosphatidylinositol transfer proteins; smart00775
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin; smart00409
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin like; smart00410
Immunoglobulin domain; cd00096
C-temrinal immunoglobulin (Ig)-like domain of myomesin and M-protein; cd05737
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin like; smart00410
Immunoglobulin domain; cd00096
C-temrinal immunoglobulin (Ig)-like domain of myomesin and M-protein; cd05737
Immunoglobulin I-set domain; pfam07679
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Guanylate-kinase-associated protein (GKAP) protein; pfam03359
Guanylate-kinase-associated protein (GKAP) protein; pfam03359
Guanylate-kinase-associated protein (GKAP) protein; pfam03359
Guanylate-kinase-associated protein (GKAP) protein; pfam03359
Guanylate-kinase-associated protein (GKAP) protein; pfam03359
Guanylate-kinase-associated protein (GKAP) protein; pfam03359
Guanylate-kinase-associated protein (GKAP) protein; pfam03359
Guanylate-kinase-associated protein (GKAP) protein; pfam03359
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Band 4.1 homologues; smart00295
FERM N-terminal domain; pfam09379
FERM central domain; pfam00373
FERM_C domain; cd00836
FERM adjacent (FA); pfam08736
SAB domain; pfam04382
4.1 protein C-terminal domain (CTD); pfam05902
Uncharacterized conserved protein (DUF2371); pfam10177
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2; smart00561
Zinc finger, C2HC type; pfam01530
Sterile alpha motif; smart00454
SAM domain of Scm-like-3MBT3,4 proteins of Polycomb group; cd09582
RhoGAP_ARHGAP18: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP18-like proteins. The function of ArhGAP18 is unknown. Small GTPases cluster into distinct families, and all act as molecular switches, active in their...; cd04391
GTPase-activator protein for Rho-like GTPases; smart00324
Laminin N-terminal (Domain VI); pfam00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin B (Domain IV); pfam00052
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin B (Domain IV); pfam00052
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin Domain I; pfam06008
Laminin Domain II; pfam06009
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Immunoglobulin like; smart00410
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Immunoglobulin like; smart00410
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Rab GTPase family 12 (Rab12); cd04120
Domain of unknown function (DUF4201); pfam13870
Protein of unknown function (DUF3166); pfam11365
Protein of unknown function (DUF3166); pfam11365
Respiratory-chain NADH dehydrogenase 24 Kd subunit; pfam01257
TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; cd03064
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Twisted gastrulation (Tsg) protein conserved region; pfam04668
RhoGap_RalBP1: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in RalBP1 proteins, also known as RLIP, RLIP76 or cytocentrin. RalBP1 plays an important role in endocytosis during interphase. During mitosis, RalBP1...; cd04381
GTPase-activator protein for Rho-like GTPases; smart00324
Rab-related GTPase family includes Rab5 and Rab22; regulates early endosome fusion; cd01860
Rab GTPase; Provisional
High molecular weight glutenin subunit; pfam03157
TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; cd02947
High molecular weight glutenin subunit; pfam03157
TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; cd02947
MSP (Major sperm protein) domain; pfam00635
MSP (Major sperm protein) domain; pfam00635
Protein of unknown function (DUF3595); pfam12166
G protein alpha subunit; smart00275
Alpha subunit of G proteins (guanine nucleotide binding); cd00066
G protein alpha subunit; smart00275
Alpha subunit of G proteins (guanine nucleotide binding); cd00066
G protein alpha subunit; smart00275
Alpha subunit of G proteins (guanine nucleotide binding); cd00066
Snf7; cl02305
Alpha subunit of G proteins (guanine nucleotide binding); cd00066
Calcineurin-like phosphoesterase; pfam00149
human MPPE1 and related proteins, metallophosphatase domain; cd08165
Calcineurin-like phosphoesterase; pfam00149
human MPPE1 and related proteins, metallophosphatase domain; cd08165
metallophosphatase superfamily, metallophosphatase domain; cl13995
IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; cd01639
CIDE_N domain of CIDE-A proteins. The CIDE_N (cell death-inducing DFF45-like effector, N-terminal) domain is found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins. These proteins are associated with the chromatin...; cd06539
tubulin beta chain; Provisional
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02187
FtsH Extracellular; pfam06480
ATP-dependent metalloprotease FtsH; TIGR01241
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Peptidase family M41; pfam01434
PRELI-like family; pfam04707
PRELI-like family; pfam04707
kinase non-catalytic C-lobe domain; smart00750
kinase non-catalytic C-lobe domain; smart00750
kinase non-catalytic C-lobe domain; smart00750
PAC2 family; pfam09754
PAC2 family; pfam09754
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Protein of unknown function (DUF1279); pfam06916
Protein of unknown function (DUF1279); pfam06916
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Catalytic domain of the Protein Serine/Threonine Kinase, Rho-associated coiled-coil containing protein kinase; cd05596
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Rho-associated coiled-coil containing protein kinase 1; cd11639
Rho Binding; pfam08912
Rok (Rho- associated kinase) pleckstrin homology (PH) domain; cd01242
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Pleckstrin homology-like domain; cl00273
zinc-finger of acetyl-transferase ESCO; pfam13878
ESCO1/2 acetyl-transferase; pfam13880
Sm protein D1; cd01724
alpha/beta hydrolase fold; pfam00561
Mib_herc2; pfam06701
Zinc finger, ZZ type. Zinc finger present in Drosophila Mind bomb (D-mib) and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Mind bomb is an E3 ubiqitin ligase that has...; cd02339
Mib_herc2; pfam06701
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13857
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Zinc finger, C3HC4 type (RING finger); pfam13920
Zinc finger, C3HC4 type (RING finger); pfam13923
Zinc finger, C3HC4 type (RING finger); pfam13920
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
GATA-type transcription activator, N-terminal; pfam05349
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C; cd00202
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C; cd00202
TSC-22/dip/bun family; cl01853
Tumour-suppressor protein CtIP N-terminal domain; pfam10482
Tumour-suppressor protein CtIP N-terminal domain; pfam10482
DNA repair protein endonuclease SAE2/CtIP C-terminus; pfam08573
Tumour-suppressor protein CtIP N-terminal domain; pfam10482
DNA repair protein endonuclease SAE2/CtIP C-terminus; pfam08573
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Nucleotide-sugar transporter [Carbohydrate transport and metabolism / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; COG5070
Serine/threonine protein kinase involved in cell cycle control [Signal transduction mechanisms / Cell division and chromosome partitioning]; COG1718
RIO kinase family; eukaryotic RIO3, catalytic domain. The RIO kinase catalytic domain family is part of a larger superfamily, that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein kinases (PKs); cd05146
Colon cancer-associated protein Mic1-like; pfam07035
Niemann-Pick C type protein family; TIGR00917
Sterol-sensing domain of SREBP cleavage-activation; pfam12349
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Laminin N-terminal domain (domain VI); smart00136
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin B (Domain IV); cl02548
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin Domain I; pfam06008
Laminin Domain I; pfam06008
Laminin Domain II; pfam06009
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin N-terminal domain (domain VI); smart00136
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domai; smart00180
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin B domain; smart00281
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin Domain I; pfam06008
Laminin Domain I; pfam06008
Laminin Domain II; pfam06009
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin Domain I; pfam06008
Laminin Domain II; pfam06009
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Laminin Domain I; pfam06008
Laminin Domain II; pfam06009
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cd00110
Protein of unknown function (DUF3808); pfam10300
Protein of unknown function (DUF3808); pfam10300
Dimerization/Docking domain of the sperm fibrous sheath proteins, Calcium-Binding tYrosine-phosphorylation Regulated protein and Sperm Protein 17; cd12100
Dimerization/Docking domain of the sperm fibrous sheath proteins, Calcium-Binding tYrosine-phosphorylation Regulated protein and Sperm Protein 17; cd12100
Dimerization/Docking domain of the sperm fibrous sheath proteins, Calcium-Binding tYrosine-phosphorylation Regulated protein and Sperm Protein 17; cd12100
Dimerization/Docking domain of the sperm fibrous sheath proteins, Calcium-Binding tYrosine-phosphorylation Regulated protein and Sperm Protein 17; cd12100
Dimerization/Docking domain of the sperm fibrous sheath proteins, Calcium-Binding tYrosine-phosphorylation Regulated protein and Sperm Protein 17; cd12100
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13857
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Pleckstrin homology-like domain; cl00273
Oxysterol-binding protein; pfam01237
Oxysterol-binding protein; pfam01237
Oxysterol-binding protein; pfam01237
domain in RING finger and WD repeat containing proteins and DEXDc-like helicases subfamily related to the UBCc domain; smart00591
Uncharacterized protein family UPF0029; pfam01205
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SSXT protein (N-terminal region); pfam05030
SSXT protein (N-terminal region); pfam05030
proteasome subunit alpha; Provisional
proteasome_alpha_type_7. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on...; cd03755
proteasome subunit alpha; Provisional
proteasome_alpha_type_7. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on...; cd03755
proteasome subunit alpha; Provisional
proteasome_alpha_type_7. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on...; cd03755
NHR1 homology to TAF; pfam07531
TATA Binding Protein (TBP) Associated Factor 4 (TAF4) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex; cd08045
BTB/POZ domain; cl02518
Domain of unknown function (DUF3504); pfam12012
BTB/POZ domain; cl02518
BTB/POZ domain; cl02518
BTB/POZ domain; cl02518
BTB/POZ domain; cl02518
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; cd00333
Sulfotransferase family; pfam03567
Cadherin prodomain like; pfam08758
Cadherin repeat-like domain; cl15786
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin domain; pfam00028
Cadherin cytoplasmic region; pfam01049
Cadherin prodomain like; smart01055
Cadherin domain; pfam00028
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin repeat-like domain; cl15786
Cadherin cytoplasmic region; pfam01049
Cadherin prodomain like; smart01055
Cadherin repeats; smart00112
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin repeat-like domain; cl15786
Cadherin prodomain like; smart01055
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin cytoplasmic region; pfam01049
Cadherin prodomain like; smart01055
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin prodomain like; smart01055
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin repeat-like domain; cl15786
Cadherin cytoplasmic region; pfam01049
Cadherin prodomain like; smart01055
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin repeat-like domain; cl15786
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin cytoplasmic region; pfam01049
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin cytoplasmic region; pfam01049
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin cytoplasmic region; pfam01049
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin cytoplasmic region; pfam01049
Transthyretin (TTR) is a 55 kDa protein responsible for the transport of thyroid hormones and retinol in vertebrates.  TTR distributes the two thyroid hormones T3 (3,5,3'-triiodo-L-thyronine) and T4 (Thyroxin, or 3,5,3',5'-tetraiodo-L-thyronine), as well...; cd05821
Beta-4-Galactosyltransferase is involved in the formation of the poly-N-acetyllactosamine core structures present in glycoproteins and glycosphingolipids; cd00899
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
ER-Golgi trafficking TRAPP I complex 85 kDa subunit; pfam12739
ER-Golgi trafficking TRAPP I complex 85 kDa subunit; pfam12739
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc-dependent metalloprotease, meprin_like subfamily. Meprins are membrane-bound or secreted extracellular proteases, which cleave a variety of targets, including peptides such as parathyroid hormone, gastrin, and cholecystokinin, cytokines such as...; cd04282
Astacin (Peptidase family M12A); pfam01400
Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members...; cd06263
Meprin family, Beta subunit, MATH domain; Meprins are multidomain extracellular metalloproteases capable of cleaving growth factors, cytokines, extracellular matrix proteins, and biologically active peptides. They are composed of two related subunits; cd03782
Cell-cycle sustaining, positive selection; pfam12736
SAM domain of GAREM subfamily; cd09525
Cell-cycle sustaining, positive selection; pfam12736
SAM domain of GAREM subfamily; cd09525
BTB/POZ domain; pfam00651
BTB/POZ domain; pfam00651
BTB And C-terminal Kelch; smart00875
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch motif; pfam01344
Kelch domain; smart00612
Kelch motif; pfam01344
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
Transcriptional enhancer, Asx-hm domain; pfam13919
PHD domain of transcriptional enhancer, Asx; pfam13922
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Seryl-tRNA synthetase N-terminal domain; pfam02403
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Seryl-tRNA synthetase N-terminal domain; pfam02403
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Seryl-tRNA synthetase N-terminal domain; pfam02403
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Seryl-tRNA synthetase N-terminal domain; pfam02403
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Seryl-tRNA synthetase N-terminal domain; pfam02403
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Seryl-tRNA synthetase N-terminal domain; pfam02403
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Seryl-tRNA synthetase N-terminal domain; pfam02403
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Seryl-tRNA synthetase N-terminal domain; pfam02403
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Seryl-tRNA synthetase N-terminal domain; pfam02403
EF hand; pfam09068
EF-hand; pfam09069
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
EF hand; pfam09068
EF-hand; pfam09069
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane...; cd02334
Seryl-tRNA synthetase N-terminal domain; pfam02403
Seryl-tRNA synthetase N-terminal domain; pfam02403
Seryl-tRNA synthetase N-terminal domain; pfam02403
seryl-tRNA synthetase; Provisional
seryl-tRNA synthetase; Provisional
Calponin homology (CH) domain; pfam00307
EB1-like C-terminal motif; pfam03271
Calponin homology (CH) domain; pfam00307
EB1-like C-terminal motif; pfam03271
Microtubule-binding protein involved in cell cycle control [Cell division and chromosome partitioning / Cytoskeleton]; COG5217
Calponin homology (CH) domain; pfam00307
EB1-like C-terminal motif; pfam03271
Calponin homology (CH) domain; pfam00307
EB1-like C-terminal motif; pfam03271
SCAN oligomerization domain; cd07936
SCAN oligomerization domain; cd07936
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
SCAN oligomerization domain; cd07936
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
SCAN oligomerization domain; cd07936
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
YL1 nuclear protein C-terminal domain; cl02154
YL1 nuclear protein C-terminal domain; cl02154
pp-GalNAc-T initiates the formation of mucin-type O-linked glycans; cd02510
Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; cd00161
Ricin-type beta-trefoil lectin domain; pfam00652
CID (CTD-Interacting Domain) domain family; CID is present in several RNA-processing factors such as Pcf11 and Nrd1. Pcf11 is a conserved and essential subunit of the yeast cleavage factor IA, which is required for polyadenylation-dependent 3'-RNA...; cd03562
ZIP Zinc transporter; pfam02535
Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]
ZIP Zinc transporter; pfam02535
Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; COG0520
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; cl00321
MOSC N-terminal beta barrel domain; pfam03476
MOSC domain; pfam03473
Formin Homology 2 Domain; pfam02181
Formin Homology 2 Domain; smart00498
SMI1 / KNR4 family; smart00860
phosphodiesterase; Provisional
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
C2 domain present in class III phosphatidylinositol 3-kinases (PI3Ks); cd08397
Phosphoinositide 3-kinase (PI3K) class III, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3Ks class III...; cd00870
Phosphoinositide 3-kinase family, accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear, but it has been suggested to be involved in substrate presentation. Phosphoinositide 3-kinases play an important role in...; cl00271
Phosphoinositide 3-kinase (PI3K), class III, catalytic domain; The PI3K catalytic domain family is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein kinases (PKs); cd00896
Phosphoinositide 3-kinase, catalytic domain; smart00146
Ras-like protein in all tissues (Rit), Ras-like protein in neurons (Rin) and Ras-related protein which interacts with calmodulin (Ric); cd04141
C2A domain first repeat present in Synaptotagmins 4 and 11; cd08388
C2 domain second repeat present in Synaptotagmin 4; cd08404
Urea transporter; pfam03253
Urea transporter; pfam03253
Urea transporter; pfam03253
Urea transporter; pfam03253
Urea transporter; pfam03253
Urea transporter; pfam03253
Urea transporter; pfam03253
Urea transporter; pfam03253
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Proline-Serine-Threonine Phosphatase-Interacting Protein 2; cd07672
F0F1 ATP synthase subunit alpha; Validated
ATP synthase alpha/beta family, beta-barrel domain; pfam02874
F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; cd01132
ATP synthase alpha/beta chain, C terminal domain; pfam00306
F0F1 ATP synthase subunit alpha; Validated
ATP synthase alpha/beta family, beta-barrel domain; pfam02874
F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; cd01132
ATP synthase alpha/beta chain, C terminal domain; pfam00306
F0F1 ATP synthase subunit alpha; Validated
ATP synthase alpha/beta family, beta-barrel domain; pfam02874
F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; cd01132
ATP synthase alpha/beta chain, C terminal domain; pfam00306
F0F1 ATP synthase subunit alpha; Validated
ATP synthase alpha/beta family, beta-barrel domain; pfam02874
F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; cd01132
ATP synthase alpha/beta chain, C terminal domain; pfam00306
F0F1 ATP synthase subunit alpha; Validated
ATP synthase alpha/beta family, beta-barrel domain; pfam02874
F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; cd01132
ATP synthase alpha/beta chain, C terminal domain; pfam00306
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2)  domain.  It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and...; cl00011
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2)  domain.  It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and...; cl00011
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2)  domain.  It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and...; cl00011
PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2)  domain.  It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and...; cl00011
PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2)  domain.  It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and...; cl00011
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2)  domain.  It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and...; cl00011
PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2)  domain.  It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and...; cl00011
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2)  domain.  It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and...; cl00011
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2)  domain.  It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and...; cl00011
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2)  domain.  It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and...; cl00011
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2)  domain.  It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and...; cl00011
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2)  domain.  It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and...; cl00011
PLAT/LH2 domain repeats of family of proteins with unknown function. In general, PLAT/LH2 consists of an eight stranded beta-barrel and it's proposed function is to mediate interaction with lipids or membrane bound proteins; cd01756
Glycosyltransferase family 29 (sialyltransferase); pfam00777
Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation; smart00513
PINIT domain; pfam14324
MIZ/SP-RING zinc finger; pfam02891
Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation; smart00513
PINIT domain; pfam14324
MIZ/SP-RING zinc finger; pfam02891
N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme; cd00183
RNA polymerase II transcription factor SIII (Elongin) subunit A; pfam06881
N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme; cd00183
RNA polymerase II transcription factor SIII (Elongin) subunit A; pfam06881
N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme; cd00183
RNA polymerase II transcription factor SIII (Elongin) subunit A; pfam06881
N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme; cd00183
RNA polymerase II transcription factor SIII (Elongin) subunit A; pfam06881
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
HAD-superfamily subfamily IIA hydrolase, TIGR01458
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427
Yos1-like; pfam08571
N-terminal Mad Homology 1 (MH1) domain in SMAD2 and SMAD3; cd10491
C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3; cd10985
N-terminal Mad Homology 1 (MH1) domain in SMAD2 and SMAD3; cd10491
C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3; cd10985
N-terminal Mad Homology 1 (MH1) domain in SMAD2 and SMAD3; cd10491
C-terminal Mad Homology 2 (MH2) domain in SMAD2 and SMAD3; cd10985
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
MIF4G domain; pfam02854
MIF4G domain; pfam02854
N-terminal Mad Homology 1 (MH1) domain in SMAD7; cd10494
C-terminal Mad Homology 2 (MH2) domain in SMAD7; cd10500
N-terminal Mad Homology 1 (MH1) domain in SMAD7; cd10494
C-terminal Mad Homology 2 (MH2) domain in SMAD7; cd10500
C-terminal Mad Homology 2 (MH2) domain in SMAD7; cd10500
C-terminal Mad Homology 2 (MH2) domain in SMAD7; cd10500
Dyggve-Melchior-Clausen syndrome protein; pfam09742
Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; cd00336
Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; cd00336
Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; cd00336
Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; cd00336
Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; cd00336
Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; cd00336
Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; cd00336
Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; cd00336
Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; cd00336
Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; cd00336
Pancreatic lipase-like enzymes.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is 'interfacial activation,' the...; cd00707
lipoprotein lipase; TIGR03230
PLAT/ LH2 domain present in lipoprotein lipase (LPL).  LPL is a key enzyme in catabolism of plasma lipoprotein triglycerides (TGs) and has therefeore has a profound influence on triglyceride and high-density lipoprotein (HDL) cholesterol levels in the...; cd01758
putative acyltransferase; Provisional
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; cd00751
Myosin. Large ATPases; smart00242
Myosin motor domain, type V myosins. Myosins V transport a variety of intracellular cargo processively along actin filaments, such as membraneous organelles and mRNA. This catalytic (head) domain has ATPase activity and belongs to the larger group of...; cd01380
Calmodulin-binding motif; smart00015
TPR/MLP1/MLP2-like protein; pfam07926
DIL domain; pfam01843
Tumour suppressor, Mitostatin; pfam13868
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
CXXC zinc finger domain; pfam02008
PHD-finger; pfam00628
CXXC zinc finger domain; pfam02008
CpG binding protein zinc finger C terminal domain; pfam12269
PHD-finger; pfam00628
CXXC zinc finger domain; pfam02008
CpG binding protein zinc finger C terminal domain; pfam12269
Protein of unknown function (DUF1395); pfam07160
Protein of unknown function (DUF1395); pfam07160
Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 and 6; cd07854
Protein kinase domain; pfam00069
NADP-dependent malic enzyme; Provisional
Malic enzyme, N-terminal domain; pfam00390
NAD(P) binding domain of malic enzyme (ME), subgroup 1; cd05312
NADP-dependent malic enzyme; Provisional
Malic enzyme, N-terminal domain; pfam00390
NAD(P) binding domain of malic enzyme (ME), subgroup 1; cd05312
ribonuclease Z; TIGR02651
N-terminal Mad Homology 1 (MH1) domain in SMAD4; cd10492
C-terminal Mad Homology 2 (MH2) domain in SMAD4; cd10498
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
First immunoglobulin (Ig)-like domain in neogenin and similar proteins; cd05722
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Neogenin C-terminus; pfam06583
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
C-terminal domain of methyl-CpG binding protein 2 and 3; pfam14048
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
Nucleotidyltransferase/DNA polymerase involved in DNA repair [DNA replication, recombination, and repair]; COG0389
DNA Polymerase iota; cd01703
Lipid-binding START domain of mammalian STARD6 and related proteins; cd08904
Rab GTPase family 27a (Rab27a); cd04127
Haloacid Dehalogenase-like Hydrolases; cl11391
Haloacid Dehalogenase-like Hydrolases; cl11391
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; cd02947
PITH domain; pfam06201
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
COMPASS (Complex proteins associated with Set1p) component shg1; pfam05205
Glycosyltransferase family 29 (sialyltransferase); pfam00777
CUT domain; pfam02376
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Ferrochelatase; pfam00762
Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; cd03411
Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; cd00419
Ferrochelatase; pfam00762
Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; cd03411
Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; cd00419
Aspartyl/asparaginyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; COG0017
AsnRS_cyto_like_N: N-terminal, anticodon recognition domain of the type found in human and Saccharomyces cerevisiae cytoplasmic asparaginyl-tRNA synthetase (AsnRS), in Brugia malayai AsnRs and, in various putative bacterial AsnRSs.  This domain is a...; cd04323
Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; cd00776
phospholipid-translocating P-type ATPase, flippase; TIGR01652
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
C2 domain present in the Human neural precursor cell-expressed, developmentally down-regulated 4 (NEDD4) and NEDD4-like (NEDD4L/NEDD42); cd04033
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
C2 domain present in the Human neural precursor cell-expressed, developmentally down-regulated 4 (NEDD4) and NEDD4-like (NEDD4L/NEDD42); cd04033
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
C2 domain present in the Human neural precursor cell-expressed, developmentally down-regulated 4 (NEDD4) and NEDD4-like (NEDD4L/NEDD42); cd04033
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
C2 domain present in the Human neural precursor cell-expressed, developmentally down-regulated 4 (NEDD4) and NEDD4-like (NEDD4L/NEDD42); cd04033
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
C2 domain present in the Human neural precursor cell-expressed, developmentally down-regulated 4 (NEDD4) and NEDD4-like (NEDD4L/NEDD42); cd04033
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
C2 domain; cl14603
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
C2 domain; cl14603
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
C2 domain; cl14603
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
C2 domain; cl14603
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
C2 domain; cl14603
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional...; cd00078
Domain Homologous to E6-AP Carboxyl Terminus with; smart00119
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Alpha-kinase family; smart00811
Death domain similar to that found in Mucosa-associated lymphoid tissue-lymphoma-translocation gene 1; cd08783
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Caspase domain; pfam00656
Death domain similar to that found in Mucosa-associated lymphoid tissue-lymphoma-translocation gene 1; cd08783
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Caspase domain; pfam00656
Zinc finger, C2H2 type; cl15478
Signal peptidase I [Intracellular trafficking and secretion]; COG0681
The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; cd06530
Bombesin-like peptide; pfam02044
Bombesin-like peptide; pfam02044
Bombesin-like peptide; pfam02044
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
OAR domain; pfam03826
Synaphin protein; pfam05835
ERGIC-53 and ERGL type 1 transmembrane proteins, N-terminal lectin domain; cd06902
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin cytoplasmic region; pfam01049
Zinc finger, C3HC4 type (RING finger); pfam13923
Ring finger domain; pfam13639
Uncharacterized proteins of the AP superfamily [General function prediction only]
Sulfatase; cl10460
Phosphatidylinositolglycan class N (PIG-N); pfam04987
Uncharacterized proteins of the AP superfamily [General function prediction only]
Sulfatase; cl10460
Phosphatidylinositolglycan class N (PIG-N); pfam04987
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cl12111
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cl12111
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cl12111
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cd00185
Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and...; cl12111
universal minicircle sequence binding protein (UMSBP); Provisional
Pleckstrin homology (PH) domain; cd00821
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; cd00143
Protein phosphatase 2C; pfam00481
apoptosis regulator; TIGR00865
Bcl-2 homology region 4; pfam02180
Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane...; cd06845
apoptosis regulator; TIGR00865
Bcl-2 homology region 4; pfam02180
Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane...; cd06845
3-ketodihydrosphingosine reductase (KDSR) and related proteins, classical (c) SDR; cd08939
short chain dehydrogenase; Provisional
MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in intracellular protein transport proteins of the AAA-ATPase family. The molecular function of the MIT domain is unclear; cd02678
MIT (microtubule interacting and transport) domain; pfam04212
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
ATPases associated with a variety of cellular activities; smart00382
Vps4 C terminal oligomerisation domain; pfam09336
Maspin (mammary serine proteinase inhibitor), a member of the serpin superfamily, with a multitude of effects on cells and tissues at an assortment of developmental stages. Maspin has tumor suppressing activity against breast and prostate cancer. In...; cd02057
serpin-like protein; Provisional
The ovalbumin_like group of serpins contains ovalbumin, the squamous cell carcinoma antigen 1 (SCCA1) and other closely related serpins of clade B of the serpin superfamily. Ovalbumin, the major protein component of avian egg white, is a non-inhibitory...; cd02059
SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate...; cl00137
The ovalbumin_like group of serpins contains ovalbumin, the squamous cell carcinoma antigen 1 (SCCA1) and other closely related serpins of clade B of the serpin superfamily. Ovalbumin, the major protein component of avian egg white, is a non-inhibitory...; cd02059
The ovalbumin_like group of serpins contains ovalbumin, the squamous cell carcinoma antigen 1 (SCCA1) and other closely related serpins of clade B of the serpin superfamily. Ovalbumin, the major protein component of avian egg white, is a non-inhibitory...; cd02059
The ovalbumin_like group of serpins contains ovalbumin, the squamous cell carcinoma antigen 1 (SCCA1) and other closely related serpins of clade B of the serpin superfamily. Ovalbumin, the major protein component of avian egg white, is a non-inhibitory...; cd02059
The ovalbumin_like group of serpins contains ovalbumin, the squamous cell carcinoma antigen 1 (SCCA1) and other closely related serpins of clade B of the serpin superfamily. Ovalbumin, the major protein component of avian egg white, is a non-inhibitory...; cd02059
The ovalbumin_like group of serpins contains ovalbumin, the squamous cell carcinoma antigen 1 (SCCA1) and other closely related serpins of clade B of the serpin superfamily. Ovalbumin, the major protein component of avian egg white, is a non-inhibitory...; cd02059
The ovalbumin_like group of serpins contains ovalbumin, the squamous cell carcinoma antigen 1 (SCCA1) and other closely related serpins of clade B of the serpin superfamily. Ovalbumin, the major protein component of avian egg white, is a non-inhibitory...; cd02059
SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate...; cl00137
Plasminogen Activator Inhibitor-2 (PAI-2). PAI-2 is a serine protease inhibitor that belongs to the ov-serpin branch of the serpin superfamily. It is is an effective inhibitor of urinary plasminogen activator (urokinase or uPA) and is involved in cell...; cd02058
Plasminogen Activator Inhibitor-2 (PAI-2). PAI-2 is a serine protease inhibitor that belongs to the ov-serpin branch of the serpin superfamily. It is is an effective inhibitor of urinary plasminogen activator (urokinase or uPA) and is involved in cell...; cd02058
Plasminogen Activator Inhibitor-2 (PAI-2). PAI-2 is a serine protease inhibitor that belongs to the ov-serpin branch of the serpin superfamily. It is is an effective inhibitor of urinary plasminogen activator (urokinase or uPA) and is involved in cell...; cd02058
serpin-like protein; Provisional
SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate...; cl00137
SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate...; cl00137
serpin-like protein; Provisional
SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate...; cl00137
serpin-like protein; Provisional
SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate...; cl00137
Cadherin repeats; smart00112
Cadherin repeats; smart00112
Cadherin repeats; smart00112
Cadherin repeats; smart00112
Cadherin repeats; smart00112
Cadherin repeats; smart00112
Cadherin repeats; smart00112
Cadherin repeats; smart00112
Cadherin repeats; smart00112
Cadherin repeats; smart00112
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin cytoplasmic region; pfam01049
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
Cadherin tandem repeat domain; cd11304
PDIa family, TMX3 subfamily; composed of eukaryotic proteins similar to human TMX3, a TRX related transmembrane protein containing one redox active TRX domain at the N-terminus and a classical ER retrieval sequence for type I transmembrane proteins at...; cd03000
Thioredoxin-like domain; pfam13848
Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; cl00388
chromosome segregation protein SMC, primarily archaeal type; TIGR02169
chromosome segregation protein SMC, primarily archaeal type; TIGR02169
Pleckstrin homology (PH) domain; cd00821
IRS-like phosphotyrosine-binding domain; cd00824
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Src homology 2 (SH2) domain found in  suppressor of cytokine signaling (SOCS) proteins; cd10387
SOCS (suppressors of cytokine signaling) box of SOCS6-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. The general function of the SOCS box is the...; cd03740
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cl00147
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
F-box-like; pfam12937
F-box-like; pfam12937
TIM21; pfam08294
Cytochrome b5-like Heme/Steroid binding domain; pfam00173
Cytochrome b5-like Heme/Steroid binding domain; pfam00173
Cytochrome b5-like Heme/Steroid binding domain; pfam00173
Pancreatitis induced protein 49 C terminal; pfam12260
M20 cytosolic nonspecific dipeptidases including anserinase and serum carnosinase; cd05676
hypothetical protein; Provisional
Zinc peptidases M18, M20, M28, and M42; cl14876
Zinc peptidases M18, M20, M28, and M42; cl14876
hypothetical protein; Provisional
M20 cytosolic nonspecific dipeptidases including anserinase and serum carnosinase; cd05676
Zinc-finger double domain; pfam13465
hypothetical protein
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
hypothetical protein
Mgc45594 gene product and other MDR family members; cd08250
NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; COG0604
C2H2 type zinc-finger (2 copies); pfam12756
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
FOG: Zn-finger [General function prediction only]
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Myelin basic protein; pfam01669
Myelin basic protein; pfam01669
Myelin basic protein; pfam01669
Myelin basic protein; pfam01669
Myelin basic protein; pfam01669
Myelin basic protein; pfam01669
7 transmembrane receptor (rhodopsin family); pfam00001
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
phospholipid-translocating P-type ATPase, flippase; TIGR01652
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins; cd07881
Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; cl15674
N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins; cd07881
Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; cl15674
N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins; cd07881
Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; cl15674
N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins; cd07881
Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; cl15674
N-terminal sub-domain of the Rel homology domain (RHD); cl08275
Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; cl15674
The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; cd06850
FCP1-like phosphatase, phosphatase domain; TIGR02250
catalytic domain of ctd-like phosphatases; smart00577
Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; cd00027
FCP1, C-terminal; pfam09309
The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; cd06850
FCP1-like phosphatase, phosphatase domain; TIGR02250
catalytic domain of ctd-like phosphatases; smart00577
Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; cd00027
FCP1, C-terminal; pfam09309
FCP1-like phosphatase, phosphatase domain; TIGR02250
catalytic domain of ctd-like phosphatases; smart00577
Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; cd00027
FCP1, C-terminal; pfam09309
BTB/POZ domain; cl02518
Ion transport protein; pfam00520
Ion channel; pfam07885
PQ loop repeat; pfam04193
PQ loop repeat; pfam04193
PQ loop repeat; pfam04193
PQ loop repeat; pfam04193
PQ loop repeat; pfam04193
Heat shock factor binding protein 1; pfam06825
Dim1 family; Dim1 is also referred to as U5 small nuclear ribonucleoprotein particle (snRNP)-specific 15kD protein. It is a component of U5 snRNP, which pre-assembles with U4/U6 snRNPs to form a [U4/U6:U5] tri-snRNP complex required for pre-mRNA splicing; cd02954
Ribosome-binding factor A; pfam02033
GatB domain; cl11497
Ribosome-binding factor A; cl00542
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
The PB1 domain is an essential part of Par6 protein which in complex with Par3 and aPKC proteins is crucial for establishment of apical-basal polarity of animal cells. The PB1 domain is a modular domain mediating specific protein-protein interactions...; cd06403
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
ELM2 domain; pfam01448
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; smart00717
Myb-Like Dna-Binding Domain of MTA3 and related proteins; cd11661
C2 domain; cd00030
SHC phosphotyrosine-binding (PTB) domain; cd01209
Src homology 2 (SH2) domain found in SH2 adaptor protein C (SHC); cd09925
Immunoglobulin domain; cl11960
Adhesion molecule, immunoglobulin-like; pfam09085
length polymorphism due to repeat motif in mucin-like region
Immunoglobulin domain; cl11960
Adhesion molecule, immunoglobulin-like; pfam09085
Dimerization/Docking domain of the Regulatory subunit of cAMP-dependent protein kinase and similar domains; cl02594
Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin...; cd00195
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
Ion transport protein N-terminal; pfam08412
Ion transport protein; pfam00520
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
DNA-dependent RNA polymerase; pfam00940
Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate...; cd00058
zinc-finger; pfam14369
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cl00097
Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cd00104
Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cl00097
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Paralemmin; pfam03285
Paralemmin; pfam03285
hnRNP-L/PTB/hephaestus splicing factor family; TIGR01649
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
hnRNP-L/PTB/hephaestus splicing factor family; TIGR01649
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
hnRNP-L/PTB/hephaestus splicing factor family; TIGR01649
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
WD40 repeats; smart00320
Mediator complex subunit 16; pfam11635
R3H-associated N-terminal domain; pfam13902
R3H domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. R3H domains are found in proteins together with ATPase domains, SF1 helicase domains, SF2 DEAH helicase domains, Cys-rich...; cl00297
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
BRIGHT, ARID (A/T-rich interaction domain) domain; smart00501
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Alternative WD40 repeat motif; pfam14077
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the NR3 subunit of NMDA receptor family; cd06377
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Ligand-gated ion channel; pfam00060
Eukaryotic homologues of bacterial periplasmic substrate binding proteins; smart00079
Tumour-associated protein; pfam09746
Tumour-associated protein; pfam09746
Calponin [Cytoskeleton]; COG5199
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin family repeat; pfam00402
Calponin family repeat; pfam00402
Calponin family repeat; pfam00402
Calponin [Cytoskeleton]; COG5199
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin family repeat; pfam00402
Calponin family repeat; pfam00402
Calponin family repeat; pfam00402
ABC-2 family transporter protein; pfam12698
ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; COG1122
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
ABC-2 family transporter protein; pfam12698
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; COG1131
The ABCA subfamily mediates the transport of a variety of lipid compounds.  Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency; cd03263
Fes/CIP4 homology domain; smart00055
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when...; cl02570
GTPase-activator protein for Rho-like GTPases; smart00324
Fes/CIP4 homology domain; smart00055
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when...; cl02570
GTPase-activator protein for Rho-like GTPases; smart00324
DNA-directed RNA polymerase II subunit family protein; Provisional
RNA polymerase Rpb5, N-terminal domain; pfam03871
RNA polymerase Rpb5, C-terminal domain; pfam01191
Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; cd00340
Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; cd00340
Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; cd00340
P-loop containing NTP hydrolase pore-1; pfam13872
Helicase_C-like; pfam13871
P-loop containing NTP hydrolase pore-1; pfam13872
Helicase_C-like; pfam13871
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) [Energy production and conversion]; COG0355
ATP synthase, Delta/Epsilon chain, beta-sandwich domain; pfam02823
F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) [Energy production and conversion]; COG0355
ATP synthase, Delta/Epsilon chain, beta-sandwich domain; pfam02823
Ubiquitin-like domain of midnolin; cd01804
Ubiquitin homologues; smart00213
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Protein of unknown function (DUF1180); pfam06679
Receptor Binding Domain of Ephrin A; cd10425
Mutated melanoma-associated antigen 1 (MUM-1) is a melanoma-associated antigen (MAA).  MUM-1 belongs to the mutated or aberrantly expressed type of MAAs, along with antigens such as CDK4, beta-catenin, gp100-in4, p15, and N-acetylglucosaminyltransferase...; cd06080
NADH dehydrogenase subunit B; Validated
NADH-quinone oxidoreductase, B subunit; TIGR01957
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
30S ribosomal protein S19P; Provisional; PRK04038
Ribosomal protein S19; cl00350
Adenomatous polyposis coli tumour suppressor protein; pfam11414
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cl02500
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
APC cysteine-rich region; pfam05923
APC basic domain; pfam05956
Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; COG1404
Peptidase S8 family domain in Protein convertases; cd04059
Proprotein convertase P-domain; pfam01483
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors; cd00064
TB2/DP1, HVA22 family; pfam03134
ADAM cysteine-rich; cl15456
ADAM-TS Spacer 1; pfam05986
NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the...; cd03523
Protein Kinases, catalytic domain; cl09925
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
MeCP2, MBD1, MBD2, MBD3, and MBD4 are members of a protein family that share the methyl-CpG-binding domain (MBD). The MBD, consists of about 70 residues and is defined as the minimal region required for binding to methylated DNA by a methyl-CpG-binding...; cd01396
C-terminal domain of methyl-CpG binding protein 2 and 3; pfam14048
Ubiquinol-cytochrome C reductase complex, 6.4kD protein; pfam08997
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
CUT domain; pfam02376
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
phospholipid-translocating P-type ATPase, flippase; TIGR01652
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid Dehalogenase-like Hydrolases; cl11391
phospholipid-translocating P-type ATPase, flippase; TIGR01652
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid Dehalogenase-like Hydrolases; cl11391
DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins; cd06145
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Alpha/beta hydrolase family; pfam12695
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Alpha/beta hydrolase family; pfam12695
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; cd01285
SCAMP family; pfam04144
putative serine/threonine kinase; Provisional
Catalytic domain of Protein Kinases; cd00180
Casein kinase 1 gamma C terminal; pfam12605
BTB/POZ domain; pfam00651
BTB And C-terminal Kelch; smart00875
PHR domain; pfam08005
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Mob1/phocein family; pfam03637
Adaptin N terminal region; pfam01602
Bovine leukaemia virus receptor (BLVR); pfam06375
Bovine leukaemia virus receptor (BLVR); pfam06375
Adaptin N terminal region; pfam01602
Bovine leukaemia virus receptor (BLVR); pfam06375
Bovine leukaemia virus receptor (BLVR); pfam06375
Histone methylation protein DOT1; pfam08123
Rhoptry-associated protein 1 (RAP-1); pfam07218
Pleckstrin homology (PH) domain; cd00821
Splicing factor 3a, subunit 2 [RNA processing and modification]; COG5246
U1-like zinc finger; smart00451
Cactus-binding C-terminus of cactin protein; cl10717
Anti-Mullerian hormone, N terminal region; pfam04709
Transforming growth factor-beta (TGF-beta) family; smart00204
Ornithine decarboxylase antizyme; pfam02100
Leucine rich repeat N-terminal domain; smart00013
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Like-Sm protein 7; cd01729
PA_hSPPL_like: Protease-associated domain containing human signal peptide peptidase-like (hSPPL)-like. This group contains various PA domain-containing proteins similar to hSPPL2a and 2b. These SPPLs are GxGD aspartic proteases. SPPL2a is sorted to the...; cd02129
Signal peptide peptidase; pfam04258
E4 protein; Provisional
PA_hSPPL_like: Protease-associated domain containing human signal peptide peptidase-like (hSPPL)-like. This group contains various PA domain-containing proteins similar to hSPPL2a and 2b. These SPPLs are GxGD aspartic proteases. SPPL2a is sorted to the...; cd02129
Signal peptide peptidase; pfam04258
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Tim10/DDP family zinc finger; pfam02953
Intermediate filament protein; pfam00038
Lamin Tail Domain; pfam00932
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; pfam01248
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors; cd00068
GTPase SAR1 and related small G proteins [General function prediction only]
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
ZIP Zinc transporter; pfam02535
ZIP Zinc transporter; pfam02535
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Peptidase M3 Thimet oligopeptidase (TOP) also includes neurolysin; cd06455
Zn-dependent oligopeptidases [Amino acid transport and metabolism]; COG0339
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Groucho/TLE N-terminal Q-rich domain; pfam03920
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Groucho/TLE N-terminal Q-rich domain; pfam03920
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Groucho/TLE N-terminal Q-rich domain; pfam03920
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
Groucho/TLE N-terminal Q-rich domain; pfam03920
Groucho/TLE N-terminal Q-rich domain; pfam03920
Groucho/TLE N-terminal Q-rich domain; pfam03920
G protein alpha subunit; smart00275
Alpha subunit of G proteins (guanine nucleotide binding); cd00066
G protein alpha subunit; smart00275
Alpha subunit of G proteins (guanine nucleotide binding); cd00066
7 transmembrane receptor (rhodopsin family); pfam00001
M28 Zn-Peptidase Nicalin, Nicastrin-like protein; cd03882
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
ELAV/HuD family splicing factor; TIGR01661
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
polyadenylate binding protein, human types 1, 2, 3, 4 family; TIGR01628
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Nuclear factor I protein pre-N-terminus; pfam10524
N-terminal Mad Homology 1 (MH1) domain; cl00055
CTF/NF-I family transcription modulation region; pfam00859
Nuclear factor I protein pre-N-terminus; pfam10524
N-terminal Mad Homology 1 (MH1) domain; cl00055
CTF/NF-I family transcription modulation region; pfam00859
Nuclear factor I protein pre-N-terminus; pfam10524
N-terminal Mad Homology 1 (MH1) domain; cl00055
CTF/NF-I family transcription modulation region; pfam00859
Nuclear factor I protein pre-N-terminus; pfam10524
N-terminal Mad Homology 1 (MH1) domain; cl00055
CTF/NF-I family transcription modulation region; pfam00859
Nuclear factor I protein pre-N-terminus; pfam10524
N-terminal Mad Homology 1 (MH1) domain; cl00055
CTF/NF-I family transcription modulation region; pfam00859
HEAT repeats; pfam13646
E-Z type HEAT repeats; smart00567
E-Z type HEAT repeats; smart00567
HEAT repeats; pfam13646
E-Z type HEAT repeats; smart00567
HEAT repeats; pfam13646
E-Z type HEAT repeats; smart00567
E-Z type HEAT repeats; smart00567
HEAT repeats; pfam13646
E-Z type HEAT repeats; smart00567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
melibiose:sodium symporter; Provisional; cl15392
MFS/sugar transport protein; pfam13347
melibiose:sodium symporter; Provisional; cl15392
MFS/sugar transport protein; pfam13347
melibiose:sodium symporter; Provisional; cl15392
MFS/sugar transport protein; pfam13347
HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone...; cd01390
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
Conserved mid region of cactin; pfam10312
Cactus-binding C-terminus of cactin protein; pfam09732
Conserved mid region of cactin; pfam10312
Cactus-binding C-terminus of cactin protein; pfam09732
Phosphatidylinositol phosphate kinases (PIPK) catalyze the phosphorylation of phosphatidylinositol phosphate on the fourth or fifth hydroxyl of the inositol ring, to form phosphatidylinositol bisphosphate. CD alignment  includes type II...; cd00139
Phosphatidylinositol phosphate kinases (PIPK) catalyze the phosphorylation of phosphatidylinositol phosphate on the fourth or fifth hydroxyl of the inositol ring, to form phosphatidylinositol bisphosphate. CD alignment  includes type II...; cl02572
Phosphatidylinositol phosphate kinases (PIPK) catalyze the phosphorylation of phosphatidylinositol phosphate on the fourth or fifth hydroxyl of the inositol ring, to form phosphatidylinositol bisphosphate. CD alignment  includes type II...; cd00139
Phosphatidylinositol phosphate kinases (PIPK) catalyze the phosphorylation of phosphatidylinositol phosphate on the fourth or fifth hydroxyl of the inositol ring, to form phosphatidylinositol bisphosphate. CD alignment  includes type II...; cl02572
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src homology 3 domain of the Tight junction protein, Zonula occludens protein 3; cd12028
Guanylate kinase homologues; smart00072
Guanylate kinase; pfam00625
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src homology 3 domain of the Tight junction protein, Zonula occludens protein 3; cd12028
Guanylate kinase homologues; smart00072
Guanylate kinase; pfam00625
Pleckstrin homology-like domain; cl00273
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Mitochondrial ribosomal protein L37; pfam08561
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Src Homology 3 domain superfamily; cl17036
Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk); cd09937
Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase; cd05083
Protein kinase; unclassified specificity; smart00221
Src Homology 3 domain superfamily; cl17036
Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk); cd09937
Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase; cd05083
Protein kinase; unclassified specificity; smart00221
Src Homology 3 domain superfamily; cl17036
Src homology 2 (SH2) domain found in Carboxyl-Terminal Src Kinase (Csk); cd09937
Catalytic domain of the Protein Tyrosine Kinase, Csk homologous kinase; cd05083
Protein kinase; unclassified specificity; smart00221
U1-like zinc finger; smart00451
U1-like zinc finger; smart00451
U1-like zinc finger; smart00451
domain in DSRM or ZnF_C2H2 domain containing proteins; smart00572
Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2; pfam12496
Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to...; cd00170
Nicotinamide riboside kinase (NRK) is an enzyme involved in the metabolism of nicotinamide adenine dinucleotide (NAD+). This enzyme catalyzes the phosphorylation of nicotinamide riboside (NR) to form nicotinamide mononucleotide (NMN). It defines the NR...; cd02024
AAA domain; pfam13238
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
elongation factor 2; Provisional
Elongation Factor 2 (EF2) in archaea and eukarya; cd01885
EF2_snRNP_like_II: this subfamily represents domain II of elongation factor (EF) EF-2 found eukaryotes and archaea and, the C-terminal portion of the spliceosomal human 116kD U5 small nuclear ribonucleoprotein (snRNP) protein (U5-116 kD) and, its yeast...; cd03700
This family represents domain IV of archaeal and eukaryotic elongation factor 2 (aeEF-2) and of an evolutionarily conserved U5 snRNP-specific protein. U5 snRNP is a GTP-binding factor closely related to the ribosomal translocase EF-2. In complex with GTP; cd01681
eEF2_snRNP_like_C: this family represents a C-terminal domain of eukaryotic elongation factor 2 (eEF-2) and a homologous domain of the spliceosomal human 116kD U5 small nuclear ribonucleoprotein (snRNP) protein (U5-116 kD) and, its yeast counterpart...; cd04096
Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation; smart00513
PINIT domain; pfam14324
MIZ/SP-RING zinc finger; pfam02891
BTB/POZ domain; pfam00651
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
basic region leucin zipper; smart00338
NAD-dependent deacetylase; Provisional
SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; cl00195
NAD-dependent deacetylase; Provisional
SIRT7: Eukaryotic and prokaryotic group (class4) which includes human sirtuin SIRT6, SIRT7, and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent...; cd01410
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13857
Fibronectin type 3 domain; smart00060
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Family of unknown function (DUF572); pfam04502
Uncharacterized conserved protein [Function unknown]
Src homology 2 domain found in SH2 domain-containing adapter proteins D (SHD); cd10390
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Domain in SPla and the RYanodine Receptor; smart00449
Src homology 2 domain found in Signal-transducing adaptor protein 2 (STAP2); cd10404
Src homology 2 domain found in Signal-transducing adaptor protein 2 (STAP2); cd10404
Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase; cd08067
Mpr1p, Pad1p N-terminal (MPN) domains; cl13996
BAR domain; smart00721
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; cl12013
Src homology 3 domain of Endophilin-A; cd11803
BAR domain; smart00721
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; cl12013
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; cl12013
Src homology 3 domain of Endophilin-A; cd11803
BAR domain; smart00721
The Bin/Amphiphysin/Rvs (BAR) domain of Endophilin-A2; cd07614
Src homology 3 domain of Endophilin-A; cd11803
Chromatin assembly factor 1 p150 subunit; pfam11600
Chromatin assembly factor 1 subunit A; pfam12253
PNGase/UBA or UBX (PUB) domain of UBXD1; cd10460
Ubiquitin-like proteins; cl00155
PNGase/UBA or UBX (PUB) domain of UBXD1; cd10460
Ubiquitin-like proteins; cl00155
The PWWP domain is an essential part of the Hepatoma Derived Growth Factor (HDGF) family of proteins, and is necessary for DNA binding by HDGF. This family of endogenous nuclear-targeted mitogens includes HRP (HDGF-related proteins 1, 2, 3, 4, or HPR1; cd05834
Lens epithelium-derived growth factor (LEDGF); pfam11467
The PWWP domain is an essential part of the Hepatoma Derived Growth Factor (HDGF) family of proteins, and is necessary for DNA binding by HDGF. This family of endogenous nuclear-targeted mitogens includes HRP (HDGF-related proteins 1, 2, 3, 4, or HPR1; cd05834
Lens epithelium-derived growth factor (LEDGF); pfam11467
Perilipin family; pfam03036
Perilipin family; pfam03036
Perilipin family; pfam03036
Perilipin family; pfam03036
Perilipin family; pfam03036
Perilipin family; pfam03036
Perilipin family; pfam03036
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
The Sema domain, a protein interacting module, of semaphorin 6B (Sema6B); cd11267
semaphorin domain; smart00630
Plexin repeat; cl02601
Domain of unknown function (DUF758); pfam05527
Domain of unknown function (DUF758); pfam05527
Uncharacterized protein family UPF0556; pfam10572
Dipeptidyl peptidase IV (DPP IV) N-terminal region; pfam00930
Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; COG1506
Prolyl oligopeptidase family; pfam00326
Ankyrin repeats (many copies); pfam13637
Ankyrin repeat; pfam00023
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13857
Ankyrin repeats (many copies); pfam13857
TIR domain; cl15770
RIP homotypic interaction motif; pfam12721
Perilipin family; pfam03036
Perilipin family; pfam03036
Perilipin family; pfam03036
Arrestin (or S-antigen), N-terminal domain; cl02844
Arrestin (or S-antigen), C-terminal domain; pfam02752
amino-terminal ubiquitin-like domain of  Np95 and NIRF; cd01797
Ubiquitin family; pfam00240
Protein of unknown function (DUF3590); pfam12148
PHD-finger; pfam00628
YDG/SRA domain; pfam02182
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
amino-terminal ubiquitin-like domain of  Np95 and NIRF; cd01797
Ubiquitin family; pfam00240
Protein of unknown function (DUF3590); pfam12148
PHD-finger; pfam00628
YDG/SRA domain; pfam02182
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
Zinc finger, C3HC4 type (RING finger); pfam13923
Small domain found in the jumonji family of transcription factors; smart00545
JmjC domain, hydroxylase; pfam02373
PHD-finger; pfam13831
PHD-zinc-finger like domain; pfam13832
PHD zinc finger; smart00249
Tudor domain; smart00333
Tudor domain; smart00333
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Second immunoglobulin (Ig)-like domain of  the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR; cd05738
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR; cd05739
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Second immunoglobulin (Ig)-like domain of  the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR; cd05738
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR; cd05739
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Second immunoglobulin (Ig)-like domain of  the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR; cd05738
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR; cd05739
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR; cd05739
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
Protein tyrosine phosphatase, catalytic domain; smart00194
Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; cd00047
PA_C-RZF_ like: Protease-associated (PA) domain C_RZF-like. This group includes various PA domain-containing proteins similar to C-RZF (chicken embryo RING zinc finger) protein. These proteins contain a C3H2C3 RING finger. C-RZF is expressed in embryo...; cd02123
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
SAP domain; pfam02037
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
SAP domain; pfam02037
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
SAP domain; pfam02037
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
SAP domain; pfam02037
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
SAP domain; pfam02037
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Putative binding domain; pfam13900
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
Ribosomal protein L36e; pfam01158
60S ribosomal protein L36; Provisional
Ribosomal protein L36e; pfam01158
60S ribosomal protein L36; Provisional
Found in ATP-dependent protease La (LON); smart00464
ATP-dependent protease La; TIGR00763
Found in ATP-dependent protease La (LON); smart00464
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
Subunit ChlI of Mg-chelatase; cl12214
tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]
Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; cd02801
tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]
Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; cd02801
Transforming growth factor beta like domain; pfam00019
Glycosyltransferase family 10 (fucosyltransferase); pfam00852
Glycosyltransferase family 10 (fucosyltransferase); pfam00852
Glycosyltransferase family 10 (fucosyltransferase); pfam00852
Glycosyltransferase family 10 (fucosyltransferase); pfam00852
Glycosyltransferase family 10 (fucosyltransferase); pfam00852
Glycosyltransferase family 10 (fucosyltransferase); pfam00852
Glycosyltransferase family 10 (fucosyltransferase); pfam00852
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
EF-hand domain pair; pfam13499
calmodulin; Provisional
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Ran-binding domain; cd00835
Ran-binding domain; cd00835
Ran-binding domain; cd00835
RFX1 transcription activation region; pfam04589
RFX DNA-binding domain; pfam02257
RFX1 transcription activation region; pfam04589
RFX DNA-binding domain; pfam02257
Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; COG1022
AMP-binding enzyme; pfam00501
YEATS family; pfam03366
Ceramidase; pfam05875
Clp protease; pfam00574
Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; cd07017
2OG-Fe(II) oxygenase superfamily; cl15773
Transforming growth factor beta like domain; pfam00019
Transcription initiation factor IIF, alpha subunit, N-terminal region of RAP74. Subunit of transcription initiation complex involved in initiation, elongation and promoter escape.Tetramer of 2 alpha and 2 beta TFIIF subunits interacts directly with RNA...; cd00240
Transcription initiation factor IIF, alpha subunit, N-terminal region of RAP74. Subunit of transcription initiation complex involved in initiation, elongation and promoter escape.Tetramer of 2 alpha and 2 beta TFIIF subunits interacts directly with RNA...; cl15395
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
K homology RNA-binding domain, type I.  KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that...; cd00105
Domain of unknown function (DUF1897); pfam09005
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Mitochondrial carrier protein; pfam00153
ADP/ATP transporter on adenylate translocase; Provisional
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Domain always found upstream of DENN domain, found in a variety of signalling proteins; smart00800
Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN; smart00799
dDENN domain; pfam03455
tubulin beta chain; Provisional
The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of...; cd02187
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cd00184
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cd00184
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cd00184
Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal...; cd00184
Alpha-2-macroglobulin MG1 domain; pfam11974
MG2 domain; pfam01835
Alpha-2-macroglobulin family N-terminal region; pfam07703
Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to...; cd00017
Alpha-2-macroglobulin family; pfam00207
Proteins similar to C3, C4 and C5 of vertebrate complement.  The vertebrate complement system, comprised of a large number of distinct plasma proteins, is an effector of both the acquired and innate immune systems. The point of convergence of the...; cd02896
A-macroglobulin complement component; pfam07678
A-macroglobulin receptor; pfam07677
NTR/C345C domain, complement C3 subfamily; The NTR domain found in complement C3 is also known as the C345C domain because it occurs at the C-terminus of complement C3, C4 and C5. Complement C3 plays a pivotal role in the activation of the complement...; cd03583
Lung seven transmembrane receptor; pfam06814
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Cdc42-Interacting Protein 4 and similar proteins; cd07653
Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of vertebrate Cdc42-Interacting Protein 4 and FormiN Binding Protein 1-Like; cd11628
Src Homology 3 domain superfamily; cl17036
Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3; cd10337
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cl02485
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
First Src homology 3 domain of VAV1 protein; cd11979
Src homology 2 (SH2) domain found in the Vav1 proteins; cd10405
C-terminal (or second) Src homology 3 domain of VAV1 protein; cd11976
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
First Src homology 3 domain of VAV1 protein; cd11979
Src homology 2 (SH2) domain found in the Vav1 proteins; cd10405
C-terminal (or second) Src homology 3 domain of VAV1 protein; cd11976
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology-like domain; cl00273
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
First Src homology 3 domain of VAV1 protein; cd11979
Src homology 2 (SH2) domain found in the Vav1 proteins; cd10405
C-terminal (or second) Src homology 3 domain of VAV1 protein; cd11976
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
C-terminal domain of methyl-CpG binding protein 2 and 3; pfam14048
C-terminal domain of methyl-CpG binding protein 2 and 3; pfam14048
C-terminal domain of methyl-CpG binding protein 2 and 3; pfam14048
C-terminal domain of methyl-CpG binding protein 2 and 3; pfam14048
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Receptor L domain; pfam01030
Furin-like cysteine rich region; pfam00757
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors; cd00064
Receptor L domain; pfam01030
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Catalytic domain of the Protein Tyrosine Kinase, Insulin Receptor; cd05061
Protein tyrosine kinase; pfam07714
Receptor L domain; pfam01030
Furin-like cysteine rich region; pfam00757
Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors; cd00064
Receptor L domain; pfam01030
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Catalytic domain of the Protein Tyrosine Kinase, Insulin Receptor; cd05061
Protein tyrosine kinase; pfam07714
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology (PH) domain; cd00821
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Pleckstrin homology (PH) domain; cd00821
Peroxisomal biogenesis factor 11 (PEX11); pfam05648
Peroxisomal biogenesis factor 11 (PEX11); pfam05648
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Polycystin cation channel; pfam08016
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
Patatin-like phospholipase domain containing protein 6 and protein 7; cd07225
Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; COG1752
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
Patatin-like phospholipase domain containing protein 6 and protein 7; cd07225
Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; COG1752
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
Patatin-like phospholipase domain containing protein 6 and protein 7; cd07225
Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; COG1752
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
Patatin-like phospholipase domain containing protein 6 and protein 7; cd07225
Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; COG1752
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; COG0664
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; cd00038
Patatin-like phospholipase domain containing protein 6 and protein 7; cd07225
Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; COG1752
CAMSAP CH domain; pfam11971
Microtubule-binding calmodulin-regulated spectrin-associated; smart01051
CAMSAP CH domain; pfam11971
Microtubule-binding calmodulin-regulated spectrin-associated; smart01051
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
type IV pilus biogenesis/stability protein PilW; TIGR02521
Uncharacterized conserved protein (DUF2346); pfam09803
GoLoco motif; pfam02188
LGN motif, putative GEFs specific for G-alpha GTPases; smart00390
Sec1 family; pfam00995
Sec1 family; pfam00995
Resistin; pfam06954
Resistin; pfam06954
Transport protein particle (TRAPP) component; pfam04051
Transport protein particle (TRAPP) component; pfam04051
Transport protein particle (TRAPP) component; pfam04051
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
4.5 repeats
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
7.5 repeats
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
7.5 repeats
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
1.5 repeats
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
4.5 repeats
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
Pilus assembly protein, PilO; cl01234
7.5 repeats
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
Pilus assembly protein, PilO; cl01234
7.5 repeats
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
Pilus assembly protein, PilO; cl01234
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
5.5 repeats
Pilus assembly protein, PilO; cl01234
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
Pilus assembly protein, PilO; cl01234
6.5 repeats
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
2.5 repeats
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
5.5 repeats
Protein of unknown function (DUF972); pfam06156
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
Pilus assembly protein, PilO; cl01234
6.5 repeats
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
6.5 repeats
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
3.5 repeats
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
7.5 repeats
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
Protein of unknown function (DUF2968); pfam11180
Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs; smart00164
Leucine-rich repeat containing protein 8; pfam12534
Leucine-rich repeat containing protein 8; pfam12534
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeat containing protein 8; pfam12534
Leucine-rich repeat containing protein 8; pfam12534
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Catalytic domain of the dual-specificity Protein Kinase, MAP kinase kinase 7; cd06618
Serine/Threonine protein kinases, catalytic domain; smart00220
Zona pellucida-like domain; cl02523
Small nuclear RNA activating complex subunit 2-like; pfam11035
Cortexin of kidney; pfam11057
mitochondrial import inner membrane, translocase subunit; TIGR00984
Tim44-like domain; pfam04280
ELAV/HuD family splicing factor; TIGR01661
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Chemokine_CC_DCCL:  subgroup of the Chemokine_CC subgroup based on the presence of a DCCL motif involving the two N-terminal cysteine residues; includes a number of small inducible cytokines capable of reversibly inhibiting normal hematopoietic...; cd01119
Chemokine_CC_DCCL:  subgroup of the Chemokine_CC subgroup based on the presence of a DCCL motif involving the two N-terminal cysteine residues; includes a number of small inducible cytokines capable of reversibly inhibiting normal hematopoietic...; cd01119
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
TB domain; pfam00683
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF domain; pfam07645
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain; smart00179
TB domain; pfam00683
Calcium-binding EGF domain; pfam07645
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Complement Clr-like EGF-like; pfam12662
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
EGF domain; pfam12947
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain; smart00179
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain; smart00179
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF domain; pfam07645
Calcium-binding EGF-like domain; smart00179
Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; cl00057
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
TRAM, LAG1 and CLN8 homology domains; smart00724
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a); pfam07347
S1_S28E: S28E, S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. S28E protein is a component of the 30S ribosomal subunit. S28E is highly conserved among archaea and eukaryotes. S28E may...; cd04457
KN motif; pfam12075
Ankyrin repeats (many copies); pfam13857
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
Rab GTPase; Provisional
Rab GTPase family 11 (Rab11)-like includes Rab11a, Rab11b, and Rab25; cd01868
The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins; smart00744
Vpu protein; pfam00558
The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins; smart00744
Vpu protein; pfam00558
The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins; smart00744
Heterogeneous nuclear ribonucleoprotein M; pfam11532
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Heterogeneous nuclear ribonucleoprotein M; pfam11532
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Src Homology 3 domain superfamily; cl17036
Myosin. Large ATPases; smart00242
Myosin motor domain, type I myosins. Myosin I generates movement at the leading edge in cell motility, and class I myosins have been implicated in phagocytosis and vesicle transport. Myosin I, an unconventional myosin, does not form dimers. This...; cd01378
Myosin tail; pfam06017
Src homology 3 domain of Myosins Ie, If, and similar proteins; cd11827
Reprolysin family propeptide; pfam01562
Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that...; cd04273
Thrombospondin type 1 repeats; smart00209
ADAM-TS Spacer 1; pfam05986
Thrombospondin type 1 domain; cl15278
Thrombospondin type 1 domain; cl15278
Thrombospondin type 1 repeats; smart00209
PLAC (protease and lacunin) domain; pfam08686
Actin; smart00268
Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cd00012
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
C-terminal domain of methyl-CpG binding protein 2 and 3; pfam14048
protein contains 156 amino acid repeat units
SEA domain; pfam01390
SEA domain; pfam01390
SEA domain; pfam01390
SEA domain; pfam01390
SEA domain; pfam01390
SEA domain; pfam01390
SEA domain; pfam01390
SEA domain; pfam01390
SEA domain; pfam01390
SEA domain; pfam01390
SEA domain; pfam01390
SEA domain; pfam01390
SEA domain; pfam01390
SEA domain; pfam01390
SEA domain; cl02507
SEA domain; pfam01390
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
F-box-like; pfam12937
Antagonist of mitotic exit network protein 1; cl15308
UBL5 ubiquitin-like modifier; cd01791
UBL5 ubiquitin-like modifier; cd01791
Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other...; cd00201
PPIC-type PPIASE domain; cl08278
Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; COG0760
Neurogenesis glycoprotein; pfam12308
Olfactomedin-like domain; pfam02191
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; cl00102
Collagen triple helix repeat (20 copies); pfam01391
Fibrillar collagen C-terminal domain; pfam01410
short chain dehydrogenase; Provisional
human estrogenic 17beta-hydroxysteroid dehydrogenase type 1 (type 1 17beta-HSD)-like, classical (c) SDRs; cd09806
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular...; cd00087
Brix domain; pfam04427
7 transmembrane receptor (rhodopsin family); pfam00001
Brix domain; pfam04427
Brix domain; pfam04427
7 transmembrane receptor (rhodopsin family); pfam00001
Eukaryotic translation initiation factor 3 subunit G; pfam12353
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
DMAP1-binding Domain; pfam06464
Cytosine specific DNA methyltransferase replication foci domain; pfam12047
CXXC zinc finger domain; pfam02008
BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG...; cd04760
BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG...; cd04711
Site-specific DNA methylase [DNA replication, recombination, and repair]; COG0270
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
DMAP1-binding Domain; pfam06464
Cytosine specific DNA methyltransferase replication foci domain; pfam12047
CXXC zinc finger domain; pfam02008
BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG...; cd04760
BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG...; cd04711
Site-specific DNA methylase [DNA replication, recombination, and repair]; COG0270
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cl16911
7 transmembrane receptor (rhodopsin family); pfam00001
Ribosomal protein L4/L1 family; pfam00573
Ribosomal protein L4/L1 family; pfam00573
Ribosomal protein L4/L1 family; pfam00573
Intercellular adhesion molecule (ICAM), N-terminal domain; pfam03921
Second immunoglobulin (Ig)-like domain of intercellular cell adhesion molecule-1 (ICAM-1, CD54) and similar proteins; cd05755
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13895
Intercellular adhesion molecule (ICAM), N-terminal domain; pfam03921
Intercellular adhesion molecule (ICAM), N-terminal domain; pfam03921
Immunoglobulin domain; cl11960
Intercellular adhesion molecule (ICAM), N-terminal domain; pfam03921
Immunoglobulin domain; cl11960
Intercellular adhesion molecule (ICAM), N-terminal domain; pfam03921
Second immunoglobulin (Ig)-like domain of intercellular cell adhesion molecule-1 (ICAM-1, CD54) and similar proteins; cd05755
Immunoglobulin domain; pfam13895
Immunoglobulin like; smart00410
Immunoglobulin like; smart00410
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C; cd00202
2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; cd00207
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Intercellular adhesion molecule (ICAM), N-terminal domain; pfam03921
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Band 4.1 homologues; smart00295
Src homology 2 (SH2) domain; cl15255
Protein tyrosine kinase; pfam07714
Pseudokinase (repeat 1) domain of the Protein Tyrosine Kinase, Tyrosine kinase 2; cd05076
Catalytic (repeat 2) domain of the Protein Tyrosine Kinase, Tyrosine kinase 2; cd05080
Tyrosine kinase, catalytic domain; smart00219
Cdc37 N terminal kinase binding; smart01071
Cdc37 Hsp90 binding domain; smart01070
Cdc37 C terminal domain; pfam08564
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch domain; smart00612
Kelch domain; smart00612
Kelch domain; smart00612
Kelch domain; smart00612
Kelch domain; smart00612
Kelch domain; smart00612
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch domain; smart00612
Kelch domain; smart00612
Kelch domain; smart00612
Kelch domain; smart00612
Kelch domain; smart00612
Kelch domain; smart00612
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
Peptidase family C54; pfam03416
KRI1-like family; pfam05178
KRI1-like family C-terminal; pfam12936
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Clathrin adaptor complex small chain; cl02092
C-terminal domain of medium Mu1B subunit in epithelial cell-specific clathrin-associated adaptor protein (AP) complex AP-1; cd09259
Adaptor complexes medium subunit family; pfam00928
Plasma-membrane choline transporter; pfam04515
Plasma-membrane choline transporter; pfam04515
domain in DSRM or ZnF_C2H2 domain containing proteins; smart00572
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
domain in DSRM or ZnF_C2H2 domain containing proteins; smart00572
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
domain in DSRM or ZnF_C2H2 domain containing proteins; smart00572
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
domain in DSRM or ZnF_C2H2 domain containing proteins; smart00572
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
domain in DSRM or ZnF_C2H2 domain containing proteins; smart00572
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; cd00048
Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; COG0343
queuine tRNA-ribosyltransferase; Provisional; cl00409
Dynamin_like protein family includes dynamins and Mx proteins; cd08771
Dynamin family; pfam00350
Dynamin central region; pfam01031
Dynamin pleckstrin homology (PH) domain; cd01256
Dynamin GTPase effector domain; pfam02212
Dynamin_like protein family includes dynamins and Mx proteins; cd08771
Dynamin family; pfam00350
Dynamin central region; pfam01031
Dynamin pleckstrin homology (PH) domain; cd01256
Dynamin GTPase effector domain; pfam02212
Dynamin_like protein family includes dynamins and Mx proteins; cd08771
Dynamin family; pfam00350
Dynamin central region; pfam01031
Dynamin pleckstrin homology (PH) domain; cd01256
Dynamin GTPase effector domain; pfam02212
Dynamin_like protein family includes dynamins and Mx proteins; cd08771
Dynamin family; pfam00350
Dynamin central region; pfam01031
Dynamin pleckstrin homology (PH) domain; cd01256
Dynamin GTPase effector domain; pfam02212
Dynamin_like protein family includes dynamins and Mx proteins; cd08771
Dynamin family; pfam00350
Dynamin central region; pfam01031
Dynamin pleckstrin homology (PH) domain; cd01256
Dynamin GTPase effector domain; pfam02212
emp24/gp25L/p24 family/GOLD; pfam01105
Immunoglobulin domain; cl11960
Coactivator-associated arginine methyltransferase 1 N terminal; pfam11531
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); cd02440
Yip1 domain; pfam04893
Uncharacterized conserved protein (DUF2366); pfam10171
QLQ; pfam08880
domain in helicases and associated with SANT domains; smart00573
domain in transcription and CHROMO domain helicases; smart00592
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone...; cd05516
QLQ; pfam08880
domain in helicases and associated with SANT domains; smart00573
domain in transcription and CHROMO domain helicases; smart00592
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone...; cd05516
QLQ; pfam08880
domain in helicases and associated with SANT domains; smart00573
domain in transcription and CHROMO domain helicases; smart00592
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone...; cd05516
QLQ; pfam08880
domain in helicases and associated with SANT domains; smart00573
domain in transcription and CHROMO domain helicases; smart00592
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone...; cd05516
QLQ; pfam08880
domain in helicases and associated with SANT domains; smart00573
domain in transcription and CHROMO domain helicases; smart00592
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone...; cd05516
QLQ; pfam08880
domain in helicases and associated with SANT domains; smart00573
domain in transcription and CHROMO domain helicases; smart00592
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone...; cd05516
QLQ; pfam08880
domain in helicases and associated with SANT domains; smart00573
domain in transcription and CHROMO domain helicases; smart00592
SNF2 family N-terminal domain; pfam00176
DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; cd00046
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone...; cd05516
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Low-density lipoprotein receptor repeat class B; cl10508
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Low-density lipoprotein receptor repeat class B; cl10508
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Low-density lipoprotein receptor repeat class B; cl10508
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Low-density lipoprotein receptor repeat class B; cl10508
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Low-density lipoprotein receptor repeat class B; cl10508
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Low-density lipoprotein receptor repeat class B; cl10508
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein receptor repeat class B; pfam00058
Low-density lipoprotein-receptor YWTD domain; smart00135
Low-density lipoprotein receptor repeat class B; pfam00058
Spc24 subunit of Ndc80; pfam08286
KN motif; pfam12075
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
KN motif; pfam12075
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Domain of unknown function (DUF3398); pfam11878
C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins; cd08696
Dock Homology Region 2, a GEF domain, of Class C Dedicator of Cytokinesis 6; cd11702
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), uroplakin_I_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment...; cd03156
Rab GTPase family 3 contains Rab3A, Rab3B, Rab3C and Rab3D; cd01865
Domain of unknown function (DUF4149); pfam13664
Domain of unknown function (DUF4149); pfam13664
Domain of unknown function (DUF4149); pfam13664
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the...; cd03384
Erythropoietin receptor, ligand binding; pfam09067
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
Ubiquitin domain of  RalGDS-like factor (RLF) and related proteins; cd00153
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
Ubiquitin domain of  RalGDS-like factor (RLF) and related proteins; cd00153
Chromosome segregation ATPases [Cell division and chromosome partitioning]; COG1196
Glucosidase II beta subunit-like; pfam12999
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cl00104
Glucosidase II beta subunit-like protein; cl06793
Glucosidase II beta subunit-like; pfam12999
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cl00104
Glucosidase II beta subunit-like protein; cl06793
ELAV/HuD family splicing factor; TIGR01661
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
ELAV/HuD family splicing factor; TIGR01661
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Evolutionarily conserved signalling intermediate in Toll pathway; pfam06239
Evolutionarily conserved signalling intermediate in Toll pathway; pfam06239
Evolutionarily conserved signalling intermediate in Toll pathway; pfam06239
Evolutionarily conserved signalling intermediate in Toll pathway; pfam06239
Calponin [Cytoskeleton]; COG5199
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin family repeat; pfam00402
Calponin family repeat; pfam00402
Calponin family repeat; pfam00402
Transcription elongation factor Elf1 like; pfam05129
Homo sapiens acid phosphatase 5 and related proteins, metallophosphatase domain; cd07378
Calcineurin-like phosphoesterase; pfam00149
Homo sapiens acid phosphatase 5 and related proteins, metallophosphatase domain; cd07378
Calcineurin-like phosphoesterase; pfam00149
Homo sapiens acid phosphatase 5 and related proteins, metallophosphatase domain; cd07378
Calcineurin-like phosphoesterase; pfam00149
Homo sapiens acid phosphatase 5 and related proteins, metallophosphatase domain; cd07378
Calcineurin-like phosphoesterase; pfam00149
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
C2H2-type zinc finger; pfam13912
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
alpha-mannosidase
N-terminal catalytic domain of lysosomal alpha-mannosidase and similar proteins; glycoside hydrolase family 38 (GH38); cd10810
Alpha mannosidase, middle domain; smart00872
alpha-mannosidase
N-terminal catalytic domain of lysosomal alpha-mannosidase and similar proteins; glycoside hydrolase family 38 (GH38); cd10810
Alpha mannosidase, middle domain; smart00872
Uncharacterized protein family (UPF0139); pfam03669
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
Deoxyhypusine synthase; cl00826
Deoxyhypusine synthase; pfam01916
Deoxyhypusine synthase; pfam01916
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
Importin-beta N-terminal domain; pfam03810
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
HEAT-like repeat; pfam13513
HEAT-like repeat; pfam13513
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Importin-beta N-terminal domain; pfam03810
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
HEAT-like repeat; pfam13513
HEAT-like repeat; pfam13513
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Importin-beta N-terminal domain; pfam03810
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
HEAT-like repeat; pfam13513
HEAT-like repeat; pfam13513
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Anion-transporting ATPase; pfam02374
ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; cd02035
Bestrophin, RFP-TM, chloride channel; pfam01062
HOOK protein; pfam05622
HOOK protein; pfam05622
Jun-like transcription factor; pfam03957
bZIP transcription factor; pfam00170
tryparedoxin peroxidase; Provisional
Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; cd03015
Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; COG0450
Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; cd03015
Mammalian RNase HII is functional when it forms a complex with two other accessory protein; cd07181
Folate receptor family; pfam03024
Folate receptor family; pfam03024
Folate receptor family; pfam03024
Folate receptor family; pfam03024
Folate receptor family; pfam03024
Folate receptor family; pfam03024
Folate receptor family; pfam03024
Folate receptor family; pfam03024
Putative binding domain; pfam13900
Domain of unknown function (DUF1908); pfam08926
Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase; cd05609
Serine/Threonine protein kinases, catalytic domain; smart00220
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Deoxyribonuclease II; pfam03265
Catalytic domain, repeat 1, of Deoxyribonuclease II alpha and similar proteins; cd09189
Catalytic domain, repeat 2, of Deoxyribonuclease II alpha and similar proteins; cd09191
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Glutaryl-CoA dehydrogenase; cd01151
Acyl-CoA dehydrogenases [Lipid metabolism]; COG1960
Glutaryl-CoA dehydrogenase; cd01151
acyl-coenzyme A oxidase
phenylalanyl-tRNA synthetase alpha chain; Provisional
Helix-turn-helix domains; cl00088
Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; cd00496
Calreticulin family; pfam00262
UV excision repair protein Rad23; TIGR00601
Ubiquitin-like domain of RAD23; cd01805
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
XPC-binding domain; pfam09280
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Ubiquitin-like domain of RAD23; cd01805
Ubiquitin homologues; smart00213
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
XPC-binding domain; cl15287
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
UV excision repair protein Rad23; TIGR00601
Ubiquitin-like domain of RAD23; cd01805
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
XPC-binding domain; pfam09280
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Growth arrest and DNA-damage-inducible proteins-interacting protein 1; pfam10147
Glycoprotein hormone beta chain homologues; cl00070
Nuclear factor I protein pre-N-terminus; pfam10524
N-terminal Mad Homology 1 (MH1) domain; cl00055
CTF/NF-I family transcription modulation region; pfam00859
Nuclear factor I protein pre-N-terminus; pfam10524
N-terminal Mad Homology 1 (MH1) domain; cl00055
CTF/NF-I family transcription modulation region; pfam00859
Nuclear factor I protein pre-N-terminus; pfam10524
N-terminal Mad Homology 1 (MH1) domain; cl00055
CTF/NF-I family transcription modulation region; pfam00859
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
N2,N2-dimethylguanosine tRNA methyltransferase; pfam02005
Methyltransferase domain; pfam13659
zinc finger; smart00356
N2,N2-dimethylguanosine tRNA methyltransferase; pfam02005
Methyltransferase domain; pfam13659
zinc finger; smart00356
N2,N2-dimethylguanosine tRNA methyltransferase; pfam02005
Methyltransferase domain; pfam13659
zinc finger; smart00356
BTB/POZ domain; pfam00651
The BEN domain is found in diverse animal proteins; smart01025
Syntaxin 6, N-terminal; pfam09177
Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in...; cd00193
Immediate early response protein (IER); pfam05760
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Voltage gated calcium channel IQ domain; pfam08763
13Q repeat
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Voltage gated calcium channel IQ domain; pfam08763
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Ion transport protein; pfam00520
Polycystin cation channel; pfam08016
Voltage gated calcium channel IQ domain; pfam08763
Family of unknown function (DUF572); pfam04502
Uncharacterized conserved protein [Function unknown]
methylthioribose-1-phosphate isomerase; Reviewed; PRK05720
S-methyl-5-thioribose-1-phosphate isomerase; TIGR00512
Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]; cl00348
Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]; cl00348
Protein of unknown function (DUF2462); pfam09495
Nanos RNA binding domain; pfam05741
Repeats in fly CG4713, worm Y37H9A.3 and human FLJ20241; smart00685
Repeats in fly CG4713, worm Y37H9A.3 and human FLJ20241; smart00685
Repeats in fly CG4713, worm Y37H9A.3 and human FLJ20241; smart00685
Repeats in fly CG4713, worm Y37H9A.3 and human FLJ20241; smart00685
C2 domain found in 5' repressor element under dual repression binding protein-1 (Freud-1); cd08690
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cl15309
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
RFX1 transcription activation region; pfam04589
RFX DNA-binding domain; pfam02257
IlGF_like family, relaxin_like subgroup, specific to vertebrates. Members include a number of active peptides including (pro)relaxin, mammalian Leydig cell-specific insulin-like peptide (gene INSL3), early placenta insulin-like peptide (ELIP; gene INSL4); cd04365
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; smart00060
SAM domain of Atherin/Atherin-like subfamily; cd09583
Sterile alpha motif; smart00454
cAMP-dependent protein kinase catalytic subunit; Provisional
Catalytic domain of the Protein Serine/Threonine Kinase, cAMP-dependent protein kinase; cd05580
cAMP-dependent protein kinase catalytic subunit; Provisional
Catalytic domain of the Protein Serine/Threonine Kinase, cAMP-dependent protein kinase; cd05580
ASF1 like histone chaperone; pfam04729
Galactose binding lectin domain; pfam02140
Olfactomedin-like domain; pfam02191
Domain present in hormone receptors; smart00008
Domain of unknown function (DUF3497); pfam12003
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
Latrophilin Cytoplasmic C-terminal region; pfam02354
Galactose binding lectin domain; pfam02140
Olfactomedin-like domain; pfam02191
Domain present in hormone receptors; smart00008
Domain of unknown function (DUF3497); pfam12003
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
Latrophilin Cytoplasmic C-terminal region; pfam02354
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); pfam00002
ABC-2 family transporter protein; pfam12730
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); pfam00002
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); pfam00002
helicase 45; Provisional
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N1; cd11630
Third Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N1; cd11636
C2 domain in Protein kinase C-like (PKN) proteins; cd08687
Catalytic domain of the Protein Serine/Threonine Kinase, Protein Kinase N; cd05589
Serine/Threonine protein kinases, catalytic domain; smart00220
Second Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Protein Kinase N1; cd11630
Protein kinase C-related kinase homology region 1 (HR1) domain that binds Rho family small GTPases; cl00087
C2 domain in Protein kinase C-like (PKN) proteins; cd08687
Catalytic domain of the Protein Serine/Threonine Kinase, Protein Kinase N; cd05589
Serine/Threonine protein kinases, catalytic domain; smart00220
7 transmembrane receptor (rhodopsin family); pfam00001
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]; COG0484
DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; cd06257
C-terminal substrate binding domain of DnaJ and HSP40; cd10747
Ubiquitin-like domain of Tsc13; cd01801
enoyl-CoA reductase
Phospholipid methyltransferase; cl00763
NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7); pfam05676
C-type lectin-like domain (CTLD) of the type found in human dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) and the related receptor, DC-SIGN receptor (DC-SIGNR); cd03590
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Latrophilin/CL-1-like GPS domain; pfam01825
7 transmembrane receptor (Secretin family); pfam00002
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
7 transmembrane receptor (Secretin family); pfam00002
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
G-protein-coupled receptor proteolytic site domain; smart00303
7 transmembrane receptor (Secretin family); pfam00002
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Sodium:dicarboxylate symporter family; cl00573
Na+/H+-dicarboxylate symporters [Energy production and conversion]; COG1301
Sodium:dicarboxylate symporter family; pfam00375
Na+/H+-dicarboxylate symporters [Energy production and conversion]; COG1301
Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; cd00032
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
RhoGAP_SYD1: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in SYD-1_like proteins. Syd-1, first identified and best studied in C.elegans, has been shown to play an important role in neuronal development by specifying...; cd04379
GTPase-activator protein for Rho-like GTPases; smart00324
Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism]; COG0028
Pyrimidine (PYR) binding domain of POX and related proteins; cd07035
Thiamine pyrophosphate enzyme, central domain; pfam00205
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL...; cd02004
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Domain found in Notch and Lin-12; smart00004
Domain found in Notch and Lin-12; smart00004
LNR domain; pfam00066
NOTCH protein; pfam06816
NOTCH protein; pfam07684
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13857
Ankyrin repeats (3 copies); pfam12796
Domain of unknown function (DUF3454); pfam11936
Alpha/beta hydrolase family; pfam12697
Alpha/beta hydrolase family; pfam12697
Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino...; cd05497
Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino...; cd05498
Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino...; cd05497
Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino...; cd05498
A-kinase anchoring protein 95 (AKAP95); pfam04988
A-kinase anchoring protein 95 (AKAP95); pfam04988
Pleckstrin homology-like domain; cl00273
C2 domain; cl14603
The DAB2IP family of Ras GTPase-activating proteins includes DAB2IP, nGAP, and Syn GAP. Disabled 2 interactive protein, (DAB2IP; also known as ASK-interacting protein 1 (AIP1)), is a member of the GTPase-activating proteins, down-regulates Ras-mediated...; cd05136
TATA element modulatory factor 1 DNA binding; pfam12329
Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; cd06583
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; COG2124
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; COG2124
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; COG2124
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; COG2124
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; COG2124
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; COG2124
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; COG2124
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; COG2124
7 transmembrane receptor (rhodopsin family); pfam00001
Olfactory receptor; pfam13853
Tropomyosin; pfam00261
Tropomyosin; pfam00261
Rab family protein; Provisional
Rab GTPase families 8, 10, 13 (Rab8, Rab10, Rab13); cd01867
Src homology 2 domain found in hematopoietic SH2 (HSH2) protein; cd09946
Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only]; COG5126
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
C-terminal domain of medium Mu1A subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-1; cd09258
Adaptor complexes medium subunit family; pfam00928
C-terminal domain of medium Mu1A subunit in ubiquitously expressed clathrin-associated adaptor protein (AP) complex AP-1; cd09258
Adaptor complexes medium subunit family; pfam00928
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Domain of unknown function (DUF4201); pfam13870
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Domain of unknown function (DUF4201); pfam13870
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Outer membrane protein (OmpH-like); smart00935
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Tropomyosin like; pfam12718
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Eps15 homology domain; smart00027
Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A...; cd00052
Outer membrane protein (OmpH-like); smart00935
Protein of unknown function (DUF1640); pfam07798
Tropomyosin like; pfam12718
Calreticulin family; pfam00262
Suppressor-of-White-APricot splicing regulator; smart00648
RNA polymerase II-binding domain; pfam04818
glycine rich nucleic binding domain; smart00443
Tpt phosphate/phosphoenolpyruvate translocator; TIGR00817
Triose-phosphate Transporter family; pfam03151
N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme; cd00183
TRIC channel; pfam05197
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
AAA domain; pfam13401
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Histone deacetylase complex, SIN3 component [Chromatin structure and dynamics]; COG5602
Paired amphipathic helix repeat; pfam02671
Paired amphipathic helix repeat; pfam02671
Paired amphipathic helix repeat; pfam02671
Sin3 family co-repressor; pfam08295
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
MG2 domain; pfam01835
Alpha-2-macroglobulin family N-terminal region; pfam07703
Alpha-2-macroglobulin family; pfam00207
Farnesoic acid 0-methyl transferase; pfam12248
Proteins similar to alpha2-macroglobulin (alpha (2)-M). This group also contains the pregnancy zone protein (PZP).  Alpha(2)-M and PZP are broadly specific proteinase inhibitors. Alpha (2)-M is a major carrier protein in serum. The structural thioester...; cd02897
A-macroglobulin complement component; pfam07678
A-macroglobulin receptor; pfam07677
Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; cd00104
ubitquitin-like domain of Myosin_IXb_RA; cd01779
Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; cl00286
Myosin. Large ATPases; smart00242
Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; cl00286
Calmodulin-binding motif; smart00015
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
RhoGAP_myosin_IXB: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in myosins IXB. Class IX myosins contain a characteristic head domain, a neck domain and a tail domain which contains a C6H2-zinc binding motif and a...; cd04407
GTPase-activator protein for Rho-like GTPases; smart00324
ubitquitin-like domain of Myosin_IXb_RA; cd01779
Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; cl00286
Myosin. Large ATPases; smart00242
Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; cl00286
Calmodulin-binding motif; smart00015
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
RhoGAP_myosin_IXB: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in myosins IXB. Class IX myosins contain a characteristic head domain, a neck domain and a tail domain which contains a C6H2-zinc binding motif and a...; cd04407
GTPase-activator protein for Rho-like GTPases; smart00324
Membrane fusion protein Use1; pfam09753
Occludin homology domain; pfam07303
DNA-binding domain of chicken ovalbumin upstream promoter transcription factors (COUP-TFs) is composed of two C4-type zinc fingers; cd06958
Ligand binding domain of chicken ovalbumin upstream promoter transcription factors, a member of the nuclear receptor family; cd06948
PDZ domain of MCC-2 bdg protein for Usher syndrome; pfam10506
VWFA-related Acidobacterial domain; TIGR03436
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
LEM domain; cl02649
GIY-YIG domain of hypothetical proteins from Metazoa; cd10454
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
Alpha/beta hydrolase family; pfam12697
Ribosomal protein L34; pfam00468
Det1 complexing ubiquitin ligase; pfam10172
Calcium-activated chloride channel; pfam04547
Calcium-activated chloride channel; pfam04547
tRNA modification GTPase TrmE; Reviewed; PRK05291
GTP-binding protein TrmE N-terminus; pfam10396
trmE is a tRNA modification GTPase; cd04164
Catalytic cysteine-containing C-terminus of GTPase, MnmE; pfam12631
tRNA modification GTPase TrmE; Reviewed; PRK05291
GTP-binding protein TrmE N-terminus; pfam10396
trmE is a tRNA modification GTPase; cd04164
Catalytic cysteine-containing C-terminus of GTPase, MnmE; pfam12631
tRNA modification GTPase TrmE; Reviewed; PRK05291
GTP-binding protein TrmE N-terminus; pfam10396
trmE is a tRNA modification GTPase; cd04164
Catalytic cysteine-containing C-terminus of GTPase, MnmE; pfam12631
tRNA modification GTPase TrmE; Reviewed; PRK05291
GTP-binding protein TrmE N-terminus; pfam10396
trmE is a tRNA modification GTPase; cd04164
Catalytic cysteine-containing C-terminus of GTPase, MnmE; pfam12631
PV-1 protein (PLVAP); pfam06637
chromosome segregation protein SMC, common bacterial type; TIGR02168
Protein of unknown function (DUF2464); pfam10240
Tryparedoxin (TryX)-like family, Rod-derived cone viability factor (RdCVF) subfamily; RdCVF is a thioredoxin (TRX)-like protein specifically expressed in photoreceptors. RdCVF was isolated and identified as a factor that supports cone survival in retinal...; cd03008
long-chain-acyl-CoA synthetase; Validated
AMP-binding enzyme; pfam00501
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; cd01400
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; cl11394
Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; cd06532
C2 domain first repeat in Munc13 (mammalian uncoordinated) proteins; cd08394
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
C2 domain second repeat in Munc13 (mammalian uncoordinated) proteins; cd04027
Domain of Unknown Function (DUF1041); pfam06292
Munc13 (mammalian uncoordinated) homology domain; pfam10540
C2 domain third repeat in Munc13 (mammalian uncoordinated) proteins; cd08395
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein; cd07674
mu-homology domain (MHD) of F-BAR domain-containing Fer/Cip4 homology domain-only protein 1 (FCH domain only 1 or FCHo1, also known as KIAA0290) and similar proteins; cd09268
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein; cd07674
mu-homology domain (MHD) of F-BAR domain-containing Fer/Cip4 homology domain-only protein 1 (FCH domain only 1 or FCHo1, also known as KIAA0290) and similar proteins; cd09268
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein; cd07674
C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD); cl10970
The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; cl12013
C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD); cl10970
Galactosyltransferase; cl09537
IlGF_like family, relaxin_like subgroup, specific to vertebrates. Members include a number of active peptides including (pro)relaxin, mammalian Leydig cell-specific insulin-like peptide (gene INSL3), early placenta insulin-like peptide (ELIP; gene INSL4); cd04365
IlGF_like family, relaxin_like subgroup, specific to vertebrates. Members include a number of active peptides including (pro)relaxin, mammalian Leydig cell-specific insulin-like peptide (gene INSL3), early placenta insulin-like peptide (ELIP; gene INSL4); cd04365
Band 4.1 homologues; smart00295
Src homology 2 (SH2) domain in the Janus kinase 3 (Jak3) proteins; cd10380
Protein tyrosine kinase; pfam07714
Pseudokinase (repeat 1) domain of the Protein Tyrosine Kinases, Janus kinases 2 and 3; cd05078
Catalytic (repeat 2) domain of the Protein Tyrosine Kinases, Janus kinases 2 and 3; cd05081
Protein tyrosine kinase; pfam07714
Ribosomal protein L20A (L18A) [Translation, ribosomal structure and biogenesis]; COG2157
Na(+)/iodide cotransporter NIS and related proteins; solute-binding domain; cd11503
Protein of unknown function (DUF1014); pfam06244
Protein of unknown function (DUF1014); pfam06244
Calcium-activated SK potassium channel; pfam03530
Ion channel; pfam07885
Calmodulin binding domain; smart01053
Arrestin (or S-antigen), N-terminal domain; pfam00339
Arrestin (or S-antigen), C-terminal domain; smart01017
Arrestin (or S-antigen), N-terminal domain; pfam00339
Arrestin (or S-antigen), C-terminal domain; smart01017
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Domain of unknown function (DUF1908); pfam08926
Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase; cd05609
Serine/Threonine protein kinases, catalytic domain; smart00220
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Src Homology 3 domain of the p85beta regulatory subunit of Class IA Phosphatidylinositol 3-kinases; cd11909
RhoGAP_p85: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in the p85 isoforms of the regulatory subunit of the class IA PI3K (phosphatidylinositol 3'-kinase). This domain is also called Bcr (breakpoint cluster region...; cd04388
GTPase-activator protein for Rho-like GTPases; smart00324
N-terminal Src homology 2 (nSH2) domain found in p85; cd09942
C-terminal Src homology 2 (cSH2) domain found in p85; cd09930
Gamma interferon inducible lysosomal thiol reductase (GILT); pfam03227
Mpv17 / PMP22 family; pfam04117
Rab family protein; Provisional
Rab GTPase family 3 contains Rab3A, Rab3B, Rab3C and Rab3D; cd01865
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
Metal dependent phosphohydrolases with conserved 'HD' motif; cd00077
IQ calmodulin-binding motif; cl15479
IQ calmodulin-binding motif; cl15479
IQ calmodulin-binding motif; cl15479
Jun-like transcription factor; pfam03957
bZIP transcription factor; pfam00170
Like-Sm protein 4; cd01723
Like-Sm protein 4; cd01723
Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; cd00501
Transforming growth factor-beta (TGF-beta) family; smart00204
Leucine rich repeat; pfam13855
Single-stranded DNA binding protein, SSDP; pfam04503
Single-stranded DNA binding protein, SSDP; pfam04503
Myo-inositol-1-phosphate synthase; cl00554
Myo-inositol-1-phosphate synthase; cl00554
Myo-inositol-1-phosphate synthase; cl00554
RNA polymerase II elongation factor ELL; pfam10390
Occludin homology domain; pfam07303
FKBP-type peptidyl-prolyl cis-trans isomerase; pfam00254
TPR repeat; pfam13414
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
TPR repeat; pfam13414
Uncharacterized conserved protein; pfam10241
Uncharacterized conserved protein; pfam10241
Uncharacterized conserved protein; pfam10241
Ubiquitin; cd01803
Ubiquitin homologues; smart00213
Ribosomal L40e family; cl00671
Ubiquitin; cd01803
Ubiquitin homologues; smart00213
Ribosomal L40e family; cl00671
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Brain specific membrane anchored protein; pfam12280
BTB/POZ domain; pfam00651
kelch-like protein; Provisional
BTB And C-terminal Kelch; pfam07707
Kelch motif; pfam01344
Kelch motif; pfam01344
Kelch motif; pfam13964
Kelch motif; pfam01344
Kelch motif; pfam01344
Transducer of regulated CREB activity, N terminus; pfam12884
Transducer of regulated CREB activity middle domain; pfam12885
Transducer of regulated CREB activity, C terminus; pfam12886
Transducer of regulated CREB activity, N terminus; pfam12884
Transducer of regulated CREB activity middle domain; pfam12885
Transducer of regulated CREB activity, C terminus; pfam12886
Cartilage oligomeric matrix protein; pfam11598
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Thrombospondin type 3 repeat; pfam02412
Thrombospondin C-terminal region; pfam05735
Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]
AAA domain; pfam13086
AAA domain; pfam13087
TGF-beta propeptide; pfam00688
Transforming growth factor-beta (TGF-beta) family; smart00204
TRAM, LAG1 and CLN8 homology domains; smart00724
TRAM, LAG1 and CLN8 homology domains; smart00724
Coatomer epsilon subunit; pfam04733
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
Coatomer epsilon subunit; pfam04733
Coatomer epsilon subunit; pfam04733
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
ATP-dependent RNA helicase SrmB; Provisional
DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; cd00268
Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; cd00079
Terminase small subunit; cl01513
Pleckstrin homology-like domain; cl00273
Homer type EVH1 domain; cd01206
Homer type EVH1 domain; cd01206
Homer type EVH1 domain; cd01206
Surp module; pfam01805
Surp module; pfam01805
glycine rich nucleic binding domain; smart00443
Surp module; pfam01805
Surp module; pfam01805
glycine rich nucleic binding domain; smart00443
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; cd00020
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Mitochondrial carrier protein; pfam00153
Predicted transmembrane protein 161AB; pfam10268
Predicted transmembrane protein 161AB; pfam10268
Predicted transmembrane protein 161AB; pfam10268
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I...; cd00265
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I...; cd00265
Uncharacterized conserved protein; pfam10167
Uncharacterized conserved protein; pfam10167
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination; cl02148
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain of the chondroitin sulfate proteoglycan core protein (CSPG), neurocan; cd05902
Link_domain_CSPGs_modules_1_3; this extracellular link domain is found in the first and third link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan. In addition, it is found in the first link module of three other CSPGs:...; cd03517
Link_domain_CSPGs_modules_2_4; this link domain is found in the second and fourth link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan and, in the second link module of three other CSPGs: versican, neurocan, and brevican. The...; cd03520
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
C-type lectin (CTL)/C-type lectin-like (CTLD) domain; cl02432
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; cd00033
Immunoglobulin V-set domain; pfam07686
Immunoglobulin (Ig)-like domain of human cartilage link protein (LP); cd05877
The link domain is a hyaluronan (HA)-binding domain. It functions to mediate adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It is found in the CD44 receptor and in human TSG-6. TSG-6 is the protein product of the tumor...; cl02612
Link_domain_HAPLN_module_2; this link domain is found in the second link module of proteins similar to the vertebrate HAPLN (hyaluronan/HA and proteoglycan binding link) protein family which includes cartilage link protein. The link domain is a...; cd03519
Protein of unknown function (DUF2781); pfam10914
Surp module; pfam01805
Suppressor-of-White-APricot splicing regulator; smart00648
glycine rich nucleic binding domain; smart00443
Cohesin loading factor; pfam10345
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of Protein Kinases; cd00180
GRIM-19 protein; pfam06212
YjeF-related protein N-terminus; cl00318
YjeF-related protein N-terminus; cl00318
Mucin-2 protein WxxW repeating region; pfam13330
Carboxypeptidase regulatory-like domain; pfam13620
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Glycoprotein hormone beta chain homologues; cl00070
Cna protein B-type domain; pfam13715
PBC domain; pfam03792
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
7 transmembrane receptor (rhodopsin family); pfam00001
Fes/CIP4 homology domain; smart00055
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
RhoGAP_GMIP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of GMIP (Gem interacting protein). GMIP plays important roles in neurite growth and axonal guidance, and interacts with Gem, a member of the RGK subfamily of the Ras...; cd04408
GTPase-activator protein for Rho-like GTPases; smart00324
P-type ATPase of unknown pump specificity (type V); TIGR01657
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid Dehalogenase-like Hydrolases; cl11391
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
inner capsid protein lambda-1 or VP3; cd11674
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Ubiquinol-cytochrome c reductase 8 kDa, N-terminal; pfam09165
Ubiquinol cytochrome reductase transmembrane region; pfam02921
ubiquinol-cytochrome c reductase, iron-sulfur subunit; TIGR01416
Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including...; cd03470
Immunoglobulin V-set domain; pfam07686
Immunoglobulin like; smart00410
A domain found in a protein subunit of human RNase MRP and RNase P ribonucleoprotein complexes and archaeal proteins; smart00538
Pleckstrin homology-like domain; cl00273
FYVE zinc finger; pfam01363
FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; cd00065
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Cyclin, C-terminal domain; pfam02984
Prefoldin alpha subunit; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta...; cd00584
Prefoldin alpha subunit; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta...; cd00584
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Q-cell neuroblast polarisation; pfam10034
Q-cell neuroblast polarisation; pfam10034
Double-stranded DNA-binding domain; pfam01984
Vacuolar sorting protein 9 (VPS9) domain; pfam02204
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13637
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (many copies); pfam13857
Tudor domain; pfam00567
Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; cl02573
L-type amino acid transporter; TIGR00911
L-type amino acid transporter; TIGR00911
L-type amino acid transporter; TIGR00911
chromosome segregation protein SMC, common bacterial type; TIGR02168
Helix-hairpin-helix motif; pfam12826
Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of Rhophilin-2; cd11634
BRO1-like domain; smart01041
Protein-interacting Bro1-like domain of RhoA-binding protein Rhophilin-2; cd09249
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Protein of unknown function (DUF1604); pfam07713
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cd00200
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about...; cd00112
L-type amino acid transporter; TIGR00911
Spore germination protein; cl15802
Basic region leucine zipper; pfam07716
Basic region leucine zipper; pfam07716
Basic region leucine zipper; pfam07716
Aminopeptidase P, N-terminal domain; cl08433
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; cd01087
Aminopeptidase P, N-terminal domain; pfam05195
Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; COG0006
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; cd01087
Aminopeptidase P, N-terminal domain; pfam05195
proline aminopeptidase P II; Provisional
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; cd01087
Sulfotransferase family; pfam03567
Sulfotransferase family; pfam03567
Sulfotransferase family; pfam03567
BTB/POZ domain; cl02518
BTB/POZ domain; cl02518
BTB/POZ domain; cl02518
Like-Sm protein 14, N-terminal domain; cd01736
FDF domain; pfam09532
Like-Sm protein 14, N-terminal domain; cd01736
FDF domain; pfam09532
glucose-6-phosphate isomerase; Reviewed; PRK00179
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; cd05015
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; cd05016
glucose-6-phosphate isomerase; Reviewed; PRK00179
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; cd05015
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; cd05016
Programmed cell death protein 2, C-terminal putative domain; pfam04194
Ubiquitin activating enzyme (E1) subunit UBA2. UBA2 is part of the heterodimeric activating enzyme (E1), specific for the SUMO family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to...; cd01489
Rossmann-fold NAD(P)(+)-binding proteins; cl09931
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
The second LIM domain of Ajuba-like proteins; cd09355
LIM is a small protein-protein interaction domain, containing two zinc fingers; cl02475
Secretoglobins are relatively small, secreted, disulphide-bridged dimeric proteins with encoding genes sharing substantial sequence similarity. Their family subunits may be grouped into five subfamilies, A-E. Uteroglobin (subfamily A), which is identical...; cd00633
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
domain in glucosyltransferases, myotubularins and other putative membrane-associated proteins; smart00568
domain in glucosyltransferases, myotubularins and other putative membrane-associated proteins; smart00568
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Hepsin, SRCR; pfam09272
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
Hepsin, SRCR; pfam09272
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; cd00190
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
Leucine rich repeat; pfam13855
Leucine-rich repeats, typical (most populated) subfamily; cl15310
Leucine rich repeat C-terminal domain; smart00082
EPTP domain; pfam03736
EPTP domain; pfam03736
EPTP domain; pfam03736
EPTP domain; pfam03736
EPTP domain; pfam03736
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
ATP1G1/PLM/MAT8 family; pfam02038
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
bZIP transcription factor; cl02576
Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers; cd00083
bZIP transcription factor; cl02576
Hepcidin; pfam06446
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin like; smart00410
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin like; smart00410
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin Constant domain; cd00098
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin Constant domain; cd00098
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin Constant domain; cd00098
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
CD80-like C2-set immunoglobulin domain; pfam08205
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin C-2 Type; smart00408
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin domain; cd00096
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
7 transmembrane receptor (rhodopsin family); pfam00001
glyceraldehyde-3-phosphate dehydrogenase; Provisional
Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; pfam00044
Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; pfam02800
Predicted membrane protein (DUF2053); pfam09767
Predicted membrane protein (DUF2053); pfam09767
Predicted membrane protein (DUF2053); pfam09767
Gastric H+/K+-ATPase, N terminal domain; pfam09040
sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit; TIGR01106
Cation transporter/ATPase, N-terminus; smart00831
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid Dehalogenase-like Hydrolases; cl11391
Cation transporting ATPase, C-terminus; pfam00689
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Ets-domain; pfam00178
Cytochrome c oxidase subunit VIb. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; cd00926
Tetraspanin family; pfam00335
Tetraspanin, extracellular domain or large extracellular loop (LEL), uroplakin_I_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment...; cd03156
BTB/POZ domain; pfam00651
Zinc-finger double domain; pfam13465
CXXC zinc finger domain; pfam02008
PHD-finger; pfam00628
PHD-finger; pfam00628
PHD-finger; pfam00628
Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine; cl02556
PHD-like zinc-binding domain; pfam13771
F/Y-rich N-terminus; pfam05964
FY-rich domain, C-terminal region; smart00542
Proteins containing SET domain [General function prediction only]
SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; smart00317
Zinc finger C-x8-C-x5-C-x3-H type (and similar); pfam00642
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zinc finger C-x8-C-x5-C-x3-H type (and similar); cl11592
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Zinc finger C-x8-C-x5-C-x3-H type (and similar); cl11592
Presenilin enhancer-2 subunit of gamma secretase; pfam10251
Alpha-crystallin domain found in alphaA-crystallin (HspB4), alphaB-crystallin (HspB5), and the small heat shock protein (sHsp) HspB6, also known as Hsp20. sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress; cd06478
The phosphoinositide binding Phox Homology domain of Tc10/Cdc42 GTPase-activating protein; cd07299
Src homology 3 domain of Rho GTPase-activating proteins 32 and 33, and similar proteins; cd11835
RhoGAP_CdGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP...; cd04384
GTPase-activator protein for Rho-like GTPases; smart00324
The Phox Homology domain, a phosphoinositide binding module; cl02563
Src homology 3 domain of Rho GTPase-activating proteins 32 and 33, and similar proteins; cd11835
RhoGAP_CdGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP...; cd04384
GTPase-activator protein for Rho-like GTPases; smart00324
proline dehydrogenase
Immunoglobulin domain; cd00096
CD80-like C2-set immunoglobulin domain; pfam08205
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin domain; cd00096
Eighth immunoglobulin-like domain of nephrin; cd05773
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin; smart00409
Immunoglobulin domain; cl11960
Immunoglobulin like; smart00410
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin; smart00409
Immunoglobulin I-set domain; pfam07679
Second immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2); cd05759
Immunoglobulin I-set domain; pfam07679
Immunoglobulin I-set domain; pfam07679
Immunoglobulin like; smart00410
Fifth immunoglobulin (Ig)-like domain of Kirrel (kin of irregular chiasm-like) 3 (also known as Neph2) and similar proteins; cd05758
amyloid A4; smart00006
Amyloid A4 N-terminal heparin-binding; pfam02177
Copper-binding of amyloid precursor, CuBD; pfam12924
E2 domain of amyloid precursor protein; pfam12925
beta-amyloid precursor protein C-terminus; pfam10515
amyloid A4; smart00006
Amyloid A4 N-terminal heparin-binding; pfam02177
Copper-binding of amyloid precursor, CuBD; pfam12924
E2 domain of amyloid precursor protein; pfam12925
beta-amyloid precursor protein C-terminus; pfam10515
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeats (3 copies); pfam12796
Ankyrin repeat; pfam00023
DAP10 membrane protein; pfam07213
DAP10 membrane protein; pfam07213
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Complex1_LYR-like; pfam13232
Nuclear envelope localisation domain; pfam10541
2OG-Fe(II) oxygenase superfamily; cl15773
2OG-Fe(II) oxygenase superfamily; cl15773
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
CAP-Gly domain; pfam01302
CAP-Gly domain; pfam01302
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
CAP-Gly domain; pfam01302
CAP-Gly domain; pfam01302
THAP domain; pfam05485
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Zinc-finger double domain; pfam13465
DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS [Transcription]; COG1594
RNA polymerase subunit 9; smart00661
Transcription factor S-II (TFIIS); cl02609
Ubiquitin-like domain of Alp11 tubulin-folding cofactor B; cd01789
CAP-Gly domain; pfam01302
EF-hand domain pair; pfam13833
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13833
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Cytochrome c oxidase subunit VIIa. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; cd00928
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Putative binding domain; pfam13900
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
FOG: WD40 repeat [General function prediction only]
WD40 repeats; smart00320
Rap/ran-GAP; pfam02145
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Domain of unknown function (DUF3401); pfam11881
N-terminal domain of DPF2/REQ; pfam14051
PHD-finger; pfam00628
PHD-finger; pfam00628
N-terminal domain of DPF2/REQ; pfam14051
PHD-finger; pfam00628
PHD-finger; pfam00628
N-terminal domain of DPF2/REQ; pfam14051
PHD-finger; pfam00628
PHD-finger; pfam00628
PKC-activated protein phosphatase-1 inhibitor; pfam05361
PKC-activated protein phosphatase-1 inhibitor; pfam05361
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; cd00109
YIF1; pfam03878
YIF1; pfam03878
YIF1; pfam03878
YIF1; pfam03878
YIF1; pfam03878
YIF1; pfam03878
YIF1; pfam03878
Ion channel; pfam07885
Ion channel; pfam07885
COP9 signalosome, subunit CSN8; pfam10075
Pleckstrin homology-like domain; cl00273
Sprouty protein (Spry); pfam05210
Protein of unknown function (DUF2465); pfam10239
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cl02485
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
RasGEF domain; pfam00617
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
RasGEF domain; pfam00617
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately...; cd06224
Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking; cd00155
Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second...; cd00029
Inositol 1,4,5-trisphosphate/ryanodine receptor; pfam08709
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
MIR domain; pfam02815
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
RIH domain; pfam01365
SPRY domain; pfam00622
RyR domain; pfam02026
RyR domain; pfam02026
Domain in SPla and the RYanodine Receptor; smart00449
SPRY domain; pfam00622
RIH domain; pfam01365
RyR domain; pfam02026
RyR domain; pfam02026
RyR and IP3R Homology associated; pfam08454
EF-hand domain pair; pfam13833
Ryanodine Receptor TM 4-6; pfam06459
Ion transport protein; pfam00520
Inositol 1,4,5-trisphosphate/ryanodine receptor; pfam08709
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
MIR domain; pfam02815
Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; smart00472
RIH domain; pfam01365
SPRY domain; pfam00622
RyR domain; pfam02026
RyR domain; pfam02026
Domain in SPla and the RYanodine Receptor; smart00449
SPRY domain; pfam00622
RIH domain; pfam01365
RyR domain; pfam02026
RyR domain; pfam02026
RyR and IP3R Homology associated; pfam08454
EF-hand domain pair; pfam13833
Ryanodine Receptor TM 4-6; pfam06459
Ion transport protein; pfam00520
Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase-like Protein Serine/Threonine Kinases; cd06613
Serine/Threonine protein kinases, catalytic domain; smart00220
Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2; smart00036
Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase-like Protein Serine/Threonine Kinases; cd06613
Serine/Threonine protein kinases, catalytic domain; smart00220
Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2; smart00036
COP9 signalosome, subunit CSN8; pfam10075
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
EF-hand domain pair; pfam13499
Ca2+ insensitive EF hand; pfam08726
Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction; cd00044
Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are...; cd00214
EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to...; cd00051
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
enoyl-CoA hydratase; Provisional
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; cd06558
hnRNP-L/PTB/hephaestus splicing factor family; TIGR01649
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
hnRNP-L/PTB/hephaestus splicing factor family; TIGR01649
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Src homology 2 (SH2) domain; cl15255
Vacuolar sorting protein 9 (VPS9) domain; pfam02204
Vacuolar sorting protein 9 (VPS9) domain; pfam02204
SIRT1: Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2...; cd01408
SIRT1: Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2...; cd01408
SIRT1: Eukaryotic group (class1) which includes human sirtuins SIRT1-3 and yeast Hst1-4; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2...; cd01408
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (many copies); pfam13637
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
seryl-tRNA synthetase; Provisional
Seryl-tRNA synthetase N-terminal domain; pfam02403
Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme bound...; cd00770
seryl-tRNA synthetase; Provisional
Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme bound...; cd00770
S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; cd03368
S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; cd03368
S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; cd03368
F-box-like; pfam12937
F-box associated region; pfam04300
F-box-like; pfam12937
F-box associated region; pfam04300
F-box domain; cl02535
F-box associated region; pfam04300
purple acid phosphatases of the metallophosphatase superfamily, metallophosphatase domain; cd00839
Calcineurin-like phosphoesterase; pfam00149
PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the...; cd01093
Catalytic domain of the Protein Serine/Threonine Kinase, Group II p21-activated kinase; cd06648
Serine/Threonine protein kinases, catalytic domain; smart00220
PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the...; cd01093
Catalytic domain of the Protein Serine/Threonine Kinase, Group II p21-activated kinase; cd06648
Serine/Threonine protein kinases, catalytic domain; smart00220
PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the...; cd01093
Catalytic domain of the Protein Serine/Threonine Kinase, Group II p21-activated kinase; cd06648
Serine/Threonine protein kinases, catalytic domain; smart00220
PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the...; cd01093
Catalytic domain of the Protein Serine/Threonine Kinase, Group II p21-activated kinase; cd06648
Serine/Threonine protein kinases, catalytic domain; smart00220
PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the...; cd01093
Catalytic domain of the Protein Serine/Threonine Kinase, Group II p21-activated kinase; cd06648
Serine/Threonine protein kinases, catalytic domain; smart00220
F-box associated region; pfam04300
Leucine rich repeat; pfam13855
Leucine rich repeat; pfam13855
Leucine rich repeat C-terminal domain; smart00082
Immunoglobulin domain; cl11960
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
ADF-homology domain of glia maturation factor beta and related proteins; cd11283
SAM domain of Smaug subfamily; cd09557
SAM domain (Sterile alpha motif); pfam07647
Paf1; pfam03985
Paf1; pfam03985
Mediator complex subunit 29; pfam11568
Zinc finger C-x8-C-x5-C-x3-H type (and similar); pfam00642
Zinc finger C-x8-C-x5-C-x3-H type (and similar); pfam00642
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Clg (common-site lymphoma/leukemia guanine nucleotide exchange factor) pleckstrin homology (PH) domain; cd01222
40S ribosomal protein S16; Provisional
Spt5 transcription elongation factor, acidic N-terminal; pfam11942
transcription antitermination protein NusG; Validated; PRK08559
Eukaryotic N-Utilization Substance G (NusG) N-terminal (NGN) domain, including plant KTF1 (KOW domain-containing Transcription Factor 1); cd09888
KOW (Kyprides, Ouzounis, Woese) motif; smart00739
KOW motif; pfam00467
Spt5 C-terminal nonapeptide repeat binding Spt4; smart01104
Spt5 C-terminal nonapeptide repeat binding Spt4; pfam12815
DAZ associated protein 2 (DAZAP2); pfam11029
Spt5 transcription elongation factor, acidic N-terminal; pfam11942
transcription antitermination protein NusG; Validated; PRK08559
Eukaryotic N-Utilization Substance G (NusG) N-terminal (NGN) domain, including plant KTF1 (KOW domain-containing Transcription Factor 1); cd09888
KOW (Kyprides, Ouzounis, Woese) motif; smart00739
KOW motif; pfam00467
Spt5 C-terminal nonapeptide repeat binding Spt4; smart01104
Spt5 C-terminal nonapeptide repeat binding Spt4; pfam12815
DAZ associated protein 2 (DAZAP2); pfam11029
Spt5 transcription elongation factor, acidic N-terminal; pfam11942
transcription antitermination protein NusG; Validated; PRK08559
Eukaryotic N-Utilization Substance G (NusG) N-terminal (NGN) domain, including plant KTF1 (KOW domain-containing Transcription Factor 1); cd09888
KOW (Kyprides, Ouzounis, Woese) motif; smart00739
KOW motif; pfam00467
Spt5 C-terminal nonapeptide repeat binding Spt4; smart01104
Spt5 C-terminal nonapeptide repeat binding Spt4; pfam12815
DAZ associated protein 2 (DAZAP2); pfam11029
Spt5 transcription elongation factor, acidic N-terminal; pfam11942
transcription antitermination protein NusG; Validated; PRK08559
Eukaryotic N-Utilization Substance G (NusG) N-terminal (NGN) domain, including plant KTF1 (KOW domain-containing Transcription Factor 1); cd09888
KOW (Kyprides, Ouzounis, Woese) motif; smart00739
KOW motif; pfam00467
Spt5 C-terminal nonapeptide repeat binding Spt4; smart01104
Spt5 C-terminal nonapeptide repeat binding Spt4; pfam12815
DAZ associated protein 2 (DAZAP2); pfam11029
NLI interacting factor-like phosphatase; pfam03031
N terminus of Notch ligand; pfam07657
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
N terminus of Notch ligand; pfam07657
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
selT/selW/selH selenoprotein domain; TIGR02174
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may...; cd00070
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cl00084
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
cyclin-dependent protein kinase; Provisional
Protein Kinases, catalytic domain; cl09925
fibrillarin; Provisional
Fibrillarin-like rRNA methylase [Translation, ribosomal structure and biogenesis]; COG1889
von Willebrand factor type D domain; pfam00094
This domain contains 8 conserved cysteine residues; smart00832
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor type C domain; cl02515
von Willebrand factor (vWF) type D domain; smart00216
This domain contains 8 conserved cysteine residues; smart00832
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor type C domain; cl02515
von Willebrand factor (vWF) type D domain; smart00216
This domain contains 8 conserved cysteine residues; smart00832
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor type C domain; cl02515
von Willebrand factor type D domain; pfam00094
This domain contains 8 conserved cysteine residues; smart00832
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor type C domain; cl02515
von Willebrand factor type D domain; pfam00094
This domain contains 8 conserved cysteine residues; smart00832
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor type C domain; cl02515
von Willebrand factor (vWF) type D domain; smart00216
This domain contains 8 conserved cysteine residues; smart00832
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor type C domain; cl02515
von Willebrand factor type D domain; pfam00094
This domain contains 8 conserved cysteine residues; smart00832
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor type C domain; cl02515
von Willebrand factor type D domain; pfam00094
This domain contains 8 conserved cysteine residues; smart00832
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor type C domain; cl02515
von Willebrand factor (vWF) type D domain; smart00216
This domain contains 8 conserved cysteine residues; smart00832
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor type C domain; cl02515
von Willebrand factor type D domain; pfam00094
This domain contains 8 conserved cysteine residues; smart00832
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor type C domain; cl02515
von Willebrand factor type D domain; pfam00094
This domain contains 8 conserved cysteine residues; smart00832
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor type C domain; cl02515
von Willebrand factor (vWF) type D domain; smart00216
This domain contains 8 conserved cysteine residues; smart00832
Trypsin Inhibitor like cysteine rich domain; pfam01826
von Willebrand factor type D domain; pfam00094
26S protease regulatory subunit 6B-like protein; Provisional
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
26S proteasome subunit P45 family; TIGR01242
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Src Homology 3 domain of Mixed Lineage Kinases 1, 2, and 3; cd12059
Tyrosine kinase, catalytic domain; smart00219
Catalytic domain of Protein Tyrosine Kinases; cd00192
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cl02429
Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB...; cd00043
Akt pleckstrin homology (PH) domain; cd01241
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, Protein Kinase B; cd05571
Pleckstrin homology-like domain; cl00273
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, Protein Kinase B; cd05571
Pleckstrin homology-like domain; cl00273
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of the Protein Serine/Threonine Kinase, Protein Kinase B; cd05571
SAM domain of CS047 subfamily; cd09531
SAM domain of CS047 subfamily; cd09531
phospholipase-D-like protein; Provisional
Putative catalytic domain, repeat 1, of vertebrate phospholipase PLD3; cd09144
Putative catalytic domain, repeat 2, of vertebrate phospholipase PLD3; cd09147
phospholipase-D-like protein; Provisional
Putative catalytic domain, repeat 1, of vertebrate phospholipase PLD3; cd09144
Putative catalytic domain, repeat 2, of vertebrate phospholipase PLD3; cd09147
Protein Kinases, catalytic domain; cl09925
cyclin-dependent protein kinase; Provisional
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
Cornifin (SPRR) family; pfam02389
Cornifin (SPRR) family; pfam02389
Cornifin (SPRR) family; pfam02389
PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; cd00992
SERTA motif; pfam06031
SERTA motif; pfam06031
SERTA motif; pfam06031
biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; cd05244
NADH(P)-binding; pfam13460
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; cd00014
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cl02488
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Pleckstrin homology-like domain; cl00273
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; cd00176
K+ channel tetramerisation domain; pfam02214
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Complement Clr-like EGF-like; pfam12662
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain; smart00179
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
TB domain; pfam00683
Calcium-binding EGF-like domain; smart00179
Pleckstrin homology-like domain; cl00273
NUMB domain; pfam06311
Predicted unusual protein kinase [General function prediction only]; COG0661
ABC1 family; pfam03109
Protein Kinases, catalytic domain; cl09925
Predicted unusual protein kinase [General function prediction only]; COG0661
ABC1 family; pfam03109
Protein Kinases, catalytic domain; cl09925
Inositol polyphosphate kinase; pfam03770
RNA-binding proteins (RRM domain) [General function prediction only]
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
RRM (RNA recognition motif), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), is a highly abundant domain in eukaryotes found in proteins involved in post-transcriptional gene expression processes including mRNA and rRNA...; cd00590
Melanoma Inhibitory Activity protein; cd11890
Melanoma Inhibitory Activity protein; cd11890
Rab family protein; Provisional
Rab GTPase family 4 (Rab4); cd04113
start of isoform PHD1p43, PMID:16509823
start of isoform PHD1p40, PMID:16509823
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam13640
start of isoform PHD1p43, PMID:16509823
start of isoform PHD1p40, PMID:16509823
Prolyl 4-hydroxylase alpha subunit homologues; smart00702
2OG-Fe(II) oxygenase superfamily; pfam13640
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
cytochrome P450 83A1
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Cytochrome P450; pfam00067
Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; cl12078
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Second immunoglobulin (Ig)-like domain of Axl/Tyro3 receptor tyrosine kinases (RTKs); cd05749
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Catalytic domain of the Protein Tyrosine Kinase, Axl; cd05075
Protein kinase; unclassified specificity; smart00221
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Second immunoglobulin (Ig)-like domain of Axl/Tyro3 receptor tyrosine kinases (RTKs); cd05749
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; cd00063
Catalytic domain of the Protein Tyrosine Kinase, Axl; cd05075
Protein kinase; unclassified specificity; smart00221
SPRY domain; pfam00622
AAA domain; pfam13671
SPRY domain; pfam00622
AAA domain; pfam13671
Coiled-coil domain containing protein (DUF2052); pfam09747
Coiled-coil domain containing protein (DUF2052); pfam09747
TGF-beta propeptide; pfam00688
Transforming growth factor beta like domain; pfam00019
Ciliary basal body-associated, B9 protein; pfam07162
Interferon-induced transmembrane protein; pfam04505
Interferon-induced transmembrane protein; pfam04505
Interferon-induced transmembrane protein; pfam04505
Interferon-induced transmembrane protein; pfam04505
Interferon-induced transmembrane protein; pfam04505
Interferon-induced transmembrane protein; pfam04505
archaeal exosome-like complex exonuclease 1; TIGR02065
RRP46 subunit of eukaryotic exosome; cd11372
pyruvate dehydrogenase E1 component, alpha subunit; TIGR03181
Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; cd02000
pyruvate dehydrogenase E1 component, alpha subunit; TIGR03181
Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; cd02000
Galactosyltransferase; cl09537
Protein of unknown function (DUF3685); pfam12452
Protein of unknown function (DUF3685); pfam12452
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin V-set domain; pfam07686
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin V-set domain; pfam07686
Fourth immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05740
Immunoglobulin domain; cd00096
Fourth immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05740
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13895
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin V-set domain; pfam07686
u-PAR/Ly-6 domain; pfam00021
DM DNA binding domain; pfam00751
Ribosomal protein S19e; pfam01090
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cd00096
Immunoreceptor tyrosine-based activation motif; smart00077
Immunoreceptor tyrosine-based activation motif; pfam02189
Regulator of G protein signaling (RGS) domain found in the Rho guanine nucleotide exchange factor (GEF), p115 RhoGEF; cd08755
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Regulator of G protein signaling (RGS) domain found in the Rho guanine nucleotide exchange factor (GEF), p115 RhoGEF; cd08755
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
Regulator of G protein signaling (RGS) domain superfamily; cl02565
Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains; cd00160
PRA1 family protein; pfam03208
sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit; TIGR01106
Cation transporter/ATPase, N-terminus; smart00831
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid Dehalogenase-like Hydrolases; cl11391
Cation transporting ATPase, C-terminus; pfam00689
sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit; TIGR01106
Cation transporter/ATPase, N-terminus; smart00831
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid Dehalogenase-like Hydrolases; cl11391
Cation transporting ATPase, C-terminus; pfam00689
sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit; TIGR01106
Cation transporter/ATPase, N-terminus; smart00831
E1-E2 ATPase; pfam00122
Putative hydrolase of sodium-potassium ATPase alpha subunit; pfam13246
Haloacid Dehalogenase-like Hydrolases; cl11391
Cation transporting ATPase, C-terminus; pfam00689
N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the KA1 and KA2 subunits of Kainate receptor; cd06394
Receptor family ligand binding region; pfam01094
Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; cd00134
Ligand-gated ion channel; pfam00060
Eukaryotic homologues of bacterial periplasmic substrate binding proteins; smart00079
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Found in Pit-Oct-Unc transcription factors; smart00352
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Found in Pit-Oct-Unc transcription factors; smart00352
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Found in Pit-Oct-Unc transcription factors; smart00352
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Found in Pit-Oct-Unc transcription factors; smart00352
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
The Death Domain Superfamily of protein-protein interaction domains; cl14633
The Death Domain Superfamily of protein-protein interaction domains; cl14633
The Death Domain Superfamily of protein-protein interaction domains; cl14633
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Protein Kinases, catalytic domain; cl09925
Protein kinase domain; pfam00069
Ets-domain; pfam00178
Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]; COG5648
SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and...; cd01388
PAF_acetylhydrolase (PAF-AH)_like subfamily of SGNH-hydrolases. Platelet-activating factor (PAF) and PAF-AH are key players in inflammation and in atherosclerosis. PAF-AH is a calcium independent phospholipase A2 which exhibits strong substrate...; cd01820
PAF_acetylhydrolase (PAF-AH)_like subfamily of SGNH-hydrolases. Platelet-activating factor (PAF) and PAF-AH are key players in inflammation and in atherosclerosis. PAF-AH is a calcium independent phospholipase A2 which exhibits strong substrate...; cd01820
PAF_acetylhydrolase (PAF-AH)_like subfamily of SGNH-hydrolases. Platelet-activating factor (PAF) and PAF-AH are key players in inflammation and in atherosclerosis. PAF-AH is a calcium independent phospholipase A2 which exhibits strong substrate...; cd01820
Rhodopsin-like GPCR transmembrane domain; pfam10192
CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; cd00041
Galactose oxidase, central domain; pfam13415
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cd00054
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in...; cd00055
Laminin EGF-like (Domains III and V); pfam00053
Galactose oxidase, central domain; cl02701
Galactose oxidase, central domain; pfam13415
Galactose oxidase, central domain; cl02701
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the...; cl09941
uncharacterized Cys-rich domain; TIGR01571
Hormone-sensitive lipase (HSL) N-terminus; pfam06350
Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; cl12031
alpha/beta hydrolase fold; pfam07859
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Fourth immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05740
Immunoglobulin domain; pfam13895
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Fourth immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05740
Immunoglobulin domain; pfam13895
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Fourth immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05740
Immunoglobulin domain; pfam13895
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Fourth immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05740
Immunoglobulin domain; pfam13895
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Fourth immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05740
Immunoglobulin domain; pfam13895
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Fourth immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05740
Immunoglobulin domain; pfam13895
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13895
Immunoglobulin I-set domain; pfam07679
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13895
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13895
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
u-PAR/Ly-6 domain; pfam00021
u-PAR/Ly-6 domain; pfam00021
u-PAR/Ly-6 domain; pfam00021
u-PAR/Ly-6 domain; pfam00021
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
Pleckstrin homology (PH) domain; cd00821
Metallo-beta-lactamase superfamily; cl00446
Zn-dependent hydrolases, including glyoxylases [General function prediction only]; COG0491
XRCC1 N terminal domain; pfam01834
Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; cd00027
Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; cd00027
Phospholipase A2 inhibitor; pfam02988
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cl10471
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cl10471
Zinc finger, C2H2 type; cl15478
Zinc finger, C2H2 type; cl15478
U2 snRNP auxilliary factor, large subunit, splicing factor; TIGR01642
U2 snRNP auxilliary factor, large subunit, splicing factor; TIGR01642
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
putative band 4.1 homologues' binding motif; smart00294
u-PAR/Ly-6 domain; pfam00021
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
Ly-6 antigen / uPA receptor -like domain; smart00134
Ly-6 antigen / uPA receptor -like domain; smart00134
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cl10471
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
u-PAR/Ly-6 domain; pfam00021
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
P-loop containing Nucleoside Triphosphate Hydrolases; cl09099
Interferon-inducible GTPase (IIGP); pfam05049
p47 GTPase family includes IGTP, TGTP/Mg21, IRG-47, GTPI, LRG-47, and IIGP1; cd04104
Calcium-activated SK potassium channel; pfam03530
Ion channel; pfam07885
Calmodulin binding domain; pfam02888
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these...; cd00117
Putative binding domain; pfam13900
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
C2H2-type
Zinc-finger double domain; pfam13465
C2H2-type
C2H2-type
Zinc-finger double domain; pfam13465
C2H2-type
Zinc-finger double domain; pfam13465
C2H2-type
Zinc-finger double domain; pfam13465
C2H2-type
Zinc-finger double domain; pfam13465
C2H2-type
Zinc-finger double domain; pfam13465
C2H2-type
Zinc-finger double domain; pfam13465
C2H2-type
Zinc-finger double domain; pfam13465
C2H2-type
Zinc-finger double domain; pfam13465
C2H2-type
Zinc-finger double domain; pfam13465
C2H2-type
Zinc-finger double domain; pfam13465
C2H2-type
Zinc-finger double domain; pfam13465
C2H2-type
C2H2-type
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
krueppel associated box; smart00349
KRAB (Kruppel-associated box) domain -A box; cd07765
FOG: Zn-finger [General function prediction only]
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Zinc-finger double domain; pfam13465
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin domain; cl11960
Immunoglobulin domain; cd00096
Immunoglobulin domain; cl11960
First immunoglobulin (Ig) domain of poliovirus receptor (PVR, also known as CD155) and similar proteins; cd05718
Immunoglobulin V-Type; smart00406
Second immunoglobulin (Ig) domain of nectin-2 (also known as poliovirus receptor related protein 2 or CD112) and similar proteins; cd07703
Immunoglobulin domain; cl11960
First immunoglobulin (Ig) domain of poliovirus receptor (PVR, also known as CD155) and similar proteins; cd05718
Immunoglobulin V-Type; smart00406
Second immunoglobulin (Ig) domain of nectin-2 (also known as poliovirus receptor related protein 2 or CD112) and similar proteins; cd07703
Immunoglobulin domain; cl11960
First immunoglobulin (Ig) domain of poliovirus receptor (PVR, also known as CD155) and similar proteins; cd05718
Immunoglobulin V-Type; smart00406
Second immunoglobulin (Ig) domain of nectin-2 (also known as poliovirus receptor related protein 2 or CD112) and similar proteins; cd07703
Immunoglobulin domain; cl11960
First immunoglobulin (Ig) domain of poliovirus receptor (PVR, also known as CD155) and similar proteins; cd05718
Immunoglobulin V-Type; smart00406
Second immunoglobulin (Ig) domain of nectin-2 (also known as poliovirus receptor related protein 2 or CD112) and similar proteins; cd07703
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; pfam13895
First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM); cd05774
Immunoglobulin V-set domain; pfam07686
Ankyrin repeats (many copies); pfam13637
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
CBL proto-oncogene N-terminal domain 1; pfam02262
CBL proto-oncogene N-terminus, EF hand-like domain; pfam02761
Src homology 2 (SH2) domain found in the Cbl-b TKB domain; cd09920
Zinc finger, C3HC4 type (RING finger); pfam13923
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cd00162
CBL proto-oncogene N-terminal domain 1; pfam02262
CBL proto-oncogene N-terminus, EF hand-like domain; pfam02761
Src homology 2 (SH2) domain found in the Cbl-b TKB domain; cd09920
Zinc finger, C3HC4 type (RING finger); pfam13923
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
CD80-like C2-set immunoglobulin domain; pfam08205
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin C-2 Type; smart00408
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
CD80-like C2-set immunoglobulin domain; pfam08205
Immunoglobulin domain; cd00096
Immunoglobulin I-set domain; pfam07679
Immunoglobulin C-2 Type; smart00408
Immunoglobulin C-2 Type; smart00408
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Immunoglobulin V-set domain; pfam07686
Immunoglobulin domain; cl11960
Immunoglobulin domain; cl11960
Translocase of outer mitochondrial membrane 40 (Tom40); cd07305
Translocase of outer mitochondrial membrane 40 (Tom40); cd07305
Translocase of outer mitochondrial membrane 40 (Tom40); cd07305
Apolipoprotein A1/A4/E domain; pfam01442
Apolipoprotein C-I (ApoC-1); pfam04691
Apolipoprotein C-II; pfam05355
Cleft lip and palate transmembrane protein 1 (CLPTM1); pfam05602
N-terminal sub-domain of the Rel homology domain (RHD) of the reticuloendotheliosis viral oncogene homolog B (RelB) protein; cd07886
IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to...; cd01177
Alternative splicing regulator; pfam09750
Zinc-finger double domain; pfam13465
C2H2 type zinc-finger (2 copies); pfam12756
Zinc finger, C2H2 type; cl15478
Zinc-finger double domain; pfam13465
Gemin 7; cd11677
Gemin 7; cd11677
Gemin 7; cd11677
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; cd00116
Leucine rich repeat; pfam13855
KAP family P-loop domain; pfam07693
Transport protein particle (TRAPP) component; pfam04051
Transport protein particle (TRAPP) component; pfam04051
Exocyst complex component Sec6; pfam06046
Protein Kinases, catalytic domain; cl09925
Serine/Threonine protein kinases, catalytic domain; smart00220
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Kinase associated domain 1; pfam02149
Serine/Threonine protein kinases, catalytic domain; smart00220
Catalytic domain of AGC family Protein Serine/Threonine Kinases; cd05123
Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; cd00194
Phosphagen (guanidino) kinases such as creatine kinase and similar enzymes; cd00716
Rabaptin-like protein; pfam09311
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; cd00189
Tetratricopeptide repeat; pfam13424
DNA repair helicase (rad3); TIGR00604
DEAD_2; pfam06733
Protein of unknown function (DUF1227); pfam06777
helicase superfamily c-terminal domain; smart00491
DEAD-like helicases superfamily; smart00488
DEAD_2; pfam06733
Protein of unknown function (DUF1227); pfam06777
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Src Homology 3 (SH3) domain of Inhibitor of ASPP protein (iASPP); cd11952
ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; cd00204
Ankyrin repeats (3 copies); pfam12796
Src Homology 3 (SH3) domain of Inhibitor of ASPP protein (iASPP); cd11952
DNA-directed RNA polymerase I subunit RPA34.5; pfam08208
DNA repair protein rad10; TIGR00597
Helix-hairpin-helix motif; pfam00633
DNA repair protein rad10; TIGR00597
Helix-hairpin-helix motif; pfam00633
DNA repair protein rad10; TIGR00597
Reticulon; pfam02453
Reticulon; pfam02453
Reticulon; pfam02453
Protein phosphatase 2C; pfam00481
Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; cd00143
Protein serine/threonine phosphatase 2C, C-terminal domain; pfam07830
Enabled-VASP-type homology (EVH1) domain; cd01207
Optic atrophy 3 protein (OPA3); pfam07047
Optic atrophy 3 protein (OPA3); pfam07047
Olfactory receptor; cl10458
7 transmembrane receptor (rhodopsin family); pfam00001
HELP motif; pfam03451
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
HELP motif; pfam03451
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
HELP motif; pfam03451
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Domain present in hormone receptors; smart00008
7 transmembrane receptor (Secretin family); pfam00002
Sm protein D2; cd01720
Sm protein D2; cd01720
M28 Zn-Peptidase Glutaminyl Cyclase; cd03880
Zinc peptidases M18, M20, M28, and M42; cl14876
Zinc peptidases M18, M20, M28, and M42; cl14876
F-box-like; pfam12937
Homeodomain-containing transcription factor [Transcription]
Homeodomain;  DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner; cd00086
Catalytic domain of Myotonic Dystrophy protein kinase-like Protein Serine/Threonine Kinases; cd05597
Serine/Threonine protein kinases, catalytic domain; smart00220
DMPK coiled coil domain like; pfam08826
Catalytic domain of Myotonic Dystrophy protein kinase-like Protein Serine/Threonine Kinases; cd05597
Serine/Threonine protein kinases, catalytic domain; smart00220
DMPK coiled coil domain like; pfam08826
Catalytic domain of Myotonic Dystrophy protein kinase-like Protein Serine/Threonine Kinases; cd05597
Serine/Threonine protein kinases, catalytic domain; smart00220
DMPK coiled coil domain like; pfam08826
Catalytic domain of Myotonic Dystrophy protein kinase-like Protein Serine/Threonine Kinases; cd05597
Serine/Threonine protein kinases, catalytic domain; smart00220
DMPK coiled coil domain like; pfam08826
FOG: WD40 repeat [General function prediction only]
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; cl02567
Radial spokehead-like protein; pfam04712
Domain of unknown function (DUF3453); pfam11935
Symplekin tight junction protein C terminal; pfam12295
Forkhead (FH), also known as a 'winged helix'.  FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as...; cd00059
Interferon regulatory factor 2-binding protein zinc finger; pfam11261
RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in...; cl15348